valproic acid has been researched along with Acidosis, Lactic in 9 studies
Valproic Acid: A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.
valproic acid : A branched-chain saturated fatty acid that comprises of a propyl substituent on a pentanoic acid stem.
Acidosis, Lactic: Acidosis caused by accumulation of lactic acid more rapidly than it can be metabolized. It may occur spontaneously or in association with diseases such as DIABETES MELLITUS; LEUKEMIA; or LIVER FAILURE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Levetiracetam (LEV) is an AED that is neuroprotective in various neurologic disorders." | 5.51 | Levetiracetam administration is correlated with lower mortality in patients with mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes: a retrospective study. ( Bao, XH; Wang, ZX; Xiong, H; Yuan, Y; Zhang, X; Zhang, Z; Zhao, DH; Zhao, XT, 2019) |
| "A 25-year-old white woman with a history of multiple suicide attempts and schizophrenia presented after ingesting an unknown amount of valproic acid." | 3.70 | High-flux hemodialysis without hemoperfusion is effective in acute valproic acid overdose. ( Constantiner, M; Kane, SL; Meinecke, CD; Sedor, JR; Staubus, AE, 2000) |
| "Levetiracetam (LEV) is an AED that is neuroprotective in various neurologic disorders." | 1.51 | Levetiracetam administration is correlated with lower mortality in patients with mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes: a retrospective study. ( Bao, XH; Wang, ZX; Xiong, H; Yuan, Y; Zhang, X; Zhang, Z; Zhao, DH; Zhao, XT, 2019) |
| "We reported a case of MELAS that presented right distal internal carotid arterial (ICA) stenosis and reviewed 12 similar previously reported cases involving intracranial large blood vessels." | 1.48 | MELAS and macroangiopathy: A case report and literature review. ( Fu, H; Jiang, G; Ju, X; Sun, X, 2018) |
| "The valproic acid plasma level was very high (1437 μg/mL), confirming it was a severe intoxication." | 1.37 | [Acute valproic acid intoxication: interest of a treatment by extracoporeal elimination combined with L-carnitine]. ( Alluin, A; Canevet, C; Desmaretz, JL; Gauthier, N; Jezequel, J, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 5 (55.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sun, X | 1 |
| Jiang, G | 1 |
| Ju, X | 1 |
| Fu, H | 1 |
| Zhang, Z | 1 |
| Zhao, DH | 1 |
| Zhao, XT | 1 |
| Zhang, X | 1 |
| Xiong, H | 1 |
| Bao, XH | 1 |
| Yuan, Y | 1 |
| Wang, ZX | 1 |
| Jackson, R | 1 |
| Toubia, N | 1 |
| Dhaliwal, G | 1 |
| Bottomley, SS | 1 |
| Bronze, MS | 1 |
| Deras, P | 1 |
| Gignon, L | 1 |
| Toumi, M | 1 |
| Louart, G | 1 |
| Muller, L | 1 |
| Boyer, JC | 1 |
| Lefrant, JY | 1 |
| Alluin, A | 1 |
| Jezequel, J | 1 |
| Gauthier, N | 1 |
| Desmaretz, JL | 1 |
| Canevet, C | 1 |
| Davison, AS | 1 |
| Milan, AM | 1 |
| Roberts, NB | 1 |
| Azaroual, N | 1 |
| Cartigny, B | 1 |
| Imbenotte, M | 1 |
| Vallée, L | 1 |
| Vermeersch, G | 1 |
| Lhermitte, M | 1 |
| Kane, SL | 1 |
| Constantiner, M | 1 |
| Staubus, AE | 1 |
| Meinecke, CD | 1 |
| Sedor, JR | 1 |
| Walker, UA | 1 |
| Venhoff, N | 1 |
9 other studies available for valproic acid and Acidosis, Lactic
| Article | Year |
|---|---|
MELAS and macroangiopathy: A case report and literature review.
Topics: Acidosis, Lactic; Adult; Arginine; Ascorbic Acid; Carotid Stenosis; Humans; Male; MELAS Syndrome; Mi | 2018 |
Levetiracetam administration is correlated with lower mortality in patients with mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes: a retrospective study.
Topics: Acidosis, Lactic; Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Female; Human | 2019 |
A confusing case of confusion. Acute porphyrias.
Topics: Acidosis, Lactic; Acute Disease; Anticonvulsants; Brain; Confusion; Diagnosis, Differential; Diet, R | 2008 |
[Lactic acidosis after voluntary intoxication with valproic acid].
Topics: Acidosis, Lactic; Acute Kidney Injury; Adult; Combined Modality Therapy; Depressive Disorder; Emerge | 2010 |
[Acute valproic acid intoxication: interest of a treatment by extracoporeal elimination combined with L-carnitine].
Topics: Acidosis, Lactic; Acute Lung Injury; Anticonvulsants; Carnitine; Cranial Nerve Diseases; Electroence | 2011 |
The consequences of valproate overdose.
Topics: Acid-Base Equilibrium; Acidosis, Lactic; Adult; Anticonvulsants; Carnitine; Drug Overdose; Epilepsy; | 2011 |
[Analysis of two cases of valproic acid intoxication by 1H NMR spectroscopy and gas chromatography/mass spectrometry].
Topics: Acidosis, Lactic; Adolescent; Adult; Anticonvulsants; Gas Chromatography-Mass Spectrometry; Glucuron | 1999 |
High-flux hemodialysis without hemoperfusion is effective in acute valproic acid overdose.
Topics: Acidosis, Lactic; Adult; Algorithms; Anticonvulsants; Drug Overdose; Female; Half-Life; Hemodynamics | 2000 |
Multiple mitochondrial DNA deletions and lactic acidosis in an HIV-infected patient under antiretroviral therapy.
Topics: Acidosis, Lactic; Anti-HIV Agents; Cell Line; DNA, Mitochondrial; Drug Therapy, Combination; Enzyme | 2001 |