Page last updated: 2024-08-23

ursodeoxycholic acid and Colonic Neoplasms

ursodeoxycholic acid has been researched along with Colonic Neoplasms in 52 studies

Research

Studies (52)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (7.69)	18.7374
1990's	10 (19.23)	18.2507
2000's	28 (53.85)	29.6817
2010's	9 (17.31)	24.3611
2020's	1 (1.92)	2.80

Authors

Authors	Studies
Brossard, D; Clément, M; El Kihel, L; Khalid, M; Rault, S; Roussakis, C; Sebbahi, W	1
Ahuja, N; Cai, Y; Gaule, P; Huang, H; Johnson, CH; Khan, SA; Lu, J; Lu, L; Muca, E; Paty, PB; Rattray, NJW; Rattray, Z; Shen, X; Theriot, CM; Yan, H; Zhang, Y	1
Cho, JH; Kim, E; Kim, EK; Kim, YJ	1
Mothersill, C; Rollo, D; Seymour, C; Vo, NTK; Vukmirovic, D	1
Eaton, JE; Gores, GJ; Lazaridis, KN; Lindor, KD; Talwalkar, JA	1
Centuori, SM; Martinez, JD	1
Alberts, DS; Ashbeck, EL; Jacobs, ET; Martínez, ME; Roe, DJ; Thompson, PA; Wertheim, BC	1
Byrne, AM; Davies, A; Foran, E; Kelleher, D; Long, A; Mahon, C; O'Donoghue, D; O'Sullivan, J; Sharma, R	1
Hanski, C; Hanski, ML; Krishna-Subramanian, S; Lüscher-Firzlaff, J; Peiró-Jordán, R; Zeitz, M	1
Fujii, T; Hirai, T; Kanamoto, R; Okada, S; Saeki, T; Yui, S	1
Arif, M; Ashraf, I; Bechtold, ML; Choudhary, A; Hammad, HT; Matteson, ML; Puli, SR	1
Bissonnette, M; Brasitus, T; Hart, J; Nguyen, L; Sitrin, MD; Stoiber, D; Wali, RK	1
Dominguez, MF; Larena, MG; Macias, RI; Marin, JJ; Martinez-Diez, MC; Serrano, MA	1
Bissonnette, M; Brasitus, T; Cohen, G; Hart, J; Joseph, L; Khare, S; Nguyen, L; Ramaswamy, A; Sitrin, M; Tretiakova, M; Wali, RK; Wang, J; Wen, M	1
Butcher, SK; Lord, JM; McMillan, L; Pongracz, J	1
Keach, J; Kremers, WK; Lindor, KD; Loftus, EV; Pardi, DS	1
Brentnall, TA	1
Bissonnette, M; Boss, GR; Cerda, S; Cohen, G; Hart, J; Joseph, L; Khare, S; Nimmagadda, K; Sitrin, MD; Stoiber, D; Tretiakova, M; von Lintig, FC; Wali, RK	1
Bresalier, RS; Byrd, JC; Koo, JS; Song, S	1
Iwami, K; Kanamoto, R; Saeki, T; Yui, S	1
Abdel-Latif, MM; Arfin, Q; Kelleher, D; Shah, SA; Volkov, Y	1
Kelleher, D; Long, A; Looby, E; Shah, SA; Volkov, Y	1
Fuke, H; Inoue, T; Ito, T; Miyashita, K; Nabeshima, K; Nakano, T; Shiraki, K; Sugimoto, K; Suzuki, M; Takase, K; Yamanaka, T	1
Ballestero, MR; Briz, O; Gonzalez-San Martin, F; Jimenez, F; Marin, JJ; Monte, MJ	1
Akare, S; Chen, W; Jean-Louis, S; Martinez, JD; Powell, AA; Wood, DJ	1
Gatzen, M; Pausch, J	1
Kohno, H; Miyamoto, S; Suzuki, R; Tanaka, T; Wakabayashi, K; Yasui, Y	1
Pérez-Holanda, S; Piñol Felis, C; Rodrigo, L; Viñas Salas, J	1
Kanamoto, R; Saeki, T; Yui, S	1
Bissonnette, M; Cerda, S; Cohen, G; Dougherty, U; Fichera, A; Holgren, C; Jagadeeswaran, S; Joseph, L; Khare, S; Li, YC; Moore, C; Mustafi, R; Samarel, A; Tretiakova, M; Wali, R; Wang, J; Yuan, W	1
Leuschner, U	1
Mamianetti, A	1
Bissonnette, M; Brasitus, TA; Earnest, DL; Frawley, BP; Hartmann, S; Khare, S; Roy, HK; Scaglione-Sewell, BA; Sitrin, MD; Wali, RK	1
Bhattacharyya, AK; Bissonette, M; Brasitus, TA; Earnest, DL; Holubec, H; Jolley, CS; Khare, S; Roy, H; Wali, RK	1
Beste, JE; Ho, SB; Shekels, LL	1
Handa, H; Hiramoto, M; Hirano, F; Makino, I; Makino, Y; Okamoto, K; Tanada, H	1
Cheng, Y; Duan, RD; Nilsson, A; Tauschel, HD	1
Coleman, JP; Heuman, DM; Hylemon, PB; Kirby, LC; Pandak, M; Setchell, KD; Vlahcevic, ZR	1
Fukaura, Y; Narisawa, T; Sekiguchi, H; Terada, K	2
Hirabayashi, N; Ikegami, T; Kano, M; Matsuzaki, Y; Shoda, J; Tanaka, N	1
Benz, C; Sauer, P; Stiehl, A	1
Brentnall, TA; Bronner, MP; Emond, MJ; Haggitt, RC; Kimmey, MB; Kowdley, KV; Tung, BY	1
Hawk, ET; Viner, JL	1
Kim, HS	1
Lee, SD; Surawicz, CM	1
Fukaura, Y; Nakai, K; Narisawa, T; Takeba, N	1
Houchi, H; Momen, MA; Monden, Y; Umemoto, A	1
Breuer, NF; Dommes, P; Goebell, H; Jaekel, S	1
Classen, M; Kurtz, WJ; Leuschner, U; Strohm, WD	1

