Compounds > valine

valine and Neoplasm Metastasis

valine has been researched along with Neoplasm Metastasis in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19903 (25.00)18.7374
1990's0 (0.00)18.2507
2000's2 (16.67)29.6817
2010's6 (50.00)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Chen, Z; Qin, Z; Su, D; Wang, X1
Chen, L; Cheung, TT; Lee, TK; Lo, CM; Olson, P; Wang, XQ; Wu, CX; Xu, A; Zhang, CC1
Aymerich, M; Campo, E; Colomer, D; López-Guerra, M; López-Otín, C; Matas-Céspedes, A; Montraveta, A; Pérez-Galán, P; Roldán, J; Rosich, L; Roué, G; Villamor, N; Xargay-Torrent, S1
Aktan, G; Amonkar, MM; Arance, A; Bondarenko, I; Casey, M; Chiarion-Sileni, V; de Braud, F; DeMarini, DJ; Flaherty, KT; Garbe, C; Gogas, H; Grob, JJ; Irani, JG; Larkin, J; Lebbe, C; Levchenko, E; Long, GV; Mandalà, M; Millward, M; Nathan, P; Ribas, A; Robert, C; Schadendorf, D; Stroyakovskiy, D1
Ciardiello, F; De Luca, A; Morgillo, F; Normanno, N; Tejpar, S; Van Cutsem, E1
Coral, S; Fratta, E; Maio, M; Parisi, G; Sigalotti, L1
Christensen, JG; Lappin, PB; Lee, NV; Lira, ME; Ozeck, M; Painter, CL; Pavlicek, A; Qiu, M; Rejto, PA; Smeal, T; Wong, A; Yan, Z; Zhang, CC; Zhang, Q; Zheng, X; Zong, Q1
Clements, A; Kefford, RF; Klein, O; Long, GV; Menzies, AM; O'Toole, S1
FIELD, JB1
Capellà, G; Casanova, I; Cascante, M; Céspedes, MV; Guerrero, S; Mangues, R; Marcuello, E; Parreño, M; Pavón, MA; Sancho, FJ; Trias, M1
Bojan, O; Kiricuta, I1
Bojan, O; Mustea, I; Preda, N1

Reviews

1 review(s) available for valine and Neoplasm Metastasis

ArticleYear
Implications for KRAS status and EGFR-targeted therapies in metastatic CRC.
    Nature reviews. Clinical oncology, 2009, Volume: 6, Issue:9

    Topics: Amino Acid Sequence; Amino Acid Substitution; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Aspartic Acid; Base Sequence; Biomarkers, Tumor; Cetuximab; Codon; Colorectal Neoplasms; Drug Resistance, Neoplasm; ErbB Receptors; Exons; Genes, ras; Humans; Molecular Sequence Data; Neoplasm Metastasis; Panitumumab; Patient Selection; Point Mutation; ras Proteins; Signal Transduction; Valine

2009

Trials

1 trial(s) available for valine and Neoplasm Metastasis

ArticleYear
Health-related quality of life impact in a randomised phase III study of the combination of dabrafenib and trametinib versus dabrafenib monotherapy in patients with BRAF V600 metastatic melanoma.
    European journal of cancer (Oxford, England : 1990), 2015, Volume: 51, Issue:7

    Topics: Amino Acid Substitution; Antineoplastic Combined Chemotherapy Protocols; Health Status; Humans; Imidazoles; Melanoma; Neoplasm Metastasis; Oximes; Pain Measurement; Proto-Oncogene Mas; Proto-Oncogene Proteins B-raf; Pyridones; Pyrimidinones; Quality of Life; Skin Neoplasms; Valine

2015

Other Studies

10 other study(ies) available for valine and Neoplasm Metastasis

ArticleYear
Identification of FOXN4 as a tumor suppressor of breast carcinogenesis via the activation of TP53 and deactivation of Notch signaling.
    Gene, 2020, 01-05, Volume: 722

    Topics: Adaptor Proteins, Signal Transducing; Adult; Animals; Breast Neoplasms; Calcium-Binding Proteins; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Female; Forkhead Transcription Factors; Humans; Intercellular Signaling Peptides and Proteins; Mammary Neoplasms, Experimental; Mice; Neoplasm Metastasis; Prognosis; Receptors, Notch; Signal Transduction; Tetrahydronaphthalenes; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Valine

2020
Notch Inhibitor PF-03084014 Inhibits Hepatocellular Carcinoma Growth and Metastasis via Suppression of Cancer Stemness due to Reduced Activation of Notch1-Stat3.
    Molecular cancer therapeutics, 2017, Volume: 16, Issue:8

