Page last updated: 2024-08-23

ursodeoxycholic acid and Bile Duct Obstruction

ursodeoxycholic acid has been researched along with Bile Duct Obstruction in 377 studies

Research

Studies (377)

TimeframeStudies, this research(%)All Research%
pre-19909 (2.39)18.7374
1990's116 (30.77)18.2507
2000's94 (24.93)29.6817
2010's105 (27.85)24.3611
2020's53 (14.06)2.80

Authors

AuthorsStudies
Green, RM; Hoda, F; Ward, KL1
Camaioni, E; Clerici, C; Costantino, G; Fiorucci, S; Maloney, PR; Morelli, A; Parks, DJ; Pellicciari, R; Willson, TM1
Assis, DN; Barbier, O; Boyer, JL; Gallucci, GM; Ghonem, NS; Hemme, C; Trottier, J1
Cen, Y; Li, M; Wang, Z; Zeng, L1
Colomé Rivero, G; García Romero, R; Martín de Carpi, J; Martorell Sampol, L; Mínguez Rodríguez, B; Molera Busoms, C1
Chang, LW; Chen, LL; Liu, SY; Liu, W; Wang, J; Xie, M1
Mankongpaisarnrung, C; McCashland, TM; Olivera-Martinez, MA; Rajendiran, G1
Areia, AL; Melo, D; Moura, P1
Bruneau, A; Guillot, A; Tacke, F1
Mayo, MJ1
Agirre-Lizaso, A; Aspichueta, P; Banales, JM; Bujanda, L; Echebarria, A; Esparza-Baquer, A; González-Romero, F; Hijona, E; Huici-Izagirre, M; Labiano, I; Luedde, T; Mann, DA; Marin, JJG; Marzioni, M; Milkiewicz, M; Milkiewicz, P; Monte, MJ; Olaizola, I; Olaizola, P; Perugorria, MJ; Rodrigues, PM; Sharif, O; Vucur, M1
Ge, T; Li, D; Wang, Y; Xiao, Y; Yu, L; Zhang, T1
Delija, B; Filipec Kanizaj, T; Lalovac, M; Martincevic, D; Mijic, M; Radetic, E; Saric, I; Sobocan, N1
Harpavat, S; Hernandez, J; Hicks, MJ; Killelea, P; Sakhuja, S1
Bloks, VW; de Boer, JF; de Vries, HD; Hovingh, MV; Koehorst, M; Kuipers, F; Li, R; Mulder, NL; Palmiotti, A; van Zutphen, T1
Chai, J; Fu, L; Peng, S; Tao, L; Wang, H; Zhang, J; Zhang, X; Zhao, N; Zhou, Z1
Lei, L; Li, Z; Ling, L; Liu, Y; Shao, Y; Xiong, Z1
John, BV; Mansour, N; Shaker, M1
Manns, MP; Nevens, F; Trauner, M1
Beuers, U; Trampert, DC1
Ichikawa, H; Iwasa, Y; Iwashita, T; Iwata, K; Iwata, S; Maruta, A; Mita, N; Mukai, T; Ohashi, Y; Okuno, M; Shimizu, M; Tezuka, R; Tomita, E; Uemura, S; Yoshida, K1
Fejfar, T; Hůlek, P; Kaslová, B; Pařízek, A; Petr, T; Šimják, P; Vítek, L1
Hirai, K; Honda, K; Murahashi, M; Takaki, Y1
Chen, Y; Duan, Y; Han, J; Liu, L; Yang, S; Yang, X; Zhang, S1
Baiocchi, L; Grassi, G; Lenci, I; Milana, M; Signorello, A1
Chen, J; Huang, L; Jiang, X; Lan, K; Li, S; Zeng, L; Zhang, L; Zhu, Y1
Bowlus, CL; Kowdley, KV; Levy, C; Mayo, MJ; Pratt, DS; Vuppalanchi, R; Younossi, ZM1
Hirschfield, G; Levy, C; Manns, M1
Kim, KA1
Barba Bernal, R; Bonder, A; Castro, CM; Ferrigno, B; Goyes, D; Medina Morales, E; Patwardhan, VR; Trivedi, H1
Bogdanos, DP; Rigopoulou, EI1
John, BV; Levy, C; Trivella, J1
Gao, L; He, X; Leung, PSC; Rojas, M; Yang, Y1
Chen, W; Li, J; Li, W; Liu, W; Niu, X; Song, Y; Tu, P; Zhao, C1
Cattaneo, M; Hurtado, C; Poniachik, J; Ramírez, F; Roblero, JP; Urzúa, Á1
Fickert, P; Wagner, M1
Feng, W; Hao, Z; Liu, Y; Ren, L; Song, Q; Zhang, L1
Combalia, A; Dubreuil, M; Guañabens, N; Jurado, S; Monegal, A; Parés, A; Peris, P; Ruiz-Gaspà, S1
Fujioka, M; Genda, T; Hara, M; Iwakami, N; Iwakami, SI; Kurokawa, K; Miyashita, Y; Sasaki, S; Takahashi, K1
Bailey, S; Boolchandani, H; Caprio, M; Desai, P; Kazmi, SH; Mally, P1
Fernando, G; Preston, N1
Fickert, P; Jungwirth, E; Kolb-Lenz, D; Krones, E; Lee, JM; Marschall, HU; Moore, DD; Panzitt, K; Pollheimer, M; Thallinger, GG; Thorell, A; Trauner, M; Wagner, M; Xiao, R1
Huang, WC; Lin, CK1
Muriithi, FG1
Abd El Baky, HEH; Badr, AM; Basanti, CWS; Draz, IH; El Sorogy, STM; Kotb, MA; Mosallam, D1
Bernard, O; Jacquemin, E; Lykavieris, P1
Corpechot, C; Montano-Loza, AJ1
Chappell, LC; Hague, WM; Middleton, P; Thornton, JG; Walker, KF1
Alvaro, D; Carpino, G; Craxi, A; Floreani, A; Invernizzi, P; Moschetta, A1
García-Alix Pérez, A; Izurieta Pacheco, AC; Molera Busoms, C; Monfort Carretero, L; Prat Torres, C1
Fejfar, T; Hůlek, P; Vaňásek, T1
Tanaka, A1
Caldez, MJ; Hunziker, W; Kaldis, P; Kausalya, PJ; Mohamed Ali, S; Ong, AGM; Van Hul, N; Woo, WL; Xu, J; Xu, S1
Arab, JP; Candia, R; Kulkarni, AV; Kumar, P; Padaki, NR; Premkumar, M; Reddy, DN; Sharma, M; Tevethia, HV1
Bittencourt, PL; Braga, MH; Cançado, ELR; Cançado, GGL; Codes, L; Coral, GP; Couto, CA; Cunha-Silva, M; da Cunha, SMCF; de Almeida E Borges, VF; de Faria Gomes, NM; de Lima Pace, FH; Faria, LC; Ferraz, MLG; Ivantes, CAP; Levy, C; Mendes, LSC; Nardelli, MJ; Oliveira, EMG; Oliveira, MB; Pessoa, MG; Rotman, V; Signorelli, IV; Terrabuio, DRB; Villela-Nogueira, CA1
Barbier, O; Cieślak, A; Gobeil, S; Perreault, M; Thérien, A; Trottier, J; Verreault, M; Vohl, MC1
Altorjay, I; Bergquist, A; Chapman, R; Denk, G; Färkkilä, M; Fickert, P; Greinwald, R; Halilbasic, E; Hirschfield, GM; Manns, MP; Marschall, HU; Nevens, F; Pröls, M; Reiter, FP; Schramm, C; Schrumpf, E; Spengler, U; Tornai, I; Trauner, M; Trivedi, P1
Alvaro, D; Canonico, PL; Carbone, M; Craxi, A; Floreani, A; Gardini, I; Gasbarrini, A; Invernizzi, P; Kruger, P; Lanati, E; Marzioni, M; Mennini, FS; Muratori, L; Ronco, V; Vespasiani Gentilucci, U1
Debray, D; Gonzales, E; Thébaut, A1
Dickson, I1
Chazouillères, O1
Choe, YH; Kim, J; Paik, N; Paik, YH; Yang, B1
Beuers, U; Hohenester, S1
Fickert, P; Krones, E; Pollheimer, MJ; Rosenkranz, AR1
Adeyemi, O; Alvarez-Laviada, A; Glukhov, AV; Gorelik, J; Ibrahim, E; Schultz, F; Trauner, M; Williamson, C1
Dalekos, GN; Gatselis, NK; Lygoura, V; Polychronopoulou, E1
Minuk, GY; Pollock, G; Uhanova, J1
Alaca, N; Çağlayan Yeğen, B; Kurtel, H; Öktem, G; Özbeyli, D; Şahin, HH; Uslu, S; Yiğittürk, G1
Boatto, G; Burrai, L; Chegaev, K; Di Guida, F; Lama, A; Lazzarato, L; Magliocca, S; Meli, R; Mollica, MP; Nieddu, M; Pirozzi, C; Raso, GM; Rimoli, MG; Russo, R; Santoro, A; Sodano, F1
Cai, X; Chen, ZL; Jin, F; Li, G; Li, HR; Luo, L; Ma, Q; Wang, Y; Xue, J; Yang, F; Zhao, L; Zhou, X1
Jansen, PLM1
Coffey, A; Leung, DH; Quintanilla, NM1
Aziz, K; Breton, E; Chailloux, P; Cousin, E; Cousin, I1
Baumann, U; Beerbaum, P; Hohmann, D; Junge, C; Junge, N; Leiskau, C; Pfister, ED; Schröder, J1
Chi, HY; Choi, MK; Choi, YA; Kang, YJ; Kim, MJ; Kwon, M; Shim, CK; Song, IS; Yoo, HH1
Goldstein, J; Levy, C1
Chambers, S; Jansen, E; Nikolova, V; Papacleovoulou, G; Pataia, V; Poston, L; Samuelsson, AM; Taylor, PD; Williamson, C1
Düll, MM; Kremer, AE1
Floreani, A; Grattagliano, I; Portincasa, P; Ubaldi, E1
Ares, GJ; Buonpane, CL; Cohran, VC; Englert, EG; Helenowski, I; Hunter, CJ1
Amelung, L; Arends, JE; de Bruijne, J; Leoni, MC; Lieveld, FI; van den Brink, J; van Erpecum, CP; van Erpecum, KJ1
Aguilera, L; Albillos, A; Martínez, J1
Abu Backer, F; Abu Mouch, S; Mari, A1
Han, Y; Jia, G; Yuan, Z1
Khan, MN; Middleton, JP; Niccum, M; Syed, S; Vergales, BD1
Carey, EJ; Yokoda, RT1
Andermatten, RB; Barosso, IR; Basiglio, CL; Ciriaci, N; Maidagan, PM; Martín, PL; Razori, MV; Roma, MG; Ruiz, ML; Sánchez Pozzi, EJ1
Arab, JP; Arrese, M; Cabrera, D1
Amano, N; Genda, T; Harada, K; Iijima, K; Matsumoto, K; Murata, A; Sato, S; Shimada, Y; Tomishima, K; Tsuzura, H1
Baghdasaryan, A; Halilbasic, E; Trauner, M1
Alvarez, L; Combalia, A; Dubreuil, M; Guañabens, N; Monegal, A; Parés, A; Peris, P; Ruiz-Gaspà, S1
Cheng, D; Dong, JH; Guo, YJ; Jin, F; Pang, R; Tao, JY; Ye, P; Zhang, SL; Zhao, L1
Forrest, D; Hagey, LR; Hofmann, AF; Ling, V; Liu, L; Sheps, JA; Wang, R1
Gurung, V; Hague, W; Middleton, P; Milan, SJ; Thornton, JG1
Denk, H; Eggertsen, G; Eller, K; Fickert, P; Halilbasic, E; Jaeschke, H; Krones, E; Langner, C; Moustafa, T; Pollheimer, MJ; Rosenkranz, AR; Silbert, D; Stokman, G; Thueringer, A; Trauner, M; Wagner, CA; Wells, RG; Yang, M1
Czaja, AJ1
Chen, XQ; Deng, YN; Shan, QW; Tang, Q; Wang, LL; Yun, X1
Bulut, G; Calka, O; Dulger, AC; Ozkol, HU1
Buryova, H; Chalupsky, K; Gregor, M; Jirouskova, M; Kanchev, I; Sedlacek, R; Zbodakova, O1