Reviews

7 review(s) available for ursodeoxycholic acid and Colonic Neoplasms

Article	Year
Pathogenesis of primary sclerosing cholangitis and advances in diagnosis and management. Gastroenterology, 2013, Volume: 145, Issue:3 Topics: Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cholagogues and Choleretics; Cholangiocarcinoma; Cholangiopancreatography, Endoscopic Retrograde; Cholangitis, Sclerosing; Colonic Neoplasms; Combined Modality Therapy; Diagnosis, Differential; Gallbladder Neoplasms; Genetic Predisposition to Disease; Humans; Immunity, Innate; Immunosuppressive Agents; Intestines; Liver Transplantation; Metagenome; Ursodeoxycholic Acid	2013
Differential regulation of EGFR-MAPK signaling by deoxycholic acid (DCA) and ursodeoxycholic acid (UDCA) in colon cancer. Digestive diseases and sciences, 2014, Volume: 59, Issue:10 Topics: Colonic Neoplasms; Deoxycholic Acid; ErbB Receptors; Humans; Mitogen-Activated Protein Kinase Kinases; Signal Transduction; Ursodeoxycholic Acid	2014
Ursodeoxycholic acid in patients with ulcerative colitis and primary sclerosing cholangitis for prevention of colon cancer: a meta-analysis. Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2012, Volume: 31, Issue:2 Topics: Adenoma; Cholagogues and Choleretics; Cholangitis, Sclerosing; Colitis, Ulcerative; Colonic Neoplasms; Humans; Ursodeoxycholic Acid	2012
Ursodiol: good drug makes good. Gastroenterology, 2003, Volume: 124, Issue:4 Topics: Cholagogues and Choleretics; Colonic Neoplasms; Humans; Ursodeoxycholic Acid	2003
[Treatment of cholestatic hepatic diseases: more than the substitution of fat soluble vitamins?]. Der Internist, 2006, Volume: 47, Issue:12 Topics: Adult; Age Factors; Bile Acids and Salts; Bile Duct Neoplasms; Cholangiocarcinoma; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Infant; Infant, Newborn; Liver Cirrhosis, Biliary; Long-Term Care; Middle Aged; Pregnancy; Risk Factors; Ursodeoxycholic Acid	2006
Current problem of chemical gallstone dissolution. The Tokai journal of experimental and clinical medicine, 1983, Volume: 8, Issue:2 Topics: Animals; Calcinosis; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Colonic Neoplasms; Cost-Benefit Analysis; Deoxycholic Acid; Diarrhea; Female; Humans; Liver; Macaca mulatta; Male; Transaminases; Ursodeoxycholic Acid	1983
Primary sclerosing cholangitis. Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2000, Volume: 14, Issue:4 Topics: Bile Duct Neoplasms; Bile Ducts; Cholagogues and Choleretics; Cholangitis, Sclerosing; Colonic Neoplasms; Constriction, Pathologic; Humans; Liver Transplantation; Ursodeoxycholic Acid	2000

