ursolic acid has been researched along with Colorectal Cancer in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (5.26) | 29.6817 |
| 2010's | 12 (63.16) | 24.3611 |
| 2020's | 6 (31.58) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, L; Liu, M; Meng, X; Ming, T; Ren, S; Sun, Q; Tang, S; Tao, Q; Xu, H; Yang, H; Zeng, S; Zhao, H | 1 |
| Li, H; Lin, J; Liu, H; Liu, X; Mao, Q; Min, J; Wu, M; Zeng, R; Zhang, C; Zheng, A | 1 |
| Lei, J; Liang, Y; Liu, M; Ming, T; Peng, Y; Ren, S; Tang, S; Tao, Q; Wang, M; Xu, H; Yang, H; Zhao, H | 1 |
| An, HM; Chen, L; Hu, B; Huang, XW; Li, M; Peng, X; Shen, KP; Wang, SS; Zheng, J- | 1 |
| An, HM; Chen, JF; Chen, L; Hu, B; Peng, X; Shen, KP; Wang, SS; Zheng, JL | 1 |
| Chen, L; He, M; Liu, ML; Ren, S; Sun, Q; Xu, HB; Yang, H; Zeng, S; Zhang, M; Zhao, H | 1 |
| Cai, Q; Chen, D; Lin, J; Peng, J; Wang, L; Zhang, L | 1 |
| Chen, H; Huang, L; Shen, R; Shi, H; Tao, J; Wang, T; Zhang, Y | 1 |
| Jung, JH; Kim, DS; Kim, K; Kim, SH; Park, JE; Shim, BS; Shin, EA | 1 |
| Chan, EWC; Hui, YW; Soon, CY; Tan, JBL; Wong, SK | 1 |
| Deng, W; Duan, C; He, N; Li, Q; Wang, Q; Wang, T; Wang, X; Yi, F; Zhu, L | 1 |
| Chen, Y; Hong, Z; Lin, J; Peng, J; Sferra, TJ; Shen, A; Wei, L | 1 |
| Chen, Y; Hong, Z; Lin, J; Peng, J; Sferra, TJ; Wei, L | 1 |
| Liu, Z; Shan, J; Xuan, Y; Zhang, Q; Zhang, S; Zhu, C | 1 |
| Fernandes-Ferreira, M; Lima, CF; Pereira-Wilson, C; Preto, A; Seruca, R; Xavier, CP | 1 |
| Aggarwal, BB; Kannappan, R; Prasad, S; Yadav, VR | 1 |
| Beneytout, JL; Cook-Moreau, J; Delage, C; Leger, DY; Liagre, B; Limami, Y; Mousseau, Y; Pinon, A; Simon, A | 1 |
| Beneytout, JL; Delage, C; Leger, DY; Liagre, B; Limami, Y; Pinault, E; Pinon, A; Simon, A | 1 |
| Aggarwal, BB; Baladandayuthapani, V; Deorukhkar, A; Diagaradjane, P; Guha, S; Kannappan, R; Krishnan, S; Prasad, S; Reuter, S; Sung, B; Wei, C; Yadav, VR | 1 |
1 review(s) available for ursolic acid and Colorectal Cancer
| Article | Year |
|---|---|
Ursolic acid: An overview on its cytotoxic activities against breast and colorectal cancer cells.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Proliferation; Colorectal Neoplasms; Drugs, Chinese Herbal; Female; Humans; Male; Triterpenes; Ursolic Acid | 2019 |
18 other study(ies) available for ursolic acid and Colorectal Cancer
| Article | Year |
|---|---|
Ursolic acid inhibits the activation of smoothened-independent non-canonical hedgehog pathway in colorectal cancer by suppressing AKT signaling cascade.
