Page last updated: 2024-08-24

ursolic acid and Alloxan Diabetes

ursolic acid has been researched along with Alloxan Diabetes in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (12.00)29.6817
2010's18 (72.00)24.3611
2020's4 (16.00)2.80

Authors

AuthorsStudies
Camici, G; Estrada-Soto, S; López-Martínez, S; López-Vallejo, F; Medina-Franco, JL; Navarrete-Vázquez, G; Ortiz-Andrade, R; Paoli, P; Ramírez-Espinosa, JJ; Rios, MY1
Abid, A; Al Mamun, A; Azom, S; Billah, H; Biswas, B; Kerr, PG; Mazumder, K; Saha, B; Sarkar, KK1
Fang, C; Liu, Y; Tang, L; Tang, S; Xu, Y1
Faramarzi, M; Ghaffari, M; Hedayati, M; Zolfaghari, M1
Choi, JH; Choi, S; Choi, YJ; Chung, HY; Hyun, MK; Kim, DH; Lee, JY; Noh, SG; Park, CH; Park, D1
Cheng, JT; Cheng, KC; Li, Y; Lo, SH; Niu, CS; Niu, HS1
Cheng, Y; Gong, Y; Qi, MY; Wang, XT; Yang, JJ; Zhao, JG; Zhou, B1
Camici, G; Cerón-Romero, L; Estrada-Soto, S; Flores-Morales, V; Guzmán-Ávila, R; Hidalgo-Figueroa, S; Navarrete-Vázquez, G; Paoli, P; Ramírez-Espinosa, JJ; Villalobos-Molina, R; Yolanda Rios, M1
Chen, SS; Qi, MY; Wang, XT1
Cheng, Y; Qi, MY; Wang, XT; Xu, HL; Yang, JJ; Zhao, JG; Zhou, YJ1
Gong, Y; Qi, MY; Shi, J; Yang, JJ1
Cho, HW; Kim, MJ; Lee, HI; Lee, J; Lee, MK; Park, EM; Seo, KI1
He, P; Huang, T; Lu, Y; Wu, P; Zhang, K; Zhao, S1
Pan, DY; Qi, MY; Sun, X; Yang, JJ; Zhou, B1
Sun, JH; Xu, XE; Yu, PF; Yu, SG; Zhang, CJ; Zhang, L1
Feng, M; He, K; Li, X; Song, S; Wang, D; Wang, Y; Ye, X; Zou, Z1
Choi, J; Choi, MS; Do, GM; Jang, SM; Jeon, SM; Kim, MJ; Lee, MK; Seo, KI; Yee, ST; Yeo, J1
Gallardo Navarro, Y; Garcia Baez, E; Pérez Gutiérrez, RM; Vargas Solis, R1
Choi, MS; Jang, SM; Kim, MJ; Kwon, EY; Lee, MK1
Choi, MS; Kim, JJ; Kwon, EY; Lee, J; Lee, MK; Seo, KI; Yee, ST1
Asmis, R; Ullevig, SL; Zamora, D; Zhao, Q1
Tannock, LR1
Afzal, M; Afzal, O; Ahmed, S; Anwar, F; Gupta, G; Kazmi, I; Nautiyal, U; Rahman, M; Saleem, S; Shaharyar, MA1
Ling, J; Wang, J; Xiang, M; Xu, X; Zhang, Y1
Chen, CC; Chen, CY; Hsu, CY; Liu, HK1

Other Studies

25 other study(ies) available for ursolic acid and Alloxan Diabetes

ArticleYear
Antidiabetic activity of some pentacyclic acid triterpenoids, role of PTP-1B: in vitro, in silico, and in vivo approaches.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:6

    Topics: Animals; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Enzyme Activation; Enzyme Inhibitors; Humans; Hypoglycemic Agents; Male; Models, Molecular; Molecular Conformation; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Rats; Rats, Wistar; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship; Triterpenes

2011
Investigations of AGEs' inhibitory and nephroprotective potential of ursolic acid towards reduction of diabetic complications.
    Journal of natural medicines, 2022, Volume: 76, Issue:2

