Page last updated: 2024-08-24

ursolic acid and Breast Cancer

ursolic acid has been researched along with Breast Cancer in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (13.16)29.6817
2010's25 (65.79)24.3611
2020's8 (21.05)2.80

Authors

AuthorsStudies
Aliev, G; Arunasree, KM; Bishayee, A; Dhananjaya, BL; Dharmapuri, G; Pedada, SR; Philip, GH; Putta, S; Rangaiah, G; Tambade, PJ; Yarla, NS1
Chang, S; Ma, H; Su, Y; Wen, J1
Jia, A; Jiang, H; Luo, H; Sun, B; Wang, Z; Zhang, P1
Li, G; Liu, S; Luo, F; Mei, Y; Tang, D; Xie, Y; Xue, Y; Yang, J; Zhao, J1
Balnytė, K; Corcelle-Termeau, E; Dinant, C; Fogde, DL; Holland, LKK; Jäättelä, M; Maeda, K; Pereira-Wilson, C; Stahl-Meyer, K; Xavier, CPR1
Cheng, CW; Hung, YT; Lee, HJ; Liao, WL; Liu, YF; Shen, CY; Shieh, JC; Ying, TH1
Gong, ES; Li, T; Liu, RH; Zhang, X1
Feng, B; Li, J; Tian, T; Yu, J; Zhang, X; Zhang, Y; Zhao, C; Zhao, L1
Dharmarajan, A; Gamit, N; Mandal, S; Varier, L; Warrier, S1
Adamczyk-Grochala, J; Bednarz, D; Lewinska, A; Wnuk, M1
Jaman, MS; Sayeed, MA1
Abbasi, BA; Ahmad, R; Alam, MM; Ali, B; Badshah, H; Iqbal, J; Kanwal, S; Khalil, AT; Mahmood, T; Shah, SA1
Cheng, G; Liu, S; Liu, Z; Pi, Z; Song, F; Zong, L1
Chan, EWC; Hui, YW; Soon, CY; Tan, JBL; Wong, SK1
Inn, KS; Jang, DS; Jo, SJ; Kim, HI; Kim, HJ; Kim, JE; Lee, CM; Lee, NR; Quan, FS1
Efferth, T; Kadioglu, O1
Bañuelos-García, JI; Carranza-Rosales, P; Carranza-Torres, IE; Coronado-Martínez, C; Guzmán-Delgado, NE; Morán-Martínez, J; Viveros-Valdez, E1
Wang, CQ; Wang, HT1
González-Vallinas, M; Ramírez de Molina, A; Reglero, G1
Balvay, D; Braga, FC; Cassali, GD; Ferreira, Ê; Ferreira, LA; Garofalakis, A; Leite, EA; Lopes, SC; Oliveira, MC; Rocha, TG; Tavitian, B; Veloso, ES1
Li, T; Liu, RH; Tian, JX; Xi, P; Yin, R1
Bai, H; Cai, J; Chen, ZW; Huang, L; Jiang, J; Jin, H; Li, L; Li, T; Pi, J; Shao, M; Wang, X; Yang, F; Yang, P; Zhu, H1
Adamczyk-Grochala, J; Deregowska, A; Kwasniewicz, E; Lewinska, A; Wnuk, M1
Aligiannis, N; Kassi, E; Moutsatsou, P; Papoutsi, Z; Pratsinis, H; Sourlingas, TG; Spiliotaki, M1
Jadranin, M; Juranić, ZD; Konić-Ristić, A; Menković, N; Savikin, K; Stanojković, TP; Zdunić, G1
Wu, CH; Yeh, CT; Yen, GC1
De Angel, RE; Glickman, RD; Hursting, SD; Perkins, SN; Smith, SM1
Ren, TN; Wang, JS; Xi, T1
Ahmed, S; Bishayee, A; Brankov, N; Perloff, M1
Choi, HS; Choi, I; Kim, KH; Ko, SG; Seo, HS; Shin, YC1
Andò, S; Barone, I; Bonofiglio, D; Catalano, S; Gelsomino, L; Giordano, C; Gu, G; Menichini, F; Statti, G1
Bid, HK; Chakravarti, B; Konwar, R; Maurya, R; Rajendran, SM; Siddiqui, JA; Yadav, PP1
He, X; Hu, H; Wang, Y; Zhang, Z1
Dong, Y; Fan, L; Guo, X; Hu, H; Ye, M; Yin, S; Zhao, C1
Li, Y; Lü, J; Ou, H; Zhang, G; Zhang, W1
Apan, TR; Chávez, IO; Martínez-Vázquez, M1
Lu, YY; Lv, JC; Ou, HJ; Zhang, GP1
He, X; Liu, RH1

