Compounds > valine

valine and Carcinoma, Hepatocellular

valine has been researched along with Carcinoma, Hepatocellular in 51 studies

Research

Studies (51)

TimeframeStudies, this research(%)All Research%
pre-199010 (19.61)18.7374
1990's2 (3.92)18.2507
2000's4 (7.84)29.6817
2010's25 (49.02)24.3611
2020's10 (19.61)2.80

Authors

AuthorsStudies
Abdel-Bary, HM; El Sayed, IET; Ghanm, SE; Othman Saad, W; Saad, BF; Shebl, NA1
Jang, JY; Jun, DW; Jung, YK; Kim, MY; Kim, SG; Kwon, OS; Lee, JW; Lee, SH; Park, JY; Yoo, HW1
Kim, B; Park, C; Park, T1
Hirayama, A; Ikemoto, T; Imura, S; Kinoshita, S; Morine, Y; Saito, Y; Shimada, M; Tanaka, Y; Utsunomiya, T; Yamada, S; Yamanaka-Okumura, H1
Aguilar, H; Asatryan, A; Bondin, M; Cacoub, P; Carvalho, A; Castro, RE; Charafeddine, M; Cohen, DE; Dieterich, D; Felizarta, F; Hu, YB; Khan, N; Marinho, RT; Poordad, F; Siddique, A1
Abou-Samra, AB; Butt, AA; Nasir, B; Rasool, S; Rubi, G; Tayyab, GUN1
Arai, J; Fukumura, Y; Imai, M; Kato, J; Kojima, K; Kondo, M; Kurokawa, K; Mori, M; Ohki, T; Seki, M; Shibata, C; Tagawa, K; Takagi, K; Toda, N1
Fujisaki, K; Hashiguchi, M; Hiramine, Y; Hori, T; Ido, A; Ijuin, S; Imanaka, D; Inada, Y; Kanmura, S; Kumagai, K; Kure, T; Mawatari, S; Moriuchi, A; Oda, K; Saisyoji, A; Sakae, H; Sakurai, K; Tabu, K; Tamai, T; Taniyama, O; Toyodome, A; Uto, H1
Chen, SC; Cheng, TS; Chuang, WL; Dai, CY; Hsieh, PH; Huang, CF; Huang, CI; Huang, JF; Liang, PC; Lin, ZY; Yeh, ML; Yu, ML1
Feng, F; Jia, H; Wang, Z; Zhang, J1
Chen, L; Cheung, TT; Lee, TK; Lo, CM; Olson, P; Wang, XQ; Wu, CX; Xu, A; Zhang, CC1
Fujikawa, T; Iwabuchi, S; Matsui, K; Nagata, M; Nakano, M; Nakazaki, H; Shimizu, H; Takatsuka, K; Tanemura, H; Watanabe, T1
Aikata, H; Chayama, K; Daijo, K; Fujino, H; Hatooka, M; Hayes, CN; Hiramatsu, A; Honda, F; Imamura, M; Kan, H; Kawakami, Y; Kawaoka, T; Kobayashi, T; Masaki, K; Miki, D; Morio, K; Morio, R; Nagaoki, Y; Nakahara, T; Nakamura, Y; Ochi, H; Ono, A; Teraoka, Y; Tsuge, M1
Rostkowska, K; Simon, K; Szymanek-Pasternak, A1
Arizumi, T; Chishina, H; Hagiwara, S; Ida, H; Kono, M; Kudo, M; Minami, T; Minami, Y; Nishida, N; Takita, M; Ueshima, K; Yada, N1
Al-Zoairy, R; Beinhardt, S; Ferenci, P; Graziadei, I; Hofer, H; Kozbial, K; Maieron, A; Rasoul-Rockenschaub, S; Stättermayer, AF; Stauber, R; Strasser, M; Trauner, M; Zoller, H1
Akuta, N; Chayama, K; Fujiyama, S; Ido, A; Ikeda, F; Inada, Y; Ishikawa, H; Karino, Y; Kumada, H; McPhee, F; Naganuma, A; Noviello, S; Takaguchi, K; Tanaka, K; Tomita, E; Toyota, J; Watanabe, H; Yoshiji, H1
Aghemo, A; Aglitti, A; Andreone, P; Boccaccio, V; Bollani, S; Brunetto, MR; Bruno, S; Calvaruso, V; Ciancio, A; Coco, B; Conti, F; Degasperi, E; Di Leo, A; Di Marco, V; Giorgini, A; Lampertico, P; Lleo, A; Maisonneuve, P; Marzi, L; Persico, M; Rendina, M; Troshina, G; Villa, E; Zuin, M1
Abbas, B; Asem, N; Elsharkawy, A; Esmat, G; Gomaa, A; Hassany, M; Maged, A; Mehrez, M; Mostafa, Z; Soliman, M1
