Compounds > valine

valine and Parkinson Disease

valine has been researched along with Parkinson Disease in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.94)18.7374
1990's1 (2.94)18.2507
2000's12 (35.29)29.6817
2010's20 (58.82)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chatterji, T; Gupta, M; Nagesh Babu, G; Paliwal, VK; Roy, R; Singh, S1
Jiang, SD; Pan, CD; Tan, LM; Tang, KY; Tang, MS; Wang, YC; Xiao, J; Yan, ZR; Zheng, ZJ; Zou, YB1
Sun, HM; Wang, ZZ; Zhang, Y1
Ahmad-Annuar, A; Aziz, ZA; Chong, YB; Eow, GB; Gopalai, AA; Kuppusamy, R; Li, HH; Lim, SK; Lim, SY; Lim, TT; Norlinah, MI; Puvanarajah, S; Tan, AH; Tan, CT; Tan, LP; Viswanathan, S; Zhao, Y1
Kolisek, M; Launay, P; Mastrototaro, L; Schweigel-Röntgen, M; Smorodchenko, A; Sponder, G; Vormann, J1
Chen, SD; Dong, F; Liu, J; Quinn, TJ; Wang, Y; Wu, H; Xiao, Q; Yang, Q; Zhao, J1
Chen, P; Guo, M; Li, L; Liu, J; Lu, L1
Bucossi, S; Mariani, S; R, RS; Simonelli, I; Siotto, M; Ventriglia, M1
Brice, A; Cormier-Dequaire, F; Corvol, JC; Gharrad, I; Habert, MO; Hartmann, A; Kas, A; Mallet, A; Martini, JB; Meier, N; Muellner, J; Schuepbach, M; Tahiri, K; Vidailhet, M1
Cintra, AC; Martins, NM; Sampaio, SV; Santos, AC; Santos, NA; Sartim, MA1
Feng, S; Gan, R; Gao, L; Nie, K; Tang, H; Wang, L; Zhang, Y; Zhao, J; Zhao, X; Zhu, R1
Barbosa, MR; Cagni, FC; Campêlo, CLDC; Coimbra, DG; Gomes de Andrade, T; Júnior, COG; Júnior, LGO; Neto, ABS; Ribeiro, AM; Silva, RH1
Barker, RA; Bishop, S; Fallon, S; Hughes, L; Owen, AM; Rowe, JB; Williams-Gray, CH1
Kumar, S; Sarkar, A; Sundar, D1
D'Alfonso, S; Hicks, TP; Jacobsen, KX; Main, CD; Payne, KB; Poulter, MO; Staines, WA; Steiner, JP1
Chen, ML; Hu, FC; Lin, CH; Tai, CH; Wu, RM1
Agid, Y; Bellanger, A; Ben Djebara, M; Bonnet, AM; Bonnet, C; Charbonnier-Beaupel, F; Corvol, JC; Costentin, J; Fiévet, MH; Hartmann, A; Hulot, JS; Lacomblez, L; Meliksetyan, G; Roze, E; Vidailhet, M; Vrignaud, C; Zahr, N1
de Lau, LM; Heutink, P; Marinus, J; van Hilten, JJ; Verbaan, D1
Collins, JJ; Ferree, A; Guillily, M; Li, H; Smith, K; Squillace, R; Takashima, A; Weigele, M; Wolozin, B1
Barker, RA; Bose, SK; Brooks, DJ; O'Keeffe, D; O'Keeffe, GC; Piccini, P; Politis, M; Robbins, TW; Wu, K1
Djuric, G; Dobricic, V; Jankovic, M; Kostic, VS; Kresojevic, N; Novakovic, I; Pekmezovic, T; Petrovic, I; Stefanova, E; Svetel, MV; Tomic, A1
Cheng, CY; Hong, CJ; Lin, CH; Liu, HC; Liu, TY; Tsai, SJ1
Harada, S; Hayashi, A; Nakamura, T; Ohkoshi, N; Shoji, S; Watanabe, M; Yoshizawa, K1
Barker, RA; Blackwell, AD; Foltynie, T; Goldberg, TE; Kolachana, BS; Lewis, SG; Robbins, TW; Weinberger, DR2
Kaji, R; Kawakami, H; Kuno, S; Nishimura, M1
Kobayashi, N; Ochiai, S; Sode, K; Usuzaka, E1
Bax, A; Ulmer, TS1
Chang, KH; Chao, CY; Chen, CM; Chen, IC; Chen, YC; Hu, FJ; Lee-Chen, GJ; Liu, YT; Lyu, RK; Wu, YR1
Barker, RA; Hampshire, A; Owen, AM; Robbins, TW; Williams-Gray, CH1
Ho, SL; Li, LS; Ma, OC; Xie, T1
Kuroda, Y; Satoh, J1
Abe, H; Doh-ura, K; Iida, T; Iwaki, T; Kawashima, T1
Bruck, J; Gerstenbrand, F; Gnad, H; Gründig, E; Prosenz, P; Simanyi, M1

