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usnic acid and Neoplasms

usnic acid has been researched along with Neoplasms in 8 studies

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
"Chronic diseases such as cancer, diabetes, neurodegenerative and cardiovascular diseases are characterized by an enhanced state of oxidative stress, which may result from the overproduction of reactive species and/or a decrease in antioxidant defenses."2.50Antioxidant activity and mechanisms of action of natural compounds isolated from lichens: a systematic review. ( Almeida, JR; Araújo, AA; Gelain, DP; Moreira, JC; Oliveira, AP; Oliveira, RC; Quintans, JS; Quintans-Junior, LJ; Santos, MR; Serafini, MR; White, PA, 2014)
"Usnic acid is a secondary metabolite isolated predominately from lichen species and has been shown to exhibit antiproliferative properties, however its application is limited by poor drug-like properties and low specificity."1.91Divergent reactivity of usnic acid and evaluation of its derivatives for antiproliferative activity against cancer cells. ( Gardiner, MG; Gimła, M; Gunawan, GA; Herman-Antosiewicz, A; Reekie, TA, 2023)
"Since cancer is a continuously increasing concern for the general population, more efficient treatment alternatives ought to be developed."1.91Usnic Acid-Loaded Magnetite Nanoparticles-A Comparative Study between Synthesis Methods. ( Andronescu, E; Bîrcă, AC; Chircov, C; Dănciulescu, LA; Neacșu, IA; Oprea, OC; Trușcă, RD, 2023)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's5 (62.50)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Lin, R1
Elf, S1
Shan, C1
Kang, HB1
Ji, Q1
Zhou, L1
Hitosugi, T1
Zhang, L1
Zhang, S1
Seo, JH1
Xie, J1
Tucker, M1
Gu, TL1
Sudderth, J1
Jiang, L1
Mitsche, M1
DeBerardinis, RJ1
Wu, S1
Li, Y1
Mao, H1
Chen, PR1
Wang, D1
Chen, GZ1
Hurwitz, SJ1
Lonial, S1
Arellano, ML1
Khoury, HJ1
Khuri, FR1
Lee, BH1
Lei, Q1
Brat, DJ1
Ye, K1
Boggon, TJ1
He, C1
Kang, S1
Fan, J1
Chen, J1
Gunawan, GA1
Gimła, M1
Gardiner, MG1
Herman-Antosiewicz, A1
Reekie, TA1
Chircov, C1
Bîrcă, AC1
Dănciulescu, LA1
Neacșu, IA1
Oprea, OC1
Trușcă, RD1
Andronescu, E1
White, PA1
Oliveira, RC1
Oliveira, AP1
Serafini, MR1
Araújo, AA1
Gelain, DP1
Moreira, JC1
Almeida, JR1
Quintans, JS1
Quintans-Junior, LJ1
Santos, MR1
Burlando, B1
Ranzato, E1
Volante, A1
Appendino, G1
Pollastro, F1
Verotta, L1
Bačkorová, M1
Bačkor, M2
Mikeš, J1
Jendželovský, R1
Fedoročko, P1
Ivanova, V1
Dahse, HM1
Graefe, U1
Bessadottir, M1
Egilsson, M1
Einarsdottir, E1
Magnusdottir, IH1
Ogmundsdottir, MH1
Omarsdottir, S1
Ogmundsdottir, HM1

Reviews

2 reviews available for usnic acid and Neoplasms

ArticleYear
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
    Nature cell biology, 2015, Volume: 17, Issue:11

    Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms;

2015
Antioxidant activity and mechanisms of action of natural compounds isolated from lichens: a systematic review.
    Molecules (Basel, Switzerland), 2014, Sep-12, Volume: 19, Issue:9

    Topics: Antioxidant Response Elements; Antioxidants; Benzofurans; Biphenyl Compounds; Free Radical Scavenger

2014

Other Studies

6 other studies available for usnic acid and Neoplasms

ArticleYear
Divergent reactivity of usnic acid and evaluation of its derivatives for antiproliferative activity against cancer cells.
    Bioorganic & medicinal chemistry, 2023, 02-01, Volume: 79

    Topics: Benzofurans; HeLa Cells; Humans; Lichens; Neoplasms

2023
Usnic Acid-Loaded Magnetite Nanoparticles-A Comparative Study between Synthesis Methods.
    Molecules (Basel, Switzerland), 2023, Jul-04, Volume: 28, Issue:13

    Topics: Humans; Magnetite Nanoparticles; Microscopy, Electron, Scanning; Neoplasms; Spectroscopy, Fourier Tr

2023
Antiproliferative effects on tumour cells and promotion of keratinocyte wound healing by different lichen compounds.
    Planta medica, 2009, Volume: 75, Issue:6

    Topics: Antineoplastic Agents, Phytogenic; Benzoates; Benzofurans; Cell Line, Tumor; Cell Proliferation; Fem

2009
Variable responses of different human cancer cells to the lichen compounds parietin, atranorin, usnic acid and gyrophoric acid.
    Toxicology in vitro : an international journal published in association with BIBRA, 2011, Volume: 25, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Benzoates; Benzofurans; Cell Adhesion; Cell Line, Tumor; Cell Nucl

2011
Molecular structural studies of lichen substances with antimicrobial, antiproliferative, and cytotoxic effects from Parmelia subrudecta.
    Preparative biochemistry & biotechnology, 2010, Volume: 40, Issue:4

    Topics: Anti-Infective Agents; Antineoplastic Agents; Bacteria; Bacterial Infections; Benzofurans; Cell Line

2010
Proton-shuttling lichen compound usnic acid affects mitochondrial and lysosomal function in cancer cells.
    PloS one, 2012, Volume: 7, Issue:12

    Topics: Adenosine Triphosphate; Adenylate Kinase; Benzofurans; Drug Screening Assays, Antitumor; Enzyme Acti

2012