ursolic acid has been researched along with Inflammation in 44 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (2.27) | 18.2507 |
| 2000's | 3 (6.82) | 29.6817 |
| 2010's | 29 (65.91) | 24.3611 |
| 2020's | 11 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Edwards, BS; Graves, SW; Saunders, MJ; Sklar, LA; Zhu, J | 1 |
| Fang, W; Li, SJ; Lin, ZH; Liu, JP; Liu, Q; Mei, JH; Shi, LQ; Sun, WG; Wang, ZY; Xie, BY; Yang, XL; Zou, Y | 1 |
| Feng, Z; Lan, Y; Li, C; Mei, X; Nong, Z; Wei, X; Zhai, Y; Zou, M | 1 |
| Al-Gareeb, AI; Al-Kuraishy, HM; Alexiou, A; Batiha, GE; Negm, WA | 1 |
| Choi, JH; Choi, S; Choi, YJ; Chung, HY; Hyun, MK; Kim, DH; Lee, JY; Noh, SG; Park, CH; Park, D | 1 |
| Bakhtiari, N; Hojati, V; Honarvar, F; Javan, M; Zare, L | 1 |
| Cui, C; Shi, J; Xing, Z; Zhang, H; Zheng, J | 1 |
| Cai, Q; Gao, L; Hua, Q; Lei, P; Li, Z; Song, P; Zhou, L | 1 |
| Akhtar, S; Almubrad, T; Khan, AA; Masmali, A; Nagarajan, RP; Samivel, R; Subramanian, U | 1 |
| Agrawal, A; Kumar, R; Rathor, R; Singh, SN; Suryakumar, G | 1 |
| Chang, SH; Chen, YL; Hsieh, PS; Hsieh, PW; Hwang, TL; Korinek, M; Wu, YH | 1 |
| Choi, YA; Dhakal, H; Khang, D; Kim, MJ; Kim, N; Kim, SH; Kwon, TK; Lee, S | 1 |
| Acuña Ortega, N; González-Ortiz, M; Martínez-Abundis, E; Ramírez-Rodríguez, AM | 1 |
| Bai, G; Hou, Y; Ma, X; Nie, Q; Shen, Y; Wang, Z; Zhang, M; Zhang, Y | 1 |
| Androulakis, IP; Cheng, D; Guo, Y; Kong, AN; Li, W; Wang, C; Wu, R; Yang, Y; Zhang, C | 1 |
| Kaster, MP; Pazini, FL; Ramos-Hryb, AB; Rodrigues, ALS | 1 |
| Cheng, Y; Gong, Y; Qi, MY; Wang, XT; Yang, JJ; Zhao, JG; Zhou, B | 1 |
| Chen, R; Wang, Z; Zhang, H; Zhang, Z | 1 |
| Hao, Z; Li, Q; Zeng, X; Zhao, W | 1 |
| Cheng, Y; Qi, MY; Wang, XT; Xu, HL; Yang, JJ; Zhao, JG; Zhou, YJ | 1 |
| Li, J; Li, N; Liu, M; Lu, Y; Shao, Y; Sun, B; Yan, S | 1 |
| Li, C; Li, T; Peng, M; Qiang, L; Wang, J; Xu, Y | 1 |
| Cheng, YD; Lan, WC; Lee, SC; Lin, LW; Tsai, FH; Wu, CR | 1 |
| Birla, H; Dilnashin, H; Keswani, C; Rai, SN; Rathore, AS; Singh, R; Singh, RK; Singh, SP; Singh, SS; Zahra, W | 1 |
| Jing, F; Liu, G; Quan, X; Sui, Z; Zhao, J; Zhao, W; Zheng, H | 1 |
| Aguiar, JA; de Castro Campos Pinto, N; de Oliveira, LG; Fabri, RL; Florêncio, JR; Garcia, RA; Ribeiro, A; Scio, E | 1 |
| Li, C; Li, Y; Liu, Y; Xie, L; Xue, C; Yang, T; Zhou, P | 1 |
| Ding, J; Liu, CM; Ma, JQ; Xiao, ZH | 1 |
| Carbajal, S; Cho, J; DiGiovanni, J; Junco, J; Rho, O; Siegel, D; Slaga, TJ | 1 |