Reviews

3 review(s) available for valine and Parkinson Disease

ArticleYear
COMT Val158Met polymorphism and Parkinson's disease risk: a pooled analysis in different populations.
    Neurological research, 2019, Volume: 41, Issue:4

    Topics: Catechol O-Methyltransferase; Databases, Bibliographic; Female; Genetic Predisposition to Disease; Global Health; Humans; Male; Methionine; Parkinson Disease; Polymorphism, Single Nucleotide; Valine

2019
A meta-analysis of the relationship of the Parkin p.Val380Leu polymorphism to Parkinson's disease.
    American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2013, Volume: 162B, Issue:3

    Topics: Adult; Age of Onset; Aged; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Heterozygote; Homozygote; Humans; Leucine; Male; Middle Aged; Odds Ratio; Parkinson Disease; Polymorphism, Genetic; Ubiquitin-Protein Ligases; Valine

2013
Meta-analysis study on the role of bone-derived neurotrophic factor Val66Met polymorphism in Parkinson's disease.
    Rejuvenation research, 2015, Volume: 18, Issue:1

    Topics: Alleles; Brain-Derived Neurotrophic Factor; Case-Control Studies; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Homozygote; Humans; Methionine; Parkinson Disease; Polymorphism, Single Nucleotide; Regression Analysis; Valine

2015

Trials

2 trial(s) available for valine and Parkinson Disease

ArticleYear
Dopaminergic denervation severity depends on COMT Val158Met polymorphism in Parkinson's disease.
    Parkinsonism & related disorders, 2015, Volume: 21, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Catechol O-Methyltransferase; Corpus Striatum; Denervation; Dopaminergic Neurons; Female; Humans; Male; Methionine; Middle Aged; Parkinson Disease; Polymorphism, Single Nucleotide; Tomography, Emission-Computed, Single-Photon; Valine

2015
The COMT Val158Met polymorphism affects the response to entacapone in Parkinson's disease: a randomized crossover clinical trial.
    Annals of neurology, 2011, Volume: 69, Issue:1

    Topics: Aged; Antiparkinson Agents; Biological Availability; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Catechols; Cross-Over Studies; Double-Blind Method; Enzyme Inhibitors; Female; Genotype; Humans; Levodopa; Male; Methionine; Middle Aged; Nitriles; Parkinson Disease; Pharmacogenetics; Polymorphism, Genetic; Valine

2011

Other Studies

29 other study(ies) available for valine and Parkinson Disease

ArticleYear
Serum metabolomics study in a group of Parkinson's disease patients from northern India.
    Clinica chimica acta; international journal of clinical chemistry, 2018, Volume: 480

    Topics: Aged; Alanine; Female; Glutamine; Histidine; Humans; India; Isoleucine; Male; Metabolomics; Middle Aged; Multiple System Atrophy; Parkinson Disease; Proton Magnetic Resonance Spectroscopy; Supranuclear Palsy, Progressive; Valine

2018
Lack of association between the LRRK2 A419V variant and Asian Parkinson's disease.
    Annals of the Academy of Medicine, Singapore, 2013, Volume: 42, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alanine; Case-Control Studies; China; Cohort Studies; Cytosine; Female; Gene Frequency; Genetic Variation; Genotype; Heterozygote; Humans; India; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Malaysia; Male; Middle Aged; Parkinson Disease; Polymorphism, Genetic; Protein Serine-Threonine Kinases; Risk Factors; Singapore; Thymine; Valine; Young Adult

2013
Substitution p.A350V in Na⁺/Mg²⁺ exchanger SLC41A1, potentially associated with Parkinson's disease, is a gain-of-function mutation.
    PloS one, 2013, Volume: 8, Issue:8

