ursolic acid has been researched along with Disease Models, Animal in 76 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (1.32) | 18.2507 |
| 2000's | 6 (7.89) | 29.6817 |
| 2010's | 51 (67.11) | 24.3611 |
| 2020's | 18 (23.68) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Y; Huang, C; Liu, F; Zhao, L; Zheng, Y | 1 |
| Dong, H; Guo, Z; Li, T; Liu, Y; Tang, Z; Wang, N; Wang, W; Wei, X; Wu, H; Xiao, X | 1 |
| Jiang, SN; Liu, X; Piao, L; Xu, H | 1 |
| Bakhtiari, N; Hojati, V; Honarvar, F; Javan, M; Zare, L | 1 |
| Chen, H; Chen, J; Li, C; Tan, H; Yuan, W; Zhang, W | 1 |
| Chen, H; Gao, X; He, K; Li, C; Li, H; Li, X; Liu, C; Wei, Q; Zhang, Z | 1 |
| Chivandi, E; Dangarembizi, R; Erlwanger, KH; Mukonowenzou, NC; Nkomozepi, P | 1 |
| Deng, C; Dong, W; Guo, Z; Han, Z; Sun, N; Wang, H; Zhang, R; Zhuang, G | 1 |
| Huang, C; Liu, C; Luo, F; Luo, Q; Wan, S; Zhu, X | 1 |
| Jin, C; Jin, CM; Jin, LL; Liu, F; Wei, ZY; Zhang, LH | 1 |
| Birla, H; Dilnashin, H; Keswani, C; Rai, SN; Rathore, AS; Singh, R; Singh, RK; Singh, SP; Singh, SS; Zahra, W | 1 |
| Deng, C; Dong, W; Duan, Y; Guo, Z; Han, Z; Sun, N; Wang, H; Zhang, R; Zhao, Q; Zhuang, G | 1 |
| Iwasa, K; Maruyama, K; Sakemoto, C; Shimizu, K; Yamamoto, S; Yoshikawa, K | 1 |
| Agrawal, A; Kumar, R; Rathor, R; Singh, SN; Suryakumar, G | 1 |
| Abdelfatah, S; Efferth, T; Naß, J | 1 |
| Ahmed, T; Amber, S; Hassan, D; Mirza, FJ; Zahid, S | 1 |
| Fang, X; Huang, C; Liu, Y; Long, J; Meng, X; Xie, X; Xu, D | 1 |
| Chai, K; Chen, G; Li, F; Li, J; Li, M; Li, Q; Lu, Y; Sheng, Q; Wang, Y | 1 |
| Gomes, TL; Katashima, CK; Pichard, C; Pimentel, GD; Silva, VR | 1 |
| Khoo, BC; Loke, WK; Tang, FR; Wong, P | 1 |
| González-Chávez, MM; Pérez-González, C; Pérez-Gutiérrez, S; Ramos-Velázquez, CS; Sánchez-Mendoza, E; Serrano-Vega, R | 1 |
| Choi, H; Choi, JK; Ha, YS; Jeong, NH; Kim, SH; Kwon, TK; Lee, B; Lee, JY; Lee, S; Lee, SR; Lee, SW; Park, PH; Rho, MC; Shin, TY; Yoo, J | 1 |
| Kaster, MP; Pazini, FL; Ramos-Hryb, AB; Rodrigues, ALS | 1 |
| Cunha, MP; Kaster, MP; Lieberknecht, V; Pazini, FL; Prediger, RDS; Ramos-Hryb, AB; Rodrigues, ALS | 1 |
| Cao, J; Liu, C; Shen, Y; Yin, J; Zhang, H | 1 |
| Duan, J; Guo, J; Jou, D; Li, C; Li, S; Lin, J; Lin, L; Liu, T; Lv, J; Ma, H; Shi, W; Tao, J; Wang, Y; Yan, D; Zhai, M; Zhang, C | 1 |
| Chen, R; Wang, Z; Zhang, H; Zhang, Z | 1 |
| Hao, Z; Li, Q; Zeng, X; Zhao, W | 1 |
| Ahuja, S; Akhtar, A; Kumar, A; Mourya, A; Sah, SP | 1 |
| Abu-Gharbieh, E; Almasri, IM; Bustanji, Y; Shehab, NG | 1 |
| Bethea, JR; Bigford, GE; Bracchi-Ricard, VC; Darr, AJ; Gao, H; Nash, MS | 1 |
| Li, J; Li, N; Liu, M; Lu, Y; Shao, Y; Sun, B; Yan, S | 1 |
| Bannerjee, S; Bhattacharjee, P; Biswas, S; Harwansh, RK; Mukherjee, PK | 1 |
| Aartsma-Rus, A; Adamzek, K; Boertje-van der Meulen, JW; Putker, K; van de Vijver, D; van Putten, M; Verhaart, IEC | 1 |
| Cheng, D; Hudlikar, R; Kong, AN; Kuo, HC; Li, S; Lu, Y; Ramirez, CN; Sargsyan, D; Wang, C; Wang, L; Wu, R; Yang, Y; Yin, R | 1 |
| Cunha, WR; da Silva Ferreira, D; de Albuquerque, S; do Prado Júnior, JC; e Silva, ML; Esperandim, VR; Kuehn, CC; Toldo, MP | 1 |
| Aguiar, JA; de Castro Campos Pinto, N; de Oliveira, LG; Fabri, RL; Florêncio, JR; Garcia, RA; Ribeiro, A; Scio, E | 1 |
| Chen, K; Feng, L; Guo, F; Huang, C; Li, Y; Liu, X; Wang, R; Wu, Y; Zhu, W | 1 |
| Chun, J; Hwang, SW; Im, JP; Kim, JS; Lee, C | 1 |
| Gao, P; Gu, Z; Hu, Z; Sun, M; Yang, Q; Yuan, Y; Zhang, K | 1 |
| Ding, J; Liu, CM; Ma, JQ; Zhang, L | 1 |
| Guo, B; Li, X; Su, J; Wang, K; Zhang, T; Zhu, T | 1 |
| Dong, X; Huo, L; Liu, L; Liu, S; Qile, M; Yang, B; Yu, J; Yu, S; Zhang, L | 1 |
| Bao, BH; Du, Y; Fu, HJ; Li, JX; Zhao, Y; Zhou, YR | 1 |
