valine has been researched along with Insulin Sensitivity in 72 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 5 (6.94) | 18.7374 |
1990's | 5 (6.94) | 18.2507 |
2000's | 17 (23.61) | 29.6817 |
2010's | 35 (48.61) | 24.3611 |
2020's | 10 (13.89) | 2.80 |
Authors | Studies |
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Goh, HJ; Goh, JP; Govindharajulu, P; Henry, CJ; Leow, MK; Michael, N; Sadananthan, SA; Sun, L; Velan, SS; Verma, S | 1 |
Bishop, CA; Grune, T; Henkel, J; Henning, T; Klaus, S; Machate, T; Püschel, G; Weber, D; Weitkunat, K | 1 |
Chen, S; Eguchi, M; Fukunaga, A; Kabe, I; Kochi, T; Miki, T; Mizoue, T; Nanri, A | 1 |
Lenart-Lipinska, M; Matyjaszek-Matuszek, B; Szmygin, H; Szydelko, J; Wozniak, S | 1 |
Bi, Y; Chen, Y; Kong, L; Li, M; Lu, J; Ning, G; Wang, T; Wang, W; Wang, Y; Xu, M; Xu, Y; Ye, C; Zhao, Z; Zheng, J | 1 |
Alvarez, M; André Drevon, C; Birkeland, KI; Bjune, MS; Claussnitzer, M; Dankel, SN; Heinonen, S; Jersin, RÅ; Lee-Ødegård, S; McCann, A; Mellgren, G; Muniandy, M; Pajukanta, P; Pietiläinen, KH; Skartveit, L; Sri Priyanka Tallapragada, D | 1 |
Choi, HJ; Jeon, HJ; Kim, BJ; Kim, JM; Kim, YJ; Lee, HS; Oh, T; Yu, HY; Yun, JH | 1 |
Abdel Moneim, A; Mabrouk, D; Mahmoud, B; Suleiman, HA; Zaky, MY | 1 |
Johnson, MA; Lyon, ES; Rivera, ME; Sunderland, KL; Vaughan, RA | 1 |
Altıntaş, E; Ateş, F; Özdoğan, O; Sezgin, O; Üçbilek, E; Yaraş, S | 1 |
Alizadeh, A; Hafezi, M; Hajitarkhani, S; Moini, A; Shahhoseini, M | 1 |
Chen, SC; Chuang, WL; Dai, CY; Hsieh, MH; Huang, CF; Huang, CI; Huang, JF; Liang, PC; Lin, YH; Lin, ZY; Yang, JF; Yeh, ML; Yu, ML | 1 |
He, T; Ma, X; Nie, C; Zhang, G; Zhang, W | 1 |
Al-Majdoub, M; Ali, A; Carstensen, B; Ridderstråle, M; Safai, N; Spégel, P; Suvitaival, T; Vestergaard, H | 1 |
Cho, S; Park, KW; Yang, J | 1 |
Auriola, S; Giacco, R; Hanhineva, K; Jokkala, J; Kärkkäinen, O; Koistinen, V; Kolehmainen, M; Lankinen, MA; Lehtonen, M; Leppänen, J; Micard, V; Mykkänen, H; Poutanen, K; Riccardi, G; Rivellese, AAA; Rosa-Sibakov, N; Schwab, U; Uusitupa, M; Vitale, M | 1 |
Kuusisto, J; Laakso, M; Smith, U; Stancáková, A; Vangipurapu, J | 1 |
El-Bassossy, HM; El-Fawal, R; Fahmy, A; Watson, ML | 1 |
Cong, XD; Dai, DZ; Dai, Y; Shi, FH; Wu, Y; Zhang, YM | 1 |
Choi, H; Han, SH; Koh, KK; Lee, K; Lee, Y; Lim, S; Oh, PC; Quon, MJ; Sakuma, I; Shin, EK | 1 |
Araki, E; Goto, R; Igata, M; Kawasaki, S; Kawashima, J; Kitano, S; Kondo, T; Matsumura, T; Matsuyama, R; Miyagawa, K; Motoshima, H; Ono, K | 1 |
Chen, S; Deng, J; Du, Y; Guo, F; Guo, Y; Li, K; Sheng, H; Xiao, F; Yu, J; Zhu, J | 1 |
Choovichian, P; Leelasiri, K; Satirapoj, B; Supasyndh, O | 1 |
Kim, SH; Lee, JH; Park, JY; Park, S | 1 |
Arrieta-Cruz, I; Gutiérrez-Juárez, R; Su, Y | 1 |
Bao, Y; Chen, T; Hu, C; Huang, F; Jia, W; Ma, X; Ni, Y; Rajani, C; Zhao, A; Zheng, X | 1 |
Civantos, E; Egido, J; Mas, S; Peiró, C; Ruiz-Ortega, M; Sánchez, MS; Vázquez, C; Zhenyukh, O | 1 |
Kohno, N; Nakanishi, S; Nakashima, R; Nojima, H; Ohishi, W; Watanabe, H; Yamane, K; Yoneda, M | 1 |
Bergmann, A; Bornstein, SR; Fischer, S; Grässler, J; Li, J; Reimann, M; Schulze, J; Schwarz, PE; Selisko, T | 1 |
Chen, YH; Chen, YY; Qi, CJ; Yuan, L | 1 |
Bassols, J; Botas, P; Delgado, E; Fernández-Real, JM; Menéndez, JA; Moreno-Navarrete, JM; Ortega, FJ; Pardo, G; Ricart, W; Valdés, S; Vázquez-Martín, A | 1 |
Frank, H; Heemann, U; Pscherer, S | 1 |
Carter, JD; Cole, BK; Keller, SR; Nadler, JL; Nunemaker, CS; Wu, R | 1 |
Kondo, K; Nomura, Y; Oiso, Y; Ozaki, N; Sobajima, H | 1 |