Bolia, R; Goel, D; Poddar, U; Srivastava, A; Yachha, SK1
Boyer, JL; Cai, SY; Mennone, A; Soroka, CJ1
Abidi, S; Baillie, R; Blood, AB; Dueker, S; Gordi, T; Hopper, AO; Pegis, P; Power, GG; Vasquez, H; Vuong, le T1
Burdina, EG; Gurova, NIu; Manushkin, ON; Novozhenova, EV; Vasil'chenko, SA1
Chamulitrat, W; Pathil, A; Sellinger, M; Stremmel, W; Xu, W1
Anantharajah, A; Grigg, A; Lokan, J; Yeh, P1
Mahmoud, YI; Saad, RA1
Bell, C; Graves, A; Imseis, EM; Mangalat, N1
Adams, DH; Beuers, U; Dyson, JK; Hirschfield, GM; Jones, DE; Lindor, KD; Mann, DA1
Assis, DN; Boyer, JL; Ghonem, NS1
Basu, S; Bhattacharya, A1
Kang, YZ; Liu, YH; Shen, ZY; Sun, XY1
Anastaze Stelle, K; Cachat, F; Chehade, H; Perez, MH1
Gavrilova, NP; Radchenko, VG; Seliverstov, PV; Tatarova, NA1
Ali, SW; Hassan, MU; Khan, SH; Malik, D; Pakala, R; Pasupula, M; Rather, TA; Yadav, N1
Duduk, NI; Kravchuk, RI; Zimatkin, SM1
Mahmoud, YI1
Sadeghi, R1
Malik, D1
Agrawal, DK; Kovilam, O; Larson, SP1
Cecchi, N; Garzi, A; Mandato, C; Orso, G; Vajro, P; Veropalumbo, C1
Halilbasic, E; Kuntner, C; Langer, O; Mairinger, S; Müller, M; Römermann, K; Stieger, B; Trauner, M; Visentin, M; Wanek, T1
Ali, AH; Lindor, KD1
Fleischer, AB; Pongcharoen, P1
Mittal, A1
Alawad, AS; Levy, C1
Hassan, HM; Jiang, Z; Li, X; Liu, R; Sun, R; Yang, H; Yuan, Z; Zhang, L1
Biswal, N; Chandrasekaran, V; Jagadisan, B; Nair, VS1
Eller, K; Fickert, P; Frauscher, B; Grahammer, F; Huber, TB; Kirsch, AH; Krones, E; Marschall, HU; Pollheimer, MJ; Racedo, S; Rosenkranz, AR; Ståhlman, M; Trauner, M; Wagner, K; Wahlström, A1
Halilbasic, E; Steinacher, D; Trauner, M1
Azzaroli, F; Colecchia, A; Di Biase, AR; Festi, D; Lodato, F; Mazzella, G; Montagnani, M; Roda, A; Roda, E; Simoni, P1
Castaño, B; Gonzalez-Buitrago, JM; Jimenez, S; Marin, JJ; Perez, MJ; Serrano, MA1
Moreno Villares, JM1
Jorgensen, BR; Mackenzie, PI; Meech, R; Miners, JO; Rogers, A; Treloar, J1
Kotb, MA1
Bhatia, K; Grossmith, AK; Heazell, AE1
Ko, KS; Li, J; Li, TW; Lu, SC; Oh, P; Ramani, K; Xia, M; Yang, H1
Gotthardt, D; Klöters-Plachky, P; Kulaksiz, H; Rost, D; Rudolph, G; Stiehl, A1
Cubells, E; Garzón, L; Ledo, A; Sáenz, P; Vento, M1
Briley, A; Broughton Pipkin, F; Chambers, J; Chappell, L; Gurung, V; Thornton, J; Williamson, C1
Adam, R; Reinshagen, K; Trunk, M; Wessel, LM1
Bhattacharya, A; Das, A; Poddar, U; Rao, KL; Singh, K; Thapa, BR1
Liu, XD; Wang, GJ; Yang, J; Yin, XF; Zhang, XY1
Akoglu, B; Faust, D; Milovic, V; Ristic, G1
Giliberti, P; Iorio, R; Nicastro, E; Raimondi, F; Tufano, M; Vegnente, A1
Fábrega, E; Pons-Romero, F; Terán, A1
Alex, G; Clarnette, T; Rosenbaum, J1
Ko, K; Li, J; Li, TW; Lu, SC; Oh, P; Xia, M; Yang, H1
Alvaro, D; Attili, AF; Bragazzi, MC; Callea, F; Giubilo, F; Merli, M1
Aehlen, A; Ehmer, U; Erichsen, TJ; Kalthoff, S; Manns, MP; Strassburg, CP1
Paumgartner, G1
Gotthardt, D; Kloeters-Plachky, P; Kulaksiz, H; Rost, D; Rudolph, G; Stiehl, A1
Gershwin, ME; Heathcote, EJ; Hirschfield, GM1
Beuers, U; Denk, GU; Ferdinandusse, S; Fickert, P; Fuchsbichler, A; Hofmann, AF; Invernizzi, P; Kulik, W; Maitz, S; Rust, C; Trauner, M; Wimmer, R1
Eisendle, K; Graziadei, I; Höpfl, R; Müller, H; Ortner, E; Talasz, H; Vogel, W1
Cardella, F; Corsello, G; Liotta, A; Maggio, MC1
Ackermann, O; Bernard, O; Branchereau, S; Franchi-Abella, S; Gonzales, E; Jacquemin, E; Mourier, O1
Bozdag, S; Dilmen, U; Erdeve, O; Gokmen, T; Oguz, SS; Uras, N1
Chaabane, NB; Njim, L; Safer, L; Saffar, H; Zakhama, A1
Kherbèche, H1
Drolz, A; Fuhrmann, V; Trauner, M1
Basiglio, CL; Boaglio, AC; Crocenzi, FA; Roma, MG; Sánchez Pozzi, EJ; Toledo, FD1
Celen, S; Danisman, N; Deveer, R; Engin-Ustun, Y; Eryilmaz, OG; Mollamahmutoğlu, L; Oksuzoglu, A; Tonguç, E1
Dick, AA; Healey, P; Horslen, SP; Hsu, E; Javid, PJ; Malone, FR; Sunseri, M1
Casadio, C; Gaddoni, G; Giacomoni, P; Lanzanova, G; Maio, V; Patrizi, A; Savoia, F; Spadola, G; Tabanelli, M; Zago, S1
Chambers, J; Tuson, A1
Bastiaansen, BA; Beuers, U; Dilger, K; Hohenester, S; Rust, C; Schaap, FG; Winkler-Budenhofer, U1
McKiernan, P1
Beuers, U; Maillette de Buy Wenniger, LJ; Oude Elferink, RP1
Canbay, A; Fingas, CD; Herzer, K1
Carey, EJ; Lindor, KD1
Jacquemin, E1
Erlinger, S1
Choi, MK; Han, JM; Hwang, SY; Kim, HG; Lee, JS; Park, HJ; Son, CG; Son, SW; Wang, JH1
Denk, H; Durchschein, F; Fickert, P; Halilbasic, E; Krones, E; Moustafa, T; Pollheimer, MJ; Silbert, D; Thüringer, A; Trauner, M; Zollner, G1
Duggan, C; Raphael, BP1
Allgaier, HP; Bassler, D; Galandi, D; Schwarzer, G1
Emmanuel, J; Micheline, D; Serge, E1
Beuers, U; Paumgartner, G2
Wang, L; Xie, W; Yao, D1
Matsuzaki, Y1
Palmeira, CM; Rolo, AP; Wallace, KB1
Berkenbosch, JW; George, R; Stevens, A; Tobias, J; Turpin, J1
Bravo, A; Briz, O; Macias, RI; Marin, JJ; Meier, PJ; Pascual, MJ; Serrano, MA; St-Pierre, MV; Stieger, B; Vallejo, M1
Black, RE; Book, LS; Jackson, WD; Johnson, DG; Matlak, ME; Meyers, RL; O'Gorman, MA1
Benedetti, A; Macarri, G; Marucci, L1
Catania, VA; Crocenzi, FA; Luquita, MG; Mottino, AD; Pellegrino, JM; Rodríguez Garay, EA; Roma, MG; Sánchez Pozzi, EJ1
Karvonen, AL1
Herrmann, T; Meier, PJ; Rost, D; Sauer, P; Schmidts, HL; Stieger, B; Stiehl, A; Stremmel, W1
Geubel, AP; Rahier, J; Sempoux, C1
Hofmann, AF3
Il'chenko, AA; Vikhrova, TV1
Chambers, J; Eggington, E; Elias, E; Gallagher, R; Milkiewicz, P; Weaver, J1
Szalay, F1
Ertekin, V; Orbak, Z; Selimoğlu, MA1
Forget, PP; Heemskerk, J; Heineman, E; Sie, GH; Van den Neucker, AM; van Heurn, LW1
Binz, J; Dennis, S; Desai, B; Goodwin, B; Jones, SA; Kliewer, SA; Liu, Y; Luo, G; MacKenzie, KI; Mansfield, TA; Numerick, MJ1
Ribal'chenko, VK; Sinel'nik, OD; Sinel'nik, TB1
Borras, C; Carretero, J; Cutrin, J; Pallardó, FV; Pereda, J; Poli, G; Sastre, J; Serviddio, G; Vendemiale, G; Viña, J1
Agca, E; Akcay, A; Simsek, H1
Chang, MH; Chen, CY; Chen, HL; Chou, HC; Hsieh, WS; Tsao, PN1
Hernandez, B; Jimenez, S; Macias, RI; Marin, JJ; Monte, MJ; Serrano, MA1
Blum, HE; Kreisel, W; Opitz, OG; Thimme, R1
El-Rifai, N; Gottrand, F1
Chapman, RW; Mitchell, SA2
Fickert, P; Trauner, M; Wagner, M; Zollner, G1
Chapman, RW; Cullen, SN1
Catania, VA; Crocenzi, FA; D'Andrea, V; Luquita, MG; Mottino, AD; Ochoa, JE; Pellegrino, JM; Sánchez Pozzi, EJ1
Duran, C; Gonzalez-Buitrago, JM; Macias, RI; Marin, JJ; Monte, MJ; Perez, MJ1
Copaci, I; Iliescu, L; Micu, L; Voiculescu, M1
Macias, RI; Marin, JJ; Perez, MJ1
Abulaimoun, B; Al-Hathlol, K; Al-Madani, A; Al-Saif, S; Al-Tawil, K; El-Demerdash, A1
Alpini, G; Benedetti, A; Fava, G; Francis, H; Glaser, S; Mancino, MG; Marzioni, M; Reichenbach, R; Summers, R; Ueno, Y; Venter, J1
Cheng, F; Diac, M; Girling, J; Goodman, J; Kenyon, A; Nelson-Piercy, C; Shennan, A; Tribe, RM; Williamson, C1
Asciutti, S; Baldoni, M; Camaioni, E; Castellani, D; Clementi, M; Clerici, C; Fiorucci, S; Giuliano, V; Mazzocchi, A; Morelli, A; Morelli, O; Nardi, E; O'Connell, NC; Orlandi, S; Pellicciari, R; Renga, B; Sabatino, G; Sadeghpour, B; Setchell, KD1
Beuers, U2
Jimenez, S; Macias, RI; Marin, JJ; Monte, MJ; Serrano, MA1
Beuers, U; Pusl, T1
Bruzzese, E; Colombo, C; De Marco, G; Di Caro, S; Guarino, A; Mambretti, D; Simoni, P; Sordino, D; Tramontano, A1
Fickert, P; Geier, A; Trauner, M1
O'Leary, JG; Pratt, DS1
Georgadakis, G; Gerovasilis, F; Karamouti, M1
Barbu, V; Beaussier, M; Callard, P; Fouassier, L; Housset, C; Lasnier, E; Lienhart, A; Mergey, M; Rey, C; Schiffer, E; Scoazec, JY; Stieger, B; Wendum, D1
Allard, JP; Raman, M1
Fauler, G; Gurakuqi, G; März, W; Putz-Bankuti, C; Scharnagl, H; Stadlbauer, V; Stauber, RE; Stojakovic, T; Trauner, M; Wagner, M1
Duarte-Rojo, A; Martínez-Benítez, B; Sánchez-Osorio, M; Torre, A; Uribe, M1
Btaiche, IF; San Luis, VA1
Gabe, SM; Lloyd, DA1
Dunn, JM; McNair, A1
Arslanoglu, S; Boehm, G; Moro, GE; Tauschel, HD1
Shan, RB; Zhu, MZ1
