ursodeoxycholic acid has been researched along with Necrosis in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (31.58) | 18.2507 |
| 2000's | 9 (47.37) | 29.6817 |
| 2010's | 2 (10.53) | 24.3611 |
| 2020's | 2 (10.53) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, Y; Duan, Y; Han, J; Liu, L; Yang, S; Yang, X; Zhang, S | 1 |
| Behar-Cohen, F; Berdugo, M; Bertrand, M; Boatright, J; Daruich, A; Delaunay, K; Henry, H; Jaworski, T; Kowalczuk, L; Naud, MC; Parenti, L; Picard, E; Youale, J; Zola, M | 1 |
| Choi, JE; Han, SI; Kang, HS; Lim, SC; Si, H | 1 |
| Choi, JE; Duong, HQ; Han, SI; Kang, JH; Lee, TB; Lim, SC; Oh, SH | 1 |
| Denk, H; Fickert, P; Fuchsbichler, A; Lammert, F; Marschall, HU; Stumptner, C; Trauner, M; Tsybrovskyy, O; Weiglein, AH; Zatloukal, K; Zollner, G | 1 |
| Forget, PP; Heemskerk, J; Heineman, E; Sie, GH; Van den Neucker, AM; van Heurn, LW | 1 |
| Ribal'chenko, VK; Sinel'nik, OD; Sinel'nik, TB | 1 |
| Holy, JM; Palmeira, CM; Rolo, AP; Wallace, KB | 1 |
| Angulo, P; Burgart, L; Colin, P; Harrison, ME; Heathcote, EJ; Jorgensen, R; Kowdley, KV; Lindor, KD; Lymp, JF | 1 |
| Chrétien, Y; Corpechot, C; Galotte, M; Poujol-Robert, A; Poupon, R; Poupon, RE; Wendum, D | 1 |
| Ballestero, MR; Briz, O; Marin, JJ; Monte, MJ; Perez, MJ | 1 |
| Attia, M; Badran, HM; Barakat, E; El-Nakeeb, A; El-Tawil, A; El-Zayadi, AR; Saied, A; Selim, O; Zalata, K | 1 |
| Batta, AK; Chen, T; Kren, BT; Nguyen, LB; Salen, G; Shefer, S; Steer, CJ; Tint, GS | 1 |
| Antezana, C; Brahm, J; Cumsille, MA; González-Koch, A; Smok, G | 1 |
| Aguilar, HI; Botla, R; Bronk, SF; Gores, GJ; Miyoshi, H | 1 |
| Angulo, P; Batts, KP; Larson, DR; LaRusso, NF; Lindor, KD; Therneau, TM | 1 |
| Carrat, F; Corpechot, C; Poupon, R; Poupon, RE | 1 |
| Heuman, DM; Hylemon, PB; Pandak, WM; Vlahcevic, ZR | 1 |
| Heuman, DM; Hylemon, PB; McCall, J; Mills, AS; Pandak, WM; Vlahcevic, ZR | 1 |
1 review(s) available for ursodeoxycholic acid and Necrosis
| Article | Year |
|---|---|
[Bile acids in the process of canalicular bile formation].
Topics: Animals; Apoptosis; Bile; Bile Acids and Salts; Bile Canaliculi; Biological Transport, Active; Cholestasis; Gene Expression Regulation; Hepatocytes; Humans; Hydrophobic and Hydrophilic Interactions; Membrane Transport Proteins; Necrosis; Ursodeoxycholic Acid | 2003 |
3 trial(s) available for ursodeoxycholic acid and Necrosis
| Article | Year |
|---|---|
Ursodeoxycholic acid for treatment of nonalcoholic steatohepatitis: results of a randomized trial.
Topics: Alanine Transaminase; Aspartate Aminotransferases; Cholagogues and Choleretics; Disease Progression; Double-Blind Method; Fatty Liver; Fibrosis; Humans; Liver; Necrosis; Ursodeoxycholic Acid | 2004 |
Non-interferon-based therapy: an option for amelioration of necro-inflammation in hepatitis C patients who cannot afford interferon therapy.