    Topics: Alanine; Amino Acid Substitution; Cation Transport Proteins; Cations, Divalent; Cations, Monovalent; Cell Adhesion; Cell Proliferation; Cyclic AMP; Gene Expression Regulation; HEK293 Cells; Humans; Ion Transport; Magnesium; Mutation; Parkinson Disease; Phosphorylation; Sodium; Transfection; Valine

2013
Catechol-O-methyltransferase Val158Met polymorphism: modulation of wearing-off susceptibility in a Chinese cohort of Parkinson's disease.
    Parkinsonism & related disorders, 2014, Volume: 20, Issue:10

    Topics: Aged; Asian People; Catechol O-Methyltransferase; Cohort Studies; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Humans; Male; Methionine; Middle Aged; Parkinson Disease; Polymorphism, Single Nucleotide; Valine

2014
Association of COMT Val158Met polymorphism with wearing-off susceptibility in Parkinson's disease.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2015, Volume: 36, Issue:4

    Topics: Catechol O-Methyltransferase; Databases, Bibliographic; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Humans; Japan; Male; Methionine; Parkinson Disease; Polymorphism, Single Nucleotide; Valine

2015
A tripeptide isolated from Bothrops atrox venom has neuroprotective and neurotrophic effects on a cellular model of Parkinson's disease.
    Chemico-biological interactions, 2015, Jun-25, Volume: 235

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Bothrops; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dopamine; Dopaminergic Neurons; Glutamic Acid; Mitochondria; Models, Biological; Neuroprotective Agents; Parkinson Disease; PC12 Cells; Peptides; Rats; Tryptophan; Valine; Venoms

2015
Catechol-O-methyltransferase Val158Met polymorphism influences prefrontal executive function in early Parkinson's disease.
    Journal of the neurological sciences, 2016, Oct-15, Volume: 369

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Catechol O-Methyltransferase; Cognition Disorders; Executive Function; Female; Gene Frequency; Genotype; Humans; Male; Methionine; Middle Aged; Neuropsychological Tests; Parkinson Disease; Polymorphism, Genetic; Severity of Illness Index; Valine; Wechsler Scales; Young Adult

2016
Association of BDNF Val66MET Polymorphism With Parkinson's Disease and Depression and Anxiety Symptoms.
    The Journal of neuropsychiatry and clinical neurosciences, 2017,Spring, Volume: 29, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anxiety; Brain-Derived Neurotrophic Factor; Depression; Disease Progression; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Humans; Male; Methionine; Middle Aged; Parkinson Disease; Polymorphism, Genetic; Valine

2017
The val158met COMT polymorphism's effect on atrophy in healthy aging and Parkinson's disease.
    Neurobiology of aging, 2010, Volume: 31, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Atrophy; Catechol O-Methyltransferase; Female; Genotype; Humans; Magnetic Resonance Imaging; Male; Methionine; Middle Aged; Parkinson Disease; Polymorphism, Genetic; Prefrontal Cortex; Regression Analysis; Valine; Young Adult

2010
Controlling aggregation propensity in A53T mutant of alpha-synuclein causing Parkinson's disease.
    Biochemical and biophysical research communications, 2009, Sep-18, Volume: 387, Issue:2

    Topics: alpha-Synuclein; Amino Acid Substitution; Humans; Mutation; Parkinson Disease; Protein Stability; Protein Structure, Secondary; Solubility; Thermodynamics; Valine

2009
GPI-1046 increases presenilin-1 expression and restores NMDA channel activity.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2010, Volume: 37, Issue:4

    Topics: Adrenergic Agents; Animals; Corpus Striatum; Disease Models, Animal; Excitatory Amino Acid Antagonists; Functional Laterality; In Vitro Techniques; Male; Membrane Potentials; Neurons; Oxidopamine; Parkinson Disease; Patch-Clamp Techniques; Presenilin-1; Pyrrolidines; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Tyrosine 3-Monooxygenase; Up-Regulation; Valine

2010
Lrrk2 S1647T and BDNF V66M interact with environmental factors to increase risk of Parkinson's disease.
    Parkinsonism & related disorders, 2011, Volume: 17, Issue:2

    Topics: Aged; Brain-Derived Neurotrophic Factor; Environmental Exposure; Female; Genetic Association Studies; Genetic Variation; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Methionine; Middle Aged; Parkinson Disease; Protein Serine-Threonine Kinases; Risk Factors; Taiwan; Valine

