valine and Obesity

valine has been researched along with Obesity in 65 studies

Research

Studies (65)

Timeframe	Studies, this research(%)	All Research%
pre-1990	15 (23.08)	18.7374
1990's	3 (4.62)	18.2507
2000's	16 (24.62)	29.6817
2010's	20 (30.77)	24.3611
2020's	11 (16.92)	2.80

Authors

Authors	Studies
Bulló, M; Halford, JCG; Hansen, TT; Harrold, JA; Papandreou, C; Sjödin, A	1
Bishop, CA; Grune, T; Henkel, J; Henning, T; Klaus, S; Machate, T; Püschel, G; Weber, D; Weitkunat, K	1
Caspers, MPM; Gart, E; Keijer, J; Kleemann, R; Menke, A; Morrison, MC; Salic, K; Snabel, J; van Duyvenvoorde, W; van Trigt, N	1
Chen, S; Eguchi, M; Fukunaga, A; Kabe, I; Kochi, T; Miki, T; Mizoue, T; Nanri, A	1
Lenart-Lipinska, M; Matyjaszek-Matuszek, B; Szmygin, H; Szydelko, J; Wozniak, S	1
Bloks, VW; C L van den Munckhof, I; Chen, L; Doestzada, M; Fu, J; Joosten, LAB; Kuipers, F; Kurilshikov, A; Netea, MG; Riksen, NP; Rutten, JHW; van Faassen, M; Wang, D; Wijmenga, C; Zhernakova, A; Zhernakova, DV	1
Alvarez, M; André Drevon, C; Birkeland, KI; Bjune, MS; Claussnitzer, M; Dankel, SN; Heinonen, S; Jersin, RÅ; Lee-Ødegård, S; McCann, A; Mellgren, G; Muniandy, M; Pajukanta, P; Pietiläinen, KH; Skartveit, L; Sri Priyanka Tallapragada, D	1
Atwal, PS; Bersten, DC; Blackburn, PR; Caulfield, TR; Cooiman, M; Gerassimou, AG; Harris, KG; Klee, EW; Kleinendorst, L; Ross, OA; Sullivan, AE; van Gerpen, JA; van Haelst, MM; Whitelaw, ML; Wierenga, KJ	1
Brozinick, JT; Carson, MW; Christopher, BA; Crown, SB; Foster, MW; Gersbach, CA; Gimeno, RE; Hammond, CD; Ilkayeva, O; Kajimura, S; McGarrah, RW; Moseley, MA; Muehlbauer, MJ; Newgard, CB; Page, S; Pickar-Oliver, A; van Vliet, S; Walejko, JM; White, PJ; Yoneshiro, T; Zhang, GF	1
Hu, X; Jin, H; Li, J; Shao, D; Shi, J; Yan, X	1
Alexander, CM; Baur, JA; Brinkman, JA; Cheng, EP; Finke, M; Flores, V; Green, CL; Haider, LR; Jang, C; Kasza, I; Konon, EN; Lamming, DW; Malecki, KC; Miller, BR; Murphy, ME; Nikodemova, M; Pak, HH; Quinn, WJ; Rabinowitz, JD; Richardson, NE; Rojas, JM; Sonsalla, M; Spicer, AB; Tomasiewicz, JL; Wakai, MH; Yang, SE; Yu, D	1
Cho, S; Park, KW; Yang, J	1
Assadi-Porter, FM; Butz, DE; Chiellini, G; Haviland, JA; Porter, WP; Reiland, H; Scanlan, TS; Tonelli, M; Zucchi, R	1
Hasan, AU; Hashimoto, T; Ishihara, N; Ishihara, Y; Kamitori, K; Kohno, M; Noma, T; Ohmori, K; Tokuda, M; Yamaguchi, F	1
Ahn, JH; Cha, BS; Choi, CS; Kang, ES; Kim, YW; Lee, BW; Lee, EY; Lee, HC; Oh, H	1
Corradi, L; Derosa, G; Fogari, R; Lazzari, P; Mugellini, A; Preti, P; Santoro, T; Zoppi, A	1
Djan, I; Djan, M; Plećas, A; Srdić, B; Stokić, E; Vapa, Lj	1
Bassols, J; Botas, P; Delgado, E; Fernández-Real, JM; Menéndez, JA; Moreno-Navarrete, JM; Ortega, FJ; Pardo, G; Ricart, W; Valdés, S; Vázquez-Martín, A	1
Cheng, M; Lindpaintner, K; Liu, L; Liu, X; Ma, L; Ma, X; Peng, Z; Ruan, X; Wang, B; Wang, S; Wang, X; Zhang, J	1