Reviews

6 review(s) available for ursolic acid and Breast Cancer

ArticleYear
Ellagic acid, sulforaphane, and ursolic acid in the prevention and therapy of breast cancer: current evidence and future perspectives.
    Breast cancer (Tokyo, Japan), 2018, Volume: 25, Issue:5

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Biological Availability; Breast Neoplasms; Ellagic Acid; Female; Humans; Isothiocyanates; Sulfoxides; Triterpenes; Ursolic Acid

2018
Ursolic acid a promising candidate in the therapeutics of breast cancer: Current status and future implications.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 108

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Proliferation; Female; Humans; Neovascularization, Pathologic; Signal Transduction; Triterpenes; Ursolic Acid

2018
Ursolic acid: An overview on its cytotoxic activities against breast and colorectal cancer cells.
    Journal of integrative medicine, 2019, Volume: 17, Issue:3

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Proliferation; Colorectal Neoplasms; Drugs, Chinese Herbal; Female; Humans; Male; Triterpenes; Ursolic Acid

2019
Rosemary (Rosmarinus officinalis L.) Extract as a Potential Complementary Agent in Anticancer Therapy.
    Nutrition and cancer, 2015, Volume: 67, Issue:8

    Topics: Abietanes; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Breast Neoplasms; Cinnamates; Depsides; Drug Interactions; Europe; Humans; Neoplasms; Phytotherapy; Plant Extracts; Rosmarinic Acid; Rosmarinus; Triterpenes; United States; United States Food and Drug Administration; Ursolic Acid

2015
Ursolic acid, a potential anticancer compound for breast cancer therapy.
    Critical reviews in food science and nutrition, 2018, Mar-04, Volume: 58, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Fruit; Humans; Phytochemicals; Signal Transduction; Triterpenes; Ursolic Acid; Vegetables

2018
Triterpenoids as potential agents for the chemoprevention and therapy of breast cancer.
    Frontiers in bioscience (Landmark edition), 2011, 01-01, Volume: 16, Issue:3

    Topics: Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Chemoprevention; Glycosides; Humans; Mice; Oleanolic Acid; Triterpenes; Ursolic Acid

2011

Other Studies

32 other study(ies) available for ursolic acid and Breast Cancer

ArticleYear
Synthesis of new secretory phospholipase A2-inhibitory indole containing isoxazole derivatives as anti-inflammatory and anticancer agents.
    European journal of medicinal chemistry, 2016, Apr-13, Volume: 112

    Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Humans; Indoles; Isoxazoles; Male; Mice; Models, Molecular; Phospholipases A2, Secretory; Prostatic Neoplasms; Rats, Wistar

2016
Microfluidic platform for studying the anti-cancer effect of ursolic acid on tumor spheroid.
    Electrophoresis, 2022, Volume: 43, Issue:13-14

    Topics: Breast Neoplasms; Female; Humans; Microfluidics; Spheroids, Cellular; Triterpenes; Ursolic Acid

2022
Ursolic Acid Enhances the Sensitivity of MCF-7 and MDA-MB-231 Cells to Epirubicin by Modulating the Autophagy Pathway.
    Molecules (Basel, Switzerland), 2022, May-25, Volume: 27, Issue:11