Itokazu, K; Sano, N; Yamanaka, M; Yokote, M1
Kanai, S; Kitani, K1
Han-Markey, T; Schumacher, RE; Teitelbaum, DH1
Accatino, L; Arrese, M; Koenig, C; Pizarro, M; Solís, N1
da Silva, RC; Davies, MH; Elias, E; Jones, SR; Weaver, JB1
Poupon, R; Poupon, RE2
Bendayan, M; Lambert, M; Levy, E; Paradis, K; Thibault, L1
Bonnefis, MT; Calmus, Y; Chereau, C; Podevin, P; Poupon, R; Veyrunes, C1
Piotrowicz, A; Polkey, M; Wilkinson, M1
Cruz, C; Estanes, A; Pedraza-Chaverrí, J; Poo, JL; Uribe, M1
Cagnoni, C; Carrara, GC; Castelli, A; Concesi, C; Crippa, G; Girometta, S; Pancotti, D; Pierfranceschi, MG; Sverzellati, E; Tacchini, G1
Finnie, I; Gilmore, I; Lombard, MJ; Rhodes, JM; Sutton, R1
Stiehl, A3
Akiyama, K; Aoshima, M; Hasegawa, T; Hotta, S; Kashiwaya, T; Katou, T; Kimura, A; Makino, I; Nakamura, K1
Besson, I; de Lédinghen, V; Fabre, M; Levillain, P; Morichau-Beauchant, M; Palazzo, L; Silvain, C1
Barrioz, T; Beauchant, M; Besson, I; de Ledinghen, V; Ingrand, P; Silvain, C1
Wilcox, MH1
Beau, P; Beauchant, M; Ingrand, P; Labat-Labourdette, J1
van Berge-Henegouwen, GP; Van de Meeberg, PC; van Erpecum, KJ1
Bianchi, L; Reichen, J1
Luketic, VA; Sanyal, AJ1
al-Quaiz, MN; O'Grady, JG; Tredger, JM; Williams, R1
van Berge Henegouwen, GP; van de Meeberg, PC; van Erpecum, KJ1
Dumont, M; Erlinger, S; Jacquemin, E; Mallet, A1
Bailey, RJ; Blendis, LM; Cauch-Dudek, K; Ghent, CN; Heathcote, EJ; Michieletti, P; Minuk, GY; Pappas, SC; Scully, LJ; Walker, V1
Bertault-Perès, P; Durand, A; Mesdjian, E; Montet, JC; Queneau, PE1
Reichen, J1
Kanai, S; Kitani, K; Ohta, M; Tsukahara, K1
Araki, T; Ishizaki, K; Kinbara, S; Miyazawa, N; Takeuchi, Y1
Accatino, L; Arrese, M1
Khandelwal, M; Malet, PF1
Faccioli, AM; Frezza, EE; Galligioni, A; Gerunda, GE; Giacomini, A; Neri, D; Plebani, M; Tiribelli, C1
Minagawa, K; Sano, N; Takikawa, H; Yamanaka, M1
Idei, T1
Sano, N; Takikawa, H; Yamanaka, M1
Bruining, HA; den Toom, R; Nijs, HG; Plaisier, PW; Terpstra, OT; van der Hul, RL1
Duraj, F; Ericzon, B; Rafael, E; Rudström, H; Wilczek, H1
Forsberg, L; Hägerstrand, I; Lyttkens, K; Prytz, H1
Lacaille, F1
Rudolph, G; Sauer, P; Stiehl, A; Theilmann, L1
Baumgartner, U; Farthmann, EH; Reinhardt, M; Ruf, G; Schölmerich, J; Sellinger, M1
Manns, MP; Schmidt, HH1
Parés, A; Rodés, J1
O'Brien, CB; Reddy, KR; Saul, SH; Shields, DS1
Barabino, A; Clayton, PT; Johnson, AW; Marazzi, MG; Mills, KA1
Bernard, B; Bouvier, E; Cabrol, A; Cadranel, JF; Dorent, R; Gandjbakhch, I; Gerhardt, M; Ghoussoub, JJ; Lunel, F; Myara, A; Opolon, P; Trivin, F1
Guarino, A; Iorio, R; Spagnuolo, MI; Vegnente, A1
Gerber, MA; Jacob, S; Mason, AL; Perrillo, RP1
Chan, G; Clandinin, MT; Duerksen, DR; Gramlich, L; Meddings, JB; Thomson, AB; Van Aerde, JE1
Di Leo, A; Diaferia, A; Iacovizzi, C; Loizzi, P; Nicastri, PL; Tartagni, M1
Bianchi, L; Dienes, HP; Gerken, G; Helmreich-Becker, I; Lohse, AW; Meyer zum Büschenfelde, KH; Protzer, U1
Capron, JP; Erlinger, S; Lévy, S1
Alvaro, D1
Boyer, J; Clerici, C; Gartung, C; Morelli, A; Rodrigues, CM; Setchell, KD; Solinas, A1
Camargo, CA; Clavien, PA; Fitz, JG; Harland, RC; Sharara, AI1
Chazouillères, O; Haniche, M; Jian, R; Marteau, P; Poupon, R1
Hori, Y; Ohyanagi, H1
Aoki, K; Kimura, A; Mahara, R; Suzuki, M; Tohma, M; Yamakawa, R1
Benz, C; Rudolph, G; Sauer, P; Stiehl, A; Stremmel, W; Theilmann, L; Walker, S1
Arslan, S; Güllú, IH; Kadayifci, A; Savas, MC1
Cağlar, M; Göğüş, S; Gürakan, F; Kale, G; Koçak, N; Yüce, A1
Teitelbaum, DH1
Bouscarel, B; Ceryak, S; Fromm, H; Gettys, TW; Le, M; Matsuzaki, Y; Shoda, J1
Bishop, WP; McCray, PB; Scher, H1
Araki, T; Hirabayashi, N; Ishizaki, K; Kasai, H; Kinbara, S; Sakakura, H1
Chan, CY; Chang, FY; Hsu, SH; Lee, SD; Lin, SH; Lu, CL1
Bährle, S; Dengler, TJ; Kübler, W; Stiehl, A; Szabó, G; Theilmann, L; Zimmermann, R1
Bouscarel, B; Fromm, H; Gettys, TW; Le, M; Matsuzaki, Y1
Aguilar, HI; Botla, R; Bronk, SF; Gores, GJ; Miyoshi, H1
Jonas, MM; Perez-Atayde, A; Srivastava, M1
Arenas, JI; Barrio, J; Castiella, A; Cosme, A; García-Bengoechea, M; Indart, A; Lobo, C; López, P1
Beuers, U; Boyer, JL; Paumgartner, G1
Javitt, NB1
Leuschner, U2
Bushma, MI; Karaedova, LM; Karpovich, VE; Khomich, TI; Konovalenko, OV; Lashak, LK; Legon'kova, LF; Zverinskiĭ, IV1
Batta, AK; Salen, G1
Benz, C; Klöters-Plachky, P; Rudolph, G; Sauer, P; Stiehl, A; Stremmel, W1
McDonald, JA1
Batts, KP; Gleich, GJ; Kephart, GM; Kita, H; Lindor, KD; Nakamura, A; Sato, S; Suzuki, K; Tarara, JE; Yamazaki, K1
Clark, TJ; Dwarakanath, L; Weaver, JB1
Kobayashi, S; Kumai, T; Nakaya, S; Nakura, H; Tanaka, M; Tateishi, T; Watanabe, M1
Amii, LA; Moss, RL1
Benedetti, P; de Lalla, F; Fabris, P; Mazzella, G; Nicolin, R; Pellizzer, G; Tositti, G; Zanetti, AR1
Descargues, G; Marpeau, L; Verspyck, E1
Rodrigues, CM; Steer, CJ2
Beauchant, M; De Lédinghen, V; Desaint, B; Greef, M; Grollier, G; Ingrand, P; Le Sidaner, A; Legoux, JL; Moesch, C; Person, B; Sautereau, D1
Bushma, MI; Legon'kova, LF; Vasil'ev, AV; Zverinskiĭ, IV1
Chazouillères, O; Poupon, R; Poupon, RE1
Kowdley, KV1
Anna, M; Antonio, C; Azzaroli, F; Bovicelli, L; Colecchia, A; Constance, M; Davide, F; Enrico, R; Festi, D; Francesco, A; Giovanni, N; Giuliana, S; Luciano, B; Mazzella, G; Miracolo, A; Mwangemi, C; Nicola, R; Nigro, G; Patrizia, S; Rizzo, N; Roda, E; Simonazzi, G; Simoni, P1
Marschall, HU; Matern, S; Purucker, E; Winograd, R1
Sanyal, A1
Abdullah, MA; Abomelha, AM; Al-Hasnan, Z; Okamoto, E1
Al-Ansari, N; Shneider, BL1
Burrows, E; Burrows, RF; Clavisi, O1
Bentley, RC; Dougherty, F; Hochman, JA; Treem, WR1
Btaiche, IF; Khalidi, N1
Attali, M; Borchardt, J; Mahlab, K; Malnick, SD; Sokolowski, N1
Azzaroli, F; Ferrara, F; Festi, D; Giovanelli, S; Liva, S; Mazzella, G; Nigro, G; Roda, E1
Gatzen, M; Pausch, J1
Linares Rodríguez, A1
Alpini, G; Angelico, M; Baiocchi, L; Francis, H; Glaser, S; Lesage, G; Marzioni, M; Phinizy, JL; Ueno, Y1
Gong, J; Han, B; Xu, M; Xue, L1
Dolfin, T; Raz, A; Regev, RH; Stolar, O1
Guma, C; Viola, L1
Chazalette, JP; Figarella, C; Galabert, C; Lecuire, A; Lengrand, D; Montet, JC; Sotta, C1
Hayakawa, T; Hoshino, M; Katagiri, K; Nakai, T; Ohiwa, T1
Fisher, LD; Fried, RH; McDonald, GB; Murakami, CS; Sullivan, KM; Willson, RA1
Braillon, A; Dumont, M; Erlinger, S; Feldmann, G; Gaudin, C; Lebrec, D; Poo, JL1
Duane, WC; Eckfeldt, JH; Furne, J; Hillstrom, J; Levitt, MD1
Hayashi, H; Higuchi, T; Hishida, N; Isomura, T; Takeshima, H1
Aldini, R; Bazzoli, F; Festi, D; Mazzella, G; Parini, P; Roda, E1
Egestad, B; Marschall, HU; Matern, H; Matern, S; Sjövall, J; Wietholtz, H1
Lehnert, W; Marschall, HU; Matern, H; Matern, S; Schill, A; Schumacher, B; Sjövall, J1
Calmus, Y; Poupon, R1
Mathisen, O; Omland, E1
Burnes, J; Lindor, KD1
de Caestecker, JS; Jazrawi, RP; Northfield, TC; Petroni, ML1
Beuers, U; Fischer, S; Paumgartner, G; Spengler, U1
Chazalette, JP; Dimier, JL; Galabert, C; Lengrand, D; Montet, JC1
Montet, JC1
Heuman, DM; Hylemon, PB; McCall, J; Mills, AS; Pandak, WM; Vlahcevic, ZR1
Borum, M; Fromm, H; Malet, PF1
Riely, CA1
Gams, E; Kallinowski, B; Kommerell, B; Stiehl, A; Theilmann, L; Zimmermann, R1
Kaplan, MM1
Berenson, MM; Bjorkman, DJ; Gunther, C; Samowitz, WS1
Bohdan, PM; Heuman, DM; Hylemon, PB; Sirica, AE; Vlahcevic, ZR1
Cotting, J; Lentze, MJ; Reichen, J1
Kurtz, W; Leuschner, U1
Bailey, ME; Pain, JA1
Hayakawa, T; Higashi, K; Hoshino, M; Ito, K; Katagiri, K; Miyaji, M; Takeuchi, T; Tsukada, K; Yamamoto, T1
Blenkharn, JI; Blumgart, LH; Cohen, J; Matkin, J; McConnell, JS; Moore, RH; Thompson, JN1
Barr, J; Blenkharn, JI; Blumgart, LH; Cohen, J; McConnell, JS; Thompson, JN1
Luciani, A; Massari, M; Montanari, P; Nora, A; Zandomeneghi, R1
Hayakawa, T; Higashi, K; Hoshino, M; Inaguma, H; Ito, M; Katagiri, K; Miyaji, M; Takeuchi, T; Tohyama, K; Tsunoka, S1

