valine has been researched along with Inflammation in 53 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (5.66) | 18.7374 |
| 1990's | 2 (3.77) | 18.2507 |
| 2000's | 22 (41.51) | 29.6817 |
| 2010's | 22 (41.51) | 24.3611 |
| 2020's | 4 (7.55) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, X; Kuang, Y; Li, J; Liu, N; Liu, P; Peng, C; Yan, B; Yi, X; Zhu, W | 1 |
| Caspers, MPM; Gart, E; Keijer, J; Kleemann, R; Menke, A; Morrison, MC; Salic, K; Snabel, J; van Duyvenvoorde, W; van Trigt, N | 1 |
| Bi, C; Cheng, B; Ma, Q; Shen, J; Zhang, J; Zhou, X | 1 |
| Abdel Moneim, A; Mabrouk, D; Mahmoud, B; Suleiman, HA; Zaky, MY | 1 |
| Barbier, O; Bigo, C; Da Silva, MS; Rudkowska, I | 1 |
| Burchill, MA; Crochet, N; Dran, RJ; Edwards, MG; Gale, M; Kriss, MS; Roby, JA; Rosen, HR; Stone, AE; Wind-Rotolo, M | 1 |
| Araki, E; Goto, R; Igata, M; Kawasaki, S; Kawashima, J; Kitano, S; Kondo, T; Matsumura, T; Matsuyama, R; Miyagawa, K; Motoshima, H; Ono, K | 1 |
| Cheung, AK; Huang, Y; Liu, X; Zhou, G | 1 |
| Chen, H; Hu, X; Jiang, Z; Li, J; Liu, X; Steinhoff, G; Wang, L; Xu, Y; Yu, H; Zhang, Z | 1 |
| Gonçalves, NP; Saraiva, MJ; Teixeira-Coelho, M | 1 |
| Howard, A; Kopp, JB; Levi, M; Li, C; Qiu, L; Solis, N; Wang, W; Wang, X | 1 |
| Li, X; Li, Y; Lu, J; Peng, Y; Shen, Q; Wang, Y; Yin, D | 1 |
| Farmer, L; Hogan, JK; Hoock, TC; Mahajan, S; Oh, L; Salituro, FG; Shlyakhter, D | 1 |
| Nakajima, T; Nenoi, M; Vares, G; Wang, B | 1 |
| Civantos, E; Egido, J; Mas, S; Peiró, C; Ruiz-Ortega, M; Sánchez, MS; Vázquez, C; Zhenyukh, O | 1 |
| Dong, YF; Fukuda, M; Kataoka, K; Kim-Mitsuyama, S; Matsuba, S; Nakamura, T; Ogawa, H; Tamamaki, N; Tokutomi, Y; Yamamoto, E | 1 |
| Baker, AB; Beigel, R; Chatzizisis, YS; Coskun, AU; Daley, W; Edelman, ER; Feldman, CL; Gerrity, RG; Jonas, M; Maynard, C; Stone, BV; Stone, PH | 1 |
| Aoyama, I; Bomsztyk, K; Komers, R; Koopmeiners, JS; Naito, M; Schnaper, HW; Shenoy, A | 1 |
| Carter, JD; Cole, BK; Keller, SR; Nadler, JL; Nunemaker, CS; Wu, R | 1 |
| Cunningham, ET; Roe, RH | 1 |
| Finckenberg, P; Kaheinen, P; Levijoki, J; Louhelainen, M; Merasto, S; Mervaala, E; Vahtola, E | 1 |
| Kamal, F; Morioka, T; Oite, T; Piao, H; Yanakieva-Georgieva, N | 1 |
| Janahmadi, M; Javan, M; Khakpay, R; Semnanian, S | 1 |
| Antoniades, C; Kardara, D; Koumallos, N; Kyvelou, SM; Papageorgiou, N; Stefanadis, C; Tousoulis, D; Vasiliadou, C; Vlachopoulos, C; Xaplanteris, P | 1 |
| Brown, NJ; Gamboa, JL; Ikizler, TA; Luther, JM; Pretorius, M; Todd-Tzanetos, DR; Yu, C | 1 |
| Kalantar-Zadeh, K; Zaritsky, JJ | 1 |
| Cao, F; Li, W; Liu, B; Shen, M; Sun, D; Wang, S; Zhang, Z | 1 |
