valinomycin and Ischemia

valinomycin has been researched along with Ischemia* in 2 studies

Other Studies

2 other study(ies) available for valinomycin and Ischemia

Article	Year
Reversal of ischemic mitochondrial dysfunction. The Journal of biological chemistry, 1981, Apr-10, Volume: 256, Issue:7 Topics: Animals; Calcium; Female; Ischemia; Kinetics; Liver; Magnesium; Membrane Potentials; Mitochondria; Mitochondria, Liver; Mitochondrial Swelling; Palmitoyl Coenzyme A; Polyethylene Glycols; Potassium; Rats; Sodium; Valinomycin	1981
Studies on the pathogenesis of ischemic cell injury. VII. Proton gradient and respiration of renal tissue cubes, renal mitochondrial and submitochondrial particles following ischemic cell injury. Beitrage zur Pathologie, 1977, Volume: 161, Issue:3 Electron transport in tissue cubes, isolated mitochondria and submitochondria particles were examined as a function of ischemic time. It was found that electron transport remains active in all systems beyond the 2 hour ischemic time interval. The NADH stimulated respiration, however, declined after 2 hours of ischemia in ASU (Ammonia-Sephadex-Urea) particles followed by respiration with matrix-located dehydrogenases tested by substrates such as glutamate, alpha-ketoglutarate and pyruvate plus malate. Succinate dependent respiration remains active at control levels. In contrast proton gradient reveals changes in two phases: Phase A is characterized by gradually increasing gradient without valinomycin and by a rapidly declining gradient with valinomycin in the medium. Phase B is characterized by a declining proton gradient with or without valinomycin. It is suggested that the alteration of the proton gradient between 1 and 2 hours ischemia is an important factor contributing to irreversible cell injury. Topics: Animals; Ischemia; Kidney; Mitochondria; Oxygen Consumption; Protons; Rats; Time Factors; Valinomycin	1977

Article

Year

Reversal of ischemic mitochondrial dysfunction.

The Journal of biological chemistry, 1981, Apr-10, Volume: 256, Issue:7

Topics: Animals; Calcium; Female; Ischemia; Kinetics; Liver; Magnesium; Membrane Potentials; Mitochondria; Mitochondria, Liver; Mitochondrial Swelling; Palmitoyl Coenzyme A; Polyethylene Glycols; Potassium; Rats; Sodium; Valinomycin

1981

Studies on the pathogenesis of ischemic cell injury. VII. Proton gradient and respiration of renal tissue cubes, renal mitochondrial and submitochondrial particles following ischemic cell injury.

Beitrage zur Pathologie, 1977, Volume: 161, Issue:3

Electron transport in tissue cubes, isolated mitochondria and submitochondria particles were examined as a function of ischemic time. It was found that electron transport remains active in all systems beyond the 2 hour ischemic time interval. The NADH stimulated respiration, however, declined after 2 hours of ischemia in ASU (Ammonia-Sephadex-Urea) particles followed by respiration with matrix-located dehydrogenases tested by substrates such as glutamate, alpha-ketoglutarate and pyruvate plus malate. Succinate dependent respiration remains active at control levels. In contrast proton gradient reveals changes in two phases: Phase A is characterized by gradually increasing gradient without valinomycin and by a rapidly declining gradient with valinomycin in the medium. Phase B is characterized by a declining proton gradient with or without valinomycin. It is suggested that the alteration of the proton gradient between 1 and 2 hours ischemia is an important factor contributing to irreversible cell injury.

Topics: Animals; Ischemia; Kidney; Mitochondria; Oxygen Consumption; Protons; Rats; Time Factors; Valinomycin

1977