Topics: Alanine Transaminase; Amantadine; Antiviral Agents; Drug Therapy, Combination; Female; Hepacivirus; Hepatitis C, Chronic; Humans; Interferons; Liver; Male; Middle Aged; Necrosis; Protective Agents; Ribavirin; RNA, Viral; Silymarin; Treatment Outcome; Ursodeoxycholic Acid | 2005 |
The combination of ursodeoxycholic acid and methotrexate for primary biliary cirrhosis is not better than ursodeoxycholic acid alone.
Topics: Adult; Aged; Cholagogues and Choleretics; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Liver; Liver Cirrhosis, Biliary; Methotrexate; Middle Aged; Necrosis; Prospective Studies; Treatment Outcome; Ursodeoxycholic Acid | 1997 |
15 other study(ies) available for ursodeoxycholic acid and Necrosis
| Article | Year |
|---|---|
A novel therapy for hepatic cholestasis treatment-the combination of rosiglitazone and fenofibrate.
Topics: Animals; Cholestasis; Fenofibrate; Liver; Mice; Mice, Inbred C57BL; Necrosis; Rosiglitazone; Ursodeoxycholic Acid | 2023 |
Oral Ursodeoxycholic Acid Crosses the Blood Retinal Barrier in Patients with Retinal Detachment and Protects Against Retinal Degeneration in an Ex Vivo Model.
Topics: Administration, Oral; Albumins; Animals; Apoptosis; Biological Availability; Blood-Retinal Barrier; Cell Line; Cholagogues and Choleretics; Cryosurgery; Female; Humans; In Vitro Techniques; Laser Therapy; Male; Middle Aged; Necrosis; Photoreceptor Cells, Vertebrate; Rats; Retina; Retinal Cone Photoreceptor Cells; Retinal Degeneration; Retinal Detachment; Subretinal Fluid; Ursodeoxycholic Acid; Vitrectomy | 2021 |
Ursodeoxycholic acid switches oxaliplatin-induced necrosis to apoptosis by inhibiting reactive oxygen species production and activating p53-caspase 8 pathway in HepG2 hepatocellular carcinoma.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Caspase 8; Cholagogues and Choleretics; Electrophoretic Mobility Shift Assay; Hep G2 Cells; HT29 Cells; Humans; L-Lactate Dehydrogenase; Liver Neoplasms; Necrosis; Organoplatinum Compounds; Oxaliplatin; Reactive Oxygen Species; RNA, Small Interfering; Tumor Suppressor Protein p53; Ursodeoxycholic Acid | 2010 |
Lipid raft-dependent death receptor 5 (DR5) expression and activation are critical for ursodeoxycholic acid-induced apoptosis in gastric cancer cells.
Topics: Animals; Apoptosis; Blotting, Western; Cell Proliferation; Cholagogues and Choleretics; Humans; Membrane Microdomains; Mice; Mice, Inbred BALB C; Necrosis; Protein Kinase C-delta; Reactive Oxygen Species; Receptors, TNF-Related Apoptosis-Inducing Ligand; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Stomach Neoplasms; Tumor Cells, Cultured; Ursodeoxycholic Acid | 2011 |
Ursodeoxycholic acid aggravates bile infarcts in bile duct-ligated and Mdr2 knockout mice via disruption of cholangioles.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Bile; Bile Acids and Salts; Cholagogues and Choleretics; Cholangitis, Sclerosing; Cholestasis, Extrahepatic; Common Bile Duct; Disease Models, Animal; Infarction; Ligation; Male; Mice; Mice, Knockout; Necrosis; Pressure; Ursodeoxycholic Acid | 2002 |
Extreme short bowel syndrome in a full-term neonate--a case report.
Topics: Anastomosis, Surgical; Breast Feeding; Cholagogues and Choleretics; Cholestasis; Diarrhea, Infantile; Humans; Infant, Newborn; Intestinal Volvulus; Intestines; Liver Function Tests; Male; Necrosis; Parenteral Nutrition; Short Bowel Syndrome; Steatorrhea; Ursodeoxycholic Acid | 2003 |
Role of mitochondrial dysfunction in combined bile acid-induced cytotoxicity: the switch between apoptosis and necrosis.