Berak, H; Białkowska, J; Bolewska, B; Fleischer-Stępniewska, K; Flisiak, R; Garlicki, A; Janczewska, E; Karpińska, E; Karwowska, K; Nazzal, K; Piekarska, A; Simon, K; Tomasiewicz, K; Tronina, O; Tuchendler, E; Zarębska-Michaluk, D; Łucejko, M1
Giménez-Manzorro, A; Herranz-Alonso, A; Matilla-Peña, A; Revuelta-Herrero, JL; Sanjurjo-Sáez, M1
Angelidakis, G; Blechacz, B; Economides, MP; Granwehr, BP; Hosry, J; Jiang, Y; Kaseb, A; Kyvernitakis, A; Mahale, P; Miller, E; Naing, A; Raad, II; Samaniego, F; Torres, HA1
Addeo, P; Bachellier, P; Besch, C; Cicek, AE; Faitot, F; Namer, IJ; Oncioiu, C; Ruhland, E1
Baicus, C; Constantinescu, I; Diculescu, M; Dumitru, R; Gavrila, D; Istratescu, D; Manuc, M; Manuc, T; Oproiu, A; Preda, CM; Sandra, I; Tieranu, C; Vasilescu, C; Voiosu, T1
Bukh, J; Gottwein, JM; Humes, D; Jensen, SB; Li, YP; Ramirez, S1
Chung, JW; Kim, DH; Kim, KW; Kim, SJ; Kim, YI; Lee, HK; Lee, JM; Park, J; Tseng, JC; Youn, H1
Andreone, P; Gamal, N; Vitale, G1
Hatae, T; Hayashi, Y; Imoto, S; Kim, KI; Kim, SK; Kim, SR; Kudo, M; Ohtani, A; Sugimoto, K; Tohyama, M; Yano, Y1
Antonov, K; Atanasova, E; Boyanova, Y; Jelev, D; Krastev, Z; Mateva, L; Petkova, T; Tomov, B; Zheleva, N1
Johnson, S; Marx, SE; Misurski, D; Parisé, H; Saab, S; Sanchez Gonzalez, Y; Virabhak, S; Wang, A1
Gonzalez, YS; Johnson, S; Juday, T; Misurski, D; Parisé, H; Saab, S; Virabhak, S; Wang, A1
Asahina, Y; Asano, Y; Azuma, S; Goto, F; Itsui, Y; Kakinuma, S; Kaneko, S; Kawai-Kitahata, F; Miyoshi, M; Murakawa, M; Nagata, H; Nakagawa, M; Nishimura-Sakurai, Y; Nitta, S; Otani, S; Tohda, S; Tojo, N; Tsunoda, T; Watanabe, M1
Akuta, N; Arase, Y; Fujiyama, S; Hosaka, T; Ikeda, K; Kawamura, Y; Kobayashi, M; Kumada, H; Saitoh, S; Sezaki, H; Suzuki, F; Suzuki, Y1
Botta-Fridlund, D; Hachicha, M1
Albillos, A; Ampuero, J; Arenas, J; Bañares, R; Calleja, JL; Crespo, J; Diago, M; Fernandez, I; García-Eliz, M; García-Samaniego, J; Gea, F; Jorquera, F; Lens, S; Llaneras, J; Llerena, S; Mariño, Z; Morillas, RM; Muñoz, R; Navascues, CA; Pascasio, JM; Perelló, C; Rincón, D; Rodriguez, CF; Ruiz-Antorán, B; Sacristán, B; Serra, MA; Simon, MA; Torras, X; Turnes, J1
Beaugrand, M; Charnaux, N; Friand, V; Gattegno, L; Lièvre, N; Nahon, P; Pessayre, D; Prost-Squarcioni, C; Sutton, A; Trinchet, JC; Ziol, M1
MORRIS, HP; WAGLE, SR; WEBER, G1
Chen, M; Cheng, T; Ou, SH; Wu, T; Xia, NS; Xu, CY; Zhang, J; Zhang, T1
Afifi, R; Benazzouz, M; Benjelloun, S; Chafik, A; El Feydi, AE; El Kihal, L; Ezzikouri, S; Hassar, M; Pineau, P1
Fujitsuka, N; Harada, A; Harris, RA; Hutson, SM; Kurokawa, T; Nakao, A; Nonami, T; Shimomura, Y; Sugiyama, S; Takagi, H; Taniguchi, K1
Etlinger, JD; Ndubuisi, MI; Rayanade, RJ; Sehgal, PB1
Inoue, S; Ishigure, K; Kaneko, T; Koshikawa, K; Murakami, T; Nakao, A; Nomoto, S; Nonami, T; Shimomura, Y; Takeda, S1
Ichihara, A1
Colten, HR; Strunk, RC; Tashjian, AH1
Fukushima, K; Toyoshima, S1
Goto, M; Ichihara, A; Shinno, H1
Jost, JP; Pitot, HC1
Ichihara, A; Ogawa, K; Yokojima, A1
Beck, JP; Befort, N; Ebel, JP; Mercier, J1
Bayev, AA; Shershneva, LP; Venkstern, TV2