    Topics: Apoptosis; Autophagy; Beclin-1; Breast Neoplasms; Cell Line, Tumor; Epirubicin; Female; Humans; MCF-7 Cells; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Triterpenes; Ursolic Acid

2022
Ursolic acid augments the chemosensitivity of drug-resistant breast cancer cells to doxorubicin by AMPK-mediated mitochondrial dysfunction.
    Biochemical pharmacology, 2022, Volume: 205

    Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Apoptosis; Breast Neoplasms; Doxorubicin; Drug Resistance, Neoplasm; Female; Glucose Transporter Type 1; Humans; MCF-7 Cells; Mitochondria; Reactive Oxygen Species; TOR Serine-Threonine Kinases; Triterpenes; Ursolic Acid

2022
Ursolic Acid Impairs Cellular Lipid Homeostasis and Lysosomal Membrane Integrity in Breast Carcinoma Cells.
    Cells, 2022, 12-16, Volume: 11, Issue:24

    Topics: Breast Neoplasms; Female; Homeostasis; Humans; Lipids; Lysosomes; Ursolic Acid

2022
Inhibitory Effects of Ursolic Acid on the Stemness and Progression of Human Breast Cancer Cells by Modulating Argonaute-2.
    International journal of molecular sciences, 2022, Dec-26, Volume: 24, Issue:1

    Topics: Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Neoplastic Stem Cells; Phosphatidylinositol 3-Kinases; Triterpenes; Ursolic Acid

2022
Antiproliferative Activity of Ursolic Acid in MDA-MB-231 Human Breast Cancer Cells through Nrf2 Pathway Regulation.
    Journal of agricultural and food chemistry, 2020, Jul-15, Volume: 68, Issue:28

    Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Growth Inhibitors; Humans; Kelch-Like ECH-Associated Protein 1; NF-E2-Related Factor 2; Oxidative Stress; Triterpenes; Ursolic Acid

2020
The Novel Synthetic Triterpene Methyl 3β-O-[4-(2-Aminoethylamino)-4-oxo-butyryl]olean-12-ene-28-oate Inhibits Breast Tumor Cell Growth in Vitro and in Vivo.
    Chemical & pharmaceutical bulletin, 2020, Volume: 68, Issue:10

    Topics: A549 Cells; Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Caspase 3; Cell Proliferation; Cytochromes c; Drug Screening Assays, Antitumor; Female; HeLa Cells; Humans; MCF-7 Cells; Mice, Inbred BALB C; Mice, Nude; Oleanolic Acid; Proto-Oncogene Proteins c-bcl-2; Triterpenes; Ursolic Acid

2020
Inhibition of breast cancer stem-like cells by a triterpenoid, ursolic acid, via activation of Wnt antagonist, sFRP4 and suppression of miRNA-499a-5p.
    Life sciences, 2021, Jan-15, Volume: 265

    Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; MicroRNAs; Neoplastic Stem Cells; Proto-Oncogene Proteins; Triterpenes; Up-Regulation; Ursolic Acid; Wnt Signaling Pathway

2021
Phytochemical-induced nucleolar stress results in the inhibition of breast cancer cell proliferation.
    Redox biology, 2017, Volume: 12

    Topics: Antineoplastic Agents, Phytogenic; Betulinic Acid; Breast Neoplasms; Cell Line, Tumor; Cell Nucleolus; Cell Proliferation; Cell Survival; Female; Gene Expression Regulation, Neoplastic; Humans; Isothiocyanates; MCF-7 Cells; Pentacyclic Triterpenes; Protein Carbonylation; Sulfoxides; Superoxides; Triterpenes; Ursolic Acid

2017
Reversal of multidrug resistance in breast cancer cells by a combination of ursolic acid with doxorubicin.
    Journal of pharmaceutical and biomedical analysis, 2019, Feb-20, Volume: 165