Trials

2 trial(s) available for ursodeoxycholic acid and Colonic Neoplasms

Article	Year
Physical activity as a determinant of fecal bile acid levels. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2009, Volume: 18, Issue:5 Topics: Adenoma; Aged; Bile Acids and Salts; Cholagogues and Choleretics; Colonic Neoplasms; Double-Blind Method; Feces; Female; Humans; Linear Models; Male; Middle Aged; Motor Activity; Neoplasm Recurrence, Local; Risk Factors; Ursodeoxycholic Acid	2009
Ursodeoxycholic acid as a chemopreventive agent in patients with ulcerative colitis and primary sclerosing cholangitis. Gastroenterology, 2003, Volume: 124, Issue:4 Topics: Adult; Aged; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Cholagogues and Choleretics; Cholangitis, Sclerosing; Colitis, Ulcerative; Colonic Neoplasms; Disease-Free Survival; Female; Folic Acid; Humans; Incidence; Male; Middle Aged; Risk Factors; Ursodeoxycholic Acid	2003

Article

Year

Physical activity as a determinant of fecal bile acid levels.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2009, Volume: 18, Issue:5

Topics: Adenoma; Aged; Bile Acids and Salts; Cholagogues and Choleretics; Colonic Neoplasms; Double-Blind Method; Feces; Female; Humans; Linear Models; Male; Middle Aged; Motor Activity; Neoplasm Recurrence, Local; Risk Factors; Ursodeoxycholic Acid

2009

Ursodeoxycholic acid as a chemopreventive agent in patients with ulcerative colitis and primary sclerosing cholangitis.

Gastroenterology, 2003, Volume: 124, Issue:4

Topics: Adult; Aged; Aminosalicylic Acids; Anti-Inflammatory Agents, Non-Steroidal; Cholagogues and Choleretics; Cholangitis, Sclerosing; Colitis, Ulcerative; Colonic Neoplasms; Disease-Free Survival; Female; Folic Acid; Humans; Incidence; Male; Middle Aged; Risk Factors; Ursodeoxycholic Acid