Reviews

118 review(s) available for ursodeoxycholic acid and Bile Duct Obstruction

ArticleYear
Macrophages in cholangiopathies.
    Current opinion in gastroenterology, 2022, 03-01, Volume: 38, Issue:2

    Topics: Animals; Bile Acids and Salts; Cholangitis, Sclerosing; Cholestasis; Humans; Inflammation; Macrophages; Mice; Ursodeoxycholic Acid

2022
Mechanisms and molecules: What are the treatment targets for primary biliary cholangitis?
    Hepatology (Baltimore, Md.), 2022, Volume: 76, Issue:2

    Topics: Cholagogues and Choleretics; Cholangitis; Cholestasis; Fibrosis; Humans; Inflammation; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

2022
Pretransplant Evaluation and Liver Transplantation Outcome in PBC Patients.
    Canadian journal of gastroenterology & hepatology, 2022, Volume: 2022

    Topics: Autoimmune Diseases; Cholagogues and Choleretics; Cholestasis; End Stage Liver Disease; Humans; Liver Cirrhosis, Biliary; Liver Transplantation; Ursodeoxycholic Acid

2022
Primary Biliary Cholangitis in Males: Pathogenesis, Clinical Presentation, and Prognosis.
    Clinics in liver disease, 2022, Volume: 26, Issue:4

    Topics: Cholangitis; Cholestasis; Female; Humans; Liver Cirrhosis, Biliary; Liver Diseases; Male; Prognosis; Ursodeoxycholic Acid

2022
Primary biliary cholangitis as a roadmap for the development of novel treatments for cholestatic liver diseases
    Journal of hepatology, 2023, Volume: 78, Issue:2

    Topics: Cholestasis; Humans; Liver Cirrhosis, Biliary; Membrane Transport Proteins; Receptors, Cytoplasmic and Nuclear; Ursodeoxycholic Acid

2023
Secondary bile acids and the biliary epithelia: The good and the bad.
    World journal of gastroenterology, 2023, Jan-14, Volume: 29, Issue:2

    Topics: Bile Acids and Salts; Biliary Tract; Cholestasis; Humans; Liver; Ursodeoxycholic Acid

2023
Efficacy and safety of ursodeoxycholic acid in children with cholestasis: A systematic review and meta-analysis.
    PloS one, 2023, Volume: 18, Issue:1

    Topics: Alanine Transaminase; Bile Acids and Salts; Bilirubin; Child; Cholestasis; Humans; Ursodeoxycholic Acid

2023
New Treatment Paradigms in Primary Biliary Cholangitis.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2023, Volume: 21, Issue:8

    Topics: Cholangitis; Cholestasis; Female; Humans; Liver Cirrhosis, Biliary; Male; Peroxisome Proliferator-Activated Receptors; Pruritus; Quality of Life; Ursodeoxycholic Acid

2023
[Diagnosis and Treatment of Primary Biliary Cholangitis].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2023, 02-25, Volume: 81, Issue:2

    Topics: Cholagogues and Choleretics; Cholangitis; Cholestasis; Female; Humans; Liver Cirrhosis, Biliary; Middle Aged; Ursodeoxycholic Acid

2023
Role of autoantibodies in the clinical management of primary biliary cholangitis.
    World journal of gastroenterology, 2023, Mar-28, Volume: 29, Issue:12

    Topics: Antibodies, Antinuclear; Autoantibodies; Cholangitis; Cholestasis; Humans; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

2023
Mechanism-based target therapy in primary biliary cholangitis: opportunities before liver cirrhosis?
    Frontiers in immunology, 2023, Volume: 14

    Topics: Animals; Cholangitis; Cholestasis; Fibrosis; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

2023
Drug Therapies for Chronic Cholestatic Liver Diseases.
    Annual review of pharmacology and toxicology, 2020, 01-06, Volume: 60

    Topics: Animals; Cholagogues and Choleretics; Cholangitis, Sclerosing; Cholestasis; Chronic Disease; Disease Progression; Humans; Liver Cirrhosis, Biliary; Receptors, Cytoplasmic and Nuclear; Ursodeoxycholic Acid

2020
Prolonged cholestasis following endoscopic retrograde cholangiopancreatography, a rare complication of contrast agent induced liver injury: A case report and literature review.
    Medicine, 2020, Volume: 99, Issue:3

    Topics: Aged; Cholagogues and Choleretics; Cholangiopancreatography, Endoscopic Retrograde; Cholestasis; Cholestyramine Resin; Contrast Media; Drug Therapy, Combination; Humans; Male; Ursodeoxycholic Acid

2020
Definition and Management of Patients With Primary Biliary Cholangitis and an Incomplete Response to Therapy.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2021, Volume: 19, Issue:11

    Topics: Bilirubin; Cholagogues and Choleretics; Cholestasis; Humans; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