Brown, RE; Imran, SA; Wilkinson, M	1
Deedwania, PC; Egan, BM; Jialal, I; Ofili, EO; Purkayastha, D; Raij, L; Samuel, R; Sowers, JR; Zappe, DH	1
Rudolph, A; Weintraub, HS	1
Akhtari, S; Andalib, A; Curnew, G; Leclerc, JM; Rigal, R; Tardif, JC; Vaillancourt, M	1
Circelli, M; Cremonesi, G; Fogari, R; Mugellini, A	1
Matsuura, K; Mori, Y; Tanaka, T; Utsunomiya, K; Yokoyama, J	1
Borovecki, F; Curkovic, M; Dodig-Curkovic, K; Nikolac, M; Pivac, N; Skledar, M	1
Dralova, OV; Ermolaeva, AS; Maksimov, ML	1
Egan, BM; Purkayastha, D; Raij, L; Samuel, R; Sowers, JR; Zappe, DH	1
Han, G; Lieberman, K; Meyers, KE; Shi, V; Solar-Yohay, S	1
Biskupiak, J; Qian, C; Quah, R; Ram, CV; Ramaswamy, K; Russo, PA; Ryan, A	1
Clish, CB; Deik, AA; Fleischman, A; Gerszten, RE; Grinspoon, SK; McCarthy, MA; McCormack, SE; Mootha, VK; Shaham, O; Wang, TJ	1
Brozinick, JT; Grove, K; Hawkins, E; Hoang Bui, H; Kievit, P; Kuo, MS; Tan, B	1
Goto, SN; Mizuno, Y; Takagi, H; Umemoto, T; Yamamoto, H	1
Björntorp, P; Bouchard, C; Rosmond, R	1
Baier, LJ; Bogardus, C; Hanson, RL; Harper, I; Infante, AM; Kovacs, P; Tataranni, PA	1
Heist, K; Kontogianni, M; Mantzoros, CS; Melistas, L; Yiannakouris, N	1
Ambrosi, P; Andrejak, M; Drici, MD; Herpin, D; Pithois-Merli, I	1
Bönner, G; Heintz, D; Kandra, A; Khder, Y; Malacco, E; Ruilope, LM	1
Derosa, G; Fogari, E; Fogari, R; Lazzari, P; Mugellini, A; Preti, P; Rinaldi, A; Zoppi, A	1
Boschmann, M; Engeli, S; Jordan, J; Kreuzberg, U; Luft, FC; Sharma, AM; Weidinger, G	1
Hirata, Y; Hirono, Y; Sugiyama, T; Tateno, T; Tsuchiya, K; Yoshimoto, T	1
Adams, F; Boschmann, M; Engeli, S; Franke, G; Jordan, J; Klaua, S; Kreuzberg, U; Luft, FC; Scholze, J; Sharma, AM; Weidinger, G	1
Itoh, Y; Mori, Y; Tajima, N	1
Davidson, J; Koval, S; Lacourcière, Y; Sharma, AM	1
Horiuchi, M; Inaba, S; Iwai, M; Mogi, M; Tomono, Y	1
Boehm, TM; Bongiovanni, R; Glass, AR; Smith, CE	1
Groop, L; Klannemark, M; Orho, M	1
Albu, J; Allison, DB; Burn, P; Chin, W; Deng, N; Duprat, L; Fisher, SL; Franco, LS; Gu, W; Heymsfield, S; Kissebah, A; Kleyn, PW; Lee, J; Maruti, S; Nathan, J; Pi-Sunyer, FX; Tu, Z; Yagaloff, KA	1
Palou, A; Proenza, AM; Roca, P	1
Astrup, A; Bibby, BM; Buemann, B; Dalgaard, L; Pedersen, O; Schierning, B; Sørensen, T; Toubro, S	1
Dunseath, G; Luzio, SD; Owens, DR	1
Chaussain, JL; Georges, P; Job, JC; Olive, G	1
Herbertz, L; Langer, K; Schauder, P; Zavelberg, D	1
Fletcher, JM; Haggarty, P; Reeds, PJ; Wahle, KW	1
Owen, OE; Pozefsky, T; Sapir, DG; Walser, M	1
Briel, G; Gylfe, E; Hellman, B; Neuhoff, V	1
Gylfe, E	1
Genuth, SM	1
Hellerström, C; Schmidt, FH; Stork, H; Westman, S	1
Adibi, SA; Drash, AL	1
Adibi, SA	1
Bourges, HR; Farrish, GC; Gray, SJ; Ross, JR; Steiner, M	1
Farrish, GC; Gray, SJ; Steiner, M	1
Cahill, GF; Felig, P; Marliss, E	1
Drenick, EJ; Figueroa, WS; Swendseid, ME; Villalobos, J	1

