Page last updated: 2024-09-03

vadimezan and Adenocarcinoma

vadimezan has been researched along with Adenocarcinoma in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (26.67)18.2507
2000's8 (53.33)29.6817
2010's3 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ching, LM; Henare, K; Kieda, C; Palmer, BD; Reddy, C; Sutherland, R; Wang, LC; Woon, ST1
Aghaei, M; Downey, CM; Jirik, FR; Schwendener, RA1
Batubara, A; Carolan, VA; Clench, MR; Loadman, PM; Shnyder, SD; Sutton, C1
Barbera, M; Brindle, KM; Caputo, A; Carrara, M; Gobbi, S; Hu, DE; Kettunen, MI1
Hida, T; Hirashima, T; Horai, T; Horio, Y; Kobayashi, K; Nishio, M; Shi, MM; Tamiya, M; Tanii, H; Yamamoto, N1
Baguley, BC; Ching, LM; Newth, AL; Schooltink, MA; Woon, ST; Zwain, S1
Baguley, BC; Ching, LM; Kelland, LR; Kestell, P; Zhao, L1
Bellnier, DA; Cheney, RT; Maiery, PG; Mazurchuk, R; Seshadri, M; Spernyak, JA1
Barbera, M; Bisi, A; Caputo, A; Carrara, M; Gobbi, S; Rampa, A; Zampiron, A1
Baguley, BC; Gavin, JB; Wilson, WR; Zwi, LJ1
Baguley, BC; Li, Z; Thomsen, LL; Veszelovszky, E1
Baguley, BC; Ching, LM; Goldsmith, D; Joseph, WR; Körner, H; Sedgwick, JD1
Beauregard, DA; Brindle, KM; Hill, SA; Pedley, RB1
Baguley, BC; Cao, Z; Ching, LM; Jameson, MB; Kieda, C; Zwain, S1
Baguley, BC; Thomsen, LL; Wilson, WR1

Trials

2 trial(s) available for vadimezan and Adenocarcinoma

ArticleYear
Phase I study of intravenous ASA404 (vadimezan) administered in combination with paclitaxel and carboplatin in Japanese patients with non-small cell lung cancer.
    Cancer science, 2011, Volume: 102, Issue:4

    Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Asian People; Biomarkers, Tumor; Carboplatin; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Female; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Staging; Paclitaxel; Remission Induction; Survival Rate; Tissue Distribution; Treatment Outcome; Xanthones

2011
Induction of endothelial cell apoptosis by the antivascular agent 5,6-Dimethylxanthenone-4-acetic acid.
    British journal of cancer, 2002, Jun-17, Volume: 86, Issue:12

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Blotting, Northern; Breast Neoplasms; Cells, Cultured; Chemokine CXCL10; Chemokines, CXC; Colonic Neoplasms; Endothelium, Vascular; Female; Humans; Interferons; Mice; Mice, Inbred C57BL; Ovarian Neoplasms; RNA, Messenger; Tumor Necrosis Factor-alpha; Xanthenes; Xanthones

2002

Other Studies

13 other study(ies) available for vadimezan and Adenocarcinoma

ArticleYear
Synthesis and biological activity of azido analogues of 5,6-dimethylxanthenone-4-acetic acid for use in photoaffinity labeling.
    Journal of medicinal chemistry, 2007, Aug-09, Volume: 50, Issue:16

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Azides; Cells, Cultured; Colonic Neoplasms; Hemorrhage; Mice; Mice, Inbred C57BL; Necrosis; NF-kappa B; Photoaffinity Labels; Protein Binding; Spleen; Structure-Activity Relationship; Transplantation, Heterologous; Tumor Necrosis Factor-alpha; Xanthones

2007
DMXAA causes tumor site-specific vascular disruption in murine non-small cell lung cancer, and like the endogenous non-canonical cyclic dinucleotide STING agonist, 2'3'-cGAMP, induces M2 macrophage repolarization.
    PloS one, 2014, Volume: 9, Issue:6

    Topics: Adenocarcinoma; Animals; Carcinoma, Non-Small-Cell Lung; Cell Membrane Permeability; Cell Polarity; Clodronic Acid; Humans; Inflammation; Liposomes; Lung Neoplasms; Macrophages; Male; Membrane Proteins; Mice, Transgenic; Necrosis; Neovascularization, Pathologic; Nucleotides, Cyclic; Phenotype; ras Proteins; Subcutaneous Tissue; Tumor Suppressor Protein p53; Xanthones; Xenograft Model Antitumor Assays

2014
Thin-layer chromatography/matrix-assisted laser desorption/ionisation mass spectrometry and matrix-assisted laser desorption/ionisation mass spectrometry imaging for the analysis of phospholipids in LS174T colorectal adenocarcinoma xenografts treated with
    Rapid communications in mass spectrometry : RCM, 2015, Jul-30, Volume: 29, Issue:14

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Chromatography, Thin Layer; Colon; Colorectal Neoplasms; Male; Mice; Mice, Nude; Phospholipids; Rectum; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Xanthones