2021
Pharmacological interventions for treating intrahepatic cholestasis of pregnancy.
    The Cochrane database of systematic reviews, 2020, 07-27, Volume: 7

    Topics: Charcoal; Cholagogues and Choleretics; Cholestasis; Cholestyramine Resin; Dexamethasone; Drugs, Chinese Herbal; Female; Fetal Distress; Galactans; Glucocorticoids; Humans; Mannans; Plant Gums; Pregnancy; Pregnancy Complications; Pruritus; Randomized Controlled Trials as Topic; S-Adenosylmethionine; Stillbirth; Ursodeoxycholic Acid

2020
Primary biliary cholangitis management: controversies, perspectives and daily practice implications from an expert panel.
    Liver international : official journal of the International Association for the Study of the Liver, 2020, Volume: 40, Issue:11

    Topics: Bile Acids and Salts; Cholestasis; Humans; Liver Cirrhosis, Biliary; Receptors, Cytoplasmic and Nuclear; Ursodeoxycholic Acid

2020
Current understanding of primary biliary cholangitis.
    Clinical and molecular hepatology, 2021, Volume: 27, Issue:1

    Topics: Carcinoma, Hepatocellular; Cholestasis; Humans; Liver Cirrhosis, Biliary; Liver Neoplasms; Ursodeoxycholic Acid

2021
Efficacy and safety of obeticholic acid in liver disease-A systematic review and meta-analysis.
    Clinics and research in hepatology and gastroenterology, 2021, Volume: 45, Issue:3

    Topics: Chenodeoxycholic Acid; Cholestasis; Humans; Liver Cirrhosis, Biliary; Non-alcoholic Fatty Liver Disease; Pharmaceutical Preparations; Ursodeoxycholic Acid

2021
[Physiopathology and management of cholestatic pruritus in children].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2017, Volume: 24, Issue:7

    Topics: Anion Exchange Resins; Biliary Tract Surgical Procedures; Child; Cholagogues and Choleretics; Cholestasis; Cholestyramine Resin; Chronic Disease; Cytochrome P-450 CYP3A Inducers; Humans; Liver Transplantation; Narcotic Antagonists; Pruritus; Rifampin; Selective Serotonin Reuptake Inhibitors; Sertraline; Sorption Detoxification; Ursodeoxycholic Acid

2017
[Chronic cholestatic liver diseases : Differential diagnosis, pathogenesis and current treatment in adults].
    Der Internist, 2017, Volume: 58, Issue:8

    Topics: Adult; Bezafibrate; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholestasis; Diagnosis, Differential; Humans; Liver Diseases; Ursodeoxycholic Acid

2017
Cholemic nephropathy - Historical notes and novel perspectives.
    Biochimica et biophysica acta. Molecular basis of disease, 2018, Volume: 1864, Issue:4 Pt B

    Topics: Acute Kidney Injury; Animals; Bile Acids and Salts; Bile Ducts; Bilirubin; Cholagogues and Choleretics; Cholestasis; Disease Models, Animal; Epithelial Cells; Hepatocytes; Humans; Jaundice, Obstructive; Kidney Tubules; Liver; Renal Elimination; Ursodeoxycholic Acid

2018
New therapies target the toxic consequences of cholestatic liver disease.
    Expert review of gastroenterology & hepatology, 2018, Volume: 12, Issue:3

    Topics: Bile Acids and Salts; Cholagogues and Choleretics; Cholangitis; Cholestasis; Chronic Disease; Humans; Organic Anion Transporters, Sodium-Dependent; Peroxisome Proliferator-Activated Receptors; Receptors, Cytoplasmic and Nuclear; Receptors, G-Protein-Coupled; Symporters; Ursodeoxycholic Acid

2018
Novel and emerging therapies for cholestatic liver diseases.
    Liver international : official journal of the International Association for the Study of the Liver, 2018, Volume: 38, Issue:9

    Topics: Bile Acids and Salts; Budesonide; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholangitis, Sclerosing; Cholestasis; Drug Therapy, Combination; Elasticity Imaging Techniques; Humans; Immunosuppressive Agents; Liver; Liver Cirrhosis, Biliary; Receptors, Cytoplasmic and Nuclear; Ursodeoxycholic Acid

2018
Management of Chronic Hepatic Itch.
    Dermatologic clinics, 2018, Volume: 36, Issue:3

    Topics: Analgesics, Opioid; Anion Exchange Resins; Antipruritics; Bezafibrate; Carrier Proteins; Cholagogues and Choleretics; Cholestasis; Cholestyramine Resin; Chronic Disease; Cytochrome P-450 Enzyme Inducers; Drainage; Humans; Hypolipidemic Agents; Membrane Glycoproteins; Methylamines; Narcotic Antagonists; Prevalence; Pruritus; Rifampin; Thiazepines; Ursodeoxycholic Acid

2018
Risk stratification and treatment of primary biliary cholangitis.
    Revista espanola de enfermedades digestivas, 2019, Volume: 111, Issue:1

    Topics: Adult; Age Factors; Alkaline Phosphatase; Biomarkers; Budesonide; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholangitis; Cholestasis; Disease Progression; Fibric Acids; Glucocorticoids; Humans; Liver Cirrhosis; Liver Transplantation; Middle Aged; Risk Assessment; Risk Factors; Sex Factors; Treatment Failure; Ursodeoxycholic Acid

2019
[PRIMARY BILIARY CHOLANGITIS: THERAPEUTIC APPROACH IN THE MODERN ERA].
    Harefuah, 2018, Volume: 157, Issue:12

    Topics: Cholagogues and Choleretics; Cholangitis; Cholestasis; Female; Humans; Liver Cirrhosis, Biliary; Middle Aged; Quality of Life; Ursodeoxycholic Acid

2018
Primary Biliary Cholangitis and Primary Sclerosing Cholangitis.
    The American journal of gastroenterology, 2019, Volume: 114, Issue:10

    Topics: Adult; Biliary Tract; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholangitis, Sclerosing; Cholestasis; Clinical Trials as Topic; Disease Progression; Drug Therapy, Combination; End Stage Liver Disease; Humans; Immunologic Factors; Life Expectancy; Prevalence; Prognosis; Treatment Outcome; Ursodeoxycholic Acid

2019
UDCA, NorUDCA, and TUDCA in Liver Diseases: A Review of Their Mechanisms of Action and Clinical Applications.
    Handbook of experimental pharmacology, 2019, Volume: 256

    Topics: Bile Acids and Salts; Cholestasis; Humans; Liver; Liver Diseases; Taurochenodeoxycholic Acid; Ursodeoxycholic Acid

2019
Nuclear receptors as drug targets in cholestatic liver diseases.
    Clinics in liver disease, 2013, Volume: 17, Issue:2

    Topics: Animals; Bile Acids and Salts; Cholagogues and Choleretics; Cholestasis; Constitutive Androstane Receptor; Homeostasis; Humans; Ligands; Peroxisome Proliferator-Activated Receptors; Pregnane X Receptor; Receptors, Calcitriol; Receptors, Cytoplasmic and Nuclear; Receptors, Glucocorticoid; Receptors, Steroid; Signal Transduction; Ursodeoxycholic Acid

2013
Interventions for treating cholestasis in pregnancy.
    The Cochrane database of systematic reviews, 2013, Jun-24, Issue:6

    Topics: Charcoal; Cholagogues and Choleretics; Cholestasis; Cholestyramine Resin; Drugs, Chinese Herbal; Female; Galactans; Humans; Mannans; Plant Gums; Pregnancy; Pregnancy Complications; Pruritus; Randomized Controlled Trials as Topic; S-Adenosylmethionine; Ursodeoxycholic Acid

2013
Diagnosis and management of the overlap syndromes of autoimmune hepatitis.
    Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2013, Volume: 27, Issue:7

    Topics: Adult; Alkaline Phosphatase; Cholangitis, Sclerosing; Cholestasis; Hepatitis, Autoimmune; Humans; Immunosuppressive Agents; Liver Cirrhosis, Biliary; Syndrome; Treatment Outcome; Ursodeoxycholic Acid

2013
Novel therapeutic targets in primary biliary cirrhosis.
    Nature reviews. Gastroenterology & hepatology, 2015, Volume: 12, Issue:3

    Topics: Cholagogues and Choleretics; Cholestasis; Humans; Liver Cirrhosis, Biliary; Molecular Targeted Therapy; Ursodeoxycholic Acid

2015
Fibrates and cholestasis.
    Hepatology (Baltimore, Md.), 2015, Volume: 62, Issue:2

    Topics: Biomarkers; Cholestasis; Female; Fibric Acids; Follow-Up Studies; Humans; Liver Cirrhosis, Biliary; Male; PPAR alpha; Risk Assessment; Severity of Illness Index; Treatment Outcome; Ursodeoxycholic Acid

2015
Streptococcus pneumoniae-Associated Hemolytic and Uremic Syndrome With Cholestasis: A Case Report and Brief Literature Review.
    Clinical pediatrics, 2016, Volume: 55, Issue:2

    Topics: Anti-Bacterial Agents; Cephalosporins; Child, Preschool; Cholagogues and Choleretics; Cholestasis; Diagnosis, Differential; Female; Humans; Peritoneal Dialysis; Pneumonia, Pneumococcal; Syndrome; Uremia; Ursodeoxycholic Acid

2016
Immunological basis in the pathogenesis of intrahepatic cholestasis of pregnancy.
    Expert review of clinical immunology, 2016, Volume: 12, Issue:1

    Topics: Animals; Cholestasis; Female; Humans; Immunity; Liver; Pregnancy; Pregnancy Complications; Th1-Th2 Balance; Th2 Cells; Ursodeoxycholic Acid

2016
Pediatric parenteral nutrition-associated liver disease and cholestasis: Novel advances in pathomechanisms-based prevention and treatment.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2016, Volume: 48, Issue:3

    Topics: Child; Child, Preschool; Cholagogues and Choleretics; Cholestasis; Fat Emulsions, Intravenous; Fatty Acids, Omega-3; Fish Oils; Humans; Infant; Infant, Newborn; Liver Diseases; Parenteral Nutrition; Soybean Oil; Ursodeoxycholic Acid

2016
Obeticholic acid for the treatment of primary biliary cholangitis.
    Expert opinion on pharmacotherapy, 2016, Volume: 17, Issue:13

    Topics: Animals; Autoimmune Diseases; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholangitis; Cholestasis; End Stage Liver Disease; Genome-Wide Association Study; Humans; Liver Cirrhosis, Biliary; Randomized Controlled Trials as Topic; Ursodeoxycholic Acid