| Aggarwal, BB; Gupta, SC; Prasad, S; Sung, B; Tyagi, AK; Yadav, VR | 1 |
| Fan, D; Iwanowycz, S; Leng, S; Razani, B; Saaoud, F; Sergin, I; Wang, J; Wang, Y | 1 |
| Bhat, RA; Kalra, J; Kumar, D; Lingaraju, MC; Pathak, NN; Tandan, SK | 1 |
| Kashyap, D; Punia, S; Sharma, A; Sharma, AK; Tuli, HS | 1 |
| Chen, Y; Lan, T; Peng, J; Ren, X; Shao, Z; Yang, C | 1 |
| Han, HJ; Jeon, MJ; Kang, SY; Kim, HW; Kwon, YB; Lee, HJ; Lee, JH; Roh, DH; Seo, HS; Uh, DK; Yoon, SY | 1 |
| Hu, B; Liu, CM; Lu, J; Shan, Q; Wang, YJ; Wu, DM; Ye, Q; Zhang, ZF; Zheng, YL | 1 |
| Lu, J; Ruan, J; Shan, Q; Sun, X; Wang, XH; Wang, YJ; Wu, DM; Zhang, ZF; Zheng, YL; Zheng, ZH | 1 |
| Cheng, W; Hu, B; Lu, J; Shan, Q; Wu, DM; Zhang, ZF; Zheng, YL | 1 |
| Baggio, CH; da Silva, CF; das Neves, TL; Horst, H; Kanazawa, LK; Pizzolatti, MG; Rodrigues, MR; Santos, AR; Werner, MF | 1 |
| Chang, YS; Ho, YL; Lai, SC; Liao, CR; Peng, WH | 1 |
| Hong, JH; Kim, SH; Lee, YC | 1 |
| Aquino, RP; Brkic, D; Fkih-Tetouani, S; Ilidrissi, A; Ismaili, H; Sosa, S; Touati, D; Tubaro, A | 1 |
| Ikeda, Y; Murakami, A; Ohigashi, H | 1 |
| Liu, J | 1 |
5 review(s) available for ursolic acid and Inflammation
| Article | Year |
|---|---|
Ursolic acid and SARS-CoV-2 infection: a new horizon and perspective.
Topics: Acute Lung Injury; Anti-Inflammatory Agents; Antioxidants; Antiviral Agents; COVID-19 Drug Treatment; Cytokines; Humans; Inflammation; Oleanolic Acid; Reactive Oxygen Species; Respiratory Distress Syndrome; SARS-CoV-2; Ursolic Acid | 2022 |
Therapeutic Potential of Ursolic Acid to Manage Neurodegenerative and Psychiatric Diseases.
Topics: Animals; Disease Models, Animal; Humans; Inflammation; Mental Disorders; Neurodegenerative Diseases; Oxidative Stress; Triterpenes; Ursolic Acid | 2017 |
Ursolic Acid and Oleanolic Acid: Pentacyclic Terpenoids with Promising Anti-Inflammatory Activities.
Topics: Animals; Anti-Inflammatory Agents; Drug Discovery; Humans; Inflammation; Inflammation Mediators; Molecular Targeted Therapy; Oleanolic Acid; Patents as Topic; Signal Transduction; Triterpenes; Ursolic Acid | 2016 |
Ursolic acid: an anti- and pro-inflammatory triterpenoid.
Topics: Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Antimutagenic Agents; Apoptosis; Humans; Inflammation; Liver Diseases; Oxidative Stress; Plants, Medicinal; Triterpenes; Ursolic Acid | 2008 |
Pharmacology of oleanolic acid and ursolic acid.