| Hanlin, S; Kexuan, T; Ming, Y; Yuliang, W; Zejian, W | 1 |
| Castañeda-Sanchez, JI; Castro-Mussot, ME; Domínguez-López, L; Hernández-Sanchéz, J; Jiménez-Arellanes, A; López-García, S; Luna-Herrera, J | 1 |
| Baek, NI; Choi, KY; Harikishore, A; Jung, HY; Kim, KT; Kim, SH; Kim, YS; Lee, J; Lyu, HN; Oh, E; Ryu, HG; Shin, J; Yoon, HS | 1 |
| Ge, N; Huang, J; Kong, F; Lin, ZM; Meng, Y; Zhang, DL | 1 |
| Campos, BL; Jesus, JA; Kallás, EG; Lago, JH; Laurenti, MD; Levy, D; Passero, LF; Rafael-Fernandes, M; Ribeiro, SP; Santos-Gomes, G; Sessa, DP; Silva, MS; Yamamoto, ES | 1 |
| Balvay, D; Braga, FC; Cassali, GD; Ferreira, Ê; Ferreira, LA; Garofalakis, A; Leite, EA; Lopes, SC; Oliveira, MC; Rocha, TG; Tavitian, B; Veloso, ES | 1 |
| Dhingra, MS; Jena, AK; Karan, M; Kaur, R; Sharma, N; Vasisht, K | 1 |
| Deng, S; He, Z; Wang, Y | 1 |
| Bhat, RA; Kalra, J; Kumar, D; Lingaraju, MC; Pathak, NN; Tandan, SK | 1 |
| Chen, H; Jia, L; Li, T; Liu, Y; Shao, J; Tang, Q; Yang, X; Zheng, G | 1 |
| Cao, J; Chen, JA; Hu, Z; Thomas, SS; Wang, Y; Xu, J; Yu, R | 1 |
| Han, HJ; Jeon, MJ; Kang, SY; Kim, HW; Kwon, YB; Lee, HJ; Lee, JH; Roh, DH; Seo, HS; Uh, DK; Yoon, SY | 1 |
| Hu, B; Liu, CM; Lu, J; Shan, Q; Wang, YJ; Wu, DM; Ye, Q; Zhang, ZF; Zheng, YL | 1 |
| Chang, NC; Chen, TL; Chen, YH; Fong, TH; Huang, CY; Lee, AW; Lin, FY; Shih, CM; Tsao, NW | 1 |
| Bist, P; Hui, KM; Kumar, AP; Lim, LH; Manu, KA; Ong, TH; Ramachandran, L; Sethi, G; Shanmugam, MK; Surana, R | 1 |
| Bernhard, D; Frotschnig, S; Huck, C; Laufer, G; Messner, B; Ploner, C; Ringer, T; Ritsch, A; Steinacher-Nigisch, A; Zeller, I | 1 |
| Chaves, MH; Ferreira, EL; Gomes, BS; Oliveira, FA; Oliveira, JP; Silva, LL; Sousa-Neto, BP | 1 |
| Baggio, CH; da Silva, CF; das Neves, TL; Horst, H; Kanazawa, LK; Pizzolatti, MG; Rodrigues, MR; Santos, AR; Werner, MF | 1 |
| Ha, HK; Jung, DY; Lee, MY; Seo, CS; Shin, HK; Shin, IS | 1 |
| Chang, CD; Liao, MH; Lin, PY; Shih, WL; Wu, HY; Yu, FL | 1 |
| Li, D; Liu, JH; Wang, GL; Wang, L; Wu, LN; Zhu, DZ | 1 |
| Aggarwal, BB; Baladandayuthapani, V; Deorukhkar, A; Diagaradjane, P; Guha, S; Kannappan, R; Krishnan, S; Prasad, S; Reuter, S; Sung, B; Wei, C; Yadav, VR | 1 |
| Afzal, M; Anwar, F; Gupta, G; Kazmi, I | 1 |
| Hong, JH; Kim, SH; Lee, YC | 1 |
| Chen, X; Li, J; Wan, Y; Wei, Y; Zhou, T | 1 |
| Cui, L; Du, Y; Ji, H; Li, L; Liu, H; Wang, L; Zhang, X | 1 |
| Choi, J; Jung, HJ; Lee, KT; Lontsi, D; Park, HJ; Sondengam, BL; Tapondjou, LA | 1 |
| Castilla, V; de Nicolás, R; Egido, J; González-Cabrero, J; Gutierrez, C; Pozo, M | 1 |
| Pugalendi, KV; Saravanan, R; Viswanathan, P | 1 |
| Ahmad, SF; Bani, S; Khan, B; Qazi, GN; Satti, NK; Suri, KA | 1 |
| Cheng, WM; Huang, Y; Li, J; Li, YH; Wang, R; Wang, YY; Wu, Q; Yu, SC | 1 |
| Kirby, GC; Simmonds, MS; Steele, JC; Warhurst, DC | 1 |
2 review(s) available for ursolic acid and Disease Models, Animal
| Article | Year |
|---|---|
Ursolic acid and mechanisms of actions on adipose and muscle tissue: a systematic review.
Topics: Adipose Tissue; Animals; Anti-Obesity Agents; Disease Models, Animal; Energy Metabolism; Humans; Muscle, Skeletal; Obesity; Thermogenesis; Transcription Factors; Triterpenes; Uncoupling Protein 1; Ursolic Acid | 2017 |
Therapeutic Potential of Ursolic Acid to Manage Neurodegenerative and Psychiatric Diseases.
Topics: Animals; Disease Models, Animal; Humans; Inflammation; Mental Disorders; Neurodegenerative Diseases; Oxidative Stress; Triterpenes; Ursolic Acid | 2017 |
74 other study(ies) available for ursolic acid and Disease Models, Animal
| Article | Year |
|---|---|
Regulation of decorin by ursolic acid protects against non-alcoholic steatohepatitis.
