vadimezan has been researched along with Necrosis in 21 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 8 (38.10) | 18.2507 |
2000's | 11 (52.38) | 29.6817 |
2010's | 2 (9.52) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Ching, LM; Henare, K; Kieda, C; Palmer, BD; Reddy, C; Sutherland, R; Wang, LC; Woon, ST | 1 |
Aghaei, M; Downey, CM; Jirik, FR; Schwendener, RA | 1 |
de Witte, P; Lerut, E; Marysael, T; Ni, Y | 1 |
Baguley, BC; Ching, LM; Kestell, P; Zhao, L | 1 |
Baguley, BC; Ching, LM | 1 |
Bellnier, DA; Camacho, SH; Cheney, RT; Gollnick, SO; Greco, WR | 1 |
Thorpe, PE | 1 |
Baguley, BC; Ching, LM; Drummond, CJ; Kieda, C; Reddy, CB; Schooltink, MA; Woon, ST | 1 |
Griffiths, JR; Kelland, LR; Kestell, P; Ludwig, C; McIntyre, DJ; McPhail, LD; Robinson, SP | 1 |
Albelda, SM; Blouin, A; Cheng, G; Ching, LM; Jassar, A; Kapoor, V; LaRosa, DF; Sun, J; Wallace, A | 1 |
De Witte, PA; Ni, Y; Van de Putte, M | 1 |
Bibby, MC; Double, JA; Laws, AL; Matthew, AM | 1 |
Baguley, BC; Ching, LM; Joseph, WR; Zhuang, L | 1 |
Baguley, BC; Gavin, JB; Wilson, WR; Zwi, LJ | 2 |
Baguley, BC; Cole, G; Li, Z; Thomsen, LL | 1 |
Baguley, BC; Li, Z; Thomsen, LL; Veszelovszky, E | 1 |
Baguley, BC; Ching, LM; Goldsmith, D; Joseph, WR; Körner, H; Sedgwick, JD | 1 |
Baguley, BC | 1 |
Lepler, S; Mercer, E; Rojiani, AM; Siemann, DW | 1 |
Baguley, BC; Ching, LM; Joseph, WR | 1 |
2 review(s) available for vadimezan and Necrosis
Article | Year |
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Vascular targeting agents as cancer therapeutics.
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Cell Division; Clinical Trials as Topic; Diphosphates; Genetic Therapy; Humans; Hypoxia; Immunotoxins; Ligands; Models, Biological; Necrosis; Neoplasms; Organophosphorus Compounds; Peptides; Radioimmunotherapy; Stilbenes; Time Factors; Up-Regulation; Xanthones | 2004 |
Small-molecule cytokine inducers causing tumor necrosis.
Topics: 5-Hydroxytryptophan; Animals; Antineoplastic Agents; Capillary Permeability; Cytokines; Endothelium, Vascular; Flavonoids; Humans; Interferon-alpha; Mice; Microcirculation; Necrosis; Neoplasms; NF-kappa B; Nitric Oxide; Tumor Necrosis Factor-alpha; Xanthenes; Xanthones | 2001 |
19 other study(ies) available for vadimezan and Necrosis
Article | Year |
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Synthesis and biological activity of azido analogues of 5,6-dimethylxanthenone-4-acetic acid for use in photoaffinity labeling.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Azides; Cells, Cultured; Colonic Neoplasms; Hemorrhage; Mice; Mice, Inbred C57BL; Necrosis; NF-kappa B; Photoaffinity Labels; Protein Binding; Spleen; Structure-Activity Relationship; Transplantation, Heterologous; Tumor Necrosis Factor-alpha; Xanthones | 2007 |
DMXAA causes tumor site-specific vascular disruption in murine non-small cell lung cancer, and like the endogenous non-canonical cyclic dinucleotide STING agonist, 2'3'-cGAMP, induces M2 macrophage repolarization.
Topics: Adenocarcinoma; Animals; Carcinoma, Non-Small-Cell Lung; Cell Membrane Permeability; Cell Polarity; Clodronic Acid; Humans; Inflammation; Liposomes; Lung Neoplasms; Macrophages; Male; Membrane Proteins; Mice, Transgenic; Necrosis; Neovascularization, Pathologic; Nucleotides, Cyclic; Phenotype; ras Proteins; Subcutaneous Tissue; Tumor Suppressor Protein p53; Xanthones; Xenograft Model Antitumor Assays | 2014 |
Influence of the vascular damaging agents DMXAA and ZD6126 on hypericin distribution and accumulation in RIF-1 tumors.
Topics: Animals; Anthracenes; Antineoplastic Agents; Cell Line, Tumor; Mice; Mice, Inbred C3H; Necrosis; Neoplasms; Neovascularization, Pathologic; Organophosphorus Compounds; Perylene; Telomere-Binding Proteins; Xanthones | 2011 |
The antitumour activity of 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in TNF receptor-1 knockout mice.
Topics: Animals; Antigens, CD; Antineoplastic Agents; Colonic Neoplasms; Dose-Response Relationship, Drug; Mice; Mice, Inbred C57BL; Mice, Knockout; Necrosis; Neoplasm Transplantation; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Serotonin; Time Factors; Tumor Necrosis Factor-alpha; Xanthenes; Xanthones | 2002 |
DMXAA: an antivascular agent with multiple host responses.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Hydroxyindoleacetic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; Models, Chemical; Necrosis; Neoplasm Transplantation; Neovascularization, Pathologic; Nitric Oxide; Receptors, Tumor Necrosis Factor; Serotonin; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Xanthenes; Xanthones | 2002 |
Treatment with the tumor necrosis factor-alpha-inducing drug 5,6-dimethylxanthenone-4-acetic acid enhances the antitumor activity of the photodynamic therapy of RIF-1 mouse tumors.
