Compounds > valine

valine and Cognition Disorders

valine has been researched along with Cognition Disorders in 53 studies

Research

Studies (53)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's22 (41.51)29.6817
2010's31 (58.49)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Beniwal, RP; Bhatia, T; Chen, K; Deshpande, SN; Dickerson, F; Gur, RC; Gur, RE; Iyengar, S; Narayanan, SS; Nimgaonkar, VL; Prasad, KM; Wood, J; Yolken, RH1
Alves, C; Cardoso, M; Cavaco, S; Coelho, T; Fernandes, J; Kelly, JW; Martins da Silva, A; Monteiro, C; Samões, R1
Abushakra, S; Hey, JA; Hort, J; Kocis, P; Power, A; Tolar, M; Vyhnálek, M; Yu, JY1
Elliott, E; Gil-Henn, H; Polis, B; Samson, AO; Srikanth, KD1
Ames, D; Bourgeat, P; Bush, AI; Darby, D; Ellis, KA; Harrington, KD; Laws, SM; Lim, YY; Martins, RN; Maruff, P; Masters, CL; Nathan, PJ; Pietrzak, RH; Rowe, CC; Salvado, O; Snyder, PJ; Villemagne, VL1
Baran, B; Büyükgök, D; Direskeneli, GS; Ertekin, BA; Ertekin, E; Gürvit, H; Kalem, ŞA; Özata, B; Öztürk, N; Tükel, R1
Aas, M; Agartz, I; Andreassen, OA; Athanasiu, L; Bergmann, Ø; Djurovic, S; Haukvik, UK; Hellvin, T; Lorentzen, S; Melle, I; Steen, NE; Sundet, K; Tesli, MS1
Eum, KD; Hersh, CP; Hu, H; Kelsey, K; Schwartz, J; Sparrow, D; Spiro, A; Wang, FT; Weisskopf, MG; Wright, RO1
Alosco, ML; Cohen, RA; Gunstad, J; McGeary, JE; Miller, LA; Poppas, A; Szabo, AJ1
Doja, A; Humphreys, P; McMillan, HJ; Venkateswaran, S1
Björefeldt, A; Blomgren, K; Carlström, KE; Daborg, J; Ekdahl, CT; Hanse, E; Kalm, M; Pekna, M; Perez-Alcazar, M; Stokowska, A; Wasling, P; Zetterberg, H1
Feng, GF; Han, H; Hu, XD; Liu, Y; Qian, YH; Shi, LL; Yang, WN1
Cao, A; Chen, S; Chen, X; Guo, L; Ji, W; Ju, K; Li, N; Xu, P; Yang, C; Zheng, H1
Alfimova, MV; Gabaeva, MV; Golimbet, VE; Korovaitseva, GI; Lezheiko, TV; Oleichik, IV; Stolyarov, SA1
Ahlm, C; Aksamit, A; Aoki, F; Aurelius, E; Cloud, G; Cruz-Flores, S; Dale, I; Eriksson, BM; Gnann, JW; Griffiths, P; Hanfelt-Goade, D; Hanley, D; Hart, J; Hinthorn, D; Jackson, AC; Jester, P; Miedzinski, L; Schliamser, S; Sköldenberg, B; Studahl, M; Whitley, RJ1
Barber, J; Burchard, EG; Burke, JF; Diaz-Arrastia, R; Eng, C; Ferguson, AR; Gardner, RC; Hu, D; Lingsma, HF; Manley, GT; McAllister, TW; Mukherjee, P; Oh, SS; Okonkwo, DO; Puccio, AM; Rosand, J; Satris, GG; Sharma, S; Sorani, MD; Tarapore, PE; Temkin, NR; Valadka, AB; Wang, KK; Winkler, EA; Yue, JK; Yuh, EL1
Ballard, D; Bannerman, DM; Barkus, C; Chen, J; Harrison, PJ; Korn, C; Laatikainen, LM; Lee, S; Sharp, T; Stumpenhorst, K; Tunbridge, EM; Weinberger, DR1
Devoto, M; Emanuel, BS; Franconi, CP; Gur, RE; McDonald-McGinn, D; McNamara, MA; Moss, E; Salmons, H; Zackai, EH1
Feng, S; Gan, R; Gao, L; Nie, K; Tang, H; Wang, L; Zhang, Y; Zhao, J; Zhao, X; Zhu, R1
Feng, X; Jia, J; Wang, W; Xie, Y; Zhang, G1
Cens, T; Charnet, P; Leyris, JP1