Topics: Animals; Cell Hypoxia; Cells, Cultured; Computational Biology; Databases, Genetic; Decorin; Disease Models, Animal; Gene Expression Regulation; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Liver; Male; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Oxidative Stress; Receptor, IGF Type 1; Signal Transduction; Triterpenes; Ursolic Acid | 2021 |
The Synergistic Reducing Drug Resistance Effect of Cisplatin and Ursolic Acid on Osteosarcoma through a Multistep Mechanism Involving Ferritinophagy.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cisplatin; Disease Models, Animal; Ferritins; Humans; Mice; Osteosarcoma; Triterpenes; Ursolic Acid; Xenograft Model Antitumor Assays | 2021 |
Ursolic acid-enriched kudingcha extract enhances the antitumor activity of bacteria-mediated cancer immunotherapy.
Topics: Animals; Bacteria; Disease Models, Animal; Ilex; Immunotherapy; Mice; Neoplasms; Plant Extracts; Triterpenes; Ursolic Acid | 2022 |
Ursolic Acid Enhances Myelin Repair in Adult Mice Brains and Stimulates Exhausted Oligodendrocyte Progenitors to Remyelinate.
Topics: Animals; Anti-Inflammatory Agents; Corpus Callosum; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Glial Fibrillary Acidic Protein; Gliosis; Inflammation; Interleukin-10; Mice; Mice, Inbred C57BL; Myelin Sheath; Oligodendrocyte Precursor Cells; Oligodendroglia; Tumor Necrosis Factor-alpha; Ursolic Acid | 2022 |
Preventive effect of ursolic acid derivative on particulate matter 2.5-induced chronic obstructive pulmonary disease involves suppression of lung inflammation.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Male; Mice; Oxidative Stress; Particulate Matter; Pneumonia; Protective Agents; Pulmonary Disease, Chronic Obstructive; Triterpenes; Ursolic Acid | 2020 |
Ursolic Acid Improves Monocrotaline-Induced Right Ventricular Remodeling by Regulating Metabolism.
Topics: Animals; Apoptosis; Carnitine O-Palmitoyltransferase; Cells, Cultured; Disease Models, Animal; Energy Metabolism; Fatty Acids; Fibrosis; Heart Ventricles; Hypertrophy, Right Ventricular; Male; Monocrotaline; Myocytes, Cardiac; PPAR alpha; Pulmonary Arterial Hypertension; Rats, Sprague-Dawley; Triterpenes; Ursolic Acid; Ventricular Function, Right; Ventricular Remodeling | 2020 |
Administration of ursolic acid to new-born pups prevents dietary fructose-induced non-alcoholic fatty liver disease in Sprague Dawley rats.
Topics: Adiposity; Animals; Dietary Carbohydrates; Disease Models, Animal; Female; Fructose; Humans; Liver; Male; Non-alcoholic Fatty Liver Disease; Protective Agents; Rats; Rats, Sprague-Dawley; Sex Factors; Triterpenes; Ursolic Acid; Weaning | 2021 |
Effects of Ursolic Acid on the Expression of Th1-Th2-related Cytokines in a Rat Model of Allergic Rhinitis After PM2.5 Exposure.
Topics: Animals; Cytokines; Disease Models, Animal; Female; Mice; Mice, Inbred BALB C; Nasal Mucosa; Ovalbumin; Particulate Matter; Rats; Rats, Sprague-Dawley; Rhinitis, Allergic; Th2 Cells; Triterpenes; Ursolic Acid | 2020 |
Ursolic acid reverses liver fibrosis by inhibiting interactive NOX4/ROS and RhoA/ROCK1 signalling pathways.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetophenones; Animals; Carbon Tetrachloride; Disease Models, Animal; Drugs, Chinese Herbal; Liver; Liver Cirrhosis; Male; Mice; Mice, Knockout; NADPH Oxidase 4; Reactive Oxygen Species; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Triterpenes; Ursolic Acid | 2020 |
Evaluation of ursolic acid derivatives with potential anti-Toxoplasma gondii activity.
Topics: Alanine Transaminase; Animals; Anti-Infective Agents; Aspartate Aminotransferases; Coccidiostats; Disease Models, Animal; Female; Glutathione; Liver; Malondialdehyde; Mice; Molecular Docking Simulation; Organ Size; Protein Kinase Inhibitors; Protein Kinases; Random Allocation; Spiramycin; Spleen; Toxoplasma; Toxoplasmosis; Toxoplasmosis, Animal; Triterpenes; Ursolic Acid | 2020 |
Neuroprotection of Rotenone-Induced Parkinsonism by Ursolic Acid in PD Mouse Model.
Topics: alpha-Synuclein; Animals; Anti-Inflammatory Agents; Antioxidants; Brain; Disease Models, Animal; Dopaminergic Neurons; Male; Mice; Neuroprotection; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Parkinsonian Disorders; Rotenone; Triterpenes; Ursolic Acid | 2020 |
Ursolic Acid Alleviates Mucus Secretion and Tissue Remodeling in Rat Model of Allergic Rhinitis After PM2.5 Exposure.
Topics: Animals; Disease Models, Animal; Mucus; Nasal Mucosa; Ovalbumin; Particulate Matter; Rats; Rhinitis, Allergic; Triterpenes; Ursolic Acid | 2021 |
Ursolic acid treatment suppresses cuprizone-induced demyelination and motor dysfunction via upregulation of IGF-1.
Topics: Administration, Oral; Animals; Cuprizone; Demyelinating Diseases; Disease Models, Animal; Gene Expression; Insulin-Like Growth Factor I; Mice; Motor Activity; Multiple Sclerosis; Triterpenes; Up-Regulation; Ursolic Acid | 2020 |
Ursolic acid ameliorates hypobaric hypoxia-induced skeletal muscle protein loss via upregulating Akt pathway: An experimental study using rat model.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Cyclooxygenase Inhibitors; Disease Models, Animal; Gene Expression Regulation; Hypoxia; Inflammation; Male; Muscle Proteins; Muscle, Skeletal; Oxidation-Reduction; Oxidative Stress; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Triterpenes; Up-Regulation; Ursolic Acid | 2021 |
Ursolic acid enhances stress resistance, reduces ROS accumulation and prolongs life span in C. elegans serotonin-deficient mutants.