| Battiston, FG; da Cruz, IB; da Rocha, MI; Duarte, MM; Krewer, Cda C; Lera, JP; Mânica-Cattani, MF; Maris, AF; Montano, MA; Rosa, G; Soares, FA; Trott, A | 1 |
| Alili, R; Blaak, EE; Clément, K; Cleutjens, JP; Diamant, M; Essers, Y; Goossens, GH; Jocken, JW; Moors, CC; van der Zijl, NJ; Venteclef, N | 1 |
| Hama, A; Sagen, J; Woon Lee, J | 1 |
| Heinke, B; Müller, F; Sandkühler, J | 1 |
| Krause, S; Lochmüller, H; Müller-Felber, W; Müller-Höcker, J; Najmabadi, H; Pongratz, D; Schlotter-Weigel, B; Walter, MC; Wiendl, H | 1 |
| Li, Q; Liu, L; Xiao, J; Xu, Z; Zhao, S | 1 |
| Albertini, A; Bachetti, T; Bastianon, D; Cadei, M; Comini, L; Curello, S; Ferrari, R; Finazzi, D; Francolini, G; Grigolato, P; Suzuki, H; Valetti, B | 1 |
| Cairns, BE; Hu, JW; Lam, DK; Sessle, BJ | 1 |
| Brownlow, N; Dibb, NJ; Domin, J; Taylor, JR | 1 |
| Kolb-Bachofen, V; Lerzynski, G; Suschek, CV | 1 |
| Higaki, J; Horiuchi, M; Iwai, M; Mogi, M; Oshita, A; Suzuki, J; Yoshii, T | 1 |
| Danielson, E; Glynn, RJ; Ridker, PM; Rifai, N | 1 |
| Egashira, K; Funakoshi, K; Ihara, Y; Nakano, K; Ohtani, K; Sata, M; Sunagawa, K; Zhao, G | 1 |
| de Gasparo, M | 1 |
| Ayala, JM; Azimzadeh, AM; DeMartino, JA; Iliff, S; Kawka, DW; Lu, M; Lyons, K; Miller, GG; Mills, SG; Mudgett, JS; Nguyen, BN; Peterson, LB; Pierson, RN; Schröder, C; Siciliano, SJ; Singer, II; Springer, MS; Wu, G; Zhang, T | 1 |
| Dagenais, NJ; Dryden, WF; Hanafy, S; Jamali, F | 1 |
| Anand, IS; Barlera, S; Carretta, E; Cohn, JN; Latini, R; Maggioni, AP; Masson, S; Staszewsky, L; Tognoni, G; Wong, M | 1 |
| Bless, NM; Charlton, J; Czermak, BJ; Friedl, HP; Schmal, H; Smith, D; Ward, PA | 1 |
| Breu, V; Dechend, R; Fiebeler, A; Ganten, D; Gulba, D; Haller, H; Luft, FC; Luther, T; Mackman, N; Mervaala, EM; Müller, DN; Park, JK; Schmidt, F; Schneider, W; Theuer, J | 1 |
| Bhave, G; Carlton, SM; Gereau , RW; Karim, F | 1 |
| Hu, JY; Zhao, ZQ | 1 |
| Akishita, M; Chen, R; de Gasparo, M; Horiuchi, M; Iwai, M; Li, Z; Nakagami, H; Suzuki, J; Wu, L | 1 |
| Dubner, R; Hylden, JL; Ren, K; Ruda, MA; Williams, GM | 1 |
| Ando, Y; Araki, S; Ikegawa, S; Inoue, M; Miyazaki, A; Morino, Y | 1 |
| Björnesjö, KB | 1 |
| Potel, M; Wagner, J | 1 |
1 review(s) available for valine and Inflammation
| Article | Year |
|---|---|
New basic science initiatives with the angiotensin II receptor blocker valsartan.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Atherosclerosis; Cell Proliferation; Endothelium, Vascular; Humans; Inflammation; Tetrazoles; Valine; Valsartan; Vasoconstriction; Ventricular Remodeling | 2000 |
6 trial(s) available for valine and Inflammation
| Article | Year |
|---|---|
Viral clearance ameliorates hematological and inflammatory markers among diabetic patients infected with hepatitis C genotype 4.
