Compounds > valine

valine and Erythremia

valine has been researched along with Erythremia in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's13 (56.52)29.6817
2010's10 (43.48)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Álvarez-Larrán, A; Angona, A; Bellosillo, B; Besses, C; Camacho, L; Fernández-Rodríguez, C; Longarón, R; Senín, A1
Armstrong, SA; Austin, R; Breyfogle, LJ; Bruedigam, C; Ebert, BL; Heckl, D; Heidel, FH; Hill, GR; Kalaitzidis, D; Kuhn, CP; Lane, SW; Mullally, A; Poveromo, L; Purdon, A; Vu, T; Williams, DA1
Albano, F; Anelli, L; Brunetti, C; Casieri, P; Cellamare, A; Coccaro, N; Impera, L; Minervini, A; Minervini, CF; Ricco, A; Specchia, G; Tota, G; Zagaria, A1
Eisenhower, C; Erlich, P; Ferrari, A; Irvin-Barnwell, EA; Patel, MD; Roda, P; Tang, X1
Al-Kali, A; Cherry, M; Ghabache, B; Khawandanah, M; Ozer, H; Selby, G; Srour, S; Zhao, ZJ1
Baxter, EJ; Campbell, PJ; Godfrey, AL; Green, AR; Kent, DG; Massie, CE; Nangalia, J; Papaemmanuil, E1
Ambler, K; Casolari, DA; D'Andrea, RJ; Nguyen, T; Ross, DM; Tiong, IS; Van Velzen, MJ1
Babosova, O; Divoky, V; Korinek, V; Lanikova, L; Prchal, JT; Swierczek, S; Wang, L; Wheeler, DA1
Antonioli, E; Barosi, G; Bosi, A; Guglielmelli, P; Pieri, L; Vannucchi, AM1
Iványi, JL; Marton, E; Plander, M1
Hutchison, RE; Mohi, G; Yan, D1
Fu, X; Krantz, SB; Li, Q; Li, Z; Xing, S; Zhao, R; Zhao, ZJ1
Chao, MP; Durocher, JA; Gotlib, J; Jamieson, CH; Jones, C; Lay, M; Lilleberg, SL; Mariappan, MR; Weissman, IL; Zehnder, JL1
Hervé, F; Marie, I1
Fu, X; Ho, WT; Ishii, T; Li, Q; Li, Z; Xing, S; Xu, M; Zhao, ZJ1
Hasselbalch, HC; Kerndrup, GB; Larsen, TS; Pallisgaard, N1
Andrikovics, H; Csukly, Z; Halm, G; Király, V; Lovas, N; Lueff, S; Masszi, T; Mátrai, Z; Meggyesi, N; Mikala, G; Nahajevszky, S; Sipos, A; Szilvási, A; Tamáska, J; Tordai, A1
Bödör, C; Csernus, B; Csomor, J; Matolcsy, A; Rajnai, H; Reiniger, L; Szepesi, A; Timár, B1
Finke, C; Gilliland, DG; Hogan, WJ; Ketterling, RP; Lasho, TL; Mesa, RA; Pardanani, A; Tefferi, A1
Finke, CM; Gangat, N; Ketterling, RP; Knudson, RA; Lasho, TL; Li, CY; Pardanani, A; Strand, J; Tefferi, A1
Dirnhofer, S; Hao-Shen, H; Looser, R; Schwaller, J; Skoda, RC; Sobas, MA; Tiedt, R1
Cullen, DE; Doukas, J; Gilliland, DG; Gozo, M; Hood, JD; Kharas, MG; Ko, YD; Lee, BH; Leeman, DS; Levine, RL; Mak, CC; Martin, M; McDowell, EP; Moore, SA; Noronha, G; Okabe, R; Soll, RM; Tefferi, A; Wernig, G1
Abrahamsson, AE; Barroga, CF; Durocher, J; Geron, I; Gotlib, J; Hood, JD; Jamieson, CH; Kaushansky, K; Kavalerchik, E; Mak, CC; Noronha, G; Soll, RM; Tefferi, A1

Reviews

1 review(s) available for valine and Erythremia

ArticleYear
[Mutation of protein kinase JAK2 in polycythemia vera: new perspectives in physiopathology and therapy].
    La Revue de medecine interne, 2006, Volume: 27, Issue:6