Topics: Animals; Antioxidants; Caenorhabditis elegans; Depression; Disease Models, Animal; Hot Temperature; Longevity; Models, Molecular; Molecular Docking Simulation; Mutation; Naphthoquinones; Osmotic Pressure; Reactive Oxygen Species; Receptors, Serotonin; Serotonin; Stress, Physiological; Triterpenes; Ursolic Acid | 2021 |
Rosmarinic acid and ursolic acid alleviate deficits in cognition, synaptic regulation and adult hippocampal neurogenesis in an Aβ
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cinnamates; Cognition; Depsides; Disease Models, Animal; Doublecortin Protein; Gene Expression Regulation; Hippocampus; Male; Maze Learning; Mice, Inbred BALB C; Neurogenesis; Neurons; Neuroprotective Agents; Peptide Fragments; Rosmarinic Acid; Rosmarinus; Triterpenes; Ursolic Acid | 2021 |
Effect of miR-126 on the Proliferation and Migration of Vascular Smooth Muscle Cells in Aortic Aneurysm Mice Under PI3K/AKT/mTOR Signaling Pathway.
Topics: Animals; Aortic Aneurysm; Artificial Intelligence; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Humans; Liposomes; Male; Mice; Mice, Inbred BALB C; MicroRNAs; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Signal Transduction; Triterpenes; Ursolic Acid | 2021 |
Ursolic Acid Regulates Intestinal Microbiota and Inflammatory Cell Infiltration to Prevent Ulcerative Colitis.
Topics: Animals; Colitis, Ulcerative; Colon; Cytokines; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Microbiome; Humans; Intestinal Mucosa; Male; Mice; Signal Transduction; Triterpenes; Ursolic Acid | 2021 |
Radioprotective effect of ursolic acid in radiation-induced impairment of neurogenesis, learning and memory in adolescent BALB/c mouse.
Topics: Animals; Animals, Newborn; Basic Helix-Loop-Helix Transcription Factors; Conditioning, Psychological; Cyclooxygenase Inhibitors; Disease Models, Animal; Doublecortin Domain Proteins; Fear; Hindlimb Suspension; Hippocampus; Ki-67 Antigen; Learning Disabilities; Locomotion; Mice; Mice, Inbred BALB C; Microtubule-Associated Proteins; Nerve Tissue Proteins; Neurogenesis; Neuropeptides; Radiation Injuries, Experimental; Recognition, Psychology; Swimming; Triterpenes; Ursolic Acid | 2017 |
Anti-inflammatory activity of standardized dichloromethane extract of Salvia connivens on macrophages stimulated by LPS.
Topics: Animals; Anti-Inflammatory Agents; Cell Line; Chromatography, High Pressure Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; Edema; Flavonoids; Gas Chromatography-Mass Spectrometry; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Macrophage Activation; Macrophages; Magnetic Resonance Spectroscopy; Male; Methylene Chloride; Mice; Oleanolic Acid; Phytotherapy; Plant Components, Aerial; Plant Extracts; Plants, Medicinal; Salvia; Solvents; Tetradecanoylphorbol Acetate; Triterpenes; Tumor Necrosis Factor-alpha; Ursolic Acid | 2017 |
Anti-inflammatory effects of ursolic acid-3-acetate on human synovial fibroblasts and a murine model of rheumatoid arthritis.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Cells, Cultured; Collagen Type II; Cytokines; Disease Models, Animal; Fibroblasts; Humans; Immunoglobulin G; Inflammation Mediators; Male; Mice; Mice, Inbred DBA; Synovial Membrane; Th1 Cells; Th17 Cells; Triterpenes; Ursolic Acid | 2017 |
Ursolic acid affords antidepressant-like effects in mice through the activation of PKA, PKC, CAMK-II and MEK1/2.
Topics: Administration, Oral; Animals; Antidepressive Agents; Behavior, Animal; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cyclic AMP-Dependent Protein Kinases; Depression; Disease Models, Animal; Hindlimb Suspension; Male; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mice; Protein Kinase C; Signal Transduction; Triterpenes; Ursolic Acid | 2017 |
Efficacy of ursolic acid against Echinococcus granulosus in vitro and in a murine infection model.
Topics: Animals; Anthelmintics; Disease Models, Animal; Echinococcosis; Echinococcus granulosus; In Vitro Techniques; Larva; Mice; Microscopy, Electron; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Triterpenes; Ursolic Acid | 2018 |
Ursolic acid prevents angiotensin II-induced abdominal aortic aneurysm in apolipoprotein E-knockout mice.
Topics: ADAM17 Protein; Angiotensin II; Animals; Anti-Inflammatory Agents; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Cell Line; Cell Proliferation; Disease Models, Animal; Elastin; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice, Knockout, ApoE; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphorylation; Signal Transduction; STAT3 Transcription Factor; Triterpenes; Ursolic Acid; Vascular Remodeling; Wound Healing | 2018 |
Oral supplementation with ursolic acid ameliorates sepsis-induced acute kidney injury in a mouse model by inhibiting oxidative stress and inflammatory responses.
Topics: Acute Kidney Injury; Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Antioxidants; Disease Models, Animal; Inflammation; Male; Mice; Oxidative Stress; Sepsis; Triterpenes; Ursolic Acid | 2018 |
Ursolic Acid Attenuates Atherosclerosis in ApoE
Topics: Animals; Anti-Inflammatory Agents; Aorta; Apolipoproteins E; Atherosclerosis; Disease Models, Animal; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Inflammation; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myeloid Differentiation Factor 88; NF-kappa B; Reactive Oxygen Species; RNA, Small Interfering; Scavenger Receptors, Class E; Signal Transduction; Toll-Like Receptor 4; Triterpenes; Ursolic Acid | 2018 |
Synergistic action of ursolic acid and metformin in experimental model of insulin resistance and related behavioral alterations.
