valproic acid has been researched along with Adult Neuronal Ceroid Lipofuscinosis in 6 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An 11-year-old girl with juvenile neuronal ceroid lipofuscinosis developed acute pancreatitis secondary to valproic acid treatment, which resolved after discontinuation of the medication and conservative treatment." | 3.69 | Valproate-associated acute pancreatitis in a child with neuronal ceroid lipofuscinosis. ( Talwar, D, 1994) |
| " Chronic administration of lithium chloride or valproic acid, two clinically effective mood stabilizers, reverses the majority of these behavioral abnormalities." | 1.42 | Mice heterozygous for cathepsin D deficiency exhibit mania-related behavior and stress-induced depression. ( Duan, S; Han, Y; Li, X; Lou, H; Lu, Y; Zhen, X; Zhou, R; Zhu, L, 2015) |
| "Carnitine supplement was administrated in two patients, which resulted in resolution of symptoms and normalized ammonium levels." | 1.40 | Valproate-induced hyperammonemia in juvenile ceroid lipofuscinosis (Batten disease). ( Larsen, EP; Ostergaard, JR, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lv, Y | 1 |
| Zhang, N | 1 |
| Liu, C | 1 |
| Shi, M | 1 |
| Sun, L | 1 |
| Larsen, EP | 1 |
| Ostergaard, JR | 1 |
| Zhou, R | 1 |
| Lu, Y | 1 |
| Han, Y | 1 |
| Li, X | 1 |
| Lou, H | 1 |
| Zhu, L | 1 |
| Zhen, X | 1 |
| Duan, S | 1 |
| Johannsen, J | 1 |
| Nickel, M | 1 |
| Schulz, A | 1 |
| Denecke, J | 1 |
| Talwar, D | 1 |
| Aberg, LE | 1 |
| Bäckman, M | 1 |
| Kirveskari, E | 1 |
| Santavuori, P | 1 |
1 trial available for valproic acid and Adult Neuronal Ceroid Lipofuscinosis
| Article | Year |
|---|---|
Epilepsy and antiepileptic drug therapy in juvenile neuronal ceroid lipofuscinosis.
Topics: Adolescent; Adult; Age of Onset; Anticonvulsants; Child; Child, Preschool; Clonazepam; Comorbidity; | 2000 |
5 other studies available for valproic acid and Adult Neuronal Ceroid Lipofuscinosis
| Article | Year |
|---|---|
Occipital epilepsy versus progressive myoclonic epilepsy in a patient with continuous occipital spikes and photosensitivity in electroencephalogram: A case report.
Topics: Anticonvulsants; Atrophy; Cerebral Cortex; Diagnosis, Differential; Disease Progression; Electroence | 2018 |
Valproate-induced hyperammonemia in juvenile ceroid lipofuscinosis (Batten disease).
Topics: Adolescent; Anticonvulsants; Brain Diseases; Carnitine; Drug Therapy, Combination; Female; Humans; H | 2014 |
Mice heterozygous for cathepsin D deficiency exhibit mania-related behavior and stress-induced depression.
Topics: Adaptation, Ocular; Animals; Antidepressive Agents; Bipolar Disorder; Cathepsin D; Corticosterone; D | 2015 |
Considering Valproate as a Risk Factor for Rapid Exacerbation of Complex Movement Disorder in Progressed Stages of Late-Infantile CLN2 Disease.
Topics: Anticonvulsants; Child; Child, Preschool; Consciousness Disorders; Creatine Kinase; Deprescriptions; | 2016 |
Valproate-associated acute pancreatitis in a child with neuronal ceroid lipofuscinosis.
Topics: Acute Disease; Child; Female; Humans; Liver; Neuronal Ceroid-Lipofuscinoses; Pancreatitis; Seizures; | 1994 |