Kazawa, T; Kuroki, N; Kuwabara, M; Maruki, T; Odagaki, Y; Toyoshima, R; Yamashita, H; Yoda, H | 1 |
Blaak, EE; Diamant, M; Goossens, GH; Hermans, MM; Moors, CC; van der Zijl, NJ | 1 |
Jin, D; Miyazaki, M; Takai, S | 1 |
Matsuura, K; Mori, Y; Tanaka, T; Utsunomiya, K; Yokoyama, J | 1 |
Blaak, EE; Diamant, M; Goossens, GH; Ijzerman, RG; Moors, CC; Serné, EH; van der Zijl, NJ | 1 |
de Leeuw, PW | 1 |
Eringa, EC | 1 |
Akazawa, H; Asano, T; Fujishiro, M; Fukushima, T; Iwashita, M; Kamata, H; Kikuchi, T; Komuro, I; Kumamoto, S; Kurihara, H; Kushiyama, A; Nakatsu, Y; Nishimura, F; Ohno, H; Sakoda, H; Tsuchiya, Y | 1 |
Peng, XD; Yang, ZH | 1 |
Horiguchi, CS; Makino, H; Miyoshi, T; Murakami, K; Nakamura, Y; Ogawa, D; Sasaki, M; Uchida, HA; Wada, J | 1 |
Ando, H; Fujimura, A; Hosohata, K; Saito, T; Ushijima, K | 1 |
Clish, CB; Deik, AA; Fleischman, A; Gerszten, RE; Grinspoon, SK; McCarthy, MA; McCormack, SE; Mootha, VK; Shaham, O; Wang, TJ | 1 |
Ala-Korpela, M; Kähönen, M; Kangas, AJ; Lehtimäki, T; Raitakari, OT; Rönnemaa, T; Soininen, P; Viikari, JS; Würtz, P | 1 |
Ando, H; Fujimura, A; Ishikawa-Kobayashi, E; Maekawa, T; Nozawa, M; Shiga, T; Takuma, M; Ushijima, K | 1 |
Brozinick, JT; Grove, K; Hawkins, E; Hoang Bui, H; Kievit, P; Kuo, MS; Tan, B | 1 |
RIESER, CH; RIESER, P | 1 |
Cui, TX; Horiuchi, M; Iwai, M; Li, HS; Li, JM; Min, LJ; Okumura, M; Shiuchi, T; Wu, L | 1 |
Karhapää, P; Kuusisto, J; Laakso, M; Moilanen Mykkänen, L; Pihlajamäki, J; Rutanen, J; Vauhkonen, I | 1 |
Bahtyiar, G; Blendea, MC; Ferrario, CM; Jacobs, D; Kumar, P; McFarlane, SI; Ogrin, C; Sha, Q; Sowers, JR; Stas, S; Stump, CS | 1 |
Cucuianu, M; Dican, L | 1 |
Takeuchi, M; Yamagishi, S | 1 |
Derosa, G; Fogari, E; Fogari, R; Lazzari, P; Mugellini, A; Preti, P; Rinaldi, A; Zoppi, A | 1 |
Barroso, I; Cooper, C; Day, IN; Fawcett, KA; Luan, J; O'Rahilly, S; Sandhu, MS; Syddall, H; Wareham, NJ | 1 |
Acikel, C; Caglar, K; Celik, T; Eyileten, T; Oguz, Y; Sonmez, A; Vural, A; Yavuz, I; Yenicesu, M; Yilmaz, MI | 1 |
Chen, K; Clark, SE; Ferrario, CM; Habibi, J; Sowers, JR; Stump, CS; Uptergrove, GM; Wei, Y; Whaley-Connell, AT | 1 |
Acikel, C; Caglar, K; Cakir, E; Eyileten, T; Kurt, Y; Oguz, Y; Saglam, M; Sonmez, A; Tasar, M; Vural, A; Yenicesu, M; Yilmaz, MI | 1 |
Ichikawa, Y | 1 |
Boehm, TM; Bongiovanni, R; Glass, AR; Smith, CE | 1 |
Chow, L; De Gasparo, M; Levens, N | 1 |
Accili, D; Baron, V; Dolais-Kitabgi, J; Gautier, N; Kaliman, P; Lebrun, C; Taylor, S; Van Obberghen, E | 1 |
Hashimoto, N; Hatanaka, Y; Kanashiro, O; Makino, H; Notoya, Y; Nozaki, O; Shimada, F; Suzuki, Y; Taira, M; Yoshida, S | 1 |
Clausen, JO; Echwald, SM; Hansen, L; Hansen, T; Pedersen, O; Rasmussen, SK; Urhammer, SA | 1 |
Alfieri, R; Colao, A; Faggiano, A; Filippella, M; Lombardi, G; Melis, D; Pivonello, R; Salvatore, F; Spagnuolo, G | 1 |
Dunseath, G; Luzio, SD; Owens, DR | 1 |
Akanuma, Y; Izumi, T; Koshio, O; Matsuura, N; Mikami, Y; Odawara, M; Shiba, T; Shibasaki, Y; Tobe, K; Yamamoto, R | 1 |
Accili, D; Elbein, SC; Frapier, C; Lander, E; McKeon, C; Mosthaf, L; Permutt, MA; Ramos, E; Taylor, SI; Ullrich, A | 1 |
Herbertz, L; Langer, K; Schauder, P; Zavelberg, D | 1 |
Cahill, GF; Felig, P; Marliss, E | 1 |
4 review(s) available for valine and Insulin Sensitivity
Article | Year |
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Branched-chain amino acids as a novel biomarker of metabolic disturbances in women with polycystic ovary syndrome - literature review.