Reviews

6 review(s) available for valine and Obesity

Article	Year
Branched-chain amino acids as a novel biomarker of metabolic disturbances in women with polycystic ovary syndrome - literature review. Ginekologia polska, 2022, Volume: 93, Issue:8 Topics: Amino Acids, Branched-Chain; Animals; Biomarkers; Diabetes Mellitus, Type 2; Female; Humans; Insulin Resistance; Isoleucine; Leucine; Obesity; Polycystic Ovary Syndrome; Prediabetic State; Valine	2022
Combination therapy for managing difficult-to-treat patients with stage 2 hypertension: focus on valsartan-based combinations. American journal of therapeutics, 2011, Volume: 18, Issue:6 Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Black or African American; Calcium Channel Blockers; Diuretics; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Obesity; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan	2011
Combination delapril/manidipine as antihypertensive therapy in high-risk patients. Clinical drug investigation, 2011, Volume: 31, Issue:7 Topics: Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Clinical Trials as Topic; Diabetes Complications; Dihydropyridines; Drug Combinations; Enalapril; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Indans; Irbesartan; Losartan; Nitrobenzenes; Obesity; Olmesartan Medoxomil; Piperazines; Ramipril; Tetrazoles; Valine; Valsartan	2011
[Hypertension, obesity, erectile dysfunction. What kind of drug to choose]. Kardiologiia, 2011, Volume: 51, Issue:7 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Erectile Dysfunction; Humans; Hypertension; Male; Obesity; Renin-Angiotensin System; Risk Factors; Tetrazoles; Valine; Valsartan	2011
Effects of telmisartan therapy on interleukin-6 and tumor necrosis factor-alpha levels: a meta-analysis of randomized controlled trials. Hypertension research : official journal of the Japanese Society of Hypertension, 2013, Volume: 36, Issue:4 Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Blood Pressure; Calcium Channel Blockers; Confidence Intervals; Cross-Over Studies; Double-Blind Method; Humans; Hypertension; Hypertension, Renal; Imidazoles; Interleukin-6; Obesity; Prospective Studies; Publication Bias; Randomized Controlled Trials as Topic; Stents; Telmisartan; Tetrazoles; Tumor Necrosis Factor-alpha; Valine; Valsartan	2013
[The best of clinical pharmacology in 2004]. Archives des maladies du coeur et des vaisseaux, 2005, Volume: 98 Spec No 1 Topics: Angina Pectoris; Angiotensin II Type 1 Receptor Blockers; Cardiovascular Diseases; Diabetes Complications; Humans; Obesity; Tetrazoles; Valine; Valsartan	2005

Trials

12 trial(s) available for valine and Obesity

Article	Year
Changes in Circulating Metabolites during Weight Loss and Weight Loss Maintenance in Relation to Cardiometabolic Risk. Nutrients, 2021, Nov-27, Volume: 13, Issue:12 Topics: Adult; Aged; Body Mass Index; Body Weight Maintenance; Caloric Restriction; Cardiometabolic Risk Factors; Cholesterol; Cholesterol, LDL; Female; Humans; Linear Models; Male; Middle Aged; Obesity; Phosphatidylcholines; Prospective Studies; Satiation; Sphingomyelins; Triglycerides; Valine; Weight Loss; Young Adult	2021
Effect of valsartan addition to amlodipine on insulin sensitivity in overweight-obese hypertensive patients. Internal medicine (Tokyo, Japan), 2008, Volume: 47, Issue:21 Topics: Adult; Aged; Amlodipine; Cross-Over Studies; Drug Therapy, Combination; Female; Humans; Hypertension; Insulin; Male; Middle Aged; Obesity; Overweight; Prospective Studies; Tetrazoles; Valine; Valsartan	2008
Angiotensin receptor blocker/diuretic combination preserves insulin responses in obese hypertensives. Journal of hypertension, 2010, Volume: 28, Issue:8 Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Blood Glucose; Blood Pressure; Body Mass Index; Calcium Channel Blockers; Diuretics; Drug Therapy, Combination; Female; Glucose Tolerance Test; Humans; Hydrochlorothiazide; Hypertension; Insulin; Male; Middle Aged; Obesity; Tetrazoles; Treatment Outcome; Valine; Valsartan	2010