2016
Itch Management: Systemic Agents.
    Current problems in dermatology, 2016, Volume: 50

    Topics: Amines; Analgesics; Analgesics, Opioid; Anion Exchange Resins; Antidepressive Agents; Aprepitant; Cholagogues and Choleretics; Cholestasis; Cholestyramine Resin; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Histamine Antagonists; Humans; Morpholines; Narcotic Antagonists; Neurokinin-1 Receptor Antagonists; Paraneoplastic Syndromes; Peripheral Nervous System Diseases; Pregabalin; Pruritus; Receptors, Opioid, kappa; Receptors, Opioid, mu; Rifampin; Thalidomide; Uremia; Ursodeoxycholic Acid

2016
Cholestatic Itch Management.
    Current problems in dermatology, 2016, Volume: 50

    Topics: Anion Exchange Resins; Cholagogues and Choleretics; Cholestasis; Cholestyramine Resin; Humans; Lysophospholipids; Naltrexone; Narcotic Antagonists; Plasmapheresis; Pregnane X Receptor; Pruritus; Receptors, Steroid; Rifampin; Selective Serotonin Reuptake Inhibitors; Sertraline; Ultraviolet Therapy; Ursodeoxycholic Acid

2016
FXR Agonists: From Bench to Bedside, a Guide for Clinicians.
    Digestive diseases and sciences, 2016, Volume: 61, Issue:12

    Topics: Animals; Azepines; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholestasis; Drug Evaluation, Preclinical; Gastrointestinal Agents; Hepatitis, Autoimmune; Humans; Hypertension, Portal; Indoles; Isoxazoles; Liver Cirrhosis, Alcoholic; Liver Cirrhosis, Biliary; Liver Diseases; Metabolic Syndrome; Non-alcoholic Fatty Liver Disease; Receptors, Cytoplasmic and Nuclear; Ursodeoxycholic Acid

2016
Nor-Ursodeoxycholic Acid as a Novel Therapeutic Approach for Cholestatic and Metabolic Liver Diseases.
    Digestive diseases (Basel, Switzerland), 2017, Volume: 35, Issue:3

    Topics: Animals; Cholestasis; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Liver Diseases; Metabolic Diseases; Ursodeoxycholic Acid

2017
Clinical efficacy and effectiveness of ursodeoxycholic acid in cholestatic liver diseases.
    Current clinical pharmacology, 2007, Volume: 2, Issue:2

    Topics: Animals; Bile Acids and Salts; Biological Transport, Active; Child; Cholagogues and Choleretics; Cholestasis; Female; Humans; Liver Diseases; Pregnancy; Ursodeoxycholic Acid

2007
[Parenteral nutrition-associated liver disease].
    Nutricion hospitalaria, 2008, Volume: 23 Suppl 2

    Topics: Age Factors; Cholagogues and Choleretics; Cholestasis; Enteral Nutrition; Humans; Infant, Newborn; Infant, Premature; Liver Diseases; Parenteral Nutrition; Risk Factors; Short Bowel Syndrome; Time Factors; Ursodeoxycholic Acid

2008
The chronic liver disease in patients with short bowel syndrome: etiology and treatment.
    Minerva pediatrica, 2009, Volume: 61, Issue:3

    Topics: Anti-Bacterial Agents; Child; Cholagogues and Choleretics; Cholestasis; Drug Therapy, Combination; Enteral Nutrition; Evidence-Based Medicine; Humans; Infant, Newborn; Infant, Premature; Intestine, Small; Liver Diseases; Parenteral Nutrition; Parenteral Nutrition, Home; Practice Guidelines as Topic; Prognosis; Risk Factors; Sepsis; Short Bowel Syndrome; Treatment Outcome; Ursodeoxycholic Acid

2009
[Hepatobiliary transport of glutathione and its role in cholestasis].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2009, Volume: 44, Issue:4

    Topics: Animals; Biological Transport; Cholestasis; Estrogens; Glutathione; Humans; Jaundice, Chronic Idiopathic; Liver; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Mutation; Phalloidine; Ursodeoxycholic Acid

2009
[Pruritus associated with cholestasis].
    Gastroenterologia y hepatologia, 2010, Volume: 33, Issue:4

    Topics: Animals; Anion Exchange Resins; Cholestasis; Evidence-Based Medicine; Female; Gastrin-Releasing Peptide; Haplorhini; Humans; Male; Models, Neurological; Narcotic Antagonists; Neural Pathways; Opioid Peptides; Posterior Horn Cells; Pregnancy; Pregnancy Complications; Pruritus; Randomized Controlled Trials as Topic; Rifampin; Ursodeoxycholic Acid

2010
Biliary physiology and disease: reflections of a physician-scientist.
    Hepatology (Baltimore, Md.), 2010, Volume: 51, Issue:4

    Topics: Animals; Bile; Bile Acids and Salts; Cholestasis; Gallstones; Humans; Indocyanine Green; Liver; Recurrence; Ursodeoxycholic Acid

2010
Pathogenesis of cholestatic liver disease and therapeutic approaches.
    Gastroenterology, 2010, Volume: 139, Issue:5

    Topics: Animals; Apoptosis; Bile; Cholagogues and Choleretics; Cholestasis; Cytokines; Hepatocytes; Humans; Immunity, Cellular; Immunosuppressive Agents; Liver Cirrhosis, Biliary; Prognosis; Risk Factors; Ursodeoxycholic Acid

2010
Extracorporeal artificial liver support systems in the management of intractable cholestatic pruritus.
    Liver international : official journal of the International Association for the Study of the Liver, 2011, Volume: 31 Suppl 3

    Topics: Cholestasis; Cholestyramine Resin; Humans; Lysophospholipids; Opioid Peptides; Plasmapheresis; Pruritus; Renal Dialysis; Rifampin; Sertraline; Sorption Detoxification; Ursodeoxycholic Acid

2011
Ursodeoxycholic acid in cholestasis: linking action mechanisms to therapeutic applications.
    Clinical science (London, England : 1979), 2011, Volume: 121, Issue:12

    Topics: Animals; Apoptosis; Bile Acids and Salts; Bile Canaliculi; Cholagogues and Choleretics; Cholestasis; Humans; Immunologic Factors; Mitochondria, Liver; Proto-Oncogene Proteins c-bcl-2; Ursodeoxycholic Acid

2011
Scratching can reveal more than just an itch.
    The practising midwife, 2011, Volume: 14, Issue:9

    Topics: Bile Acids and Salts; Cholagogues and Choleretics; Cholestasis; Female; Humans; Liver Function Tests; Midwifery; Nursing Diagnosis; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Pruritus; Ursodeoxycholic Acid; Young Adult

2011
Molecular targets for the treatment of fibrosing cholangiopathies.
    Clinical pharmacology and therapeutics, 2012, Volume: 92, Issue:3

    Topics: Biliary Tract; Cholangitis, Sclerosing; Cholestasis; Hepatocytes; Humans; Immunosuppressive Agents; Receptors, Cytoplasmic and Nuclear; Ursodeoxycholic Acid

2012
Current pharmacotherapy for cholestatic liver disease.
    Expert opinion on pharmacotherapy, 2012, Volume: 13, Issue:17

    Topics: Cholangitis, Sclerosing; Cholestasis; Fibric Acids; Hepatitis, Autoimmune; Humans; Receptors, Cytoplasmic and Nuclear; Ursodeoxycholic Acid

2012
Progressive familial intrahepatic cholestasis.
    Clinics and research in hepatology and gastroenterology, 2012, Volume: 36 Suppl 1

    Topics: Adenosine Triphosphatases; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biomarkers; Cholagogues and Choleretics; Cholestasis; Cholestasis, Intrahepatic; Disease Progression; France; gamma-Glutamyltransferase; Genotype; Humans; Jaundice; Mutation; Prevalence; Prognosis; Pruritus; Treatment Outcome; Ursodeoxycholic Acid

2012
Ursodeoxycholic acid and/or antibiotics for prevention of biliary stent occlusion.
    The Cochrane database of systematic reviews, 2002, Issue:3

    Topics: Anti-Bacterial Agents; Cholagogues and Choleretics; Cholestasis; Drug Therapy, Combination; Equipment Failure; Humans; Randomized Controlled Trials as Topic; Stents; Ursodeoxycholic Acid

2002
Ursodeoxycholic acid in cholestatic liver disease: mechanisms of action and therapeutic use revisited.
    Hepatology (Baltimore, Md.), 2002, Volume: 36, Issue:3

    Topics: Cholagogues and Choleretics; Cholestasis; Humans; Liver Diseases; Ursodeoxycholic Acid

2002
High-dose steroids, ursodeoxycholic acid, and chronic intravenous antibiotics improve bile flow after Kasai procedure in infants with biliary atresia.
    Journal of pediatric surgery, 2003, Volume: 38, Issue:3

    Topics: Administration, Oral; Adrenal Cortex Hormones; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bile; Biliary Atresia; Chemotherapy, Adjuvant; Cholagogues and Choleretics; Cholestasis; Female; Humans; Infant; Infusions, Intravenous; Liver Transplantation; Male; Methylprednisolone Hemisuccinate; Portoenterostomy, Hepatic; Postoperative Complications; Prednisone; Retrospective Studies; Treatment Outcome; Ursodeoxycholic Acid

2003
[Cholestasis. Recent diagnostic and therapeutic acquisitions].
    Recenti progressi in medicina, 2003, Volume: 94, Issue:1

    Topics: Cholangiography; Cholangiopancreatography, Endoscopic Retrograde; Cholangitis, Sclerosing; Cholelithiasis; Cholestasis; Cholestasis, Intrahepatic; Clinical Trials as Topic; Endoscopy, Digestive System; Follow-Up Studies; Humans; Liver Cirrhosis, Biliary; Liver Transplantation; Magnetic Resonance Imaging; Meta-Analysis as Topic; Mutation; Risk Factors; Time Factors; Ursodeoxycholic Acid

2003
[Treatment of cholestatic liver diseases].
    Duodecim; laaketieteellinen aikakauskirja, 2003, Volume: 119, Issue:6

    Topics: Adrenal Cortex Hormones; Antimetabolites; Cholagogues and Choleretics; Cholangiopancreatography, Endoscopic Retrograde; Cholangitis, Sclerosing; Cholestasis; Colchicine; Humans; Liver Cirrhosis, Biliary; Liver Transplantation; Stents; Ursodeoxycholic Acid

