Compounds > valine

valine and Disease Exacerbation

valine has been researched along with Disease Exacerbation in 110 studies

Research

Studies (110)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (4.55)18.2507
2000's45 (40.91)29.6817
2010's55 (50.00)24.3611
2020's5 (4.55)2.80

Authors

AuthorsStudies
Jing, XJ; Ren, SJ; Therriault, J; Xiong, YL; Zhang, H1
Bai, M; Chen, J; Dai, H; Han, F; Lin, W; Wang, J; Weng, C; Xie, X; Zhu, H1
Berg, T; Boeker, KHW; Buggisch, P; C-Registry, GH; Günther, R; Hinrichsen, H; Klinker, H; Manns, MP; Mauss, S; Müller, T; Serfert, Y; Wiegand, J; Zeuzem, S1
El-Sisi, AE; Zakaria, S1
Anderson, MA; Birkinshaw, RW; Blombery, P; Chen, X; Conway, T; Czabotar, PE; Gong, JN; Huang, DCS; McBean, M; Nguyen, T; Roberts, AW; Seymour, JF; Thijssen, R; Thompson, ER; Westerman, DA1
Feng, N; Gu, S; Jiang, H; Liu, F; Lv, L; Yan, R; Zhang, N1
Amemiya, M; Hayashi, N; Koshima, Y; Kuriyama, S; Matsuyama, M; Morisawa, N; Satoh, JI; Yokoo, T1
Brunetto, MR; Chayama, K; Gadano, A; Gerken, G; Ghesquiere, W; Heo, J; Kumada, H; Lawitz, EJ; Levin, J; Linaberry, M; Liu, Z; McPhee, F; Noviello, S; Peng, CY; Pol, S; Reddy, KR; Silva, M; Strasser, SI; Thuluvath, PJ; Toyota, J; Yang, R1
Hess, KR; Hong, DS; Meric-Bernstam, F; Sen, S; Subbiah, V1
Álvarez-Larrán, A; Angona, A; Bellosillo, B; Besses, C; Camacho, L; Fernández-Rodríguez, C; Longarón, R; Senín, A1
Angus, PW; George, J; Gow, P; Jeffrey, G; Mason, S; McCaughan, GW; Mitchell, J; Morales, B; Parker, FC; Roberts, SK; Strasser, SI; Tallis, C; Thompson, AJ; Thwaites, PA; Wigg, A1
Akagi, A; Iwasaki, Y; Kitamoto, T; Mimuro, M; Yamada, M; Yoshida, M1
Chang, F; Duan, CA; Jin, X; Lu, Y1
Anthony, DC; Claridge, TDW; Jagielowicz, M; Probert, F; Simmons, A; Travis, S; Walsh, A; Yeo, T1
Azizi, M; Barreiros, AP; Birklein, F; Emrich, T; Galle, PR; Geber, C; Heise, M; Hoppe-Lotichius, M; Lang, H; Mittler, J; Otto, G; Schad, A; Schmid, JC; Vollmar, J; Weyer, V; Zimmermann, T1
Bregy, L; Bruderer, T; Eiffert, L; Engler, A; Gaugg, MT; Kohler, M; Nussbaumer-Ochsner, Y; Sinues, P; Zenobi, R1
Chen, XX; Feng, XL; Gao, L; Ren, HL; Wang, JL; Xiao, JH; Zhang, JH1
Fang, S; He, H; Hua, Y; Huang, Y; Li, R; Liang, S; Liu, P; Tian, Y; Xu, F; Yang, X; Yuan, Y; Zhang, Z1
Campbell, NR; De Oliveira, E; de Wilde, RF; Hidalgo, M; Korangath, P; Maitra, A; Pai, SG; Rajeshkumar, NV; Rasheed, ZA; Streppel, MM; Yabuuchi, S1
Amano, T; Harada, K; Ichimiya, S; Ishii, H; Kanashiro, M; Kobayashi, M; Kurebayashi, N; Marui, N; Murohara, T; Sone, T; Suzuki, S; Tsuboi, H; Uetani, T; Yoshikawa, D1
Ge, Y; Hou, J; Jin, B; Li, S; Liu, Z; Shi, M; Xie, H; Zhang, H1
Chan, J; Coelho, T; Conceiçao, I; Cruz, MW; da Silva, AM; Grogan, DR; Kelly, JW; Labaudinière, R; Maia, LF; Packman, J; Planté-Bordeneuve, V; Schmidt, HH; Suhr, OB; Trigo, P1
Cheung, AK; Huang, Y; Liu, X; Zhou, G1
Chen, F; Cheng, G; Fang, Y; Guo, Y; Li, H; Liu, D; Liu, F; Liu, L; Liu, Z; Margetts, P; Tang, L; Zhao, Z1
Dirnhofer, S; Duek, A; Grisouard, J; Hao-Shen, H; Kubovcakova, L; Shimizu, T; Skoda, RC1
Andersson, K; Avorn, J; Brennan, T; Choudhry, NK; Krumme, AA; Matlin, OS; Najafzadeh, M; Shrank, WH1
Adlard, P; Bjurstrom, N; Brandner, S; Caine, D; Collinge, J; Druyeh, R; Hummerich, H; Hyare, H; Jaunmuktane, Z; Lowe, J; Mead, S; Norsworthy, P; Rudge, P; Wadsworth, JD1
Gimeno-Ballester, V; Mar, J; San Miguel, R1
Alvarez-Twose, I; Caldas, C; Escribano, L; Garcia-Montero, AC; Jara-Acevedo, M; Matito, A; Mayado, A; Morgado, JM; Muñiz, C; Muñoz-Gonzalez, JI; Orfao, A; Sanchez-Muñoz, L; Teodosio, C1
Benedict, JJ; DeConti, R; Gibney, GT; Gonzalez, RJ; Kudchadkar, RR; McCardle, T; Messina, JL; Sloot, S; Smalley, KS; Sondak, VK; Turner, LM; Weber, JS; Zager, JS1
Gonzalez, YS; Johnson, S; Juday, T; Misurski, D; Parisé, H; Saab, S; Virabhak, S; Wang, A1
Andreu-Serra, H; Buades-Reinés, J; Cisneros-Barroso, E; Gallego-Lezaún, C; Raya-Cruz, M; Ripoll-Vera, T; Usón-Martín, M1
Ambler, K; Casolari, DA; D'Andrea, RJ; Nguyen, T; Ross, DM; Tiong, IS; Van Velzen, MJ1
Heger, E; Inden, S; Kaiser, R; Kalaghatgi, P; Knops, E; Neumann-Fraune, M; Schübel, N; Sierra, S1
Barbosa, MR; Cagni, FC; Campêlo, CLDC; Coimbra, DG; Gomes de Andrade, T; Júnior, COG; Júnior, LGO; Neto, ABS; Ribeiro, AM; Silva, RH1
Aftimos, P; Awada, A; Cesari, R; Curigliano, G; Dees, EC; Huang, B; Jiang, Y; Kern, KA; Locatelli, MA; LoRusso, PM; Pegram, MD; Shaik, MN1
Fujisaka, Y; Inoue, J; Kakazu, E; Kanno, A; Kobayashi, T; Kogure, T; Miura, M; Morosawa, T; Nakamura, T; Ninomiya, M; Shimosegawa, T; Takai, S; Umetsu, T; Wakui, Y1
Horiguchi, N; Hosonuma, K; Kakizaki, S; Kobayashi, T; Kusano, M; Ohnishi, H; Okamoto, H; Sato, K; Takakusagi, S; Yamada, M; Yamazaki, Y1
Bethel, M; Boolell, M; Califf, RM; Duggal, A; Haffner, SM; Holman, RR; McMurray, J1
Aoki, M; Fujiwara, Y; Makino, H; Miyake, T; Morishita, R; Nishimura, M; Shiraya, S; Yamakawa, S1
Hall, J; Johnstone, EC; Lawrie, SM; McIntosh, AM; McKirdy, J; Mirakhur, A; Moorhead, TW; Stanfield, AC; Sussmann, JE1
Geshi, E; Katagiri, T; Mochizuki, S; Nakano, H; Nanjyo, S; Sato, N; Shibata, T; Suzuki, H; Takano, T; Tanaka, K; Yagi, H; Yamazaki, J1
Miura, T; Yuda, S1
Amyere, M; Girardot, M; Knoops, L; Michaux, L; Selleslag, D; van Hees, J1
Braga, MF; Leiter, LA1
Fan, Z; Gao, L; Ge, J; Jia, J; Li, Y; Paajanen, V; Su, C; Sun, A; Wang, K; Wang, S; Yang, Z; Zou, Y1
Bourgoun, M; Califf, RM; Ghali, JK; Hassanein, AH; Hung, CL; Køber, L; Pfeffer, MA; Shin, SH; Solomon, SD; Uno, H; Velazquez, EJ; Verma, A1
Krack, L; Kretzschmar, H; Meissner, B; Redyk, K; Roeber, S; Schmidt, C; von Ahsen, N; Zerr, I1
Cahn, P; Grinsztejn, B; Kaul, R; Raboud, JM; Tan, DH; Walmsley, SL1
Dal Cin, P; Hernandez, JM; Kuo, FC; Leon, A; Longtine, JA; Staropoli, JF1
Coral, S; Fratta, E; Maio, M; Parisi, G; Sigalotti, L1
Ahn, CM; Choi, SC; Hong, SJ; Kim, JS; Lim, DS; Park, JH1
Amato, MC; Bommarito, A; Carina, V; Carissimi, E; Criscimanna, A; Di Blasi, F; Galluzzo, A; Giordano, C; Latteri, MA; Modica, G; Pitrone, M; Pizzolanti, G; Richiusa, P; Rodolico, V; Spinelli, G; Zerilli, M; Zito, G1
Blevins, J; Chen, W; Cohen, M; Cohen, Y; Haldiman, T; Kim, C; Safar, JG; Sy, MS1
Li, B; Oite, T; Qi, SH; Song, SM; Wang, CC; Xing, L; Yang, BF1
Amigoni, M; Califf, R; Køber, L; Levine, RA; McMurray, JJ; Meris, A; Pfeffer, MA; Solomon, SD; Thune, JJ; Velazquez, E; Verma, A1
Aarseth, JH; Celius, EG; Harbo, HF; Landrø, NI; Lie, BA; Lorentzen, ÅR; Mero, IL; Myhr, KM; Sandvik, L; Smestad, C1
Altieri, PI; Cangiano, JL; Crespo, MJ; Escobales, N1
Aono, J; Higaki, J; Horiuchi, M; Inoue, K; Iwai, M; Nagai, T; Nishimura, K; Ogimoto, A; Okayama, H; Suzuki, J1
Chen, B; Du, G; Guo, J; Li, X; Qiang, G; Shi, L; Xuan, Q; Yang, H; Yang, X; Zhang, H; Zhang, L; Zhou, D; Zu, M1
Drake, AL; Emery, S; Farquhar, C; John-Stewart, GC; Kiarie, JN; Matemo, DN; Ongecha-Owuor, F; Overbaugh, J; Richardson, B; Roxby, AC; Wald, A1
Cohrs, R; Gilden, D; Mahalingam, R; Nagel, MA; Schmid, DS; Silver, B1
Yiu, G; Young, LH1
Aritomi, S; Konda, T; Niinuma, K; Nitta, K; Ogawa, T1
Demant, A; El Arbi, S; Horneff, G; Kohlschmidt, N1
Endoh, M; Ideura, T; Kamata, K; Kimura, K; Suzuki, D; Tamura, K; Toya, Y; Umemura, S; Yasuda, T; Yoshimura, A1
Bitla, AR; Kumar, MA; Kumar, VS; Manohar, SM; Narasimha, SR; Raju, KV1
Brozinick, JT; Grove, K; Hawkins, E; Hoang Bui, H; Kievit, P; Kuo, MS; Tan, B1
Benigni, A; Donadoni, C; Fassi, A; Gagliardini, E; Lepre, MS; Remuzzi, A; Remuzzi, G; Sangalli, F1
Griffiths, PD1
Inagaki, K; Iwanaga, Y; Kihara, Y; Mochly-Rosen, D; Onozawa, Y; Sarai, N; Takenaka, H1
Doh-Ura, K; Hirata, A; Kamakura, K; Motoyoshi, K; Nishida, T; Tokumaru, AM1
Bertocchi, F; Ceconi, C; De Tommasi, E; Ferrari, R; Francolini, G; Guida, P; Iacoviello, M; Massari, F; Pitzalis, MV; Rizzon, P; Romito, R1
Bai, XF; Du, P; Guan, K; Li, O; Lin, S; Liu, X; Liu, Y; Rammohan, K; Robinson, N; Scarberry, B; Yin, L; You, M; Zheng, P; Zhou, Q1
Crijns, HJ; Folkeringa, RJ; Pinto, YM1
Jung, G; Link, J; Ludolph, AC; Reuter, A; Selzle, M; Völkel, H; Walk, T1
Bai, YM; Chen, JY; Lai, IC; Liao, DL; Lin, CC; Lin, CY; Liou, YJ; Wang, YC; Yu, SC1
An, HJ; Jung, MY; Kang, H; Kim, NK; Kim, SG; Kim, SH; Lee, KP; Lee, KS; Oh, D; Park, MJ1
DeKosky, ST; Desai, P; Kamboh, MI; Nebes, R1
Abrahamsson, PA; Ahlgren, G; Gadaleanu, V; Giwercman, A; Giwercman, YL1
Arai, T; Hara, K; Honda, H; Hosoi, T; Ito, YM; Kadowaki, T; Kameyama, S; Kitamura, T; Mamun, MR; Ohta, N; Ozeki, T; Sawabe, M; Suzuki, M; Takahashi, S; Takeuchi, T; Yamada, Y; Yanagihara, Y1
Datz, C; Ferenci, P; Hellerbrand, C; Kraus, MR; Norgauer, W; Osterreicher, CH; Schuppan, D; Stickel, F; Wölfel, M; Wrba, F1
Brownlow, N; Dibb, NJ; Domin, J; Taylor, JR1
Bech, E; Haahr, S; Hansen, HJ; Höllsberg, P; Jakobsen, J; Kusk, M1
Cho, H; Choi, BY; Hahn, DS; Ihm, C; Ju, H; Kang, C; Kim, JB; Kim, WH; Kim, YS; Noh, SM1
Anand, IS; Barlera, S; Carretta, E; Cohn, JN; Latini, R; Maggioni, AP; Masson, S; Staszewsky, L; Tan, LB; Tognoni, G; Vago, T; Wong, M1
Berho, M; Elliot, SJ; Plati, AR; Potier, M; Striker, GE; Striker, LJ; Zeng, YJ; Zheng, F1
Chen, N; Hao, L; Sun, G; Wang, W; Wu, K; Zhang, Y; Zhou, T1
Abbe, P; Bahadoran, P; Bailet, O; Ballotti, R; Baron, V; Bertolotto, C; Gaggioli, C; Ortonne, JP; Robert, G; Spadafora, A; Tartare-Deckert, S1
Khan, F; Kumagai, N; Mahmood, J; Morioka, T; Oite, T; Okada, S1
Coll, JR; Estacio, RO; Schrier, RW; Tran, ZV1
Fujita, K; Inamori, M; Iwasaki, T; Kirikoshi, H; Maeyama, S; Mawatari, H; Nakajima, A; Nozaki, Y; Saito, S; Takahashi, H; Terauchi, Y; Wada, K; Yoneda, M1
Wilkinson, E1
Hirokawa, M; Ito, Y; Miyauchi, A; Takano, T; Yoshida, H1
Antinori, A; Bertoli, A; Ceccherini-Silberstein, F; Forbici, F; Liuzzi, G; Lorenzini, P; Marconi, P; Mosti, S; Narciso, P; Perno, CF; Tozzi, V; Trotta, MP; Zaccarelli, M1
Cohn, JN; Duprez, DA; Florea, ND; Jones, K1
Victor, RG1
Cheung, M; Madhunapantula, SV; Robertson, GP; Sharma, A1
Itin, PH; Lautenschlager, S1
Bodsworth, NJ; Borelli, S; Crooks, RJ; Esmann, J; Gibb, A; Ingamells, AJ; Paavonen, J; Strand, A; Uexkull, N; Vejlsgaard, G; Worm, AM1
Brouwer, M; Coutinho, RA; de Roda Husman, AM; Goudsmit, J; Schuitemaker, H; van Rij, RP1
Goldstein, S; Levine, TB; Mishima, T; Sabbah, HN; Sharov, VG; Shimoyama, H; Tanimura, M1
de Ana, AM; Martínez-A, C; Mellado, M; Rodríguez-Frade, JM; Vila-Coro, AJ1
Robinson, RA; Yoo, J1
Chu, W; Harvie, S; Ho, M; Jewett, MA; Nam, RK; Narod, SA; Sweet, J; Toi, A; Trachtenberg, J; Vesprini, D1
Platz, EA1
Cooper, ME; Gibbs, NJ; Kelly, DJ; Skinner, SL; Wilkinson-Berka, JL1
Allen, TJ; Bertram, JF; Cooper, ME; Gilbert, RE; Hulthen, UL; Kelly, DJ; Mifsud, SA; Wilkinson-Berka, JL1
Bernasconi, E; Gobbi, C; Merenda, C; Städler, C; Tosi, C1