Bellingham, J; Goto, Y; Grace, AA; Grizenko, N; Joober, R; Polotskaia, A; Schmitz, N; Schwartz, G; Sengupta, S; Stepanian, MT1
Schmidt, L; Simon, TJ; Takarae, Y; Tassone, F1
Cortez, MA; Eubanks, JH; Han, H; Leschenko, Y; Perez Velazquez, JL; Snead, OC; Stewart, LS; Wu, Y1
Bae, KY; Kim, JM; Kim, SW; Park, KH; Shin, IS; Stewart, R; Yang, SJ; Yoon, JS1
Kiess, W; Klammt, J; Kratzsch, J; Kruis, T; Müller, E; Pfäffle, R; Schlicke, M; Schmidt, G; van de Leur, HS; Wallborn, T; Wüller, S1
Ferrell, R; Fiocco, AJ; Harris, TB; Li, R; Lindquist, K; Nalls, M; Simonsick, EM; Yaffe, K1
Berry, MN; Howard, TD; Kaczorowski, J; Keshavan, MS; Kwapil, TR; Schoch, K; Shashi, V; Spence, EJ1
Agartz, I; Andreassen, OA; Athanasiu, L; Djurovic, S; Mattingsdal, M; Melle, I; Sundet, K; Wirgenes, KV1
Fan, M; Jiang, T; Liu, B; Song, M; Wang, Z; Xu, C; Zhen, X1
Adamson, M; Kennedy, Q; Murphy, GM; Noda, A; Taylor, JL; Yesavage, JA; Zeitzer, JM1
Almkvist, O; Bogdanovic, N; Långström, B; Nordberg, A; Schöll, M; Viitanen, M; Wall, A1
Ehmann, TS; Honer, WG; Kennedy, JL; Kopala, LC; Lang, DJ; Macewan, GW; Shiau, G; Smith, GN; Tee, K; Thornton, AE; Voineskos, AN1
Simon, TJ; Stoddard, J; Takarae, Y1
Eack, SM; Iyengar, S; Keshavan, MS; Nimgaonkar, VL; Prasad, KM; Yolken, RH1
Bresolin, N; Castelli, E; Comi, GP; Crimi, M; Del Bo, R; Giorda, R; Locatelli, F; Martinelli-Boneschi, F; Pozzoli, U; Scarlato, G1
Hong, CJ; Lai, IC; Liao, DL; Liou, YJ; Tsai, SJ1
Hori, K; Kobayashi, M; Masaki, T; Masuo, Y; Miyamoto, M; Noguchi, H; Nomura, M; Takamatsu, K; Tsubokawa, H1
Baker, K; Baldeweg, T; Scambler, P; Sivagnanasundaram, S; Skuse, D1
Cassano, P; Del Zompo, M; Galderisi, S; Invernizzi, G; Kirkpatrick, B; Maj, M; Mucci, A; Piccardi, P; Pini, S; Rossi, A; Severino, G; Stratta, P; Vita, A1
Borkowska, A; Czerski, PM; Hauser, J; Kapelski, P; Leszczynska-Rodziewicz, A; Rybakowski, JK; Skibinska, M; Szczepankiewicz, A1
Antonarakis, SE; Dahoun, SP; Debbane, M; Eliez, S; Glaser, B; Hinard, C; Morris, MA1
Bilbao, JR; Castaño, L; Echevarria, E; Galdos, P; Isusi, P; Krabbendam, L; Martin-Pagola, A; Papiol, S; Van Os, J1
Andreasen, NC; Ho, BC; Librant, A; Milev, P; O'Leary, DS; Wassink, TH1
Arranz, MJ; Lopez-Ilundain, JM; Mata, I; Murray, RM; Staddon, S; Tabares-Seisdedos, R1
Jayathilake, K; Meltzer, HY; Woodward, ND1
Anselmetti, S; Bechi, M; Bosia, M; Cavallaro, R; Cocchi, F; Marino, E; Poletti, S; Smeraldi, E1
Daly, E; De Haan, L; Figee, M; Glaser, B; Linszen, DH; Morris, R; Murphy, DG; Murphy, KC; Owen, MJ; van Amelsvoort, T; Zinkstok, J1
Horan, M; Jackson, A; Mayes, A; Miyajima, F; Ollier, W; Payton, A; Pendleton, N; Rabbitt, P; Thacker, N1
Andreasen, NC; Dawson, JD; Ho, BC; Wassink, TH1
Hong, CJ; Hsieh, CH; Liou, YJ; Liu, ME; Tsai, SJ; Tsai, YL1
Carrasco-Marin, E; Crespo-Facorro, B; Gonzalez-Blanch, C; Mata, I; Pelayo-Teran, JM; Perez-Iglesias, R; Rodríguez-Sanchez, JM; Vazquez-Barquero, JL1
Bai, F; Deng, LL; Qian, Y; Shi, YM; Yu, H; Yuan, YG; Zhang, ZJ1