Topics: Acetylcholinesterase; Adiponectin; Animals; Behavior, Animal; Blood Pressure; Body Weight; Brain; Cognition; Corticosterone; Disease Models, Animal; Drug Synergism; Hypoglycemic Agents; Insulin Resistance; Liver; Male; Metformin; Mice; Organ Size; Oxidative Stress; Spleen; Triterpenes; Tumor Necrosis Factor-alpha; Ursolic Acid | 2018 |
Antihyperuricemic and xanthine oxidase inhibitory activities of Tribulus arabicus and its isolated compound, ursolic acid: In vitro and in vivo investigation and docking simulations.
Topics: Animals; Anti-Infective Agents; Disease Models, Animal; Gout; Humans; Hyperuricemia; Mice; Molecular Docking Simulation; Plant Extracts; Tribulus; Triterpenes; Ursolic Acid; Xanthine Oxidase | 2018 |
Effects of ursolic acid on sub-lesional muscle pathology in a contusion model of spinal cord injury.
Topics: Animals; Disease Models, Animal; Female; Gene Expression; Mice, Inbred C57BL; Motor Skills; Muscle Strength; Muscle, Skeletal; Organ Size; Protective Agents; Random Allocation; Spinal Cord Injuries; Triterpenes; Ursolic Acid | 2018 |
Ursolic acid alleviates inflammation and against diabetes‑induced nephropathy through TLR4‑mediated inflammatory pathway.
Topics: Animals; Diabetic Nephropathies; Disease Models, Animal; Drugs, Chinese Herbal; Gene Expression Regulation; Humans; Inflammation; Kidney; Mice; Myeloid Differentiation Factor 88; NF-kappa B; Oxidative Stress; Rats; Signal Transduction; Toll-Like Receptor 4; Triterpenes; Tumor Necrosis Factor-alpha; Ursolic Acid | 2018 |
Enhanced bioavailability and hepatoprotectivity of optimized ursolic acid-phospholipid complex.
Topics: Administration, Oral; Animals; Biological Availability; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Computer Simulation; Disease Models, Animal; Drug Compounding; Drug Liberation; Excipients; Half-Life; Humans; Liver; Male; Molecular Docking Simulation; Molecular Structure; Particle Size; Phospholipids; Protective Agents; Rats; Rats, Wistar; Solubility; Triterpenes; Ursolic Acid; X-Ray Diffraction | 2019 |
A modified diet does not ameliorate muscle pathology in a mouse model for Duchenne muscular dystrophy.
Topics: Amino Acids, Branched-Chain; Animals; Calcinosis; Cholecalciferol; Dietary Proteins; Disease Models, Animal; Dystrophin; Fibrosis; Humans; Male; Mice; Mice, Inbred DBA; Mice, Inbred mdx; Muscle, Skeletal; Muscular Dystrophy, Duchenne; Regeneration; Triterpenes; Ursolic Acid | 2019 |
DNA methylome and transcriptome alterations and cancer prevention by triterpenoid ursolic acid in UVB-induced skin tumor in mice.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Disease Models, Animal; DNA Damage; DNA Methylation; Epigenome; Humans; Mice; Neoplasm Proteins; Neoplasms, Radiation-Induced; Oxidative Stress; Signal Transduction; Skin; Skin Neoplasms; Transcriptome; Triterpenes; Ultraviolet Rays; Ursolic Acid | 2019 |
In vivo activity of ursolic and oleanolic acids during the acute phase of Trypanosoma cruzi infection.
Topics: Acute Disease; Administration, Oral; Animals; Anti-Infective Agents; Chagas Disease; Disease Models, Animal; Infusions, Parenteral; Interferon-gamma; Interleukin-10; Male; Melastomataceae; Mice; Mice, Inbred BALB C; Nitroimidazoles; Oleanolic Acid; Parasitemia; Random Allocation; Triterpenes; Trypanocidal Agents; Ursolic Acid | 2013 |
Anti-inflammatory and antioxidative effects of the methanolic extract of the aerial parts of Mitracarpus frigidus in established animal models.
Topics: Animals; Antioxidants; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Edema; Female; Inflammation; Inflammation Mediators; Kaempferols; Male; Mice; Naphthoquinones; Oxidative Stress; Phytotherapy; Plant Components, Aerial; Plant Extracts; Rats, Wistar; Rubiaceae; Rutin; Triterpenes; Ursolic Acid | 2014 |
Inhibition of human neutrophil elastase by pentacyclic triterpenes.
Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; Female; Glycine; Humans; Kinetics; Leukocyte Elastase; Mice, Inbred BALB C; Molecular Docking Simulation; Pentacyclic Triterpenes; Pneumonia; Proton Magnetic Resonance Spectroscopy; Saponins; Smoking; Sulfonamides; Triterpenes; Ursolic Acid | 2013 |
Ursolic acid inhibits nuclear factor-κB signaling in intestinal epithelial cells and macrophages, and attenuates experimental colitis in mice.
Topics: Animals; Cell Line; Colitis; Cytokines; Dextran Sulfate; Disease Models, Animal; Epithelial Cells; Humans; I-kappa B Proteins; Interleukin-10; Intestinal Mucosa; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Severity of Illness Index; Signal Transduction; Triterpenes; Ursolic Acid | 2014 |
Ursolic acid improves survival and attenuates lung injury in septic rats induced by cecal ligation and puncture.
Topics: Acute Lung Injury; Animals; Antineoplastic Agents, Phytogenic; Biomarkers; Cyclooxygenase 2; Cytokines; Dinoprostone; Disease Models, Animal; Drug Evaluation, Preclinical; Lung; Male; Malondialdehyde; Nitric Oxide; Nitric Oxide Synthase Type II; Peroxidase; Phytotherapy; Plant Extracts; Random Allocation; Rats, Sprague-Dawley; Sepsis; Triterpenes; Ursolic Acid | 2015 |
Protective effects of ursolic acid in an experimental model of liver fibrosis through Nrf2/ARE pathway.
