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valproic acid and Acquired Meningomyelocele

valproic acid has been researched along with Acquired Meningomyelocele in 8 studies

Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.

Research Excerpts

ExcerptRelevanceReference
"Fetal exposure to valproic acid has recently been associated with an increased incidence of neural tube defects."3.67Prenatal detection of a neural tube defect after fetal exposure to valproic acid. ( Campbell, WA; Cassidy, SB; Ciarleglio, L; Nochimson, DJ; Vintzileos, AM; Weinbaum, PJ, 1986)
"Valproic acid is an anticonvulsant that has been associated with open neural tube defects."2.38Valproic acid prenatal exposure. Association with lipomyelomeningocele. ( Carter, BS; Stewart, JM, 1989)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19906 (75.00)18.7374
1990's1 (12.50)18.2507
2000's0 (0.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sargar, KM1
Herman, TE1
Siegel, MJ1
Blaw, ME1
Woody, RC1
Philbert, A1
Pedersen, B1
Robert, E1
Robert, JM1
Lapras, C1
Graf, WD1
Pippenger, CE1
Shurtleff, DB1
Carter, BS1
Stewart, JM1
Serville, F1
Carles, D1
Guibaud, S1
Dallay, D1
Weinbaum, PJ1
Cassidy, SB1
Vintzileos, AM1
Campbell, WA1
Ciarleglio, L1
Nochimson, DJ1

Reviews

1 review available for valproic acid and Acquired Meningomyelocele

ArticleYear
Valproic acid prenatal exposure. Association with lipomyelomeningocele.
    Clinical pediatrics, 1989, Volume: 28, Issue:2

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Anticonvulsants; Cleft Palate; Female;

1989

Other Studies

7 other studies available for valproic acid and Acquired Meningomyelocele

ArticleYear
Valproate fetopathy.
    Journal of perinatology : official journal of the California Perinatal Association, 2015, Volume: 35, Issue:1

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Diagnostic Imaging; Epilepsy; Female; Fetal Di

2015
Valproic acid embryopathy?
    Neurology, 1983, Volume: 33, Issue:2

    Topics: Adolescent; Arnold-Chiari Malformation; Female; Humans; Meningomyelocele; Valproic Acid

1983
Treatment of epilepsy in women of child-bearing age: patients' opinion of teratogenic potential of valproate.
    Acta neurologica Scandinavica. Supplementum, 1983, Volume: 94

    Topics: Adolescent; Adult; Attitude; Drug Therapy, Combination; Epilepsy; Female; Humans; Infant, Newborn; M

1983
[Is valproic acid teratogenic?].
    Revue neurologique, 1983, Volume: 139, Issue:6-7

    Topics: Abnormalities, Drug-Induced; Adult; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Infa

1983
Erythrocyte antioxidant enzyme activities in children with myelomeningocele.
    Developmental medicine and child neurology, 1995, Volume: 37, Issue:10

    Topics: Adolescent; Adult; Child; Child, Preschool; Epilepsy; Erythrocytes; Female; Glutathione Peroxidase;

1995
Fetal valproate phenotype is recognisable by mid pregnancy.
    Journal of medical genetics, 1989, Volume: 26, Issue:5

    Topics: Abnormalities, Drug-Induced; Adult; Female; Fetal Diseases; Humans; Meningomyelocele; Phenotype; Pre

1989
Prenatal detection of a neural tube defect after fetal exposure to valproic acid.
    Obstetrics and gynecology, 1986, Volume: 67, Issue:3 Suppl

    Topics: Abortion, Therapeutic; Adolescent; Epilepsy; Female; Fetal Diseases; Humans; Hydrocephalus; Meningom

1986