    Topics: Amino Acid Substitution; Benzamides; Chromosomes, Human, Pair 9; Humans; Imatinib Mesylate; Janus Kinase 2; Phenylalanine; Piperazines; Point Mutation; Polycythemia Vera; Protein Kinase Inhibitors; Protein Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Pyrimidines; Valine

2006

Trials

1 trial(s) available for valine and Erythremia

ArticleYear
Erlotinib is not effective in patients with JAK2V617F-positive polycythemia vera.
    Annals of hematology, 2015, Volume: 94, Issue:4

    Topics: Adult; Aged; Amino Acid Substitution; Antineoplastic Agents; Drug-Related Side Effects and Adverse Reactions; Erlotinib Hydrochloride; Female; Humans; Janus Kinase 2; Male; Middle Aged; Phenylalanine; Polycythemia Vera; Quinazolines; Treatment Outcome; Valine

2015

Other Studies

21 other study(ies) available for valine and Erythremia

ArticleYear
Non-driver mutations in patients with JAK2V617F-mutated polycythemia vera or essential thrombocythemia with long-term molecular follow-up.
    Annals of hematology, 2018, Volume: 97, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Alleles; Amino Acid Substitution; Cell Transformation, Neoplastic; Cytogenetic Analysis; Disease Progression; Female; Follow-Up Studies; Gene Frequency; Humans; Janus Kinase 2; Male; Middle Aged; Mutation, Missense; Phenylalanine; Polycythemia Vera; Thrombocythemia, Essential; Valine

2018
Depletion of Jak2V617F myeloproliferative neoplasm-propagating stem cells by interferon-α in a murine model of polycythemia vera.
    Blood, 2013, May-02, Volume: 121, Issue:18

    Topics: Amino Acid Substitution; Animals; Apoptosis; Cell Proliferation; Disease Models, Animal; Hematologic Neoplasms; Humans; Interferon-alpha; Janus Kinase 2; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutant Proteins; Neoplastic Stem Cells; Phenylalanine; Polycythemia Vera; Valine

2013
IgG-lymphoplasmacytic lymphoma following polycythemia vera: JAK2 V617F and MYD88 L265P mutations separated in the same house.
    Annals of hematology, 2014, Volume: 93, Issue:9

    Topics: Aged; Amino Acid Substitution; Humans; Immunoglobulin G; Janus Kinase 2; Leucine; Male; Mutation, Missense; Myeloid Differentiation Factor 88; Phenylalanine; Polycythemia Vera; Proline; Valine; Waldenstrom Macroglobulinemia

2014
Determination of accuracy of polycythemia vera diagnoses and use of the JAK2V617F test in the diagnostic scheme.
    Annals of hematology, 2014, Volume: 93, Issue:9

    Topics: Amino Acid Substitution; Diagnostic Errors; DNA Mutational Analysis; Genetic Testing; Humans; Janus Kinase 2; Mutation, Missense; Myeloproliferative Disorders; Phenylalanine; Polycythemia Vera; Registries; Retrospective Studies; Sensitivity and Specificity; Valine

2014
Nongenetic stochastic expansion of JAK2V617F-homozygous subclones in polycythemia vera?
    Blood, 2014, Nov-20, Volume: 124, Issue:22

    Topics: Amino Acid Substitution; Clone Cells; DNA Mutational Analysis; Homozygote; Humans; Janus Kinase 2; Phenylalanine; Polycythemia Vera; Stochastic Processes; Valine

2014
Masked polycythaemia vera is genetically intermediate between JAK2V617F mutated essential thrombocythaemia and overt polycythaemia vera.
    Blood cancer journal, 2016, 08-19, Volume: 6, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Asymptomatic Diseases; Cohort Studies; Disease Progression; Female; Genetic Predisposition to Disease; Humans; Janus Kinase 2; Male; Middle Aged; Mutation, Missense; Phenylalanine; Polycythemia Vera; Polymorphism, Single Nucleotide; Prodromal Symptoms; Thrombocythemia, Essential; Valine

2016
Coexistence of gain-of-function JAK2 germ line mutations with JAK2V617F in polycythemia vera.
    Blood, 2016, 11-03, Volume: 128, Issue:18