Reviews

4 review(s) available for valine and Disease Exacerbation

ArticleYear
Role of renin-angiotensin system blockade in patients with diabetes mellitus.
    The American journal of cardiology, 2009, Sep-15, Volume: 104, Issue:6

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Diabetes Mellitus; Diabetes Mellitus, Type 2; Disease Progression; Endothelium, Vascular; Humans; Ramipril; Renin-Angiotensin System; Rosiglitazone; Tetrazoles; Thiazolidinediones; Valine; Valsartan; Vasodilation; Ventricular Function

2009
Tomorrow's challenges for herpesvirus management: potential applications of valacyclovir.
    The Journal of infectious diseases, 2002, Oct-15, Volume: 186 Suppl 1

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Antiviral Agents; Arteriosclerosis; Bone Marrow Transplantation; Clinical Trials as Topic; Disease Progression; Herpesviridae; Herpesviridae Infections; Humans; Multiple Sclerosis; Organ Transplantation; Postoperative Complications; Valacyclovir; Valine

2002
Pathophysiology of target-organ disease: does angiotensin II remain the key?
    Journal of clinical hypertension (Greenwich, Conn.), 2007, Volume: 9, Issue:11 Suppl 4

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Disease Progression; Humans; Hypertension; Losartan; Myocardial Infarction; Renin; Renin-Angiotensin System; Stroke; Tetrazoles; Treatment Outcome; Valine; Valsartan

2007
Viral lesions of the mouth in HIV-infected patients.
    Dermatology (Basel, Switzerland), 1997, Volume: 194, Issue:1

    Topics: 2-Aminopurine; Acyclovir; AIDS-Related Opportunistic Infections; Anti-HIV Agents; Cytomegalovirus Infections; Disease Progression; Famciclovir; Foscarnet; Ganciclovir; Herpesviridae Infections; Herpesvirus 1, Human; Herpesvirus 2, Human; Herpesvirus 4, Human; Herpesvirus 8, Human; Humans; Leukoplakia, Hairy; Lymphoma, B-Cell; Lymphoma, T-Cell; Molluscum Contagiosum; Mouth Diseases; Mouth Neoplasms; Oral Ulcer; Prodrugs; Sarcoma, Kaposi; Stomatitis, Herpetic; Tumor Virus Infections; Valacyclovir; Valine; Virus Diseases; Warts