2003

Other Studies

43 other study(ies) available for ursodeoxycholic acid and Colonic Neoplasms

Article	Year
Synthesis of bile acid derivatives and in vitro cytotoxic activity with pro-apoptotic process on multiple myeloma (KMS-11), glioblastoma multiforme (GBM), and colonic carcinoma (HCT-116) human cell lines. European journal of medicinal chemistry, 2010, Volume: 45, Issue:7 Topics: Apoptosis; Bile Acids and Salts; Cell Line, Tumor; Colonic Neoplasms; Glioblastoma; Humans; Multiple Myeloma; Piperazine; Piperazines	2010
Bile acid distributions, sex-specificity, and prognosis in colorectal cancer. Biology of sex differences, 2022, 10-23, Volume: 13, Issue:1 Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Colonic Neoplasms; Colorectal Neoplasms; Female; Forkhead Transcription Factors; Glycochenodeoxycholic Acid; Humans; Lithocholic Acid; Male; Sex Distribution; Ursodeoxycholic Acid	2022
Ursodeoxycholic acid inhibits the proliferation of colon cancer cells by regulating oxidative stress and cancer stem-like cell growth. PloS one, 2017, Volume: 12, Issue:7 Topics: Cell Cycle Checkpoints; Cell Proliferation; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; HCT116 Cells; HT29 Cells; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplastic Stem Cells; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; RNA, Messenger; Ursodeoxycholic Acid	2017
Characterization of Radioprotective, Radiomitigative and Bystander Signaling Modulating Effects of Endogenous Metabolites - Phenylacetate, Ursodeoxycholate and Tauroursodeoxycholate - on HCT116 Human Colon Carcinoma Cell Line. Radiation research, 2019, Volume: 192, Issue:1 Topics: Acetates; Bystander Effect; Cell Survival; Colonic Neoplasms; Dose-Response Relationship, Radiation; HCT116 Cells; Humans; Phenols; Radiation-Protective Agents; Signal Transduction; Taurochenodeoxycholic Acid; Ursodeoxycholic Acid	2019
Bile acids modulate the Golgi membrane fission process via a protein kinase Ceta and protein kinase D-dependent pathway in colonic epithelial cells. Carcinogenesis, 2010, Volume: 31, Issue:4 Topics: Bile Acids and Salts; Colitis, Ulcerative; Colonic Neoplasms; Deoxycholic Acid; Dexamethasone; Golgi Apparatus; HCT116 Cells; Humans; Phosphorylation; Protein Kinase C; Receptors, Glucocorticoid; Ursodeoxycholic Acid	2010
The chemopreventive agent ursodeoxycholic acid inhibits proliferation of colon carcinoma cells by suppressing c-Myc expression. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2012, Volume: 21, Issue:5 Topics: Antineoplastic Agents; Carcinoma; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; HCT116 Cells; Humans; Proto-Oncogene Proteins c-myc; Ursodeoxycholic Acid	2012
Ursodeoxycholic acid protects colon cancer HCT116 cells from deoxycholic acid-induced apoptosis by inhibiting apoptosome formation. Nutrition and cancer, 2012, Volume: 64, Issue:4 Topics: Apoptosis; Apoptosomes; Apoptotic Protease-Activating Factor 1; Caspase 9; Caspase Inhibitors; Colonic Neoplasms; Deoxycholic Acid; HCT116 Cells; Humans; Mitochondria; Proto-Oncogene Proteins c-akt; Ursodeoxycholic Acid; X-Linked Inhibitor of Apoptosis Protein	2012
Ursodeoxycholic acid inhibits the initiation and postinitiation phases of azoxymethane-induced colonic tumor development. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2002, Volume: 11, Issue:11 Topics: Animals; Azoxymethane; Cholagogues and Choleretics; Colonic Neoplasms; Disease Models, Animal; Disease Progression; Dose-Response Relationship, Drug; Incidence; Male; Rats; Rats, Inbred F344; Time Factors; Treatment Outcome; Ursodeoxycholic Acid	2002