Influence of telmisartan on insulin response after glucose loading in obese patients with hypertension: ARB trial of hypertension in obese patients with hyperinsulinemia assessed by oral glucose tolerance test (ATHLETE). Advances in therapy, 2011, Volume: 28, Issue:8 Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Glucose; Blood Pressure; Female; Glucose; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypertension; Insulin Resistance; Male; Obesity; Telmisartan; Tetrazoles; Valine; Valsartan	2011
Office and ambulatory blood pressure-lowering effects of combination valsartan/hydrochlorothiazide vs. hydrochlorothiazide-based therapy in obese, hypertensive patients. Journal of clinical hypertension (Greenwich, Conn.), 2011, Volume: 13, Issue:10 Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Comorbidity; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Obesity; Office Visits; Tetrazoles; Treatment Outcome; Valine; Valsartan	2011
The efficacy and safety of valsartan in obese and non-obese pediatric hypertensive patients. Journal of clinical hypertension (Greenwich, Conn.), 2011, Volume: 13, Issue:10 Topics: Adolescent; Antihypertensive Agents; Blood Pressure; Child; Comorbidity; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypertension; International Cooperation; Male; Obesity; Tetrazoles; Treatment Outcome; Valine; Valsartan	2011
Efficacy and tolerability of combination therapy with valsartan plus hydrochlorothiazide compared with amlodipine monotherapy in hypertensive patients with other cardiovascular risk factors: the VAST study. Clinical therapeutics, 2005, Volume: 27, Issue:5 Topics: Age Factors; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Cerebrovascular Disorders; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypercholesterolemia; Hypertension; Male; Middle Aged; Myocardial Infarction; Obesity; Risk Factors; Tetrazoles; Valine; Valsartan	2005
Comparison of the effects of valsartan and felodipine on plasma leptin and insulin sensitivity in hypertensive obese patients. Hypertension research : official journal of the Japanese Society of Hypertension, 2005, Volume: 28, Issue:3 Topics: Aged; Antihypertensive Agents; Felodipine; Female; Humans; Hypertension; Insulin Resistance; Leptin; Male; Middle Aged; Obesity; Tetrazoles; Treatment Outcome; Valine; Valsartan	2005
Hemodynamic and metabolic responses to valsartan and atenolol in obese hypertensive patients. Journal of hypertension, 2005, Volume: 23, Issue:12 Topics: Adrenergic beta-Antagonists; Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Atenolol; Blood Glucose; Blood Pressure; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Lipids; Male; Middle Aged; Obesity; Sodium Chloride Symporter Inhibitors; Tetrazoles; Valine; Valsartan	2005
The effect of oral glucose loads on tissue metabolism during angiotensin II receptor and beta-receptor blockade in obese hypertensive subjects. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2006, Volume: 38, Issue:5 Topics: Adipose Tissue; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Atenolol; Blood Glucose; Diabetes Mellitus, Type 2; Double-Blind Method; Ethanol; Fatty Acids, Nonesterified; Female; Glucose; Glucose Tolerance Test; Glycerol; Humans; Hypertension; Insulin; Kinetics; Lactic Acid; Lipids; Male; Metabolism; Middle Aged; Muscle, Skeletal; Obesity; Tetrazoles; Valine; Valsartan	2006
Telmisartan/hydrochlorothiazide versus valsartan/hydrochlorothiazide in obese hypertensive patients with type 2 diabetes: the SMOOTH study. Cardiovascular diabetology, 2007, Oct-02, Volume: 6 Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Diabetes Mellitus, Type 2; Diastole; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Male; Middle Aged; Obesity; Placebos; Single-Blind Method; Systole; Telmisartan; Tetrazoles; Valine; Valsartan	2007
Acute effects of valsartan on insulin sensitivity in obese, non-hypertensive subjects with and without type 2 diabetes. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2002, Volume: 34, Issue:5 Topics: Adolescent; Adult; Antihypertensive Agents; Cross-Over Studies; Diabetes Mellitus; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Obesity; Tetrazoles; Valine; Valsartan	2002