1997

Trials

17 trial(s) available for valine and Disease Exacerbation

ArticleYear
Impact of angiotensin II receptor blocker therapy (olmesartan or valsartan) on coronary atherosclerotic plaque volume measured by intravascular ultrasound in patients with stable angina pectoris.
    The American journal of cardiology, 2013, Aug-01, Volume: 112, Issue:3

    Topics: Aged; Aged, 80 and over; Angina Pectoris; Angioplasty, Balloon, Coronary; Angiotensin II Type 1 Receptor Blockers; Combined Modality Therapy; Coronary Artery Disease; Disease Progression; Double-Blind Method; Female; Humans; Hypertension; Image Interpretation, Computer-Assisted; Imidazoles; Long-Term Care; Male; Middle Aged; Tetrazoles; Ultrasonography, Interventional; Valine; Valsartan

2013
Treatment of diabetic nephropathy with Tripterygium wilfordii Hook F extract: a prospective, randomized, controlled clinical trial.
    Journal of translational medicine, 2013, May-31, Volume: 11

    Topics: Adult; Aged; Diabetic Nephropathies; Disease Progression; Female; Follow-Up Studies; Glomerular Filtration Rate; Humans; Male; Middle Aged; Phytotherapy; Plant Extracts; Prospective Studies; Tetrazoles; Treatment Outcome; Tripterygium; Valine; Valsartan

2013
Long-term effects of tafamidis for the treatment of transthyretin familial amyloid polyneuropathy.
    Journal of neurology, 2013, Volume: 260, Issue:11

    Topics: Adult; Aged; Amyloid Neuropathies, Familial; Benzoxazoles; Disease Progression; Drug Administration Schedule; Female; Follow-Up Studies; Humans; International Cooperation; Male; Methionine; Middle Aged; Mutation; Prealbumin; Quality of Life; Time Factors; Valine; Young Adult

2013
Valsartan combined with clopidogrel and/or leflunomide for the treatment of progressive immunoglobulin A nephropathy.
    Nephrology (Carlton, Vic.), 2015, Volume: 20, Issue:2

    Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Biomarkers; China; Clopidogrel; Creatinine; Disease Progression; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Glomerulonephritis, IGA; Humans; Immunosuppressive Agents; Isoxazoles; Kidney; Leflunomide; Male; Platelet Aggregation Inhibitors; Proteinuria; Tetrazoles; Ticlopidine; Time Factors; Treatment Outcome; Valine; Valsartan

2015
Phase I study of the gamma secretase inhibitor PF-03084014 in combination with docetaxel in patients with advanced triple-negative breast cancer.
    Oncotarget, 2017, Jan-10, Volume: 8, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Disease Progression; Docetaxel; Dose-Response Relationship, Drug; Female; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neutropenia; Taxoids; Tetrahydronaphthalenes; Triple Negative Breast Neoplasms; Valine; Vomiting

2017
Prevention of diabetes and cardiovascular disease in patients with impaired glucose tolerance: rationale and design of the Nateglinide And Valsartan in Impaired Glucose Tolerance Outcomes Research (NAVIGATOR) Trial.
    American heart journal, 2008, Volume: 156, Issue:4

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Cyclohexanes; Diabetic Angiopathies; Disease Progression; Double-Blind Method; Glucose Intolerance; Humans; Hypoglycemic Agents; Life Style; Nateglinide; Outcome Assessment, Health Care; Phenylalanine; Research Design; Tetrazoles; Valine; Valsartan

2008
Inhibitory effect of valsartan against progression of left ventricular dysfunction after myocardial infarction: T-VENTURE study.
    Circulation journal : official journal of the Japanese Circulation Society, 2009, Volume: 73, Issue:5

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Asian People; Disease Progression; Female; Humans; Japan; Male; Middle Aged; Myocardial Infarction; Stroke Volume; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan; Ventricular Dysfunction, Left; Ventricular Remodeling

2009
Can herpes simplex virus type 2 suppression slow HIV disease progression: a study protocol for the VALacyclovir In Delaying Antiretroviral Treatment Entry (VALIDATE) trial.
    Trials, 2010, Nov-24, Volume: 11

    Topics: Acyclovir; Antiviral Agents; Clinical Protocols; Disease Progression; Herpesvirus 2, Human; HIV Infections; HIV-1; Humans; Valacyclovir; Valine; Viral Load

2010
Telmisartan reduces neointima volume and pulse wave velocity 8 months after zotarolimus-eluting stent implantation in hypertensive type 2 diabetic patients.
    Heart (British Cardiac Society), 2011, Volume: 97, Issue:17

    Topics: Adiponectin; Aged; Ankle Brachial Index; Anti-Inflammatory Agents; Benzimidazoles; Benzoates; C-Reactive Protein; Coronary Stenosis; Diabetes Mellitus, Type 2; Disease Progression; Drug-Eluting Stents; Female; Follow-Up Studies; Humans; Hypertension; Interleukin-6; Male; Middle Aged; Neointima; Prospective Studies; Single-Blind Method; Sirolimus; Telmisartan; Tetrazoles; Time Factors; Treatment Outcome; Tumor Necrosis Factor-alpha; Ultrasonography, Interventional; Valine; Valsartan

2011
Mechanisms and predictors of mitral regurgitation after high-risk myocardial infarction.
    Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, 2012, Volume: 25, Issue:5

    Topics: Adult; Age Factors; Aged; Angiotensin-Converting Enzyme Inhibitors; Captopril; Disease Progression; Echocardiography, Doppler, Color; Electrocardiography; Female; Follow-Up Studies; Humans; Male; Middle Aged; Mitral Valve Insufficiency; Monitoring, Physiologic; Multivariate Analysis; Myocardial Infarction; Predictive Value of Tests; Prospective Studies; Reference Values; Reproducibility of Results; Risk Assessment; ROC Curve; Severity of Illness Index; Sex Factors; Statistics, Nonparametric; Stroke Volume; Tetrazoles; Time Factors; Valine; Valsartan; Ventricular Dysfunction, Left; Ventricular Remodeling

2012
Effects of valacyclovir on markers of disease progression in postpartum women co-infected with HIV-1 and herpes simplex virus-2.
    PloS one, 2012, Volume: 7, Issue:6

    Topics: Acyclovir; Antiviral Agents; Biomarkers; CD4 Antigens; Disease Progression; Female; Herpes Genitalis; Herpesvirus 2, Human; HIV Infections; HIV-1; Humans; Kenya; Linear Models; Nevirapine; Postpartum Period; Pregnancy; RNA, Viral; Valacyclovir; Valine; Zidovudine

2012
Effects of valsartan on progression of kidney disease in Japanese hypertensive patients with advanced, predialysis, chronic kidney disease: Kanagawa Valsartan Trial (KVT).
    Hypertension research : official journal of the Japanese Society of Hypertension, 2013, Volume: 36, Issue:3

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Asian People; Blood Pressure; Comorbidity; Creatinine; Disease Progression; Female; Humans; Hypertension; Japan; Male; Middle Aged; Proteinuria; Renal Insufficiency, Chronic; Renal Replacement Therapy; Tetrazoles; Treatment Outcome; Valine; Valsartan

2013
Comparison of the effect of valsartan and lisinopril on autonomic nervous system activity in chronic heart failure.
    American heart journal, 2003, Volume: 146, Issue:5

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Autonomic Nervous System; Disease Progression; Double-Blind Method; Female; Heart Failure; Heart Rate; Humans; Lisinopril; Male; Middle Aged; Norepinephrine; Tetrazoles; Valine; Valsartan

2003
Presence of Epstein-Barr virus and human herpesvirus 6B DNA in multiple sclerosis patients: associations with disease activity.
    Acta neurologica Scandinavica, 2005, Volume: 112, Issue:6

    Topics: Acyclovir; Adult; Antiviral Agents; Disease Progression; DNA, Viral; Double-Blind Method; Female; Herpesvirus 4, Human; Herpesvirus 6, Human; Humans; Male; Multiple Sclerosis; Saliva; Statistics as Topic; Treatment Outcome; Valacyclovir; Valine; Viral Load

2005
Effect of intensive blood pressure control with valsartan on urinary albumin excretion in normotensive patients with type 2 diabetes.
    American journal of hypertension, 2006, Volume: 19, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Cardiovascular Diseases; Colorado; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Disease Progression; Female; Follow-Up Studies; Humans; Kidney Function Tests; Male; Middle Aged; Prospective Studies; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan

2006
Beneficial effects of valsartan in asymptomatic individuals with vascular or cardiac abnormalities: the DETECTIV Pilot Study.
    Journal of the American College of Cardiology, 2007, Aug-28, Volume: 50, Issue:9

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Cardiovascular Diseases; Comorbidity; Coronary Artery Disease; Disease Progression; Double-Blind Method; Exercise Test; Female; Fluorescein Angiography; Health Status Indicators; Heart Diseases; Humans; Hypertension; Male; Middle Aged; Natriuretic Peptide, Brain; Pilot Projects; Predictive Value of Tests; Tetrazoles; Valine; Valsartan

2007
Valaciclovir versus aciclovir in patient initiated treatment of recurrent genital herpes: a randomised, double blind clinical trial. International Valaciclovir HSV Study Group.
    Genitourinary medicine, 1997, Volume: 73, Issue:2

    Topics: Acyclovir; Adolescent; Adult; Aged; Antiviral Agents; Disease Progression; Double-Blind Method; Female; Herpes Genitalis; Humans; Male; Middle Aged; Pain Measurement; Proportional Hazards Models; Recurrence; Self Medication; Time Factors; Valacyclovir; Valine; Virus Shedding; Wound Healing

1997

Other Studies

89 other study(ies) available for valine and Disease Exacerbation

ArticleYear
The associations of serum valine with mild cognitive impairment and Alzheimer's disease.
    Aging clinical and experimental research, 2022, Volume: 34, Issue:8

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Brain; Cognitive Dysfunction; Disease Progression; Glucose; Humans; Positron-Emission Tomography; tau Proteins; Valine