Topics: Amino Acids, Branched-Chain; Animals; Biomarkers; Diabetes Mellitus, Type 2; Female; Humans; Insulin Resistance; Isoleucine; Leucine; Obesity; Polycystic Ovary Syndrome; Prediabetic State; Valine | 2022 |
Causal effect of lower birthweight on non-alcoholic fatty liver disease and mediating roles of insulin resistance and metabolites.
Topics: Adult; Alanine; Birth Weight; Child; Genome-Wide Association Study; Humans; Insulin Resistance; Isoleucine; Leucine; Non-alcoholic Fatty Liver Disease; Pediatric Obesity; Polymorphism, Single Nucleotide; Valine | 2023 |
Branched Chain Amino Acids: Beyond Nutrition Metabolism.
Topics: Amino Acids, Branched-Chain; Animals; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Isoleucine; Leucine; Metabolic Diseases; Signal Transduction; Valine | 2018 |
Coagulation factor XIII and atherothrombosis. A mini-review.
Topics: Arteriosclerosis; Diabetes Mellitus, Type 2; Factor XIII; Fibrinolysis; Humans; Insulin Resistance; Leucine; Metabolic Syndrome; Polymorphism, Genetic; Valine | 2003 |
17 trial(s) available for valine and Insulin Sensitivity
Article | Year |
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Brown adipose tissues mediate the metabolism of branched chain amino acids during the transitioning from hyperthyroidism to euthyroidism (TRIBUTE).
Topics: Adipose Tissue, Brown; Amino Acids, Branched-Chain; Fluorodeoxyglucose F18; Humans; Hyperthyroidism; Insulin; Insulin Resistance; Isoleucine; Leucine; Valine | 2022 |
Viral clearance ameliorates hematological and inflammatory markers among diabetic patients infected with hepatitis C genotype 4.
Topics: Adult; Antiviral Agents; Biomarkers; Carbamates; Diabetes Mellitus, Type 2; Female; Genotype; Glycated Hemoglobin; Hepacivirus; Hepatitis C; Humans; Imidazoles; Inflammation; Insulin Resistance; Interleukin-1beta; Male; Middle Aged; Pyrrolidines; Sofosbuvir; Sustained Virologic Response; Treatment Outcome; Valine | 2020 |
Effect of metformin on plasma metabolite profile in the Copenhagen Insulin and Metformin Therapy (CIMT) trial.
Topics: Aged; Carnitine; Chromatography, Liquid; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin Resistance; Isoleucine; Leucine; Lysophospholipids; Male; Mass Spectrometry; Metabolome; Metabolomics; Metformin; Middle Aged; Mitochondria; Tyrosine; Valine | 2018 |
Diets rich in whole grains increase betainized compounds associated with glucose metabolism.
Topics: Adult; Aged; Animals; Betaine; Blood Glucose; Chromatography, Liquid; Cohort Studies; Diet; Dietary Fiber; Feeding Behavior; Female; Finland; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Italy; Male; Metabolic Syndrome; Mice, Inbred C57BL; Middle Aged; Pipecolic Acids; Postprandial Period; Secale; Tandem Mass Spectrometry; Triticum; Valine; Whole Grains | 2018 |
Combination pravastatin and valsartan treatment has additive beneficial effects to simultaneously improve both metabolic and cardiovascular phenotypes beyond that of monotherapy with either drug in patients with primary hypercholesterolemia.
Topics: Angiotensin II Type 1 Receptor Blockers; Body Mass Index; Brachial Artery; C-Reactive Protein; Coronary Artery Disease; Cross-Over Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Drug Therapy, Combination; Endothelium, Vascular; Female; Glycated Hemoglobin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Insulin Resistance; Lipids; Male; Middle Aged; Phenotype; Pravastatin; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2013 |
Short-term administration of an angiotensin II receptor blocker in patients with long-term hemodialysis patients improves insulin resistance.
Topics: Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Glucose; Female; Humans; Insulin Resistance; Kidney Failure, Chronic; Male; Middle Aged; Prospective Studies; Renal Dialysis; Tetrazoles; Valine; Valsartan | 2014 |
Comparison of the effects of three angiotensin II receptor type 1 blockers on metabolic parameters in hypertensive patients with type 2 diabetes mellitus.
Topics: Adiponectin; Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Glucose; Blood Pressure; C-Reactive Protein; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Glycated Hemoglobin; Humans; Hypertension; Insulin Resistance; Lipids; Male; Middle Aged; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2010 |
Valsartan improves {beta}-cell function and insulin sensitivity in subjects with impaired glucose metabolism: a randomized controlled trial.
Topics: Angiotensin Receptor Antagonists; Blood Glucose; Double-Blind Method; Female; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin Resistance; Insulin-Secreting Cells; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2011 |
Influence of telmisartan on insulin response after glucose loading in obese patients with hypertension: ARB trial of hypertension in obese patients with hyperinsulinemia assessed by oral glucose tolerance test (ATHLETE).
