valine and Disease Models, Animal

Topics: Adipocytes; Adiponectin; Aged; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta; Apolipoproteins E; Biomarkers; Cardiovascular Diseases; Disease Models, Animal; Female; Fibrinolysis; Humans; Hypertension; Japan; Male; Metabolic Syndrome; Mice; Mice, Knockout; Middle Aged; Plasminogen Activator Inhibitor 1; Prospective Studies; Receptor, Angiotensin, Type 1; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan

Topics: Amino Acids, Branched-Chain; Animals; Anthrax; Bacillus anthracis; Bacterial Proteins; Cattle; Disease Models, Animal; Isoleucine; Mammals; Membrane Transport Proteins; Mice; Valine; Virulence

Topics: Animals; Disease Models, Animal; Fatty Acid-Binding Proteins; Heterocyclic Compounds, 2-Ring; Imiquimod; Inflammation; Keratinocytes; Mice; Mice, Inbred BALB C; Neoplasm Proteins; Psoriasis; Skin; STAT3 Transcription Factor; Valine

Topics: Alanine; Animals; Anticonvulsants; Asparagine; Citrates; Creatine; Creatinine; Disease Models, Animal; Epilepsy; Glucose; Glutamates; Isoleucine; Ketone Bodies; Lactates; Leucine; Pentylenetetrazole; Pyruvates; Rats; Seizures; Succinates; Valine

Topics: Alanine; Animals; Asparagine; Aspartic Acid; Cytokines; Disease Models, Animal; Glucose; Histidine; Imiquimod; Interleukin-17; Interleukin-23; Interleukin-8; Magnetic Resonance Spectroscopy; Mice; Moxibustion; Psoriasis; Skin; Taurine; Triglycerides; Valine

Topics: Animals; Arginine; Bile Acids and Salts; Bile Pigments; Disease Models, Animal; Hippurates; Histidine; Hormones; Humans; Malaria, Cerebral; Mice; Ornithine; Phenylalanine; Plasmodium berghei; Sphingolipids; Valine

Topics: Animals; Disease Models, Animal; Edema; Feeding Behavior; Indazoles; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Molecular Structure; Rats; Receptors, Cannabinoid; Rimonabant; Valine; Zymosan

Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Astrocytes; Blood-Brain Barrier; Brain; Cerebral Amyloid Angiopathy; Disease Models, Animal; Male; Mice, Inbred C57BL; Mice, Transgenic; Valine

Topics: Alzheimer Disease; Animals; Arginase; Disease Models, Animal; Gene Expression Regulation; Hippocampus; Male; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Neurogenesis; Valine

Topics: Animals; Antihypertensive Agents; Blood Pressure; Creatinine; Disease Models, Animal; Diuresis; Hypertension; Male; Rats; Rats, Wistar; Urea; Uric Acid; Valine

Topics: Animals; Antiviral Agents; Benzimidazoles; Carbamates; Cost-Benefit Analysis; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Fluorenes; Hepacivirus; Hepatitis C, Chronic; Imidazoles; Liver Cirrhosis; Models, Animal; Pyrrolidines; Ribavirin; Sofosbuvir; Swine; Valine

Topics: Animals; Antiviral Agents; Carbamates; Disease Models, Animal; Dogs; Drug Therapy, Combination; Genotype; Hepacivirus; Hepatitis C; Humans; Imidazoles; Male; Mice; Pyrrolidines; Rats; Rats, Sprague-Dawley; Valine; Viral Envelope Proteins; Virus Internalization

Topics: Animals; Animals, Newborn; Disease Models, Animal; Humans; Infant, Newborn; Rats; Rats, Sprague-Dawley; Spasms, Infantile; Valine

Topics: Angiogenesis Inhibitors; Animals; Biomarkers; Blotting, Western; Burns, Chemical; Corneal Neovascularization; Disease Models, Animal; Epithelium, Corneal; Extracellular Signal-Regulated MAP Kinases; Eye Burns; Eye Proteins; Humans; Immunoprecipitation; Lymphangiogenesis; Mice; Mice, Inbred C57BL; Phosphorylation; Pyrrolidines; Real-Time Polymerase Chain Reaction; Sodium Hydroxide; Valine

Topics: Action Potentials; Animals; Brain Injuries, Traumatic; Diffuse Axonal Injury; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glutamate Decarboxylase; Inhibitory Postsynaptic Potentials; Luminescent Proteins; Male; Mice; Mice, Transgenic; Neocortex; Nerve Tissue Proteins; Neural Inhibition; Neural Pathways; Parvalbumins; Quinoxalines; Valine; Vesicular Inhibitory Amino Acid Transport Proteins

Topics: Analgesics; Animals; Disease Models, Animal; Female; Formaldehyde; Mice; Pain; Valine

Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Arousal; Brain Mapping; Brain Waves; Cerebral Cortex; Disease Models, Animal; Electroencephalography; Fourier Analysis; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Phenylalanine; Valine

Topics: Analgesics; Animals; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Antagonists; Hyperalgesia; Inhibitory Postsynaptic Potentials; Male; Medulla Oblongata; Neurons; Pain Measurement; Pain Threshold; Pain, Postoperative; Quinoxalines; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetrodotoxin; Thalidomide; Valine

Topics: Alanine; Animals; Antibodies, Monoclonal; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Drug Stability; Female; Humans; Hydrophobic and Hydrophilic Interactions; Immunoconjugates; Oligopeptides; Valine; Xenograft Model Antitumor Assays

Topics: Acoustic Stimulation; Analysis of Variance; Animals; Apomorphine; Brain-Derived Neurotrophic Factor; Corticosterone; Disease Models, Animal; Dizocilpine Maleate; Dopamine Agonists; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Genotype; Humans; Methionine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Polymorphism, Genetic; Prepulse Inhibition; Stress, Psychological; Valine

Topics: Animals; Choice Behavior; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Food Preferences; Impulsive Behavior; Male; Mental Disorders; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motivation; Mutation; Reinforcement, Psychology; Sucrose; Sweetening Agents; Valine

Topics: Aged; Animals; Antiviral Agents; Benzazepines; Carbamates; Disease Models, Animal; Female; Gene Expression Regulation; Hepacivirus; Hepatitis C, Chronic; Hepatocytes; Humans; Imidazoles; Immunity, Innate; Indoles; Inflammation; Isoquinolines; Liver; Male; Mice; Middle Aged; Pyrrolidines; Sulfonamides; Valine

Topics: Animals; Anxiety; Cerebral Cortex; Conditioning, Classical; Disease Models, Animal; Disks Large Homolog 4 Protein; Excitatory Amino Acid Agents; Exploratory Behavior; Fear; Glutamic Acid; Long-Term Potentiation; Male; Maze Learning; Membrane Potentials; Mice; Mice, Inbred C57BL; Neurons; Receptors, Kainic Acid; Synaptosomal-Associated Protein 25; Valine

Topics: Action Potentials; Animals; Animals, Newborn; Channelrhodopsins; Disease Models, Animal; Excitatory Amino Acid Antagonists; Functional Laterality; Glutamic Acid; Hippocampus; Male; Nerve Net; Neural Inhibition; Neural Pathways; Neuralgia; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetrodotoxin; Thalamus; Valine

Topics: A549 Cells; Amino Acid Substitution; Animals; Chlorocebus aethiops; Cloning, Molecular; Disease Models, Animal; DNA, Complementary; Evolution, Molecular; Genome, Viral; Humans; Methionine; Mice; Promoter Regions, Genetic; Valine; Vero Cells; Viral Nonstructural Proteins; Virus Replication; Zika Virus; Zika Virus Infection

Topics: Animals; Body Weight; Computational Biology; Disease Models, Animal; Doxorubicin; Fatty Acids, Monounsaturated; Glomerulosclerosis, Focal Segmental; Male; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred BALB C; Pyridoxine; Valine; Vanillic Acid

Topics: Administration, Oral; Animals; Arginine; Bleomycin; Disease Models, Animal; Disease Progression; Drug Therapy, Combination; Intraepithelial Lymphocytes; Lung; Male; Mice; Pulmonary Fibrosis; T-Lymphocytes, Regulatory; Th17 Cells; Valine

Topics: Animals; Area Under Curve; Biomarkers; Disease Models, Animal; Disease Progression; Early Diagnosis; Heart Failure; Leucine; Machine Learning; Male; Metabolome; Metabolomics; Myocardial Infarction; Rats; Rats, Sprague-Dawley; ROC Curve; Valine

Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Adrenergic Agents; Anesthetics, Local; Animals; Animals, Newborn; Bicuculline; Biophysics; Calcium; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Antagonists; Feedback, Physiological; GABA Antagonists; gamma-Aminobutyric Acid; Green Fluorescent Proteins; In Vitro Techniques; Lidocaine; Lysine; Male; Mice; Mice, Transgenic; Monte Carlo Method; Neostriatum; Neural Inhibition; Neural Pathways; Neurons; Oxidopamine; Parkinsonian Disorders; Patch-Clamp Techniques; Pyridazines; Rats; Rats, Wistar; Reaction Time; Receptors, Dopamine D1; Receptors, Dopamine D2; Synaptic Transmission; Time Factors; Valine

Topics: Amino Acid Substitution; Animals; Apoptosis; Cell Proliferation; Disease Models, Animal; Hematologic Neoplasms; Humans; Interferon-alpha; Janus Kinase 2; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutant Proteins; Neoplastic Stem Cells; Phenylalanine; Polycythemia Vera; Valine

Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Animals, Newborn; Cells, Cultured; Cerebral Cortex; Channelrhodopsins; Corpus Striatum; Corticosterone; Disease Models, Animal; DNA Breaks, Double-Stranded; Excitatory Amino Acid Antagonists; Exploratory Behavior; Gene Expression Regulation; Hippocampus; Histones; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Photic Stimulation; Quinoxalines; Reactive Oxygen Species; Stress, Physiological; tau Proteins; Valine

Topics: Acute Kidney Injury; Angiotensin Receptor Antagonists; Animals; Constriction, Pathologic; Disease Models, Animal; Female; Glomerular Filtration Rate; Hemodynamics; Kidney; Microcirculation; Oxidative Stress; Receptors, Angiotensin; Renal Artery Obstruction; Swine; Tetrazoles; Valine; Valsartan

Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Atrial Fibrillation; Disease Models, Animal; Dogs; Tetrazoles; TRPC Cation Channels; Valine; Valsartan

Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Disease Models, Animal; Fibroblasts; Fibrosis; Gene Expression; Graft vs Host Disease; Histocompatibility Testing; Humans; Imidazoles; Lacrimal Apparatus; Liver; Lung; Male; Mice; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan

Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Blood Glucose; Blood Pressure; Bone Morphogenetic Proteins; Carrier Proteins; Diabetes Mellitus, Type 2; Disease Models, Animal; Hyperglycemia; Male; Mice; Mice, Mutant Strains; Reactive Oxygen Species; Tetrazoles; Valine; Valsartan; Vasculitis

Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amygdala; Animals; Anxiety; Bacterial Proteins; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Channelrhodopsins; Disease Models, Animal; Excitatory Amino Acid Antagonists; Exploratory Behavior; Halorhodopsins; Hippocampus; In Vitro Techniques; Luminescent Proteins; Male; Maze Learning; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neural Pathways; Neurons; Sodium Channel Blockers; Synapses; Tetrodotoxin; Valine

Topics: Acids, Acyclic; Aminoisobutyric Acids; Animals; Blood-Brain Barrier; Brain; Disease Models, Animal; Humans; Isoleucine; Large Neutral Amino Acid-Transporter 1; Methylation; Mice; Mice, Transgenic; Molecular Targeted Therapy; Organ Specificity; Phenylalanine; Phenylketonurias; Protein Conformation; Protein Folding; Valine

Topics: Adamantane; Adiponectin; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Glucose; Cytokines; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Drug Therapy, Combination; Fatty Liver; Homeodomain Proteins; Inflammation; Insulin; Insulin Resistance; Insulin Secretion; Insulin-Secreting Cells; Mice; Mice, Inbred C57BL; Nitriles; Phlorhizin; Pyrrolidines; Tetrazoles; Trans-Activators; Valine; Valsartan; Vildagliptin

Topics: Amides; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzazepines; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Disease Models, Animal; Down-Regulation; Fumarates; Kallikreins; Kininogens; Kinins; Mice; Mice, Knockout; Myocytes, Cardiac; Receptor, Angiotensin, Type 1; Renin; Renin-Angiotensin System; Tetrazoles; Ultrasonography; Valine; Valsartan

Topics: Acrylic Resins; Administration, Cutaneous; Animals; Antihypertensive Agents; Blood Pressure; Chemistry, Pharmaceutical; Cyclohexanols; Disease Models, Animal; Eucalyptol; Gels; Monoterpenes; Rats; Skin; Tetrazoles; Valine; Valsartan

Topics: Animals; Animals, Newborn; Avoidance Learning; Cognition Disorders; Complement C3; Disease Models, Animal; Dizocilpine Maleate; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Gene Expression Regulation; Hippocampus; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Net; Neurons; Picrotoxin; Synapses; Ultrasonography; Valine

Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Brain Stem; Disease Models, Animal; Excitatory Amino Acid Antagonists; Female; HEK293 Cells; Humans; In Vitro Techniques; Male; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Mutation; Neurons; Presynaptic Terminals; Receptors, Glycine; Sodium Channel Blockers; Spinal Cord; Stiff-Person Syndrome; Tetrodotoxin; Valine

Topics: Administration, Oral; Angiotensin II; Animals; Antioxidants; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Hypertrophy, Left Ventricular; Isoflavones; Male; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocytes, Cardiac; NF-kappa B; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Reactive Oxygen Species; Signal Transduction; Tetrazoles; Ultrasonography; Valine; Valsartan; Ventricular Remodeling

Topics: Acetylcholinesterase; Aluminum Chloride; Aluminum Compounds; Animals; Cerebral Cortex; Chlorides; Cognition Disorders; Dementia; Disease Models, Animal; Galactose; Glutathione Peroxidase; Hippocampus; Malondialdehyde; Maze Learning; Memory Disorders; Mice; Nootropic Agents; Oxidative Stress; Random Allocation; Superoxide Dismutase; Tetrazoles; Valine; Valsartan

Topics: Animals; Apoptosis; Benzophenones; Carcinoma, Hepatocellular; Cell Line, Tumor; Disease Models, Animal; Doxorubicin; Drug Evaluation, Preclinical; Drug Synergism; Humans; Liver Neoplasms; Mice; Necrosis; Neovascularization, Pathologic; Tumor Burden; Valine; Xenograft Model Antitumor Assays

Topics: Animals; Cell Survival; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Disks Large Homolog 4 Protein; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Gene Expression Regulation; Guanylate Kinases; Hippocampus; Infarction, Middle Cerebral Artery; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Nervous System Diseases; Proto-Oncogene Proteins c-fyn; Receptors, N-Methyl-D-Aspartate; Time Factors; Valine

Topics: Amyloid Neuropathies, Familial; Animals; Disease Models, Animal; Female; Functional Laterality; Ganglia, Spinal; Gene Expression Regulation; Humans; Inflammation; Locomotion; Male; Methionine; Mice; Mice, Transgenic; Mutation; Pain Measurement; Prealbumin; Schwann Cells; Sciatic Neuropathy; Time Factors; Valine

Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Disease Models, Animal; Electroretinography; Female; Fluorescent Antibody Technique, Indirect; Microglia; Microscopy, Confocal; Oxygen; Photic Stimulation; Photoreceptor Cells, Vertebrate; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Retinal Neovascularization; Retinal Vessels; Retinopathy of Prematurity; Tetrazoles; Valine; Valsartan

Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Thoracic; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Gene Expression Regulation; Male; Muscle, Smooth, Vascular; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Reverse Transcriptase Polymerase Chain Reaction; RNA; Signal Transduction; Tetrazoles; Valine; Valsartan; Vascular Remodeling; Vascular System Injuries

Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Cognition; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Freund's Adjuvant; Gyrus Cinguli; In Vitro Techniques; Mice; Mice, Inbred C57BL; Neurons; Patch-Clamp Techniques; Peripheral Nervous System Diseases; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Valine

Topics: Action Potentials; Analysis of Variance; Animals; Anticonvulsants; Benzodiazepines; Carbamazepine; Cells, Cultured; Disease Models, Animal; Epilepsy, Frontal Lobe; Leucine; Mice; Mice, Transgenic; Mutation; Nerve Net; Neurons; Receptors, Nicotinic; Transfection; Valine

Topics: Animals; Animals, Newborn; Carrier Proteins; Corpus Striatum; Cricetinae; Cytoskeletal Proteins; Disease Models, Animal; Dose-Response Relationship, Drug; Dystonia; Dystonin; Excitatory Amino Acid Antagonists; Female; Long-Term Potentiation; Magnesium; Male; Mutation; Nerve Tissue Proteins; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Severity of Illness Index; Time Factors; Valine

Topics: Amino Acid Substitution; Animals; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; Gene Expression Regulation, Leukemic; Glycine; GTP Phosphohydrolases; Humans; Leukemia, Myeloid, Acute; Membrane Proteins; Mice; Mice, SCID; Oncogenes; Transcriptome; Tumor Cells, Cultured; Valine

Topics: Animals; Animals, Newborn; Biophysics; Brain Injuries; Cerebral Cortex; Disease Models, Animal; Electric Stimulation; Electroencephalography; Epilepsy; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Neurons; Patch-Clamp Techniques; Quinoxalines; Rats; Rats, Sprague-Dawley; Valine

Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animal Feed; Animals; Disease Models, Animal; Female; Glomerular Filtration Rate; Kidney; Male; Microdialysis; Nephrectomy; Protons; Rats; Rats, Wistar; Sodium Bicarbonate; Tetrazoles; Valine; Valsartan

Topics: Analysis of Variance; Animals; Cold Temperature; Disease Models, Animal; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hypothalamic Area, Lateral; Male; N-Methylaspartate; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Restraint, Physical; Stomach Ulcer; Valine

Topics: 14-3-3 Proteins; Animals; Animals, Newborn; Antidepressive Agents; Cells, Cultured; Disease Models, Animal; Excitatory Amino Acid Antagonists; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Immunoprecipitation; Male; Mice; Neurons; Phenols; Piperidines; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; RNA, Messenger; Stress, Psychological; Swimming; Synaptosomes; Transduction, Genetic; Valine

Topics: Amino Acid Substitution; Animals; Bone Marrow; Bone Marrow Neoplasms; Disease Models, Animal; Disease Progression; Gene Deletion; Hematopoietic Stem Cells; Janus Kinase 2; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myeloproliferative Disorders; Phenylalanine; STAT3 Transcription Factor; Thrombocytosis; Valine

Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Dexamethasone; Disease Models, Animal; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glucocorticoids; Hippocampus; Hormone Antagonists; Humans; Memory Disorders; Memory, Episodic; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mifepristone; Mutation; Neuronal Plasticity; Quinoxalines; Receptors, Glucocorticoid; Recognition, Psychology; Valine

Topics: 2-Aminopurine; Acyclovir; Administration, Oral; Administration, Topical; Animals; Antiviral Agents; Disease Models, Animal; DNA Copy Number Variations; DNA, Viral; Epithelium, Corneal; Eye Infections, Viral; Famciclovir; Female; Herpesvirus 1, Human; Keratitis, Herpetic; Mice; Mice, Inbred C57BL; Real-Time Polymerase Chain Reaction; Tears; Trigeminal Nerve; Valacyclovir; Valine

Topics: Animals; Arthritis, Experimental; Autoimmune Diseases; Disease Models, Animal; Edema; Female; Heterocyclic Compounds, 2-Ring; Humans; Hypersensitivity, Delayed; Inflammation; Janus Kinase 1; Janus Kinase 2; Janus Kinase 3; Male; Mice; Protein Kinase Inhibitors; Rats; Valine

Topics: Animals; Biotinylation; Disease Models, Animal; Excitatory Amino Acid Antagonists; GABA Agonists; Gene Expression Regulation; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Isoxazoles; Male; Muscarinic Agonists; Neurons; Pilocarpine; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Status Epilepticus; Valine

Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Actins; Action Potentials; Animals; Dendrites; Disease Models, Animal; Excitatory Amino Acid Antagonists; Exploratory Behavior; GABAergic Neurons; Glutamate Decarboxylase; Hippocampus; Male; Maze Learning; Mice; Mice, Transgenic; Parvalbumins; Phenotype; Reflex, Startle; Schizophrenia; Somatostatin; Valine

