valine and Amyotrophic Lateral Sclerosis

valine has been researched along with Amyotrophic Lateral Sclerosis in 26 studies

Research

Studies (26)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (7.69)	18.7374
1990's	6 (23.08)	18.2507
2000's	6 (23.08)	29.6817
2010's	10 (38.46)	24.3611
2020's	2 (7.69)	2.80

Authors

Authors	Studies
Andersen, PM; Basal, A; Daana, M; Edvardson, S; Ezer, S; Harel, T; Marklund, SL; Meiner, V; Nordström, U; Otto, M; Park, JH; Saada, A; Yanovsky-Dagan, S	1
Barberis, M; Brunetti, M; Calvo, A; Cammarosano, S; Canosa, A; Chiò, A; De Marco, G; Grassano, M; Manera, U; Moglia, C; Vasta, R	1
Chen, L; Fan, D; Liu, X; Ma, Y; Tang, L	1
Akamatsu, M; Hirano, M; Isono, C; Kusunoki, S; Nakamura, Y; Saigoh, K; Sakamoto, H; Ueno, S	1
An, R; Lin, Z; Xi, J; Xu, Y; Yang, X; Yu, L; Zhou, H	1
Boonen, S; Dubois, B; Goris, A; Hersmus, N; Lemmens, R; Matthijs, G; Race, V; Robberecht, W; Van Damme, P; Van Den Bosch, L	1
Atassi, N; David, WS; Salameh, JS	1
Antonyuk, SV; Galaleldeen, A; Hart, PJ; Hasnain, SS; Holloway, SP; Narayana, N; Schuermann, JP; Strange, RW; Taylor, AB; Whitson, LJ	1
Cruts, M; De Deyn, PP; Engelborghs, S; Gijselinck, I; Mattheijssens, M; Peeters, K; Sleegers, K; Van Broeckhoven, C; Van den Broeck, M; van der Zee, J; Van Langenhove, T; Vandenberghe, R	1
Pamphlett, R	1
Bernardi, G; Caioli, S; Canu, N; Carunchio, I; Curcio, L; Molinari, M; Pica, F; Pieri, M; Viscomi, MT; Zona, C	1
Boylan, K; DeJesus-Hernandez, M; Desaro, P; Ertekin-Taner, N; Graff-Radford, NR; Johnston, A; Rademakers, R; Ross, OA; Wszolek, ZK	1
Allen, MJ; Arnsdorf, MF; Capone, R; Ghadge, GD; Lacroix, JJ; Lal, R; Ramachandran, S; Roos, RP; Whitlock, JL	1
Ikeuchi, T; Kawata, A; Kobayashi, J; Koide, R; Komori, T; Kuroda, M; Mizutani, T; Mochizuki, Y	1
Amagasa, M; Goto, J; Ishiura, H; Kihira, T; Kokubo, Y; Kuzuhara, S; Murayama, S; Naruse, H; Takahashi, Y; Tsuji, S; Yoshida, S	1
Dellefave, L; Deng, HX; Pascuzzi, RT; Rezania, K; Roos, RP; Siddique, N; Siddique, T; Yan, J	1
Jung, G; Link, J; Ludolph, AC; Reuter, A; Selzle, M; Völkel, H; Walk, T	1
Andersen, PM; Collinge, J; Fisher, EM; Hardiman, O; Highley, R; Ince, PG; Morrison, KE; Pall, HS; Parkinson, N; Shaw, PJ; Skibinski, G; Smith, MO	1
Deng, HX; He, X; Hentati, A; Hung, WY; Juneja, T; Mitsumoto, H; Ohnishi, A; Siddique, T; Tainer, JA; Zhao, Y	1
Bowling, AC; Ferrante, RJ; McKenna-Yasek, D; Mezey, E; O'Regan, J; Patterson, D; Rahmani, Z; Rosen, DR; Sapp, P; Usdin, TB	1
Araki, H; Fujii, J; Hirano, M; Nagai, Y; Okamoto, K; Sonobe, M; Taniguchi, N; Ueno, S	1
Brown, R; Haines, J; Horvitz, R; McKenna-Yasek, D; Robberecht, W; Rosen, D; Sapp, P; Theys, P; Viaene, MK	1
Miyazaki, S; Murai, Y; Ohnishi, A; Sakai, H; Ueno, S	1
Arciero, K; Badger, GJ; Betts, EF; Bromberg, MB; Carpenter, J; Forshew, D; Fries, TJ; Krusinski, PB; Nau, K; Tandan, R	1
Mandeli, J; Plaitakis, A; Smith, J; Yahr, MD	1
Pivovarova, VM	1