Topics: Adult; Antiviral Agents; Biomarkers; Carbamates; Diabetes Mellitus, Type 2; Female; Genotype; Glycated Hemoglobin; Hepacivirus; Hepatitis C; Humans; Imidazoles; Inflammation; Insulin Resistance; Interleukin-1beta; Male; Middle Aged; Pyrrolidines; Sofosbuvir; Sustained Virologic Response; Treatment Outcome; Valine | 2020 |
Comparative effects of angiotensin-converting enzyme inhibition and angiotensin-receptor blockade on inflammation during hemodialysis.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Blood Coagulation; CD40 Ligand; Cross-Over Studies; Cytokines; Double-Blind Method; Female; Hemodynamics; Humans; Inflammation; Kidney Failure, Chronic; Male; Middle Aged; Oxidative Stress; Ramipril; Renal Dialysis; Renin; Tetrazoles; Valine; Valsartan | 2012 |
Valsartan improves adipose tissue function in humans with impaired glucose metabolism: a randomized placebo-controlled double-blind trial.
Topics: Adipocytes; Adipose Tissue; Antihypertensive Agents; Biomarkers; Blood Pressure; Capillaries; Cell Hypoxia; Cell Size; Chemotactic Factors; Double-Blind Method; Fasting; Female; Gene Expression Regulation; Glucose; Humans; Inflammation; Insulin; Lipolysis; Macrophages; Male; Middle Aged; Placebos; Postprandial Period; Tetrazoles; Valine; Valsartan | 2012 |
Simvastatin reduces interleukin-1beta secretion by peripheral blood mononuclear cells in patients with essential hypertension.
Topics: Aged; Angiotensin II; Cross-Sectional Studies; Drug Therapy, Combination; Female; Humans; Hypertension; Inflammation; Interleukin-1; Leukocytes, Mononuclear; Lipids; Male; Middle Aged; Simvastatin; Tetrazoles; Valine; Valsartan | 2004 |
Valsartan, blood pressure reduction, and C-reactive protein: primary report of the Val-MARC trial.
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biomarkers; Blood Pressure; C-Reactive Protein; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Inflammation; Male; Middle Aged; Prospective Studies; Tetrazoles; Valine; Valsartan | 2006 |
Clinical, neurohormonal, and inflammatory markers and overall prognostic role of chronic obstructive pulmonary disease in patients with heart failure: data from the Val-HeFT heart failure trial.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Cause of Death; Confidence Intervals; Creatinine; Echocardiography; Female; Follow-Up Studies; Heart Failure; Humans; Inflammation; Male; Middle Aged; Norepinephrine; Pulmonary Disease, Chronic Obstructive; Survival Rate; Tetrazoles; Treatment Outcome; Troponin T; Valine; Valsartan | 2007 |
46 other study(ies) available for valine and Inflammation
| Article | Year |
|---|---|
Topical VX-509 attenuates psoriatic inflammation through the STAT3/FABP5 pathway in keratinocytes.
Topics: Animals; Disease Models, Animal; Fatty Acid-Binding Proteins; Heterocyclic Compounds, 2-Ring; Imiquimod; Inflammation; Keratinocytes; Mice; Mice, Inbred BALB C; Neoplasm Proteins; Psoriasis; Skin; STAT3 Transcription Factor; Valine | 2022 |
Intervention with isoleucine or valine corrects hyperinsulinemia and reduces intrahepatic diacylglycerols, liver steatosis, and inflammation in Ldlr-/-.Leiden mice with manifest obesity-associated NASH.
Topics: Amino Acids, Branched-Chain; Animals; Diglycerides; Hyperinsulinism; Inflammation; Isoleucine; Liver; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Obesity; Valine | 2022 |
Branched-chain amino acid modulation of lipid metabolism, gluconeogenesis, and inflammation in a finishing pig model: targeting leucine and valine.
Topics: Amino Acids, Branched-Chain; Fatty Acids; Gluconeogenesis; Humans; Inflammation; Leucine; Lipid Metabolism; Lipids; Swine; Valine | 2023 |
Whey protein hydrolysate and branched-chain amino acids downregulate inflammation-related genes in vascular endothelial cells.