    Topics: Amino Acid Substitution; Cells, Cultured; Cohort Studies; DNA Mutational Analysis; Germ-Line Mutation; Humans; Janus Kinase 2; Mutation, Missense; Phenylalanine; Polycythemia Vera; Polymorphism, Single Nucleotide; Valine

2016
JAK2V617F mutational status and allele burden have little influence on clinical phenotype and prognosis in patients with post-polycythemia vera and post-essential thrombocythemia myelofibrosis.
    Haematologica, 2009, Volume: 94, Issue:1

    Topics: Adult; Aged; Alleles; Female; Humans; Janus Kinase 2; Male; Middle Aged; Mutation; Phenotype; Polycythemia Vera; Prognosis; Thrombocythemia, Essential; Valine

2009
[Significance of the JAK2V617F mutation in patients with chronic myeloproliferative neoplasia].
    Orvosi hetilap, 2011, Nov-06, Volume: 152, Issue:45

    Topics: Adult; Aged; Bone Marrow Neoplasms; Chronic Disease; Female; Humans; Janus Kinase 2; Male; Middle Aged; Mutation; Myeloproliferative Disorders; Phenylalanine; Polycythemia Vera; Polymerase Chain Reaction; Predictive Value of Tests; Primary Myelofibrosis; Retrospective Studies; Signal Transduction; Thrombocythemia, Essential; Thrombosis; Valine

2011
Critical requirement for Stat5 in a mouse model of polycythemia vera.
    Blood, 2012, Apr-12, Volume: 119, Issue:15

    Topics: Amino Acid Substitution; Animals; Disease Models, Animal; Gene Knock-In Techniques; Genes, Lethal; HEK293 Cells; Humans; Janus Kinase 2; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation, Missense; Phenylalanine; Polycythemia Vera; STAT5 Transcription Factor; Valine

2012
Identification of an acquired JAK2 mutation in polycythemia vera.
    The Journal of biological chemistry, 2005, Jun-17, Volume: 280, Issue:24

    Topics: Amino Acid Sequence; Animals; Base Sequence; Cytokines; DNA Mutational Analysis; DNA, Complementary; Erythropoietin; HeLa Cells; Heterozygote; Humans; Immunoblotting; Janus Kinase 2; Molecular Sequence Data; Mutation; Phenylalanine; Point Mutation; Polycythemia Vera; Polymerase Chain Reaction; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptors, Erythropoietin; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Signal Transduction; Transfection; Tyrosine; Valine

2005
The JAK2 V617F mutation occurs in hematopoietic stem cells in polycythemia vera and predisposes toward erythroid differentiation.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Apr-18, Volume: 103, Issue:16

    Topics: ADP-ribosyl Cyclase 1; Amino Acid Substitution; Antigens, CD34; Erythroid Precursor Cells; Hematopoiesis; Hematopoietic Stem Cells; Humans; Janus Kinase 2; Phenylalanine; Point Mutation; Polycythemia Vera; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Thy-1 Antigens; Tyrphostins; Valine

2006
Erlotinib effectively inhibits JAK2V617F activity and polycythemia vera cell growth.
    The Journal of biological chemistry, 2007, Feb-09, Volume: 282, Issue:6

    Topics: Amino Acid Substitution; Animals; Cell Line, Tumor; Cell Proliferation; Drug Delivery Systems; Enzyme Activation; Erlotinib Hydrochloride; Growth Inhibitors; Hematopoietic Stem Cells; Humans; Janus Kinase 2; Jurkat Cells; Mice; Phenylalanine; Polycythemia Vera; Protein Kinase Inhibitors; Quinazolines; Valine

2007
A der(18)t(9;18)(p13;p11) and a der(9;18)(p10;q10) in polycythemia vera associated with a hyperproliferative phenotype in transformation to postpolycythemic myelofibrosis.
    Cancer genetics and cytogenetics, 2007, Jan-15, Volume: 172, Issue:2

    Topics: Aged; Cell Proliferation; Cell Transformation, Neoplastic; Chromosomes, Human, Pair 18; Chromosomes, Human, Pair 9; Female; Humans; Janus Kinase 2; Male; Middle Aged; Phenotype; Phenylalanine; Polycythemia Vera; Primary Myelofibrosis; Translocation, Genetic; Valine