Topics: Animals; Antibodies, Monoclonal; Cell Line, Tumor; Dihematoporphyrin Ether; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Female; Fibrosarcoma; Mice; Mice, Inbred C3H; Necrosis; Neoplasms, Experimental; Photochemotherapy; Tumor Necrosis Factor-alpha; Xanthones | 2003 |
A comparison of the ability of DMXAA and xanthenone analogues to activate NF-kappaB in murine and human cell lines.
Topics: Animals; Antineoplastic Agents; Biological Assay; Cell Line, Tumor; Colonic Neoplasms; Dose-Response Relationship, Drug; Endothelial Cells; Humans; Lymphoma, B-Cell; Mice; Necrosis; NF-kappa B; Structure-Activity Relationship; Xanthenes; Xanthones | 2005 |
Rat tumor response to the vascular-disrupting agent 5,6-dimethylxanthenone-4-acetic acid as measured by dynamic contrast-enhanced magnetic resonance imaging, plasma 5-hydroxyindoleacetic acid levels, and tumor necrosis.
Topics: Angiogenesis Inhibitors; Animals; Area Under Curve; Biomarkers; Capillary Permeability; Cell Line, Tumor; Contrast Media; Dose-Response Relationship, Drug; Female; Gadolinium DTPA; Indoles; Magnetic Resonance Imaging; Necrosis; Neoplasm Transplantation; Neovascularization, Pathologic; Pituitary Neoplasms; Prolactinoma; Rats; Rats, Inbred WF; Subcutaneous Tissue; Xanthones | 2006 |
The vascular disrupting agent, DMXAA, directly activates dendritic cells through a MyD88-independent mechanism and generates antitumor cytotoxic T lymphocytes.
Topics: Animals; Antineoplastic Agents; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Chickens; Cytokines; Dendritic Cells; Mice; Mice, Inbred C57BL; Myeloid Differentiation Factor 88; Necrosis; Neoplasm Transplantation; Ovalbumin; T-Lymphocytes, Cytotoxic; Xanthones | 2007 |
Exploration of the mechanism underlying the tumor necrosis avidity of hypericin.
Topics: Animals; Anthracenes; Carbocyanines; Female; Fibrosarcoma; Lipoproteins; Mice; Mice, Inbred C3H; Necrosis; Perylene; Sarcoma, Experimental; Xanthones | 2008 |
Preclinical in vitro and in vivo activity of 5,6-dimethylxanthenone-4-acetic acid.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Survival; Colonic Neoplasms; Hemorrhage; Humans; Lung Neoplasms; Mice; Mice, Inbred Strains; Mice, Nude; Necrosis; Species Specificity; Tumor Cells, Cultured; Xanthenes; Xanthones | 1995 |
Interaction between endotoxin and the antitumour agent 5,6-dimethylxanthenone-4-acetic acid in the induction of tumour necrosis factor and haemorrhagic necrosis of colon 38 tumours.
Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Synergism; Endotoxins; Lipopolysaccharides; Mice; Necrosis; Tumor Necrosis Factor-alpha; Xanthenes; Xanthones | 1994 |
The morphological effects of the anti-tumor agents flavone acetic acid and 5,6-dimethyl xanthenone acetic acid on the colon 38 mouse tumor.
Topics: Adenocarcinoma; Adenosine Triphosphate; Animals; Apoptosis; Colonic Neoplasms; Flavonoids; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Microscopy, Electron; Necrosis; Phosphocreatine; Xanthenes; Xanthones | 1994 |
Serotonin involvement in the antitumour and host effects of flavone-8-acetic acid and 5,6-dimethylxanthenone-4-acetic acid.
Topics: Animals; Antineoplastic Agents; Colonic Neoplasms; Cyproheptadine; Flavonoids; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Necrosis; Nitrates; Nitric Oxide; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tumor Necrosis Factor-alpha; Xanthenes; Xanthones | 1993 |
Flavone acetic acid and 5,6-dimethylxanthenone-4-acetic acid: relationship between plasma nitrate elevation and the induction of tumour necrosis.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Arginine; Canavanine; Colonic Neoplasms; Flavonoids; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Necrosis; Nitrates; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Xanthenes; Xanthones | 1993 |
Induction of intratumoral tumor necrosis factor (TNF) synthesis and hemorrhagic necrosis by 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in TNF knockout mice.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; Hemorrhage; Mice; Mice, Inbred C57BL; Mice, Knockout; Necrosis; Neoplasm Proteins; Neovascularization, Pathologic; RNA, Messenger; RNA, Neoplasm; Tumor Necrosis Factor-alpha; Xanthenes; Xanthones | 1999 |
Vascular targeting agents enhance chemotherapeutic agent activities in solid tumor therapy.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Blood Vessels; Cisplatin; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Synergism; Female; Humans; Mice; Mice, Inbred C3H; Mice, Nude; Necrosis; Neovascularization, Pathologic; Sarcoma, Experimental; Stilbenes; Tumor Cells, Cultured; Xanthenes; Xanthones | 2002 |
Antitumour responses to flavone-8-acetic acid and 5,6-dimethylxanthenone-4-acetic acid in immune deficient mice.
Topics: Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; Flavonoids; Mice; Mice, Inbred Strains; Mice, Nude; Necrosis; T-Lymphocytes; Thymectomy; Xanthenes; Xanthones | 1992 |
Necrosis in non-tumour tissues caused by flavone acetic acid and 5,6-dimethyl xanthenone acetic acid.
Topics: Animals; Antineoplastic Agents; Endometrium; Female; Flavonoids; Lymphoid Tissue; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Necrosis; Thrombosis; Xanthenes; Xanthones | 1990 |