valganciclovir and Dry-Eye-Syndromes

Cytomegalovirus (CMV) anterior uveitis and endotheliitis occurs among immunocompetent individuals and may manifest as Posner-Schlossman syndrome or Fuchs uveitis syndrome. The condition may first present following ophthalmic surgery, the use of a fluocinolone-sustained steroid drug delivery implant, or the use of topical prostaglandin analogues for the treatment of glaucoma. We report the first case of a non-human immunodeficiency virus-infected individual who presented with CMV anterior uveitis after the use of topical cyclosporine A 0.05% ophthalmic emulsion for the treatment of symptomatic dry eyes.

Topics: Administration, Ophthalmic; Aged; Antiviral Agents; Aqueous Humor; Cyclosporine; Cytomegalovirus; Cytomegalovirus Infections; DNA, Viral; Dry Eye Syndromes; Emulsions; Eye Infections, Viral; Female; Ganciclovir; Gene Dosage; Humans; Immunosuppressive Agents; Real-Time Polymerase Chain Reaction; Uveitis, Anterior; Valganciclovir