Relationship between tumor cell load and sensitivity to the cytostatic effect of two novel platinum-bile acid complexes, Bamet-D3 and Bamet-UD2. Journal of drug targeting, 2002, Volume: 10, Issue:5 Topics: Animals; Antineoplastic Agents; Bile Acids and Salts; Cell Division; Cell Survival; Colonic Neoplasms; Humans; Liver Neoplasms; Mice; Organoplatinum Compounds; Rats; Tumor Cells, Cultured; Ursodeoxycholic Acid	2002
Ursodeoxycholic acid and F(6)-D(3) inhibit aberrant crypt proliferation in the rat azoxymethane model of colon cancer: roles of cyclin D1 and E-cadherin. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2002, Volume: 11, Issue:12 Topics: Animals; Azoxymethane; Base Sequence; Biomarkers, Tumor; Biopsy, Needle; Blotting, Western; Cadherins; Cell Division; Cholecalciferol; Colonic Neoplasms; Cyclin D1; Disease Models, Animal; Immunohistochemistry; Injections, Intraperitoneal; Intestinal Mucosa; Male; Molecular Sequence Data; Neoplasms, Experimental; Polymerase Chain Reaction; Random Allocation; Rats; Rats, Inbred F344; Reference Values; RNA, Messenger; Sensitivity and Specificity; Ursodeoxycholic Acid	2002
Opposing effects of butyrate and bile acids on apoptosis of human colon adenoma cells: differential activation of PKC and MAP kinases. British journal of cancer, 2003, Mar-10, Volume: 88, Issue:5 Topics: Adenoma; Apoptosis; Butyric Acid; Caspase 3; Caspase Inhibitors; Colonic Neoplasms; Cysteine Proteinase Inhibitors; Enzyme Activation; Humans; Isoenzymes; Mitogen-Activated Protein Kinases; Protein Kinase C; Ursodeoxycholic Acid	2003
Ursodeoxycholic acid inhibits Ras mutations, wild-type Ras activation, and cyclooxygenase-2 expression in colon cancer. Cancer research, 2003, Jul-01, Volume: 63, Issue:13 Topics: Animals; Azoxymethane; Colonic Neoplasms; Cyclooxygenase 2; Gene Expression Regulation, Neoplastic; Genes, ras; Isoenzymes; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transcription, Genetic; Ursodeoxycholic Acid	2003
Bile acids induce MUC2 overexpression in human colon carcinoma cells. Cancer, 2005, Apr-15, Volume: 103, Issue:8 Topics: Antineoplastic Agents; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholic Acids; Colonic Neoplasms; Curcumin; Deoxycholic Acid; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Mitogen-Activated Protein Kinases; Mucin-2; Mucins; Naphthalenes; Promoter Regions, Genetic; Protein Kinase C; RNA, Messenger; Transcription Factor AP-1; Transcription, Genetic; Transcriptional Activation; Tumor Cells, Cultured; Up-Regulation; Ursodeoxycholic Acid	2005
Characteristics of apoptosis in HCT116 colon cancer cells induced by deoxycholic acid. Journal of biochemistry, 2005, Volume: 138, Issue:2 Topics: Apoptosis; Caspase 9; Caspases; Colonic Neoplasms; Cytochromes c; Deoxycholic Acid; HCT116 Cells; Humans; Hydrophobic and Hydrophilic Interactions; Mitochondria; Ursodeoxycholic Acid	2005
Ursodeoxycholic acid inhibits interleukin 1 beta [corrected] and deoxycholic acid-induced activation of NF-kappaB and AP-1 in human colon cancer cells. International journal of cancer, 2006, Feb-01, Volume: 118, Issue:3 Topics: Binding Sites; Blotting, Western; Cholagogues and Choleretics; Colonic Neoplasms; Deoxycholic Acid; Electrophoretic Mobility Shift Assay; HCT116 Cells; Humans; Interleukin-1; NF-kappa B; Protein Kinase C; Transcription Factor AP-1; Ursodeoxycholic Acid	2006
Ursodeoxycholic acid inhibits translocation of protein kinase C in human colonic cancer cell lines. European journal of cancer (Oxford, England : 1990), 2005, Volume: 41, Issue:14 Topics: Anticarcinogenic Agents; Blotting, Western; Cell Line, Tumor; Cell Shape; Colonic Neoplasms; Deoxycholic Acid; Green Fluorescent Proteins; Humans; Protein Kinase C; Tetradecanoylphorbol Acetate; Transfection; Ursodeoxycholic Acid	2005