Topics: Antineoplastic Agents, Phytogenic; Humans; Hyperlipidemias; Inflammation; Liver; Oleanolic Acid; Triterpenes; Ursolic Acid | 1995 |
1 trial(s) available for ursolic acid and Inflammation
| Article | Year |
|---|---|
Effect of Ursolic Acid on Metabolic Syndrome, Insulin Sensitivity, and Inflammation.
Topics: Adult; Blood Glucose; C-Reactive Protein; Double-Blind Method; Female; Humans; Inflammation; Insulin; Insulin Resistance; Interleukin-6; Male; Metabolic Syndrome; Middle Aged; Triterpenes; Ursolic Acid; Waist Circumference | 2017 |
38 other study(ies) available for ursolic acid and Inflammation
| Article | Year |
|---|---|
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Proteins; High-Throughput Screening Assays; Humans; Inflammation; Kinetics; Microspheres; Peptide Hydrolases; Peptides; Reproducibility of Results; Temperature | 2010 |
Betulin isolated from Pyrola incarnata Fisch. inhibited lipopolysaccharide (LPS)-induced neuroinflammation with the guidance of computer-aided drug design.
Topics: Animals; Cell Line; Dose-Response Relationship, Drug; Drug Design; Inflammation; Inflammation Mediators; Lipopolysaccharides; Mice; Molecular Conformation; Nitric Oxide; Nitric Oxide Synthase Type II; Pyrola; Stereoisomerism; Structure-Activity Relationship; Triterpenes | 2020 |
Ursolic acid represses influenza A virus-triggered inflammation and oxidative stress in A549 cells by modulating the miR-34c-5p/TLR5 axis.
Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Humans; Inflammation; Influenza A virus; MicroRNAs; Oxidative Stress; Toll-Like Receptor 5; Triterpenes; Ursolic Acid | 2022 |
Protective mechanisms of loquat leaf extract and ursolic acid against diabetic pro-inflammation.
Topics: AMP-Activated Protein Kinases; Animals; Antioxidants; Diabetes Mellitus, Experimental; Eriobotrya; Hyperglycemia; Inflammation; Mice; Oleanolic Acid; Plant Extracts; Ursolic Acid | 2022 |
Ursolic Acid Enhances Myelin Repair in Adult Mice Brains and Stimulates Exhausted Oligodendrocyte Progenitors to Remyelinate.
Topics: Animals; Anti-Inflammatory Agents; Corpus Callosum; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Glial Fibrillary Acidic Protein; Gliosis; Inflammation; Interleukin-10; Mice; Mice, Inbred C57BL; Myelin Sheath; Oligodendrocyte Precursor Cells; Oligodendroglia; Tumor Necrosis Factor-alpha; Ursolic Acid | 2022 |
Ursolic acid ameliorates traumatic brain injury in mice by regulating microRNA-141-mediated PDCD4/PI3K/AKT signaling pathway.
Topics: Animals; Apoptosis; Brain Injuries, Traumatic; Inflammation; Mice; MicroRNAs; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Ursolic Acid | 2023 |
Ursolic Acid Alleviates Neuroinflammation after Intracerebral Hemorrhage by Mediating Microglial Pyroptosis via the NF-κB/NLRP3/GSDMD Pathway.
Topics: Animals; Cerebral Hemorrhage; Inflammation; Microglia; Molecular Docking Simulation; Neuroinflammatory Diseases; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Pyroptosis; Rats; Rats, Sprague-Dawley; Signal Transduction; Ursolic Acid | 2023 |
Inhibitory Effect of Ursolic Acid on Ultraviolet B Radiation-Induced Oxidative Stress and Proinflammatory Response-Mediated Senescence in Human Skin Dermal Fibroblasts.