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Glucose; Blood Pressure; Female; Glucose; Glucose Tolerance Test; Humans; Hyperinsulinism; Hypertension; Insulin Resistance; Male; Obesity; Telmisartan; Tetrazoles; Valine; Valsartan | 2011 |
Valsartan-induced improvement in insulin sensitivity is not paralleled by changes in microvascular function in individuals with impaired glucose metabolism.
Topics: Adipokines; Angiotensin II Type 1 Receptor Blockers; Blood Glucose; Capillaries; Cytokines; Diabetes Mellitus, Type 2; Female; Humans; Inflammation Mediators; Insulin Resistance; Male; Microvessels; Middle Aged; Tetrazoles; Valine; Valsartan | 2011 |
The effects of telmisartan treatment on the abdominal fat depot in patients with metabolic syndrome and essential hypertension: Abdominal fat Depot Intervention Program of Okayama (ADIPO).
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Blood Glucose; Blood Pressure; Body Mass Index; Body Weight; Female; Humans; Hypertension; Insulin Resistance; Intra-Abdominal Fat; Male; Metabolic Syndrome; Middle Aged; PPAR gamma; Subcutaneous Fat; Telmisartan; Tetrazoles; Tomography, X-Ray Computed; Treatment Outcome; Valine; Valsartan; Waist Circumference | 2013 |
Relationship between the receptor occupancy profile and pleiotropic effects of angiotensin II receptor blockers.
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Area Under Curve; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cross-Over Studies; Dinoprost; Double-Blind Method; Enzyme-Linked Immunosorbent Assay; Humans; Hypertension; Insulin; Insulin Resistance; Irbesartan; Luminescent Measurements; Male; Middle Aged; Oxidative Stress; Radioligand Assay; Receptors, Angiotensin; Tetrazoles; Time Factors; Valine; Valsartan; Young Adult | 2013 |
Comparison of the effects of valsartan and felodipine on plasma leptin and insulin sensitivity in hypertensive obese patients.
Topics: Aged; Antihypertensive Agents; Felodipine; Female; Humans; Hypertension; Insulin Resistance; Leptin; Male; Middle Aged; Obesity; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2005 |
Effect of antihypertensive agents on plasma adiponectin levels in hypertensive patients with metabolic syndrome.
Topics: Adiponectin; Adrenergic beta-Antagonists; Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Body Mass Index; Calcium Channel Blockers; Doxazosin; Female; Humans; Hypertension; Insulin Resistance; Lipids; Male; Metabolic Syndrome; Metoprolol; Middle Aged; Predictive Value of Tests; Prospective Studies; Ramipril; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2007 |
Improving proteinuria, endothelial functions and asymmetric dimethylarginine levels in chronic kidney disease: ramipril versus valsartan.
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Arginine; Biomarkers; Blood Glucose; C-Reactive Protein; Female; Glomerular Filtration Rate; Hemorheology; Humans; Insulin Resistance; Kidney Failure, Chronic; Lipids; Male; Middle Aged; Proteinuria; Ramipril; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan; Vasodilation | 2007 |
Comparative effects of telmisartan and valsartan on insulin resistance in hypertensive patients with metabolic syndrome.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Female; Humans; Hypertension; Insulin Resistance; Male; Metabolic Syndrome; Middle Aged; Telmisartan; Tetrazoles; Valine; Valsartan | 2007 |
Acute effects of valsartan on insulin sensitivity in obese, non-hypertensive subjects with and without type 2 diabetes.
Topics: Adolescent; Adult; Antihypertensive Agents; Cross-Over Studies; Diabetes Mellitus; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Obesity; Tetrazoles; Valine; Valsartan | 2002 |
51 other study(ies) available for valine and Insulin Sensitivity
Article | Year |
---|---|
Detrimental effects of branched-chain amino acids in glucose tolerance can be attributed to valine induced glucotoxicity in skeletal muscle.
Topics: Amino Acids, Branched-Chain; Animals; Glucose; Insulin Resistance; Leucine; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Obesity; Valine | 2022 |
Associations of serum amino acids with insulin resistance among people with and without overweight or obesity: A prospective study in Japan.
Topics: Alanine; Animals; Humans; Insulin; Insulin Resistance; Isoleucine; Japan; Methionine; Obesity; Overweight; Prospective Studies; Thinness; Tyrosine; Valine | 2022 |
Impaired Adipocyte SLC7A10 Promotes Lipid Storage in Association With Insulin Resistance and Altered BCAA Metabolism.
Topics: Adipocytes; Amino Acids; Amino Acids, Branched-Chain; Animals; Fatty Acids; Glucose; Humans; Insulin Resistance; Lipid Metabolism; Mice; Obesity; RNA, Messenger; Tandem Mass Spectrometry; Valine | 2023 |
Metabolomics profiles associated with HbA1c levels in patients with type 2 diabetes.
Topics: Aged; Amino Acids; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Female; Glucose; Glycated Hemoglobin; Glycine; Hexoses; Humans; Insulin Resistance; Male; Metabolomics; Middle Aged; Phosphatidylcholines; Valine | 2019 |
Effect of valine on myotube insulin sensitivity and metabolism with and without insulin resistance.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Amino Acids, Branched-Chain; Animals; Cell Line; Cell Survival; Glycolysis; Insulin; Insulin Resistance; Mice; Mitochondria; Muscle Fibers, Skeletal; Muscle, Skeletal; Signal Transduction; Valine | 2020 |
The impact of direct-acting antiviral treatment on lipid metabolism and insulin resistance in chronic hepatitis C patients: temporary? permanent?