    Topics: Animals; Diabetes Complications; Diabetes Mellitus, Experimental; Glycation End Products, Advanced; Mice; Receptor for Advanced Glycation End Products; Triterpenes; Ursolic Acid

2022
Anti-obesity and Anti-diabetic Effect of Ursolic Acid against Streptozotocin/High Fat Induced Obese in Diabetic Rats.
    Journal of oleo science, 2022, Feb-03, Volume: 71, Issue:2

    Topics: Administration, Oral; Animals; Anti-Obesity Agents; Antioxidants; Diabetes Mellitus, Experimental; Diet, High-Fat; Dose-Response Relationship, Drug; Glucose; Hypoglycemic Agents; Insulin; Lipid Metabolism; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Obesity; Oxidative Stress; Rats, Wistar; Streptozocin; Triterpenes; Ursolic Acid

2022
The effect of resistance and endurance training with ursolic acid on atrophy-related biomarkers in muscle tissue of diabetic male rats induced by streptozotocin and a high-fat diet.
    Journal of food biochemistry, 2022, Volume: 46, Issue:8

    Topics: Animals; Atrophy; Biomarkers; Diabetes Mellitus, Experimental; Diet, High-Fat; Endurance Training; Humans; Male; Muscle, Skeletal; Rats; Rats, Wistar; Streptozocin; Triterpenes; Tumor Suppressor Protein p53; Ursolic Acid

2022
Protective mechanisms of loquat leaf extract and ursolic acid against diabetic pro-inflammation.
    Journal of molecular medicine (Berlin, Germany), 2022, Volume: 100, Issue:10

    Topics: AMP-Activated Protein Kinases; Animals; Antioxidants; Diabetes Mellitus, Experimental; Eriobotrya; Hyperglycemia; Inflammation; Mice; Oleanolic Acid; Plant Extracts; Ursolic Acid

2022
Ursolic acid activates the TGR5 receptor to enhance GLP-1 secretion in type 1-like diabetic rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 2017, Volume: 390, Issue:11

    Topics: Animals; Blood Glucose; Cell Line; CHO Cells; Cricetulus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Glucagon-Like Peptide 1; Humans; Male; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Triterpenes; Ursolic Acid

2017
Ursolic acid ameliorates oxidative stress, inflammation and fibrosis in diabetic cardiomyopathy rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 97

    Topics: Animals; Chemokine CCL2; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Down-Regulation; Fibrosis; Gene Expression Regulation; Inflammation; Male; Matrix Metalloproteinase 2; Oxidative Stress; Rats; Rats, Sprague-Dawley; Streptozocin; Transforming Growth Factor beta1; Triterpenes; Tumor Necrosis Factor-alpha; Up-Regulation; Ursolic Acid

2018
Ursolic acid derivatives as potential antidiabetic agents: In vitro, in vivo, and in silico studies.
    Drug development research, 2018, Volume: 79, Issue:2

    Topics: Animals; Blood Glucose; Computer Simulation; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Male; Mice; Molecular Conformation; Molecular Docking Simulation; Molecular Structure; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Recombinant Fusion Proteins; Triterpenes; Ursolic Acid

2018
[Effects of ursolic acid on liver injury and its possible mechanism in diabetes mellitus mice].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2018, Feb-08, Volume: 34, Issue:2

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Diet, High-Fat; Fatty Liver; Liver; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Random Allocation; Superoxide Dismutase; Triglycerides; Triterpenes; Ursolic Acid

2018
Ursolic acid improves diabetic nephropathy via suppression of oxidative stress and inflammation in streptozotocin-induced rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 105

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Inflammation; Inflammation Mediators; Kidney; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Streptozocin; Triterpenes; Ursolic Acid

2018
[Study on the effect of ursolic acid (UA) on the myocardial fibrosis of experimental diabetic mice].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2013, Volume: 29, Issue:4

    Topics: Animals; Blood Glucose; Collagen; Diabetes Mellitus, Experimental; Fibrosis; Hydroxyproline; Male; Malondialdehyde; Mice; Mice, Inbred Strains; Myocardium; Oxidative Stress; Superoxide Dismutase; Transforming Growth Factor beta1; Triterpenes; Ursolic Acid