Topics: Adenosine Triphosphate; Apoptosis; Bile Acids and Salts; Bromodeoxyuridine; Caspase 9; Caspases; Cell Cycle; Cell Division; Cell Line; Cell Membrane Permeability; Cell Survival; Chenodeoxycholic Acid; Chromatin; Cytochromes c; DNA; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Synergism; Humans; Mitochondrial Diseases; Necrosis; Poly(ADP-ribose) Polymerases; Taurochenodeoxycholic Acid; Time Factors; Tubulin; Ursodeoxycholic Acid | 2004 |
Biochemical markers of liver fibrosis and lymphocytic piecemeal necrosis in UDCA-treated patients with primary biliary cirrhosis.
Topics: Aspartate Aminotransferases; Bile Ducts, Intrahepatic; Bilirubin; Biomarkers; Cholagogues and Choleretics; Female; Humans; Hyaluronic Acid; Liver; Liver Cirrhosis; Liver Cirrhosis, Biliary; Lymphocytes; Male; Middle Aged; Necrosis; Predictive Value of Tests; Sensitivity and Specificity; Ursodeoxycholic Acid | 2004 |
Proapoptotic effect on normal and tumor intestinal cells of cytostatic drugs with enterohepatic organotropism.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; DNA Adducts; DNA Fragmentation; Humans; Intestinal Neoplasms; Intestine, Small; Male; Mice; Necrosis; Organoplatinum Compounds; Ursodeoxycholic Acid | 2005 |
Regulation of bile acid synthesis by deoxycholic acid in the rat: different effects on cholesterol 7 alpha-hydroxylase and sterol 27-hydroxylase.
Topics: Animals; Bile; Bile Acids and Salts; Cell Nucleus; Chemical and Drug Induced Liver Injury; Cholagogues and Choleretics; Cholestanetriol 26-Monooxygenase; Cholesterol 7-alpha-Hydroxylase; Cytochrome P-450 Enzyme System; Deoxycholic Acid; Diet; Hydroxymethylglutaryl CoA Reductases; Liver; Liver Diseases; Male; Necrosis; Rats; Rats, Sprague-Dawley; RNA, Messenger; Steroid Hydroxylases; Ursodeoxycholic Acid | 1995 |
Induction of the mitochondrial permeability transition as a mechanism of liver injury during cholestasis: a potential role for mitochondrial proteases.
Topics: Animals; ATP-Dependent Proteases; Calcium Channels; Calpain; Cholestasis; Enzyme Activation; Glycochenodeoxycholic Acid; Liver; Mitochondria, Liver; Necrosis; Permeability; Serine Endopeptidases; Ursodeoxycholic Acid | 1998 |
Time course of histological progression in primary sclerosing cholangitis.
Topics: Adolescent; Adult; Aged; Biopsy; Cholagogues and Choleretics; Cholangitis, Sclerosing; Disease Progression; Female; Follow-Up Studies; Hepatitis; Humans; Liver; Liver Cirrhosis; Liver Cirrhosis, Biliary; Male; Markov Chains; Middle Aged; Necrosis; Penicillamine; Time Factors; Treatment Outcome; Ursodeoxycholic Acid | 1999 |
Primary biliary cirrhosis: incidence and predictive factors of cirrhosis development in ursodiol-treated patients.
Topics: Bilirubin; Cholagogues and Choleretics; Disease Progression; Female; Humans; Incidence; Liver; Liver Cirrhosis, Biliary; Male; Markov Chains; Middle Aged; Multivariate Analysis; Necrosis; Predictive Value of Tests; Prognosis; Risk Factors; Serum Albumin; Ursodeoxycholic Acid | 2002 |
Conjugates of ursodeoxycholate protect against cytotoxicity of more hydrophobic bile salts: in vitro studies in rat hepatocytes and human erythrocytes.
Topics: Animals; Bile Acids and Salts; Cell Survival; Cells, Cultured; Erythrocytes; Humans; Liver; Necrosis; Rats; Ursodeoxycholic Acid | 1991 |
Conjugates of ursodeoxycholate protect against cholestasis and hepatocellular necrosis caused by more hydrophobic bile salts. In vivo studies in the rat.
Topics: Animals; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Cholestasis; Liver Diseases; Male; Necrosis; Rats; Rats, Inbred Strains; Ursodeoxycholic Acid | 1991 |