    Topics: Animals; Antibiotics, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Chromatography, High Pressure Liquid; Dogs; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Female; Humans; Madin Darby Canine Kidney Cells; MCF-7 Cells; Tandem Mass Spectrometry; Triterpenes; Ursolic Acid

2019
Inhibition of estrogen signaling through depletion of estrogen receptor alpha by ursolic acid and betulinic acid from Prunella vulgaris var. lilacina.
    Biochemical and biophysical research communications, 2014, Aug-22, Volume: 451, Issue:2

    Topics: Betulinic Acid; Breast Neoplasms; Cell Line, Tumor; Drug Evaluation, Preclinical; Estrogen Receptor alpha; Estrogen Receptor Modulators; Estrogens; Female; Humans; Male; MCF-7 Cells; Neoplasm Proteins; Pentacyclic Triterpenes; Phytotherapy; Plants, Medicinal; Promoter Regions, Genetic; Prostate-Specific Antigen; Prostatic Neoplasms; Prunella; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Triterpenes; Ursolic Acid

2014
Pharmacogenomic Characterization of Cytotoxic Compounds from Salvia officinalis in Cancer Cells.
    Journal of natural products, 2015, Apr-24, Volume: 78, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Breast Neoplasms; Drug Resistance, Neoplasm; Genes, erbB-1; Humans; Leupeptins; Molecular Structure; NF-kappa B; Oleanolic Acid; Pharmacogenetics; Plants, Medicinal; Salvia officinalis; Signal Transduction; Triterpenes; Ursolic Acid

2015
Organotypic culture of breast tumor explants as a multicellular system for the screening of natural compounds with antineoplastic potential.
    BioMed research international, 2015, Volume: 2015

    Topics: Adult; Breast Neoplasms; Caffeic Acids; Cinnamates; Depsides; Drug Screening Assays, Antitumor; Female; Humans; Middle Aged; Rosmarinic Acid; Tissue Culture Techniques; Triterpenes; Ursolic Acid

2015
[27-O-(E)-p-coumaric acyl ursolic acid via JNK/SAPK signal pathway regulates apoptosis of human breast cancer MDA-MB-231 cell line].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2015, Volume: 40, Issue:4

    Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Drugs, Chinese Herbal; Female; Humans; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase 8; Signal Transduction; Triterpenes; Ursolic Acid

2015
Evaluation of Antitumor Activity of Long-Circulating and pH-Sensitive Liposomes Containing Ursolic Acid in Animal Models of Breast Tumor and Gliosarcoma.
    Integrative cancer therapies, 2016, Volume: 15, Issue:4

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Disease Models, Animal; Female; Gliosarcoma; Humans; Hydrogen-Ion Concentration; Liposomes; Mammary Neoplasms, Animal; MCF-7 Cells; Mice; Mice, Nude; Rats; Triterpenes; Ursolic Acid

2016
Folate-Chitosan Nanoparticles Loaded with Ursolic Acid Confer Anti-Breast Cancer Activities in vitro and in vivo.
    Scientific reports, 2016, 07-29, Volume: 6

    Topics: Animals; Breast Neoplasms; Cell Proliferation; Cell Survival; Chitosan; Female; Folic Acid; Humans; MCF-7 Cells; Membrane Potential, Mitochondrial; Mice; Mitochondria; Nanoparticles; Triterpenes; Ursolic Acid; Xenograft Model Antitumor Assays

2016
Ursolic acid-mediated changes in glycolytic pathway promote cytotoxic autophagy and apoptosis in phenotypically different breast cancer cells.
    Apoptosis : an international journal on programmed cell death, 2017, Volume: 22, Issue:6

    Topics: Apoptosis; Autophagy; Betulinic Acid; Breast Neoplasms; Cell Line, Tumor; DNA Damage; Extracellular Signal-Regulated MAP Kinases; Female; G1 Phase Cell Cycle Checkpoints; Glycolysis; Humans; Models, Biological; Nitrosation; Oxidative Stress; Pentacyclic Triterpenes; Phenotype; Signal Transduction; Triterpenes; Ursolic Acid

