ursolic acid has been researched along with Lung Neoplasms in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (5.26) | 29.6817 |
| 2010's | 14 (73.68) | 24.3611 |
| 2020's | 4 (21.05) | 2.80 |
| Authors | Studies |
|---|---|
| Ayres, M; Bartholomeusz, GA; Gandhi, V; Mendes, VIS; Salvador, JAR | 1 |
| Kornel, A; Nadile, M; Tsiani, E | 1 |
| Bao, C; Cai, S; Chen, Q; Kong, J; Liu, D; Lu, H; Luo, J; Wu, C | 1 |
| Bi, C; Duan, Y; Gou, W; Hou, W; Li, Y; Luo, N; Ning, H; Wei, H; Wu, H; Yu, X | 1 |
| Chen, ZY; Gao, SH; Hu, Q; Wang, M; Wu, R; Yu, H; Zhang, YF; Zhou, GB | 1 |
| Fan, L; Jiang, K; Li, T; Shao, J; Zhao, R; Zheng, G | 1 |
| Jiang, ZS; Ruan, JS; Sun, H; Wang, L; Wang, SM; Yang, L; Zhou, H | 1 |
| Chou, CH; Jhan, YL; Tsai, SJ; Wang, CM; Yeh, KL | 1 |
| Chen, L; Chen, Y; Cheng, X; Dai, H; Hu, X; Ji, X; Li, C; Ma, L; Shan, Y; Tao, Z; Wang, Y; Yang, K; Yin, W; Zhang, Z; Zhou, J; Zhu, B | 1 |
| Bao, W; Guo, L; Li, X; Liu, K; Miao, L; Xi, T; Yang, J; Zhao, W | 1 |
| Chen, Y; Hann, SS; Li, L; Tang, Q; Wu, J; Wu, W; Yang, L; Yang, X; Zhao, S; Zheng, F | 1 |
| Baek, NI; Choi, KY; Harikishore, A; Jung, HY; Kim, KT; Kim, SH; Kim, YS; Lee, J; Lyu, HN; Oh, E; Ryu, HG; Shin, J; Yoon, HS | 1 |
| Gao, JL; He, BC; He, TC; Huang, EY; Ji, X; Jiang, W; Lv, GY; Shou, QY; Shui, YM | 1 |
| Kim, HJ; Kim, SH; Lee, I; Lee, J; Sohn, EJ; Won, G; Yoon, SW | 1 |
| Chen, Q; Chen, WR; Li, Y; Xing, D | 1 |
| Huang, CY; Lin, CY; Tsai, CW; Yin, MC | 1 |
| Chang, CD; Liao, MH; Lin, PY; Shih, WL; Wu, HY; Yu, FL | 1 |
| Jia, X; Jin, P; Liu, W; Shu, L; Song, J; Sun, H; Sun, M; Tan, X; Yu, S | 1 |
| Hsu, YL; Kuo, PL; Lin, CC | 1 |
1 review(s) available for ursolic acid and Lung Neoplasms
| Article | Year |
|---|---|
Evidence of the Beneficial Effects of Ursolic Acid against Lung Cancer.
Topics: Animals; Cell Proliferation; Lung Neoplasms; Paclitaxel; Triterpenes; Ursolic Acid | 2022 |
18 other study(ies) available for ursolic acid and Lung Neoplasms
| Article | Year |
|---|---|
Synthesis and cytotoxic activity of novel A-ring cleaved ursolic acid derivatives in human non-small cell lung cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Autophagy; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Chemistry Techniques, Synthetic; DNA; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Protein Biosynthesis; RNA; Triterpenes; Ursolic Acid | 2016 |
The miRNA-149-5p/MyD88 axis is responsible for ursolic acid-mediated attenuation of the stemness and chemoresistance of non-small cell lung cancer cells.
Topics: A549 Cells; Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mice, Inbred BALB C; Mice, Nude; MicroRNAs; Myeloid Differentiation Factor 88; Neoplastic Stem Cells; Paclitaxel; Triterpenes; Ursolic Acid; Xenograft Model Antitumor Assays | 2020 |
Ursolic acid derivative UA232 evokes apoptosis of lung cancer cells induced by endoplasmic reticulum stress.