2003
Bile duct disorders.
    Clinics in liver disease, 2003, Volume: 7, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Antimetabolites, Antineoplastic; Antiviral Agents; Bile Duct Diseases; Cholagogues and Choleretics; Cholestasis; Drug Therapy, Combination; Humans; Radiotherapy; Ursodeoxycholic Acid

2003
[The problem of biliary sludge].
    Klinicheskaia meditsina, 2003, Volume: 81, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Bile; Cholagogues and Choleretics; Cholelithiasis; Cholestasis; Gallbladder; Humans; Sphincter of Oddi; Ultrasonography; Ursodeoxycholic Acid

2003
[Treatment of primary biliary cirrhosis].
    Orvosi hetilap, 2003, Sep-07, Volume: 144, Issue:36

    Topics: Antioxidants; Cholagogues and Choleretics; Cholestasis; Cholestyramine Resin; Colchicine; Enzyme Inhibitors; Humans; Liver; Liver Cirrhosis, Biliary; Liver Transplantation; Methotrexate; Ursodeoxycholic Acid

2003
[Bile acids in the process of canalicular bile formation].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2003, Volume: 49, Issue:6

    Topics: Animals; Apoptosis; Bile; Bile Acids and Salts; Bile Canaliculi; Biological Transport, Active; Cholestasis; Gene Expression Regulation; Hepatocytes; Humans; Hydrophobic and Hydrophilic Interactions; Membrane Transport Proteins; Necrosis; Ursodeoxycholic Acid

2003
Mechanisms of action and therapeutic efficacy of ursodeoxycholic acid in cholestatic liver disease.
    Clinics in liver disease, 2004, Volume: 8, Issue:1

    Topics: Cholestasis; Enterohepatic Circulation; Humans; Liver Diseases; Treatment Outcome; Ursodeoxycholic Acid

2004
[Cholestatic liver diseases].
    Therapeutische Umschau. Revue therapeutique, 2004, Volume: 61, Issue:8

    Topics: Anti-Bacterial Agents; Antibodies, Antineutrophil Cytoplasmic; Anticholesteremic Agents; Antipruritics; Autoimmune Diseases; Bile Ducts; Cholagogues and Choleretics; Cholangiography; Cholangitis; Cholangitis, Sclerosing; Cholestasis; Cholestyramine Resin; Clinical Enzyme Tests; Diagnosis, Differential; Hepatitis, Autoimmune; Humans; Immunosuppression Therapy; Inflammatory Bowel Diseases; Liver Cirrhosis; Liver Cirrhosis, Biliary; Liver Transplantation; Naloxone; Naltrexone; Narcotic Antagonists; Ondansetron; Plasmapheresis; Ursodeoxycholic Acid

2004
[Role of ursodeoxycholic acid in pediatric cholestatic disease].
    Gastroenterologie clinique et biologique, 2004, Volume: 28, Issue:10 Pt 1

    Topics: Child; Cholagogues and Choleretics; Cholestasis; Humans; Ursodeoxycholic Acid

2004
The management of primary sclerosing cholangitis.
    Clinics in liver disease, 1998, Volume: 2, Issue:2

    Topics: Adrenal Cortex Hormones; Cholangitis, Sclerosing; Cholestasis; Humans; Immunosuppressive Agents; Methotrexate; Penicillamine; Ursodeoxycholic Acid

1998
Molecular regulation of hepatobiliary transport systems: clinical implications for understanding and treating cholestasis.
    Journal of clinical gastroenterology, 2005, Volume: 39, Issue:4 Suppl 2

    Topics: Animals; Bile; Bile Acids and Salts; Biliary Tract; Biological Transport, Active; Cholangitis, Sclerosing; Cholestasis; Cholestasis, Intrahepatic; Humans; Liver; Liver Cirrhosis, Biliary; Mice; Mutation; Receptors, Cytoplasmic and Nuclear; Ursodeoxycholic Acid

2005
Review article: current management of primary sclerosing cholangitis.
    Alimentary pharmacology & therapeutics, 2005, Apr-15, Volume: 21, Issue:8

    Topics: Cholagogues and Choleretics; Cholangitis, Sclerosing; Cholestasis; Combined Modality Therapy; Endoscopy, Digestive System; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Liver Cirrhosis; Liver Failure; Liver Transplantation; Stents; Ursodeoxycholic Acid

2005
New therapeutical indications of ursodeoxycholic acid.
    Romanian journal of gastroenterology, 2005, Volume: 14, Issue:3

    Topics: Bile Acids and Salts; Cholagogues and Choleretics; Cholangitis, Sclerosing; Cholestasis; Female; Hepatocytes; Humans; Liver Cirrhosis; Liver Cirrhosis, Biliary; Mitochondria, Liver; Oxidative Stress; Pregnancy; Pregnancy Complications; Ursodeoxycholic Acid

2005
Drug insight: Mechanisms and sites of action of ursodeoxycholic acid in cholestasis.
    Nature clinical practice. Gastroenterology & hepatology, 2006, Volume: 3, Issue:6

    Topics: Animals; Bile; Cholagogues and Choleretics; Cholestasis; Humans; Treatment Outcome; Ursodeoxycholic Acid

2006
Ursodeoxycholic acid treatment of vanishing bile duct syndromes.
    World journal of gastroenterology, 2006, Jun-14, Volume: 12, Issue:22

    Topics: Apoptosis; Bile Acids and Salts; Bile Duct Diseases; Bile Ducts, Intrahepatic; Cholagogues and Choleretics; Cholestasis; Humans; Liver Cirrhosis; Liver Failure; Syndrome; Ursodeoxycholic Acid

2006
Mechanisms of disease: mechanisms and clinical implications of cholestasis in sepsis.
    Nature clinical practice. Gastroenterology & hepatology, 2006, Volume: 3, Issue:10

    Topics: Adrenal Cortex Hormones; Bacterial Infections; Bile; Bile Ducts; Cholestasis; Cytokines; Humans; Liver; Liver Diseases; Liver Transplantation; Nitric Oxide; Sepsis; Ursodeoxycholic Acid

2006
Cholestasis and cholestatic syndromes.
    Current opinion in gastroenterology, 2007, Volume: 23, Issue:3

    Topics: Animals; Bile Acids and Salts; Biological Transport; Cholangiopancreatography, Endoscopic Retrograde; Cholestasis; Humans; Prognosis; Syndrome; Ursodeoxycholic Acid

2007
Parenteral nutrition related hepato-biliary disease in adults.
    Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2007, Volume: 32, Issue:4

    Topics: Adult; Anti-Bacterial Agents; Biliary Tract Diseases; Cholestasis; Fatty Liver; Gallstones; Hepatitis; Humans; Intestines; Liver Diseases; Liver Transplantation; Parenteral Nutrition, Total; Ursodeoxycholic Acid

2007
Ursodiol in patients with parenteral nutrition-associated cholestasis.
    The Annals of pharmacotherapy, 2007, Volume: 41, Issue:11

    Topics: Animals; Cholagogues and Choleretics; Cholestasis; Humans; Parenteral Nutrition; Ursodeoxycholic Acid

2007
Managing liver dysfunction in parenteral nutrition.
    The Proceedings of the Nutrition Society, 2007, Volume: 66, Issue:4

    Topics: Anti-Bacterial Agents; Cholestasis; Enteral Nutrition; Humans; Liver Diseases; Parenteral Nutrition; Risk Factors; Sepsis; Ursodeoxycholic Acid

2007
[Pathogenesis and progress in treatment of neonatal total parenteral nutrition-associated cholestasis].
    Zhonghua er ke za zhi = Chinese journal of pediatrics, 2008, Volume: 46, Issue:1

    Topics: Cholestasis; Female; Humans; Liver Diseases; Male; Neonatology; Parenteral Nutrition, Total; S-Adenosylmethionine; Ursodeoxycholic Acid

2008
[Abnormal bile acids in obstructive jaundice].
    Nihon rinsho. Japanese journal of clinical medicine, 1984, Volume: 42, Issue:7

    Topics: Animals; Bile Acids and Salts; Cholestasis; Cholic Acid; Cholic Acids; Glycine; Humans; Rats; Taurine; Ursodeoxycholic Acid

1984
Ursodeoxycholic acid therapy of chronic cholestatic conditions in adults and children.
    Pharmacology & therapeutics, 1995, Volume: 66, Issue:1

    Topics: Adult; Bile Acids and Salts; Child; Cholestasis; Clinical Trials as Topic; Cystic Fibrosis; Female; Humans; Intestinal Absorption; Liver; Pregnancy; Pregnancy Complications; Ursodeoxycholic Acid

1995
Defective biliary secretion during total parenteral nutrition: probable mechanisms and possible solutions.
    Journal of pediatric gastroenterology and nutrition, 1995, Volume: 20, Issue:4

    Topics: Adult; Bile; Bile Acids and Salts; Biliary Tract; Child; Cholestasis; Fasting; Humans; Infant; Parenteral Nutrition, Total; Ursodeoxycholic Acid

1995
Pharmacology of ursodeoxycholic acid, an enterohepatic drug.
    Scandinavian journal of gastroenterology. Supplement, 1994, Volume: 204

    Topics: Bile Acids and Salts; Cholestasis; Humans; Liver Diseases; Ursodeoxycholic Acid

1994
Ursodeoxycholic acid in the treatment of primary sclerosing cholangitis.
    Annals of medicine, 1994, Volume: 26, Issue:5

    Topics: Cholangitis, Sclerosing; Cholestasis; Humans; Ursodeoxycholic Acid

1994
Therapy with ursodeoxycholic acid in cholestatic liver disease.
    Scandinavian journal of gastroenterology. Supplement, 1993, Volume: 200

    Topics: Cholangitis, Sclerosing; Cholestasis; Cholestasis, Intrahepatic; Cystic Fibrosis; Female; Humans; Liver Cirrhosis, Biliary; Liver Diseases; Liver Transplantation; Postoperative Care; Pregnancy; Pregnancy Complications; Recurrence; Ursodeoxycholic Acid

1993
The current status of ursodeoxycholate in the treatment of chronic cholestatic liver disease.
    The Gastroenterologist, 1994, Volume: 2, Issue:1

    Topics: Alagille Syndrome; Biliary Atresia; Cholangitis, Sclerosing; Cholestasis; Chronic Disease; Cystic Fibrosis; Graft vs Host Disease; Humans; Liver Cirrhosis, Biliary; Liver Diseases; Ursodeoxycholic Acid

1994
Rationale for therapy with ursodeoxycholic acid in patients with cholestatic liver disease.
    The Netherlands journal of medicine, 1993, Volume: 43, Issue:5-6