Other Studies

47 other study(ies) available for valine and Obesity

Article	Year
Detrimental effects of branched-chain amino acids in glucose tolerance can be attributed to valine induced glucotoxicity in skeletal muscle. Nutrition & diabetes, 2022, 04-13, Volume: 12, Issue:1 Topics: Amino Acids, Branched-Chain; Animals; Glucose; Insulin Resistance; Leucine; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Obesity; Valine	2022
Intervention with isoleucine or valine corrects hyperinsulinemia and reduces intrahepatic diacylglycerols, liver steatosis, and inflammation in Ldlr-/-.Leiden mice with manifest obesity-associated NASH. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2022, Volume: 36, Issue:8 Topics: Amino Acids, Branched-Chain; Animals; Diglycerides; Hyperinsulinism; Inflammation; Isoleucine; Liver; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Obesity; Valine	2022
Associations of serum amino acids with insulin resistance among people with and without overweight or obesity: A prospective study in Japan. Clinical nutrition (Edinburgh, Scotland), 2022, Volume: 41, Issue:8 Topics: Alanine; Animals; Humans; Insulin; Insulin Resistance; Isoleucine; Japan; Methionine; Obesity; Overweight; Prospective Studies; Thinness; Tyrosine; Valine	2022
Systematic analysis of relationships between plasma branched-chain amino acid concentrations and cardiometabolic parameters: an association and Mendelian randomization study. BMC medicine, 2022, 12-15, Volume: 20, Issue:1 Topics: Amino Acids, Branched-Chain; Atherosclerosis; Cross-Sectional Studies; Diabetes Mellitus; Humans; Isoleucine; Mendelian Randomization Analysis; Obesity; Valine	2022
Impaired Adipocyte SLC7A10 Promotes Lipid Storage in Association With Insulin Resistance and Altered BCAA Metabolism. The Journal of clinical endocrinology and metabolism, 2023, 08-18, Volume: 108, Issue:9 Topics: Adipocytes; Amino Acids; Amino Acids, Branched-Chain; Animals; Fatty Acids; Glucose; Humans; Insulin Resistance; Lipid Metabolism; Mice; Obesity; RNA, Messenger; Tandem Mass Spectrometry; Valine	2023
Functional Analysis of the SIM1 Variant p.G715V in 2 Patients With Obesity. The Journal of clinical endocrinology and metabolism, 2020, 01-01, Volume: 105, Issue:1 Topics: Adult; Amino Acid Substitution; Basic Helix-Loop-Helix Transcription Factors; Genetic Association Studies; Glutamic Acid; Humans; Male; Middle Aged; Mutation, Missense; Obesity; Prader-Willi Syndrome; Repressor Proteins; Valine	2020
Branched-chain α-ketoacids are preferentially reaminated and activate protein synthesis in the heart. Nature communications, 2021, 03-15, Volume: 12, Issue:1 Topics: Amino Acids, Branched-Chain; Animals; Heart; Hemiterpenes; Keto Acids; Male; Mice; Mice, Inbred C57BL; Mitochondria; Obesity; Rats; Valine	2021
The anti-obesity effects exerted by different fractions of Artemisia sphaerocephala Krasch polysaccharide in diet-induced obese mice. International journal of biological macromolecules, 2021, Jul-01, Volume: 182 Topics: Animals; Anti-Obesity Agents; Artemisia; Diet, High-Fat; Gastrointestinal Microbiome; Isoleucine; Leucine; Liver; Male; Mice; Mice, Inbred C57BL; Nitrogen; Obesity; Plant Extracts; Polysaccharides; Valine	2021
The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine. Cell metabolism, 2021, 05-04, Volume: 33, Issue:5 Topics: Adipose Tissue, White; Amino Acids, Branched-Chain; Animals; Body Mass Index; Diet; Energy Metabolism; Fibroblast Growth Factors; Humans; Isoleucine; Liver; Male; Mechanistic Target of Rapamycin Complex 1; Mice; Mice, Inbred C57BL; Mice, Knockout; Obesity; Protein Serine-Threonine Kinases; Uncoupling Protein 1; Valine	2021
Inhibition of the CD36 receptor reduces visceral fat accumulation and improves insulin resistance in obese mice carrying the BDNF- The Journal of biological chemistry, 2018, 08-24, Volume: 293, Issue:34 Topics: Animals; Benzofurans; Brain-Derived Neurotrophic Factor; CD36 Antigens; Cell Differentiation; Diet, High-Fat; Insulin Resistance; Intra-Abdominal Fat; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Obese; Mutation; Obesity; Valine	2018
NMR-based metabolomics and breath studies show lipid and protein catabolism during low dose chronic T(1)AM treatment. Obesity (Silver Spring, Md.), 2013, Volume: 21, Issue:12 Topics: 3-Hydroxybutyric Acid; Animals; Body Weight; Breath Tests; Dietary Proteins; Dose-Response Relationship, Drug; Female; Glycine; Lipolysis; Magnetic Resonance Spectroscopy; Metabolomics; Mice; Obesity; Thyronines; Valine; Weight Loss	2013
Valsartan ameliorates the constitutive adipokine expression pattern in mature adipocytes: a role for inverse agonism of the angiotensin II type 1 receptor in obesity. Hypertension research : official journal of the Japanese Society of Hypertension, 2014, Volume: 37, Issue:7 Topics: 3T3-L1 Cells; Active Transport, Cell Nucleus; Adipocytes; Adipokines; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Chlorocebus aethiops; COS Cells; Drug Inverse Agonism; Interleukin-6; Mice; NF-kappa B; Obesity; PPAR gamma; Receptor, Angiotensin, Type 1; Tetrazoles; Valine; Valsartan	2014