Reviews

2 review(s) available for valine and Carcinoma, Hepatocellular

ArticleYear
γ-Secretase inhibitors for breast cancer and hepatocellular carcinoma: From mechanism to treatment.
    Life sciences, 2021, Mar-01, Volume: 268

    Topics: Amyloid Precursor Protein Secretases; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Hepatocellular; Female; Humans; Liver Neoplasms; Oligopeptides; Protease Inhibitors; Receptors, Notch; Tetrahydronaphthalenes; Valine

2021
ABT-450: a novel agent for the treatment of CHC genotype 1: focus on treatment-experienced patients.
    Expert review of anti-infective therapy, 2015, Volume: 13, Issue:3

    Topics: 2-Naphthylamine; Anilides; Antiviral Agents; Carbamates; Carcinoma, Hepatocellular; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cyclopropanes; Drug Interactions; Drug Resistance, Viral; Drug Therapy, Combination; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Lactams, Macrocyclic; Liver Cirrhosis; Liver Neoplasms; Macrocyclic Compounds; Proline; Protease Inhibitors; Randomized Controlled Trials as Topic; Ribavirin; Ritonavir; RNA, Viral; Sulfonamides; Uracil; Valine

2015

Trials

1 trial(s) available for valine and Carcinoma, Hepatocellular

ArticleYear
Long-term safety and efficacy results in hepatitis C virus genotype 1-infected patients receiving ombitasvir/paritaprevir/ritonavir + dasabuvir ± ribavirin in the TOPAZ-I and TOPAZ-II trials.
    Journal of viral hepatitis, 2020, Volume: 27, Issue:5

    Topics: 2-Naphthylamine; Anilides; Antiviral Agents; Carcinoma, Hepatocellular; Cyclopropanes; Drug Therapy, Combination; Genotype; Hepacivirus; Hepatitis C; Humans; Lactams, Macrocyclic; Liver Neoplasms; Proline; Ribavirin; Ritonavir; Sulfonamides; Sustained Virologic Response; Uracil; Valine

2020

Other Studies

48 other study(ies) available for valine and Carcinoma, Hepatocellular

ArticleYear
Direct Relationship between Interleukin-10 Gene Polymorphism and Hepatocellular Carcinoma Complicated by Direct Acting Antiviral Treatment of Hepatitis C Virus.
    Asian Pacific journal of cancer prevention : APJCP, 2021, Oct-01, Volume: 22, Issue:10

    Topics: Adult; Aged; Antiviral Agents; Ascites; Carbamates; Carcinoma, Hepatocellular; Drug Therapy, Combination; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Imidazoles; Interleukin-10; Liver Cirrhosis; Liver Neoplasms; Lymphadenitis; Male; Middle Aged; Polymorphism, Single Nucleotide; Pyrrolidines; Ribavirin; Simeprevir; Sofosbuvir; Splenomegaly; Valine

2021
Regression of liver fibrosis and hepatocellular carcinoma development after HCV eradication with oral antiviral agents.
    Scientific reports, 2022, 01-07, Volume: 12, Issue:1

    Topics: Administration, Oral; Aged; Antiviral Agents; Carbamates; Carcinoma, Hepatocellular; Drug Therapy, Combination; Elasticity Imaging Techniques; Female; Hepatitis C, Chronic; Humans; Imidazoles; Incidence; Interferons; Isoquinolines; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Prospective Studies; Pyrrolidines; Retrospective Studies; Ribavirin; Seoul; Sulfonamides; Sustained Virologic Response; Time Factors; Treatment Outcome; Valine

2022
DeepHisCoM: deep learning pathway analysis using hierarchical structural component models.
    Briefings in bioinformatics, 2022, 09-20, Volume: 23, Issue:5

    Topics: Biological Factors; Carcinoma, Hepatocellular; COVID-19; Deep Learning; Gonadotropin-Releasing Hormone; Humans; Isoleucine; Leucine; Liver Neoplasms; Lysine; Mitogen-Activated Protein Kinases; Phenylalanine; Tryptophan; Tyrosine; Valine

2022
Essential amino acids as diagnostic biomarkers of hepatocellular carcinoma based on metabolic analysis.
    Oncotarget, 2022, 11-22, Volume: 13

    Topics: Amino Acids, Essential; Carcinoma, Hepatocellular; Humans; Leucine; Liver Neoplasms; Tryptophan; Valine

2022
Hepatocellular carcinoma occurs frequently and early after treatment in HCV genotype 3 infected persons treated with DAA regimens.
    BMC gastroenterology, 2020, Apr-06, Volume: 20, Issue:1

    Topics: Adult; Antiviral Agents; Carbamates; Carcinoma, Hepatocellular; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Imidazoles; Interferons; Kaplan-Meier Estimate; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Pakistan; Polyethylene Glycols; Proportional Hazards Models; Prospective Studies; Pyrrolidines; Ribavirin; Sofosbuvir; Sustained Virologic Response; Time Factors; Tomography, X-Ray Computed; Valine

2020
Hepatitis C virus relapse after successful treatment with direct-acting antivirals, followed by sarcomatous changes in hepatocellular carcinoma: a case report.
    Journal of medical case reports, 2020, May-27, Volume: 14, Issue:1

    Topics: Aged; Antiviral Agents; Carbamates; Carcinoma, Hepatocellular; Fatal Outcome; Hepacivirus; Hepatitis C; Humans; Imidazoles; Isoquinolines; Liver Neoplasms; Male; Neoplasm Recurrence, Local; Pyrrolidines; Radiofrequency Ablation; Recurrence; Sulfonamides; Valine; Viral Load

2020
Hypovascular tumors developed into hepatocellular carcinoma at a high rate despite the elimination of hepatitis C virus by direct-acting antivirals.
    PloS one, 2020, Volume: 15, Issue:8

    Topics: Aged; alpha-Fetoproteins; Antiviral Agents; Carbamates; Carcinoma, Hepatocellular; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Imidazoles; Incidence; Isoquinolines; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Proportional Hazards Models; Pyrrolidines; Risk Factors; Sulfonamides; Sustained Virologic Response; Valine

2020
Real-world effectiveness of direct-acting antiviral agents for chronic hepatitis C patients with genotype-2 infection after completed treatment.
    The Kaohsiung journal of medical sciences, 2021, Volume: 37, Issue:4