2011
Catechol-O-methyltransferase Val158Met and the risk of dyskinesias in Parkinson's disease.
    Movement disorders : official journal of the Movement Disorder Society, 2012, Volume: 27, Issue:1

    Topics: Aged; Antiparasitic Agents; Catechol O-Methyltransferase; Cohort Studies; Dyskinesia, Drug-Induced; Dyskinesias; Female; Genetic Predisposition to Disease; Genotype; Humans; Male; Methionine; Middle Aged; Parkinson Disease; Polymorphism, Genetic; Proportional Hazards Models; Valine

2012
Regulation of physiologic actions of LRRK2: focus on autophagy.
    Neuro-degenerative diseases, 2012, Volume: 10, Issue:1-4

    Topics: Animals; Animals, Genetically Modified; Autophagy; Caenorhabditis elegans; Disease Models, Animal; Gene Expression Regulation; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Methionine; Mutation; Parkinson Disease; Protein Serine-Threonine Kinases; Sirolimus; tau Proteins; Valine

2012
The catechol-O-methyltransferase Val(158)Met polymorphism modulates fronto-cortical dopamine turnover in early Parkinson's disease: a PET study.
    Brain : a journal of neurology, 2012, Volume: 135, Issue:Pt 8

    Topics: Aged; Catechol O-Methyltransferase; Corpus Striatum; Dopamine; Female; Frontal Lobe; Genetic Variation; Genotype; Humans; Male; Methionine; Middle Aged; Parkinson Disease; Polymorphism, Genetic; Positron-Emission Tomography; Valine

2012
A common polymorphism in the brain-derived neurotrophic factor gene in patients with adult-onset primary focal and segmental dystonia.
    Acta neurologica Belgica, 2013, Volume: 113, Issue:3

    Topics: Adult; Age of Onset; Analysis of Variance; Brain-Derived Neurotrophic Factor; DNA Mutational Analysis; Dystonic Disorders; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Male; Methionine; Middle Aged; Odds Ratio; Parkinson Disease; Polymorphism, Single Nucleotide; Valine

2013
Brain-derived neurotrophic factor (BDNF) Val66Met polymorphisms in Parkinson's disease and age of onset.
    Neuroscience letters, 2003, Dec-15, Volume: 353, Issue:1

    Topics: Age of Onset; Aged; Brain-Derived Neurotrophic Factor; Case-Control Studies; Female; Gene Frequency; Genotype; Humans; Male; Methionine; Middle Aged; Parkinson Disease; Polymorphism, Genetic; Taiwan; Valine

2003
Association between catechol-O-methyltransferase gene polymorphisms and wearing-off and dyskinesia in Parkinson's disease.
    Neuropsychobiology, 2003, Volume: 48, Issue:4

    Topics: Aged; Catechol O-Methyltransferase; Dyskinesias; Exons; Fatigue Syndrome, Chronic; Female; Genotype; Humans; Male; Methionine; Parkinson Disease; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Polymorphism, Single-Stranded Conformational; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Analysis, DNA; Valine

2003
Planning ability in Parkinson's disease is influenced by the COMT val158met polymorphism.
    Movement disorders : official journal of the Movement Disorder Society, 2004, Volume: 19, Issue:8

    Topics: Adult; Aged; Amino Acid Substitution; Catechol O-Methyltransferase; Concept Formation; Demography; Female; Genotype; Humans; Male; Methionine; Middle Aged; Neuropsychological Tests; Parkinson Disease; Polymorphism, Genetic; Valine

2004
The BDNF Val66Met polymorphism has a gender specific influence on planning ability in Parkinson's disease.
    Journal of neurology, 2005, Volume: 252, Issue:7

    Topics: Aged; Analysis of Variance; Brain-Derived Neurotrophic Factor; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Male; Mental Processes; Methionine; Middle Aged; Neuropsychological Tests; Parkinson Disease; Polymorphism, Genetic; Sex Characteristics; Valine

2005
Brain-derived neurotrophic factor gene polymorphisms in Japanese patients with sporadic Alzheimer's disease, Parkinson's disease, and multiple system atrophy.
    Movement disorders : official journal of the Movement Disorder Society, 2005, Volume: 20, Issue:8

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Brain-Derived Neurotrophic Factor; Cysteine; Female; Genetic Predisposition to Disease; Humans; Japan; Male; Methionine; Middle Aged; Multiple System Atrophy; Parkinson Disease; Polymorphism, Genetic; Threonine; Valine