Trials

2 trial(s) available for valine and Amyotrophic Lateral Sclerosis

Article	Year
A controlled trial of amino acid therapy in amyotrophic lateral sclerosis: I. Clinical, functional, and maximum isometric torque data. Neurology, 1996, Volume: 47, Issue:5 Topics: Adult; Aged; Amino Acids; Amyotrophic Lateral Sclerosis; Analysis of Variance; Double-Blind Method; Female; Humans; Isoleucine; Leucine; Male; Middle Aged; Threonine; Valine	1996
Pilot trial of branched-chain aminoacids in amyotrophic lateral sclerosis. Lancet (London, England), 1988, May-07, Volume: 1, Issue:8593 Topics: Amino Acids, Branched-Chain; Amyotrophic Lateral Sclerosis; Clinical Trials as Topic; Drug Combinations; Female; Humans; Isoleucine; Leucine; Locomotion; Male; Middle Aged; Muscles; Neurologic Examination; Patient Compliance; Spinal Cord; Valine	1988

Other Studies

24 other study(ies) available for valine and Amyotrophic Lateral Sclerosis

Article	Year
Infantile SOD1 deficiency syndrome caused by a homozygous SOD1 variant with absence of enzyme activity. Brain : a journal of neurology, 2022, 04-29, Volume: 145, Issue:3 Topics: Amyotrophic Lateral Sclerosis; DNA, Complementary; Humans; Infant; Mutation; Superoxide Dismutase; Superoxide Dismutase-1; Syndrome; Valine	2022
A familial amyotrophic lateral sclerosis pedigree discordant for a novel p.Glu46Asp heterozygous OPTN variant and the p.Ala5Val heterozygous SOD1 missense mutation. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 2020, Volume: 75 Topics: Alanine; Amyotrophic Lateral Sclerosis; Aspartic Acid; Cell Cycle Proteins; Female; Genetic Testing; Genetic Variation; Glutamine; Heterozygote; High-Throughput Nucleotide Sequencing; Humans; Male; Membrane Transport Proteins; Middle Aged; Mutation, Missense; Pedigree; Superoxide Dismutase-1; Valine	2020
Identification of an A4V SOD1 mutation in a Chinese patient with amyotrophic lateral sclerosis without the A4V founder effect common in North America. Amyotrophic lateral sclerosis & frontotemporal degeneration, 2018, Volume: 19, Issue:5-6 Topics: Alanine; Amyotrophic Lateral Sclerosis; Asian People; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Superoxide Dismutase-1; Valine	2018
Multiple system involvement in a Japanese patient with a V31A mutation in the SOD1 gene. Amyotrophic lateral sclerosis & frontotemporal degeneration, 2014, Volume: 15, Issue:3-4 Topics: Adult; Aged; Alanine; Alkyl and Aryl Transferases; Amyotrophic Lateral Sclerosis; Asian People; Brain; DNA Mutational Analysis; Female; Humans; Magnetic Resonance Imaging; Middle Aged; Mutation; Superoxide Dismutase; Superoxide Dismutase-1; Valine	2014
Lack of evidence for an association between the V393A variant of COQ2 and amyotrophic lateral sclerosis in a Han Chinese population. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2015, Volume: 36, Issue:7 Topics: Adult; Aged; Alanine; Alkyl and Aryl Transferases; Amyotrophic Lateral Sclerosis; Asian People; Female; Gene Frequency; Genetic Association Studies; Genotype; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Valine	2015
TDP-43 M311V mutation in familial amyotrophic lateral sclerosis. Journal of neurology, neurosurgery, and psychiatry, 2009, Volume: 80, Issue:3 Topics: Adult; Aged; Alleles; Amino Acid Substitution; Amyotrophic Lateral Sclerosis; Belgium; Chromosome Aberrations; Codon; DNA Mutational Analysis; DNA-Binding Proteins; Exons; Female; Genes, Dominant; Humans; Male; Methionine; Middle Aged; Pedigree; Sequence Analysis, DNA; Superoxide Dismutase; Superoxide Dismutase-1; Valine	2009
SOD1 (A4V)-mediated ALS presenting with lower motor neuron facial diplegia and unilateral vocal cord paralysis. Muscle & nerve, 2009, Volume: 40, Issue:5 Topics: Aged; Alanine; Amyotrophic Lateral Sclerosis; Diagnosis, Differential; Facial Paralysis; Humans; Male; Superoxide Dismutase; Superoxide Dismutase-1; Valine; Vocal Cord Paralysis	2009
