Page last updated: 2024-08-23

ursodeoxycholic acid and Esophageal Neoplasms

ursodeoxycholic acid has been researched along with Esophageal Neoplasms in 7 studies

Research

Studies (7)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (14.29)	29.6817
2010's	6 (85.71)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Byrne, AM; Gilmer, JF; Kelleher, D; Long, A; Majer, F; Prichard, D; Sharma, R	1
Asanuma, K; Chen, M; Cheng, E; Huo, X; Peng, S; Pham, TH; Rezaei, D; Souza, RF; Spechler, SJ; Wang, DH; Yu, C; Zhang, Q; Zhang, X	1
Fujimura, T; Fushida, S; Harada, S; Hattori, T; Kinoshita, J; Miyashita, T; Mukaisho, K; Ohta, T; Ojima, E; Oyama, K; Tajima, H; Tsukada, T	1
Abdel-Latif, MM; Inoue, H; Reynolds, JV	1
Burnat, G; Konturek, PC; Majka, J	1
Almada, LL; Buttar, NS; Comba, A; Demars, CJ; Fernández-Zapico, ME; Gainullin, VG; Lomberk, G; Rizvi, S; Rizvi, Z; Wang, K	1
Ajani, J; Buttar, NS; Chen, CT; Chou, CK; Guha, S; Hsu, JM; Huang, P; Hung, MC; Izzo, JG; Kuo, HP; Lee, DF; Sun, HL; Wang, KK; Wei, Y; Wu, TT; Yen, CJ	1

Trials

1 trial(s) available for ursodeoxycholic acid and Esophageal Neoplasms

Article	Year
In Barrett's esophagus patients and Barrett's cell lines, ursodeoxycholic acid increases antioxidant expression and prevents DNA damage by bile acids. American journal of physiology. Gastrointestinal and liver physiology, 2014, Jul-15, Volume: 307, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Anticarcinogenic Agents; Antioxidants; Barrett Esophagus; Catalase; Cell Line; Deoxycholic Acid; DNA Damage; Epithelial Cells; Esophageal Neoplasms; Esophagus; Female; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Histones; Humans; Male; Middle Aged; NF-E2-Related Factor 2; Phosphorylation; RNA Interference; RNA, Messenger; Time Factors; Transcription Factor RelA; Transfection; Treatment Outcome; Up-Regulation; Ursodeoxycholic Acid	2014

Article

Year

In Barrett's esophagus patients and Barrett's cell lines, ursodeoxycholic acid increases antioxidant expression and prevents DNA damage by bile acids.

American journal of physiology. Gastrointestinal and liver physiology, 2014, Jul-15, Volume: 307, Issue:2

Topics: Adult; Aged; Aged, 80 and over; Anticarcinogenic Agents; Antioxidants; Barrett Esophagus; Catalase; Cell Line; Deoxycholic Acid; DNA Damage; Epithelial Cells; Esophageal Neoplasms; Esophagus; Female; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Histones; Humans; Male; Middle Aged; NF-E2-Related Factor 2; Phosphorylation; RNA Interference; RNA, Messenger; Time Factors; Transcription Factor RelA; Transfection; Treatment Outcome; Up-Regulation; Ursodeoxycholic Acid

2014

Other Studies

6 other study(ies) available for ursodeoxycholic acid and Esophageal Neoplasms

Article	Year
Ursodeoxycholic acid amides as novel glucocorticoid receptor modulators. Journal of medicinal chemistry, 2011, Jan-13, Volume: 54, Issue:1 Topics: Amides; Binding Sites; Binding, Competitive; Cell Line, Tumor; Dexamethasone; Esophageal Neoplasms; Fluorescence Resonance Energy Transfer; Glucocorticoids; HEK293 Cells; Humans; Ligands; Models, Molecular; NF-kappa B; Protein Transport; Radioligand Assay; Receptors, Glucocorticoid; Response Elements; Structure-Activity Relationship; Transcriptional Activation; Tumor Necrosis Factor-alpha; Ursodeoxycholic Acid	2011
Chemoprevention of esophageal adenocarcinoma in a rat model by ursodeoxycholic acid. Clinical and experimental medicine, 2015, Volume: 15, Issue:3 Topics: Adenocarcinoma; Animals; Antineoplastic Agents; CDX2 Transcription Factor; Chemoprevention; Disease Models, Animal; Esophageal Neoplasms; Esophagus; Gene Expression Profiling; Histocytochemistry; Homeodomain Proteins; Immunohistochemistry; Male; Microscopy; NF-kappa B; Rats, Wistar; Transcription Factors; Treatment Outcome; Ursodeoxycholic Acid	2015
Opposing effects of bile acids deoxycholic acid and ursodeoxycholic acid on signal transduction pathways in oesophageal cancer cells. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2016, Volume: 25, Issue:5 Topics: Adenocarcinoma; Apoptosis; Cell Proliferation; Cholagogues and Choleretics; Cyclooxygenase 2; Deoxycholic Acid; Esophageal Neoplasms; Humans; NF-kappa B; Signal Transduction; Tumor Cells, Cultured; Ursodeoxycholic Acid	2016
Bile acids are multifunctional modulators of the Barrett's carcinogenesis. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2010, Volume: 61, Issue:2 Topics: Adenocarcinoma; Barrett Esophagus; CDX2 Transcription Factor; Cell Line, Tumor; Cyclooxygenase 2; Deoxycholic Acid; DNA Glycosylases; Down-Regulation; Esophageal Neoplasms; Gene Expression Regulation, Neoplastic; Homeodomain Proteins; Humans; NF-kappa B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Up-Regulation; Ursodeoxycholic Acid	2010
Combinatorial chemoprevention reveals a novel smoothened-independent role of GLI1 in esophageal carcinogenesis. Cancer research, 2010, Sep-01, Volume: 70, Issue:17 Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Aspirin; Barrett Esophagus; Cell Growth Processes; Cyclin-Dependent Kinase 2; Disease Models, Animal; Down-Regulation; Esophageal Neoplasms; Humans; Oncogene Proteins; Promoter Regions, Genetic; Protein Binding; Rats; Trans-Activators; Transfection; Ursodeoxycholic Acid; Zinc Finger Protein GLI1	2010
Bile acid exposure up-regulates tuberous sclerosis complex 1/mammalian target of rapamycin pathway in Barrett's-associated esophageal adenocarcinoma. Cancer research, 2008, Apr-15, Volume: 68, Issue:8 Topics: Adenocarcinoma; Barrett Esophagus; Bile Acids and Salts; Cell Division; Chenodeoxycholic Acid; Esophageal Neoplasms; Gastroesophageal Reflux; Gene Expression Regulation, Neoplastic; Humans; Inflammation; NF-kappa B; Nitriles; Protein Kinases; RNA, Small Interfering; Sirolimus; Sulfones; TOR Serine-Threonine Kinases; Tuberous Sclerosis Complex 1 Protein; Tumor Suppressor Proteins; Ursodeoxycholic Acid	2008