Topics: A549 Cells; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Endoplasmic Reticulum Stress; Humans; Inhibitory Concentration 50; Lung Neoplasms; Signal Transduction; Time Factors; Triterpenes; Ursolic Acid | 2020 |
Autophagy inhibition enhances the inhibitory effects of ursolic acid on lung cancer cells.
Topics: A549 Cells; Animals; Apoptosis; Autophagy; Autophagy-Related Protein 5; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Chloroquine; Humans; Lung Neoplasms; MCF-7 Cells; Mice; Mice, Inbred C57BL; Signal Transduction; Triterpenes; Ursolic Acid | 2020 |
Simultaneous inhibition of growth and metastasis of hepatocellular carcinoma by co-delivery of ursolic acid and sorafenib using lactobionic acid modified and pH-sensitive chitosan-conjugated mesoporous silica nanocomplex.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Chitosan; Delayed-Action Preparations; Disaccharides; Drug Synergism; Humans; Hydrogen-Ion Concentration; Liver Neoplasms; Lung Neoplasms; Male; Mice; Nanoparticles; Niacinamide; Phenylurea Compounds; Porosity; Rats; Silicon Dioxide; Sorafenib; Triterpenes; Ursolic Acid | 2017 |
Ursolic Acid Attenuates TGF-β1-Induced Epithelial-Mesenchymal Transition in NSCLC by Targeting Integrin αVβ5/MMPs Signaling.
Topics: Antineoplastic Agents, Phytogenic; Cadherins; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Proliferation; Epithelial-Mesenchymal Transition; Humans; Lung Neoplasms; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Receptors, Vitronectin; Signal Transduction; Transforming Growth Factor beta1; Triterpenes; Ursolic Acid | 2019 |
Anti-Proliferative Activity of Triterpenoids and Sterols Isolated from Alstonia scholaris against Non-Small-Cell Lung Carcinoma Cells.
Topics: A549 Cells; Alstonia; Antineoplastic Agents; Betulinic Acid; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Humans; Lung Neoplasms; Pentacyclic Triterpenes; Phytosterols; Plant Extracts; Plant Leaves; Sterols; Tetrazolium Salts; Thiazoles; Triterpenes; Ursolic Acid | 2017 |
Ursolic acid promotes apoptosis and mediates transcriptional suppression of CT45A2 gene expression in non-small-cell lung carcinoma harbouring EGFR T790M mutations.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Resistance, Neoplasm; ErbB Receptors; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mice; Mice, Nude; Mutation; Transcriptome; Triterpenes; Ursolic Acid; Xenograft Model Antitumor Assays | 2019 |
Ursolic acid inhibits epithelial-mesenchymal transition by suppressing the expression of astrocyte-elevated gene-1 in human nonsmall cell lung cancer A549 cells.
Topics: Antineoplastic Agents, Phytogenic; Cadherins; Carcinoma, Non-Small-Cell Lung; Cell Adhesion; Cell Adhesion Molecules; Cell Line, Tumor; Dose-Response Relationship, Drug; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Membrane Proteins; NF-kappa B; RNA-Binding Proteins; Signal Transduction; Triterpenes; Ursolic Acid; Vimentin | 2013 |
Activation of SAPK/JNK mediated the inhibition and reciprocal interaction of DNA methyltransferase 1 and EZH2 by ursolic acid in human lung cancer cells.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Drug Screening Assays, Antitumor; Enhancer of Zeste Homolog 2 Protein; Humans; Lung Neoplasms; Mitogen-Activated Protein Kinases; Phosphorylation; Polycomb Repressive Complex 2; Protein Processing, Post-Translational; Signal Transduction; Triterpenes; Ursolic Acid | 2015 |
Ursolic acid exerts anti-cancer activity by suppressing vaccinia-related kinase 1-mediated damage repair in lung cancer cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Binding Sites; Catalytic Domain; Cell Line, Tumor; Disease Models, Animal; DNA Damage; Doxorubicin; Drug Synergism; Enzyme Activation; Humans; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; Models, Molecular; Molecular Conformation; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Interaction Domains and Motifs; Protein Serine-Threonine Kinases; Triterpenes; Ursolic Acid; Xenograft Model Antitumor Assays | 2015 |
Hypoxia pathway and hypoxia-mediated extensive extramedullary hematopoiesis are involved in ursolic acid's anti-metastatic effect in 4T1 tumor bearing mice.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Female; Hematopoiesis, Extramedullary; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lung Neoplasms; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Neovascularization, Pathologic; Signal Transduction; Triterpenes; Ursolic Acid; Von Hippel-Lindau Tumor Suppressor Protein | 2016 |
Blockage of epithelial to mesenchymal transition and upregulation of let 7b are critically involved in ursolic acid induced apoptosis in malignant mesothelioma cell.