Topics: Animals; Antioxidant Response Elements; Disease Models, Animal; Liver Cirrhosis; Male; Mice; NF-E2-Related Factor 2; Random Allocation; Signal Transduction; Triterpenes; Ursolic Acid | 2015 |
Ursolic acid alleviates early brain injury after experimental subarachnoid hemorrhage by suppressing TLR4-mediated inflammatory pathway.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Blood-Brain Barrier; Blotting, Western; Brain Edema; Disease Models, Animal; Immunohistochemistry; Male; Neurons; Rats, Sprague-Dawley; Signal Transduction; Subarachnoid Hemorrhage; Time Factors; Toll-Like Receptor 4; Triterpenes; Ursolic Acid | 2014 |
Downregulation of miR-21 is involved in direct actions of ursolic acid on the heart: implications for cardiac fibrosis and hypertrophy.
Topics: Animals; Cardiomegaly; Cardiomyopathies; Cell Proliferation; Cells, Cultured; Collagen; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Fibrosis; Male; Mice; MicroRNAs; Myocardium; Phosphorylation; Signal Transduction; Transfection; Triterpenes; Ursolic Acid; Ventricular Remodeling | 2015 |
Ursolic acid derivatives as bone anabolic agents targeted to tryptophan hydroxylase 1 (Tph-1).
Topics: Administration, Oral; Animals; Binding Sites; Bone Density Conservation Agents; Catalytic Domain; Disease Models, Animal; Down-Regulation; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Humans; Molecular Docking Simulation; Osteogenesis; Osteoporosis, Postmenopausal; Ovariectomy; Protein Binding; Protein Conformation; Rats; RNA, Messenger; Serotonin; Structure-Activity Relationship; Triterpenes; Tryptophan Hydroxylase; Ursolic Acid | 2015 |
The hypolipidemic effect of artesunate and ursolic acid in rats.
Topics: Animals; Artemisinins; Artesunate; Atorvastatin; Cholesterol; Disease Models, Animal; Heptanoic Acids; Hyperlipidemias; Hypolipidemic Agents; Pyrroles; Rats; Triglycerides; Triterpenes; Ursolic Acid | 2015 |
Macrophage Activation by Ursolic and Oleanolic Acids during Mycobacterial Infection.
Topics: Animals; Cell Culture Techniques; Disease Models, Animal; Dose-Response Relationship, Drug; Macrophage Activation; Macrophages; Mice; Mycobacterium tuberculosis; Nitric Oxide; Oleanolic Acid; Reactive Oxygen Species; Transforming Growth Factor beta1; Triterpenes; Tuberculosis; Tumor Necrosis Factor-alpha; Ursolic Acid | 2015 |
Ursolic acid exerts anti-cancer activity by suppressing vaccinia-related kinase 1-mediated damage repair in lung cancer cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Binding Sites; Catalytic Domain; Cell Line, Tumor; Disease Models, Animal; DNA Damage; Doxorubicin; Drug Synergism; Enzyme Activation; Humans; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; Models, Molecular; Molecular Conformation; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Interaction Domains and Motifs; Protein Serine-Threonine Kinases; Triterpenes; Ursolic Acid; Xenograft Model Antitumor Assays | 2015 |
Ursolic Acid Induces Apoptosis of Prostate Cancer Cells via the PI3K/Akt/mTOR Pathway.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Disease Models, Animal; Humans; Male; Mice, Nude; Phosphatidylinositol 3-Kinases; Phytotherapy; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Signal Transduction; TOR Serine-Threonine Kinases; Triterpenes; Ursolic Acid | 2015 |
The Effect of Ursolic Acid on Leishmania (Leishmania) amazonensis Is Related to Programed Cell Death and Presents Therapeutic Potential in Experimental Cutaneous Leishmaniasis.
Topics: Animals; Apoptosis; Cytokines; Disease Models, Animal; Female; Leishmania; Leishmaniasis, Cutaneous; Macrophages, Peritoneal; Male; Mice; Nitric Oxide; Oleanolic Acid; Plant Extracts; Triterpenes; Trypanocidal Agents; Ursolic Acid | 2015 |
Evaluation of Antitumor Activity of Long-Circulating and pH-Sensitive Liposomes Containing Ursolic Acid in Animal Models of Breast Tumor and Gliosarcoma.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; Female; Gliosarcoma; Humans; Hydrogen-Ion Concentration; Liposomes; Mammary Neoplasms, Animal; MCF-7 Cells; Mice; Mice, Nude; Rats; Triterpenes; Ursolic Acid | 2016 |
Amelioration of testosterone induced benign prostatic hyperplasia by Prunus species.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Chromatography, Gas; Chromatography, Thin Layer; Disease Models, Animal; Inflammation Mediators; Male; Oxidative Stress; Phytotherapy; Plant Bark; Plant Extracts; Plants, Medicinal; Prostate; Prostatic Hyperplasia; Prunus armeniaca; Prunus domestica; Prunus dulcis; Prunus persica; Rats, Wistar; Sitosterols; Testosterone; Triterpenes; Urological Agents; Ursolic Acid | 2016 |
Ursolic acid reduces the metalloprotease/anti-metalloprotease imbalance in cerebral ischemia and reperfusion injury.
Topics: Administration, Oral; Animals; Benzhydryl Compounds; Brain Ischemia; Disease Models, Animal; Epoxy Compounds; Male; Metalloproteases; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Triterpenes; Ursolic Acid | 2016 |
Effect of ursolic acid in attenuating chronic constriction injury-induced neuropathic pain in rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Constriction; Cytokines; Disease Models, Animal; Hyperalgesia; Inflammation; Male; Malondialdehyde; Neuralgia; Nitric Oxide; Oxidative Stress; Peroxidase; Protein Carbonylation; Rats; Sciatic Nerve; Spinal Cord; Superoxides; Triterpenes; Ursolic Acid | 2016 |
A novel co-drug of aspirin and ursolic acid interrupts adhesion, invasion and migration of cancer cells to vascular endothelium via regulating EMT and EGFR-mediated signaling pathways: multiple targets for cancer metastasis prevention and treatment.