2022
Impaired Amino Acid Metabolism and Its Correlation with Diabetic Kidney Disease Progression in Type 2 Diabetes Mellitus.
    Nutrients, 2022, Aug-15, Volume: 14, Issue:16

    Topics: Asparagine; Betaine; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Progression; Follow-Up Studies; Humans; Isoleucine; Methionine; Prospective Studies; Valine

2022
Hepatitis C therapy with direct antiviral agents in patients with advanced chronic kidney disease: real-world experience of the German Hepatitis C-Registry (Deutsches Hepatitis C-Register).
    European journal of gastroenterology & hepatology, 2019, Volume: 31, Issue:11

    Topics: 2-Naphthylamine; Acute Disease; Adult; Aged; Anemia; Anilides; Antiviral Agents; Benzimidazoles; Carbamates; Cyclopropanes; Disease Progression; Drug Therapy, Combination; Female; Fluorenes; Germany; Glomerular Filtration Rate; Hepatitis C, Chronic; Humans; Hypertension; Imidazoles; Lactams, Macrocyclic; Liver Cirrhosis; Macrocyclic Compounds; Male; Middle Aged; Pleural Effusion; Proline; Pyrrolidines; Registries; Renal Insufficiency, Chronic; Ribavirin; Ritonavir; RNA, Viral; Severity of Illness Index; Simeprevir; Sofosbuvir; Sulfonamides; Sustained Virologic Response; Treatment Outcome; Uracil; Uridine Monophosphate; Valine

2019
Daclatasvir and Sofosbuvir Mitigate Hepatic Fibrosis Through Downregulation of TNF-α / NF-κB Signaling Pathway.
    Current molecular pharmacology, 2020, Volume: 13, Issue:4

    Topics: Animals; Carbamates; Carbon Tetrachloride; Disease Progression; Down-Regulation; Hepatic Stellate Cells; Imidazoles; Liver; Liver Cirrhosis; Male; NF-kappa B; Proto-Oncogene Proteins c-bcl-2; Pyrrolidines; Rats, Wistar; Sofosbuvir; Tumor Necrosis Factor-alpha; Valine

2020
Multiple BCL2 mutations cooccurring with Gly101Val emerge in chronic lymphocytic leukemia progression on venetoclax.
    Blood, 2020, 03-05, Volume: 135, Issue:10

    Topics: Amino Acid Substitution; Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Cohort Studies; Disease Progression; DNA Mutational Analysis; Drug Resistance, Neoplasm; Gene Frequency; Glycine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Models, Molecular; Mutation; Mutation Rate; Proto-Oncogene Proteins c-bcl-2; Sulfonamides; Tumor Cells, Cultured; Valine

2020
Fecal Metabolites Were Altered, Identified as Biomarkers and Correlated With Disease Activity in Patients With Systemic Lupus Erythematosus in a GC-MS-Based Metabolomics Study.
    Frontiers in immunology, 2020, Volume: 11

    Topics: Adult; Biomarkers; Disease Progression; Erucic Acids; Feces; Female; Gas Chromatography-Mass Spectrometry; Humans; Lupus Erythematosus, Systemic; Male; Metabolomics; Middle Aged; Phenols; ROC Curve; Valine

2020
Effectiveness of a fixed combination formula of ombitasvir/paritaprevir/ritonavir for hepatitis C virus infection in patients on maintenance haemodialysis.
    Nephrology (Carlton, Vic.), 2017, Volume: 22, Issue:7

    Topics: Aged; Aged, 80 and over; Anilides; Antiviral Agents; Carbamates; Cyclopropanes; Disease Progression; Drug Combinations; Drug Compounding; Female; Genotype; Hepacivirus; Hepatitis C; Humans; Japan; Lactams, Macrocyclic; Liver Cirrhosis; Macrocyclic Compounds; Male; Middle Aged; Proline; Renal Dialysis; Renal Insufficiency, Chronic; Ritonavir; RNA, Viral; Sulfonamides; Sustained Virologic Response; Time Factors; Treatment Outcome; Valine; Viral Load

2017
Long-term follow-up of clinical trial patients treated for chronic HCV infection with daclatasvir-based regimens.
    Liver international : official journal of the International Association for the Study of the Liver, 2018, Volume: 38, Issue:5

    Topics: Adult; Aged; Antiviral Agents; Carbamates; Disease Progression; Drug Resistance, Viral; Drug Therapy, Combination; Female; Follow-Up Studies; Hepacivirus; Hepatitis C, Chronic; Humans; Imidazoles; Liver Cirrhosis; Male; Middle Aged; Pyrrolidines; RNA, Viral; Sustained Virologic Response; Valine; Viral Load; Young Adult

2018
Co-occurring Genomic Alterations and Association With Progression-Free Survival in BRAFV600-Mutated Nonmelanoma Tumors.
    Journal of the National Cancer Institute, 2017, 10-01, Volume: 109, Issue:10

    Topics: Amino Acid Substitution; Disease Progression; Disease-Free Survival; Drug Resistance, Neoplasm; Genetic Association Studies; Humans; Molecular Targeted Therapy; Mutation; Neoplasms; Prognosis; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Valine

2017
Non-driver mutations in patients with JAK2V617F-mutated polycythemia vera or essential thrombocythemia with long-term molecular follow-up.
    Annals of hematology, 2018, Volume: 97, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Alleles; Amino Acid Substitution; Cell Transformation, Neoplastic; Cytogenetic Analysis; Disease Progression; Female; Follow-Up Studies; Gene Frequency; Humans; Janus Kinase 2; Male; Middle Aged; Mutation, Missense; Phenylalanine; Polycythemia Vera; Thrombocythemia, Essential; Valine

2018
Sofosbuvir and daclatasvir therapy in patients with hepatitis C-related advanced decompensated liver disease (MELD ≥ 15).
    Alimentary pharmacology & therapeutics, 2018, Volume: 47, Issue:3

    Topics: Antiviral Agents; Australia; Carbamates; Compassionate Use Trials; Disease Progression; Drug Therapy, Combination; Female; Hepatitis C, Chronic; Humans; Imidazoles; Liver Cirrhosis; Liver Transplantation; Male; Middle Aged; Pyrrolidines; Retrospective Studies; Ribavirin; Sofosbuvir; Survival Analysis; Treatment Outcome; Valine

2018
Pathological progression of genetic Creutzfeldt-Jakob disease with a PrP V180I mutation.
    Prion, 2018, 01-02, Volume: 12, Issue:1

    Topics: Aged; Aged, 80 and over; Brain; Creutzfeldt-Jakob Syndrome; Disease Progression; Gliosis; Glutamic Acid; Humans; Isoleucine; Methionine; Middle Aged; Mutation; Prion Proteins; Vacuoles; Valine

2018
Cost-effectiveness of daclatasvir plus asunaprevir for chronic hepatitis C genotype 1b treatment-naïve patients in China.
    PloS one, 2018, Volume: 13, Issue:4

    Topics: Adult; Antiviral Agents; Carbamates; China; Cohort Studies; Cost-Benefit Analysis; Disease Progression; Female; Genotype; Health Care Costs; Hepatitis C, Chronic; Humans; Imidazoles; Interferon-alpha; Isoquinolines; Male; Markov Chains; Middle Aged; Monte Carlo Method; Polyethylene Glycols; Probability; Pyrrolidines; Quality of Life; Recombinant Proteins; Ribavirin; Sensitivity and Specificity; Sulfonamides; Treatment Outcome; Valine

2018
Plasma Nuclear Magnetic Resonance Metabolomics Discriminates Between High and Low Endoscopic Activity and Predicts Progression in a Prospective Cohort of Patients With Ulcerative Colitis.
    Journal of Crohn's & colitis, 2018, Nov-15, Volume: 12, Issue:11

    Topics: Adolescent; Adult; Amino Acids; Blood Glucose; Colitis, Ulcerative; Disease Progression; Endoscopy, Gastrointestinal; Female; Histidine; Humans; Isoleucine; Lipoproteins; Lysine; Magnetic Resonance Spectroscopy; Male; Metabolomics; Middle Aged; Phenylalanine; Predictive Value of Tests; Prospective Studies; Severity of Illness Index; Single-Blind Method; Tyrosine; Valine; Young Adult

2018
Progression of transthyretin (TTR) amyloidosis in donors and recipients after domino liver transplantation-a prospective single-center cohort study.
    Transplant international : official journal of the European Society for Organ Transplantation, 2018, Volume: 31, Issue:11

    Topics: Adult; Aged; Amyloid Neuropathies, Familial; Biopsy; Child; Databases, Factual; Disease Progression; Echocardiography; Female; Heart Rate; Humans; Liver Failure; Liver Transplantation; Living Donors; Male; Methionine; Middle Aged; Prospective Studies; Time Factors; Treatment Outcome; Valine

2018
Molecular breath analysis supports altered amino acid metabolism in idiopathic pulmonary fibrosis.
    Respirology (Carlton, Vic.), 2019, Volume: 24, Issue:5

    Topics: Aged; Alanine; Amino Acids; Area Under Curve; Biomarkers; Breath Tests; Case-Control Studies; Disease Progression; Exhalation; Female; Humans; Hydroxyproline; Idiopathic Pulmonary Fibrosis; Isoleucine; Leucine; Male; Middle Aged; ROC Curve; Spectrometry, Mass, Electrospray Ionization; Valine

2019
Combination of L-Arginine and L-Norvaline protects against pulmonary fibrosis progression induced by bleomycin in mice.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 113

    Topics: Administration, Oral; Animals; Arginine; Bleomycin; Disease Models, Animal; Disease Progression; Drug Therapy, Combination; Intraepithelial Lymphocytes; Lung; Male; Mice; Pulmonary Fibrosis; T-Lymphocytes, Regulatory; Th17 Cells; Valine

2019
Time Series Characteristics of Serum Branched-Chain Amino Acids for Early Diagnosis of Chronic Heart Failure.
    Journal of proteome research, 2019, 05-03, Volume: 18, Issue:5