Different effects of bile acids, ursodeoxycholic acid and deoxycholic acid, on cell growth and cell death in human colonic adenocarcinoma cells. International journal of molecular medicine, 2005, Volume: 16, Issue:4 Topics: Adenocarcinoma; Apoptosis; Bile Acids and Salts; Cell Cycle; Cell Proliferation; Colonic Neoplasms; Deoxycholic Acid; Dose-Response Relationship, Drug; Flow Cytometry; HT29 Cells; Humans; Time Factors; Ursodeoxycholic Acid	2005
Expression of transporters potentially involved in the targeting of cytostatic bile acid derivatives to colon cancer and polyps. Biochemical pharmacology, 2006, Sep-14, Volume: 72, Issue:6 Topics: Animals; Bile Acids and Salts; Colonic Neoplasms; Drug Delivery Systems; Humans; Membrane Transport Proteins; Organic Anion Transporters, Sodium-Dependent; Organic Anion Transporters, Sodium-Independent; Organic Cation Transporter 1; Organoplatinum Compounds; Polyps; Solute Carrier Organic Anion Transporter Family Member 1B3; Symporters; Ursodeoxycholic Acid; Xenopus laevis	2006
[Primary sclerosing cholangitis. To slow progression and reduce carcinoma risk]. MMW Fortschritte der Medizin, 2006, Jun-15, Volume: 148, Issue:24 Topics: Adult; Cholagogues and Choleretics; Cholangitis, Sclerosing; Colonic Neoplasms; Colorectal Neoplasms; Humans; Placebos; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Factors; Tablets; Time Factors; Ursodeoxycholic Acid	2006
Ursodeoxycholic acid modulates histone acetylation and induces differentiation and senescence. International journal of cancer, 2006, Dec-15, Volume: 119, Issue:12 Topics: Acetylation; Apoptosis; Butyrates; Cadherins; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell Shape; Cell Size; Cellular Senescence; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Dose-Response Relationship, Drug; HCT116 Cells; Histones; HT29 Cells; Humans; Inhibitor of Apoptosis Proteins; Keratin-18; Keratin-19; Keratin-8; Retinoblastoma Protein; Tumor Suppressor Protein p53; Up-Regulation; Ursodeoxycholic Acid	2006
Ursodeoxycholic acid versus sulfasalazine in colitis-related colon carcinogenesis in mice. Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Apr-15, Volume: 13, Issue:8 Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Colitis; Colonic Neoplasms; Cyclooxygenase 2; Disease Models, Animal; Male; Mice; Mice, Inbred ICR; RNA, Messenger; Sulfasalazine; Ursodeoxycholic Acid	2007
[Effect of ursodeoxycholic acid in an experimental colon cancer model]. Revista espanola de enfermedades digestivas, 2007, Volume: 99, Issue:9 Topics: Animals; Cholagogues and Choleretics; Colonic Neoplasms; Disease Models, Animal; Female; Male; Rats; Rats, Sprague-Dawley; Ursodeoxycholic Acid	2007
Deoxycholic acid can induce apoptosis in the human colon cancer cell line HCT116 in the absence of Bax. Nutrition and cancer, 2008, Volume: 60, Issue:1 Topics: Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 8; Caspase 9; Caspases; Colonic Neoplasms; Deoxycholic Acid; Enzyme Activation; HCT116 Cells; Humans; Ursodeoxycholic Acid	2008
Ursodeoxycholic acid suppresses Cox-2 expression in colon cancer: roles of Ras, p38, and CCAAT/enhancer-binding protein. Nutrition and cancer, 2008, Volume: 60, Issue:3 Topics: Animals; Azoxymethane; CCAAT-Enhancer-Binding Protein-beta; Cells, Cultured; Chemoprevention; Cholic Acid; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dietary Supplements; Gene Expression Regulation, Neoplastic; Genes, ras; p38 Mitogen-Activated Protein Kinases; Signal Transduction; Transcription Factors; Transfection; Ursodeoxycholic Acid	2008
[Current treatment of gallbladder calculi]. Acta gastroenterologica Latinoamericana, 1984, Volume: 14, Issue:4 Topics: Animals; Chenodeoxycholic Acid; Cholecystectomy; Cholelithiasis; Cholesterol; Colonic Neoplasms; Deoxycholic Acid; Female; Humans; Male; Risk; Ursodeoxycholic Acid	1984