Topics: Animals; Cell Proliferation; Colorectal Neoplasms; Hedgehog Proteins; Humans; Oleanolic Acid; Proto-Oncogene Proteins c-akt; Signal Transduction; Triterpenes; Ursolic Acid; Zinc Finger Protein GLI1 | 2022 |
Self-assembled traditional Chinese nanomedicine modulating tumor immunosuppressive microenvironment for colorectal cancer immunotherapy.
Topics: Carcinogens; China; Colorectal Neoplasms; Humans; Immunologic Factors; Immunotherapy; Lentinan; Nanomedicine; Oleanolic Acid; Tumor Microenvironment; Ursolic Acid | 2022 |
Ursolic Acid Suppresses Colorectal Cancer by Down-Regulation of Wnt/β-Catenin Signaling Pathway Activity.
Topics: Animals; beta Catenin; Colorectal Neoplasms; Down-Regulation; Humans; Mice; Ursolic Acid; Wnt Signaling Pathway | 2023 |
Ursolic acid potentiated oxaliplatin to induce apoptosis in colorectal cancer RKO cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Down-Regulation; Drug Synergism; Humans; Oxaliplatin; Survivin; Triterpenes; Ursolic Acid; X-Linked Inhibitor of Apoptosis Protein | 2020 |
Ursolic acid induces apoptosis and anoikis in colorectal carcinoma RKO cells.
Topics: Anoikis; Apoptosis; Caspases; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; Epithelial-Mesenchymal Transition; Focal Adhesion Kinase 1; Humans; Reactive Oxygen Species; Signal Transduction; Triterpenes; Ursolic Acid | 2021 |
[Mechanism of ursolic acid in regulating colorectal cancer cell HCT116 autophagy through hedgehog signaling pathway].
Topics: Apoptosis; Autophagy; Cell Line, Tumor; Colorectal Neoplasms; Hedgehog Proteins; Humans; Signal Transduction; Triterpenes; Ursolic Acid | 2021 |
Comparative proteomics-network analysis of proteins responsible for ursolic acid-induced cytotoxicity in colorectal cancer cells.
Topics: Apoptosis; Calreticulin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chaperonin 60; Colorectal Neoplasms; Electrophoresis, Gel, Two-Dimensional; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Heat-Shock Proteins; HSP27 Heat-Shock Proteins; Humans; Membrane Glycoproteins; Mitochondrial Proteins; Mitochondrial Proton-Translocating ATPases; Molecular Chaperones; Neoplasm Proteins; Protein Folding; Proteomics; Signal Transduction; Triterpenes; Ursolic Acid | 2017 |
Ursolic acid enhances the therapeutic effects of oxaliplatin in colorectal cancer by inhibition of drug resistance.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Drug Resistance, Neoplasm; Drug Synergism; Humans; Mice; Organoplatinum Compounds; Oxaliplatin; Reactive Oxygen Species; Treatment Outcome; Triterpenes; Ursolic Acid; Xenograft Model Antitumor Assays | 2018 |
Ursolic Acid Induces Apoptosis in Colorectal Cancer Cells Partially via Upregulation of MicroRNA-4500 and Inhibition of JAK2/STAT3 Phosphorylation.
Topics: Apoptosis; Colorectal Neoplasms; HCT116 Cells; HT29 Cells; Humans; Janus Kinase 2; MicroRNAs; Phosphorylation; Poly(ADP-ribose) Polymerases; Signal Transduction; STAT3 Transcription Factor; Triterpenes; Up-Regulation; Ursolic Acid | 2018 |
Ursolic Acid Inhibits Tumor Growth via Epithelial-to-Mesenchymal Transition in Colorectal Cancer Cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Epithelial-Mesenchymal Transition; Humans; Triterpenes; Ursolic Acid | 2019 |
Ursolic acid promotes colorectal cancer cell apoptosis and inhibits cell proliferation via modulation of multiple signaling pathways.