    Topics: Animals; Area Under Curve; Biomarkers; Disease Models, Animal; Disease Progression; Early Diagnosis; Heart Failure; Leucine; Machine Learning; Male; Metabolome; Metabolomics; Myocardial Infarction; Rats; Rats, Sprague-Dawley; ROC Curve; Valine

2019
Notch signaling pathway targeted therapy suppresses tumor progression and metastatic spread in pancreatic cancer.
    Cancer letters, 2013, Jul-10, Volume: 335, Issue:1

    Topics: Animals; Antigens, CD; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Pancreatic Ductal; Cell Proliferation; Deoxycytidine; Disease Progression; Female; Gemcitabine; Humans; Liver Neoplasms; Lung Neoplasms; Mice; Mice, Nude; Molecular Targeted Therapy; Neoplastic Stem Cells; Pancreatic Neoplasms; Receptors, Notch; Signal Transduction; Tetrahydronaphthalenes; Tumor Burden; Tumor Cells, Cultured; Valine; Xenograft Model Antitumor Assays

2013
Valsartan slows the progression of diabetic nephropathy in db/db mice via a reduction in podocyte injury, and renal oxidative stress and inflammation.
    Clinical science (London, England : 1979), 2014, Volume: 126, Issue:10

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Progression; Extracellular Matrix Proteins; Fibronectins; Gene Expression Regulation; Inflammation; Intracellular Signaling Peptides and Proteins; Kidney; Kidney Cortex; Kidney Glomerulus; Membrane Proteins; Mice; Oxidative Stress; Plasminogen Activator Inhibitor 1; Podocytes; RNA, Messenger; Tetrazoles; Transforming Growth Factor beta1; Treatment Outcome; Valine; Valsartan; WT1 Proteins

2014
Deletion of Stat3 in hematopoietic cells enhances thrombocytosis and shortens survival in a JAK2-V617F mouse model of MPN.
    Blood, 2015, Mar-26, Volume: 125, Issue:13

    Topics: Amino Acid Substitution; Animals; Bone Marrow; Bone Marrow Neoplasms; Disease Models, Animal; Disease Progression; Gene Deletion; Hematopoietic Stem Cells; Janus Kinase 2; Mice; Mice, Inbred C57BL; Mice, Transgenic; Myeloproliferative Disorders; Phenylalanine; STAT3 Transcription Factor; Thrombocytosis; Valine

2015
Cost-effectiveness of novel regimens for the treatment of hepatitis C virus.
    Annals of internal medicine, 2015, Mar-17, Volume: 162, Issue:6

    Topics: Antiviral Agents; Benzimidazoles; Carbamates; Cost-Benefit Analysis; Disease Progression; Drug Costs; Drug Therapy, Combination; Fluorenes; Genotype; Hepacivirus; Hepatitis C, Chronic; Heterocyclic Compounds, 3-Ring; Humans; Imidazoles; Interferon-alpha; Patient-Specific Modeling; Pyrrolidines; Ribavirin; Sensitivity and Specificity; Simeprevir; Sofosbuvir; Sulfonamides; Uridine Monophosphate; Valine

2015
Iatrogenic CJD due to pituitary-derived growth hormone with genetically determined incubation times of up to 40 years.
    Brain : a journal of neurology, 2015, Volume: 138, Issue:Pt 11

    Topics: Adult; Brain; Codon; Creutzfeldt-Jakob Syndrome; Disease Progression; Drug Contamination; Electroencephalography; Female; Gene-Environment Interaction; Genotype; Growth Disorders; Homozygote; Human Growth Hormone; Humans; Iatrogenic Disease; Infectious Disease Incubation Period; Magnetic Resonance Imaging; Male; Methionine; Middle Aged; Prion Proteins; Prions; Retrospective Studies; Time Factors; United Kingdom; Valine

2015
Cost-effectiveness analysis of simeprevir with daclatasvir for non-cirrhotic genotype-1b-naïve patients plus chronic hepatitis C.
    Expert review of pharmacoeconomics & outcomes research, 2016, Volume: 16, Issue:2

    Topics: Adult; Aged; Antiviral Agents; Carbamates; Cost-Benefit Analysis; Disease Progression; Drug Therapy, Combination; Genotype; Health Care Costs; Hepacivirus; Hepatitis C, Chronic; Humans; Imidazoles; Markov Chains; Middle Aged; Pyrrolidines; Quality-Adjusted Life Years; Simeprevir; Valine

2016
KIT D816V-mutated bone marrow mesenchymal stem cells in indolent systemic mastocytosis are associated with disease progression.
    Blood, 2016, Feb-11, Volume: 127, Issue:6

    Topics: Adult; Amino Acid Substitution; Aspartic Acid; Bone Marrow Cells; Cell Lineage; Disease Progression; Female; Humans; Immunophenotyping; Male; Mastocytosis, Systemic; Mesenchymal Stem Cells; Mutation, Missense; Proto-Oncogene Proteins c-kit; Valine

2016
BRAF inhibition for advanced locoregional BRAF V600E mutant melanoma: a potential neoadjuvant strategy.
    Melanoma research, 2016, Volume: 26, Issue:1

    Topics: Amino Acid Substitution; Antineoplastic Combined Chemotherapy Protocols; Disease Progression; Female; Follow-Up Studies; Glutamic Acid; Humans; Imidazoles; Indoles; Male; Melanoma; Middle Aged; Molecular Targeted Therapy; Mutation, Missense; Neoadjuvant Therapy; Oximes; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Pyridones; Pyrimidinones; Retrospective Studies; Skin Neoplasms; Sulfonamides; Treatment Outcome; Valine; Vemurafenib

2016
Cost-Effectiveness of Genotype 1 Chronic Hepatitis C Virus Treatments in Patients Coinfected with Human Immunodeficiency Virus in the United States.
    Advances in therapy, 2016, Volume: 33, Issue:8

    Topics: 2-Naphthylamine; Adult; Anilides; Antiviral Agents; Benzimidazoles; Carbamates; Carcinoma, Hepatocellular; Cost-Benefit Analysis; Cyclopropanes; Disease Progression; Drug Therapy, Combination; Fluorenes; Genotype; Hepacivirus; Hepatitis C, Chronic; HIV Infections; Humans; Interferon-alpha; Lactams, Macrocyclic; Liver Cirrhosis; Liver Neoplasms; Macrocyclic Compounds; Markov Chains; Middle Aged; Polyethylene Glycols; Proline; Quality-Adjusted Life Years; Recombinant Proteins; Ribavirin; Ritonavir; Sofosbuvir; Sulfonamides; United States; Uracil; Valine

2016
Transthyretin familial amyloid polyneuropathy (TTR-FAP) in Mallorca: a comparison between late- and early-onset disease.
    Journal of the peripheral nervous system : JPNS, 2016, Volume: 21, Issue:4

    Topics: Adult; Age of Onset; Aged; Amyloid Neuropathies, Familial; Disease Progression; Female; Follow-Up Studies; Humans; Male; Methionine; Middle Aged; Mutation; Prealbumin; Retrospective Studies; Spain; Valine; Young Adult

2016
Masked polycythaemia vera is genetically intermediate between JAK2V617F mutated essential thrombocythaemia and overt polycythaemia vera.
    Blood cancer journal, 2016, 08-19, Volume: 6, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Asymptomatic Diseases; Cohort Studies; Disease Progression; Female; Genetic Predisposition to Disease; Humans; Janus Kinase 2; Male; Middle Aged; Mutation, Missense; Phenylalanine; Polycythemia Vera; Polymorphism, Single Nucleotide; Prodromal Symptoms; Thrombocythemia, Essential; Valine

2016
HCV Resistance Profile Evolution in a GT1b, DAA-Naive Patient Before, On, and After Failing Triple DAA Therapy.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2017, Volume: 15, Issue:2

    Topics: 2-Naphthylamine; Anilides; Antiviral Agents; Carbamates; Cyclopropanes; Disease Progression; Drug Combinations; Drug Resistance, Viral; Hepacivirus; Hepatitis C, Chronic; High-Throughput Nucleotide Sequencing; Humans; Lactams, Macrocyclic; Macrocyclic Compounds; Male; Middle Aged; Proline; Ribavirin; Ritonavir; RNA, Viral; Sulfonamides; Sustained Virologic Response; Treatment Failure; Uracil; Valine; Viral Nonstructural Proteins

2017
Association of BDNF Val66MET Polymorphism With Parkinson's Disease and Depression and Anxiety Symptoms.
    The Journal of neuropsychiatry and clinical neurosciences, 2017,Spring, Volume: 29, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anxiety; Brain-Derived Neurotrophic Factor; Depression; Disease Progression; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Humans; Male; Methionine; Middle Aged; Parkinson Disease; Polymorphism, Genetic; Valine

2017
Identification of Genotype 2 HCV in Serotype-1 Hepatitis C Patients Unresponsive to Daclatasvir plus Asunaprevir Treatment.
    The Tohoku journal of experimental medicine, 2017, Volume: 241, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Base Sequence; Carbamates; Disease Progression; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C; Humans; Imidazoles; Isoquinolines; Male; Middle Aged; Phylogeny; Pyrrolidines; Serotyping; Sulfonamides; Time Factors; Treatment Outcome; Valine; Viral Nonstructural Proteins

2017
Combination Therapy with Ombitasvir/Paritaprevir/Ritonavir for Dialysis Patients Infected with Hepatitis C Virus: A Prospective Multi-Institutional Study.
    The Tohoku journal of experimental medicine, 2017, Volume: 241, Issue:1

    Topics: Aged; Anilides; Carbamates; Cyclopropanes; Demography; Disease Progression; Drug Resistance, Viral; Drug Therapy, Combination; Hepacivirus; Hepatitis C, Chronic; Humans; Lactams, Macrocyclic; Macrocyclic Compounds; Male; Middle Aged; Proline; Renal Dialysis; Ritonavir; Sulfonamides; Valine