Mechanism of action of chemoprotective ursodeoxycholate in the azoxymethane model of rat colonic carcinogenesis: potential roles of protein kinase C-alpha, -beta II, and -zeta. Cancer research, 1995, Nov-15, Volume: 55, Issue:22 Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Cholic Acid; Cholic Acids; Colonic Neoplasms; Isoenzymes; Male; Protein Kinase C; Rats; Rats, Inbred F344; Ursodeoxycholic Acid	1995
Chemoprevention of azoxymethane-induced colonic carcinogenesis by supplemental dietary ursodeoxycholic acid. Cancer research, 1994, Oct-01, Volume: 54, Issue:19 Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Colonic Neoplasms; Diet; Male; Rats; Rats, Inbred F344; Ursodeoxycholic Acid	1994
Tauroursodeoxycholic acid protects in vitro models of human colonic cancer cells from cytotoxic effects of hydrophobic bile acids. The Journal of laboratory and clinical medicine, 1996, Volume: 127, Issue:1 Topics: Bile Acids and Salts; Carcinoma; Cell Division; Colonic Neoplasms; Cytotoxins; Humans; Taurodeoxycholic Acid; Tumor Cells, Cultured; Ursodeoxycholic Acid	1996
Induction of the transcription factor AP-1 in cultured human colon adenocarcinoma cells following exposure to bile acids. Carcinogenesis, 1996, Volume: 17, Issue:3 Topics: Activating Transcription Factor 1; Adenocarcinoma; Base Sequence; Bile Acids and Salts; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholic Acid; Cholic Acids; Colonic Neoplasms; Deoxycholic Acid; DNA Primers; DNA-Binding Proteins; DNA, Neoplasm; Enzyme Activation; Gene Expression Regulation; Genetic Vectors; Humans; Lithocholic Acid; Molecular Sequence Data; NF-kappa B; Podophyllin; Podophyllotoxin; Protein Kinase C; Tetradecanoylphorbol Acetate; Transcription Factor AP-1; Transcription Factors; Tumor Cells, Cultured; Ursodeoxycholic Acid	1996
Clinical development plan: ursodiol. Journal of cellular biochemistry. Supplement, 1996, Volume: 26 Topics: Animals; Anticarcinogenic Agents; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Colonic Neoplasms; Drug Approval; Female; Humans; Male; Rats; Research Design; Ursodeoxycholic Acid	1996
Effects of ursodeoxycholate and other bile salts on levels of rat intestinal alkaline sphingomyelinase: a potential implication in tumorigenesis. Digestive diseases and sciences, 1998, Volume: 43, Issue:1 Topics: Administration, Oral; Animals; Bile Acids and Salts; Cholic Acids; Colonic Neoplasms; Glycochenodeoxycholic Acid; Glycocholic Acid; Intestinal Mucosa; Rats; Rats, Sprague-Dawley; Sphingomyelin Phosphodiesterase; Taurocholic Acid; Taurodeoxycholic Acid; Ursodeoxycholic Acid	1998
Metabolic fate and hepatocyte toxicity of reverse amide analogs of conjugated ursodeoxycholate in the rat. The Journal of steroid biochemistry and molecular biology, 1998, Volume: 64, Issue:1-2 Topics: Animals; Bacteria; Bile; Biological Transport, Active; Cell Survival; Cells, Cultured; Colon; Colonic Neoplasms; Enterohepatic Circulation; Half-Life; Hydrolysis; Intestinal Mucosa; Intestines; Liver; Male; Rats; Rats, Sprague-Dawley; Ursodeoxycholic Acid	1998
Prevention of N-methylnitrosourea-induced colon tumorigenesis by ursodeoxycholic acid in F344 rats. Japanese journal of cancer research : Gann, 1998, Volume: 89, Issue:10 Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogens; Colonic Neoplasms; Dose-Response Relationship, Drug; Female; Methylnitrosourea; Rats; Rats, Inbred F344; Time Factors; Ursodeoxycholic Acid	1998
The chemopreventive role of ursodeoxycholic acid in azoxymethane-treated rats: suppressive effects on enhanced group II phospholipase A2 expression in colonic tissue. Cancer letters, 1998, Dec-25, Volume: 134, Issue:2 Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogens; Colonic Neoplasms; DNA Primers; Gastrointestinal Agents; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Immunoblotting; Male; Phospholipases A; Phospholipases A2; Precancerous Conditions; Prostaglandins; Random Allocation; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Ursodeoxycholic Acid	1998