Topics: Amino Acids, Branched-Chain; Anti-Inflammatory Agents; Caseins; Dairy Products; Down-Regulation; Endothelial Cells; Endothelium, Vascular; Gene Expression; Glutamine; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Isoleucine; Leucine; Nitric Oxide Synthase Type III; Protein Hydrolysates; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Valine; Vascular Cell Adhesion Molecule-1; Whey Proteins | 2017 |
Rapid reversal of innate immune dysregulation in blood of patients and livers of humanized mice with HCV following DAA therapy.
Topics: Aged; Animals; Antiviral Agents; Benzazepines; Carbamates; Disease Models, Animal; Female; Gene Expression Regulation; Hepacivirus; Hepatitis C, Chronic; Hepatocytes; Humans; Imidazoles; Immunity, Innate; Indoles; Inflammation; Isoquinolines; Liver; Male; Mice; Middle Aged; Pyrrolidines; Sulfonamides; Valine | 2017 |
Effects of combination therapy with vildagliptin and valsartan in a mouse model of type 2 diabetes.
Topics: Adamantane; Adiponectin; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Glucose; Cytokines; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Drug Therapy, Combination; Fatty Liver; Homeodomain Proteins; Inflammation; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Mice; Mice, Inbred C57BL; Nitriles; Phlorhizin; Pyrrolidines; Tetrazoles; Trans-Activators; Valine; Valsartan; Vildagliptin | 2013 |
Valsartan slows the progression of diabetic nephropathy in db/db mice via a reduction in podocyte injury, and renal oxidative stress and inflammation.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Progression; Extracellular Matrix Proteins; Fibronectins; Gene Expression Regulation; Inflammation; Intracellular Signaling Peptides and Proteins; Kidney; Kidney Cortex; Kidney Glomerulus; Membrane Proteins; Mice; Oxidative Stress; Plasminogen Activator Inhibitor 1; Podocytes; RNA, Messenger; Tetrazoles; Transforming Growth Factor beta1; Treatment Outcome; Valine; Valsartan; WT1 Proteins | 2014 |
Preconditioning via angiotensin type 2 receptor activation improves therapeutic efficacy of bone marrow mononuclear cells for cardiac repair.
Topics: Angiotensin II; Animals; Apoptosis; Bone Marrow Cells; Cell Transplantation; Coculture Techniques; Echocardiography; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Inflammation; Leukocytes, Mononuclear; Male; Myocardial Infarction; Myocytes, Cardiac; Neovascularization, Physiologic; Nitric Oxide; Nitric Oxide Synthase Type III; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Stem Cell Transplantation; Tetrazoles; Valine; Valsartan; Vascular Endothelial Growth Factor A | 2013 |
The inflammatory response to sciatic nerve injury in a familial amyloidotic polyneuropathy mouse model.
Topics: Amyloid Neuropathies, Familial; Animals; Disease Models, Animal; Female; Functional Laterality; Ganglia, Spinal; Gene Expression Regulation; Humans; Inflammation; Locomotion; Male; Methionine; Mice; Mice, Transgenic; Mutation; Pain Measurement; Prealbumin; Schwann Cells; Sciatic Neuropathy; Time Factors; Valine | 2014 |
Protective effects of aliskiren and valsartan in mice with diabetic nephropathy.
Topics: Albumins; Amides; Animals; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Endoplasmic Reticulum Stress; Fumarates; Inflammation; Lipid Metabolism; Male; Membrane Proteins; Mesangial Cells; Mice, Inbred DBA; Podocytes; Protective Agents; Proteinuria; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan | 2014 |
Valsartan blocked alcohol-induced, Toll-like receptor 2 signaling-mediated inflammation in human vascular endothelial cells.
Topics: Angiotensin Receptor Antagonists; Apoptosis; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Ethanol; Humans; In Vitro Techniques; Inflammation; Interleukin-6; NF-kappa B; Receptor, Angiotensin, Type 1; RNA, Small Interfering; Signal Transduction; Tetrazoles; TNF Receptor-Associated Factor 6; Toll-Like Receptor 2; Tumor Necrosis Factor-alpha; Valine; Valsartan | 2014 |
VX-509 (decernotinib) is a potent and selective janus kinase 3 inhibitor that attenuates inflammation in animal models of autoimmune disease.