Topics: Apoptosis; Blotting, Western; Cell Cycle; Cell Line, Tumor; Epithelial-Mesenchymal Transition; Humans; Lung Neoplasms; Mesothelioma; Mesothelioma, Malignant; MicroRNAs; Real-Time Polymerase Chain Reaction; Transfection; Triterpenes; Ursolic Acid | 2016 |
Enhancement of chemotherapeutic agent-induced apoptosis by inhibition of NF-kappaB using ursolic acid.
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; BH3 Interacting Domain Death Agonist Protein; Blotting, Western; Caspase 8; Cell Proliferation; Cells, Cultured; Cisplatin; Cytochromes c; Drug Synergism; Fas Ligand Protein; fas Receptor; Female; Flow Cytometry; Humans; Liver; Luciferases; Lung; Lung Neoplasms; Mice; NF-kappa B; Protein Transport; RNA, Small Interfering; Signal Transduction; Triterpenes; Ursolic Acid; Uterine Cervical Neoplasms | 2010 |
Inhibition of cell proliferation, invasion and migration by ursolic acid in human lung cancer cell lines.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Lung; Lung Neoplasms; Neoplasm Proteins; Triterpenes; Ursolic Acid | 2011 |
Suppression of AMF/PGI-mediated tumorigenic activities by ursolic acid in cultured hepatoma cells and in a mouse model.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Cell Adhesion; Cell Movement; Cell Proliferation; Cisplatin; Disease Models, Animal; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Flavones; Fluorescent Antibody Technique; Glucose-6-Phosphate Isomerase; Humans; Immunoprecipitation; Liver Neoplasms; Luciferases; Lung Neoplasms; Male; Matrix Metalloproteinase 3; Mice; Mice, Nude; Neovascularization, Pathologic; Oleanolic Acid; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; rhoA GTP-Binding Protein; Signal Transduction; Transforming Growth Factor beta; Triterpenes; Tumor Cells, Cultured; Ursolic Acid | 2013 |
Ursolic acid inhibits cigarette smoke extract-induced human bronchial epithelial cell injury and prevents development of lung cancer.
Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Alkylating; Bronchioles; Cell Proliferation; Cell Shape; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Chemoprevention; Cyclophosphamide; Cytoprotection; DNA Damage; Epithelial Cells; Glutathione; Glutathione Transferase; Humans; L-Lactate Dehydrogenase; Lung Neoplasms; Metabolic Detoxication, Phase II; Mice; Mice, Nude; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Nicotiana; Smoke; Triterpenes; Tumor Burden; Ursolic Acid; Xenograft Model Antitumor Assays | 2012 |
Proliferative inhibition, cell-cycle dysregulation, and induction of apoptosis by ursolic acid in human non-small cell lung cancer A549 cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Cycle Proteins; Cell Division; Cell Line, Tumor; Enzyme-Linked Immunosorbent Assay; Fas Ligand Protein; Humans; Lung Neoplasms; Membrane Glycoproteins; NF-kappa B; Signal Transduction; Triterpenes; Ursolic Acid | 2004 |