    Topics: Age Factors; Aged; Antiviral Agents; Benzimidazoles; Carbamates; Carcinoma, Hepatocellular; Drug Combinations; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Heterocyclic Compounds, 4 or More Rings; Humans; Imidazoles; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Multivariate Analysis; Pyrrolidines; Quinoxalines; Retrospective Studies; Ribavirin; Sofosbuvir; Sulfonamides; Taiwan; Treatment Outcome; Valine

2021
Notch Inhibitor PF-03084014 Inhibits Hepatocellular Carcinoma Growth and Metastasis via Suppression of Cancer Stemness due to Reduced Activation of Notch1-Stat3.
    Molecular cancer therapeutics, 2017, Volume: 16, Issue:8

    Topics: Antineoplastic Agents; Carcinogenesis; Carcinoma, Hepatocellular; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell Self Renewal; Humans; Liver Neoplasms; Neoplasm Metastasis; Neoplastic Stem Cells; Receptor, Notch1; Spheroids, Cellular; STAT3 Transcription Factor; Tetrahydronaphthalenes; Valine

2017
Relationship of hepatitis B virus infection to the recurrence of hepatocellular carcinoma after direct acting antivirals.
    Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2017, Volume: 36, Issue:3

    Topics: Aged; Aged, 80 and over; Antibodies, Viral; Antiviral Agents; Carbamates; Carcinoma, Hepatocellular; Drug Therapy, Combination; Female; Hepatitis B Core Antigens; Hepatitis C, Chronic; Humans; Imidazoles; Liver Neoplasms; Male; Neoplasm Recurrence, Local; Pyrrolidines; Retrospective Studies; Ribavirin; Risk Factors; Sofosbuvir; Valine

2017
The risks of hepatocellular carcinoma development after HCV eradication are similar between patients treated with peg-interferon plus ribavirin and direct-acting antiviral therapy.
    PloS one, 2017, Volume: 12, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antiviral Agents; Carbamates; Carcinoma, Hepatocellular; Drug Therapy, Combination; Hepatitis C, Chronic; Humans; Imidazoles; Incidence; Interferon-alpha; Isoquinolines; Kaplan-Meier Estimate; Liver Neoplasms; Middle Aged; Proportional Hazards Models; Pyrrolidines; Ribavirin; Risk Factors; Sulfonamides; Treatment Outcome; Valine; Viral Load; Young Adult

2017
Successful twice interrupted therapy of HCV infection in patients with cirrhosis with hepatocellular carcinoma before and after liver transplantation.
    BMJ case reports, 2017, Sep-15, Volume: 2017

    Topics: 2-Naphthylamine; Anilides; Antiviral Agents; Carbamates; Carcinoma, Hepatocellular; Cyclopropanes; Drug Therapy, Combination; Hepatitis C; Humans; Lactams, Macrocyclic; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Macrocyclic Compounds; Male; Middle Aged; Proline; Ribavirin; Ritonavir; Sulfonamides; Sustained Virologic Response; Treatment Outcome; Uracil; Valine

2017
Hepatocellular Carcinoma after Achievement of Sustained Viral Response with Daclatasvir and Asunaprevir in Patients with Chronic Hepatitis C Virus Infection.
    Digestive diseases (Basel, Switzerland), 2017, Volume: 35, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; alpha-Fetoproteins; Antiviral Agents; Carbamates; Carcinoma, Hepatocellular; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Imidazoles; Isoquinolines; Liver Neoplasms; Male; Middle Aged; Multivariate Analysis; Neoplasm Recurrence, Local; Proportional Hazards Models; Pyrrolidines; Risk Factors; Sulfonamides; Sustained Virologic Response; Tomography, X-Ray Computed; Valine

2017
Long-term follow-up of ribavirin-free DAA-based treatment in HCV recurrence after orthotopic liver transplantation.
    Liver international : official journal of the International Association for the Study of the Liver, 2018, Volume: 38, Issue:7

    Topics: Aged; Antiviral Agents; Austria; Benzimidazoles; Carbamates; Carcinoma, Hepatocellular; Drug Therapy, Combination; Female; Fluorenes; Follow-Up Studies; Hepacivirus; Hepatitis C, Chronic; Humans; Imidazoles; Liver Neoplasms; Liver Transplantation; Male; Middle Aged; Pyrrolidines; Recurrence; Ribavirin; Simeprevir; Sofosbuvir; Sustained Virologic Response; Valine

2018
Potent viral suppression and improvements in alpha-fetoprotein and measures of fibrosis in Japanese patients receiving a daclatasvir/asunaprevir/beclabuvir fixed-dose combination for the treatment of HCV genotype-1 infection.
    Journal of gastroenterology, 2018, Volume: 53, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; alpha-Fetoproteins; Antiviral Agents; Benzazepines; Biopsy; Carbamates; Carcinoma, Hepatocellular; Drug Therapy, Combination; Elasticity Imaging Techniques; Female; Follow-Up Studies; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Imidazoles; Indoles; Isoquinolines; Japan; Liver Cirrhosis; Male; Middle Aged; Pyrrolidines; Sulfonamides; Sustained Virologic Response; Treatment Outcome; Valine

