valproic acid has been researched along with Adipocere in 7 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Components of the mTOR pathway were assayed by Western blotting in postmortem fusiform gyrus samples from 11 subjects with idiopathic autism and 13 controls and in valproic acid versus saline-exposed rat neocortex." | 7.81 | Decreased mTOR signaling pathway in human idiopathic autism and in rats exposed to valproic acid. ( Ahn, Y; Fahnestock, M; Michalski, B; Nicolini, C; Rho, JM, 2015) |
| "Components of the mTOR pathway were assayed by Western blotting in postmortem fusiform gyrus samples from 11 subjects with idiopathic autism and 13 controls and in valproic acid versus saline-exposed rat neocortex." | 3.81 | Decreased mTOR signaling pathway in human idiopathic autism and in rats exposed to valproic acid. ( Ahn, Y; Fahnestock, M; Michalski, B; Nicolini, C; Rho, JM, 2015) |
| "Inositol was measured by gas chromatography." | 1.32 | Valproate decreases inositol biosynthesis. ( Agam, G; Belmaker, RH; Bialer, M; Dalton, E; Ding, D; Greenberg, ML; Harwood, AJ; Shaltiel, G; Shamir, A; Shapiro, J, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kiencke, V | 1 |
| Andresen-Streichert, H | 1 |
| Müller, A | 1 |
| Iwersen-Bergmann, S | 1 |
| Nicolini, C | 1 |
| Ahn, Y | 1 |
| Michalski, B | 1 |
| Rho, JM | 1 |
| Fahnestock, M | 1 |
| Pronicka, E | 1 |
| Weglewska-Jurkiewicz, A | 1 |
| Pronicki, M | 1 |
| Sykut-Cegielska, J | 1 |
| Kowalski, P | 1 |
| Pajdowska, M | 1 |
| Jankowska, I | 1 |
| Kotulska, K | 1 |
| Kalicinski, P | 1 |
| Jakobkiewicz-Banecka, J | 1 |
| Wegrzyn, G | 1 |
| Diem, O | 1 |
| Schäffner, M | 1 |
| Seifarth, W | 1 |
| Leib-Mösch, C | 1 |
| Jurata, LW | 1 |
| Bukhman, YV | 1 |
| Charles, V | 1 |
| Capriglione, F | 1 |
| Bullard, J | 1 |
| Lemire, AL | 1 |
| Mohammed, A | 1 |
| Pham, Q | 1 |
| Laeng, P | 1 |
| Brockman, JA | 1 |
| Altar, CA | 1 |
| Shaltiel, G | 1 |
| Shamir, A | 1 |
| Shapiro, J | 1 |
| Ding, D | 1 |
| Dalton, E | 1 |
| Bialer, M | 1 |
| Harwood, AJ | 1 |
| Belmaker, RH | 1 |
| Greenberg, ML | 1 |
| Agam, G | 1 |
| Martin del Rio, R | 1 |
| García-Gracia, M | 1 |
| Orensanz Muñoz, LM | 1 |
| DeFeudis, FV | 1 |
7 other studies available for valproic acid and Adipocere
| Article | Year |
|---|---|
Quantitative determination of valproic acid in postmortem blood samples--evidence of strong matrix dependency and instability.
Topics: Autopsy; Blood Preservation; Blood Specimen Collection; Death, Sudden; Dose-Response Relationship, D | 2013 |
Decreased mTOR signaling pathway in human idiopathic autism and in rats exposed to valproic acid.
Topics: Adolescent; Adult; Animals; Anticonvulsants; Autistic Disorder; Child; Child, Preschool; Disease Mod | 2015 |
Drug-resistant epilepsia and fulminant valproate liver toxicity. Alpers-Huttenlocher syndrome in two children confirmed post mortem by identification of p.W748S mutation in POLG gene.
Topics: Amino Acid Substitution; Child; Diffuse Cerebral Sclerosis of Schilder; DNA Polymerase gamma; DNA-Di | 2011 |
Influence of antipsychotic drugs on human endogenous retrovirus (HERV) transcription in brain cells.
Topics: Antipsychotic Agents; Brain; Cell Line, Tumor; Endogenous Retroviruses; Humans; Postmortem Changes; | 2012 |
Comparison of microarray-based mRNA profiling technologies for identification of psychiatric disease and drug signatures.
Topics: Adult; Aged; Bipolar Disorder; Enzyme Inhibitors; Female; Gene Expression; Humans; Male; Middle Aged | 2004 |
Valproate decreases inositol biosynthesis.
Topics: Amides; Animals; Animals, Newborn; Anticonvulsants; Blotting, Northern; Brain Chemistry; Cells, Cult | 2004 |
beta-Alanine and gamma-aminobutyric acid contents of rat brain; post-mortem changes and effects of aminooxyacetic acid and di-n-propylacetate.
Topics: 4-Aminobutyrate Transaminase; Alanine; Aminobutyrates; Aminooxyacetic Acid; Animals; Brain Chemistry | 1978 |