Inhibitory effects of ursodeoxycholic acid on N-methylnitrosourea-induced colon carcinogenesis and colonic mucosal telomerase activity in F344 rats. Journal of experimental & clinical cancer research : CR, 1999, Volume: 18, Issue:2 Topics: Animals; Antineoplastic Agents; Carcinogens; Colon; Colonic Neoplasms; Enzyme Inhibitors; Female; Gastrointestinal Agents; Intestinal Mucosa; Methylnitrosourea; Rats; Rats, Inbred F344; Telomerase; Ursodeoxycholic Acid	1999
Ursodiol use is associated with lower prevalence of colonic neoplasia in patients with ulcerative colitis and primary sclerosing cholangitis. Annals of internal medicine, 2001, Jan-16, Volume: 134, Issue:2 Topics: Adult; Cholagogues and Choleretics; Cholangitis, Sclerosing; Colitis, Ulcerative; Colon; Colonic Neoplasms; Colonoscopy; Cross-Sectional Studies; Female; Humans; Male; Precancerous Conditions; Risk Factors; Ursodeoxycholic Acid	2001
Chemoprevention in ulcerative colitis: narrowing the gap between clinical practice and research. Annals of internal medicine, 2001, Jan-16, Volume: 134, Issue:2 Topics: Cholagogues and Choleretics; Cholangitis, Sclerosing; Colitis, Ulcerative; Colon; Colonic Neoplasms; Humans; Precancerous Conditions; Ursodeoxycholic Acid	2001
Prevention of colon cancer with ursodiol in ulcerative colitis. Inflammatory bowel diseases, 2001, Volume: 7, Issue:3 Topics: Cholagogues and Choleretics; Cholangitis, Sclerosing; Colitis, Ulcerative; Colonic Neoplasms; Humans; Prevalence; Ursodeoxycholic Acid	2001
Ursodiol for all? The American journal of gastroenterology, 2001, Volume: 96, Issue:12 Topics: Cholagogues and Choleretics; Cholangitis, Sclerosing; Colitis, Ulcerative; Colonic Neoplasms; Cross-Sectional Studies; Humans; Retrospective Studies; Ursodeoxycholic Acid	2001
Chemoprevention of N-methylnitrosourea-induced colon carcinogenesis by ursodeoxycholic acid-5-aminosalicylic acid conjugate in F344 rats. Japanese journal of cancer research : Gann, 2002, Volume: 93, Issue:2 Topics: Animals; Anticarcinogenic Agents; Bile Acids and Salts; Colonic Neoplasms; Female; Mesalamine; Methylnitrosourea; Precancerous Conditions; Rats; Rats, Inbred F344; Ursodeoxycholic Acid	2002
Effect of ursodeoxycholic acid on azoxymethane-induced aberrant crypt foci formation in rat colon: in vitro potential role of intracellular Ca2+. The journal of medical investigation : JMI, 2002, Volume: 49, Issue:1-2 Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Bile Acids and Salts; Calcium; Calcium Signaling; Carcinogens; Colon; Colonic Neoplasms; Diet; Disease Models, Animal; Dose-Response Relationship, Drug; Intracellular Fluid; Male; Rats; Rats, Inbred F344; Tumor Cells, Cultured; Ursodeoxycholic Acid	2002
Fecal bile acid excretion pattern in colonic cancer patients. Digestive diseases and sciences, 1985, Volume: 30, Issue:9 Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholic Acid; Cholic Acids; Colonic Neoplasms; Deoxycholic Acid; Feces; Female; Humans; Intestinal Mucosa; Lithocholic Acid; Male; Middle Aged; Ursodeoxycholic Acid	1985
Ileal and colonic mucosal bile acids in Crohn's disease and right colonic carcinoma. The Tokai journal of experimental and clinical medicine, 1985, Volume: 10, Issue:1 Topics: Adolescent; Adult; Aged; Bile Acids and Salts; Chenodeoxycholic Acid; Cholic Acids; Colon; Colonic Neoplasms; Crohn Disease; Deoxycholic Acid; Female; Humans; Ileitis; Ileum; Intestinal Mucosa; Lithocholic Acid; Male; Middle Aged; Ursodeoxycholic Acid	1985