2018
High efficacy of direct-acting anti-viral agents in hepatitis C virus-infected cirrhotic patients with successfully treated hepatocellular carcinoma.
    Alimentary pharmacology & therapeutics, 2018, Volume: 47, Issue:12

    Topics: Aged; Antiviral Agents; Benzimidazoles; Carbamates; Carcinoma, Hepatocellular; Cohort Studies; Drug Therapy, Combination; Female; Fluorenes; Genotype; Hepacivirus; Hepatic Encephalopathy; Hepatitis C, Chronic; Humans; Imidazoles; Interferons; Italy; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Prospective Studies; Pyrrolidines; Ribavirin; Simeprevir; Sofosbuvir; Sustained Virologic Response; Uridine Monophosphate; Valine

2018
Hepatitis C virus treatment by direct-acting antivirals in successfully treated hepatocellular carcinoma and possible mutual impact.
    European journal of gastroenterology & hepatology, 2018, Volume: 30, Issue:8

    Topics: Aged; Antiviral Agents; Carbamates; Carcinoma, Hepatocellular; Drug Therapy, Combination; Egypt; Female; Hepatitis C; Humans; Imidazoles; Incidence; Liver Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Prospective Studies; Pyrrolidines; Ribavirin; Risk Factors; Simeprevir; Sofosbuvir; Sustained Virologic Response; Time Factors; Treatment Outcome; Valine

2018
Durability of virologic response, risk of de novo hepatocellular carcinoma, liver function and stiffness 2 years after treatment with ombitasvir/paritaprevir/ritonavir±dasabuvir±ribavirin in the AMBER, real-world experience study.
    Journal of viral hepatitis, 2018, Volume: 25, Issue:11

    Topics: 2-Naphthylamine; Adult; Aged; Anilides; Antiviral Agents; Carbamates; Carcinoma, Hepatocellular; Cyclopropanes; Drug Therapy, Combination; Female; Follow-Up Studies; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Lactams, Macrocyclic; Liver; Liver Cirrhosis; Liver Neoplasms; Macrocyclic Compounds; Male; Middle Aged; Poland; Proline; Ribavirin; Ritonavir; Sulfonamides; Treatment Outcome; Uracil; Valine; Viral Load

2018
Concomitant use of sorafenib with ombitasvir/paritaprevir/ritonavir and dasabuvir: Effectiveness and safety in clinical practice.
    Journal of clinical pharmacy and therapeutics, 2018, Volume: 43, Issue:6

    Topics: 2-Naphthylamine; Aged; Anilides; Antineoplastic Agents; Antiviral Agents; Carbamates; Carcinoma, Hepatocellular; Cyclopropanes; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Lactams, Macrocyclic; Liver Neoplasms; Macrocyclic Compounds; Male; Middle Aged; Proline; Prospective Studies; Ritonavir; Sorafenib; Sulfonamides; Treatment Outcome; Uracil; Valine

2018
Sofosbuvir-Based Therapy in Hepatitis C Virus-Infected Cancer Patients: A Prospective Observational Study.
    The American journal of gastroenterology, 2019, Volume: 114, Issue:2

    Topics: Aged; Antiviral Agents; Benzimidazoles; Breast Neoplasms; Carbamates; Carcinoma, Hepatocellular; Drug Therapy, Combination; Female; Fluorenes; Head and Neck Neoplasms; Hepatitis C, Chronic; Heterocyclic Compounds, 4 or More Rings; Humans; Imidazoles; Interferons; Liver Neoplasms; Lymphoma, Non-Hodgkin; Male; Middle Aged; Multiple Myeloma; Neoplasms; Polyethylene Glycols; Prospective Studies; Pyrrolidines; Ribavirin; Simeprevir; Sofosbuvir; Sustained Virologic Response; Valine

2019
Metabolomic profiling highlights the metabolic bases of acute-on-chronic and post-hepatectomy liver failure.
    HPB : the official journal of the International Hepato Pancreato Biliary Association, 2019, Volume: 21, Issue:10

    Topics: Acute-On-Chronic Liver Failure; Aged; Alanine; Biomarkers; Carcinoma, Hepatocellular; Female; Follow-Up Studies; Hepatectomy; Humans; Liver; Liver Neoplasms; Magnetic Resonance Spectroscopy; Male; Metabolomics; Middle Aged; Phosphoric Diester Hydrolases; Postoperative Complications; Retrospective Studies; Risk Factors; ROC Curve; Valine

2019
Recurrence rate of hepatocellular carcinoma in patients with treated hepatocellular carcinoma and hepatitis C virus-associated cirrhosis after ombitasvir/paritaprevir/ritonavir+dasabuvir+ribavirin therapy.
    United European gastroenterology journal, 2019, Volume: 7, Issue:5

    Topics: 2-Naphthylamine; Aged; Anilides; Antiviral Agents; Carbamates; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Cyclopropanes; Hepatectomy; Hepatitis C, Chronic; Humans; Lactams, Macrocyclic; Liver Cirrhosis; Liver Neoplasms; Macrocyclic Compounds; Middle Aged; Neoplasm Recurrence, Local; Proline; Prospective Studies; Radiofrequency Ablation; Ribavirin; Ritonavir; Sulfonamides; Treatment Outcome; Uracil; Valine

2019
Differential sensitivity of 5'UTR-NS5A recombinants of hepatitis C virus genotypes 1-6 to protease and NS5A inhibitors.
    Gastroenterology, 2014, Volume: 146, Issue:3