Topics: Animals; Atorvastatin; Blotting, Western; Cells, Cultured; Disease Models, Animal; Endoglin; Fibrosis; Gene Expression Regulation; Hemodynamics; Heptanoic Acids; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Male; MicroRNAs; Muscle Cells; Myocardial Infarction; Polymerase Chain Reaction; Pyrroles; Random Allocation; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Tetrazoles; Valine; Valsartan; Ventricular Remodeling

Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Disease Models, Animal; Enalapril; Epinephrine; Female; Male; Oxidative Stress; Rats; Rats, Long-Evans; Tetrazoles; Valine; Valsartan

Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Blotting, Western; Coronary Circulation; Disease Models, Animal; Gene Expression Regulation; Male; Myocardial Reperfusion Injury; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptor, Angiotensin, Type 2; RNA, Messenger; Tetrazoles; Up-Regulation; Valine; Valsartan

Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Afferent Pathways; Animals; Channelrhodopsins; Disease Models, Animal; Dopaminergic Neurons; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Excitatory Amino Acid Antagonists; GABAergic Neurons; Glutamate Decarboxylase; Male; Morphine; Narcotics; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Time Factors; Valine; Ventral Tegmental Area

Topics: Alcohol Drinking; Alcoholism; Alleles; Animals; Benzamides; Brain-Derived Neurotrophic Factor; Compulsive Behavior; Disease Models, Animal; Methionine; Mice; Mice, Transgenic; Polymorphism, Single Nucleotide; Protein-Tyrosine Kinases; Receptor, trkB; Valine

Topics: Animals; Biological Transport; Carbon Radioisotopes; Cell Line, Tumor; Disease Models, Animal; Drug Stability; Humans; Lung Neoplasms; Male; Mice; Positron-Emission Tomography; Tissue Distribution; Valine

Topics: Acyclovir; Administration, Oral; Animals; Antiviral Agents; Artemisinins; Artesunate; Brain; Cytokines; Disease Models, Animal; Drug Therapy, Combination; Encephalitis, Herpes Simplex; Female; Immunologic Factors; Injections, Intraperitoneal; Mice, Inbred BALB C; Sirolimus; Survival Analysis; Treatment Outcome; Valacyclovir; Valine; Viral Load

Topics: Animals; Animals, Genetically Modified; Carcinoma; Carcinoma, Papillary; Cell-Penetrating Peptides; Disease Models, Animal; Fluorescence; Glutamic Acid; Laryngoscopy; Larynx; Mice; Molecular Targeted Therapy; Proto-Oncogene Proteins B-raf; Staining and Labeling; Thyroid Cancer, Papillary; Thyroid Neoplasms; Thyroidectomy; Treatment Outcome; Valine; Video Recording; Vocal Cords

Topics: Animals; Animals, Newborn; Brain; Brain-Derived Neurotrophic Factor; Calcium Channel Blockers; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Female; Gene Expression Regulation, Developmental; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Tetrodotoxin; Transcription Factors; Valine; Visual Cortex

Topics: Animals; Anorexia Nervosa; Behavior, Animal; Brain-Derived Neurotrophic Factor; Caloric Restriction; Disease Models, Animal; Feeding Behavior; Female; Gene-Environment Interaction; Genetic Predisposition to Disease; Methionine; Mice; Polymorphism, Single Nucleotide; Risk Factors; Severity of Illness Index; Stress, Psychological; Valine

Topics: Animals; Brain-Derived Neurotrophic Factor; Corticosterone; Disease Models, Animal; Female; Male; Methionine; Mice, Inbred C57BL; Prepulse Inhibition; Psychotic Disorders; Reflex, Startle; Schizophrenia; Sensory Gating; Steroids; Stress, Psychological; Valine

Topics: Animals; Body Weight; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Fibronectins; Gene Expression Regulation; Genotype; Hippocampus; Humans; Male; Mental Disorders; Methionine; Mice; Mice, Transgenic; Neurogenesis; Neuronal Plasticity; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Physical Conditioning, Animal; Polymorphism, Single Nucleotide; Swimming; Valine

Topics: Analysis of Variance; Animals; Benzophenones; Brain; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Choice Behavior; Cognition Disorders; Disease Models, Animal; Exploratory Behavior; Genotype; Maze Learning; Methionine; Mice; Mice, Transgenic; Nitrophenols; Polymorphism, Single Nucleotide; Reaction Time; Tolcapone; Valine

Topics: Animals; Dentate Gyrus; Disease Models, Animal; Estrous Cycle; Female; Fragile X Mental Retardation Protein; Fragile X Syndrome; Genotype; Glycine; Hindlimb Suspension; Male; Memory; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuronal Plasticity; Receptors, N-Methyl-D-Aspartate; Spatial Behavior; Swimming; Valine

Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; Animals; Animals, Newborn; Disease Models, Animal; Epilepsy, Absence; Excitatory Amino Acid Antagonists; GABA Agents; Geniculate Bodies; Inhibitory Postsynaptic Potentials; Male; Nerve Net; Neural Inhibition; Neuropeptide Y; Rats; Rats, Mutant Strains; Rats, Wistar; Sodium Channel Blockers; Tetrodotoxin; Valine

Topics: Acetylcholine; Action Potentials; Animals; Disease Models, Animal; Excitatory Amino Acid Antagonists; GABA Antagonists; Gene Expression Regulation; Hyperalgesia; Male; Pain Threshold; Picrotoxin; Prefrontal Cortex; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Sciatica; Subcellular Fractions; Synaptic Transmission; Valine

Topics: Administration, Oral; Analgesics, Opioid; Animals; CHO Cells; Cricetinae; Cricetulus; Disease Models, Animal; Fentanyl; Humans; Hyperalgesia; Male; Mesocricetus; Mice; Mice, Inbred C57BL; Narcotic Antagonists; Oligopeptides; Peptides; Piperidines; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Neuropeptide; Valine

Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Disease Models, Animal; Excitatory Amino Acid Antagonists; Heart Rate; Hypoxia; Long-Term Potentiation; Male; Motor Neurons; Neural Pathways; Pulmonary Ventilation; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Respiratory Mechanics; Respiratory Muscles; Tidal Volume; Time Factors; Valine; Wakefulness

Topics: Animals; Antihypertensive Agents; Bone Marrow Transplantation; Brain Infarction; Brain Ischemia; Cells, Cultured; Chemokine CCL2; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Reperfusion Injury; Stromal Cells; Survival Rate; Tetrazoles; Treatment Outcome; Tumor Necrosis Factor-alpha; Valine; Valsartan

Topics: Animals; Antihypertensive Agents; Apoptosis; Apoptosis Regulatory Proteins; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Drug Therapy, Combination; Immunosuppressive Agents; Kidney; Male; Mycophenolic Acid; NF-kappa B; Random Allocation; Rats; Rats, Wistar; Tetrazoles; TNF-Related Apoptosis-Inducing Ligand; Treatment Outcome; Valine; Valsartan

Topics: Animals; Antihypertensive Agents; Atherosclerosis; Blood Pressure; Coronary Artery Disease; Disease Models, Animal; Endothelium, Vascular; Inflammation; Lipids; Male; Rabbits; Risk; Simvastatin; Stress, Mechanical; Tetrazoles; Valine; Valsartan

Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Chlorhexidine; Disease Models, Animal; Enalapril; Female; Peritoneal Dialysis; Peritoneum; Rats; Rats, Wistar; Sclerosis; Tetrazoles; Valine; Valsartan

Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Blood Pressure; Disease Models, Animal; Disease Progression; Gene Expression Regulation; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neutrophil Infiltration; NF-kappa B; Pancreatic Elastase; Rats; Rats, Wistar; Tetrazoles; Ultrasonography; Valine; Valsartan

Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Collagen; Disease Models, Animal; Female; Heart Rate; Hypertrophy, Left Ventricular; Ligation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Infarction; Myocytes, Cardiac; Ramipril; Receptor, Bradykinin B1; Tetrazoles; Valine; Valsartan; Ventricular Dysfunction, Left

Topics: Animals; Calcium; Calcium Channels; Cardiomyopathies; Disease Models, Animal; Hyperthyroidism; Imidazolidines; Myocardium; Rabbits; Renin-Angiotensin System; RNA, Messenger; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Tetrazoles; Thyroxine; Valine; Valsartan

Topics: Analysis of Variance; Animals; Animals, Genetically Modified; Animals, Newborn; Bicuculline; Cerebral Cortex; Disease Models, Animal; Doublecortin Domain Proteins; Doublecortin Protein; Electroporation; Excitatory Amino Acid Antagonists; Female; GABA Antagonists; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Glutamic Acid; Green Fluorescent Proteins; Humans; In Vitro Techniques; Malformations of Cortical Development; Membrane Potentials; Microtubule-Associated Proteins; Mutation; Nerve Net; Neurons; Neuropeptides; Pregnancy; Quinoxalines; Rats; Rats, Wistar; RNA, Small Interfering; Sodium Channel Blockers; Tetrodotoxin; Valine

Topics: Age of Onset; Albuminuria; Amino Acid Substitution; Animals; Case-Control Studies; Creatinine; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Disease Models, Animal; Genetic Variation; Gerbillinae; Humans; Hyperinsulinism; Ireland; Leucine; Metalloproteases; Mitochondrial Proteins; Polymorphism, Single Nucleotide; Reference Values; Valine

Topics: ADAM Proteins; ADAM10 Protein; Age Factors; Alanine; Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Behavior, Animal; Disease Models, Animal; Glutamic Acid; Humans; Isoleucine; Maze Learning; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Reaction Time; Swimming; Valine

Topics: Analysis of Variance; Animals; Axotomy; Calcitonin Gene-Related Peptide; CD3 Complex; Disease Models, Animal; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Facial Nerve Injuries; Galanin; GTP-Binding Proteins; Histidine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Nerve Regeneration; Neurons; Proto-Oncogene Proteins c-akt; ras Proteins; Recovery of Function; Time Factors; Valine

Topics: Age Factors; Alzheimer Disease; Animals; Brain Mapping; Disease Models, Animal; Glycine; Hippocampus; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neural Pathways; Proline; Septum of Brain; Serine; Stilbamidines; tau Proteins; Valine

Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Autoradiography; Cognition Disorders; Disease Models, Animal; Electric Stimulation; Electroencephalography; Epilepsy, Absence; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Long-Term Potentiation; Maze Learning; Mice; Mice, Transgenic; Neurons; Organophosphorus Compounds; Patch-Clamp Techniques; Phenotype; Protein Binding; Receptors, GABA-B; Tritium; Valine

Topics: Animals; Cell Movement; Cytokines; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Myeloid Differentiation Factor 88; Myocardial Reperfusion Injury; Myocardium; Neutrophils; NF-kappa B; Pyrrolidines; Receptors, Interleukin-1; Signal Transduction; Valine; Ventricular Dysfunction, Left

Topics: Animals; Disease Models, Animal; Glutathione; Malondialdehyde; Neuroprotective Agents; Oxidative Stress; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spinal Cord Injuries; Superoxide Dismutase; Valine

Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Models, Animal; Hypertension; Linear Models; Male; Proteinuria; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles; Valine; Valsartan

Topics: Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Animals; Autoimmune Diseases; Cytokines; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Male; Myocarditis; Rats; Rats, Inbred Lew; Tetrazoles; Th1 Cells; Th2 Cells; Valine; Valsartan

Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Disease Models, Animal; Female; Heart Failure; Male; Myocardium; Rabbits; Tetrazoles; Valine; Valsartan

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Angiotensin II Type 1 Receptor Blockers; Animals; Carotid Artery Diseases; Cerebrovascular Circulation; Disease Models, Animal; Male; Protein Kinase Inhibitors; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; rho-Associated Kinases; rhoA GTP-Binding Protein; Serotonin; Silicones; Tetrazoles; Valine; Valsartan; Vasoconstriction

Topics: Agouti-Related Protein; Animals; Anorexia; Appetite; Appetite Regulation; Dietary Proteins; Disease Models, Animal; Ependyma; Exploratory Behavior; Feeding Behavior; Food, Formulated; Ghrelin; Hypothalamus; Male; Neuropeptide Y; Rats; Rats, Wistar; Third Ventricle; Valine

Topics: Angiotensin II; Animals; Animals, Genetically Modified; Biomarkers; Cardiomegaly; Disease Models, Animal; Fatty Acids; Female; Humans; Hypoxanthine; Linoleic Acids; Male; Metabolomics; Mitochondria, Heart; Oxidative Stress; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Sirtuin 1; Survival Rate; Tetrazoles; Valine; Valsartan

Topics: Adipocytes; Adipose Tissue; Angiotensin II Type 1 Receptor Blockers; Animal Feed; Animals; Body Weight; Cytokines; Diabetes Mellitus, Type 2; Dietary Fats; Disease Models, Animal; Gene Expression; Glucose Intolerance; Inflammation; Insulin; Insulin Resistance; Insulin Secretion; Islets of Langerhans; Macrophages; Male; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Mitochondria; Tetrazoles; Valine; Valsartan

Topics: Animals; Biophysics; Chi-Square Distribution; Corpus Striatum; Disease Models, Animal; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Huntington Disease; In Vitro Techniques; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Mice; Mice, Inbred C57BL; Neuronal Plasticity; Recovery of Function; Synapses; Tissue Transplantation; Valine

Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Atherosclerosis; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelin-1; Endothelium, Vascular; Lipids; Male; Nitric Oxide; Pulmonary Artery; Rabbits; Tetrazoles; Treatment Outcome; Valine; Valsartan; Vasodilation

Topics: Angiogenesis Inhibitors; Animals; Carrageenan; Cell Proliferation; Disease Models, Animal; Drug Therapy, Combination; Endothelium, Vascular; Epoxy Compounds; Fibroblast Growth Factor 2; Hindlimb; Injections, Intra-Articular; Joints; Macrophages; Male; Neovascularization, Pathologic; Rats; Rats, Wistar; Synovial Membrane; Synovitis; Valine

Topics: Animals; Animals, Newborn; Cell Survival; Chymosin; Disease Models, Animal; Enzyme Precursors; Neovascularization, Physiologic; Neuroglia; Neurons; Oligopeptides; Probability; Prorenin Receptor; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Reference Values; Retina; Retinal Diseases; Retinal Vessels; RNA, Messenger; Tetrazoles; Valine; Valsartan

Topics: Animals; Animals, Newborn; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Dystonia; Entopeduncular Nucleus; Excitatory Amino Acid Antagonists; GABA Agents; Microinjections; Muscimol; Nipecotic Acids; Oximes; Pentylenetetrazole; Quinoxalines; Reaction Time; Severity of Illness Index; Time Factors; Valine

Topics: Angiopoietin-Like Protein 4; Angiopoietins; Angiotensin II Type 1 Receptor Blockers; Animals; Cerebral Cortex; Diabetes Mellitus; Disease Models, Animal; Gene Expression Regulation; Hypothalamus; Intra-Abdominal Fat; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Pituitary Gland; Resistin; RNA, Messenger; Subcutaneous Fat; Tetrazoles; Time Factors; Valine; Valsartan

Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Bicuculline; Disease Models, Animal; Estradiol; Estrogen Antagonists; Estrogens; Formaldehyde; Fulvestrant; Inflammation; Locus Coeruleus; Male; Microinjections; Pain; Rats; Rats, Sprague-Dawley; Valine

Topics: Adrenergic Agents; Animals; Corpus Striatum; Disease Models, Animal; Excitatory Amino Acid Antagonists; Functional Laterality; In Vitro Techniques; Male; Membrane Potentials; Neurons; Oxidopamine; Parkinson Disease; Patch-Clamp Techniques; Presenilin-1; Pyrrolidines; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Tyrosine 3-Monooxygenase; Up-Regulation; Valine

Topics: Animals; Chronic Disease; Cohort Studies; Comprehension; Computational Biology; Cross-Cultural Comparison; Disease Models, Animal; Female; Ganglia, Spinal; Gene Expression Profiling; Gene Expression Regulation; Genome-Wide Association Study; Genotype; Humans; Kv1.1 Potassium Channel; Linkage Disequilibrium; Male; Neurofilament Proteins; Neuropeptides; Oligonucleotide Array Sequence Analysis; Pain; Polymorphism, Genetic; Rats; Valine

Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Collagen; Desoxycorticosterone; Dinoprost; Disease Models, Animal; Heart Rate; Hypertension; Male; Membrane Glycoproteins; Mice; Mice, Transgenic; Myocardium; Myocytes, Cardiac; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tetrazoles; Transforming Growth Factor beta1; Valine; Valsartan

Topics: Albuminuria; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Biomarkers; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Dihydropyridines; Disease Models, Animal; Drug Therapy, Combination; Glomerulonephritis; Hypertension; Kidney; Kidney Diseases; Male; Organ Size; Rats; Rats, Inbred Dahl; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Tetrazoles; Time Factors; Valine; Valsartan

Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Arteries; Blood Vessels; Disease Models, Animal; Hydralazine; Hypertension; Mice; Mice, Inbred C57BL; NADPH Oxidases; Neointima; Oxidative Stress; Renin; Tetrazoles; Valine; Valsartan

Topics: Acid Sensing Ion Channels; Acidosis; Amino Acid Transport System y+; Animals; Biophysics; Brain Injuries; Calcium; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Electric Stimulation; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Extracellular Fluid; GABA Antagonists; Glucose; Hippocampus; Hydrogen-Ion Concentration; Hypoxia; Infarction, Middle Cerebral Artery; L-Lactate Dehydrogenase; Membrane Potentials; Mice; Mice, Knockout; Mutation; Nerve Tissue Proteins; Neurons; Oligonucleotides; Patch-Clamp Techniques; Picrotoxin; Putrescine; Sodium Channels; Spermine; Tetrazolium Salts; Time Factors; Transfection; Valine

Topics: Angiotensin II Type 2 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blood Pressure; Body Weight; Dietary Fats; Disease Models, Animal; Hypertension; Kidney Diseases; Male; Metabolic Syndrome; PPAR gamma; Rats; Rats, Inbred SHR; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan

Topics: Animals; Biomimetics; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Interleukin-1beta; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase Kinases; Myeloid Differentiation Factor 88; Myocytes, Cardiac; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Interleukin-1; Signal Transduction; Toll-Like Receptors; Valine

Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Brain Ischemia; Calcium; Cerebral Infarction; Cerebrosides; Charybdotoxin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Glucose; Glutamic Acid; Hippocampus; Hypoxia; In Vitro Techniques; Infarction, Middle Cerebral Artery; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; N-Methylaspartate; Neuroprotective Agents; Neurotoxins; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tetrazolium Salts; Valine

Topics: Administration, Oral; Alanine; Animals; Antiviral Agents; Cells, Cultured; Cidofovir; Cytomegalovirus; Cytosine; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Molecular Structure; Organophosphonates; Peptides; Prodrugs; Rats; Serine; Valine

Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Disease Models, Animal; Hypertension; Male; Medulla Oblongata; Microinjections; Peptide Fragments; Peptides; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sympathetic Nervous System; Tetrazoles; Valine; Valsartan

Topics: Administration, Cutaneous; Animals; Antihypertensive Agents; Disease Models, Animal; Drug Delivery Systems; Humans; Hypertension; Liposomes; Nanospheres; Particle Size; Rats; Rats, Wistar; Tetrazoles; Valine; Valsartan

Topics: Animals; Apoptosis; bcl-Associated Death Protein; bcl-X Protein; Calpain; Cardiomyopathy, Alcoholic; Carnitine; Disease Models, Animal; Dogs; Myocytes, Cardiac; Tetrazoles; Valine; Valsartan

Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Biophysics; Disease Models, Animal; Electric Stimulation; Electrodes; Excitatory Postsynaptic Potentials; Hippocampus; Humans; In Vitro Techniques; Isoleucine; Long-Term Potentiation; Mice; Mice, Transgenic; Mutation; Synapses; tau Proteins; Time Factors; Valine

Topics: Alzheimer Disease; Analysis of Variance; Animals; Cells, Cultured; Cerebral Cortex; Chromatography, High Pressure Liquid; Clorgyline; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Hydroxyindoleacetic Acid; Inositol 1,4,5-Trisphosphate Receptors; Methionine; Mice; Mice, Transgenic; Mitochondria; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Mutation; Neuroblastoma; Neurons; Neurotransmitter Agents; Organic Chemicals; Presenilin-1; Serotonin; Subcellular Fractions; Swimming; Transfection; Valine; Voltage-Dependent Anion Channels