2007
[Role of the activating mutation Val617Phe of Janus kinase 2 gene in myeloproliferative diseases and significance of its detection].
    Orvosi hetilap, 2007, Feb-04, Volume: 148, Issue:5

    Topics: Adult; Aged; Biopsy; Bone Marrow; Female; Gene Expression Regulation; Gene Frequency; Humans; Janus Kinase 2; Male; Middle Aged; Myeloproliferative Disorders; Phenotype; Phenylalanine; Point Mutation; Polycythemia Vera; Polymerase Chain Reaction; Primary Myelofibrosis; Thrombocytosis; Valine

2007
[Novel method in diagnosis of chronic myeloproliferative disorders--detection of JAK2 mutation].
    Orvosi hetilap, 2006, Nov-12, Volume: 147, Issue:45

    Topics: Alleles; Amino Acid Sequence; Base Sequence; Biomarkers, Tumor; Genetic Markers; Humans; Janus Kinase 2; Leukemia; Molecular Sequence Data; Myeloproliferative Disorders; Phenylalanine; Point Mutation; Polycythemia Vera; Polymerase Chain Reaction; Primary Myelofibrosis; Signal Transduction; Thrombocytopenia; Valine

2006
Extending Jak2V617F and MplW515 mutation analysis to single hematopoietic colonies and B and T lymphocytes.
    Stem cells (Dayton, Ohio), 2007, Volume: 25, Issue:9

    Topics: Amino Acid Substitution; B-Lymphocytes; Base Sequence; Cells, Cultured; Clone Cells; DNA Mutational Analysis; Hematopoiesis; Humans; Janus Kinase 2; Point Mutation; Polycythemia Vera; Primary Myelofibrosis; Receptors, Thrombopoietin; T-Lymphocytes; Tryptophan; Valine

2007
Cytogenetic studies at diagnosis in polycythemia vera: clinical and JAK2V617F allele burden correlates.
    European journal of haematology, 2008, Volume: 80, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alleles; Amino Acid Substitution; Bone Marrow Cells; Chromosome Aberrations; Disease-Free Survival; Female; Humans; Janus Kinase 2; Male; Middle Aged; Phenylalanine; Polycythemia Vera; Prognosis; Retrospective Studies; Valine

2008
Ratio of mutant JAK2-V617F to wild-type Jak2 determines the MPD phenotypes in transgenic mice.
    Blood, 2008, Apr-15, Volume: 111, Issue:8

    Topics: Animals; Colony-Forming Units Assay; Granulocytes; Hematopoiesis, Extramedullary; Humans; Hyperplasia; Integrases; Janus Kinase 2; Megakaryocytes; Mice; Mice, Transgenic; Mutant Proteins; Myeloproliferative Disorders; Phenotype; Phenylalanine; Polycythemia Vera; Primary Myelofibrosis; Recombination, Genetic; Thrombocythemia, Essential; Transgenes; Valine

2008
Efficacy of TG101348, a selective JAK2 inhibitor, in treatment of a murine model of JAK2V617F-induced polycythemia vera.
    Cancer cell, 2008, Volume: 13, Issue:4

    Topics: Amino Acid Substitution; Animals; Bone Marrow Transplantation; Cell Line, Tumor; Colony-Forming Units Assay; Disease Models, Animal; Endpoint Determination; Flow Cytometry; Hematopoietic System; Humans; Janus Kinase 2; Mice; Mice, Inbred C57BL; Phenylalanine; Polycythemia Vera; Protein Kinase Inhibitors; Pyrrolidines; Signal Transduction; Sulfonamides; Survival Rate; Treatment Outcome; Valine

2008
Selective inhibition of JAK2-driven erythroid differentiation of polycythemia vera progenitors.
    Cancer cell, 2008, Volume: 13, Issue:4

    Topics: Adult; Aged; Amino Acid Substitution; Animals; Base Sequence; Cell Differentiation; Erythroid Precursor Cells; Female; Humans; Janus Kinase 2; Male; Mice; Middle Aged; Molecular Sequence Data; Phenylalanine; Polycythemia Vera; Protein Kinase Inhibitors; Signal Transduction; Stem Cell Transplantation; Valine

2008