    Topics: Antiviral Agents; Carbamates; Carcinoma, Hepatocellular; Carrier Proteins; Cell Line, Tumor; Genotype; Hepacivirus; Humans; Imidazoles; Intracellular Signaling Peptides and Proteins; Liver; Liver Neoplasms; Mutation; Oligopeptides; Proline; Protease Inhibitors; Pyrrolidines; Valine; Viral Nonstructural Proteins

2014
Enhanced efficacy of CKD-516 in combination with doxorubicin: pre-clinical evaluation using a hepatocellular carcinoma xenograft model.
    Anticancer research, 2014, Volume: 34, Issue:4

    Topics: Animals; Apoptosis; Benzophenones; Carcinoma, Hepatocellular; Cell Line, Tumor; Disease Models, Animal; Doxorubicin; Drug Evaluation, Preclinical; Drug Synergism; Humans; Liver Neoplasms; Mice; Necrosis; Neovascularization, Pathologic; Tumor Burden; Valine; Xenograft Model Antitumor Assays

2014
Comparison of Daclatasvir and Asunaprevir for Chronic HCV 1b Infection with Telaprevir and Simeprevir plus Peginterferon and Ribavirin, with a Focus on the Prevention of Occurrence and Recurrence of Hepatocellular Carcinoma.
    Oncology, 2015, Volume: 89 Suppl 2

    Topics: Adult; Aged; Aged, 80 and over; alpha-Fetoproteins; Antiviral Agents; Carbamates; Carcinoma, Hepatocellular; Drug Therapy, Combination; Female; Follow-Up Studies; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Imidazoles; Interferon alpha-2; Interferon-alpha; Isoquinolines; Japan; Liver Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Oligopeptides; Polyethylene Glycols; Polymerase Chain Reaction; Prognosis; Pyrrolidines; Recombinant Proteins; Ribavirin; RNA, Viral; Simeprevir; Sulfonamides; Valine; Viral Load

2015
Ombitasvir, paritaprevir, ritonavir, dasabuvir and ribavirin in cirrhosis after complete destruction of hepatocellular carcinoma.
    World journal of gastroenterology, 2016, Feb-28, Volume: 22, Issue:8

    Topics: 2-Naphthylamine; Aged; Anilides; Antiviral Agents; Carbamates; Carcinoma, Hepatocellular; Cyclopropanes; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C; Humans; Lactams, Macrocyclic; Liver Cirrhosis; Liver Function Tests; Liver Neoplasms; Macrocyclic Compounds; Male; Proline; Ribavirin; Ritonavir; RNA, Viral; Sulfonamides; Treatment Outcome; Uracil; Valine; Viral Load

2016
Cost-effectiveness of currently recommended direct-acting antiviral treatments in patients infected with genotypes 1 or 4 hepatitis C virus in the US.
    Journal of medical economics, 2016, Volume: 19, Issue:8

    Topics: 2-Naphthylamine; Adult; Aged; Aged, 80 and over; Anilides; Antiviral Agents; Benzimidazoles; Carbamates; Carcinoma, Hepatocellular; Cost-Benefit Analysis; Cyclopropanes; Drug Therapy, Combination; Female; Fibrosis; Fluorenes; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Lactams, Macrocyclic; Liver Neoplasms; Macrocyclic Compounds; Male; Markov Chains; Middle Aged; Models, Econometric; Proline; Quality-Adjusted Life Years; Ribavirin; Simeprevir; Sofosbuvir; Sulfonamides; Uracil; Valine

2016
Cost-Effectiveness of Genotype 1 Chronic Hepatitis C Virus Treatments in Patients Coinfected with Human Immunodeficiency Virus in the United States.
    Advances in therapy, 2016, Volume: 33, Issue:8

    Topics: 2-Naphthylamine; Adult; Anilides; Antiviral Agents; Benzimidazoles; Carbamates; Carcinoma, Hepatocellular; Cost-Benefit Analysis; Cyclopropanes; Disease Progression; Drug Therapy, Combination; Fluorenes; Genotype; Hepacivirus; Hepatitis C, Chronic; HIV Infections; Humans; Interferon-alpha; Lactams, Macrocyclic; Liver Cirrhosis; Liver Neoplasms; Macrocyclic Compounds; Markov Chains; Middle Aged; Polyethylene Glycols; Proline; Quality-Adjusted Life Years; Recombinant Proteins; Ribavirin; Ritonavir; Sofosbuvir; Sulfonamides; United States; Uracil; Valine

2016
Serial measurement of Wisteria floribunda agglutinin positive Mac-2-binding protein is useful for predicting liver fibrosis and the development of hepatocellular carcinoma in chronic hepatitis C patients treated with IFN-based and IFN-free therapy.
    Hepatology international, 2016, Volume: 10, Issue:6

    Topics: Antigens, Neoplasm; Antiviral Agents; Biomarkers, Tumor; Carbamates; Carcinoma, Hepatocellular; Carrier Proteins; Early Diagnosis; Female; Glycoproteins; Hepatitis C, Chronic; Humans; Imidazoles; Interferon-alpha; Isoquinolines; Liver Cirrhosis; Liver Neoplasms; Male; Membrane Glycoproteins; Plant Lectins; Pyrrolidines; Sulfonamides; Valine

