valproic acid has been researched along with Adenocarcinoma, Papillary in 3 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Adenocarcinoma, Papillary: An adenocarcinoma containing finger-like processes of vascular connective tissue covered by neoplastic epithelium, projecting into cysts or the cavity of glands or follicles. It occurs most frequently in the ovary and thyroid gland. (Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Valproic acid (VA) is an anticonvulsant that inhibits histone deacetylase activity at nontoxic concentrations." | 1.33 | Valproic acid inhibits growth, induces apoptosis, and modulates apoptosis-regulatory and differentiation gene expression in human thyroid cancer cells. ( Chung, WY; Clark, OH; Duh, QY; Kebebew, E; Shen, WT; Wong, MG; Wong, TS, 2005) |
| "Phenytoin levels were reduced to 37% of the original values, although the drug was given intravenously." | 1.27 | An interaction between cytostatic and anticonvulsant drugs. ( de Voogd-van der Straaten, I; Neef, C, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mitmaker, EJ | 1 |
| Griff, NJ | 1 |
| Grogan, RH | 1 |
| Sarkar, R | 1 |
| Kebebew, E | 2 |
| Duh, QY | 2 |
| Clark, OH | 2 |
| Shen, WT | 2 |
| Wong, TS | 1 |
| Chung, WY | 1 |
| Wong, MG | 1 |
| Neef, C | 1 |
| de Voogd-van der Straaten, I | 1 |
3 other studies available for valproic acid and Adenocarcinoma, Papillary
| Article | Year |
|---|---|
Modulation of matrix metalloproteinase activity in human thyroid cancer cell lines using demethylating agents and histone deacetylase inhibitors.
Topics: Adenocarcinoma, Follicular; Adenocarcinoma, Papillary; Antimetabolites, Antineoplastic; Azacitidine; | 2011 |
Valproic acid inhibits growth, induces apoptosis, and modulates apoptosis-regulatory and differentiation gene expression in human thyroid cancer cells.
Topics: Adenocarcinoma, Follicular; Adenocarcinoma, Papillary; Apoptosis; Apoptosis Regulatory Proteins; Cel | 2005 |
An interaction between cytostatic and anticonvulsant drugs.
Topics: Adenocarcinoma, Papillary; Adult; Altretamine; Antineoplastic Combined Chemotherapy Protocols; Carba | 1988 |