Topics: Animals; Arthritis, Experimental; Autoimmune Diseases; Disease Models, Animal; Edema; Female; Heterocyclic Compounds, 2-Ring; Humans; Hypersensitivity, Delayed; Inflammation; Janus Kinase 1; Janus Kinase 2; Janus Kinase 3; Male; Mice; Protein Kinase Inhibitors; Rats; Valine | 2015 |
Chronic Intake of Japanese Sake Mediates Radiation-Induced Metabolic Alterations in Mouse Liver.
Topics: Alcohol Drinking; Alcoholic Beverages; Animals; Antioxidants; Dose Fractionation, Radiation; Electrophoresis, Capillary; Ethanol; Female; Glutathione; Inflammation; Japan; Liver; Mass Spectrometry; Metabolomics; Methionine; Mice; Mice, Inbred C3H; Principal Component Analysis; Purines; Pyrimidines; Triglycerides; Valine | 2016 |
High concentration of branched-chain amino acids promotes oxidative stress, inflammation and migration of human peripheral blood mononuclear cells via mTORC1 activation.
Topics: Amino Acids, Branched-Chain; Cell Movement; Humans; Inflammation; Insulin Resistance; Interleukin-6; Isoleucine; Leucine; Leukocytes, Mononuclear; Mechanistic Target of Rapamycin Complex 1; Mitochondria; NF-kappa B; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; TOR Serine-Threonine Kinases; Tumor Necrosis Factor-alpha; Valine | 2017 |
Excess salt causes cerebral neuronal apoptosis and inflammation in stroke-prone hypertensive rats through angiotensin II-induced NADPH oxidase activation.
Topics: Acetophenones; Angiotensin II; Animals; Antihypertensive Agents; Apoptosis; Astrocytes; Blood Pressure; Cerebral Cortex; Enzyme Activation; Enzyme Inhibitors; Humans; Hydralazine; Hypertension; Inflammation; Male; NADPH Oxidases; Neurons; Rats; Rats, Inbred SHR; Reactive Oxygen Species; Sodium Chloride; Stroke; Tetrazoles; Valine; Valsartan | 2008 |
Attenuation of inflammation and expansive remodeling by Valsartan alone or in combination with Simvastatin in high-risk coronary atherosclerotic plaques.
Topics: Animals; Antihypertensive Agents; Atherosclerosis; Blood Pressure; Coronary Artery Disease; Disease Models, Animal; Endothelium, Vascular; Inflammation; Lipids; Male; Rabbits; Risk; Simvastatin; Stress, Mechanical; Tetrazoles; Valine; Valsartan | 2009 |
High ambient glucose augments angiotensin II-induced proinflammatory gene mRNA expression in human mesangial cells: effects of valsartan and simvastatin.
Topics: Angiotensin II; Gene Expression Regulation; Glucose; Hemodynamics; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperglycemia; Inflammation; Kidney; Mesangial Cells; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Simvastatin; Tetrazoles; Valine; Valsartan | 2009 |
Valsartan protects pancreatic islets and adipose tissue from the inflammatory and metabolic consequences of a high-fat diet in mice.
Topics: Adipocytes; Adipose Tissue; Angiotensin II Type 1 Receptor Blockers; Animal Feed; Animals; Body Weight; Cytokines; Diabetes Mellitus, Type 2; Dietary Fats; Disease Models, Animal; Gene Expression; Glucose Intolerance; Inflammation; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Macrophages; Male; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Mitochondria; Tetrazoles; Valine; Valsartan | 2010 |
Considering amyloidosis in patients with clinically unresponsive vitreous inflammation (Oculoleptomeningeal amyloidosis in 3 individuals with transthyretin variant Tyr69His. Vol. 44[3]).
Topics: Adrenal Cortex Hormones; Amyloid Neuropathies, Familial; Drug Resistance; Eye Diseases; Genetic Variation; Glycine; Histidine; Humans; Inflammation; Point Mutation; Prealbumin; Tyrosine; Valine; Vitreous Body | 2010 |
Effects of the calcium sensitizer OR-1896, a metabolite of levosimendan, on post-infarct heart failure and cardiac remodelling in diabetic Goto-Kakizaki rats.