Trials

6 trial(s) available for valine and Cognition Disorders

ArticleYear
Discovery and Identification of an Endogenous Metabolite of Tramiprosate and Its Prodrug ALZ-801 that Inhibits Beta Amyloid Oligomer Formation in the Human Brain.
    CNS drugs, 2018, Volume: 32, Issue:9

    Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Chromatography, Liquid; Cognition Disorders; Computer Simulation; Drug Administration Routes; Female; Humans; Male; Mental Status Schedule; Middle Aged; Models, Chemical; Nonlinear Dynamics; Peptide Fragments; Prodrugs; Propionates; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Taurine; Valine

2018
Herpes Simplex Encephalitis: Lack of Clinical Benefit of Long-term Valacyclovir Therapy.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2015, Sep-01, Volume: 61, Issue:5

    Topics: Acyclovir; Adolescent; Adult; Aged; Aged, 80 and over; Antiviral Agents; Cognition Disorders; Encephalitis, Herpes Simplex; Female; Follow-Up Studies; Humans; Male; Middle Aged; Quality of Life; Valacyclovir; Valine; Young Adult

2015
COMT Val 158 Met polymorphism is associated with nonverbal cognition following mild traumatic brain injury.
    Neurogenetics, 2016, Volume: 17, Issue:1

    Topics: Adult; Amino Acid Substitution; Brain Injuries; Catechol O-Methyltransferase; Cognition; Cognition Disorders; Female; Genetic Association Studies; Humans; Male; Methionine; Middle Aged; Mutation, Missense; Neuropsychological Tests; Pilot Projects; Polymorphism, Single Nucleotide; Valine

2016
COMT Val108/158Met polymorphism and the modulation of task-oriented behavior in children with ADHD.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2008, Volume: 33, Issue:13

    Topics: Amino Acid Substitution; Attention Deficit Disorder with Hyperactivity; Catechol O-Methyltransferase; Central Nervous System Stimulants; Child; Cognition Disorders; Cross-Over Studies; DNA Mutational Analysis; Double-Blind Method; Female; Genetic Predisposition to Disease; Genetic Testing; Genotype; Humans; Male; Mental Processes; Methionine; Methylphenidate; Placebo Effect; Polymorphism, Genetic; Thinking; Valine

2008
Antiherpes virus-specific treatment and cognition in schizophrenia: a test-of-concept randomized double-blind placebo-controlled trial.
    Schizophrenia bulletin, 2013, Volume: 39, Issue:4

    Topics: Acyclovir; Adolescent; Adult; Antipsychotic Agents; Antiviral Agents; Cognition Disorders; Double-Blind Method; Drug Therapy, Combination; Female; Herpes Simplex; Herpesvirus 1, Human; Humans; Learning; Male; Memory, Short-Term; Middle Aged; Neuropsychological Tests; Psychotic Disorders; Schizophrenia; Valacyclovir; Valine; Young Adult

2013
Lack of influence of COMT Val158Met genotype on cognition in first-episode non-affective psychosis.
    Schizophrenia research, 2008, Volume: 102, Issue:1-3

    Topics: Adult; Antipsychotic Agents; Catechol O-Methyltransferase; Cognition Disorders; Diagnostic and Statistical Manual of Mental Disorders; Female; Genetic Predisposition to Disease; Genotype; Humans; Longitudinal Studies; Male; Methionine; Neuropsychological Tests; Phenotype; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Psychiatric Status Rating Scales; Psychotic Disorders; Schizophrenia; Schizophrenic Psychology; Valine

2008

Other Studies

47 other study(ies) available for valine and Cognition Disorders

ArticleYear
Emotion discrimination in humans: Its association with HSV-1 infection and its improvement with antiviral treatment.
    Schizophrenia research, 2018, Volume: 193

    Topics: Acyclovir; Adolescent; Adult; Antipsychotic Agents; Antiviral Agents; Cognition Disorders; Emotions; Female; Follow-Up Studies; Herpes Simplex; Humans; Male; Middle Aged; Neuropsychological Tests; Randomized Controlled Trials as Topic; Severity of Illness Index; Valacyclovir; Valine; Young Adult

2018
Age-dependent cognitive dysfunction in untreated hereditary transthyretin amyloidosis.
    Journal of neurology, 2018, Volume: 265, Issue:2

    Topics: Adult; Age of Onset; Aging; Amyloid Neuropathies, Familial; Anxiety; Chi-Square Distribution; Cognition Disorders; Depression; Female; Humans; Male; Methionine; Middle Aged; Mutation; Neurologic Examination; Neuropsychological Tests; Prealbumin; Statistics, Nonparametric; Valine

2018
L-Norvaline Reverses Cognitive Decline and Synaptic Loss in a Murine Model of Alzheimer's Disease.
    Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2018, Volume: 15, Issue:4

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Arginase; Calcium-Binding Proteins; Cerebral Cortex; Cognition Disorders; Dendritic Spines; Hippocampus; Male; Maze Learning; Mice; Mice, Transgenic; Microfilament Proteins; Microglia; Mutation; Neurons; Presenilin-1; tau Proteins; Valine

2018
BDNF Val66Met, Aβ amyloid, and cognitive decline in preclinical Alzheimer's disease.
    Neurobiology of aging, 2013, Volume: 34, Issue:11

    Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Aniline Compounds; Apolipoprotein E4; Australia; Brain-Derived Neurotrophic Factor; Cognition Disorders; Female; Genotype; Hippocampus; Humans; Magnetic Resonance Imaging; Male; Memory, Episodic; Methionine; Neuropsychological Tests; Positron-Emission Tomography; Psychiatric Status Rating Scales; Thiazoles; Valine