2016
Liver Fibrosis and Body Mass Index Predict Hepatocarcinogenesis following Eradication of Hepatitis C Virus RNA by Direct-Acting Antivirals.
    Oncology, 2016, Volume: 91, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antiviral Agents; Body Mass Index; Carbamates; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Drug Therapy, Combination; Female; Genotype; Hepacivirus; Hepatitis C, Chronic; Humans; Imidazoles; Interferon Type I; Isoquinolines; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Oligopeptides; Pyrrolidines; Ribavirin; Risk Factors; RNA, Viral; Sulfonamides; Sustained Virologic Response; Valine; Young Adult

2016
[Sofosbuvir and daclatasvir combination therapy in hemodialysis patient with liver transplantation].
    Nephrologie & therapeutique, 2016, Volume: 12, Issue:7

    Topics: Antiviral Agents; Carbamates; Carcinoma, Hepatocellular; Drug Therapy, Combination; Hepatitis C; Humans; Imidazoles; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Male; Middle Aged; Pyrrolidines; Renal Dialysis; Renal Insufficiency, Chronic; Risk Factors; Sofosbuvir; Treatment Outcome; Valine

2016
Effectiveness, safety and clinical outcomes of direct-acting antiviral therapy in HCV genotype 1 infection: Results from a Spanish real-world cohort.
    Journal of hepatology, 2017, Volume: 66, Issue:6

    Topics: 2-Naphthylamine; Adult; Aged; Aged, 80 and over; Anilides; Antiviral Agents; Benzimidazoles; Carbamates; Carcinoma, Hepatocellular; Cohort Studies; Cyclopropanes; Drug Therapy, Combination; Female; Fluorenes; Genotype; Glomerular Filtration Rate; Hepacivirus; Hepatitis C, Chronic; Humans; Lactams, Macrocyclic; Liver Neoplasms; Macrocyclic Compounds; Male; Middle Aged; Neoplasm Recurrence, Local; Proline; Retrospective Studies; Ribavirin; Ritonavir; Sofosbuvir; Spain; Sulfonamides; Sustained Virologic Response; Treatment Outcome; Uracil; Uridine Monophosphate; Valine; Young Adult

2017
The manganese superoxide dismutase Ala16Val dimorphism modulates iron accumulation in human hepatoma cells.
    Free radical biology & medicine, 2008, Nov-01, Volume: 45, Issue:9

    Topics: Alanine; Alcoholism; Alleles; Carcinoma, Hepatocellular; Cell Line; Frataxin; Genotype; Homeostasis; Humans; Iron; Iron-Binding Proteins; Liver Neoplasms; Models, Biological; Plasmids; Superoxide Dismutase; Valine

2008
COMPARATIVE BIOCHEMISTRY OF HEPATOMAS. V. STUDIES ON AMINO ACID INCORPORATION IN LIVER TUMORS OF DIFFERENT GROWTH RATES.
    Cancer research, 1963, Volume: 23

    Topics: Alanine; Amino Acids; Aspartic Acid; Carcinoma, Hepatocellular; Glycine; Histocytochemistry; Isoleucine; Liver Neoplasms; Liver Regeneration; Mice; Neoplasms, Experimental; Proteins; Research; Serine; Valine

1963
[Hydrophobicity of reactive site loop of SCCA1 affects its binding to HBV].
    Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 2005, Volume: 21, Issue:1

    Topics: Antigens, Neoplasm; Binding Sites; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Line, Tumor; Glutamic Acid; Hepatitis B virus; Humans; Hydrophobic and Hydrophilic Interactions; Liver Neoplasms; Protein Binding; Receptors, Virus; Serpins; Valine

2005
Genetic polymorphism in the manganese superoxide dismutase gene is associated with an increased risk for hepatocellular carcinoma in HCV-infected Moroccan patients.
    Mutation research, 2008, Jan-08, Volume: 649, Issue:1-2

    Topics: Aged; Alanine; Carcinoma, Hepatocellular; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Hepatitis C; Humans; Male; Middle Aged; Morocco; Odds Ratio; Polymorphism, Genetic; Risk Factors; Superoxide Dismutase; Valine

2008
The valine catabolic pathway in human liver: effect of cirrhosis on enzyme activities.
    Hepatology (Baltimore, Md.), 1996, Volume: 24, Issue:6

    Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Animals; Carcinoma, Hepatocellular; Enoyl-CoA Hydratase; Female; Humans; Ketone Oxidoreductases; Liver; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Multienzyme Complexes; Rats; Reference Values; Species Specificity; Thiolester Hydrolases; Transaminases; Valine

1996
Regulation of IL-6 signaling by p53: STAT3- and STAT5-masking in p53-Val135-containing human hepatoma Hep3B cell lines.
    Journal of immunology (Baltimore, Md. : 1950), 1998, Jul-01, Volume: 161, Issue:1

    Topics: Amino Acid Substitution; Carcinoma, Hepatocellular; Cytokines; DNA-Binding Proteins; Dose-Response Relationship, Immunologic; Epidermal Growth Factor; Humans; Interferon-gamma; Interleukin-6; Milk Proteins; Mutation; Phenotype; Phosphatidylinositol Diacylglycerol-Lyase; Phosphorylation; Signal Transduction; STAT3 Transcription Factor; STAT5 Transcription Factor; Temperature; Time Factors; Trans-Activators; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Type C Phospholipases; Tyrosine; Valine