Anti-obesity effects of KR-66195, a synthetic DPP-IV inhibitor, in diet-induced obese mice and obese-diabetic ob/ob mice. Metabolism: clinical and experimental, 2014, Volume: 63, Issue:6 Topics: Animals; Anti-Obesity Agents; Blood Glucose; Body Composition; Diabetes Mellitus; Diet, High-Fat; Dipeptidyl Peptidase 4; Eating; Energy Metabolism; Enzyme Inhibitors; Female; Glucagon-Like Peptide 1; Glucose Tolerance Test; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Random Allocation; Thiazolidines; Treatment Outcome; Valine; Weight Gain	2014
Polymorphism Val103Ile of the melanocortin-4 receptor gene in the Serbian population. Molecular biology reports, 2010, Volume: 37, Issue:1 Topics: Adult; Amino Acid Substitution; Female; Heterozygote; Homozygote; Humans; Isoleucine; Male; Obesity; Polymorphism, Single Nucleotide; Receptor, Melanocortin, Type 4; Serbia; Valine	2010
Val1483Ile in FASN gene is linked to central obesity and insulin sensitivity in adult white men. Obesity (Silver Spring, Md.), 2009, Volume: 17, Issue:9 Topics: Adipose Tissue; Adiposity; Adult; Age Factors; Blood Glucose; Blood Pressure; Body Mass Index; Case-Control Studies; Down-Regulation; Fatty Acid Synthase, Type I; Female; Gene Frequency; Genetic Predisposition to Disease; Humans; Insulin Resistance; Isoleucine; Male; Middle Aged; Obesity; Phenotype; Polymorphism, Single Nucleotide; Risk Factors; Sex Factors; Time Factors; Valine; Waist-Hip Ratio; Weight Gain	2009
TAQIB and I405V polymorphisms of CETP are moderately associated with obesity risk in the Chinese adult population. Acta diabetologica, 2010, Volume: 47, Issue:3 Topics: Adult; Amino Acid Substitution; Asian People; Case-Control Studies; Cholesterol Ester Transfer Proteins; Deoxyribonucleases, Type II Site-Specific; Female; Genetic Predisposition to Disease; Genetics, Population; Humans; Isoleucine; Male; Middle Aged; Obesity; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Risk; Valine	2010
Tissue-specific effects of valsartan on rstn and fiaf gene expression in the ob/ob mouse. Diabetes & vascular disease research, 2010, Volume: 7, Issue:3 Topics: Angiopoietin-Like Protein 4; Angiopoietins; Angiotensin II Type 1 Receptor Blockers; Animals; Cerebral Cortex; Diabetes Mellitus; Disease Models, Animal; Gene Expression Regulation; Hypothalamus; Intra-Abdominal Fat; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Pituitary Gland; Resistin; RNA, Messenger; Subcutaneous Fat; Tetrazoles; Time Factors; Valine; Valsartan	2010
Determinants of masked hypertension in hypertensive patients treated in a primary care setting. Internal medicine journal, 2012, Volume: 42, Issue:3 Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Cardiovascular Diseases; Comorbidity; Diabetes Complications; Drug Therapy, Combination; Dyslipidemias; Female; Heart Failure; Humans; Hydrochlorothiazide; Hypertension; Male; Masked Hypertension; Middle Aged; Obesity; Prevalence; Primary Health Care; Quebec; Risk; Tetrazoles; Valine; Valsartan; White Coat Hypertension	2012
Association between brain-derived neurotrophic factor Val66Met and obesity in children and adolescents. Progress in neuro-psychopharmacology & biological psychiatry, 2012, Jan-10, Volume: 36, Issue:1 Topics: Adolescent; Alleles; Amino Acid Substitution; Body Mass Index; Brain-Derived Neurotrophic Factor; Child; Child, Preschool; Croatia; Eating; Energy Metabolism; Female; Genetic Association Studies; Humans; Male; Methionine; Obesity; Polymorphism, Genetic; Valine	2012
Blood pressure outcomes in patients receiving angiotensin II receptor blockers in primary care: a comparative effectiveness analysis from electronic medical record data. Journal of clinical hypertension (Greenwich, Conn.), 2011, Volume: 13, Issue:11 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Biphenyl Compounds; Black or African American; Blood Pressure; Diabetes Mellitus; Electronic Health Records; Female; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Male; Middle Aged; Obesity; Primary Health Care; Retrospective Studies; Tetrazoles; Treatment Outcome; Valine; Valsartan; White People; Young Adult	2011
Circulating branched-chain amino acid concentrations are associated with obesity and future insulin resistance in children and adolescents. Pediatric obesity, 2013, Volume: 8, Issue:1 Topics: Adolescent; Amino Acids, Branched-Chain; Biomarkers; Blood Glucose; Body Mass Index; Child; Child Nutrition Disorders; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Fasting; Female; Humans; Insulin; Insulin Resistance; Insulin Secretion; Isoleucine; Leucine; Longitudinal Studies; Male; Massachusetts; Obesity; Predictive Value of Tests; Valine	2013
Plasma sphingolipids are biomarkers of metabolic syndrome in non-human primates maintained on a Western-style diet. International journal of obesity (2005), 2013, Volume: 37, Issue:8 Topics: Animals; Biomarkers; Ceramides; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Disease Progression; Fructose; Insulin Resistance; Macaca mulatta; Male; Metabolic Syndrome; Obesity; Risk Factors; Serine C-Palmitoyltransferase; Sphingolipids; Valine	2013