2013
COMT Val158Met polymorphism and executive functions in obsessive-compulsive disorder.
    The Journal of neuropsychiatry and clinical neurosciences, 2013,Summer, Volume: 25, Issue:3

    Topics: Adult; Analysis of Variance; Catechol O-Methyltransferase; Cognition Disorders; Executive Function; Female; Gene Frequency; Genotype; Humans; Male; Methionine; Neuropsychological Tests; Obsessive-Compulsive Disorder; Polymorphism, Single Nucleotide; Psychiatric Status Rating Scales; Valine; Young Adult

2013
BDNF val66met modulates the association between childhood trauma, cognitive and brain abnormalities in psychoses.
    Progress in neuro-psychopharmacology & biological psychiatry, 2013, Oct-01, Volume: 46

    Topics: Adolescent; Adult; Bipolar Disorder; Brain; Brain-Derived Neurotrophic Factor; Child Abuse; Cognition Disorders; Hippocampus; Humans; Lateral Ventricles; Methionine; Psychotic Disorders; Valine; Young Adult

2013
Modifying roles of glutathione S-transferase polymorphisms on the association between cumulative lead exposure and cognitive function.
    Neurotoxicology, 2013, Volume: 39

    Topics: Aged; Aged, 80 and over; Cognition Disorders; Cohort Studies; Gene-Environment Interaction; Genetic Predisposition to Disease; Genotype; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Lead; Male; Mental Status Schedule; Middle Aged; Polymorphism, Genetic; Spectrometry, X-Ray Emission; Valine; Veterans

2013
Brain-derived neurotrophic factor Val66Met polymorphism and cognitive function in persons with cardiovascular disease.
    Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society, 2013, Volume: 13, Issue:4

    Topics: Aged; Aged, 80 and over; Alleles; Attention; Brain; Brain-Derived Neurotrophic Factor; Cardiovascular Diseases; Cognition; Cognition Disorders; Female; Genetic Markers; Genetic Predisposition to Disease; Geriatric Assessment; Humans; Male; Memory; Methionine; Middle Aged; Neuropsychological Tests; Polymorphism, Genetic; Valine

2013
Adolescent onset cognitive regression and neuropsychiatric symptoms associated with the A140V MECP2 mutation.
    Developmental medicine and child neurology, 2014, Volume: 56, Issue:1

    Topics: Activities of Daily Living; Adolescent; Adolescent Development; Age of Onset; Alanine; Cognition; Cognition Disorders; Diagnosis, Differential; Electroencephalography; Female; Humans; Intellectual Disability; Learning Disabilities; Mental Retardation, X-Linked; Methyl-CpG-Binding Protein 2; Mutation, Missense; Phenotype; Severity of Illness Index; Valine

2014
Altered cognitive performance and synaptic function in the hippocampus of mice lacking C3.
    Experimental neurology, 2014, Volume: 253

    Topics: Animals; Animals, Newborn; Avoidance Learning; Cognition Disorders; Complement C3; Disease Models, Animal; Dizocilpine Maleate; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; Gene Expression Regulation; Hippocampus; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Net; Neurons; Picrotoxin; Synapses; Ultrasonography; Valine

2014
The effects of valsartan on cognitive deficits induced by aluminum trichloride and d-galactose in mice.
    Neurological research, 2014, Volume: 36, Issue:7

    Topics: Acetylcholinesterase; Aluminum Chloride; Aluminum Compounds; Animals; Cerebral Cortex; Chlorides; Cognition Disorders; Dementia; Disease Models, Animal; Galactose; Glutathione Peroxidase; Hippocampus; Malondialdehyde; Maze Learning; Memory Disorders; Mice; Nootropic Agents; Oxidative Stress; Random Allocation; Superoxide Dismutase; Tetrazoles; Valine; Valsartan

2014
Association of Catechol-O-methyltransferase val/met polymorphism with cognitive function in Gilles de la Tourette syndrome patients.
    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2015, Volume: 36, Issue:4

    Topics: Adolescent; Analysis of Variance; Catechol O-Methyltransferase; Child; Cognition Disorders; Female; Genetic Association Studies; Genotype; Humans; Interleukin 1 Receptor Antagonist Protein; Interleukin-1beta; Male; Methionine; Minisatellite Repeats; Neuropsychological Tests; Polymorphism, Genetic; Receptors, Dopamine D4; Retrospective Studies; Tourette Syndrome; Valine

2015
[No effect of the BDNF Val66Met polymorphism on cognitive deficit in patients with schizophrenia and on the risk of the disease in their relatives].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2015, Volume: 115, Issue:1

    Topics: Adult; Brain-Derived Neurotrophic Factor; Cognition Disorders; Female; Genetic Predisposition to Disease; Humans; Male; Methionine; Pedigree; Polymorphism, Genetic; Schizophrenia; Valine; Young Adult