2013
Effects of ursolic acid on glucose metabolism, the polyol pathway and dyslipidemia in non-obese type 2 diabetic mice.
    Indian journal of experimental biology, 2014, Volume: 52, Issue:7

    Topics: Animals; Antineoplastic Agents, Phytogenic; Blotting, Western; Diabetes Complications; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dyslipidemias; Glucokinase; Glucose; Glucose Transporter Type 2; Glucose-6-Phosphatase; Glycogen; Hyperglycemia; Kidney Diseases; Male; Mice; Mice, Inbred ICR; Mice, Inbred NOD; Polymers; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Triterpenes; Ursolic Acid

2014
Effects of ursolic acid derivatives on Caco-2 cells and their alleviating role in streptozocin-induced type 2 diabetic rats.
    Molecules (Basel, Switzerland), 2014, Aug-19, Volume: 19, Issue:8

    Topics: Animals; Blood Glucose; Caco-2 Cells; Carbohydrate Metabolism; Diabetes Mellitus, Experimental; Drug Evaluation, Preclinical; Glucose; Glucose Transporter Type 2; Humans; Hypoglycemic Agents; Male; Oxidative Stress; Rats, Sprague-Dawley; Sodium-Glucose Transporter 1; Streptozocin; Triterpenes; Ursolic Acid

2014
[Study on the protective effect of ursolic acid on alloxan-induced diabetic renal injury and its underlying mechanisms].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2014, Volume: 30, Issue:5

    Topics: Alloxan; Animals; Antioxidants; Blood Glucose; Blood Urea Nitrogen; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Interleukin-6; Kidney; Male; Mice; Superoxide Dismutase; Triterpenes; Tumor Necrosis Factor-alpha; Ursolic Acid

2014
Ursolic acid derivative ameliorates streptozotocin-induced diabestic bone deleterious effects in mice.
    International journal of clinical and experimental pathology, 2015, Volume: 8, Issue:4

    Topics: Animals; Bone Density; Calcium; Diabetes Mellitus, Experimental; Femur; Fibroblast Growth Factor-23; Insulin; Insulin-Like Growth Factor I; Male; Mice; Mice, Inbred C57BL; Osteoprotegerin; RANK Ligand; Tibia; Triterpenes; Ursolic Acid

2015
The Hypoglycemic and Synergistic Effect of Loganin, Morroniside, and Ursolic Acid Isolated from the Fruits of Cornus officinalis.
    Phytotherapy research : PTR, 2016, Volume: 30, Issue:2

    Topics: alpha-Glucosidases; Animals; China; Cornus; Diabetes Mellitus, Experimental; Free Radical Scavengers; Fruit; Glycosides; Hep G2 Cells; Humans; Hypoglycemic Agents; Iridoids; Male; Mice; Plant Extracts; Plants, Medicinal; Reactive Oxygen Species; Triterpenes; Ursolic Acid

2016
Ursolic acid enhances the cellular immune system and pancreatic beta-cell function in streptozotocin-induced diabetic mice fed a high-fat diet.
    International immunopharmacology, 2009, Volume: 9, Issue:1

    Topics: Adjuvants, Immunologic; Animals; Antigens, Surface; Blood Glucose; C-Peptide; Cytokines; Diabetes Mellitus, Experimental; Diet; Dietary Fats; Dietary Supplements; Glucose Tolerance Test; Hyperglycemia; Hypoglycemic Agents; Immunity, Cellular; Immunohistochemistry; Insulin; Insulin-Secreting Cells; Lymphocytes; Male; Mice; Mice, Inbred ICR; Pancreas; Pancreatic Function Tests; Triterpenes; Ursolic Acid

2009
Hypoglycemic activity of constituents from Astianthus viminalis in normal and streptozotocin-induced diabetic mice.
    Journal of natural medicines, 2009, Volume: 63, Issue:4

    Topics: Animals; Blood Glucose; Coumarins; Diabetes Mellitus, Experimental; Female; Hypoglycemic Agents; Magnetic Resonance Spectroscopy; Male; Mice; Plant Extracts; Plants, Medicinal; Triterpenes; Ursolic Acid