Topics: Aged; Anilides; Antiviral Agents; Benzimidazoles; Blood Glucose; Cholesterol; Cyclopropanes; Drug Therapy, Combination; Female; Fluorenes; Hepacivirus; Hepatitis C, Chronic; Humans; Insulin Resistance; Lactams, Macrocyclic; Lipid Metabolism; Lipoproteins, LDL; Male; Middle Aged; Proline; Ribavirin; Ritonavir; Sofosbuvir; Sulfonamides; Sustained Virologic Response; Treatment Outcome; Triglycerides; Valine | 2020 |
Differences in gene expression of enzymes involved in branched-chain amino acid metabolism of abdominal subcutaneous adipose tissue between pregnant women with and without PCOS.
Topics: Adult; Amino Acids, Branched-Chain; Body Mass Index; Female; Gene Expression; Humans; Insulin Resistance; Isoleucine; Leucine; Polycystic Ovary Syndrome; Pregnancy; Pregnancy Complications; Prognosis; Real-Time Polymerase Chain Reaction; RNA, Messenger; Subcutaneous Fat, Abdominal; Valine | 2021 |
The outcomes of glucose abnormalities in chronic hepatitis C patients receiving interferon-free direct antiviral agents.
Topics: 2-Naphthylamine; Aged; Anilides; Antiviral Agents; Carbamates; Cyclopropanes; Drug Therapy, Combination; Female; Genotype; Glucose; Hepacivirus; Hepatitis C, Chronic; Humans; Imidazoles; Insulin Resistance; Insulin-Secreting Cells; Isoquinolines; Lactams, Macrocyclic; Macrocyclic Compounds; Male; Middle Aged; Proline; Prospective Studies; Pyrrolidines; Ritonavir; Sofosbuvir; Sulfonamides; Uracil; Valine | 2017 |
Inhibition of the CD36 receptor reduces visceral fat accumulation and improves insulin resistance in obese mice carrying the BDNF-
Topics: Animals; Benzofurans; Brain-Derived Neurotrophic Factor; CD36 Antigens; Cell Differentiation; Diet, High-Fat; Insulin Resistance; Intra-Abdominal Fat; Male; Methionine; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Obese; Mutation; Obesity; Valine | 2018 |
Nine Amino Acids Are Associated With Decreased Insulin Secretion and Elevated Glucose Levels in a 7.4-Year Follow-up Study of 5,181 Finnish Men.
Topics: Aged; Alanine; Amino Acids; Aspartic Acid; Blood Glucose; Diabetes Mellitus, Type 2; Finland; Follow-Up Studies; Glutamic Acid; Humans; Insulin Resistance; Insulin Secretion; Isoleucine; Leucine; Male; Metabolomics; Middle Aged; Phenylalanine; Risk Factors; Tryptophan; Tyrosine; Valine | 2019 |
Arginase inhibition alleviates hypertension in the metabolic syndrome.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Arginase; Blood Pressure; Citrulline; Endothelium, Vascular; Enzyme Inhibitors; Hyperinsulinism; Hypertension; Hypertriglyceridemia; Hypolipidemic Agents; Insulin Resistance; Male; Metabolic Syndrome; Nitric Oxide; Ornithine; Random Allocation; Rats; Rats, Wistar; Reactive Oxygen Species; Valine | 2013 |
Hepatosteatosis and hepatic insulin resistance are blunted by argirein, an anti-inflammatory agent, through normalizing endoplasmic reticulum stress and apoptosis in diabetic liver.
Topics: Animals; Anthraquinones; Anti-Inflammatory Agents; Apoptosis; Arginine; Diabetes Mellitus, Experimental; Diet, High-Fat; Drug Combinations; eIF-2 Kinase; Endoplasmic Reticulum Stress; Glucose; Glucose Transporter Type 4; Glutathione Peroxidase; Glycogen; Heat-Shock Proteins; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Liver; Male; PPAR alpha; PPAR gamma; Rats; Rats, Sprague-Dawley; Receptors, Leptin; Tetrazoles; Transcription Factor CHOP; Valine; Valsartan | 2013 |
Effects of combination therapy with vildagliptin and valsartan in a mouse model of type 2 diabetes.
Topics: Adamantane; Adiponectin; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Glucose; Cytokines; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Drug Therapy, Combination; Fatty Liver; Homeodomain Proteins; Inflammation; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Mice; Mice, Inbred C57BL; Nitriles; Phlorhizin; Pyrrolidines; Tetrazoles; Trans-Activators; Valine; Valsartan; Vildagliptin | 2013 |
Effects of individual branched-chain amino acids deprivation on insulin sensitivity and glucose metabolism in mice.
Topics: Amino Acids, Branched-Chain; AMP-Activated Protein Kinases; Animals; Blood Glucose; Blotting, Western; Cell Line; Gluconeogenesis; Glucose-6-Phosphatase; Hep G2 Cells; Hepatocytes; Humans; Insulin Resistance; Isoleucine; Male; Mice; Mice, Inbred C57BL; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Protein S6 Kinases, 70-kDa; Ribosomal Protein S6 Kinases, 90-kDa; Signal Transduction; TOR Serine-Threonine Kinases; Valine | 2014 |
Plasma levels of lysine, tyrosine, and valine during pregnancy are independent risk factors of insulin resistance and gestational diabetes.