Lack of association between the uncoupling protein-2 Ala55Val gene polymorphism and phenotypic features of the Metabolic Syndrome. Biochimica et biophysica acta, 2002, Nov-20, Volume: 1588, Issue:2 Topics: Alanine; Alleles; Blood Glucose; Blood Pressure; Humans; Insulin; Ion Channels; Male; Membrane Transport Proteins; Metabolic Syndrome; Middle Aged; Mitochondrial Proteins; Obesity; Phenotype; Proteins; Sweden; Uncoupling Protein 2; Valine	2002
A novel missense substitution (Val1483Ile) in the fatty acid synthase gene (FAS) is associated with percentage of body fat and substrate oxidation rates in nondiabetic Pima Indians. Diabetes, 2004, Volume: 53, Issue:7 Topics: Adipose Tissue; Adult; Alleles; Carbohydrate Metabolism; Fatty Acid Synthases; Gene Frequency; Genetic Variation; Humans; Indians, North American; Isoleucine; Mutation, Missense; Obesity; Oxidation-Reduction; Valine	2004
The Val81 missense mutation of the melanocortin 3 receptor gene, but not the 1908c/T nucleotide polymorphism in lamin A/C gene, is associated with hyperleptinemia and hyperinsulinemia in obese Greek caucasians. Journal of endocrinological investigation, 2004, Volume: 27, Issue:8 Topics: Adult; Amino Acid Substitution; Body Composition; Body Mass Index; DNA; Female; Gene Frequency; Greece; Humans; Hyperinsulinism; Insulin; Lamin Type A; Leptin; Male; Mutation, Missense; Obesity; Polymorphism, Genetic; Receptor, Melanocortin, Type 3; Regression Analysis; Valine	2004
Angiotensin II induces monocyte chemoattractant protein-1 expression via a nuclear factor-kappaB-dependent pathway in rat preadipocytes. American journal of physiology. Endocrinology and metabolism, 2006, Volume: 291, Issue:4 Topics: Adipocytes; Adipose Tissue; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Cell Differentiation; Chemokine CCL2; Humans; Male; NF-kappa B; Nitriles; Obesity; Promoter Regions, Genetic; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfones; Tetrazoles; Thiocarbamates; Transcription, Genetic; Valine; Valsartan	2006
Angiotensin II receptor blockers downsize adipocytes in spontaneously type 2 diabetic rats with visceral fat obesity. American journal of hypertension, 2007, Volume: 20, Issue:4 Topics: Adipocytes; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blood Glucose; Calcium Channel Blockers; Cell Size; Diabetes Mellitus, Type 2; Disease Models, Animal; Insulin; Intra-Abdominal Fat; Male; Obesity; PPAR gamma; Random Allocation; Rats; Rats, Long-Evans; Telmisartan; Tetrazoles; Valine; Valsartan	2007
Blockade of AT1 receptor improves adipocyte differentiation in atherosclerotic and diabetic models. American journal of hypertension, 2008, Volume: 21, Issue:2 Topics: Adipocytes, White; Adiponectin; Angiotensin II Type 1 Receptor Blockers; Animals; Apolipoproteins E; Atherosclerosis; Cell Differentiation; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Disease Models, Animal; Gene Deletion; Gene Expression; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Obesity; PPAR gamma; Receptor, Angiotensin, Type 1; Tetrazoles; Valine; Valsartan	2008
Normal valine disposal in obese subjects with impaired glucose disposal: evidence for selective insulin resistance. Metabolism: clinical and experimental, 1981, Volume: 30, Issue:6 Topics: Blood Glucose; Female; Glucose; Humans; Insulin; Insulin Resistance; Male; Metabolic Clearance Rate; Obesity; Valine	1981
No relationship between identified variants in the uncoupling protein 2 gene and energy expenditure. European journal of endocrinology, 1998, Volume: 139, Issue:2 Topics: Aged; Alanine; Amino Acid Substitution; Energy Metabolism; Exons; Female; Genetic Variation; Genotype; Humans; Introns; Ion Channels; Male; Membrane Transport Proteins; Middle Aged; Mitochondrial Proteins; Molecular Sequence Data; Obesity; Polymorphism, Single-Stranded Conformational; Proteins; Syndrome; Uncoupling Protein 2; Valine	1998
Identification and functional analysis of novel human melanocortin-4 receptor variants. Diabetes, 1999, Volume: 48, Issue:3 Topics: Adolescent; Adult; Amino Acid Substitution; Animals; Body Mass Index; Cloning, Molecular; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Genetic Predisposition to Disease; Genetic Variation; Genotype; Humans; Isoleucine; Male; Methionine; Mice; Middle Aged; Obesity; Pedigree; Polymorphism, Single-Stranded Conformational; Receptor, Melanocortin, Type 4; Receptors, Peptide; Recombinant Proteins; Threonine; Valine	1999
Sex differences in the effect of obesity on human plasma tryptophan/large neutral amino acid ratio. Annals of nutrition & metabolism, 1999, Volume: 43, Issue:3 Topics: Amino Acids; Body Mass Index; Female; Humans; Leucine; Male; Obesity; Phenylalanine; Sex Characteristics; Tryptophan; Tyrosine; Valine	1999
The association between the val/ala-55 polymorphism of the uncoupling protein 2 gene and exercise efficiency. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 2001, Volume: 25, Issue:4 Topics: Adult; Alanine; Calorimetry, Indirect; Energy Metabolism; Exercise; Exercise Test; Female; Genotype; Homozygote; Humans; Linkage Disequilibrium; Male; Obesity; Oxygen Consumption; Polymorphism, Genetic; Saccharomyces cerevisiae Proteins; Trans-Activators; Valine	2001