2017
Inhibition of experimental abdominal aortic aneurysm in a rat model by the angiotensin receptor blocker valsartan.
    International journal of molecular medicine, 2008, Volume: 22, Issue:6

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Blood Pressure; Disease Models, Animal; Disease Progression; Gene Expression Regulation; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neutrophil Infiltration; NF-kappa B; Pancreatic Elastase; Rats; Rats, Wistar; Tetrazoles; Ultrasonography; Valine; Valsartan

2008
Changes in gyrification over 4 years in bipolar disorder and their association with the brain-derived neurotrophic factor valine(66) methionine variant.
    Biological psychiatry, 2009, Aug-01, Volume: 66, Issue:3

    Topics: Adult; Analysis of Variance; Bipolar Disorder; Brain-Derived Neurotrophic Factor; Disease Progression; Electronic Data Processing; Female; Gene Frequency; Genotype; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Male; Methionine; Middle Aged; Neuropsychological Tests; Polymorphism, Single Nucleotide; Prefrontal Cortex; Valine

2009
Are treatment effects of ACEI and ARB in post-MI patients homogeneous?
    Circulation journal : official journal of the Japanese Circulation Society, 2009, Volume: 73, Issue:5

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Asian People; Disease Progression; Humans; Myocardial Infarction; Stroke Volume; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan; Ventricular Dysfunction, Left; Ventricular Remodeling

2009
Analysis of the progression of JAK2 V617F positive myeloproliferative neoplasms by single-nucleotide polymorphism array does not reveal a strong chromosomal instability.
    Cancer genetics and cytogenetics, 2009, Jul-15, Volume: 192, Issue:2

    Topics: Aged; Aged, 80 and over; Amino Acid Substitution; Chromosomal Instability; Disease Progression; Humans; Janus Kinase 2; Middle Aged; Myeloproliferative Disorders; Phenylalanine; Polymorphism, Single Nucleotide; Valine

2009
Molecular and clinical characterization of a novel SCN5A mutation associated with atrioventricular block and dilated cardiomyopathy.
    Circulation. Arrhythmia and electrophysiology, 2008, Jun-01, Volume: 1, Issue:2

    Topics: Adult; Alanine; Amino Acid Substitution; Asian People; Atrioventricular Block; Base Sequence; Cardiomyopathy, Dilated; Cell Line; Disease Progression; Electrocardiography; Electrophysiology; Exercise Test; Female; Hemodynamics; Humans; Male; Middle Aged; Molecular Sequence Data; Muscle Proteins; NAV1.5 Voltage-Gated Sodium Channel; Pedigree; Polymorphism, Single Nucleotide; Sodium Channels; Valine; Young Adult

2008
Mechanical dyssynchrony after myocardial infarction in patients with left ventricular dysfunction, heart failure, or both.
    Circulation, 2010, Mar-09, Volume: 121, Issue:9

    Topics: Aged; Analog-Digital Conversion; Angiotensin II Type 1 Receptor Blockers; Death; Disease Progression; Female; Follow-Up Studies; Heart Failure; Humans; Male; Middle Aged; Motion; Myocardial Contraction; Myocardial Infarction; Prognosis; Proportional Hazards Models; Stress, Mechanical; Tetrazoles; Ultrasonography; Valine; Valsartan; Ventricular Dysfunction, Left; Video Recording

2010
Clinical features of rapidly progressive Alzheimer's disease.
    Dementia and geriatric cognitive disorders, 2010, Volume: 29, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Apolipoprotein E4; Apolipoproteins E; Biomarkers; Codon; Disease Progression; Female; Gait; Gene Frequency; Heterozygote; Homozygote; Humans; Male; Methionine; Middle Aged; Muscle Rigidity; Myoclonus; Peptide Fragments; Polymorphism, Genetic; Prion Proteins; Prions; Retrospective Studies; Survival Analysis; tau Proteins; Time Factors; Valine

2010
Translocation t(1;9) is a recurrent cytogenetic abnormality associated with progression of essential thrombocythemia patients displaying the JAK2 V617F mutation.
    Leukemia research, 2011, Volume: 35, Issue:9

    Topics: Aged; Aged, 80 and over; Amino Acid Substitution; Chromosome Aberrations; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 9; Cohort Studies; Disease Progression; Female; Humans; Janus Kinase 2; Male; Middle Aged; Mutation, Missense; Phenylalanine; Recurrence; Thrombocythemia, Essential; Translocation, Genetic; Valine

2011
Stability of BRAF V600E mutation in metastatic melanoma: new insights for therapeutic success?
    British journal of cancer, 2011, Jul-12, Volume: 105, Issue:2

    Topics: Amino Acid Substitution; Disease Progression; Glutamic Acid; Humans; Melanoma; Mutation, Missense; Neoplasm Metastasis; Prognosis; Proto-Oncogene Proteins B-raf; Selection, Genetic; Skin Neoplasms; Treatment Outcome; Valine

2011
BRAFV600E mutation, TIMP-1 upregulation, and NF-κB activation: closing the loop on the papillary thyroid cancer trilogy.
    Endocrine-related cancer, 2011, Volume: 18, Issue:6

    Topics: Adult; Amino Acid Substitution; Carcinoma; Carcinoma, Papillary; Cell Transformation, Neoplastic; Disease Progression; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Glutamic Acid; Humans; Male; Middle Aged; Mutation, Missense; Neoplasm Invasiveness; NF-kappa B; Proto-Oncogene Proteins B-raf; Signal Transduction; Thyroid Cancer, Papillary; Thyroid Neoplasms; Tissue Inhibitor of Metalloproteinase-1; Tumor Cells, Cultured; Up-Regulation; Valine

2011
Protease-sensitive conformers in broad spectrum of distinct PrPSc structures in sporadic Creutzfeldt-Jakob disease are indicator of progression rate.
    PLoS pathogens, 2011, Volume: 7, Issue:9

    Topics: Aged; Aged, 80 and over; Brain; Codon; Creutzfeldt-Jakob Syndrome; Disease Progression; Epitopes; Female; Homozygote; Humans; Male; Methionine; Middle Aged; Nonlinear Dynamics; Peptide Hydrolases; Phenotype; Prion Proteins; Prions; PrPSc Proteins; Regression Analysis; Valine

2011
Angiotensin receptor blockade attenuates glomerulosclerosis progression by promoting VEGF expression and bone marrow-derived cells recruitment.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2012, Volume: 27, Issue:7

    Topics: Angiotensin Receptor Antagonists; Animals; Blotting, Western; Bone Marrow; Bone Marrow Transplantation; Disease Progression; Female; Fluorescent Antibody Technique; Glomerulosclerosis, Focal Segmental; Green Fluorescent Proteins; Immunoenzyme Techniques; Isoantibodies; Kidney Glomerulus; Male; Nephrectomy; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Receptors, Angiotensin; Tetrazoles; Thy-1 Antigens; Valine; Valsartan; Vascular Endothelial Growth Factor A

2012
Polymorphisms of the BDNF gene show neither association with multiple sclerosis susceptibility nor clinical course.
    Journal of neuroimmunology, 2012, Volume: 244, Issue:1-2

    Topics: Adult; Age of Onset; Brain-Derived Neurotrophic Factor; Disease Progression; Female; Genetic Association Studies; Genetic Predisposition to Disease; Humans; Male; Methionine; Multiple Sclerosis; Norway; Polymorphism, Genetic; Valine

2012
Aliskiren improves left ventricular dysfunction and reduces cardiac dilation in Syrian cardiomyopathic hamsters.
    Journal of cardiovascular pharmacology, 2012, Volume: 59, Issue:6

    Topics: Amides; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Cardiomyopathy, Dilated; Cricetinae; Disease Models, Animal; Disease Progression; Drug Therapy, Combination; Fumarates; Male; Renin; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan; Ventricular Dysfunction, Left

2012
Deletion of the angiotensin II type 1a receptor prevents atherosclerotic plaque rupture in apolipoprotein E-/- mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2012, Volume: 32, Issue:6

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Apolipoproteins E; Atherosclerosis; Carotid Artery Diseases; Carotid Artery, Common; CD36 Antigens; Disease Models, Animal; Disease Progression; Focal Adhesion Kinase 1; Gene Deletion; JNK Mitogen-Activated Protein Kinases; Lipids; Lipoproteins, LDL; Macrophages; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Plaque, Atherosclerotic; Receptor, Angiotensin, Type 1; Rupture, Spontaneous; Superoxides; Tetrazoles; Time Factors; Valine; Valsartan

2012
Effect of valsartan on the pathological progression of hepatic fibrosis in rats with type 2 diabetes.
    European journal of pharmacology, 2012, Jun-15, Volume: 685, Issue:1-3

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Apoptosis; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Progression; Fatty Liver; Gene Expression Regulation; Hepatocytes; In Situ Nick-End Labeling; Liver Cirrhosis, Experimental; Mitochondria, Liver; Non-alcoholic Fatty Liver Disease; Rats; Rats, Sprague-Dawley; Tetrazoles; Valine; Valsartan

2012
Varicella zoster virus vasculopathy: a treatable form of rapidly progressive multi-infarct dementia after 2 years' duration.
    Journal of the neurological sciences, 2012, Dec-15, Volume: 323, Issue:1-2

    Topics: Acyclovir; Aged; Antiviral Agents; Apraxias; Basal Ganglia Cerebrovascular Disease; Cyclophosphamide; Dementia, Multi-Infarct; Disease Progression; Drug Therapy, Combination; Dysarthria; Encephalitis, Varicella Zoster; Gait Disorders, Neurologic; Humans; Magnetic Resonance Angiography; Male; Memory Disorders; Prednisone; Pupil Disorders; Recovery of Function; Thalamus; Valacyclovir; Valine; Vertebrobasilar Insufficiency; Vision Disorders

2012
Progressive outer retinal necrosis presenting as cherry red spot.
    Ocular immunology and inflammation, 2012, Volume: 20, Issue:5