    Topics: Antineoplastic Agents; Carcinogenesis; Carcinoma, Hepatocellular; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell Self Renewal; Humans; Liver Neoplasms; Neoplasm Metastasis; Neoplastic Stem Cells; Receptor, Notch1; Spheroids, Cellular; STAT3 Transcription Factor; Tetrahydronaphthalenes; Valine

2017
The γ-secretase inhibitor PF-03084014 combined with fludarabine antagonizes migration, invasion and angiogenesis in NOTCH1-mutated CLL cells.
    Leukemia, 2015, Volume: 29, Issue:1

    Topics: Aged; Amyloid Precursor Protein Secretases; Enzyme Inhibitors; Female; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Middle Aged; Mutation; Neoplasm Invasiveness; Neoplasm Metastasis; Neovascularization, Pathologic; Receptor, Notch1; Tetrahydronaphthalenes; Tumor Cells, Cultured; Valine; Vidarabine

2015
Stability of BRAF V600E mutation in metastatic melanoma: new insights for therapeutic success?
    British journal of cancer, 2011, Jul-12, Volume: 105, Issue:2

    Topics: Amino Acid Substitution; Disease Progression; Glutamic Acid; Humans; Melanoma; Mutation, Missense; Neoplasm Metastasis; Prognosis; Proto-Oncogene Proteins B-raf; Selection, Genetic; Skin Neoplasms; Treatment Outcome; Valine

2011
Biomarker and pharmacologic evaluation of the γ-secretase inhibitor PF-03084014 in breast cancer models.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Sep-15, Volume: 18, Issue:18

    Topics: Amyloid Precursor Protein Secretases; Antineoplastic Agents; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Cluster Analysis; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Human Umbilical Vein Endothelial Cells; Humans; Neoplasm Metastasis; Receptors, Notch; Signal Transduction; Tetrahydronaphthalenes; Valine; Xenograft Model Antitumor Assays

2012
BRAF inhibitor activity in V600R metastatic melanoma.
    European journal of cancer (Oxford, England : 1990), 2013, Volume: 49, Issue:5

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Antineoplastic Agents; Arginine; Compassionate Use Trials; Female; Humans; Imidazoles; Male; Melanoma; Middle Aged; Mutation, Missense; Neoplasm Metastasis; Oximes; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Skin Neoplasms; Valine; Young Adult

2013
CLINICAL AND BIOCHEMICAL STUDIES IN PATIENTS WITH FUNCTIONING ISLET CELL TUMORS.
    The American journal of medicine, 1964, Volume: 36

    Topics: Adenoma, Islet Cell; Amino Acids; Biochemical Phenomena; Biochemistry; Biomedical Research; Carbohydrate Metabolism; Glucose; Glucose Tolerance Test; Glutarates; Humans; Hypoglycemia; Insulin; Isoleucine; Leucine; Liver Neoplasms; Neoplasm Metastasis; Pancreatic Neoplasms; Research; Valine

1964
K-ras Asp12 mutant neither interacts with Raf, nor signals through Erk and is less tumorigenic than K-ras Val12.
    Carcinogenesis, 2006, Volume: 27, Issue:11

    Topics: Animals; Apoptosis; Aspartic Acid; Extracellular Signal-Regulated MAP Kinases; Male; Mice; Mice, Nude; Mutation; Neoplasm Metastasis; NIH 3T3 Cells; Oncogene Protein p21(ras); Protein Binding; Proto-Oncogene Proteins c-raf; Signal Transduction; Valine

2006
Differences in uptake of aminoacids by patients with various forms of cancer.
    Neoplasma, 1978, Volume: 25, Issue:5

    Topics: Amino Acids; Female; Humans; Lysine; Male; Neoplasm Metastasis; Neoplasms; Valine

1978
[Modification of some free amino acids in the serum of cancer patients under the influence of glucose on tumoral metabolism].
    Clinica chimica acta; international journal of clinical chemistry, 1969, Volume: 23, Issue:2

    Topics: Alanine; Amino Acids; Breast Neoplasms; Chromatography, Paper; Dietary Carbohydrates; Dietary Proteins; Female; Gastrointestinal Neoplasms; Glucose; Glycolysis; Leucine; Lung Neoplasms; Lysine; Neoplasm Metastasis; Perfusion; Stimulation, Chemical; Uterine Neoplasms; Valine

1969