Topics: Animals; Apoptosis; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Mice; Proto-Oncogene Proteins c-akt; Signal Transduction; STAT3 Transcription Factor; Triterpenes; Ursolic Acid; Xenograft Model Antitumor Assays | 2013 |
Ursolic acid inhibits colorectal cancer angiogenesis through suppression of multiple signaling pathways.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Cell Movement; Cell Proliferation; Chick Embryo; Chorioallantoic Membrane; Colorectal Neoplasms; Human Umbilical Vein Endothelial Cells; Humans; Immunoenzyme Techniques; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neovascularization, Pathologic; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Triterpenes; Ursolic Acid; Xenograft Model Antitumor Assays | 2013 |
Ursolic acid synergistically enhances the therapeutic effects of oxaliplatin in colorectal cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Colorectal Neoplasms; Drug Synergism; Female; Humans; Mice; Mice, Nude; Neoplasm Proteins; Organoplatinum Compounds; Oxaliplatin; Triterpenes; Ursolic Acid; Xenograft Model Antitumor Assays | 2016 |
Luteolin, quercetin and ursolic acid are potent inhibitors of proliferation and inducers of apoptosis in both KRAS and BRAF mutated human colorectal cancer cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Extracellular Signal-Regulated MAP Kinases; Humans; In Situ Nick-End Labeling; Luteolin; Mutation; Proto-Oncogene Proteins; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins p21(ras); Quercetin; ras Proteins; Triterpenes; Ursolic Acid | 2009 |
Ursolic acid, a pentacyclin triterpene, potentiates TRAIL-induced apoptosis through p53-independent up-regulation of death receptors: evidence for the role of reactive oxygen species and JNK.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Caco-2 Cells; Cell Survival; Colorectal Neoplasms; Down-Regulation; Drug Synergism; Humans; MAP Kinase Kinase 4; Mice; Mice, Nude; Neoplasm Transplantation; Reactive Oxygen Species; Receptors, TNF-Related Apoptosis-Inducing Ligand; TNF-Related Apoptosis-Inducing Ligand; Triterpenes; Tumor Necrosis Factor Decoy Receptors; Tumor Suppressor Protein p53; Up-Regulation; Ursolic Acid; Xenograft Model Antitumor Assays | 2011 |
HT-29 colorectal cancer cells undergoing apoptosis overexpress COX-2 to delay ursolic acid-induced cell death.
Topics: Apoptosis; Colorectal Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Resistance, Neoplasm; HCT116 Cells; HT29 Cells; Humans; Nitrobenzenes; p38 Mitogen-Activated Protein Kinases; RNA, Small Interfering; Sulfonamides; Triterpenes; Ursolic Acid | 2011 |
The P2Y2/Src/p38/COX-2 pathway is involved in the resistance to ursolic acid-induced apoptosis in colorectal and prostate cancer cells.
Topics: Adenosine Triphosphate; Apoptosis; Arachidonic Acid; Colorectal Neoplasms; Cyclooxygenase 2; Female; Gene Expression Regulation, Neoplastic; Group II Phospholipases A2; HT29 Cells; Humans; Male; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Prostatic Neoplasms; Receptors, Purinergic P2Y2; Signal Transduction; src-Family Kinases; Triterpenes; Ursolic Acid | 2012 |
Ursolic acid inhibits growth and metastasis of human colorectal cancer in an orthotopic nude mouse model by targeting multiple cell signaling pathways: chemosensitization with capecitabine.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; beta Catenin; Capecitabine; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Deoxycytidine; Disease Models, Animal; Drug Resistance, Neoplasm; Drug Synergism; ErbB Receptors; Fluorouracil; Humans; Ki-67 Antigen; Male; Mice; Mice, Nude; Neoplasm Metastasis; NF-kappa B; Platelet Endothelial Cell Adhesion Molecule-1; Signal Transduction; STAT3 Transcription Factor; Triterpenes; Tumor Suppressor Proteins; Ursolic Acid; Xenograft Model Antitumor Assays | 2012 |