Page last updated: 2024-08-24

ursolic acid and Acute Liver Injury, Drug-Induced

ursolic acid has been researched along with Acute Liver Injury, Drug-Induced in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (33.33)29.6817
2010's4 (44.44)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Biswas, S; Haldar, PK; Kar, A; Mukherjee, PK; Sharma, N1
Bai, G; Chu, S; Jiang, M; Liu, W; Lu, Y; Ma, X; Peng, J; Wang, X1
Bannerjee, S; Bhattacharjee, P; Biswas, S; Harwansh, RK; Mukherjee, PK1
Ding, J; Liu, CM; Ma, JQ; Zhang, L1
Dai, Z; Teng, Y; Wu, B; Xu, Y; Zhong, Y1
Hao, XS; Qian, ZZ; Qiu, LH; Song, Z; Wang, HQ; Wang, P; Wang, XH; Zhang, HL; Zhao, J; Zhou, SY1
Chen, W; Cui, J; Li, K; Xiong, X; Yi, S; Zhang, Z1
Ahmed, M; Krishna, V; Manjunatha, BK; Mankani, KL; Singh, SD; Vidya, SM1
Benedi, J; de las Heras, B; Martin-Aragón, S; Sanchez-Reus, MI1

Trials

1 trial(s) available for ursolic acid and Acute Liver Injury, Drug-Induced

ArticleYear
Evaluation of toxicity and single-dose pharmacokinetics of intravenous ursolic acid liposomes in healthy adult volunteers and patients with advanced solid tumors.
    Expert opinion on drug metabolism & toxicology, 2013, Volume: 9, Issue:2

    Topics: Adult; Antineoplastic Agents, Phytogenic; Chemical and Drug Induced Liver Injury; Cohort Studies; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Gastrointestinal Diseases; Humans; Infusions, Intravenous; Liposomes; Male; Middle Aged; Neoplasms; Triterpenes; Ursolic Acid; Young Adult

2013

Other Studies

8 other study(ies) available for ursolic acid and Acute Liver Injury, Drug-Induced

ArticleYear
Synergistic effect of ursolic acid and piperine in CCl
    Annals of medicine, 2021, Volume: 53, Issue:1

    Topics: Alkaloids; Animals; Benzodioxoles; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Humans; Liver; Piperidines; Polyunsaturated Alkamides; Protective Agents; Rats; Triterpenes; Ursolic Acid

2021
Ursolic acid alleviates tetrandrine-induced hepatotoxicity by competitively binding to the substrate-binding site of glutathione S-transferases.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2022, Volume: 104

    Topics: Antineoplastic Agents; Benzylisoquinolines; Binding Sites; Chemical and Drug Induced Liver Injury; Glutathione; Glutathione Transferase; Humans; Transferases; Triterpenes; Ursolic Acid

2022
Enhanced bioavailability and hepatoprotectivity of optimized ursolic acid-phospholipid complex.
    Drug development and industrial pharmacy, 2019, Volume: 45, Issue:6

    Topics: Administration, Oral; Animals; Biological Availability; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Computer Simulation; Disease Models, Animal; Drug Compounding; Drug Liberation; Excipients; Half-Life; Humans; Liver; Male; Molecular Docking Simulation; Molecular Structure; Particle Size; Phospholipids; Protective Agents; Rats; Rats, Wistar; Solubility; Triterpenes; Ursolic Acid; X-Ray Diffraction

2019
Ursolic acid protects mouse liver against CCl4-induced oxidative stress and inflammation by the MAPK/NF-κB pathway.
    Environmental toxicology and pharmacology, 2014, Volume: 37, Issue:3

    Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Antioxidants; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cyclooxygenase 2; Interleukin-6; Liver; Male; Mice, Inbred ICR; Mitogen-Activated Protein Kinases; NF-kappa B; Oxidative Stress; Reactive Oxygen Species; Signal Transduction; Thiobarbituric Acid Reactive Substances; Triterpenes; Tumor Necrosis Factor-alpha; Ursolic Acid

2014
Synthesis, stability and pharmacological evaluation of a novel codrug consisting of lamivudine and ursolic acid.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2012, Jan-23, Volume: 45, Issue:1-2

    Topics: Animals; Antiviral Agents; Chemical and Drug Induced Liver Injury; Drug Combinations; Drug Stability; Ducks; Half-Life; Hepadnaviridae Infections; Hepatitis B Virus, Duck; Hepatitis, Viral, Animal; Humans; Hydrogen-Ion Concentration; Hydrolysis; Lamivudine; Lipase; Mice; Mice, Inbred ICR; Plasma; Prodrugs; Protective Agents; Random Allocation; Triterpenes; Ursolic Acid

2012
[Effects of ursolic acid on liver-protection and bile secretion].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2003, Volume: 26, Issue:8

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bile; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Drugs, Chinese Herbal; Female; Isothiocyanates; Liver; Male; Mice; Plants, Medicinal; Protective Agents; Random Allocation; Rats; Rats, Wistar; Sambucus; Triterpenes; Ursolic Acid

2003
Evaluation of hepatoprotective activity of Clerodendrum serratum L.
    Indian journal of experimental biology, 2007, Volume: 45, Issue:6

    Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Clerodendrum; Cytoprotection; Liver; Liver Diseases; Male; Models, Biological; Phytotherapy; Plant Extracts; Protective Agents; Rats; Rats, Wistar; Triterpenes; Ursolic Acid

2007
Pharmacological modification of endogenous antioxidant enzymes by ursolic acid on tetrachloride-induced liver damage in rats and primary cultures of rat hepatocytes.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2001, Volume: 53, Issue:2-3

    Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Carbon Tetrachloride; Catalase; Cell Survival; Cells, Cultured; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Hepatocytes; Hydroxyl Radical; Lipid Peroxidation; Liver; Random Allocation; Rats; Superoxide Dismutase; Triterpenes; Ursolic Acid

2001