Topics: Acetamides; Animals; Biomarkers; Cardiac Volume; Cellular Senescence; Diabetes Mellitus, Type 2; Fibrosis; Heart Failure; Inflammation; Mitochondria, Heart; Myocardial Infarction; Myocytes, Cardiac; Pyridazines; Random Allocation; Rats; Tetrazoles; Time Factors; Valine; Valsartan; Vasodilator Agents; Ventricular Pressure | 2010 |
Local delivery of angiotensin II receptor blockers into the kidney passively attenuates inflammatory reactions during the early phases of streptozotocin-induced diabetic nephropathy through inhibition of calpain activity.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Calpain; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Inflammation; Kidney Glomerulus; Male; NF-kappa B; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Streptozocin; Tetrazoles; Transcription Factor RelA; Valine; Valsartan | 2010 |
The effect of intra-locus coeruleus injection of 17beta-estradiol on inflammatory pain modulation in male rat.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Disease Models, Animal; Estradiol; Estrogen Antagonists; Estrogens; Formaldehyde; Fulvestrant; Inflammation; Locus Coeruleus; Male; Microinjections; Pain; Rats; Rats, Sprague-Dawley; Valine | 2010 |
Effects of the Ala379Val polymorphism of lipoprotein-associated phospholipase A2 on thrombosis and inflammation in hypertensive patients.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Alanine; Fibrinogen; Gene Frequency; Genotype; Heterozygote; Humans; Hypertension; Inflammation; Logistic Models; Male; Middle Aged; Polymorphism, Single Nucleotide; Thrombosis; Valine | 2011 |
The crossroad of RAAS modulation, inflammation, and oxidative stress in dialysis patients: light at the end of the tunnel?
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Female; Humans; Inflammation; Male; Ramipril; Renal Dialysis; Tetrazoles; Valine; Valsartan | 2012 |
The synergistic effect of valsartan and LAF237 [(S)-1-[(3-hydroxy-1-adamantyl)ammo]acetyl-2-cyanopyrrolidine] on vascular oxidative stress and inflammation in type 2 diabetic mice.
Topics: Adamantane; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Apoptosis; Blood Glucose; Diabetes Mellitus, Type 2; Drug Synergism; Endothelial Cells; Endothelium, Vascular; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Hypoglycemic Agents; Inflammation; Intercellular Adhesion Molecule-1; Mice; NADPH Oxidases; Oxidative Stress; Pyrrolidines; Receptors, Glucagon; Tetrazoles; Valine; Valsartan; Vascular Cell Adhesion Molecule-1 | 2012 |
Inflammatory cytokines in vitro production are associated with Ala16Val superoxide dismutase gene polymorphism of peripheral blood mononuclear cells.
Topics: Alanine; Amino Acid Substitution; Cells, Cultured; Culture Media; Cytokines; Enzyme-Linked Immunosorbent Assay; Genotype; Glucose; Humans; Inflammation; Inflammation Mediators; Insulin; Interferon-gamma; Interleukin-1; Interleukin-10; Interleukin-6; Leukocytes, Mononuclear; Polymorphism, Genetic; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Valine | 2012 |
Differential efficacy of intrathecal NMDA receptor antagonists on inflammatory mechanical and thermal hyperalgesia in rats.
Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hyperalgesia; Inflammation; Injections, Spinal; Male; Motor Activity; Pain; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Treatment Outcome; Valine | 2003 |
Reduction of glycine receptor-mediated miniature inhibitory postsynaptic currents in rat spinal lamina I neurons after peripheral inflammation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Anesthetics, Local; Animals; Animals, Newborn; Bicuculline; Drug Interactions; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Freund's Adjuvant; GABA Antagonists; Glycine Agents; In Vitro Techniques; Inflammation; Male; Membrane Potentials; Neural Inhibition; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Spinal Cord; Strychnine; Synapses; Tetrodotoxin; Valine | 2003 |
A novel homozygous missense mutation in the GNE gene of a patient with quadriceps-sparing hereditary inclusion body myopathy associated with muscle inflammation.
Topics: Adult; Carbohydrate Epimerases; Diagnosis, Differential; DNA Mutational Analysis; Genetic Predisposition to Disease; Histocompatibility Antigens Class I; Homozygote; Humans; Inflammation; Iran; Male; Muscle Fibers, Skeletal; Muscle, Skeletal; Mutation, Missense; Myositis, Inclusion Body; Pedigree; Valine | 2003 |
Arginase pathway in human endothelial cells in pathophysiological conditions.