Topics: bcl-2-Associated X Protein; Caspase 3; Cell Nucleus; Cell Survival; Cellular Senescence; Dermis; DNA Damage; Fibroblasts; Humans; Inflammation; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Membrane Potential, Mitochondrial; NF-kappa B; Oxidative Stress; Reactive Oxygen Species; RNA, Messenger; Thiobarbituric Acid Reactive Substances; Triterpenes; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53; Ultraviolet Rays; Ursolic Acid | 2020 |
Ursolic acid ameliorates hypobaric hypoxia-induced skeletal muscle protein loss via upregulating Akt pathway: An experimental study using rat model.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cyclooxygenase Inhibitors; Disease Models, Animal; Gene Expression Regulation; Hypoxia; Inflammation; Male; Muscle Proteins; Muscle, Skeletal; Oxidation-Reduction; Oxidative Stress; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Triterpenes; Up-Regulation; Ursolic Acid | 2021 |
Randialic acid B and tomentosolic acid block formyl peptide receptor 1 in human neutrophils and attenuate psoriasis-like inflammation in vivo.
Topics: Adult; Animals; Cell Line; Cells, Cultured; Female; HEK293 Cells; Humans; Imiquimod; Inflammation; Male; Mice; Mice, Inbred BALB C; Neutrophils; Psoriasis; Receptors, Formyl Peptide; Triterpenes; Ursolic Acid; Young Adult | 2021 |
Ursolic acid inhibits FcεRI-mediated mast cell activation and allergic inflammation.
Topics: Anaphylaxis; Animals; Anti-Inflammatory Agents; Calcium; Cell Degranulation; Cytokines; Inflammation; Male; Mast Cell Activation Disorders; Mast Cells; Mice; Mice, Inbred ICR; Rats; Rats, Sprague-Dawley; Signal Transduction; Triterpenes; Ursolic Acid | 2021 |
Ursolic Acid, a Natural Nutraceutical Agent, Targets Caspase3 and Alleviates Inflammation-Associated Downstream Signal Transduction.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Caspase 3; Caspase Inhibitors; Cell Line; Dietary Supplements; Epithelial Cells; Humans; Inflammation; Molecular Docking Simulation; Molecular Imaging; NF-kappa B; Signal Transduction; STAT3 Transcription Factor; Triterpenes; Ursolic Acid | 2017 |
Pharmacokinetics and Pharmacodynamics of the Triterpenoid Ursolic Acid in Regulating the Antioxidant, Anti-inflammatory, and Epigenetic Gene Responses in Rat Leukocytes.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; DNA Modification Methylases; Epigenesis, Genetic; Histone Deacetylases; Inflammation; Rats; Rats, Sprague-Dawley; Triterpenes; Ursolic Acid | 2017 |
Ursolic acid ameliorates oxidative stress, inflammation and fibrosis in diabetic cardiomyopathy rats.
Topics: Animals; Chemokine CCL2; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Down-Regulation; Fibrosis; Gene Expression Regulation; Inflammation; Male; Matrix Metalloproteinase 2; Oxidative Stress; Rats; Rats, Sprague-Dawley; Streptozocin; Transforming Growth Factor beta1; Triterpenes; Tumor Necrosis Factor-alpha; Up-Regulation; Ursolic Acid | 2018 |
Oral supplementation with ursolic acid ameliorates sepsis-induced acute kidney injury in a mouse model by inhibiting oxidative stress and inflammatory responses.
Topics: Acute Kidney Injury; Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Antioxidants; Disease Models, Animal; Inflammation; Male; Mice; Oxidative Stress; Sepsis; Triterpenes; Ursolic Acid | 2018 |
Ursolic Acid Attenuates Atherosclerosis in ApoE
Topics: Animals; Anti-Inflammatory Agents; Aorta; Apolipoproteins E; Atherosclerosis; Disease Models, Animal; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myeloid Differentiation Factor 88; NF-kappa B; Reactive Oxygen Species; RNA, Small Interfering; Scavenger Receptors, Class E; Signal Transduction; Toll-Like Receptor 4; Triterpenes; Ursolic Acid | 2018 |
Ursolic acid improves diabetic nephropathy via suppression of oxidative stress and inflammation in streptozotocin-induced rats.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Inflammation; Inflammation Mediators; Kidney; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Streptozocin; Triterpenes; Ursolic Acid | 2018 |
Ursolic acid alleviates inflammation and against diabetes‑induced nephropathy through TLR4‑mediated inflammatory pathway.