2017
Ursolic acid triggers apoptosis and Bcl-2 downregulation in MCF-7 breast cancer cells.
    Cancer investigation, 2009, Volume: 27, Issue:7

    Topics: Active Transport, Cell Nucleus; Adenocarcinoma; Antineoplastic Agents; Apoptosis; Binding, Competitive; Breast Neoplasms; Cell Line, Tumor; Dexamethasone; Down-Regulation; Drug Screening Assays, Antitumor; Female; Gene Expression Regulation, Neoplastic; Genes, bcl-2; HeLa Cells; Humans; Mifepristone; Neoplasm Proteins; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Receptors, Glucocorticoid; Transcription Factor AP-1; Transcription, Genetic; Triamcinolone; Triterpenes; Ursolic Acid

2009
Cytotoxic and cell cycle effects induced by two herbal extracts on human cervix carcinoma and human breast cancer cell lines.
    Journal of medicinal food, 2010, Volume: 13, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cinnamates; Depsides; Female; HeLa Cells; Humans; Inhibitory Concentration 50; Magnoliopsida; Phenols; Phytotherapy; Plant Extracts; Rosmarinic Acid; Tannins; Triterpenes; Ursolic Acid; Uterine Cervical Neoplasms

2010
Ursolic acid, a naturally occurring triterpenoid, suppresses migration and invasion of human breast cancer cells by modulating c-Jun N-terminal kinase, Akt and mammalian target of rapamycin signaling.
    Molecular nutrition & food research, 2010, Volume: 54, Issue:9

    Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Proliferation; Female; Humans; JNK Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; NF-kappa B; Osmolar Concentration; Phosphorylation; Protein Kinase Inhibitors; Protein Transport; Proto-Oncogene Proteins c-akt; Signal Transduction; Time Factors; TOR Serine-Threonine Kinases; Triterpenes; Ursolic Acid

2010
Antitumor effects of ursolic acid in a mouse model of postmenopausal breast cancer.
    Nutrition and cancer, 2010, Volume: 62, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Biomarkers; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C57BL; Mice, Transgenic; Ovariectomy; Postmenopause; Random Allocation; Signal Transduction; Triterpenes; Tumor Burden; Ursolic Acid

2010
Ursolic acid induces apoptosis by suppressing the expression of FoxM1 in MCF-7 human breast cancer cells.
    Medical oncology (Northwood, London, England), 2012, Volume: 29, Issue:1

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Cyclin-Dependent Kinase 4; Female; Forkhead Box Protein M1; Forkhead Transcription Factors; Gene Expression; Humans; Reverse Transcriptase Polymerase Chain Reaction; Triterpenes; Ursolic Acid

2012
Induction of apoptotic cell death by ursolic acid through mitochondrial death pathway and extrinsic death receptor pathway in MDA-MB-231 cells.
    Archives of pharmacal research, 2011, Volume: 34, Issue:8

    Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Breast Neoplasms; Caspases; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cysteine Proteinase Inhibitors; Cytochromes c; Down-Regulation; Drug Evaluation, Preclinical; Drug Screening Assays, Antitumor; Female; Humans; Membrane Potential, Mitochondrial; Mitochondria; Poly(ADP-ribose) Polymerases; Receptors, Death Domain; Signal Transduction; Triterpenes; Up-Regulation; Ursolic Acid

2011
Oldenlandia diffusa extracts exert antiproliferative and apoptotic effects on human breast cancer cells through ERα/Sp1-mediated p53 activation.
    Journal of cellular physiology, 2012, Volume: 227, Issue:10

    Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Drug Resistance, Neoplasm; Estrogen Receptor alpha; Estrogen Receptor Modulators; Estrogens; Female; Gene Expression Regulation, Neoplastic; Humans; Immunoglobulins; Oldenlandia; Oleanolic Acid; Plant Extracts; Promoter Regions, Genetic; Tamoxifen; Transcriptional Activation; Triterpenes; Tumor Suppressor Protein p53; Up-Regulation; Ursolic Acid

2012
In vitro anti-breast cancer activity of ethanolic extract of Wrightia tomentosa: role of pro-apoptotic effects of oleanolic acid and urosolic acid.
    Journal of ethnopharmacology, 2012, Jun-26, Volume: 142, Issue:1

    Topics: Antineoplastic Agents; Apocynaceae; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Ethanol; HEK293 Cells; Humans; L-Lactate Dehydrogenase; Oleanolic Acid; Plant Extracts; Plant Leaves; Solvents; Triterpenes; Ursolic Acid

2012
In vitro and in vivo antimammary tumor activities and mechanisms of the apple total triterpenoids.
    Journal of agricultural and food chemistry, 2012, Sep-19, Volume: 60, Issue:37

    Topics: Animals; Apoptosis; Breast Neoplasms; Caco-2 Cells; Cell Cycle; Cell Proliferation; Female; Fruit; Hep G2 Cells; Humans; Malus; Mammary Neoplasms, Animal; MCF-7 Cells; NF-kappa B; Oleanolic Acid; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Triterpenes; Ursolic Acid

2012
Autophagy-dependent EIF2AK3 activation compromises ursolic acid-induced apoptosis through upregulation of MCL1 in MCF-7 human breast cancer cells.
    Autophagy, 2013, Feb-01, Volume: 9, Issue:2

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Autophagy-Related Protein 5; Beclin-1; Breast Neoplasms; Cell Survival; Cytoprotection; eIF-2 Kinase; Endoplasmic Reticulum Stress; Enzyme Activation; Female; Humans; MCF-7 Cells; Membrane Proteins; Microtubule-Associated Proteins; Mitogen-Activated Protein Kinases; Models, Biological; Myeloid Cell Leukemia Sequence 1 Protein; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; TOR Serine-Threonine Kinases; Triterpenes; Unfolded Protein Response; Up-Regulation; Ursolic Acid; Vacuoles

2013
[Experimental study on MCF-7 cell apoptosis induced by ursolic acid].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2005, Volume: 28, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Humans; Plants, Medicinal; Triterpenes; Tumor Suppressor Protein p53; Ursolic Acid

2005
Cytotoxic activity and effect on nitric oxide production of tirucallane-type triterpenes.
    The Journal of pharmacy and pharmacology, 2005, Volume: 57, Issue:9

    Topics: Anacardiaceae; Animals; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Cell Death; Cell Line, Tumor; Central Nervous System Neoplasms; Colonic Neoplasms; Drug Screening Assays, Antitumor; Female; Hexanes; Humans; Leukemia; Lipopolysaccharides; Macrophages, Peritoneal; Male; Medicine, Traditional; Mexico; Mice; Nitric Oxide; Plant Extracts; Prostatic Neoplasms; Rhodamines; Triterpenes; Ursolic Acid

2005
[Effect of ursolic acid on caspase-3 and PARP expression of human MCF-7 cells].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2006, Volume: 31, Issue:2

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Caspase 3; Caspases; Cell Cycle; Cell Line, Tumor; Female; Humans; Poly(ADP-ribose) Polymerases; Triterpenes; Ursolic Acid

2006
Cranberry phytochemicals: Isolation, structure elucidation, and their antiproliferative and antioxidant activities.
    Journal of agricultural and food chemistry, 2006, Sep-20, Volume: 54, Issue:19

    Topics: Antineoplastic Agents; Antioxidants; Breast Neoplasms; Cell Division; Cell Line, Tumor; Flavonoids; Fruit; Humans; Liver Neoplasms; Phenols; Quercetin; Triterpenes; Ursolic Acid; Vaccinium macrocarpon

2006