valganciclovir has been researched along with Blood-Loss--Surgical* in 1 studies
1 other study(ies) available for valganciclovir and Blood-Loss--Surgical
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Iron deficiency anemia and iron losses after renal transplantation.
Iron deficiency contributes to anemia after transplantation. The magnitude of iron loss from blood loss in the peri-transplantation period has not been quantified. We prospectively estimated phlebotomy and surgical losses over the first 12-weeks following transplantation in 39 consecutive renal transplant recipients on hemodialysis (HD), peritoneal dialysis (PD), or chronic kidney disease (CKD). At transplant, ferritin levels were <200 ng/ml in 51% of the patients, and iron saturation was =20% in 44%. CKD patients more commonly had ferritin levels <200 ng/ml than either HD or PD patients (100% vs. 21% vs. 67%, P < 0.0002, respectively). Blood loss was similar among HD, PD and CKD patients (833 +/- 194 vs. 861 +/- 324 vs. 755 +/- 79 ml respectively, P = NS), and no difference between deceased and living donor transplant recipients (881 +/- 291 vs. 788 +/- 162 ml, P = 0.33). Based on baseline hemoglobin (Hgb) of 11.8 g/dl, we estimated that an additional 330 mg of iron was needed to normalize hemoglobin to 13 g/dl, and 605 mg to increase hemoglobin to 14 g/dl. Blood and iron losses over the first 12 weeks post-transplant are substantial and may warrant early administration of intravenous iron. Topics: Adult; Aged; Anemia, Iron-Deficiency; Antiviral Agents; Blood Loss, Surgical; Female; Ferritins; Ganciclovir; Hemoglobins; Humans; Immunosuppression Therapy; Infusions, Intravenous; Iron; Kidney Function Tests; Kidney Transplantation; Male; Middle Aged; Prospective Studies; Valganciclovir; Young Adult | 2009 |