Page last updated: 2024-09-03

valdecoxib and Neoplasms

valdecoxib has been researched along with Neoplasms in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's4 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Casini, A; Lehtonen, JM; Parkkila, S; Scozzafava, A; Supuran, CT; Vullo, D1
Innocenti, A; Knaus, EE; Scozzafava, A; Supuran, CT1
Arellano, ML; Boggon, TJ; Brat, DJ; Chen, GZ; Chen, J; Chen, PR; DeBerardinis, RJ; Elf, S; Fan, J; Gu, TL; He, C; Hitosugi, T; Hurwitz, SJ; Ji, Q; Jiang, L; Kang, HB; Kang, S; Khoury, HJ; Khuri, FR; Lee, BH; Lei, Q; Li, Y; Lin, R; Lonial, S; Mao, H; Mitsche, M; Seo, JH; Shan, C; Sudderth, J; Tucker, M; Wang, D; Wu, S; Xie, J; Ye, K; Zhang, L; Zhang, S; Zhou, L1
Cheng, C; Jia, Y; Jin, X; Liu, Y; Wang, G; Yao, L; Zhang, J; Zhou, F1
Bartzatt, R1
Vanchieri, C1

Reviews

1 review(s) available for valdecoxib and Neoplasms

ArticleYear
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
    Nature cell biology, 2015, Volume: 17, Issue:11

    Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; Oxidative Stress; Pentose Phosphate Pathway; Phosphogluconate Dehydrogenase; Protein Serine-Threonine Kinases; Ribulosephosphates; Signal Transduction

2015

Other Studies

5 other study(ies) available for valdecoxib and Neoplasms

ArticleYear
Carbonic anhydrase inhibitors. Inhibition of cytosolic isozyme XIII with aromatic and heterocyclic sulfonamides: a novel target for the drug design.
    Bioorganic & medicinal chemistry letters, 2004, Jul-16, Volume: 14, Issue:14

    Topics: Amino Acid Sequence; Animals; Carbonic Anhydrase Inhibitors; Cytosol; Drug Design; Humans; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Molecular Sequence Data; Neoplasms; Rats; Structure-Activity Relationship; Sulfonamides

2004
Phenylethynylbenzenesulfonamide regioisomers strongly and selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic isoforms I and II.
    Bioorganic & medicinal chemistry letters, 2011, Oct-01, Volume: 21, Issue:19

    Topics: Antigens, Neoplasm; Carbonic Anhydrase I; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Cytosol; Drug Screening Assays, Antitumor; Humans; Isoenzymes; Molecular Targeted Therapy; Neoplasms; Stereoisomerism; Structure-Activity Relationship; Sulfonamides

2011
Simultaneous determination of parecoxib and its main metabolites valdecoxib and hydroxylated valdecoxib in mouse plasma with a sensitive LC-MS/MS method to elucidate the decreased drug metabolism of tumor bearing mice.
    Journal of pharmaceutical and biomedical analysis, 2018, Sep-05, Volume: 158

    Topics: Animals; Cell Line, Tumor; Chromatography, High Pressure Liquid; Cyclooxygenase 2 Inhibitors; Cytochrome P-450 Enzyme System; Drug Monitoring; Female; Humans; Isoxazoles; Mice; Mice, Inbred BALB C; Neoplasms; Oxazoles; Prodrugs; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Sulfonamides; Tandem Mass Spectrometry; Xenograft Model Antitumor Assays

2018
Drug analogs of COX-2 selective inhibitors lumiracoxib and valdecoxib derived from in silico search and optimization.
    Anti-inflammatory & anti-allergy agents in medicinal chemistry, 2014, Volume: 13, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Computer Simulation; Cyclooxygenase 2 Inhibitors; Diclofenac; Drug Design; Humans; Isoxazoles; Models, Molecular; Neoplasms; Pain; Sulfonamides

2014
Researchers plan to continue to study COX-2 inhibitors in cancer treatment and prevention.
    Journal of the National Cancer Institute, 2005, Apr-20, Volume: 97, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Antineoplastic Agents; Celecoxib; Clinical Trials as Topic; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Humans; Incidence; Isoxazoles; Lactones; Membrane Proteins; Meta-Analysis as Topic; Myocardial Infarction; Neoplasms; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Sulfonamides; Sulfones; United States; United States Food and Drug Administration

2005