2015
Genotype-Dependent Effects of COMT Inhibition on Cognitive Function in a Highly Specific, Novel Mouse Model of Altered COMT Activity.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2016, Volume: 41, Issue:13

    Topics: Analysis of Variance; Animals; Benzophenones; Brain; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Choice Behavior; Cognition Disorders; Disease Models, Animal; Exploratory Behavior; Genotype; Maze Learning; Methionine; Mice; Mice, Transgenic; Nitrophenols; Polymorphism, Single Nucleotide; Reaction Time; Tolcapone; Valine

2016
IQ and hemizygosity for the Val
    American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2016, Volume: 171, Issue:8

    Topics: 22q11 Deletion Syndrome; Adolescent; Catechol O-Methyltransferase; Child; Chromosome Deletion; Chromosomes, Human, Pair 22; Cognition; Cognition Disorders; Female; Genetic Association Studies; Genetic Predisposition to Disease; Hemizygote; Humans; Intelligence Tests; Male; Methionine; Polymorphism, Single Nucleotide; Valine; Young Adult

2016
Catechol-O-methyltransferase Val158Met polymorphism influences prefrontal executive function in early Parkinson's disease.
    Journal of the neurological sciences, 2016, Oct-15, Volume: 369

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Catechol O-Methyltransferase; Cognition Disorders; Executive Function; Female; Gene Frequency; Genotype; Humans; Male; Methionine; Middle Aged; Neuropsychological Tests; Parkinson Disease; Polymorphism, Genetic; Severity of Illness Index; Valine; Wechsler Scales; Young Adult

2016
Clinical characterization of an APP mutation (V717I) in five Han Chinese families with early-onset Alzheimer's disease.
    Journal of the neurological sciences, 2017, Jan-15, Volume: 372

    Topics: Age of Onset; Aged; Alzheimer Disease; Amyloid beta-Protein Precursor; Analysis of Variance; Apolipoprotein E4; Asian People; Cognition Disorders; DNA Mutational Analysis; Family Health; Female; Humans; Isoleucine; Magnetic Resonance Imaging; Male; Middle Aged; Mood Disorders; Mutation; Neuropsychological Tests; Valine

2017
Introduction into Ca(v)2.1 of the homologous mutation of Ca(v)1.2 causing the Timothy syndrome questions the role of V421 in the phenotypic definition of P-type Ca(2+) channel.
    Pflugers Archiv : European journal of physiology, 2008, Volume: 457, Issue:2

    Topics: Alanine; Animals; Arginine; Arrhythmias, Cardiac; Calcium; Calcium Channels, L-Type; Calcium Channels, N-Type; Calcium Channels, R-Type; Cation Transport Proteins; Cognition Disorders; Genotype; Glutamic Acid; Glycine; GTP-Binding Proteins; Ion Channel Gating; Kinetics; Membrane Potentials; Mutation; Phenotype; Rats; Syndrome; Valine; Xenopus

2008
Catechol-O-methyltransferase polymorphism modulates cognitive control in children with chromosome 22q11.2 deletion syndrome.
    Cognitive, affective & behavioral neuroscience, 2009, Volume: 9, Issue:1

    Topics: Adolescent; Analysis of Variance; Attention; Case-Control Studies; Catechol O-Methyltransferase; Child; Chromosome Deletion; Chromosomes, Human, Pair 22; Cognition Disorders; DiGeorge Syndrome; DNA Mutational Analysis; Female; Humans; Intelligence Tests; Male; Methionine; Neuropsychological Tests; Polymorphism, Genetic; Reaction Time; Valine

2009
Severity of atypical absence phenotype in GABAB transgenic mice is subunit specific.
    Epilepsy & behavior : E&B, 2009, Volume: 14, Issue:4

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Autoradiography; Cognition Disorders; Disease Models, Animal; Electric Stimulation; Electroencephalography; Epilepsy, Absence; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Long-Term Potentiation; Maze Learning; Mice; Mice, Transgenic; Neurons; Organophosphorus Compounds; Patch-Clamp Techniques; Phenotype; Protein Binding; Receptors, GABA-B; Tritium; Valine

2009
Role of BDNF val66met polymorphism on the association between physical activity and incident dementia.
    Neurobiology of aging, 2011, Volume: 32, Issue:3

    Topics: Activities of Daily Living; Aged; Aged, 80 and over; Brain-Derived Neurotrophic Factor; Cognition Disorders; Dementia; Female; Genome-Wide Association Study; Genotype; Humans; Incidence; Logistic Models; Male; Methionine; Motor Activity; Polymorphism, Single Nucleotide; Republic of Korea; Retrospective Studies; Statistics, Nonparametric; Valine

2011
A heterozygous mutation of the insulin-like growth factor-I receptor causes retention of the nascent protein in the endoplasmic reticulum and results in intrauterine and postnatal growth retardation.
    The Journal of clinical endocrinology and metabolism, 2010, Volume: 95, Issue:5