Structural and biophysical properties of metal-free pathogenic SOD1 mutants A4V and G93A. Archives of biochemistry and biophysics, 2009, Volume: 492, Issue:1-2 Topics: Alanine; Amino Acid Substitution; Amyotrophic Lateral Sclerosis; Copper; Crystallography, X-Ray; Genetic Variation; Glycine; Humans; Metals; Protein Binding; Protein Processing, Post-Translational; Protein Structure, Secondary; Superoxide Dismutase; Superoxide Dismutase-1; Valine	2009
Genetic contribution of FUS to frontotemporal lobar degeneration. Neurology, 2010, Feb-02, Volume: 74, Issue:5 Topics: Aged; Amino Acid Sequence; Amyotrophic Lateral Sclerosis; DNA Mutational Analysis; DNA-Binding Proteins; Female; Frontotemporal Lobar Degeneration; Glycine; Humans; Male; Methionine; Middle Aged; Mutation, Missense; RNA-Binding Protein FUS; Sequence Alignment; Sequence Deletion; Valine	2010
Study of 962 patients indicates progressive muscular atrophy is a form of ALS. Neurology, 2010, Jun-08, Volume: 74, Issue:23 Topics: Alanine; Amyotrophic Lateral Sclerosis; Humans; Muscular Atrophy, Spinal; Superoxide Dismutase; Superoxide Dismutase-1; Valine	2010
Increased levels of p70S6 phosphorylation in the G93A mouse model of Amyotrophic Lateral Sclerosis and in valine-exposed cortical neurons in culture. Experimental neurology, 2010, Volume: 226, Issue:1 Topics: Action Potentials; Amino Acids, Branched-Chain; Amyotrophic Lateral Sclerosis; Animals; Blotting, Western; Cell Survival; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Electrophysiology; Humans; Immunosuppressive Agents; Intracellular Signaling Peptides and Proteins; Mice; Mice, Transgenic; Neurons; Phosphorylation; Protein Serine-Threonine Kinases; Sirolimus; Sodium Channels; Superoxide Dismutase; Superoxide Dismutase-1; TOR Serine-Threonine Kinases; Valine	2010
Novel p.Ile151Val mutation in VCP in a patient of African American descent with sporadic ALS. Neurology, 2011, Sep-13, Volume: 77, Issue:11 Topics: Adenosine Triphosphatases; Aged; Amino Acid Sequence; Amyotrophic Lateral Sclerosis; Black or African American; Cell Cycle Proteins; Fatal Outcome; Female; Humans; Isoleucine; Molecular Sequence Data; Mutation; Valine; Valosin Containing Protein	2011
Mutant SOD1 forms ion channel: implications for ALS pathophysiology. Neurobiology of disease, 2012, Volume: 45, Issue:3 Topics: Alanine; Amyotrophic Lateral Sclerosis; Animals; Biophysical Phenomena; Biophysics; Calcium; Cell Line, Tumor; Electric Stimulation; Humans; Ion Channel Gating; Lipid Bilayers; Membrane Potentials; Membranes, Artificial; Mice; Microscopy, Atomic Force; Mutation; Neuroblastoma; Patch-Clamp Techniques; Protein Conformation; Superoxide Dismutase; Time Factors; Transfection; Valine	2012
Novel G37V mutation of SOD1 gene in autopsied patient with familial amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases, 2012, Volume: 13, Issue:6 Topics: Amyotrophic Lateral Sclerosis; Asian People; Autopsy; Glycine; Humans; Male; Middle Aged; Mutation, Missense; Neurofilament Proteins; Superoxide Dismutase; Superoxide Dismutase-1; Valine	2012
Mutational analysis of familial and sporadic amyotrophic lateral sclerosis with OPTN mutations in Japanese population. Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases, 2012, Volume: 13, Issue:6 Topics: Amyotrophic Lateral Sclerosis; Asian People; Cell Cycle Proteins; DNA Mutational Analysis; Family Health; Female; Genetic Predisposition to Disease; Humans; Male; Membrane Transport Proteins; Methionine; Middle Aged; Mutation; Transcription Factor TFIIIA; Valine	2012
