Page last updated: 2024-08-23

ursodeoxycholic acid and Idiopathic Parkinson Disease

ursodeoxycholic acid has been researched along with Idiopathic Parkinson Disease in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (40.00)24.3611
2020's6 (60.00)2.80

Authors

AuthorsStudies
Aasly, J; Bandmann, O; Cameron, SA; Clemmens, H; Furneaux, RH; Harris, LD; Hastings, C; Luxenburger, A; Mortiboys, H; Ure, EM; Weymouth-Wilson, A1
Appleby, M; Bandmann, O; Buckley, E; Dunning, MJ; Foltynie, T; Hernandez, D; Jenkins, TM; Libri, V; Marchesi, JR; Mazzà, C; McNeill, A; Moll, S; Mullish, BH; Payne, T; Sassani, M; Scholz, SW; Su, L; Taylor, R; van Gelder, LMA1
Chen, C; Chen, W; Cloyd, J; Coles, LD; Lee, BY; Low, WC; Ma, Y; Sathe, AG; Steer, CJ; Tuite, P; Zhu, XH1
Bandmann, O; Carling, PJ; Clemmens, H; Evetts, S; Ferraiuolo, L; Green, C; Hastings, C; Hide, W; Hu, MT; Hughes, R; Lo, C; Mihaylov, S; Mortiboys, H; Payne, T; Sandor, C; Schwartzentruber, A; Talbot, K; Taylor, R; Wade-Martins, R; Webber, C; Wei, W; Willcox, S; Wong, S; Wyles, M1
Beggiato, S; Dalpiaz, A; de Oliveira Junior, ER; Ferraro, L; Fogagnolo, M; Leo, E; Lima, EM; Maretti, E; Pavan, B; Rustichelli, C; Truzzi, E1
Anton, A; Appleby, M; Bandmann, O; Buckley, E; Foltynie, T; Hoggard, N; Jenkins, T; Maru, S; Mazza, C; McNeill, A; Moll, S; Payne, T; Sassani, M; Taylor, R; Wilkinson, ID1
Aasly, J; Bandmann, O; Mortiboys, H1
Abdelkader, NF; Safar, MM; Salem, HA1
Gasser, T; Greenamyre, JT; Sanders, LH1
Aasly, J; Bandmann, O; Bronstad, G; Elliott, C; Furmston, R; Mortiboys, H1

Trials

3 trial(s) available for ursodeoxycholic acid and Idiopathic Parkinson Disease

ArticleYear
A Double-Blind, Randomized, Placebo-Controlled Trial of Ursodeoxycholic Acid (UDCA) in Parkinson's Disease.
    Movement disorders : official journal of the Movement Disorder Society, 2023, Volume: 38, Issue:8

    Topics: Double-Blind Method; Humans; Parkinson Disease; Ursodeoxycholic Acid

2023
Pharmacokinetics, Safety, and Tolerability of Orally Administered Ursodeoxycholic Acid in Patients With Parkinson's Disease-A Pilot Study.
    Journal of clinical pharmacology, 2020, Volume: 60, Issue:6

    Topics: Adenosine Triphosphate; Administration, Oral; Aged; Brain; Cognition; Drug Administration Schedule; Female; Gastrointestinal Diseases; Humans; Magnetic Resonance Imaging; Male; Mental Status and Dementia Tests; Middle Aged; Neuroprotective Agents; Parkinson Disease; Pilot Projects; Prospective Studies; Treatment Outcome; Ursodeoxycholic Acid

2020
Ursodeoxycholic acid as a novel disease-modifying treatment for Parkinson's disease: protocol for a two-centre, randomised, double-blind, placebo-controlled trial, The 'UP' study.
    BMJ open, 2020, 08-05, Volume: 10, Issue:8

    Topics: Disease Progression; Double-Blind Method; England; Humans; Parkinson Disease; Randomized Controlled Trials as Topic; Treatment Outcome; Ursodeoxycholic Acid

2020

Other Studies

7 other study(ies) available for ursodeoxycholic acid and Idiopathic Parkinson Disease

ArticleYear
3α,7-Dihydroxy-14(13→12)
    Biomolecules, 2022, 12-30, Volume: 13, Issue:1

    Topics: Bile Acids and Salts; Cholanes; Humans; Parkinson Disease; Ursodeoxycholic Acid

2022
Deep phenotyping of peripheral tissue facilitates mechanistic disease stratification in sporadic Parkinson's disease.
    Progress in neurobiology, 2020, Volume: 187

    Topics: Aged; Cell Differentiation; Cells, Cultured; Female; Fibroblasts; Gene Expression Profiling; Humans; Lysosomes; Male; Middle Aged; Mitochondria; Neurons; Parkinson Disease; Phenotype; Transcriptome; Ursodeoxycholic Acid

2020
Nasal administration of nanoencapsulated geraniol/ursodeoxycholic acid conjugate: Towards a new approach for the management of Parkinson's disease.
    Journal of controlled release : official journal of the Controlled Release Society, 2020, 05-10, Volume: 321

    Topics: Acyclic Monoterpenes; Administration, Intranasal; Animals; Antiparkinson Agents; Parkinson Disease; Rats; Ursodeoxycholic Acid

2020
Ursocholanic acid rescues mitochondrial function in common forms of familial Parkinson's disease.
    Brain : a journal of neurology, 2013, Volume: 136, Issue:Pt 10

    Topics: Adult; Cholic Acids; Humans; Membrane Potential, Mitochondrial; Middle Aged; Mitochondria; Mutation; Neurons; Parkinson Disease; Ursodeoxycholic Acid

2013
Ursodeoxycholic Acid Ameliorates Apoptotic Cascade in the Rotenone Model of Parkinson's Disease: Modulation of Mitochondrial Perturbations.
    Molecular neurobiology, 2016, Volume: 53, Issue:2

    Topics: Adenosine Triphosphate; Animals; Apoptosis; Behavior, Animal; Caspases; Disease Models, Animal; Dopamine; Gene Expression Regulation; Male; Mitochondria; Neostriatum; Neurons; Parkinson Disease; Rats, Wistar; RNA, Messenger; Rotenone; Ursodeoxycholic Acid

2016
Fruit flies, bile acids, and Parkinson disease: a mitochondrial connection?
    Neurology, 2015, Sep-08, Volume: 85, Issue:10

    Topics: Animals; Female; Heterozygote; Humans; Male; Mitochondria; Parkinson Disease; Protein Serine-Threonine Kinases; Ursodeoxycholic Acid

2015
UDCA exerts beneficial effect on mitochondrial dysfunction in LRRK2(G2019S) carriers and in vivo.
    Neurology, 2015, Sep-08, Volume: 85, Issue:10

    Topics: Adult; Aged; Animals; Animals, Genetically Modified; Drosophila; Female; Heterozygote; Humans; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Male; Middle Aged; Mitochondria; Parkinson Disease; Protein Serine-Threonine Kinases; Treatment Outcome; Ursodeoxycholic Acid

2015