valproic acid has been researched along with Adhesions, Tissue in 3 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Delayed dosing did not reduce adhesions." | 1.40 | Histone deacetylase inhibitors decrease intra-abdominal adhesions with one intraoperative dose by reducing peritoneal fibrin deposition pathways. ( Cassidy, MR; Gainsbury, ML; Heydrick, S; Sheldon, HK; Sherburne, AC; Stucchi, AF, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, S | 1 |
| Liu, L | 1 |
| Jin, D | 1 |
| Zhang, Q | 1 |
| Takai, S | 1 |
| Cassidy, MR | 2 |
| Sherburne, AC | 2 |
| Sheldon, HK | 1 |
| Gainsbury, ML | 1 |
| Heydrick, S | 1 |
| Stucchi, AF | 2 |
| Heydrick, SJ | 1 |
3 other studies available for valproic acid and Adhesions, Tissue
| Article | Year |
|---|---|
The novel mechanism of valproate to prevent peritoneal adhesion formation.
Topics: Animals; Cecum; Cell Count; Cells, Cultured; Chymases; Cricetinae; Disease Models, Animal; Dose-Resp | 2020 |
Histone deacetylase inhibitors decrease intra-abdominal adhesions with one intraoperative dose by reducing peritoneal fibrin deposition pathways.
Topics: Animals; Benzamides; Fibrin; Fibrinogen; Histone Deacetylase Inhibitors; Hydroxamic Acids; Intestine | 2014 |
Combined intraoperative administration of a histone deacetylase inhibitor and a neurokinin-1 receptor antagonist synergistically reduces intra-abdominal adhesion formation in a rat model.
Topics: Abdomen; Animals; Disease Models, Animal; Drug Synergism; Fibrinogen; Histone Deacetylase Inhibitors | 2015 |