Topics: Animals; Diabetic Nephropathies; Disease Models, Animal; Drugs, Chinese Herbal; Gene Expression Regulation; Humans; Inflammation; Kidney; Mice; Myeloid Differentiation Factor 88; NF-kappa B; Oxidative Stress; Rats; Signal Transduction; Toll-Like Receptor 4; Triterpenes; Tumor Necrosis Factor-alpha; Ursolic Acid | 2018 |
Modification of Cysteine 179 in IKKβ by Ursolic Acid Inhibits Titanium-Wear-Particle-Induced Inflammation, Osteoclastogenesis, and Hydroxylapatite Resorption.
Topics: Animals; Bone Resorption; Cysteine; Durapatite; I-kappa B Kinase; Inflammation; Joint Prosthesis; Mice; Mice, Inbred C57BL; Monocytes; Osteoclasts; Primary Cell Culture; Prosthesis Failure; RAW 264.7 Cells; Titanium; Triterpenes; Ursolic Acid | 2018 |
Steroid-Enriched Fraction of Achyranthes bidentata Protects Amyloid β Peptide 1-40-Induced Cognitive Dysfunction and Neuroinflammation in Rats.
Topics: Acetylcholinesterase; Achyranthes; Amyloid beta-Peptides; Animals; Antioxidants; Astrocytes; Behavior, Animal; Brain; Cognitive Dysfunction; Cytokines; Ecdysterone; Glutathione; Hippocampus; Inflammation; Male; Malondialdehyde; MAP Kinase Signaling System; Maze Learning; Memory; Microglia; Neuroprotective Agents; NF-kappa B; Oleanolic Acid; Peptide Fragments; Rats, Sprague-Dawley; Steroids; Triterpenes; Ursolic Acid | 2019 |
Anti-inflammatory Activity of Ursolic Acid in MPTP-Induced Parkinsonian Mouse Model.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Anti-Inflammatory Agents; Antiparkinson Agents; Brain; Catalase; Fluorescent Antibody Technique; Glutathione; Inflammation; Lipid Peroxidation; Male; Malondialdehyde; Mice; Nitrites; Parkinsonian Disorders; Psychomotor Performance; Real-Time Polymerase Chain Reaction; Rotarod Performance Test; Triterpenes; Ursolic Acid | 2019 |
Ursolic acid exhibits anti-inflammatory effects through blocking TLR4-MyD88 pathway mediated by autophagy.
Topics: Animals; Anti-Inflammatory Agents; Autophagic Cell Death; Cytokines; Inflammation; Lipopolysaccharides; Macrophages; Mice; Myeloid Differentiation Factor 88; RAW 264.7 Cells; Signal Transduction; Toll-Like Receptor 4; Triterpenes; Ursolic Acid | 2019 |
Anti-inflammatory and antioxidative effects of the methanolic extract of the aerial parts of Mitracarpus frigidus in established animal models.
Topics: Animals; Antioxidants; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Edema; Female; Inflammation; Inflammation Mediators; Kaempferols; Male; Mice; Naphthoquinones; Oxidative Stress; Phytotherapy; Plant Components, Aerial; Plant Extracts; Rats, Wistar; Rubiaceae; Rutin; Triterpenes; Ursolic Acid | 2014 |
Powerful protection against renal ischemia reperfusion injury by T cell-specific NF-κB inhibition.