2015
Immune-modulating and anti-vascular activities of two xanthenone acetic acid analogues: A comparative study to DMXAA.
    International journal of oncology, 2009, Volume: 34, Issue:1

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Cell Proliferation; Cells, Cultured; Endothelium, Vascular; Female; Flow Cytometry; Humans; I-kappa B Kinase; Immunity, Cellular; Leukemia; Magnetic Resonance Imaging; Mice; Mice, Inbred CBA; Microcirculation; NF-kappa B; Ovarian Neoplasms; Phosphorylation; Sarcoma, Experimental; Tumor Necrosis Factor-alpha; Umbilical Veins; Xanthones

2009
NF-kappa B activation in vivo in both host and tumour cells by the antivascular agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA).
    European journal of cancer (Oxford, England : 1990), 2003, Volume: 39, Issue:8

    Topics: Adenocarcinoma; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; NF-kappa B; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Tumor Cells, Cultured; Xanthenes; Xanthones

2003
Mechanisms of tumor vascular shutdown induced by 5,6-dimethylxanthenone-4-acetic acid (DMXAA): Increased tumor vascular permeability.
    International journal of cancer, 2005, Aug-20, Volume: 116, Issue:2

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Capillary Permeability; Colonic Neoplasms; Female; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neoplasms, Experimental; Neovascularization, Pathologic; Receptors, Tumor Necrosis Factor, Type I; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Xanthones

2005
Visualizing the acute effects of vascular-targeted therapy in vivo using intravital microscopy and magnetic resonance imaging: correlation with endothelial apoptosis, cytokine induction, and treatment outcome.
    Neoplasia (New York, N.Y.), 2007, Volume: 9, Issue:2

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Capillary Permeability; Colonic Neoplasms; Contrast Media; Drug Delivery Systems; Drug Screening Assays, Antitumor; Endothelium, Vascular; Female; Hemorrhage; Magnetic Resonance Imaging; Mice; Mice, Inbred BALB C; Microscopy; Neoplasm Proteins; Neoplasm Transplantation; Pentetic Acid; Polylysine; RNA, Messenger; RNA, Neoplasm; Skin Window Technique; Transplantation, Heterotopic; Transplantation, Isogeneic; Tumor Necrosis Factor-alpha; Xanthones

2007
The ability of coumarin-, flavanon- and flavonol-analogues of flavone acetic acid to stimulate human monocytes.
    Oncology reports, 2008, Volume: 19, Issue:1

    Topics: Adenocarcinoma; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Coumarins; Drug Screening Assays, Antitumor; Female; Flavonoids; Humans; Lipopolysaccharides; Monocytes; Nitric Oxide; Ovarian Neoplasms; Tumor Necrosis Factor-alpha; Xanthones

2008
The morphological effects of the anti-tumor agents flavone acetic acid and 5,6-dimethyl xanthenone acetic acid on the colon 38 mouse tumor.
    Pathology, 1994, Volume: 26, Issue:2

    Topics: Adenocarcinoma; Adenosine Triphosphate; Animals; Apoptosis; Colonic Neoplasms; Flavonoids; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Microscopy, Electron; Necrosis; Phosphocreatine; Xanthenes; Xanthones

1994
Flavone acetic acid and 5,6-dimethylxanthenone-4-acetic acid: relationship between plasma nitrate elevation and the induction of tumour necrosis.
    European journal of cancer (Oxford, England : 1990), 1993, Volume: 29A, Issue:3

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Arginine; Canavanine; Colonic Neoplasms; Flavonoids; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Necrosis; Nitrates; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Xanthenes; Xanthones

1993
Induction of intratumoral tumor necrosis factor (TNF) synthesis and hemorrhagic necrosis by 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in TNF knockout mice.
    Cancer research, 1999, Jul-15, Volume: 59, Issue:14

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; Hemorrhage; Mice; Mice, Inbred C57BL; Mice, Knockout; Necrosis; Neoplasm Proteins; Neovascularization, Pathologic; RNA, Messenger; RNA, Neoplasm; Tumor Necrosis Factor-alpha; Xanthenes; Xanthones

1999
Differential sensitivity of two adenocarcinoma xenografts to the anti-vascular drugs combretastatin A4 phosphate and 5,6-dimethylxanthenone-4-acetic acid, assessed using MRI and MRS.
    NMR in biomedicine, 2002, Volume: 15, Issue:2

    Topics: Adenocarcinoma; Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Contrast Media; Gadolinium DTPA; Humans; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Mice; Mice, SCID; Stilbenes; Transplantation, Heterologous; Xanthenes; Xanthones

2002
Nitric oxide: its production in host-cell-infiltrated EMT6 spheroids and its role in tumour cell killing by flavone-8-acetic acid and 5,6-dimethylxanthenone-4-acetic acid.
    Cancer chemotherapy and pharmacology, 1992, Volume: 31, Issue:2

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Flavonoids; Mammary Neoplasms, Experimental; Nitric Oxide; Tumor Cells, Cultured; Tumor Stem Cell Assay; Xanthenes; Xanthones

1992