Effect of 24 hour fast in obese children. Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1976, Sep-30, Volume: 25, Issue:8 Topics: Adolescent; Alanine; Blood Glucose; Child; Fasting; Fatty Acids, Nonesterified; Female; Glucagon; Growth Hormone; Humans; Insulin; Isoleucine; Ketone Bodies; Leucine; Male; Obesity; Valine	1976
Sex-specific differences in plasma branched-chain keto acid levels in obesity. The American journal of clinical nutrition, 1987, Volume: 46, Issue:1 Topics: Blood Glucose; Body Composition; Female; Hemiterpenes; Humans; Insulin; Insulin Resistance; Isoleucine; Keto Acids; Leucine; Male; Middle Aged; Obesity; Sex Characteristics; Valine	1987
The fate of 14C derived from radioactively labelled dietary precursors in young rats of the Zucker strain (Fa/- and fa/fa). The Biochemical journal, 1986, Apr-15, Volume: 235, Issue:2 Topics: Animals; Carbon Radioisotopes; Glucose; Lactates; Lactic Acid; Leucine; Obesity; Palmitic Acid; Palmitic Acids; Rats; Rats, Zucker; Valine	1986
Nitrogen sparing induced by a mixture of essential amino acids given chiefly as their keto-analogues during prolonged starvation in obese subjects. The Journal of clinical investigation, 1974, Volume: 54, Issue:4 Topics: Amino Acids; Female; Humans; Infusions, Parenteral; Isoleucine; Keto Acids; Leucine; Methionine; Nitrogen; Obesity; Phenylalanine; Starvation; Urea; Valine	1974
Microdetermination of free amino acids in pancreatic islets isolated from obese-hyperglycemic mice. Acta physiologica Scandinavica, 1972, Volume: 84, Issue:2 Topics: Amino Acids; Animals; Binding Sites; Carbon Isotopes; Chromatography, Thin Layer; Dansyl Compounds; Fatty Acids, Nonesterified; Hyperglycemia; Islets of Langerhans; Leucine; Mice; Obesity; Taurine; Valine	1972
Changes of free amino acids in pancreatic beta-cells after starvation and substrate deprivation. Acta endocrinologica, 1974, Volume: 75, Issue:1 Topics: Alanine; Amino Acids; Aminobutyrates; Animals; Aspartic Acid; Carbon Radioisotopes; Chromatography, Thin Layer; Dansyl Compounds; Diabetes Mellitus; Fasting; Female; Freeze Drying; Glutamates; Glycine; Islets of Langerhans; Leucine; Lysine; Mice; Obesity; Ornithine; Phenylalanine; Proline; Taurine; Tritium; Valine	1974
Effects of oral alanine administration in fasting obese subjects. Metabolism: clinical and experimental, 1973, Volume: 22, Issue:7 Topics: Administration, Oral; Adult; Alanine; Blood Glucose; Female; Gluconeogenesis; Humans; Hydroxybutyrates; Insulin; Isoleucine; Leucine; Male; Middle Aged; Nitrogen; Obesity; Phosphorus; Potassium; Urea; Uric Acid; Valine	1973
[Effect of blood sugar decreasing sulfonylureas on the in vitro metabolism of glucose and amino acids in the beta-cells of the pancreas in mice]. Arzneimittel-Forschung, 1969, Volume: 19, Issue:8 Topics: Alanine; Amino Acids; Animals; Arginine; Carbon Isotopes; Depression, Chemical; Female; Glucose; Hyperglycemia; Hypoglycemic Agents; In Vitro Techniques; Insulin; Islets of Langerhans; Leucine; Male; Mice; Obesity; Oxidation-Reduction; Oxygen Consumption; Pancreas; Stimulation, Chemical; Tolbutamide; Urea; Valine	1969
Hormone and amino acid levels in altered nutritional states. The Journal of laboratory and clinical medicine, 1970, Volume: 76, Issue:5 Topics: Adult; Alanine; Amino Acids; Aminobutyrates; Female; Growth Hormone; Humans; Insulin; Isoleucine; Leucine; Male; Nutritional Physiological Phenomena; Obesity; Protein Deficiency; Starvation; Valine	1970
Alteration in the urinary excretion rate of amino acids and nitrogen by dietary means in obese and normal human subjects. The Journal of laboratory and clinical medicine, 1971, Volume: 77, Issue:2 Topics: Adult; Alanine; Amino Acids; Creatinine; Female; Humans; Isoleucine; Leucine; Male; Nitrogen; Obesity; Protein Deficiency; Renal Aminoacidurias; Starvation; Taurine; Urea; Valine	1971
Intestinal uptake of valine in obesity. The American journal of the medical sciences, 1969, Volume: 257, Issue:4 Topics: Adaptation, Psychological; Adult; Biopsy; Carbon Isotopes; DNA; Female; Humans; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Kinetics; Male; Middle Aged; Obesity; Valine	1969
Intestinal uptake of valine in calorie and protein deprivation. The American journal of clinical nutrition, 1969, Volume: 22, Issue:7 Topics: Adult; Biopsy; Blood Glucose; Blood Urea Nitrogen; Body Weight; Carbon Isotopes; Cholesterol; Creatinine; Fatty Acids; Fatty Acids, Nonesterified; Female; Humans; Intestinal Absorption; Intestinal Mucosa; Jejunum; Male; Middle Aged; Obesity; Protein Deficiency; Starvation; Time Factors; Triglycerides; Uric Acid; Valine	1969
Plasma amino acid levels and insulin secretion in obesity. The New England journal of medicine, 1969, Oct-09, Volume: 281, Issue:15 Topics: Adolescent; Adult; Amino Acids; Blood Glucose; Fasting; Feedback; Female; Glucose; Glycine; Humans; Insulin; Insulin Resistance; Insulin Secretion; Isoleucine; Leucine; Male; Middle Aged; Obesity; Pancreas; Phenylalanine; Tyrosine; Valine	1969
The effects of test doses of leucine, isoleucine or valine on plasma amino acid levels. The unique effect of leucine. The American journal of clinical nutrition, 1965, Volume: 17, Issue:5 Topics: Amino Acids; Blood; Fasting; Humans; Isoleucine; Leucine; Male; Obesity; Valine	1965