Topics: Animals; Aspirin; Biomarkers; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Survival; Disease Models, Animal; Endothelium, Vascular; Epithelial-Mesenchymal Transition; ErbB Receptors; Female; Gene Expression; Heterografts; Humans; Mice; Models, Biological; Neoplasm Metastasis; Neoplasms; Rats; RNA, Messenger; Signal Transduction; Triterpenes; Ursolic Acid | 2016 |
Suppression of muscle wasting by the plant-derived compound ursolic acid in a model of chronic kidney disease.
Topics: Animals; Cell Line; Cytokines; Dexamethasone; Disease Models, Animal; Male; Mice, Inbred C57BL; Muscle Fibers, Skeletal; Muscle, Skeletal; Muscular Atrophy; Myostatin; Protein Biosynthesis; Proteolysis; Renal Insufficiency, Chronic; Triterpenes; Ursolic Acid | 2017 |
The anti-arthritic effect of ursolic acid on zymosan-induced acute inflammation and adjuvant-induced chronic arthritis models.
Topics: Acute Disease; Animals; Antirheumatic Agents; Arthritis, Experimental; Cell Movement; Chronic Disease; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Inflammation; Leukocytes; Mice; Mice, Inbred ICR; Oldenlandia; Pain; Plant Extracts; Rats; Rats, Sprague-Dawley; Triterpenes; Ursolic Acid; Zymosan | 2008 |
Ursolic acid attenuates D-galactose-induced inflammatory response in mouse prefrontal cortex through inhibiting AGEs/RAGE/NF-κB pathway activation.
Topics: Animals; Disease Models, Animal; Galactose; Glycation End Products, Advanced; Inflammation; Male; Mice; Mitogen-Activated Protein Kinases; NF-kappa B; Prefrontal Cortex; Signal Transduction; Triterpenes; Ursolic Acid | 2010 |
Ursolic acid induces allograft inflammatory factor-1 expression via a nitric oxide-related mechanism and increases neovascularization.
Topics: Angiogenesis Inducing Agents; Animals; Calcium-Binding Proteins; Cell Line; Disease Models, Animal; Endothelial Cells; Gene Expression; Hindlimb; Humans; Ischemia; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Microfilament Proteins; Neovascularization, Pathologic; Nitric Oxide; Nitric Oxide Synthase Type III; Triterpenes; Ursolic Acid | 2010 |
Inhibition of CXCR4/CXCL12 signaling axis by ursolic acid leads to suppression of metastasis in transgenic adenocarcinoma of mouse prostate model.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Movement; Chemokine CXCL12; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Transgenic; Neoplasm Metastasis; NF-kappa B; Prostatic Neoplasms; Proteasome Endopeptidase Complex; Receptors, CXCR4; Signal Transduction; Triterpenes; Ursolic Acid | 2011 |
Ursolic acid causes DNA-damage, p53-mediated, mitochondria- and caspase-dependent human endothelial cell apoptosis, and accelerates atherosclerotic plaque formation in vivo.
Topics: Animals; Apolipoproteins E; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-X Protein; Caspases; Cell Proliferation; Cells, Cultured; Disease Models, Animal; DNA Damage; Dose-Response Relationship, Drug; Down-Regulation; Human Umbilical Vein Endothelial Cells; Humans; Hyperlipidemias; Interleukin-5; Male; Mice; Mice, Knockout; Mitochondria; Plaque, Atherosclerotic; RNA Interference; Time Factors; Transfection; Triterpenes; Tumor Suppressor Protein p53; Ursolic Acid | 2011 |
Effects of Lecythis pisonis Camb. (Lecythidaceae) in a mouse model of pruritus.
Topics: Animals; Antipruritics; Behavior, Animal; Carrageenan; Cell Degranulation; Disease Models, Animal; Edema; Ethanol; Ether; Female; Lecythidaceae; Male; Mast Cells; Medicine, Traditional; Mice; Motor Activity; Oleanolic Acid; p-Methoxy-N-methylphenethylamine; Phytotherapy; Plant Extracts; Plant Leaves; Pruritus; Rats; Rats, Wistar; Solvents; South America; Triterpenes; Ursolic Acid | 2012 |
Antinociceptive and anti-inflammatory potential of extract and isolated compounds from the leaves of Salvia officinalis in mice.
Topics: Abietanes; Administration, Oral; Analgesics; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Inflammation; Lethal Dose 50; Mice; Motor Activity; Narcotic Antagonists; Oleanolic Acid; Pain; Pain Measurement; Plant Extracts; Plant Leaves; Plants, Medicinal; Salvia officinalis; Time Factors; Triterpenes; Ursolic Acid | 2012 |
Ursolic acid reduces prostate size and dihydrotestosterone level in a rat model of benign prostatic hyperplasia.
Topics: Animals; Dihydrotestosterone; Disease Models, Animal; Male; Organ Size; Prostate; Prostate-Specific Antigen; Prostatic Hyperplasia; Rats; Rats, Wistar; Triterpenes; Ursolic Acid | 2012 |
Suppression of AMF/PGI-mediated tumorigenic activities by ursolic acid in cultured hepatoma cells and in a mouse model.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Cell Adhesion; Cell Movement; Cell Proliferation; Cisplatin; Disease Models, Animal; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Flavones; Fluorescent Antibody Technique; Glucose-6-Phosphate Isomerase; Humans; Immunoprecipitation; Liver Neoplasms; Luciferases; Lung Neoplasms; Male; Matrix Metalloproteinase 3; Mice; Mice, Nude; Neovascularization, Pathologic; Oleanolic Acid; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; rhoA GTP-Binding Protein; Signal Transduction; Transforming Growth Factor beta; Triterpenes; Tumor Cells, Cultured; Ursolic Acid | 2013 |
[Effects of ursolic acid in ameliorating insulin resistance in liver of KKAy mice via peroxisome proliferator-activated receptors α and γ].