Topics: Amino Acid Substitution; Animals; Animals, Genetically Modified; Aspartic Acid; Cell Survival; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Drosophila melanogaster; Drosophila Proteins; Female; Humans; Male; Parkinsonian Disorders; Suppression, Genetic; Ubiquitin-Protein Ligases; Valine

Topics: Amino Acid Substitution; Animals; Disease Models, Animal; Gene Knock-In Techniques; Genes, Lethal; HEK293 Cells; Humans; Janus Kinase 2; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation, Missense; Phenylalanine; Polycythemia Vera; STAT5 Transcription Factor; Valine

Topics: Animals; Animals, Genetically Modified; Autophagy; Caenorhabditis elegans; Disease Models, Animal; Gene Expression Regulation; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Methionine; Mutation; Parkinson Disease; Protein Serine-Threonine Kinases; Sirolimus; tau Proteins; Valine

Topics: Amides; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Circadian Rhythm; Disease Models, Animal; Drug Therapy, Combination; Fumarates; Heart Rate; Male; Motor Activity; Random Allocation; Rats; Rats, Inbred Lew; Rats, Transgenic; Receptors, Angiotensin; Renin; Tetrazoles; Valine; Valsartan

Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Cytochrome P-450 CYP11B2; Disease Models, Animal; Drug Therapy, Combination; Fadrozole; Follow-Up Studies; Microglia; Oxygen; Rats; Rats, Sprague-Dawley; Retinal Ganglion Cells; Retinal Neovascularization; Tetrazoles; Treatment Outcome; Valine; Valsartan

Topics: Amides; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Cardiomyopathy, Dilated; Cricetinae; Disease Models, Animal; Disease Progression; Drug Therapy, Combination; Fumarates; Male; Renin; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan; Ventricular Dysfunction, Left

Topics: Acetylcholine; Analysis of Variance; Animals; Atropine; Cholinesterase Inhibitors; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Hippocampus; In Vitro Techniques; Male; Muscarinic Antagonists; N-Methylaspartate; Neurons; Pentylenetetrazole; Physostigmine; Rats; Rats, Sprague-Dawley; Seizures; Sex Factors; Valine

Topics: Adrenocorticotropic Hormone; Analysis of Variance; Animals; Antidepressive Agents; Brain; Brain-Derived Neurotrophic Factor; Circadian Rhythm; Corticosterone; Corticotropin-Releasing Hormone; Dendritic Spines; Depression; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Exploratory Behavior; Food Preferences; Gene Expression Regulation; Male; Maze Learning; Methionine; Mice; Mice, Transgenic; Polymorphism, Single Nucleotide; Proto-Oncogene Proteins c-ets; Pyramidal Cells; RNA, Messenger; Serotonin Plasma Membrane Transport Proteins; Silver Staining; Stress, Psychological; Sucrose; Sweetening Agents; Swimming; Valine

Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apolipoproteins E; Atherosclerosis; Carotid Artery Diseases; Carotid Artery, Common; CD36 Antigens; Disease Models, Animal; Disease Progression; Focal Adhesion Kinase 1; Gene Deletion; JNK Mitogen-Activated Protein Kinases; Lipids; Lipoproteins, LDL; Macrophages; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Plaque, Atherosclerotic; Receptor, Angiotensin, Type 1; Rupture, Spontaneous; Superoxides; Tetrazoles; Time Factors; Valine; Valsartan

Topics: Alanine; Animals; Ataxia; Calcium; Calcium Signaling; Cold Temperature; Disease Models, Animal; Electromyography; Evoked Potentials; Ischemia; Kv1.1 Potassium Channel; Male; Mice; Mice, Transgenic; Microscopy, Confocal; Microscopy, Electron, Transmission; Muscle Fatigue; Muscle Tonus; Mutation; Myokymia; Neuromuscular Junction; Sciatic Nerve; Time Factors; Valine

Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Antibodies; Disease Models, Animal; Excitatory Amino Acid Antagonists; Green Fluorescent Proteins; Humans; Hyperalgesia; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Injections, Spinal; Male; Mice; Mice, Transgenic; Motor Activity; Neuralgia; Oligodeoxyribonucleotides, Antisense; Pain Measurement; Pain Threshold; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Spinal Cord; Spinal Nerves; Tetrodotoxin; Thrombospondins; Up-Regulation; Valine

Topics: Action Potentials; Animals; Biophysical Phenomena; Calcium Channels; Disease Models, Animal; Electric Stimulation; Epilepsy, Absence; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; Gene Expression Regulation; Glutamates; In Vitro Techniques; Indoles; Male; Mice; Mice, Mutant Strains; Nerve Net; Neurons; Patch-Clamp Techniques; Quinoxalines; Receptors, N-Methyl-D-Aspartate; Statistics, Nonparametric; Synapses; Thalamic Nuclei; Time Factors; Valine; Vesicular Glutamate Transport Protein 1

Topics: Anesthetics, Local; Animals; Bacterial Proteins; Carrier Proteins; Channelrhodopsins; Disease Models, Animal; Electroencephalography; Evoked Potentials; Excitatory Amino Acid Antagonists; Forelimb; Hyperalgesia; In Vitro Techniques; Ischemia; Luminescent Proteins; Membrane Potentials; Mice; Mice, Transgenic; Neurons; Optogenetics; Physical Stimulation; Quinoxalines; Reperfusion Injury; Tetrodotoxin; Valine

Topics: Age Factors; Age of Onset; Analysis of Variance; Animals; Animals, Newborn; Biophysics; Diabetes Mellitus, Experimental; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Gene Expression Regulation; Hippocampus; In Vitro Techniques; Neural Pathways; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Picrotoxin; Rats; Rats, Wistar; Reaction Time; Receptors, Glutamate; Streptozocin; Synapses; Valine

Topics: Animals; Biomarkers; Ceramides; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Disease Progression; Fructose; Insulin Resistance; Macaca mulatta; Male; Metabolic Syndrome; Obesity; Risk Factors; Serine C-Palmitoyltransferase; Sphingolipids; Valine

Topics: Aggression; Animals; Anxiety; Bioluminescence Resonance Energy Transfer Techniques; Brain; Defense Mechanisms; Disease Models, Animal; Gene Expression Regulation; Glycine; HEK293 Cells; Humans; Hydroxyindoleacetic Acid; Interpersonal Relations; Mice; Mice, Inbred C57BL; Mutation; Phenylalanine; Protein Binding; Protein Isoforms; Receptor, Serotonin, 5-HT2C; RNA Editing; RNA Precursors; RNA Splicing; RNA, Messenger; Transfection; Ultrasonics; Valine

Topics: Animals; Blotting, Western; Cardiomegaly; Cardiotonic Agents; Cell Line; Cytokines; Disease Models, Animal; Down-Regulation; Heart Failure; Isoproterenol; Male; Myocytes, Cardiac; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; RNA, Messenger; Spironolactone; Tetrazoles; Valine; Valsartan

Topics: Adolescent; Adult; Afghan Campaign 2001-; Animals; Brain-Derived Neurotrophic Factor; Disease Models, Animal; Female; Gene Expression Regulation; Genotype; Humans; Iraq War, 2003-2011; Male; Methionine; Middle Aged; Military Personnel; Polymorphism, Single Nucleotide; Psychiatric Status Rating Scales; Rats; Reflex, Startle; Stress Disorders, Post-Traumatic; Valine; Young Adult

Topics: Acyclovir; Administration, Oral; Administration, Topical; Animals; Disease Models, Animal; DNA Helicases; DNA Primase; DNA, Viral; Herpesvirus 1, Human; Keratitis, Herpetic; Mice; Mice, Inbred BALB C; Oxadiazoles; Real-Time Polymerase Chain Reaction; Tears; Treatment Outcome; Valacyclovir; Valine; Viral Proteins

Topics: Animals; Arterial Occlusive Diseases; Autoradiography; Blood Glucose; Brain Ischemia; Carbon Radioisotopes; Carotid Arteries; Cell Death; Disease Models, Animal; Female; Gerbillinae; Hippocampus; Male; Membrane Potentials; Neurons; Protein Biosynthesis; Valine

Topics: Acyclovir; Animals; Antiviral Agents; Disease Models, Animal; Female; Genes, Reporter; Herpes Simplex; Herpesvirus 1, Human; Keratitis, Herpetic; Luciferases; Luminescent Measurements; Mice; Organ Specificity; Time Factors; Valacyclovir; Valine

Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Aortic Valve Stenosis; Cardiac Catheterization; Cytoplasm; Disease Models, Animal; Endothelin-1; Gene Expression Regulation; Heart; Insulin-Like Growth Factor I; Microscopy, Confocal; Myocardium; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Renin-Angiotensin System; RNA, Messenger; Stress, Mechanical; Swine; Systole; Tetrazoles; Valine; Valsartan

Topics: Albuminuria; Amlodipine; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Drug Therapy, Combination; Hypertension; Kidney Glomerulus; Male; Membrane Proteins; Proteins; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Sclerosis; Systole; Tetrazoles; Valine; Valsartan; Verapamil

Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Glucose; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Gene Expression; Glucose Tolerance Test; Glucose Transporter Type 4; Hyperglycemia; Liver; Male; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Nicorandil; Nifedipine; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Rats, Wistar; RNA, Messenger; Saralasin; Tetrazoles; Valine; Valsartan

Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Action Potentials; Alanine; Animals; Avoidance Learning; Calcium; Cell Membrane; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Electric Stimulation; Genotype; Glycine; Gyrus Cinguli; Humans; In Vitro Techniques; Long-Term Potentiation; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Mice, Transgenic; Motor Activity; Mutation; Neural Pathways; Neuronal Plasticity; Neurons; Patch-Clamp Techniques; Quinpirole; Superoxide Dismutase; Valine

Topics: Acyclovir; Animals; Antiviral Agents; Aqueous Humor; Biological Availability; Chlorocebus aethiops; Cornea; Corneal Stroma; Disease Models, Animal; Drug Evaluation, Preclinical; Epithelium, Corneal; Herpesvirus 1, Human; Keratitis, Herpetic; Prodrugs; Rabbits; Trifluridine; Valacyclovir; Valine

