valproic acid has been researched along with Acquired Immune Deficiency Syndrome in 6 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The AIDS Malignancy Consortium undertook a pilot trial of valproic acid among patients with AIDS-associated Kaposi sarcoma (KS)." | 7.75 | Molecular and clinical assessment in the treatment of AIDS Kaposi sarcoma with valproic Acid. ( Aboulafia, D; Ambinder, RF; Dezube, BJ; Dittmer, DP; Krown, SE; Lechowicz, M; Lee, JY; Ratner, L; Said, J; Wachsman, W, 2009) |
| "The AIDS Malignancy Consortium undertook a pilot trial of valproic acid among patients with AIDS-associated Kaposi sarcoma (KS)." | 3.75 | Molecular and clinical assessment in the treatment of AIDS Kaposi sarcoma with valproic Acid. ( Aboulafia, D; Ambinder, RF; Dezube, BJ; Dittmer, DP; Krown, SE; Lechowicz, M; Lee, JY; Ratner, L; Said, J; Wachsman, W, 2009) |
| "Among 1345 HIV/AIDS persons in active care between 2001 and 2007, 169 individuals were exposed to AEDs for the following indications: peripheral neuropathy/neuropathic pain (60%), seizure/epilepsy (24%), mood disorder (13%) and movement disorder (2%)." | 1.36 | Clinical outcomes and immune benefits of anti-epileptic drug therapy in HIV/AIDS. ( Gill, MJ; Krentz, HB; Lee, K; Maingat, F; Power, C; Siemieniuk, RA; Vivithanaporn, P, 2010) |
| "Valproic acid is an anticonvulsant drug known to inhibit the glucuronidation of zidovudine (AZT) in human liver microsomes." | 1.30 | Valproic acid increases cerebrospinal fluid zidovudine levels in a patient with AIDS. ( Akula, SK; Dejace, PM; Dreisbach, AW; Lertora, JJ; Rege, AB, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lechowicz, M | 1 |
| Dittmer, DP | 1 |
| Lee, JY | 1 |
| Krown, SE | 1 |
| Wachsman, W | 1 |
| Aboulafia, D | 1 |
| Dezube, BJ | 1 |
| Ratner, L | 1 |
| Said, J | 1 |
| Ambinder, RF | 1 |
| Lee, K | 1 |
| Vivithanaporn, P | 1 |
| Siemieniuk, RA | 1 |
| Krentz, HB | 1 |
| Maingat, F | 1 |
| Gill, MJ | 1 |
| Power, C | 1 |
| Nesseler, N | 1 |
| Polard, E | 1 |
| Arvieux, C | 1 |
| Coquerel, N | 1 |
| Michelet, C | 1 |
| Tattevin, P | 1 |
| Dewhurst, S | 1 |
| Maggirwar, SB | 1 |
| Schifitto, G | 1 |
| Gendelman, HE | 1 |
| Gelbard, HA | 1 |
| Akula, SK | 1 |
| Rege, AB | 1 |
| Dreisbach, AW | 1 |
| Dejace, PM | 1 |
| Lertora, JJ | 1 |
| Jefferson, JW | 1 |
1 review available for valproic acid and Acquired Immune Deficiency Syndrome
| Article | Year |
|---|---|
Glycogen synthase kinase 3 beta (GSK-3 beta) as a therapeutic target in neuroAIDS.
Topics: Acquired Immunodeficiency Syndrome; AIDS Dementia Complex; Animals; Anti-HIV Agents; Drug Delivery S | 2007 |
5 other studies available for valproic acid and Acquired Immune Deficiency Syndrome
| Article | Year |
|---|---|
Molecular and clinical assessment in the treatment of AIDS Kaposi sarcoma with valproic Acid.
Topics: Acquired Immunodeficiency Syndrome; Adult; Female; Herpesvirus 8, Human; Humans; Male; Middle Aged; | 2009 |
Clinical outcomes and immune benefits of anti-epileptic drug therapy in HIV/AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anticonvulsants; Calcium Channel Blockers; CD4 Antigens; | 2010 |
Aseptic meningitis associated with lamotrigine: report of two cases.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anticonvulsants; Blood; Blood Chemical Analysis; Cerebros | 2007 |
Valproic acid increases cerebrospinal fluid zidovudine levels in a patient with AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS Dementia Complex; Anticonvulsants; Drug Interactions | 1997 |
Possible risks associated with valproate treatment of AIDS-related mania.
Topics: Acquired Immunodeficiency Syndrome; Bipolar Disorder; Cytomegalovirus; Drug Costs; HIV-1; Humans; In | 1998 |