Page last updated: 2024-08-24

ursolic acid and Cancer of Colon

ursolic acid has been researched along with Cancer of Colon in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (44.44)29.6817
2010's4 (44.44)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Paduch, R; Piet, M1
Chen, W; Cheng, J; Deng, W; Fu, L; Guo, W; Huang, W; Liu, L; Qiu, H; Shi, D; Tian, Y; Wang, J; Zhang, X1
Jou, D; Lin, J; Lin, L; Lü, J; Wang, W; Zhang, C; Zhao, C1
Huang, JJ; Shan, JZ; Xuan, YY; Zhang, Q1
Kim, ST; Kim, SY; Koh, SJ; Nam, WS; Park, JW; Park, KM; Tak, JK1
Apan, TR; Chávez, IO; Martínez-Vázquez, M1
Andersson, D; Cheng, Y; Duan, RD1
Araújo, FR; Castro, MB; Cunha, WR; Furtado, MA; Furtado, RA; Oliveira, WL; Rodrigues, EP; Tavares, DC1
Guo, WJ; Li, J; Yang, QY1

Other Studies

9 other study(ies) available for ursolic acid and Cancer of Colon

ArticleYear
Ursolic and oleanolic acids in combination therapy inhibit migration of colon cancer cells through down-regulation of the uPA/uPAR-dependent MMPs pathway.
    Chemico-biological interactions, 2022, Dec-01, Volume: 368

    Topics: Cadherins; Colonic Neoplasms; Down-Regulation; Humans; Irinotecan; Matrix Metalloproteinase 2; Oleanolic Acid; Ursolic Acid

2022
Ursolic acid simultaneously targets multiple signaling pathways to suppress proliferation and induce apoptosis in colon cancer cells.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Acetylation; Antineoplastic Agents; Apoptosis; Caspases; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colonic Neoplasms; Cyclooxygenase 2; Cytochromes c; Dinoprostone; E1A-Associated p300 Protein; Humans; NF-kappa B; Protein Transport; Signal Transduction; Time Factors; Triterpenes; Ursolic Acid

2013
Ursolic acid inhibits the growth of colon cancer-initiating cells by targeting STAT3.
    Anticancer research, 2013, Volume: 33, Issue:10

    Topics: Animals; Antineoplastic Agents, Phytogenic; Caspase 3; Cell Proliferation; Cell Survival; Colonic Neoplasms; Enzyme Activation; Female; HCT116 Cells; HT29 Cells; Humans; Interleukin-6; Mice; Mice, Nude; Neoplastic Stem Cells; Phosphorylation; Protein Processing, Post-Translational; Spheroids, Cellular; STAT3 Transcription Factor; Triterpenes; Tumor Burden; Ursolic Acid; Xenograft Model Antitumor Assays

2013
Ursolic acid sensitized colon cancer cells to chemotherapy under hypoxia by inhibiting MDR1 through HIF-1α.
    Journal of Zhejiang University. Science. B, 2016, Volume: 17, Issue:9

    Topics: Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Cell Survival; Colonic Neoplasms; Cycloheximide; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Fluorouracil; Human Umbilical Vein Endothelial Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Neovascularization, Pathologic; Organoplatinum Compounds; Oxaliplatin; Real-Time Polymerase Chain Reaction; RNA, Small Interfering; Triterpenes; Ursolic Acid; Vascular Endothelial Growth Factor A

2016
Sensitization of ionizing radiation-induced apoptosis by ursolic acid.
    Free radical research, 2012, Volume: 46, Issue:3

    Topics: Adenocarcinoma; Animals; Apoptosis; Cell Line, Tumor; Chemoradiotherapy; Colonic Neoplasms; Combined Modality Therapy; DNA Fragmentation; DNA, Neoplasm; Drug Screening Assays, Antitumor; Lipid Peroxidation; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Oxidation-Reduction; Prostatic Neoplasms; Radiation-Sensitizing Agents; Triterpenes; Ursolic Acid

2012
Cytotoxic activity and effect on nitric oxide production of tirucallane-type triterpenes.
    The Journal of pharmacy and pharmacology, 2005, Volume: 57, Issue:9

    Topics: Anacardiaceae; Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Death; Cell Line, Tumor; Central Nervous System Neoplasms; Colonic Neoplasms; Drug Screening Assays, Antitumor; Female; Hexanes; Humans; Leukemia; Lipopolysaccharides; Macrophages, Peritoneal; Male; Medicine, Traditional; Mexico; Mice; Nitric Oxide; Plant Extracts; Prostatic Neoplasms; Rhodamines; Triterpenes; Ursolic Acid

2005
Ursolic acid inhibits the formation of aberrant crypt foci and affects colonic sphingomyelin hydrolyzing enzymes in azoxymethane-treated rats.
    Journal of cancer research and clinical oncology, 2008, Volume: 134, Issue:1

    Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Azoxymethane; Carcinogens; Colon; Colonic Neoplasms; Dose-Response Relationship, Drug; Female; Intestinal Mucosa; Rats; Rats, Sprague-Dawley; Sphingomyelin Phosphodiesterase; Sphingomyelins; Treatment Outcome; Triterpenes; Tumor Cells, Cultured; Ursolic Acid

2008
Ursolic acid and oleanolic acid suppress preneoplastic lesions induced by 1,2-dimethylhydrazine in rat colon.
    Toxicologic pathology, 2008, Volume: 36, Issue:4

    Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Colonic Neoplasms; Male; Melastomataceae; Oleanolic Acid; Plant Components, Aerial; Precancerous Conditions; Rats; Rats, Wistar; Triterpenes; Ursolic Acid

2008
Effects of ursolic acid and oleanolic acid on human colon carcinoma cell line HCT15.
    World journal of gastroenterology, 2002, Volume: 8, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Cell Cycle; Cell Division; Cell Survival; Colonic Neoplasms; Humans; Oleanolic Acid; Triterpenes; Tumor Cells, Cultured; Ursolic Acid

2002