    Topics: Amino Acid Substitution; Birth Weight; Body Size; Cognition Disorders; Endoplasmic Reticulum; Exons; Female; Fetal Growth Retardation; Glutamic Acid; Growth Disorders; Heterozygote; Humans; Infant, Newborn; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Intellectual Disability; Microcephaly; Mutation, Missense; Polymerase Chain Reaction; Receptor, IGF Type 1; Valine

2010
COMT genotype and cognitive function: an 8-year longitudinal study in white and black elders.
    Neurology, 2010, Apr-20, Volume: 74, Issue:16

    Topics: Age Factors; Aged; Aging; Amino Acid Sequence; Amino Acid Substitution; Black People; Brain Chemistry; Catechol O-Methyltransferase; Cognition Disorders; Cytoprotection; Dementia; DNA Mutational Analysis; Dopamine; Female; Gene Expression Regulation, Enzymologic; Gene Frequency; Genetic Markers; Genetic Predisposition to Disease; Genetic Testing; Genotype; Humans; Longitudinal Studies; Male; Neuropsychological Tests; Racial Groups; Time Factors; Valine; White People

2010
COMT and anxiety and cognition in children with chromosome 22q11.2 deletion syndrome.
    Psychiatry research, 2010, Jul-30, Volume: 178, Issue:2

    Topics: Adolescent; Anxiety; Catechol O-Methyltransferase; Child; Cognition Disorders; DiGeorge Syndrome; Executive Function; Female; Genetic Predisposition to Disease; Genotype; Humans; Male; Methionine; Neuropsychological Tests; Polymorphism, Single Nucleotide; Psychiatric Status Rating Scales; Valine

2010
Catechol O-methyltransferase variants and cognitive performance in schizophrenia and bipolar disorder versus controls.
    Schizophrenia research, 2010, Volume: 122, Issue:1-3

    Topics: Adult; Analysis of Variance; Bipolar Disorder; Catechol O-Methyltransferase; Cognition Disorders; Female; Gene Frequency; Genotype; Humans; Male; Methionine; Neuropsychological Tests; Norway; Polymorphism, Single Nucleotide; Schizophrenia; Valine

2010
Effects of BDNF Val66Met polymorphism on brain metabolism in Alzheimer's disease.
    Neuroreport, 2010, Aug-23, Volume: 21, Issue:12

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amino Acid Substitution; Basal Metabolism; Brain; Brain Mapping; Brain-Derived Neurotrophic Factor; Cognition Disorders; Female; Genetic Carrier Screening; Genetic Predisposition to Disease; Humans; Male; Methionine; Middle Aged; Polymorphism, Single Nucleotide; Positron-Emission Tomography; Valine

2010
The roles of COMT val158met status and aviation expertise in flight simulator performance and cognitive ability.
    Behavior genetics, 2011, Volume: 41, Issue:5

    Topics: Adult; Age Factors; Aged; Aircraft; Aviation; Catechol O-Methyltransferase; Cognition; Cognition Disorders; Computer Simulation; Female; Humans; Male; Methionine; Middle Aged; Neuropsychological Tests; Polymorphism, Genetic; Valine

2011
Time course of glucose metabolism in relation to cognitive performance and postmortem neuropathology in Met146Val PSEN1 mutation carriers.
    Journal of Alzheimer's disease : JAD, 2011, Volume: 24, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Brain; Brain Mapping; Cognition Disorders; Female; Fluorodeoxyglucose F18; Glucose; Humans; Male; Mental Status Schedule; Methionine; Middle Aged; Mutation; Neuropsychological Tests; Plaque, Amyloid; Positron-Emission Tomography; Postmortem Changes; Presenilin-1; Statistics as Topic; Time Factors; Valine

2011
Hippocampal volume and the brain-derived neurotrophic factor Val66Met polymorphism in first episode psychosis.
    Schizophrenia research, 2012, Volume: 134, Issue:2-3

    Topics: Adolescent; Adult; Age Factors; Analysis of Variance; Brain-Derived Neurotrophic Factor; Cognition Disorders; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Hippocampus; Humans; Magnetic Resonance Imaging; Male; Memory; Methionine; Neuropsychological Tests; Polymorphism, Single Nucleotide; Psychotic Disorders; Valine; Young Adult

2012
A second look: no effect of the COMT Val158Met polymorphism on conflict adaptation in youth with chromosome 22q11.2 deletion syndrome.
    Schizophrenia research, 2012, Volume: 135, Issue:1-3

    Topics: 22q11 Deletion Syndrome; Adaptation, Psychological; Adolescent; Catechol O-Methyltransferase; Child; Cognition Disorders; Conflict, Psychological; Female; Genetic Association Studies; Humans; Male; Methionine; Neuropsychological Tests; Polymorphism, Single Nucleotide; Valine

2012
The 129 codon polymorphism of the prion protein gene influences earlier cognitive performance in Down syndrome subjects.
    Journal of neurology, 2003, Volume: 250, Issue:6