A rare Cu/Zn superoxide dismutase mutation causing familial amyotrophic lateral sclerosis with variable age of onset, incomplete penetrance and a sensory neuropathy. Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases, 2003, Volume: 4, Issue:3 Topics: Adolescent; Adult; Age of Onset; Aged; Alanine; Amyotrophic Lateral Sclerosis; DNA Mutational Analysis; Exons; Family Health; Humans; Male; Mutation; Pedigree; Penetrance; Peripheral Nervous System Diseases; Polymorphism, Single Nucleotide; Reverse Transcriptase Polymerase Chain Reaction; Superoxide Dismutase; Valine	2003
Reduced reactivation rate in mutant CuZnSOD and progression rate of amyotrophic lateral sclerosis. European journal of neurology, 2004, Volume: 11, Issue:6 Topics: Alanine; Amyotrophic Lateral Sclerosis; Bacteria; Blotting, Western; Cloning, Molecular; Copper; Disease Progression; Gene Expression; Glycine; Humans; Isoenzymes; Mutagenesis, Site-Directed; Mutation; Recombinant Proteins; Sequence Analysis, Protein; Superoxide Dismutase; Temperature; Time Factors; Valine; Zinc	2004
ALS phenotypes with mutations in CHMP2B (charged multivesicular body protein 2B). Neurology, 2006, Sep-26, Volume: 67, Issue:6 Topics: Adaptor Proteins, Signal Transducing; Aged; alpha-Synuclein; Amyotrophic Lateral Sclerosis; Brain; DNA Mutational Analysis; Endosomal Sorting Complexes Required for Transport; Glial Fibrillary Acidic Protein; Glutamine; Histidine; Humans; Immunohistochemistry; Isoleucine; Male; Mutation; Nerve Tissue Proteins; Neurofilament Proteins; Phenotype; Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequestosome-1 Protein; Spinal Cord; tau Proteins; Ubiquitin; Valine	2006
Two novel SOD1 mutations in patients with familial amyotrophic lateral sclerosis. Human molecular genetics, 1995, Volume: 4, Issue:6 Topics: Amyotrophic Lateral Sclerosis; Base Sequence; Crystallography, X-Ray; DNA Primers; Humans; Leucine; Molecular Sequence Data; Mutation; Protein Conformation; Superoxide Dismutase; Valine	1995
A frequent ala 4 to val superoxide dismutase-1 mutation is associated with a rapidly progressive familial amyotrophic lateral sclerosis. Human molecular genetics, 1994, Volume: 3, Issue:6 Topics: Age of Onset; Alanine; Amino Acid Sequence; Amyotrophic Lateral Sclerosis; Animals; DNA Primers; Exons; Humans; In Situ Hybridization; Isoenzymes; Middle Aged; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; Sequence Homology, Amino Acid; Superoxide Dismutase; Survival Analysis; Valine	1994
A new variant Cu/Zn superoxide dismutase (Val7-->Glu) deduced from lymphocyte mRNA sequences from Japanese patients with familial amyotrophic lateral sclerosis. Biochemical and biophysical research communications, 1994, Oct-28, Volume: 204, Issue:2 Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Base Sequence; DNA Primers; Female; Glutamic Acid; Humans; Japan; Lymphocytes; Male; Middle Aged; Molecular Sequence Data; Mutation; RNA, Messenger; Superoxide Dismutase; Valine	1994
Cu/Zn superoxide dismutase activity in familial and sporadic amyotrophic lateral sclerosis. Journal of neurochemistry, 1994, Volume: 62, Issue:1 Topics: Adult; Amino Acid Sequence; Amyotrophic Lateral Sclerosis; Erythrocytes; Exons; Female; Humans; Isoenzymes; Leucine; Male; Nucleic Acid Conformation; Pedigree; Point Mutation; Polymorphism, Genetic; Superoxide Dismutase; Valine	1994
[Familial amyotrophic lateral sclerosis showing variable clinical courses with (Leu84-->Val) mutation of Cu/Zn superoxide dismutase]. Rinsho shinkeigaku = Clinical neurology, 1996, Volume: 36, Issue:3 Topics: Adult; Amyotrophic Lateral Sclerosis; Base Sequence; Family Health; Female; Humans; Leucine; Molecular Sequence Data; Pedigree; Point Mutation; Superoxide Dismutase; Valine	1996
[Amino acid metabolism in lateral amyotrophic sclerosis]. Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1971, Volume: 71, Issue:8 Topics: Adult; Aged; Amino Acids; Amyotrophic Lateral Sclerosis; Arginine; Female; Humans; Leucine; Male; Middle Aged; Serine; Valine	1971