Topics: Animals; Behavior, Animal; Depression; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Male; Microdialysis; Microinjections; Motor Activity; Nucleus Accumbens; Physical Stimulation; Rats; Rats, Sprague-Dawley; Swimming; Tail; Time Factors; Valine

Topics: Acute Disease; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Exploratory Behavior; Injections, Spinal; Male; Pancreatitis; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Valine

Topics: Aldosterone; Angiotensin II; Animals; Cardiomegaly; Collagen Type I; Disease Models, Animal; Drug Therapy, Combination; Fibrosis; Heart; In Situ Hybridization; Infusions, Parenteral; Male; Myocardium; Nephrectomy; NF-kappa B; Rats; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Tetrazoles; Valine; Valsartan

Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Dogs; Myocardial Infarction; Myocardial Reperfusion; Myocardium; Random Allocation; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Treatment Outcome; Up-Regulation; Valine; Valsartan; Ventricular Function, Left

Topics: Angioplasty, Balloon; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzazepines; Blood Pressure; Carotid Artery Injuries; Disease Models, Animal; Hypertension; Nitric Oxide; Oxidative Stress; Rats; Rats, Sprague-Dawley; Tetrazoles; Tunica Intima; Valine; Valsartan

Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Blood Glucose; Crosses, Genetic; Deoxyglucose; Diabetes Mellitus, Type 2; Disease Models, Animal; Energy Intake; Gene Expression Regulation; Glucose Transporter Type 4; Imidazoles; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mice, Obese; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Phosphoproteins; Phosphorylation; Protein Processing, Post-Translational; Protein Transport; Pyridines; Signal Transduction; Superoxides; Tetrazoles; Tumor Necrosis Factor-alpha; Valine; Valsartan

Topics: Age Factors; Alleles; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Behavior, Animal; Blotting, Southern; Brain Chemistry; Choice Behavior; Disease Models, Animal; Female; Genotype; Humans; Immunohistochemistry; Isoleucine; Male; Maze Learning; Mice; Mice, Transgenic; Molecular Sequence Data; Motor Activity; Mutation; Neurofibrillary Tangles; Peptide Fragments; Reaction Time; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sex Factors; Survival Rate; tau Proteins; Valine

Topics: Animals; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Escherichia coli; Glucose; Infusions, Intravenous; Injections, Intravenous; Interleukin-6; Japan; Lactic Acid; Lipopolysaccharides; Macrophages, Peritoneal; Male; Mice; Mice, Inbred ICR; Riboflavin; Shock, Septic; Time Factors; Valine

Topics: Animals; Anti-HIV Agents; CCR5 Receptor Antagonists; Disease Models, Animal; Drug Evaluation, Preclinical; HIV Infections; HIV-1; Macaca mulatta; Pyrazoles; Reassortant Viruses; Simian Acquired Immunodeficiency Syndrome; Simian Immunodeficiency Virus; Valine; Viral Load; Virus Replication

Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Apolipoproteins E; Arteriosclerosis; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Fatty Acids, Monounsaturated; Fluvastatin; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Male; Mice; Mice, Knockout; Oxidative Stress; Tetrazoles; Valine; Valsartan

Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Blotting, Western; Densitometry; Disease Models, Animal; Dogs; Electrocardiography; Electrophoresis, Gel, Two-Dimensional; Heart Rate; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Myocardial Infarction; Myocardial Reperfusion; Random Allocation; Tetrazoles; Tissue Inhibitor of Metalloproteinase-3; Treatment Outcome; Valine; Valsartan; Ventricular Dysfunction, Left

Topics: Administration, Oral; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cyclic N-Oxides; Disease Models, Animal; Glucose; Hypertension; Insulin; Insulin Resistance; Male; Muscle, Skeletal; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Spin Labels; Tetrazoles; Valine; Valsartan

Topics: Animals; Animals, Newborn; Arginine; Blotting, Western; Brain; Cells, Cultured; Cerebellum; Cricetinae; Cricetulus; Detergents; Disease Models, Animal; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique; Gene Expression; Glial Fibrillary Acidic Protein; Golgi Apparatus; Golgi Matrix Proteins; Immunoprecipitation; Leucine; Membrane Proteins; Methionine; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neurodegenerative Diseases; Neurons; Octoxynol; Prion Diseases; Protein Structure, Tertiary; PrPSc Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfur Isotopes; Time Factors; Type C Phospholipases; Valine

Topics: Acyclovir; Administration, Oral; Animals; Antibodies, Monoclonal; Antibodies, Viral; Antiviral Agents; Disease Models, Animal; Drug Therapy, Combination; Female; Herpes Genitalis; Herpesvirus 2, Human; Injections, Intraperitoneal; Mice; Mice, Inbred BALB C; Secondary Prevention; Valacyclovir; Valine; Viral Envelope Proteins; Virus Latency

Topics: Animals; Antioxidants; Brain; Catalase; Cerebral Cortex; Chromans; Disease Models, Animal; Enzyme Inhibitors; Fluoresceins; Free Radicals; Glutathione; Glutathione Peroxidase; Humans; Isoleucine; Leucine; Male; Maple Syrup Urine Disease; Mitochondria; Neurons; NG-Nitroarginine Methyl Ester; Oxidative Stress; Oxygen; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Valine

Topics: 8-Hydroxy-2'-Deoxyguanosine; Administration, Oral; Aldehydes; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensins; Animals; Body Weight; Deoxyguanosine; Diabetes Mellitus, Type 2; Disease Models, Animal; Insulin; Islets of Langerhans; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Phosphoproteins; Rats; Rats, Inbred OLETF; Rats, Long-Evans; Tetrazoles; Time Factors; Valine; Valsartan

Topics: Analysis of Variance; Animals; Capsaicin; Disease Models, Animal; Dizocilpine Maleate; Electromyography; Excitatory Amino Acid Antagonists; Facial Pain; Inflammation; Jaw; Male; Muscle, Skeletal; Nociceptors; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex; Temporomandibular Joint; Valine

Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Abdominal; Arteriosclerosis; Captopril; Cholesterol, Dietary; Disease Models, Animal; Endothelium, Vascular; Male; Rabbits; Tetrazoles; Ultrasonography; Valine; Valsartan

Topics: Adaptation, Physiological; Animals; Disease Models, Animal; Male; Methylmalonic Acid; Rats; Rats, Inbred Lew; Regeneration; Short Bowel Syndrome; Valine

Topics: Animals; Aristolochic Acids; Bosentan; Collagen Type I; Connective Tissue Growth Factor; Disease Models, Animal; Fibrosis; Kidney; Kidney Diseases; Male; Plasminogen Activator Inhibitor 1; Rats; Rats, Sprague-Dawley; Sulfonamides; Tetrazoles; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta1; Valine; Valsartan

Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Basilar Artery; Blood Pressure; Disease Models, Animal; Drug Therapy, Combination; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Hypertrophy, Left Ventricular; Mesenteric Arteries; Pioglitazone; Rats; Rats, Inbred SHR; Rats, Wistar; Rosiglitazone; Simvastatin; Tetrazoles; Thiazolidinediones; Tunica Media; Valine; Valsartan

Topics: Animals; Bradykinin; Bradykinin B2 Receptor Antagonists; Cardiotonic Agents; Creatine Kinase, MB Form; Disease Models, Animal; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Random Allocation; Rats; Rats, Sprague-Dawley; Receptor, Bradykinin B2; Tetrazoles; Valine; Valsartan; Ventricular Function, Left

Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Afferent Pathways; Age Factors; Animals; Calcium Channel Blockers; Calcium Channels, N-Type; Disease Models, Animal; Electric Stimulation; Electroencephalography; Epilepsy, Absence; Evoked Potentials; Excitatory Postsynaptic Potentials; Homeostasis; Lidocaine; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; omega-Agatoxin IVA; omega-Conotoxin GVIA; Patch-Clamp Techniques; Picrotoxin; Pyramidal Cells; Somatosensory Cortex; Synaptic Transmission; Thalamic Nuclei; Valine

Topics: Acute Disease; Amino Acyl-tRNA Synthetases; Animals; Arginine; Disease Models, Animal; Liver; Male; Myocardial Ischemia; Protein Biosynthesis; Rabbits; RNA, Transfer; Seasons; Time Factors; Valine

Topics: Adenosine Triphosphate; Angiotensin II Type 1 Receptor Blockers; Animals; Bile; Cell Line; Cell Membrane; Disease Models, Animal; Estrone; Hepatocytes; Humans; Hyperbilirubinemia; Liver-Specific Organic Anion Transporter 1; Male; Membrane Transport Proteins; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Rats; Rats, Sprague-Dawley; Sincalide; Solute Carrier Organic Anion Transporter Family Member 1B3; Tetrazoles; Transfection; Valine; Valsartan

Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Animals, Genetically Modified; Blood Pressure; Disease Models, Animal; Hypertension, Renal; Kidney Glomerulus; Male; Malondialdehyde; Mice; Microscopy, Electron, Transmission; NADPH Oxidases; Neprilysin; Oxidative Stress; Peptidyl-Dipeptidase A; Podocytes; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; RNA, Messenger; Tetrazoles; Valine; Valsartan

Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Inflammatory Agents; Benzimidazoles; Biphenyl Compounds; Carrageenan; Disease Models, Animal; Edema; Female; Gastric Mucosa; Indomethacin; Losartan; Rats; Rats, Wistar; Stomach Ulcer; Tetrazoles; Valine; Valsartan

Topics: Angiotensin II Type 2 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Dendritic Cells; Disease Models, Animal; Disease Progression; Fibrosis; Immunohistochemistry; Kidney Diseases; Kidney Function Tests; Kidney Tubules; Membrane Glycoproteins; Proteinuria; Rats; Rats, Sprague-Dawley; Tetrazoles; Valine; Valsartan

Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Cell Proliferation; Disease Models, Animal; Diuretics; Fibrosis; Glomerulonephritis, Membranoproliferative; Ki-67 Antigen; Kidney; Mineralocorticoid Receptor Antagonists; Rats; Rats, Sprague-Dawley; Spironolactone; Tetrazoles; Transforming Growth Factor beta; Valine; Valsartan

Topics: Acyclovir; Administration, Oral; Animals; Antiviral Agents; Cornea; Disease Models, Animal; DNA, Viral; Gene Dosage; Herpesvirus 1, Human; Humans; Keratitis, Dendritic; Keratitis, Herpetic; Male; Mice; Mice, Inbred BALB C; Middle Aged; Polymerase Chain Reaction; Prodrugs; Valacyclovir; Valine

Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Catheterization; Cyclic N-Oxides; Disease Models, Animal; Hydralazine; Male; Nitric Oxide; Oxidants; Oxidative Stress; Rabbits; Spin Labels; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents; Vasodilator Agents

Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Helium; High Pressure Neurological Syndrome; Hippocampus; In Vitro Techniques; Magnesium; Male; Pressure; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Valine

Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Fibrillation; Blotting, Western; Calpain; Cilazapril; Disease Models, Animal; Dogs; Female; Gene Expression; Gene Expression Regulation; Heart Atria; Male; Myocytes, Cardiac; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazoles; Ultrasonography; Valine; Valsartan

Topics: Acetophenones; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Calcitonin Gene-Related Peptide; Captopril; Cell Adhesion; Chymases; Disease Models, Animal; Endothelial Cells; Imidazoles; Intestines; Ischemia; Leukocyte Rolling; Leukocytes; Male; Mice; Mice, Inbred C57BL; Microscopy, Video; NADPH Oxidases; Pyridines; Pyrimidinones; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Calcitonin Gene-Related Peptide; Reperfusion Injury; Tetrazoles; Valine; Valsartan; Venules

Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Cardiomegaly; Disease Models, Animal; Fibrosis; Heart Ventricles; Hypertension, Renovascular; Ligation; Male; Malondialdehyde; Membrane Glycoproteins; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; Rats; Rats, Sprague-Dawley; Renal Artery; Superoxides; Tetrazoles; Valine; Valsartan; Ventricular Function, Left; Ventricular Remodeling

Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Carotid Arteries; Compliance; Disease Models, Animal; Hypertension; Male; Rats; Rats, Inbred SHR; Sodium Chloride, Dietary; Tetrazoles; Time Factors; Valine; Valsartan

Topics: Aminopeptidases; Animals; Arthritis, Rheumatoid; Bone Resorption; Cell Differentiation; Cells, Cultured; Disease Models, Animal; Enzyme Inhibitors; Epoxy Compounds; Female; Glycoproteins; Humans; Joints; Osteoclasts; Peptidoglycan; Polysaccharides; Rats; Rats, Inbred Lew; Severity of Illness Index; Valine

Topics: Animals; Basal Ganglia; Caudate Nucleus; Cricetinae; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Dystonia; Excitatory Amino Acid Antagonists; Microinjections; Movement; Muscle Contraction; Mutation; Posture; Putamen; Pyrrolidinones; Quinoxalines; Reaction Time; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Severity of Illness Index; Valine

Topics: Adipocytes; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blood Glucose; Calcium Channel Blockers; Cell Size; Diabetes Mellitus, Type 2; Disease Models, Animal; Insulin; Intra-Abdominal Fat; Male; Obesity; PPAR gamma; Random Allocation; Rats; Rats, Long-Evans; Telmisartan; Tetrazoles; Valine; Valsartan

Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Urea Nitrogen; Blotting, Western; Creatinine; Disease Models, Animal; DNA; Heart Failure; Immunohistochemistry; Kidney Failure, Chronic; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; Nephrectomy; Oxidative Stress; Receptor, Angiotensin, Type 1; Signal Transduction; Tetrazoles; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta1; Treatment Outcome; Up-Regulation; Valine; Valsartan; Ventricular Function, Left

Topics: Actins; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Biomarkers; Blotting, Western; Collagen Type I; Disease Models, Animal; Disease Progression; Fatty Liver; Hypoglycemic Agents; Immunohistochemistry; Male; Pioglitazone; PPAR gamma; Rats; Rats, Inbred F344; Spectrophotometry; Telmisartan; Tetrazoles; Thiazolidinediones; Treatment Outcome; Valine; Valsartan

Topics: Animals; Antihypertensive Agents; Cilazapril; Disease Models, Animal; Male; Matrix Metalloproteinase 2; Myocardial Infarction; Myocardium; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Tetrazoles; Tissue Inhibitor of Metalloproteinase-1; Valine; Valsartan

Topics: Acute Disease; Angiotensin II; Animals; Antihypertensive Agents; Cell Adhesion Molecules; Cell Communication; Cells, Cultured; Disease Models, Animal; Fibroblasts; Gene Expression Regulation; Male; Myocardial Infarction; Myocardium; Myocytes, Cardiac; Random Allocation; Rats; Rats, Inbred Lew; Rats, Wistar; Stress, Mechanical; Tetrazoles; Valine; Valsartan; Ventricular Remodeling

Topics: Animals; Animals, Genetically Modified; Apoptosis; Blood Pressure; Blotting, Western; C-Reactive Protein; Cells, Cultured; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Insulin Resistance; Male; Muscle, Smooth, Vascular; NADPH Oxidases; Probability; Random Allocation; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sensitivity and Specificity; Superoxide Dismutase; Tetrazoles; Valine; Valsartan; Vasculitis

Topics: Animals; Blotting, Western; Disease Models, Animal; Enzyme Inhibitors; Glucagon-Like Peptide 1; In Vitro Techniques; Incretins; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Phosphatidylinositol 3-Kinases; Protein Kinases; Pyrroles; Random Allocation; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Sirolimus; Time Factors; TOR Serine-Threonine Kinases; Valine

Topics: Animals; Antibody Formation; Autoimmunity; CCR5 Receptor Antagonists; Cyclosporine; Disease Models, Animal; Graft Survival; Heart Transplantation; HIV Infections; Humans; Immunosuppressive Agents; Inflammation; Isoantibodies; Kidney Transplantation; Macaca fascicularis; Macrophages; Male; Pyrazoles; Stress, Physiological; T-Lymphocytes; Transplantation Tolerance; Transplantation, Homologous; Valine; Vascular Diseases

Topics: Actins; Angiotensin II Type 1 Receptor Blockers; Animals; Atrial Fibrillation; Cell Communication; Cell Proliferation; Cells, Cultured; Collagen Type I; Culture Media; Disease Models, Animal; Dogs; Extracellular Matrix; Fibroblasts; Fibronectins; Heterocyclic Compounds, 4 or More Rings; Muscle Contraction; Myocytes, Cardiac; Tachycardia; Tetrazoles; Valine; Valsartan; Ventricular Remodeling

Topics: Acetophenones; Amlodipine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Apoptosis; Biopterins; Blood Pressure; Calcium Channel Blockers; Disease Models, Animal; Endothelium, Vascular; Heart Failure, Diastolic; Hydralazine; Hypertension; Male; MAP Kinase Kinase Kinase 5; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Nitric Oxide Synthase Type III; Rats; Rats, Inbred Dahl; Receptor, Angiotensin, Type 1; Signal Transduction; Sodium Chloride, Dietary; Superoxides; Tetrazoles; Time Factors; Valine; Valsartan; Vasodilation

Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Antihypertensive Agents; Behavior, Animal; Brain; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Humans; Memory; Mice; Mice, Transgenic; Protein Structure, Quaternary; Random Allocation; Space Perception; Tetrazoles; Valine; Valsartan

Topics: Angioplasty, Balloon; Animals; Disease Models, Animal; Endothelial Cells; Endothelium, Vascular; Hyperplasia; Male; Postoperative Period; Rabbits; Random Allocation; Tetrazoles; Tunica Intima; Valine; Valsartan; von Willebrand Factor

Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Colitis; Cytokines; Disease Models, Animal; Humans; Immunohistochemistry; Inflammatory Bowel Diseases; Male; Rats; Rats, Sprague-Dawley; Tetrazoles; Valine; Valsartan

Topics: Adipocytes, White; Adiponectin; Angiotensin II Type 1 Receptor Blockers; Animals; Apolipoproteins E; Atherosclerosis; Cell Differentiation; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Disease Models, Animal; Gene Deletion; Gene Expression; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Obesity; PPAR gamma; Receptor, Angiotensin, Type 1; Tetrazoles; Valine; Valsartan

Topics: Animals; Astrocytes; Brain Injuries; CD11b Antigen; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glial Fibrillary Acidic Protein; Gliosis; Hippocampus; Ion Channels; Kynurenic Acid; Male; Microglia; Quinoxalines; Rats; Rats, Wistar; Receptors, Glutamate; Sodium Channel Blockers; Time Factors; Treatment Outcome; Up-Regulation; Valine

Topics: ADAM Proteins; ADAM10 Protein; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Analysis of Variance; Animals; Cell Death; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Hippocampus; Indoles; Kainic Acid; Leucine; Membrane Proteins; Mice; Mice, Transgenic; Mutation; Neurons; Plant Lectins; Seizures; Stress, Physiological; Valine

Topics: Acetylcholine; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Carotid Arteries; Disease Models, Animal; Hypertension; Male; NADPH Oxidases; Peptidyl-Dipeptidase A; PPAR gamma; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin; Telmisartan; Tetrazoles; Valine; Valsartan; Vasodilation; Vasodilator Agents

Topics: Amino Acid Substitution; Animals; Bone Marrow Transplantation; Cell Line, Tumor; Colony-Forming Units Assay; Disease Models, Animal; Endpoint Determination; Flow Cytometry; Hematopoietic System; Humans; Janus Kinase 2; Mice; Mice, Inbred C57BL; Phenylalanine; Polycythemia Vera; Protein Kinase Inhibitors; Pyrrolidines; Signal Transduction; Sulfonamides; Survival Rate; Treatment Outcome; Valine

Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Brain Stem; Calcium Channel Blockers; Cerebral Cortex; Disease Models, Animal; Down-Regulation; Enalapril; Hypertension; Male; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Stroke; Tetrazoles; Time Factors; Valine; Valsartan

Topics: Animals; Cilazapril; Collagen; Disease Models, Animal; Male; Myocardial Infarction; Myocardium; Random Allocation; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Tetrazoles; Valine; Valsartan

Topics: Angiotensin II; Animals; Animals, Genetically Modified; Antihypertensive Agents; Antioxidants; Apoptosis; Blood Pressure; Cyclic N-Oxides; Disease Models, Animal; Fatty Liver; Lipid Peroxidation; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Renin; Renin-Angiotensin System; Spin Labels; Tetrazoles; Valine; Valsartan

