valproic acid has been researched along with Acoustic Neurinoma, Bilateral in 2 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Here, we show that VPA up-regulates the neurofibromatosis type 2 (NF2) tumor suppressor, merlin, to regulate neurite outgrowth through the interaction with paxillin." | 5.35 | Neurofibromatosis 2 tumor suppressor, the gene induced by valproic acid, mediates neurite outgrowth through interaction with paxillin. ( Kiyokawa, N; Kusakawa, S; Miyamoto, Y; Mizutani, R; Nakajima, H; Sanbe, A; Tanoue, A; Torii, T; Yamauchi, J, 2008) |
| "Here, we show that VPA up-regulates the neurofibromatosis type 2 (NF2) tumor suppressor, merlin, to regulate neurite outgrowth through the interaction with paxillin." | 1.35 | Neurofibromatosis 2 tumor suppressor, the gene induced by valproic acid, mediates neurite outgrowth through interaction with paxillin. ( Kiyokawa, N; Kusakawa, S; Miyamoto, Y; Mizutani, R; Nakajima, H; Sanbe, A; Tanoue, A; Torii, T; Yamauchi, J, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Subbiah, V | 1 |
| Slopis, J | 1 |
| Hong, DS | 1 |
| Ketonen, LM | 1 |
| Hamilton, J | 1 |
| McCutcheon, IE | 1 |
| Kurzrock, R | 1 |
| Yamauchi, J | 1 |
| Miyamoto, Y | 1 |
| Kusakawa, S | 1 |
| Torii, T | 1 |
| Mizutani, R | 1 |
| Sanbe, A | 1 |
| Nakajima, H | 1 |
| Kiyokawa, N | 1 |
| Tanoue, A | 1 |
1 trial available for valproic acid and Acoustic Neurinoma, Bilateral
| Article | Year |
|---|---|
Treatment of patients with advanced neurofibromatosis type 2 with novel molecularly targeted therapies: from bench to bedside.
Topics: Adolescent; Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents | 2012 |
1 other study available for valproic acid and Acoustic Neurinoma, Bilateral
| Article | Year |
|---|---|
Neurofibromatosis 2 tumor suppressor, the gene induced by valproic acid, mediates neurite outgrowth through interaction with paxillin.
Topics: Animals; Anticonvulsants; Carrier Proteins; Cell Line; Genes, Neurofibromatosis 2; Genes, Tumor Supp | 2008 |