Topics: Animals; Blood Urea Nitrogen; CD4-Positive T-Lymphocytes; Creatinine; Cytokines; Immunohistochemistry; Inflammation; Kidney; Male; Mice; Mice, Inbred C57BL; Neutrophil Infiltration; Neutrophils; NF-kappa B; Real-Time Polymerase Chain Reaction; Reperfusion Injury; Time Factors; Triterpenes; Ursolic Acid | 2014 |
Ursolic acid ameliorates carbon tetrachloride-induced oxidative DNA damage and inflammation in mouse kidney by inhibiting the STAT3 and NF-κB activities.
Topics: Animals; Antioxidants; Carbon Tetrachloride; Cyclooxygenase 2; DNA Damage; Inflammation; Interleukin-17; Interleukin-6; Kidney; Lipid Peroxidation; Male; Mice; Mice, Inbred ICR; NF-kappa B; Oxidative Stress; Phosphorylation; Reactive Oxygen Species; Renal Insufficiency; Signal Transduction; STAT3 Transcription Factor; Triterpenes; Tumor Necrosis Factor-alpha; Ursolic Acid | 2014 |
Effect of Combined Treatment with Ursolic Acid and Resveratrol on Skin Tumor Promotion by 12-O-Tetradecanoylphorbol-13-Acetate.
Topics: Animals; Anticarcinogenic Agents; Carcinogenesis; Cell Nucleus; Cell Proliferation; Cytosol; Female; Inflammation; Male; Mice; Mice, Inbred ICR; Protein Binding; Resveratrol; Signal Transduction; Skin; Skin Neoplasms; Stilbenes; Tetradecanoylphorbol Acetate; Triterpenes; Ursolic Acid | 2015 |
Ursolic acid inhibits the growth of human pancreatic cancer and enhances the antitumor potential of gemcitabine in an orthotopic mouse model through suppression of the inflammatory microenvironment.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Drug Resistance, Neoplasm; Drug Synergism; Gemcitabine; Humans; Inflammation; Mice; Mice, Nude; Pancreatic Neoplasms; Triterpenes; Tumor Microenvironment; Ursolic Acid; Xenograft Model Antitumor Assays | 2016 |
Ursolic acid enhances macrophage autophagy and attenuates atherogenesis.
Topics: Animals; Atherosclerosis; ATP Binding Cassette Transporter 1; ATP Binding Cassette Transporter, Subfamily G, Member 1; Autophagy; Autophagy-Related Protein 5; Autophagy-Related Proteins; Carrier Proteins; Cholesterol; Diet, Western; Gene Expression Regulation; Inflammation; Interleukin-1beta; Lipopolysaccharides; Macrophages; Mice; Mice, Knockout; RAW 264.7 Cells; Receptors, LDL; Triterpenes; Ursolic Acid | 2016 |
Effect of ursolic acid in attenuating chronic constriction injury-induced neuropathic pain in rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Constriction; Cytokines; Disease Models, Animal; Hyperalgesia; Inflammation; Male; Malondialdehyde; Neuralgia; Nitric Oxide; Oxidative Stress; Peroxidase; Protein Carbonylation; Rats; Sciatic Nerve; Spinal Cord; Superoxides; Triterpenes; Ursolic Acid | 2016 |
Renoprotective effects of ursolic acid on ischemia/reperfusion‑induced acute kidney injury through oxidative stress, inflammation and the inhibition of STAT3 and NF‑κB activities.
Topics: Acute Kidney Injury; Animals; Anti-Inflammatory Agents; Antioxidants; Inflammation; Kidney; Male; NF-kappa B; Oxidative Stress; Prunella; Rats; Rats, Sprague-Dawley; Reperfusion Injury; STAT3 Transcription Factor; Triterpenes; Ursolic Acid | 2016 |
The anti-arthritic effect of ursolic acid on zymosan-induced acute inflammation and adjuvant-induced chronic arthritis models.