Topics: Animals; Blood-Brain Barrier; Catecholamines; Disease Models, Animal; Dogs; Tyrosine; Valine; Ventricular Fibrillation

Topics: Animals; Antiviral Agents; CD4-Positive T-Lymphocytes; Disease Models, Animal; Genes, env; HIV; HIV Infections; HIV Protease Inhibitors; HIV-1; HLA-A Antigens; HLA-DR Antigens; HLA-DR Serological Subtypes; Humans; Macaca; Nevirapine; Pyridines; Reverse Transcriptase Inhibitors; Ritonavir; Simian Immunodeficiency Virus; Thiazoles; Time Factors; Valine; Virulence; Virus Latency; Virus Replication

Topics: Acetaminophen; Administration, Oral; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Ethanol; Lipid Peroxides; Liver; Liver Diseases; Male; Rats; Ursodeoxycholic Acid; Valine

Topics: 2-Aminopurine; Acute Disease; Acyclovir; Animals; Antiviral Agents; Brain Stem; Disease Models, Animal; Ear, External; Famciclovir; Female; Ganglia, Spinal; Herpes Simplex; Herpesvirus 1, Human; Mice; Mice, Inbred BALB C; Prodrugs; Trigeminal Ganglion; Valacyclovir; Valine; Virus Activation; Virus Latency; Virus Replication

Topics: Animals; Body Weight; Carcinoma, Ehrlich Tumor; Cerebral Cortex; Disease Models, Animal; Female; Glioma; Injections, Intra-Arterial; Mathematics; Neoplasm Transplantation; Proteins; Rats; Rats, Wistar; RNA, Transfer, Amino Acyl; Valine

Topics: Adenylyl Cyclases; Analysis of Variance; Animals; Bone Development; Bone Neoplasms; Disease Models, Animal; Female; Femur; Humans; Lactams; Molecular Weight; Osteoporosis, Postmenopausal; Osteosarcoma; Ovariectomy; Parathyroid Hormone; Peptide Fragments; Rats; Serine; Structure-Activity Relationship; Tumor Cells, Cultured; Valine

Topics: 2-Aminopurine; Acyclovir; Animals; Antiviral Agents; Bromodeoxyuridine; Cell Line; Disease Models, Animal; Famciclovir; Hepatitis, Animal; Herpes Zoster; Herpesvirus 1, Human; Liver; Mice; Mice, Inbred BALB C; Valacyclovir; Valine; Viral Plaque Assay; Virus Replication

Topics: Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzazepines; Blood Pressure; Cardiac Output; Cardiac Pacing, Artificial; Diastole; Disease Models, Animal; Endothelins; Epinephrine; Heart Failure; Heart Rate; Hemodynamics; Norepinephrine; Pulmonary Artery; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Swine; Tetrazoles; Valine; Valsartan; Ventricular Function, Left

Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzazepines; Blood Pressure; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Heart Rate; Hypertension; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Telemetry; Tetrazoles; Treatment Outcome; Valine; Valsartan

Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Cardiac Pacing, Artificial; Coronary Vessels; Disease Models, Animal; Exercise Test; Heart Failure; Hemodynamics; Male; Regional Blood Flow; Swine; Tetrazoles; Valine; Valsartan; Vascular Resistance; Ventricular Function, Left

Topics: Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, Thoracic; Arteriosclerosis; Benzazepines; Cholesterol, Dietary; Disease Models, Animal; Endothelium, Vascular; Immunohistochemistry; Male; Muscle, Smooth, Vascular; Rabbits; Reference Values; Tetrazoles; Valine; Valsartan

Topics: Animals; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Hyperalgesia; Injections, Spinal; Male; Motor Activity; Pain; Physical Stimulation; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Spinal Cord Injuries; Valine

Topics: 2-Aminopurine; Acyclovir; Animals; Antiviral Agents; Disease Models, Animal; Famciclovir; Herpes Simplex; Herpesvirus 1, Human; Mice; Recurrence; Valacyclovir; Valine; Virus Latency

Topics: Angiotensin I; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Cardiomegaly; Chronic Disease; Disease Models, Animal; Fever; Fourier Analysis; Heart Rate; Hypertension; Hyperthyroidism; Injections, Intraperitoneal; Male; Rats; Rats, Wistar; Renin; Renin-Angiotensin System; Signal Processing, Computer-Assisted; Tachycardia; Tetrazoles; Thyroid Hormones; Thyrotoxicosis; Thyroxine; Valine; Valsartan; Weight Loss

Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Blotting, Northern; Disease Models, Animal; Gene Expression; In Situ Hybridization; Kidney; Macrophages; Male; Nephrectomy; Nephritis, Interstitial; Osteopontin; Ramipril; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sialoglycoproteins; Tetrazoles; Valine; Valsartan

Topics: Action Potentials; Amygdala; Animals; Disease Models, Animal; Electric Stimulation; Epilepsy; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Kindling, Neurologic; Neural Pathways; Neurons; Phosphinic Acids; Propanolamines; Quinoxalines; Rats; Valine

Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzazepines; Blood Pressure; Catecholamines; Collagen; Diastole; Disease Models, Animal; Drug Therapy, Combination; Echocardiography; Endothelin-1; Gene Expression; Heart Failure; Heart Function Tests; Hydroxyproline; Myocardium; Myosin Heavy Chains; Organ Size; Rats; Rats, Inbred Dahl; Receptors, Angiotensin; RNA, Messenger; Sodium Chloride, Dietary; Survival Rate; Tetrazoles; Valine; Valsartan; Ventricular Remodeling

Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Calcium-Binding Proteins; Calpain; Disease Models, Animal; Gene Expression Regulation; Heart; Heart Rate; Imidazoles; Male; Myocardial Infarction; Protein Biosynthesis; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Tetrazoles; Transcription, Genetic; Valine; Valsartan

Topics: Acetylcholine; Angiotensin II; Angiotensinogen; Animals; Animals, Genetically Modified; Antihypertensive Agents; Dinoprost; Disease Models, Animal; Endothelium, Vascular; F2-Isoprostanes; Humans; Hypertension; Ketone Oxidoreductases; Male; Nitrates; Nitrites; Nitroprusside; Norepinephrine; Rats; Rats, Sprague-Dawley; Renal Artery; Renin; Superoxide Dismutase; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents; Vasodilation

Topics: Acidosis; Animals; Body Weight; Cholesterol; Creatinine; Disease Models, Animal; Eating; Isoleucine; Kidney Failure, Chronic; Leucine; Male; Muscle, Skeletal; Nephrectomy; Proteins; Rats; Rats, Wistar; Urea; Uremia; Valine

Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Basement Membrane; Blood Pressure; Diabetes Mellitus, Experimental; Disease Models, Animal; Disease Progression; Humans; Kidney; Kidney Glomerulus; Male; Organ Size; Ramipril; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan

Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Chemokine CCL2; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension, Malignant; Hypertension, Renovascular; Immunohistochemistry; Kidney; Macrophages; Male; Nephritis; Organ Size; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Survival Rate; Tetrazoles; Valine; Valsartan

Topics: Acetylcholine; Animals; Antihypertensive Agents; Arteriosclerosis; Biomarkers; Blood Pressure; Cholesterol; Cholesterol, Dietary; Disease Models, Animal; Dose-Response Relationship, Drug; Factor VIII; Fibrin Fibrinogen Degradation Products; Fibrinogen; Fibrinolysis; Hypercholesterolemia; Male; Myocardial Contraction; Rabbits; Tetrazoles; Time; Treatment Outcome; Valine; Valsartan

Topics: 2-Aminopurine; Acyclovir; Animals; Antiviral Agents; Apoptosis; Brain Stem; Disease Models, Animal; DNA Fragmentation; Famciclovir; Female; Ganciclovir; Guanine; Herpes Simplex; Herpesvirus 1, Human; Humans; In Situ Nick-End Labeling; Mice; Mice, Inbred BALB C; Valacyclovir; Valine

Topics: Animals; Brain; Disease Models, Animal; Fatty Acids; Histidine; Hydroxyindoleacetic Acid; Hypothalamus; Isoleucine; Leucine; Liver Cirrhosis; Phenylalanine; Portacaval Shunt, Surgical; Rats; Serotonin; Tryptophan; Tyrosine; Valine

Topics: Amniotic Fluid; Animals; Body Weight; Disease Models, Animal; Fasting; Female; Fetal Blood; Fetal Growth Retardation; Glycine; Liver; Male; Maternal-Fetal Exchange; Organ Size; Pregnancy; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Valine

Topics: Amino Acids; Animals; Aspartic Acid; Blood Flow Velocity; Blood Pressure; Brain Ischemia; Cerebrovascular Circulation; Chromatography, High Pressure Liquid; Disease Models, Animal; Glutamates; Glutamic Acid; Glutamine; Hematoma, Subdural; Male; Rats; Rats, Inbred Strains; Regression Analysis; Valine

Topics: 2-Amino-5-phosphonovalerate; Allopurinol; Amino Acids; Animals; Antioxidants; Baclofen; Corpus Striatum; Dibenzocycloheptenes; Disease Models, Animal; Dizocilpine Maleate; Huntington Disease; Ketamine; Male; Neuropeptide Y; Nimodipine; Peptides; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Substance P; Taurine; Valine

Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Aspartic Acid; Dibenzocycloheptenes; Disease Models, Animal; Dizocilpine Maleate; Electric Stimulation; Electrophysiology; Epilepsy; Evoked Potentials; Hippocampus; In Vitro Techniques; N-Methylaspartate; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Valine

Topics: Animals; Brain; Brain Neoplasms; Carbon Radioisotopes; Disease Models, Animal; Female; Glucose; Protein Biosynthesis; Proteins; Rats; Rats, Inbred Strains; Valine

Topics: Animals; Animals, Newborn; Autoradiography; Brain; Brain Ischemia; Disease Models, Animal; Hypoxia, Brain; Nerve Tissue Proteins; Rats; Rats, Inbred Strains; Valine

Topics: Ampicillin; Animals; Azo Compounds; Biopsy; Blood Cell Count; Body Weight; Disease Models, Animal; FIGLU Test; Folic Acid; Glutarates; Growth; Haplorhini; Hematocrit; Hepatectomy; Histidine; Liver; Male; Malonates; Papio; Propionates; Sodium; Valine; Vitamin B 12; Vitamin B 12 Deficiency