1998
Human liver disease decreases methacrylyl-CoA hydratase and beta-hydroxyisobutyryl-CoA hydrolase activities in valine catabolism.
    Clinica chimica acta; international journal of clinical chemistry, 2001, Volume: 312, Issue:1-2

    Topics: Aged; Carcinoma, Hepatocellular; Enoyl-CoA Hydratase; Female; Gene Expression Regulation, Enzymologic; Hepatitis; Humans; Liver; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Male; Middle Aged; Reference Values; Thiolester Hydrolases; Valine

2001
Isozyme patterns of branched-chain amino acid transaminase during cellular differentiation and carcinogenesis.
    Annals of the New York Academy of Sciences, 1975, Aug-22, Volume: 259

    Topics: alpha-Fetoproteins; Animals; Carcinoma, Hepatocellular; Cell Differentiation; Cell Transformation, Neoplastic; Female; Isoenzymes; Isoleucine; Kinetics; Leucine; Liver; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; Neoplasms, Experimental; Organ Specificity; Rats; Transaminases; Valine

1975
Complement biosynthesis in vitro by rat hepatoma cell strains.
    Journal of immunology (Baltimore, Md. : 1950), 1975, Volume: 114, Issue:1 Pt 2

    Topics: Animals; Autoradiography; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Chromatography, Gel; Complement Inactivator Proteins; Complement System Proteins; Cycloheximide; Erythrocytes; Humans; Hydrocortisone; Immune Sera; Immunodiffusion; Immunoelectrophoresis; Isoleucine; Leucine; Liver Neoplasms; Lysine; Male; Rabbits; Rats; Sheep; Valine

1975
Antitumor activity of amino acid derivatives in the primary screening.
    Gan, 1975, Volume: 66, Issue:1

    Topics: 2-Naphthylamine; Amino Acids; Aminobutyrates; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; DNA, Neoplasm; Drug Evaluation, Preclinical; HeLa Cells; Isoleucine; Leukemia, Experimental; Liver Neoplasms; Male; Mice; Mitosis; Neoplasm Proteins; Neoplasms, Experimental; Phenylalanine; Rats; RNA, Neoplasm; Sarcoma, Experimental; Structure-Activity Relationship; Tryptophan; Valine

1975
Isozyme patterns of branched-chain amino acid transaminase in human tissues and tumors.
    Gan, 1977, Volume: 68, Issue:5

    Topics: Animals; Binding, Competitive; Carcinoma, Hepatocellular; Female; Fetus; Humans; In Vitro Techniques; Isoenzymes; Isoleucine; Kidney Neoplasms; Leucine; Liver Neoplasms; Male; Neoplasms; Rats; Species Specificity; Stomach Neoplasms; Substrate Specificity; Tissue Distribution; Transaminases; Valine

1977
Metabolic adaptations in rat hepatomas: altered regulation of serine dehydratase synthesis by glucose and amino acids in hepatocellular carcinomas.
    Cancer research, 1970, Volume: 30, Issue:2

    Topics: Amino Acids; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Glucose; Hydro-Lyases; Immunochemistry; Immunodiffusion; Liver Neoplasms; Neoplasms, Experimental; Rats; Valine

1970
Transaminase of branched chain amino acids. VII. Comparative studies on isozymes of ascites hepatoma and various normal tissues of rat.
    Journal of biochemistry, 1970, Volume: 68, Issue:6

    Topics: Adipose Tissue; Animals; Brain; Carcinoma, Hepatocellular; Chromatography; Chromatography, DEAE-Cellulose; Immunodiffusion; Isoenzymes; Isoleucine; Kidney; Leucine; Liver; Liver Neoplasms; Male; Molecular Weight; Muscles; Neoplasms, Experimental; Rats; Sarcoma, Yoshida; Spleen; Swine; Testis; Transaminases; Ultracentrifugation; Valine

1970
[Comparative study of transfer ribonucleic acids extracted from rat liver and Zajdela hepatoma. I. Study of the acceptor properties of tRNA].
    Biochimie, 1972, Volume: 54, Issue:10

    Topics: Acylation; Alanine; Animals; Arginine; Ascites; Carcinoma, Hepatocellular; Cell Differentiation; Cell Transformation, Neoplastic; Isoleucine; Kinetics; Liver; Liver Neoplasms; Neoplasms, Experimental; Rats; RNA, Transfer; Serine; Transfer RNA Aminoacylation; Valine

1972
A study of transfer RNA methylation.
    Biochimica et biophysica acta, 1973, Jan-19, Volume: 294, Issue:2

    Topics: Animals; Base Sequence; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography, Paper; Chromatography, Thin Layer; Cytosol; Kinetics; Liver; Liver Neoplasms; Methylation; Methyltransferases; Neoplasms, Experimental; Nucleic Acid Conformation; Polynucleotides; Rats; Ribonucleases; RNA, Transfer; Saccharomyces cerevisiae; Structure-Activity Relationship; Transfer RNA Aminoacylation; Valine

1973
A study of transfer RNA methylation.
    Biochimica et biophysica acta, 1973, Jan-19, Volume: 294, Issue:1

    Topics: Animals; Base Sequence; Binding Sites; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography, Paper; Chromatography, Thin Layer; Liver; Liver Neoplasms; Methylation; Methyltransferases; Neoplasms, Experimental; Nucleic Acid Conformation; Rats; Ribonucleotides; RNA, Transfer; Saccharomyces cerevisiae; Spectrophotometry, Ultraviolet; Valine

1973