2009
Inhibitory effects of ursolic acid on hepatic polyol pathway and glucose production in streptozotocin-induced diabetic mice.
    Metabolism: clinical and experimental, 2010, Volume: 59, Issue:4

    Topics: Aldehyde Reductase; Animals; Diabetes Mellitus, Experimental; Glucokinase; Glucose; Leptin; Liver; Male; Mice; Mice, Inbred ICR; Polymers; Streptozocin; Succinate Dehydrogenase; Triterpenes; Ursolic Acid

2010
Ursolic acid ameliorates thymic atrophy and hyperglycemia in streptozotocin-nicotinamide-induced diabetic mice.
    Chemico-biological interactions, 2010, Dec-05, Volume: 188, Issue:3

    Topics: Animals; Atrophy; Blood Glucose; Body Weight; Cell Proliferation; Cytokines; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Glucose Tolerance Test; Glycated Hemoglobin; Hyperglycemia; Insulin; Leptin; Lymphocytes; Male; Mice; Mice, Inbred ICR; Niacinamide; Pancreas; Spleen; Thymus Gland; Transaminases; Triterpenes; Ursolic Acid

2010
Ursolic acid protects diabetic mice against monocyte dysfunction and accelerated atherosclerosis.
    Atherosclerosis, 2011, Volume: 219, Issue:2

    Topics: Animals; Aortic Diseases; Atherosclerosis; Cardiovascular Agents; Cell Line; Chemokine CCL2; Chemotaxis, Leukocyte; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Dose-Response Relationship, Drug; Female; Humans; Hyperlipidemias; Kidney; Macrophages; Mice; Mice, Inbred C57BL; Mice, Knockout; Monocytes; Oxidative Stress; Receptors, CCR2; Receptors, LDL; Resveratrol; Stilbenes; Time Factors; Triterpenes; Ursolic Acid

2011
Ursolic acid effect on atherosclerosis: apples and apples, or apples and oranges?
    Atherosclerosis, 2011, Volume: 219, Issue:2

    Topics: Animals; Aortic Diseases; Apoptosis; Atherosclerosis; Cardiovascular Agents; Caspases; Diabetes Mellitus, Experimental; Diabetic Angiopathies; DNA Damage; Female; Human Umbilical Vein Endothelial Cells; Humans; Male; Mitochondria; Monocytes; Plaque, Atherosclerotic; Triterpenes; Tumor Suppressor Protein p53; Ursolic Acid

2011
Anti-diabetic potential of ursolic acid stearoyl glucoside: a new triterpenic gycosidic ester from Lantana camara.
    Fitoterapia, 2012, Volume: 83, Issue:1

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glucosides; Hypoglycemic Agents; Lantana; Molecular Structure; Plant Leaves; Rats; Sterols; Triterpenes; Ursolic Acid

2012
Attenuation of aortic injury by ursolic acid through RAGE-Nox-NFκB pathway in streptozocin-induced diabetic rats.
    Archives of pharmacal research, 2012, Volume: 35, Issue:5

    Topics: Animals; Aorta, Thoracic; Diabetes Mellitus, Experimental; Male; NADPH Oxidases; NF-kappa B; Random Allocation; Rats; Rats, Sprague-Dawley; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Signal Transduction; Triterpenes; Ursolic Acid

2012
Fructus Corni suppresses hepatic gluconeogenesis related gene transcription, enhances glucose responsiveness of pancreatic beta-cells, and prevents toxin induced beta-cell death.
    Journal of ethnopharmacology, 2008, May-22, Volume: 117, Issue:3

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Blotting, Western; Cell Death; Cell Survival; Cells, Cultured; Cornus; Dexamethasone; Diabetes Mellitus, Experimental; Electrophoresis, Polyacrylamide Gel; Fruit; Gene Expression; Gluconeogenesis; Glucose; Humans; Insulin; Insulin-Secreting Cells; Iridoids; Liver; Phosphoenolpyruvate Carboxykinase (ATP); Rats; RNA, Messenger; Triterpenes; Ursolic Acid

2008