Topics: Adult; Aging; Asian People; Blood Glucose; Blood Pressure; Diabetes, Gestational; Diet; Energy Intake; Female; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Lysine; Pregnancy; Risk Factors; Tyrosine; Valine | 2015 |
Suppression of Endogenous Glucose Production by Isoleucine and Valine and Impact of Diet Composition.
Topics: Animals; Blood Glucose; Diet; Diet, High-Fat; Dietary Fats; Dietary Proteins; Gluconeogenesis; Hypothalamus; Insulin Resistance; Isoleucine; Liver; Male; Rats, Sprague-Dawley; Valine | 2016 |
Tryptophan Predicts the Risk for Future Type 2 Diabetes.
Topics: Adult; Aged; Biomarkers; Blood Glucose; Case-Control Studies; China; Diabetes Mellitus, Type 2; Fasting; Female; Humans; Insulin; Insulin Resistance; Isoleucine; Leucine; Longitudinal Studies; Male; Middle Aged; Phenylalanine; Predictive Value of Tests; Prognosis; Risk Factors; Tryptophan; Tyrosine; Valine | 2016 |
High concentration of branched-chain amino acids promotes oxidative stress, inflammation and migration of human peripheral blood mononuclear cells via mTORC1 activation.
Topics: Amino Acids, Branched-Chain; Cell Movement; Humans; Inflammation; Insulin Resistance; Interleukin-6; Isoleucine; Leucine; Leukocytes, Mononuclear; Mechanistic Target of Rapamycin Complex 1; Mitochondria; NF-kappa B; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; TOR Serine-Threonine Kinases; Tumor Necrosis Factor-alpha; Valine | 2017 |
Manganese superoxide dismutase Ala16Val polymorphism is associated with the development of type 2 diabetes in Japanese-Americans.
Topics: Alanine; Amino Acid Substitution; Diabetes Mellitus, Type 2; Female; Glucose Intolerance; Glucose Tolerance Test; Humans; Insulin; Insulin Resistance; Japan; Male; Middle Aged; Polymorphism, Genetic; Reactive Oxygen Species; Superoxide Dismutase; United States; Valine | 2008 |
The A98V single nucleotide polymorphism (SNP) in hepatic nuclear factor 1 alpha (HNF-1alpha) is associated with insulin sensitivity and beta-cell function.
Topics: Adult; Alanine; Diabetes Mellitus, Type 2; Female; Genetic Linkage; Genotype; Hepatocyte Nuclear Factor 1-alpha; Humans; Insulin; Insulin Resistance; Insulin-Secreting Cells; Male; Middle Aged; Polymorphism, Single Nucleotide; Valine | 2008 |
[The effects of renin-angiotensin system blockade on the liver steatosis in rats on long-term high-fat diet].
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Dietary Fats; Fatty Liver; Immunohistochemistry; Insulin Resistance; Ion Channels; Liver; Male; Mitochondrial Proteins; Perindopril; Rats; Rats, Wistar; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazoles; Time Factors; Transforming Growth Factor beta1; Uncoupling Protein 2; Valine; Valsartan | 2008 |
Val1483Ile in FASN gene is linked to central obesity and insulin sensitivity in adult white men.
Topics: Adipose Tissue; Adiposity; Adult; Age Factors; Blood Glucose; Blood Pressure; Body Mass Index; Case-Control Studies; Down-Regulation; Fatty Acid Synthase, Type I; Female; Gene Frequency; Genetic Predisposition to Disease; Humans; Insulin Resistance; Isoleucine; Male; Middle Aged; Obesity; Phenotype; Polymorphism, Single Nucleotide; Risk Factors; Sex Factors; Time Factors; Valine; Waist-Hip Ratio; Weight Gain | 2009 |
Effect of Renin-Angiotensin system blockade on insulin resistance and inflammatory parameters in patients with impaired glucose tolerance.
Topics: Adiponectin; Adult; Angiotensin II Type 1 Receptor Blockers; C-Reactive Protein; Glucose Intolerance; Humans; Insulin Resistance; Male; Middle Aged; Prospective Studies; Renin-Angiotensin System; Retinol-Binding Proteins, Plasma; Tetrazoles; Valine; Valsartan | 2010 |
Valsartan protects pancreatic islets and adipose tissue from the inflammatory and metabolic consequences of a high-fat diet in mice.
Topics: Adipocytes; Adipose Tissue; Angiotensin II Type 1 Receptor Blockers; Animal Feed; Animals; Body Weight; Cytokines; Diabetes Mellitus, Type 2; Dietary Fats; Disease Models, Animal; Gene Expression; Glucose Intolerance; Inflammation; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Macrophages; Male; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Mitochondria; Tetrazoles; Valine; Valsartan | 2010 |
Angiotensin II type 1 receptor blockers improve insulin sensitivity in patients with schizophrenia being treated with olanzapine.
Topics: Angiotensin II Type 1 Receptor Blockers; Antipsychotic Agents; Benzimidazoles; Benzoates; Benzodiazepines; Female; Humans; Hyperinsulinism; Insulin Resistance; Male; Middle Aged; Olanzapine; Receptor, Angiotensin, Type 1; Schizophrenia; Telmisartan; Tetrazoles; Valine; Valsartan | 2011 |
Irbesartan prevents metabolic syndrome in rats via activation of peroxisome proliferator-activated receptor γ.