Topics: Antibodies, Antinuclear; Antibodies, Monoclonal; Arginase; Cell Cycle; Cell Proliferation; Endothelial Cells; Endothelium, Vascular; Gene Expression; Humans; Inflammation; Inflammation Mediators; Ki-67 Antigen; Nitric Oxide Synthase; Polyamines; RNA, Messenger; Up-Regulation; Valine | 2004 |
Peripheral NMDA receptor modulation of jaw muscle electromyographic activity induced by capsaicin injection into the temporomandibular joint of rats.
Topics: Analysis of Variance; Animals; Capsaicin; Disease Models, Animal; Dizocilpine Maleate; Electromyography; Excitatory Amino Acid Antagonists; Facial Pain; Inflammation; Jaw; Male; Muscle, Skeletal; Nociceptors; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex; Temporomandibular Joint; Valine | 2005 |
FMS receptor for M-CSF (CSF-1) is sensitive to the kinase inhibitor imatinib and mutation of Asp-802 to Val confers resistance.
Topics: Animals; Antineoplastic Agents; Aspartic Acid; Benzamides; Disease Progression; Dose-Response Relationship, Drug; Down-Regulation; Drug Resistance, Neoplasm; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Inflammation; Inhibitory Concentration 50; Macrophage Colony-Stimulating Factor; Mice; Mutation; Neoplasms; Oncogene Protein v-cbl; Phosphorylation; Piperazines; Protein Structure, Tertiary; Proto-Oncogene Proteins c-crk; Proto-Oncogene Proteins c-kit; Pyrimidines; Rats; Receptor Protein-Tyrosine Kinases; Receptor, Macrophage Colony-Stimulating Factor; Signal Transduction; Time Factors; Valine | 2006 |
In hepatocytes the regulation of NOS-2 activity at physiological L-arginine levels suggests a close link to the urea cycle.
Topics: Amino Acid Transport Systems, Basic; Animals; Arginase; Arginine; Base Sequence; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hepatocytes; Inflammation; Lysine; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Ornithine; Rats; Rats, Wistar; Urea; Valine | 2006 |
Eplerenone with valsartan effectively reduces atherosclerotic lesion by attenuation of oxidative stress and inflammation.
Topics: Aldosterone; Animals; Aorta; Atherosclerosis; Blood Pressure; Cells, Cultured; Chemokine CCL2; Cholesterol, Dietary; Diet, Atherogenic; Enzyme Activation; Eplerenone; Inflammation; Male; Mice; Muscle, Smooth, Vascular; NADPH Oxidases; Oxidative Stress; Spironolactone; Superoxides; Tetrazoles; Tumor Necrosis Factor-alpha; Valine; Valsartan | 2006 |
Angiotensin II type 1 receptor blockade attenuates in-stent restenosis by inhibiting inflammation and progenitor cells.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Biomarkers; Blood Pressure; Blood Vessels; Cell Differentiation; Constriction, Pathologic; Iliac Artery; Imidazoles; Inflammation; Inflammation Mediators; Isoenzymes; Macaca fascicularis; Male; Monocytes; Myocytes, Smooth Muscle; NADPH Oxidases; Oxidative Stress; Rabbits; Recurrence; Renin-Angiotensin System; Stem Cells; Stents; Tetrazoles; Tunica Intima; Valine; Valsartan | 2006 |
CCR5 blockade modulates inflammation and alloimmunity in primates.
Topics: Animals; Antibody Formation; Autoimmunity; CCR5 Receptor Antagonists; Cyclosporine; Disease Models, Animal; Graft Survival; Heart Transplantation; HIV Infections; Humans; Immunosuppressive Agents; Inflammation; Isoantibodies; Kidney Transplantation; Macaca fascicularis; Macrophages; Male; Pyrazoles; Stress, Physiological; T-Lymphocytes; Transplantation Tolerance; Transplantation, Homologous; Valine; Vascular Diseases | 2007 |
Effects of angiotensin II blockade on inflammation-induced alterations of pharmacokinetics and pharmacodynamics of calcium channel blockers.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Blotting, Western; C-Reactive Protein; Calcium Channel Blockers; Calcium Channels, L-Type; Drug Interactions; Inflammation; Male; Nitrendipine; Rats; Rats, Sprague-Dawley; Tetrazoles; Valine; Valsartan; Verapamil | 2008 |
Protective effects of an aptamer inhibitor of neutrophil elastase in lung inflammatory injury.