2005
Engineered alpha-synuclein prevents wild type and familial Parkin variant fibril formation.
    Biochemical and biophysical research communications, 2005, Sep-23, Volume: 335, Issue:2

    Topics: alpha-Synuclein; Alzheimer Disease; Amino Acid Sequence; Amyloid; Bone Marrow Cells; Circular Dichroism; DNA; DNA, Complementary; Gene Library; Humans; Light; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Nerve Tissue Proteins; Parkinson Disease; Peptides; Polymerase Chain Reaction; Proline; Protein Binding; Protein Conformation; Protein Engineering; Protein Structure, Secondary; Scattering, Radiation; Synucleins; Time Factors; Ubiquitin-Protein Ligases; Ultraviolet Rays; Valine

2005
Comparison of structure and dynamics of micelle-bound human alpha-synuclein and Parkinson disease variants.
    The Journal of biological chemistry, 2005, Dec-30, Volume: 280, Issue:52

    Topics: Alanine; alpha-Synuclein; Amino Acid Sequence; Humans; Kinetics; Magnetic Resonance Spectroscopy; Micelles; Models, Molecular; Molecular Conformation; Molecular Sequence Data; Mutation; Parkinson Disease; Point Mutation; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Serine; Sodium Dodecyl Sulfate; Valine

2005
Nuclear receptor NR4A2 IVS6 +18insG and brain derived neurotrophic factor (BDNF) V66M polymorphisms and risk of Taiwanese Parkinson's disease.
    American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2007, Jun-05, Volume: 144B, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Asian People; Brain-Derived Neurotrophic Factor; Case-Control Studies; DNA-Binding Proteins; Female; Genetic Predisposition to Disease; Humans; Male; Methionine; Middle Aged; Nuclear Receptor Subfamily 4, Group A, Member 2; Parkinson Disease; Polymorphism, Genetic; Risk Factors; Sex Characteristics; Taiwan; Transcription Factors; Valine

2007
Catechol O-methyltransferase Val158Met genotype influences frontoparietal activity during planning in patients with Parkinson's disease.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, May-02, Volume: 27, Issue:18

    Topics: Aged; Brain Mapping; Catechol O-Methyltransferase; Female; Frontal Lobe; Genotype; Humans; Male; Methionine; Middle Aged; Parietal Lobe; Parkinson Disease; Polymorphism, Genetic; Problem Solving; Valine

2007
G/A1947 polymorphism in catechol-O-methyltransferase (COMT) gene in Parkinson's disease.
    Movement disorders : official journal of the Movement Disorder Society, 1997, Volume: 12, Issue:3

    Topics: Aged; Alleles; Base Sequence; Catechol O-Methyltransferase; DNA Primers; Female; Humans; Male; Methionine; Middle Aged; Molecular Sequence Data; Parkinson Disease; Polymerase Chain Reaction; Polymorphism, Genetic; Valine

1997
A valine to methionine polymorphism at codon 83 in the 8-oxo-dGTPase gene MTH1 is not associated with sporadic Parkinson's disease.
    European journal of neurology, 2000, Volume: 7, Issue:6

    Topics: Aged; Aged, 80 and over; Amino Acid Substitution; DNA Repair Enzymes; Exons; Female; Humans; Male; Methionine; Middle Aged; Parkinson Disease; Phosphoric Monoester Hydrolases; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Reference Values; Valine

2000
An atypical case of sporadic Creutzfeldt-Jakob disease with Parkinson's disease.
    Neuropathology : official journal of the Japanese Society of Neuropathology, 2001, Volume: 21, Issue:4

    Topics: Aged; Atrophy; Cerebral Cortex; Creutzfeldt-Jakob Syndrome; Fatal Outcome; Female; Genetic Carrier Screening; Humans; Middle Aged; Parkinson Disease; Prions; Valine

2001
[The effect of the administration of amino acids, especially of L-dopa and alpha-methyldopa, on the composition of cerebrospinal fluid in extrapyramidal syndromes. II. Alterations of cerebrospinal fluid in patients with Parkinson's disease and chorea fol
    Deutsche Zeitschrift fur Nervenheilkunde, 1969, Volume: 196, Issue:3

    Topics: Alanine Transaminase; Amino Acids; Aspartate Aminotransferases; Chorea; Humans; Methyldopa; Parkinson Disease; Valine

1969