Topics: Acute Disease; Animals; Antirheumatic Agents; Arthritis, Experimental; Cell Movement; Chronic Disease; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Inflammation; Leukocytes; Mice; Mice, Inbred ICR; Oldenlandia; Pain; Plant Extracts; Rats; Rats, Sprague-Dawley; Triterpenes; Ursolic Acid; Zymosan | 2008 |
Ursolic acid attenuates D-galactose-induced inflammatory response in mouse prefrontal cortex through inhibiting AGEs/RAGE/NF-κB pathway activation.
Topics: Animals; Disease Models, Animal; Galactose; Glycation End Products, Advanced; Inflammation; Male; Mice; Mitogen-Activated Protein Kinases; NF-kappa B; Prefrontal Cortex; Signal Transduction; Triterpenes; Ursolic Acid | 2010 |
Ursolic acid attenuates lipopolysaccharide-induced cognitive deficits in mouse brain through suppressing p38/NF-κB mediated inflammatory pathways.
Topics: Animals; Brain; Cognition; Inflammation; Lipopolysaccharides; Maze Learning; Mice; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Signal Transduction; Triterpenes; Ursolic Acid | 2011 |
Ursolic acid improves high fat diet-induced cognitive impairments by blocking endoplasmic reticulum stress and IκB kinase β/nuclear factor-κB-mediated inflammatory pathways in mice.
Topics: Animals; Behavior, Animal; Blotting, Western; Cognition Disorders; Cyclooxygenase Inhibitors; Diet, High-Fat; Dietary Fats; Endoplasmic Reticulum Stress; Fluorescent Antibody Technique; Hippocampus; I-kappa B Kinase; Immunohistochemistry; Inflammation; Insulin; Male; Maze Learning; Mice; Mice, Inbred C57BL; NF-kappa B; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Signal Transduction; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; TOR Serine-Threonine Kinases; Triterpenes; Ursolic Acid | 2011 |
Antinociceptive and anti-inflammatory potential of extract and isolated compounds from the leaves of Salvia officinalis in mice.
Topics: Abietanes; Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Inflammation; Lethal Dose 50; Mice; Motor Activity; Narcotic Antagonists; Oleanolic Acid; Pain; Pain Measurement; Plant Extracts; Plant Leaves; Plants, Medicinal; Salvia officinalis; Time Factors; Triterpenes; Ursolic Acid | 2012 |
Analgesic and anti-inflammatory activities of the methanol extract of Elaeagnus oldhamii Maxim. in mice.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Antioxidants; Behavior, Animal; Carrageenan; Cyclooxygenase 2 Inhibitors; Edema; Elaeagnaceae; Flavonoids; Flavonols; Formaldehyde; Inflammation; Inflammation Mediators; Liver; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Nitric Oxide; Oleanolic Acid; Pain; Phytotherapy; Plant Extracts; Polyphenols; Triterpenes; Ursolic Acid | 2012 |
Ursolic acid, a potential PPARγ agonist, suppresses ovalbumin-induced airway inflammation and Penh by down-regulating IL-5, IL-13, and IL-17 in a mouse model of allergic asthma.
Topics: Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Cell Count; Cell Line; Cyclosporine; Disease Models, Animal; Down-Regulation; Eosinophils; Female; GATA3 Transcription Factor; Hypersensitivity; Immunoglobulin E; Inflammation; Interleukin-13; Interleukin-17; Interleukin-5; Interleukins; Lung; Macrophages; Mice; Mice, Inbred BALB C; Ovalbumin; PPAR gamma; RNA, Messenger; STAT6 Transcription Factor; Th2 Cells; Triterpenes; Ursolic Acid | 2013 |
Topical anti-inflammatory activity of extracts and compounds from Thymus broussonettii.
Topics: Administration, Topical; Animals; Biological Assay; Croton Oil; Dermatologic Agents; Flavonoids; Glycosides; Inflammation; Lamiaceae; Male; Mice; Oleanolic Acid; Plant Extracts; Triterpenes; Ursolic Acid | 2002 |