    Topics: Adolescent; Adult; Age Factors; Alleles; Amino Acid Substitution; Apolipoprotein E4; Apolipoproteins E; Child; Child, Preschool; Codon; Cognition Disorders; Down Syndrome; Female; Follow-Up Studies; Gene Frequency; Genotype; Humans; Intelligence Tests; Male; Methionine; Mutation; Polymorphism, Genetic; Prions; Valine

2003
Association study of a functional catechol-O-methyltransferase genetic polymorphism with age of onset, cognitive function, symptomatology and prognosis in chronic schizophrenia.
    Neuropsychobiology, 2004, Volume: 49, Issue:4

    Topics: Adolescent; Adult; Age of Onset; Aged; Catechol O-Methyltransferase; Chronic Disease; Cognition Disorders; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Male; Methionine; Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic; Prognosis; Psychiatric Status Rating Scales; Regression Analysis; Schizophrenia; Severity of Illness Index; Valine

2004
Hippocalcin-deficient mice display a defect in cAMP response element-binding protein activation associated with impaired spatial and associative memory.
    Neuroscience, 2005, Volume: 133, Issue:2

    Topics: Animals; Association Learning; Avoidance Learning; Behavior, Animal; Blotting, Western; Brain; Cadmium Chloride; Calcium Channel Blockers; Calcium-Binding Proteins; Choice Behavior; Cognition Disorders; Cyclic AMP Response Element-Binding Protein; Discrimination Learning; Dizocilpine Maleate; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Flavonoids; Hippocalcin; Hippocampus; Immunohistochemistry; In Vitro Techniques; Male; Maze Learning; Mice; Mice, Knockout; Motor Activity; N-Methylaspartate; Nerve Tissue Proteins; Nimodipine; Phosphorylation; Potassium Chloride; Psychomotor Performance; Reaction Time; Rotarod Performance Test; Spatial Behavior; Valine

2005
COMT Val108/158 Met modifies mismatch negativity and cognitive function in 22q11 deletion syndrome.
    Biological psychiatry, 2005, Jul-01, Volume: 58, Issue:1

    Topics: Acoustic Stimulation; Adolescent; Adult; Catechol O-Methyltransferase; Child; Chromosomes, Human, Pair 22; Cognition Disorders; Electroencephalography; Evoked Potentials, Auditory; Female; Frontal Lobe; Gene Deletion; Genetic Predisposition to Disease; Humans; Male; Methionine; Neuropsychological Tests; Phenotype; Risk Factors; Schizophrenia; Temporal Lobe; Valine

2005
Catechol-O-methyltransferase Val158Met polymorphism in schizophrenia: associations with cognitive and motor impairment.
    Neuropsychobiology, 2005, Volume: 52, Issue:2

    Topics: Adolescent; Adult; Analysis of Variance; Case-Control Studies; Catechol O-Methyltransferase; Chi-Square Distribution; Cognition Disorders; Confidence Intervals; DNA Mutational Analysis; Female; Genotype; Humans; Male; Methionine; Middle Aged; Motor Skills Disorders; Neuropsychological Tests; Odds Ratio; Polymorphism, Genetic; Psychiatric Status Rating Scales; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Schizophrenia; Schizophrenic Psychology; Valine

2005
Prefrontal cognition in schizophrenia and bipolar illness in relation to Val66Met polymorphism of the brain-derived neurotrophic factor gene.
    Psychiatry and clinical neurosciences, 2006, Volume: 60, Issue:1

    Topics: Adolescent; Adult; Aged; Bipolar Disorder; Brain-Derived Neurotrophic Factor; Catechol O-Methyltransferase; Cognition Disorders; Female; Genotype; Humans; Male; Middle Aged; Neuropsychological Tests; Phenotype; Polymorphism, Genetic; Prefrontal Cortex; Schizophrenia; Schizophrenic Psychology; Statistics as Topic; Valine; Wechsler Scales

2006
No evidence for an effect of COMT Val158Met genotype on executive function in patients with 22q11 deletion syndrome.
    The American journal of psychiatry, 2006, Volume: 163, Issue:3

    Topics: Adolescent; Adult; Catechol O-Methyltransferase; Child; Cognition Disorders; DiGeorge Syndrome; Female; Frontal Lobe; Gene Expression; Genetic Predisposition to Disease; Genotype; Humans; Male; Methionine; Neuropsychological Tests; Polymorphism, Genetic; Valine

2006
Associations between COMTVal158Met polymorphism and cognition: direct or indirect effects?
    European psychiatry : the journal of the Association of European Psychiatrists, 2006, Volume: 21, Issue:5

    Topics: Adult; Alleles; Attention; Catechol O-Methyltransferase; Cognition Disorders; Female; Genetic Predisposition to Disease; Genotype; Humans; Male; Methionine; Middle Aged; Neuropsychological Tests; Polymorphism, Genetic; Reaction Time; Risk; Schizophrenia; Schizotypal Personality Disorder; Valine