Topics: Adiponectin; Adipose Tissue; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Gene Expression Regulation; Glucose Transporter Type 4; Hypertension; Hypertriglyceridemia; Hypoglycemic Agents; Insulin Resistance; Irbesartan; Male; Metabolic Syndrome; Pioglitazone; PPAR gamma; Rats; Rats, Inbred SHR; RNA, Messenger; Tetrazoles; Thiazolidinediones; Valine; Valsartan | 2011 |
Resistance to antihypertensive treatment: reality or artifact of reasoning?
Topics: Angiotensin II Type 1 Receptor Blockers; Female; Humans; Insulin Resistance; Male; Microvessels; Tetrazoles; Valine; Valsartan | 2011 |
To PRESERVE and protect: targeting the microcirculation in prevention of diabetes and its complications.
Topics: Angiotensin II Type 1 Receptor Blockers; Female; Humans; Insulin Resistance; Male; Microvessels; Tetrazoles; Valine; Valsartan | 2011 |
Valsartan, independently of AT1 receptor or PPARγ, suppresses LPS-induced macrophage activation and improves insulin resistance in cocultured adipocytes.
Topics: 3T3-L1 Cells; Adipocytes, White; Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cells, Cultured; Coculture Techniques; Humans; Insulin Resistance; Macrophage Activation; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; PPAR gamma; Receptor, Angiotensin, Type 1; RNA Interference; RNA, Small Interfering; Tetrazoles; Valine; Valsartan | 2012 |
Effects of valsartan on diabetic cardiomyopathy in rats with type 2 diabetes mellitus.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Collagen Type I; Collagen Type III; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Hydroxyproline; Insulin Resistance; Male; Myocardium; Rats; Rats, Wistar; Tetrazoles; Valine; Valsartan | 2010 |
Circulating branched-chain amino acid concentrations are associated with obesity and future insulin resistance in children and adolescents.
Topics: Adolescent; Amino Acids, Branched-Chain; Biomarkers; Blood Glucose; Body Mass Index; Child; Child Nutrition Disorders; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Fasting; Female; Humans; Insulin; Insulin Resistance; Insulin Secretion; Isoleucine; Leucine; Longitudinal Studies; Male; Massachusetts; Obesity; Predictive Value of Tests; Valine | 2013 |
Branched-chain and aromatic amino acids are predictors of insulin resistance in young adults.
Topics: Adult; Amino Acids; Female; Humans; Insulin Resistance; Isoleucine; Leucine; Male; Phenylalanine; Tyrosine; Valine; Young Adult | 2013 |
Effects of telmisartan and valsartan on insulin sensitivity in obese diabetic mice.
Topics: Adiponectin; Adipose Tissue; Animals; Benzimidazoles; Benzoates; Body Weight; Diabetes Mellitus; Eating; Fatty Acid Synthases; Fatty Acid-Binding Proteins; Gene Expression Regulation; Homeostasis; Insulin Resistance; Interleukin-6; Male; Mice; Mice, Obese; PPAR gamma; RNA, Messenger; Telmisartan; Tetrazoles; Tumor Necrosis Factor-alpha; Valine; Valsartan | 2013 |
Plasma sphingolipids are biomarkers of metabolic syndrome in non-human primates maintained on a Western-style diet.
Topics: Animals; Biomarkers; Ceramides; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Disease Progression; Fructose; Insulin Resistance; Macaca mulatta; Male; Metabolic Syndrome; Obesity; Risk Factors; Serine C-Palmitoyltransferase; Sphingolipids; Valine | 2013 |
REVERSAL OF INSULIN RESISTANCE IN RED CELL SUGAR TRANSPORT.
Topics: Arabinose; Biological Transport; Carbohydrate Metabolism; Chymotrypsin; Erythrocytes; Fructose; Galactose; Glycerol; Insulin; Insulin Resistance; Lipase; Mannose; Permeability; Pharmacology; Phospholipases; Research; Ribose; Sorbose; Threonine; Urea; Valine; Xylose | 1964 |
Angiotensin II type-1 receptor blocker valsartan enhances insulin sensitivity in skeletal muscles of diabetic mice.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Blood Glucose; Crosses, Genetic; Deoxyglucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Energy Intake; Gene Expression Regulation; Glucose Transporter Type 4; Imidazoles; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mice, Obese; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Phosphoproteins; Phosphorylation; Protein Processing, Post-Translational; Protein Transport; Pyridines; Signal Transduction; Superoxides; Tetrazoles; Tumor Necrosis Factor-alpha; Valine; Valsartan | 2004 |
The Val103Ile polymorphism of melanocortin-4 receptor regulates energy expenditure and weight gain.
Topics: Adult; Aged; Alleles; Blood Glucose; Calorimetry, Indirect; Energy Metabolism; Fatty Acids, Nonesterified; Finland; Gene Frequency; Glucose Clamp Technique; Humans; Insulin; Insulin Resistance; Isoleucine; Middle Aged; Oxidation-Reduction; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Prospective Studies; Receptor, Melanocortin, Type 4; Sequence Analysis, DNA; Valine; Weight Gain | 2004 |
Abrogation of oxidative stress improves insulin sensitivity in the Ren-2 rat model of tissue angiotensin II overexpression.