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; AIDS-Related Opportunistic Infections; Antiretroviral Therapy, Highly Active; Antiviral Agents; Blindness; Disease Progression; Eye Infections, Viral; Female; Herpes Zoster Ophthalmicus; Humans; Middle Aged; Mucolipidoses; Retinal Necrosis Syndrome, Acute; Valacyclovir; Valine

2012
Additive effects of cilnidipine and angiotensin II receptor blocker in preventing the progression of diabetic nephropathy in diabetic spontaneously hypertensive rats.
    Clinical and experimental nephrology, 2013, Volume: 17, Issue:1

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Biomarkers; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dihydropyridines; Disease Progression; Drug Therapy, Combination; Glomerulonephritis; Glucagon; Glucose Transporter Type 1; Glycated Hemoglobin; Glycogen; Hypertension; Kidney; Male; Norepinephrine; Proteinuria; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Tetrazoles; Transforming Growth Factor beta1; Valine; Valsartan

2013
Infantile neuroaxonal dystrophy: a rare cause of early childhood ataxia with poor prognosis.
    Klinische Padiatrie, 2013, Volume: 225, Issue:1

    Topics: Atrophy; Base Pairing; Cerebellum; Child, Preschool; Chromosome Deletion; Diagnosis, Differential; Disease Progression; DNA Mutational Analysis; Exons; Frontal Lobe; Gait Ataxia; Group VI Phospholipases A2; Homozygote; Humans; Magnetic Resonance Imaging; Male; Neuroaxonal Dystrophies; Temporal Lobe; Valine

2013
Branched chain amino acid profile in early chronic kidney disease.
    Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 2012, Volume: 23, Issue:6

    Topics: Adult; Amino Acids, Branched-Chain; Biomarkers; C-Reactive Protein; Case-Control Studies; Disease Progression; Humans; Hypoalbuminemia; India; Inflammation Mediators; Leucine; Malnutrition; Middle Aged; Nutritional Status; Renal Insufficiency, Chronic; Serum Albumin; Valine

2012
Plasma sphingolipids are biomarkers of metabolic syndrome in non-human primates maintained on a Western-style diet.
    International journal of obesity (2005), 2013, Volume: 37, Issue:8

    Topics: Animals; Biomarkers; Ceramides; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Disease Progression; Fructose; Insulin Resistance; Macaca mulatta; Male; Metabolic Syndrome; Obesity; Risk Factors; Serine C-Palmitoyltransferase; Sphingolipids; Valine

2013
Effect of angiotensin II antagonism on the regression of kidney disease in the rat.
    Kidney international, 2002, Volume: 62, Issue:3

    Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Body Weight; Collagen Type III; Disease Progression; Kidney Diseases; Kidney Glomerulus; Lisinopril; Macrophages; Male; Monocytes; Proteinuria; Rats; Rats, Wistar; Renal Circulation; Tetrazoles; Valine; Valsartan

2002
Tissue angiotensin II during progression or ventricular hypertrophy to heart failure in hypertensive rats; differential effects on PKC epsilon and PKC beta.
    Journal of molecular and cellular cardiology, 2002, Volume: 34, Issue:10

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Disease Progression; Echocardiography; Enzyme Activation; Heart Failure; Hypertension; Male; Myocardium; Organ Size; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-epsilon; Protein Transport; Rats; Rats, Inbred Dahl; Stress, Mechanical; Tetrazoles; Valine; Valsartan; Ventricular Function, Left

2002
Probable sporadic Creutzfeldt-Jakob disease with valine homozygosity at codon 129 and bilateral middle cerebellar peduncle lesions.
    Internal medicine (Tokyo, Japan), 2003, Volume: 42, Issue:2

    Topics: Aged; Cerebellar Ataxia; Codon; Creutzfeldt-Jakob Syndrome; Disease Progression; Electroencephalography; Fatal Outcome; Heterozygote; Humans; Magnetic Resonance Imaging; Male; Polymorphism, Genetic; Severity of Illness Index; Valine

2003
CD24 is a genetic modifier for risk and progression of multiple sclerosis.
    Proceedings of the National Academy of Sciences of the United States of America, 2003, Dec-09, Volume: 100, Issue:25

    Topics: Alanine; Alleles; Animals; Antigens, CD; CD24 Antigen; CD3 Complex; Cell Membrane; Cloning, Molecular; Disease Progression; DNA, Complementary; Dose-Response Relationship, Drug; Encephalomyelitis, Autoimmune, Experimental; Flow Cytometry; Genetic Predisposition to Disease; Genotype; Humans; Membrane Glycoproteins; Mice; Models, Genetic; Multiple Sclerosis; Open Reading Frames; Pedigree; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Risk Factors; Time Factors; Transfection; Valine

2003
Aldosterone levels after angiotensin receptor blocker treatment.
    Circulation, 2004, Apr-13, Volume: 109, Issue:14

    Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Disease Progression; Heart Failure; Humans; Tetrazoles; Valine; Valsartan

2004
Reduced reactivation rate in mutant CuZnSOD and progression rate of amyotrophic lateral sclerosis.
    European journal of neurology, 2004, Volume: 11, Issue:6

    Topics: Alanine; Amyotrophic Lateral Sclerosis; Bacteria; Blotting, Western; Cloning, Molecular; Copper; Disease Progression; Gene Expression; Glycine; Humans; Isoenzymes; Mutagenesis, Site-Directed; Mutation; Recombinant Proteins; Sequence Analysis, Protein; Superoxide Dismutase; Temperature; Time Factors; Valine; Zinc

2004
Negative association between catechol-O-methyltransferase (COMT) gene Val158Met polymorphism and persistent tardive dyskinesia in schizophrenia.
    Journal of neural transmission (Vienna, Austria : 1996), 2005, Volume: 112, Issue:8

    Topics: Adult; Amino Acid Substitution; Antipsychotic Agents; Brain Chemistry; Catechol O-Methyltransferase; Cohort Studies; Disease Progression; DNA Mutational Analysis; Drug Administration Schedule; Dyskinesia, Drug-Induced; Female; Genetic Markers; Genetic Predisposition to Disease; Genetic Testing; Genotype; Humans; Male; Methionine; Middle Aged; Polymorphism, Genetic; Schizophrenia; Valine

2005
Her2 genotype and breast cancer progression in Korean women.
    Pathology international, 2005, Volume: 55, Issue:2

    Topics: Adult; Aged; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Intraductal, Noninfiltrating; Disease Progression; Female; Genes, erbB-2; Genetic Predisposition to Disease; Genotype; Humans; Immunohistochemistry; Korea; Middle Aged; Odds Ratio; Oncogene Proteins v-erbB; Polymorphism, Genetic; Proto-Oncogene Mas; Risk Factors; Valine

2005
Investigation of the effect of brain-derived neurotrophic factor (BDNF) polymorphisms on the risk of late-onset Alzheimer's disease (AD) and quantitative measures of AD progression.
    Neuroscience letters, 2005, May-13, Volume: 379, Issue:3

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Black People; Brain-Derived Neurotrophic Factor; Case-Control Studies; Disease Progression; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Male; Methionine; Polymorphism, Genetic; Risk; Valine; White People

2005
The 5alpha-reductase type II A49T and V89L high-activity allelic variants are more common in men with prostate cancer compared with the general population.
    European urology, 2005, Volume: 48, Issue:4

    Topics: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Aged; Alanine; Alleles; Arginine; Biomarkers, Tumor; Case-Control Studies; Dihydrotestosterone; Disease Progression; Follow-Up Studies; Genetic Predisposition to Disease; Genotype; Glutamine; Humans; Leucine; Luteinizing Hormone; Male; Middle Aged; Point Mutation; Polymorphism, Genetic; Prostatic Hyperplasia; Prostatic Neoplasms; Receptors, Androgen; Risk Factors; Sex Hormone-Binding Globulin; Sweden; Terminal Repeat Sequences; Testosterone; Threonine; Valine

2005
The Val158Met polymorphism of the catechol-O-methyltransferase gene is associated with the PSA-progression-free survival in prostate cancer patients treated with estramustine phosphate.
    European urology, 2005, Volume: 48, Issue:5

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Catechol O-Methyltransferase; Disease Progression; Disease-Free Survival; Estramustine; Genetic Predisposition to Disease; Genotype; Humans; Male; Methionine; Middle Aged; Polymorphism, Genetic; Prodrugs; Prostate-Specific Antigen; Prostatic Neoplasms; Valine

2005
Prediction of progression to cirrhosis by a glutathione S-transferase P1 polymorphism in subjects with hereditary hemochromatosis.
    Archives of internal medicine, 2005, Sep-12, Volume: 165, Issue:16

    Topics: Adult; Aged; Aged, 80 and over; Alanine; Disease Progression; Female; Genotype; Glutathione Transferase; Hemochromatosis; Hepatitis C, Chronic; Humans; Isoleucine; Liver Cirrhosis; Logistic Models; Male; Middle Aged; Oxidative Stress; Polymorphism, Genetic; Prognosis; Valine

2005
FMS receptor for M-CSF (CSF-1) is sensitive to the kinase inhibitor imatinib and mutation of Asp-802 to Val confers resistance.
    Oncogene, 2006, Jan-05, Volume: 25, Issue:1

    Topics: Animals; Antineoplastic Agents; Aspartic Acid; Benzamides; Disease Progression; Dose-Response Relationship, Drug; Down-Regulation; Drug Resistance, Neoplasm; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Inflammation; Inhibitory Concentration 50; Macrophage Colony-Stimulating Factor; Mice; Mutation; Neoplasms; Oncogene Protein v-cbl; Phosphorylation; Piperazines; Protein Structure, Tertiary; Proto-Oncogene Proteins c-crk; Proto-Oncogene Proteins c-kit; Pyrimidines; Rats; Receptor Protein-Tyrosine Kinases; Receptor, Macrophage Colony-Stimulating Factor; Signal Transduction; Time Factors; Valine

2006
Angiotensin II receptor antagonists and heart failure: angiotensin-converting-enzyme inhibitors remain the first-line option.
    Prescrire international, 2005, Volume: 14, Issue:79