2006
Cognitive and magnetic resonance imaging brain morphometric correlates of brain-derived neurotrophic factor Val66Met gene polymorphism in patients with schizophrenia and healthy volunteers.
    Archives of general psychiatry, 2006, Volume: 63, Issue:7

    Topics: Adult; Brain; Brain Mapping; Brain-Derived Neurotrophic Factor; Cognition Disorders; Female; Genetic Variation; Genotype; Hippocampus; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Methionine; Neuropsychological Tests; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Schizophrenia; Schizophrenic Psychology; Temporal Lobe; Valine

2006
The high-activity Val allele of the catechol-O-methyltransferase gene predicts greater cognitive deterioration in patients with psychosis.
    Psychiatric genetics, 2006, Volume: 16, Issue:5

    Topics: Adolescent; Adult; Aged; Alleles; Catechol O-Methyltransferase; Cognition Disorders; Female; Humans; Male; Middle Aged; Psychotic Disorders; Valine

2006
COMT val108/158met genotype, cognitive function, and cognitive improvement with clozapine in schizophrenia.
    Schizophrenia research, 2007, Volume: 90, Issue:1-3

    Topics: Adult; Antipsychotic Agents; Catechol O-Methyltransferase; Clozapine; Cognition Disorders; Cohort Studies; Female; Follow-Up Studies; Genotype; Heterozygote; Homozygote; Humans; Male; Memory, Short-Term; Methionine; Neuropsychological Tests; Polymorphism, Single Nucleotide; Problem Solving; Prospective Studies; Schizophrenia; Treatment Outcome; Valine

2007
Influence of catechol-O-methyltransferase Val158Met polymorphism on neuropsychological and functional outcomes of classical rehabilitation and cognitive remediation in schizophrenia.
    Neuroscience letters, 2007, May-07, Volume: 417, Issue:3

    Topics: Amino Acid Substitution; Brain; Brain Chemistry; Catechol O-Methyltransferase; Cognition Disorders; Cognitive Behavioral Therapy; DNA Mutational Analysis; Female; Genetic Markers; Genetic Predisposition to Disease; Genetic Testing; Genotype; Humans; Male; Methionine; Neuropsychological Tests; Polymorphism, Genetic; Quality of Life; Recovery of Function; Schizophrenia; Treatment Outcome; Valine

2007
Effects of a functional COMT polymorphism on brain anatomy and cognitive function in adults with velo-cardio-facial syndrome.
    Psychological medicine, 2008, Volume: 38, Issue:1

    Topics: Adult; Brain; Catechol O-Methyltransferase; Chromosome Deletion; Chromosomes, Human, Pair 22; Cognition Disorders; DiGeorge Syndrome; Female; Gene Frequency; Humans; Hypertrophy; Male; Methionine; Neuropsychological Tests; Polymorphism, Genetic; Psychotic Disorders; Valine

2008
Brain-derived neurotrophic factor polymorphism Val66Met influences cognitive abilities in the elderly.
    Genes, brain, and behavior, 2008, Volume: 7, Issue:4

    Topics: Aged; Aged, 80 and over; Alleles; Amino Acid Substitution; Atrophy; Brain-Derived Neurotrophic Factor; Cognition Disorders; Cohort Studies; DNA Mutational Analysis; Female; Genetic Predisposition to Disease; Genetic Testing; Genotype; Hippocampus; Humans; Magnetic Resonance Imaging; Male; Memory; Memory Disorders; Methionine; Middle Aged; Mutation; Neuropsychological Tests; Polymorphism, Genetic; Valine

2008
Association between brain-derived neurotrophic factor Val66Met gene polymorphism and progressive brain volume changes in schizophrenia.
    The American journal of psychiatry, 2007, Volume: 164, Issue:12

    Topics: Adult; Antipsychotic Agents; Atrophy; Brain; Brain-Derived Neurotrophic Factor; Cognition Disorders; Female; Frontal Lobe; Genetic Variation; Genotype; Humans; Longitudinal Studies; Magnetic Resonance Imaging; Male; Methionine; Neuronal Plasticity; Neuropsychological Tests; Polymorphism, Genetic; Schizophrenia; Schizophrenic Psychology; Severity of Illness Index; Valine

2007
Association study of a functional catechol-O-methyltransferase polymorphism and executive function in elderly males without dementia.
    Neuroscience letters, 2008, May-09, Volume: 436, Issue:2

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Attention; Catechol O-Methyltransferase; Cognition Disorders; Genetic Predisposition to Disease; Genotype; Geriatric Assessment; Humans; Male; Methionine; Neuropsychological Tests; Polymorphism, Genetic; Problem Solving; Psychomotor Performance; Valine

2008
[Cognitive function, serum BDNF levels and BDNF gene Val66Met polymorphism in amnestic mild cognitive impairment].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2008, Volume: 33, Issue:4

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amnesia; Brain-Derived Neurotrophic Factor; Cognition Disorders; Female; Humans; Male; Methionine; Polymorphism, Genetic; Valine

2008