Topics: Animals; Capillary Permeability; Cell Movement; Immune Complex Diseases; Inflammation; Leukocyte Elastase; Lung; Male; Neutrophils; Oligodeoxyribonucleotides; Oligonucleotides; Rats; Rats, Inbred Strains; Serine Proteinase Inhibitors; Valine | 1997 |
Angiotensin II (AT(1)) receptor blockade reduces vascular tissue factor in angiotensin II-induced cardiac vasculopathy.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Genetically Modified; Antihypertensive Agents; Blood Coagulation Factors; Blood Pressure; Cell Line; CHO Cells; Coronary Disease; Coronary Vessels; Cricetinae; Extracellular Matrix Proteins; Heart Ventricles; Humans; Inflammation; Integrin alpha4beta1; Integrins; NF-kappa B; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Lymphocyte Homing; RNA, Messenger; Tetrazoles; Thromboplastin; Transcription Factor AP-1; Valine; Valsartan; Vascular Resistance | 2000 |
Peripheral group I metabotropic glutamate receptors modulate nociception in mice.
Topics: Animals; Chromones; Excitatory Amino Acid Antagonists; Glycine; Hindlimb; Hot Temperature; Immunohistochemistry; Inflammation; Male; Mice; Mice, Inbred C57BL; Neurons, Afferent; Pain; Pain Measurement; Pyridines; Receptors, Metabotropic Glutamate; Valine | 2001 |
Differential contributions of NMDA and non-NMDA receptors to spinal Fos expression evoked by superficial tissue and muscle inflammation in the rat.
Topics: Afferent Pathways; Animals; Cell Count; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glutamic Acid; Immunohistochemistry; Inflammation; Male; Muscle, Skeletal; Nociceptors; Pain; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Skin; Synaptic Transmission; Turpentine; Valine | 2001 |
Roles of angiotensin II type 2 receptor stimulation associated with selective angiotensin II type 1 receptor blockade with valsartan in the improvement of inflammation-induced vascular injury.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Cell Division; Chemokine CCL2; Femoral Artery; Inflammation; Interleukin-1; Interleukin-6; Leukocyte Common Antigens; Leukocytes; Macrophages; Male; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; RNA, Messenger; Tetrazoles; Tumor Necrosis Factor-alpha; Tunica Intima; Valine; Valsartan | 2001 |
The intrathecal administration of excitatory amino acid receptor antagonists selectively attenuated carrageenan-induced behavioral hyperalgesia in rats.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analgesics; Analysis of Variance; Animals; Behavior, Animal; Carrageenan; Dizocilpine Maleate; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Hyperalgesia; Inflammation; Injections, Spinal; Ketamine; Kynurenic Acid; Male; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Valine | 1992 |
Role of variant prealbumin in the pathogenesis of familial amyloidotic polyneuropathy: fate of normal and variant prealbumin in the circulation.
Topics: Amyloidosis; Animals; Genetic Variation; Humans; Inflammation; Male; Nervous System Diseases; Oxidation-Reduction; Photochemistry; Prealbumin; Rats; Rats, Inbred Strains; Reference Values; Tissue Distribution; Valine | 1989 |
The erythrocyte plasma distribution of amino acids in health and disease.
Topics: Acute Disease; Adolescent; Adult; Alanine; Amino Acids; Anemia, Hemolytic; Anemia, Pernicious; Bronchitis; Bronchopneumonia; Chromatography, Paper; Erythrocytes; Female; Glutamates; Glutamine; Glycine; Hepatitis; Humans; Hyperthyroidism; Infections; Inflammation; Isoleucine; Leucine; Male; Methionine; Neoplasms; Plasma; Pyelitis; Serine; Threonine; Valine | 1968 |
[Separation of low molecular weight ninhydrine positive substances in pleural punctates. Contribution to the problem of inflammation].
Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Chromatography; Chromatography, Gel; Electrophoresis; Glutamates; Glycine; Inflammation; Lysine; Paper; Peptides; Pleural Effusion; Rabbits; Serine; Trypan Blue; Valine | 1968 |