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Captopril; Clinical Trials as Topic; Disease Progression; Drug Therapy, Combination; Heart Failure; Humans; Hypokalemia; Hypotension; Losartan; Meta-Analysis as Topic; Myocardial Infarction; Renal Insufficiency; Tetrazoles; Valine

2005
Functional polymorphism 57Val>Ile of aurora kinase A associated with increased risk of gastric cancer progression.
    Cancer letters, 2006, Oct-28, Volume: 242, Issue:2

    Topics: Alleles; Aurora Kinase A; Aurora Kinases; Case-Control Studies; Disease Progression; Genetic Predisposition to Disease; Genotype; Haplotypes; Humans; Isoleucine; Odds Ratio; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Protein Serine-Threonine Kinases; Risk; Stomach Neoplasms; Valine

2006
Incremental prognostic value of changes in B-type natriuretic peptide in heart failure.
    The American journal of medicine, 2006, Volume: 119, Issue:1

    Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Biomarkers; Disease Progression; Echocardiography; Heart Failure; Heart Ventricles; Humans; Middle Aged; Natriuretic Peptide, Brain; Prognosis; Proportional Hazards Models; Randomized Controlled Trials as Topic; Stroke Volume; Survival Rate; Tetrazoles; Valine; Valsartan

2006
Combined AGE inhibition and ACEi decreases the progression of established diabetic nephropathy in B6 db/db mice.
    Kidney international, 2006, Volume: 70, Issue:3

    Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzazepines; Collagen Type IV; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Progression; Drug Therapy, Combination; Enalapril; Female; Glycation End Products, Advanced; Mice; Mice, Inbred C57BL; Mice, Obese; Pyridoxamine; Tetrazoles; Valine; Valsartan; Vitamin B Complex

2006
Valsartan inhibited the accumulation of dendritic cells in rat fibrotic renal tissue.
    Cellular & molecular immunology, 2006, Volume: 3, Issue:3

    Topics: Angiotensin II Type 2 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Dendritic Cells; Disease Models, Animal; Disease Progression; Fibrosis; Immunohistochemistry; Kidney Diseases; Kidney Function Tests; Kidney Tubules; Membrane Glycoproteins; Proteinuria; Rats; Rats, Sprague-Dawley; Tetrazoles; Valine; Valsartan

2006
Tumor-derived fibronectin is involved in melanoma cell invasion and regulated by V600E B-Raf signaling pathway.
    The Journal of investigative dermatology, 2007, Volume: 127, Issue:2

    Topics: Cells, Cultured; Disease Progression; Early Growth Response Protein 1; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Fibronectins; Glutamic Acid; Humans; Melanocytes; Melanoma; Mutation; Neoplasm Invasiveness; Proto-Oncogene Proteins B-raf; Signal Transduction; Valine

2007
Local delivery of angiotensin receptor blocker into the kidney ameliorates progression of experimental glomerulonephritis.
    Kidney international, 2006, Volume: 70, Issue:9

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Disease Progression; Drug Implants; Female; Gene Expression Regulation; Glomerulonephritis; Isoantibodies; Kidney Glomerulus; Microcirculation; Nephrectomy; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; RNA, Messenger; Tetrazoles; Valine; Valsartan; Vasoconstrictor Agents

2006
Telmisartan, an angiotensin II type 1 receptor blocker, controls progress of nonalcoholic steatohepatitis in rats.
    Digestive diseases and sciences, 2007, Volume: 52, Issue:12

    Topics: Actins; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Biomarkers; Blotting, Western; Collagen Type I; Disease Models, Animal; Disease Progression; Fatty Liver; Hypoglycemic Agents; Immunohistochemistry; Male; Pioglitazone; PPAR gamma; Rats; Rats, Inbred F344; Spectrophotometry; Telmisartan; Tetrazoles; Thiazolidinediones; Treatment Outcome; Valine; Valsartan

2007
Herpes treatment may limit HIV transmission and progression.
    The Lancet. Infectious diseases, 2007, Volume: 7, Issue:4

    Topics: Acyclovir; Antiviral Agents; Disease Progression; Disease Transmission, Infectious; Female; Genitalia, Female; Herpes Simplex; HIV Infections; HIV-1; Humans; RNA, Viral; Time Factors; Valacyclovir; Valine; Viral Load

2007
BRAF V600E mutation in anaplastic thyroid carcinomas and their accompanying differentiated carcinomas.
    British journal of cancer, 2007, May-21, Volume: 96, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Base Sequence; Carcinoma; Disease Progression; DNA Mutational Analysis; Female; Gene Frequency; Glutamic Acid; Humans; Male; Middle Aged; Models, Biological; Mutation, Missense; Proto-Oncogene Proteins B-raf; Thyroid Neoplasms; Valine

2007
The V118I mutation as a marker of advanced HIV infection and disease progression.
    Antiviral therapy, 2007, Volume: 12, Issue:2

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; Cross-Sectional Studies; Disease Progression; Drug Resistance, Multiple, Viral; Female; Follow-Up Studies; Genotype; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Isoleucine; Logistic Models; Male; Mutation; Prognosis; Proportional Hazards Models; Reverse Transcriptase Inhibitors; Risk Assessment; RNA, Viral; Severity of Illness Index; Time Factors; Treatment Failure; Valine

2007
Akt3 and mutant V600E B-Raf cooperate to promote early melanoma development.
    Cancer research, 2008, May-01, Volume: 68, Issue:9

    Topics: Animals; Cell Adhesion; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Chromones; Disease Progression; Glutamic Acid; Humans; MAP Kinase Signaling System; Melanocytes; Melanoma; Mice; Morpholines; Mutant Proteins; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-akt; Signal Transduction; Valine

2008
Role of CCR2 genotype in the clinical course of syncytium-inducing (SI) or non-SI human immunodeficiency virus type 1 infection and in the time to conversion to SI virus variants.
    The Journal of infectious diseases, 1998, Volume: 178, Issue:6

    Topics: Cells, Cultured; Confidence Intervals; Disease Progression; Genetic Variation; Genotype; Giant Cells; HIV Seropositivity; HIV-1; Homosexuality, Male; Humans; Isoleucine; Leukocytes, Mononuclear; Male; Point Mutation; Proportional Hazards Models; Receptors, CCR2; Receptors, CCR5; Receptors, Chemokine; Receptors, Cytokine; Time Factors; Valine

1998
Effects of AT1-receptor blockade on progression of left ventricular dysfunction in dogs with heart failure.
    The American journal of physiology, 1999, Volume: 276, Issue:4

    Topics: Angiotensin Receptor Antagonists; Animals; Cardiac Output, Low; Disease Progression; Dogs; Dose-Response Relationship, Drug; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles; Valine; Valsartan; Ventricular Dysfunction, Left; Ventricular Remodeling

1999
Chemokine control of HIV-1 infection.
    Nature, 1999, Aug-19, Volume: 400, Issue:6746

    Topics: Acquired Immunodeficiency Syndrome; Cell Line; Chemokine CCL2; Chemokine CXCL12; Chemokines, CXC; Dimerization; Disease Progression; HIV Infections; HIV-1; Humans; Isoleucine; Point Mutation; Receptors, CCR2; Receptors, CCR5; Receptors, Chemokine; Receptors, CXCR4; Receptors, Cytokine; Valine

1999
H-ras gene mutations in salivary gland mucoepidermoid carcinomas.
    Cancer, 2000, Feb-01, Volume: 88, Issue:3

    Topics: Adenine; Adolescent; Adult; Aged; Aged, 80 and over; Aspartic Acid; Carcinoma, Mucoepidermoid; Child; Codon; Disease Progression; Female; Gene Expression Regulation; Gene Frequency; Genes, ras; Guanine; Humans; Incidence; Male; Middle Aged; Point Mutation; Salivary Gland Neoplasms; Thymine; Valine

2000
V89L polymorphism of type-2, 5-alpha reductase enzyme gene predicts prostate cancer presence and progression.
    Urology, 2001, Volume: 57, Issue:1

    Topics: Aged; Alleles; Cholestenone 5 alpha-Reductase; Disease Progression; Follow-Up Studies; Genetic Markers; Humans; Leucine; Male; Middle Aged; Neoplasm Proteins; Neoplasm Recurrence, Local; Odds Ratio; Oxidoreductases; Phenotype; Polymorphism, Genetic; Prostatic Neoplasms; Valine

2001
Basic Science.
    Urology, 2001, Volume: 57, Issue:1

    Topics: Cholestenone 5 alpha-Reductase; Disease Progression; Genotype; Humans; Leucine; Male; Neoplasm Proteins; Neoplasm Recurrence, Local; Oxidoreductases; Polymorphism, Genetic; Prostate-Specific Antigen; Valine

2001
Renoprotective and anti-hypertensive effects of combined valsartan and perindopril in progressive diabetic nephropathy in the transgenic (mRen-2)27 rat.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2001, Volume: 16, Issue:7

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Progression; Drug Therapy, Combination; Female; Heterozygote; Kidney; Perindopril; Rats; Renin; Tetrazoles; Valine; Valsartan

2001
Podocyte foot process broadening in experimental diabetic nephropathy: amelioration with renin-angiotensin blockade.
    Diabetologia, 2001, Volume: 44, Issue:7

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Basement Membrane; Blood Pressure; Diabetes Mellitus, Experimental; Disease Models, Animal; Disease Progression; Humans; Kidney; Kidney Glomerulus; Male; Organ Size; Ramipril; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan

2001
Recurrent myelitis associated with herpes simplex virus type 2.
    European neurology, 2001, Volume: 46, Issue:4

    Topics: Acyclovir; Aged; Disease Progression; Drug Therapy, Combination; Female; Herpes Genitalis; Herpesvirus 2, Human; Humans; Magnetic Resonance Imaging; Myelitis; Neurologic Examination; Prednisone; Recurrence; Spinal Cord; Valacyclovir; Valine

2001