Topics: Administration, Oral; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cyclic N-Oxides; Disease Models, Animal; Glucose; Hypertension; Insulin; Insulin Resistance; Male; Muscle, Skeletal; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Spin Labels; Tetrazoles; Valine; Valsartan | 2005 |
Telmisartan is a promising cardiometabolic sartan due to its unique PPAR-gamma-inducing property.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Cardiovascular Diseases; Diabetes Mellitus; Diabetes Mellitus, Type 2; Humans; Hypertension; Insulin Resistance; PPAR gamma; Renin-Angiotensin System; Telmisartan; Tetrazoles; Valine; Valsartan | 2005 |
PARL Leu262Val is not associated with fasting insulin levels in UK populations.
Topics: Aged; Amino Acid Substitution; Body Mass Index; Cohort Studies; Fasting; Genotype; Humans; Insulin; Insulin Resistance; Leucine; Male; Metalloproteases; Middle Aged; Mitochondrial Proteins; Models, Genetic; United Kingdom; Valine | 2006 |
NADPH oxidase contributes to vascular inflammation, insulin resistance, and remodeling in the transgenic (mRen2) rat.
Topics: Animals; Animals, Genetically Modified; Apoptosis; Blood Pressure; Blotting, Western; C-Reactive Protein; Cells, Cultured; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Insulin Resistance; Male; Muscle, Smooth, Vascular; NADPH Oxidases; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sensitivity and Specificity; Superoxide Dismutase; Tetrazoles; Valine; Valsartan; Vasculitis | 2007 |
Normal valine disposal in obese subjects with impaired glucose disposal: evidence for selective insulin resistance.
Topics: Blood Glucose; Female; Glucose; Humans; Insulin; Insulin Resistance; Male; Metabolic Clearance Rate; Obesity; Valine | 1981 |
Improved glucose metabolism following blockade of angiotensin converting enzyme but not angiotensin AT1 receptors.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzazepines; Blood Glucose; Blood Pressure; Body Weight; Drug Tolerance; Glucose Intolerance; Hypertension; Insulin Resistance; Lipids; Rats; Rats, Inbred SHR; Tetrazoles; Valine; Valsartan | 1995 |
Antibodies to the extracellular receptor domain restore the hormone-insensitive kinase and conformation of the mutant insulin receptor valine 382.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Humans; Insulin; Insulin Resistance; Kinetics; Mice; Mutagenesis, Site-Directed; Peptides; Phosphorylation; Protein Conformation; Protein-Tyrosine Kinases; Receptor, Insulin; Recombinant Proteins; Transfection; Valine | 1993 |
A glycine-1008 to valine mutation in the insulin receptor in a woman with type A insulin resistance.
Topics: Adult; Female; Glucose Tolerance Test; Glycine; Humans; Insulin; Insulin Resistance; Japan; Mutation; Pedigree; Polymerase Chain Reaction; Protein-Tyrosine Kinases; Receptor, Insulin; Valine | 1993 |
The Val985Met insulin-receptor variant in the Danish Caucasian population: lack of associations with non-insulin-dependent diabetes mellitus or insulin resistance.
Topics: Blood Glucose; C-Peptide; Denmark; Diabetes Mellitus, Type 2; Genetic Variation; Genotype; Heterozygote; Homozygote; Humans; Insulin; Insulin Resistance; Methionine; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Receptor, Insulin; Reference Values; Valine; White People | 1997 |
Evaluation of circulating levels and renal clearance of natural amino acids in patients with Cushing's disease.
Topics: Adult; Alanine; Amino Acids; Blood Glucose; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Creatinine; Cushing Syndrome; Cystine; Cystinuria; Fasting; Female; Glucose Tolerance Test; Humans; Hydrocortisone; Insulin; Insulin Resistance; Isoleucine; Kidney; Leucine; Male; Middle Aged; Valine | 2002 |
Defect in tyrosine kinase activity of the insulin receptor from a patient with insulin resistance and acanthosis nigricans.
Topics: Acanthosis Nigricans; Adenosine Triphosphate; Adolescent; Alleles; B-Lymphocytes; Binding Sites; Cell Transformation, Viral; Cloning, Molecular; DNA; Glycine; Humans; Insulin; Insulin Resistance; Male; Mutation; Peptide Mapping; Phosphorylation; Protein-Tyrosine Kinases; Receptor, Insulin; Valine | 1990 |
A mutation in the insulin receptor gene that impairs transport of the receptor to the plasma membrane and causes insulin-resistant diabetes.
Topics: Cells, Cultured; Cloning, Molecular; Diabetes Mellitus; Female; Genetic Linkage; Homozygote; Humans; Insulin Resistance; Mutation; Pedigree; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Protein Processing, Post-Translational; Receptor, Insulin; Transfection; Valine | 1989 |
Sex-specific differences in plasma branched-chain keto acid levels in obesity.
Topics: Blood Glucose; Body Composition; Female; Hemiterpenes; Humans; Insulin; Insulin Resistance; Isoleucine; Keto Acids; Leucine; Male; Middle Aged; Obesity; Sex Characteristics; Valine | 1987 |
Plasma amino acid levels and insulin secretion in obesity.
Topics: Adolescent; Adult; Amino Acids; Blood Glucose; Fasting; Feedback; Female; Glucose; Glycine; Humans; Insulin; Insulin Resistance; Insulin Secretion; Isoleucine; Leucine; Male; Middle Aged; Obesity; Pancreas; Phenylalanine; Tyrosine; Valine | 1969 |