Topics: Adiponectin; Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Hypoglycemic Agents; Insulin Resistance; Liver; Mice; Mice, Inbred C57BL; PPAR alpha; PPAR gamma; Rosiglitazone; Thiazolidinediones; Triterpenes; Tumor Necrosis Factor-alpha; Ursolic Acid | 2012 |
Ursolic acid inhibits growth and metastasis of human colorectal cancer in an orthotopic nude mouse model by targeting multiple cell signaling pathways: chemosensitization with capecitabine.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; beta Catenin; Capecitabine; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Deoxycytidine; Disease Models, Animal; Drug Resistance, Neoplasm; Drug Synergism; ErbB Receptors; Fluorouracil; Humans; Ki-67 Antigen; Male; Mice; Mice, Nude; Neoplasm Metastasis; NF-kappa B; Platelet Endothelial Cell Adhesion Molecule-1; Signal Transduction; STAT3 Transcription Factor; Triterpenes; Tumor Suppressor Proteins; Ursolic Acid; Xenograft Model Antitumor Assays | 2012 |
Antiepileptic potential of ursolic acid stearoyl glucoside by GABA receptor stimulation.
Topics: Animals; Anticonvulsants; Convulsants; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Epilepsy; Glucosides; Isoniazid; Lantana; Phytotherapy; Plant Extracts; Plant Leaves; Receptors, GABA; Saponins; Seizures; Triterpenes; Ursolic Acid | 2012 |
Ursolic acid, a potential PPARγ agonist, suppresses ovalbumin-induced airway inflammation and Penh by down-regulating IL-5, IL-13, and IL-17 in a mouse model of allergic asthma.
Topics: Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Cell Count; Cell Line; Cyclosporine; Disease Models, Animal; Down-Regulation; Eosinophils; Female; GATA3 Transcription Factor; Hypersensitivity; Immunoglobulin E; Inflammation; Interleukin-13; Interleukin-17; Interleukin-5; Interleukins; Lung; Macrophages; Mice; Mice, Inbred BALB C; Ovalbumin; PPAR gamma; RNA, Messenger; STAT6 Transcription Factor; Th2 Cells; Triterpenes; Ursolic Acid | 2013 |
Ursolic acid attenuates lipopolysaccharide-induced acute lung injury in a mouse model.
Topics: Acute Lung Injury; Animals; Anti-Infective Agents; Cytokines; Disease Models, Animal; Female; Humans; Lipopolysaccharides; Lung; Mice; Mice, Inbred BALB C; Nitric Oxide; Shock, Septic; Treatment Outcome; Triterpenes; Ursolic Acid | 2013 |
Ursolic acid promotes the neuroprotection by activating Nrf2 pathway after cerebral ischemia in mice.
Topics: Animals; Brain Infarction; Brain Ischemia; Disease Models, Animal; Gene Expression Regulation; Heme Oxygenase-1; Malondialdehyde; Membrane Proteins; Mice; Mice, Knockout; Nerve Tissue Proteins; Neuroprotective Agents; NF-E2-Related Factor 2; NF-kappaB-Inducing Kinase; Protein Serine-Threonine Kinases; RNA, Messenger; Signal Transduction; Toll-Like Receptor 4; Triterpenes; Ursolic Acid | 2013 |
In vivo anti-nociceptive and anti-inflammatory effect of the two triterpenes, ursolic acid and 23-hydroxyursolic acid, from Cussonia bancoensis.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Araliaceae; Disease Models, Animal; Edema; Korea; Male; Medicine, East Asian Traditional; Mice; Mice, Inbred ICR; Molecular Structure; Pain; Plant Bark; Plant Extracts; Plant Leaves; Rats; Rats, Sprague-Dawley; Triterpenes; Ursolic Acid | 2003 |
Ursolic acid inhibits neointima formation in the rat carotid artery injury model.
Topics: Animals; Carotid Artery Injuries; Carotid Artery, Common; Cell Proliferation; Cells, Cultured; Cyclooxygenase Inhibitors; Disease Models, Animal; Follow-Up Studies; Hyperplasia; Immunohistochemistry; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Neovascularization, Pathologic; Proliferating Cell Nuclear Antigen; Rats; Rats, Sprague-Dawley; Triterpenes; Tubulin; Tunica Intima; Ursolic Acid; Vimentin | 2006 |
Protective effect of ursolic acid on ethanol-mediated experimental liver damage in rats.
Topics: Animals; Antioxidants; Body Weight; Chemoprevention; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Antagonism; Drug Therapy, Combination; Eating; Ethanol; Hepatocytes; Lipid Peroxidation; Liver Diseases, Alcoholic; Male; Rats; Rats, Wistar; Silymarin; Transaminases; Triterpenes; Ursolic Acid | 2006 |
Amelioration of adjuvant-induced arthritis by ursolic acid through altered Th1/Th2 cytokine production.
Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Cestrum; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Interferon-gamma; Interleukin-2; Mice; Mice, Inbred BALB C; Mycobacterium; Plant Leaves; Prednisolone; Th1 Cells; Th2 Cells; Triterpenes; Tumor Necrosis Factor-alpha; Ursolic Acid | 2006 |
Effect of triterpene acids of Eriobotrya japonica (Thunb.) Lindl. leaf on inflammatory cytokine and mediator induction from alveolar macrophages of chronic bronchitic rats.
Topics: Animals; Bronchitis, Chronic; Cell Nucleus; Cells, Cultured; Cytokines; Cytoplasm; Dinoprostone; Disease Models, Animal; Eriobotrya; Immunohistochemistry; Leukotriene B4; Macrophages, Alveolar; Male; Molecular Structure; NF-kappa B; Plant Extracts; Plant Leaves; Protein Subunits; Rats; Rats, Sprague-Dawley; Triterpenes; Ursolic Acid | 2007 |
In vitro and in vivo evaluation of betulinic acid as an antimalarial.
Topics: Animals; Antimalarials; Betulinic Acid; Disease Models, Animal; Euphorbiaceae; Malaria; Mice; Microbial Sensitivity Tests; Oleanolic Acid; Pentacyclic Triterpenes; Phytotherapy; Plant Extracts; Plant Roots; Plasmodium berghei; Plasmodium falciparum; Random Allocation; Structure-Activity Relationship; Triterpenes; Ursolic Acid | 1999 |