    Topics: Bile Acids and Salts; Cholestasis; Enterohepatic Circulation; Humans; Liver Cirrhosis, Biliary; Liver Diseases; Ursodeoxycholic Acid

1993
Pharmacologic treatment of cholestasis.
    Seminars in liver disease, 1993, Volume: 13, Issue:3

    Topics: Cholestasis; Cholestyramine Resin; Colestipol; Enzyme Induction; Humans; Pruritus; S-Adenosylmethionine; Ursodeoxycholic Acid

1993
[Ursodeoxycholic acid in the treatment of cholestatic liver diseases].
    Revista medica de Chile, 1993, Volume: 121, Issue:4

    Topics: Bile; Cholestasis; Humans; Liver; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

1993
Pruritus associated with cholestasis. A review of pathogenesis and management.
    Digestive diseases and sciences, 1994, Volume: 39, Issue:1

    Topics: Androgens; Antipruritics; Bile Acids and Salts; Cholestasis; Cholestyramine Resin; Female; Humans; Narcotic Antagonists; Plasmapheresis; Pregnancy; Pregnancy Complications; Propofol; Pruritus; Rifampin; Ultraviolet Therapy; Ursodeoxycholic Acid

1994
Intestinal absorption of bile acids: effect of ursodeoxycholic acid treatment.
    The Italian journal of gastroenterology, 1995, Volume: 27, Issue:4

    Topics: Administration, Oral; Bile Acids and Salts; Binding, Competitive; Cholestasis; Humans; Ileum; Intestinal Absorption; Solubility; Ursodeoxycholic Acid

1995
[Bile acids and their therapeutic use in children].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 1995, Volume: 2, Issue:12

    Topics: Adult; Animals; Bile Acids and Salts; Cell Membrane; Child; Cholagogues and Choleretics; Cholestasis; Chronic Disease; Cystic Fibrosis; Humans; Immunosuppressive Agents; Ursodeoxycholic Acid

1995
[Ursodeoxycholic acid: an alternative in the treatment of chronic cholestasis].
    Gastroenterologia y hepatologia, 1996, Volume: 19, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Bone Marrow Transplantation; Cholangitis, Sclerosing; Cholestasis; Cholestasis, Intrahepatic; Chronic Disease; Female; Graft vs Host Disease; Hepatitis; Hepatitis, Alcoholic; Humans; Liver Cirrhosis; Liver Cirrhosis, Alcoholic; Liver Transplantation; Male; Pregnancy; Pregnancy Complications; Time Factors; Ursodeoxycholic Acid

1996
Drug-induced vanishing bile duct syndrome: response to ursodiol.
    The American journal of gastroenterology, 1996, Volume: 91, Issue:7

    Topics: Antipsychotic Agents; Bile Duct Diseases; Cholagogues and Choleretics; Cholestasis; Chronic Disease; Female; Humans; Liver Function Tests; Middle Aged; Prochlorperazine; Syndrome; Ursodeoxycholic Acid

1996
[Mechanism of action of ursodeoxycholic acid in cholestatic liver diseases].
    Gastroenterologie clinique et biologique, 1996, Volume: 20, Issue:6-7

    Topics: Cholagogues and Choleretics; Cholestasis; Humans; Ursodeoxycholic Acid

1996
Pharmacological treatment of cholestasis.
    Methods and findings in experimental and clinical pharmacology, 1996, Volume: 18 Suppl B

    Topics: Animals; Cholagogues and Choleretics; Cholestasis; Clinical Trials as Topic; Humans; Rats; S-Adenosylmethionine; Ursodeoxycholic Acid

1996
Review article: the management of primary sclerosing cholangitis.
    Alimentary pharmacology & therapeutics, 1997, Volume: 11, Issue:1

    Topics: Chelating Agents; Cholangitis, Sclerosing; Cholestasis; Gastrointestinal Agents; Humans; Immunosuppressive Agents; Liver Failure; Liver Transplantation; Prognosis; Ursodeoxycholic Acid

1997
Parenteral nutrition-associated cholestasis.
    Current opinion in pediatrics, 1997, Volume: 9, Issue:3

    Topics: Bacterial Translocation; Cholagogues and Choleretics; Cholecystokinin; Cholestasis; Humans; Infant, Newborn; Parenteral Nutrition, Total; Ursodeoxycholic Acid

1997
Ursodeoxycholic acid in cholestasis: potential mechanisms of action and therapeutic applications.
    Hepatology (Baltimore, Md.), 1998, Volume: 28, Issue:6

    Topics: Bile Acids and Salts; Chemical Phenomena; Chemistry, Physical; Cholestasis; Humans; Liver; Ursodeoxycholic Acid

1998
Bile acid abnormalities in cholestatic liver diseases.
    Gastroenterology clinics of North America, 1999, Volume: 28, Issue:1

    Topics: Bile Acids and Salts; Cholagogues and Choleretics; Cholestasis; Humans; Liver Function Tests; Molecular Structure; Ursodeoxycholic Acid

1999
Cholestasis of pregnancy.
    Journal of gastroenterology and hepatology, 1999, Volume: 14, Issue:6

    Topics: Antipruritics; Cholestasis; Cholestyramine Resin; Dexamethasone; Female; Fetal Distress; Gastrointestinal Agents; Glucocorticoids; Humans; Pregnancy; Pregnancy Complications; Prevalence; Pruritus; S-Adenosylmethionine; Ursodeoxycholic Acid

1999
Pruritus in pregnancy and obstetric cholestasis.
    Hospital medicine (London, England : 1998), 1999, Volume: 60, Issue:4

    Topics: Cholagogues and Choleretics; Cholestasis; Female; Fetal Death; Humans; Infant Mortality; Infant, Newborn; Liver Function Tests; Pregnancy; Pregnancy Complications; Pruritus; Ursodeoxycholic Acid

1999
New approaches to understanding the etiology and treatment of total parenteral nutrition-associated cholestasis.
    Seminars in pediatric surgery, 1999, Volume: 8, Issue:3

    Topics: Animals; Cholecystokinin; Cholestasis; Humans; Methionine; Parenteral Nutrition, Total; Phytosterols; S-Adenosylmethionine; Ursodeoxycholic Acid

1999
Mitochondrial membrane perturbations in cholestasis.
    Journal of hepatology, 2000, Volume: 32, Issue:1

    Topics: Animals; Apoptosis; Cholestasis; Humans; Intracellular Membranes; Mitochondria, Liver; Ursodeoxycholic Acid

2000
Chronic cholestatic diseases.
    Journal of hepatology, 2000, Volume: 32, Issue:1 Suppl

    Topics: Adult; Anti-Inflammatory Agents; Child, Preschool; Cholagogues and Choleretics; Cholestasis; Chronic Disease; Humans; Immunosuppressive Agents; Liver Transplantation; Ursodeoxycholic Acid

2000
Ursodeoxycholic acid therapy in hepatobiliary disease.
    The American journal of medicine, 2000, Apr-15, Volume: 108, Issue:6

    Topics: Biliary Tract Diseases; Bone Marrow Transplantation; Cholagogues and Choleretics; Cholangitis, Sclerosing; Cholestasis; Chronic Disease; Cystic Fibrosis; Female; Graft Rejection; Graft vs Host Disease; Humans; Liver Cirrhosis, Biliary; Liver Diseases; Liver Transplantation; Parenteral Nutrition, Total; Pregnancy; Pregnancy Complications; Ursodeoxycholic Acid

2000
Treatment of cholestasis and cholestatic disorders.
    Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2001, Volume: 20 Suppl 1

    Topics: Cholagogues and Choleretics; Cholestasis; Chronic Disease; Humans; Ursodeoxycholic Acid

2001
Interventions for treating cholestasis in pregnancy.
    The Cochrane database of systematic reviews, 2001, Issue:4

    Topics: Charcoal; Cholestasis; Female; Galactans; Humans; Mannans; Plant Gums; Pregnancy; Pregnancy Complications; Randomized Controlled Trials as Topic; S-Adenosylmethionine; Ursodeoxycholic Acid

2001
The therapeutic effects of ursodeoxycholic acid as an anti-apoptotic agent.
    Expert opinion on investigational drugs, 2001, Volume: 10, Issue:7

    Topics: Animals; Apoptosis; Bile Acids and Salts; Cholestasis; Humans; Mitochondria; Neurodegenerative Diseases; Neuroprotective Agents; Ursodeoxycholic Acid

2001
Parenteral nutrition-associated liver complications in children.
    Pharmacotherapy, 2002, Volume: 22, Issue:2

    Topics: Alkaline Phosphatase; Anti-Bacterial Agents; Bilirubin; Carnitine; Child; Cholestasis; gamma-Glutamyltransferase; Humans; Liver; Liver Diseases; Parenteral Nutrition; Sepsis; Sincalide; Taurine; Ursodeoxycholic Acid

2002
[Treatment of cholestatic liver diseases].
    Medizinische Klinik (Munich, Germany : 1983), 2002, Mar-15, Volume: 97, Issue:3

    Topics: Adult; Age Factors; Anti-Inflammatory Agents; Azathioprine; Bile; Child; Cholagogues and Choleretics; Cholangitis, Sclerosing; Cholestasis; Cholestasis, Intrahepatic; Chronic Disease; Controlled Clinical Trials as Topic; Cystic Fibrosis; Drug Therapy, Combination; Female; Hepatitis; Humans; Immunosuppressive Agents; Infant, Newborn; Liver Cirrhosis, Biliary; Male; Prednisolone; Pregnancy; Pregnancy Complications; Time Factors; Ursodeoxycholic Acid

2002
[Medical treatment of chronic cholestasis: ursodeoxycholic acid].
    Gastroenterologia y hepatologia, 2000, Volume: 23 Suppl 1

    Topics: Adjuvants, Immunologic; Bile Acids and Salts; Cholagogues and Choleretics; Cholangitis, Sclerosing; Cholestasis; Chronic Disease; Humans; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

2000
Ursodeoxycholic acid for the treatment of cholestatic diseases.
    Progress in liver diseases, 1992, Volume: 10

    Topics: Adult; Child; Cholangitis, Sclerosing; Cholestasis; Cystic Fibrosis; Female; Humans; Liver Cirrhosis, Alcoholic; Liver Cirrhosis, Biliary; Liver Transplantation; Pregnancy; Pregnancy Complications; Ursodeoxycholic Acid

1992
[Pathophysiology of cholestasis: correlation between bile acid metabolism and liver damage].
    Zeitschrift fur Gastroenterologie, 1992, Volume: 30 Suppl 1

    Topics: Animals; Bile Acids and Salts; Cholestasis; Humans; Liver; Liver Cirrhosis, Biliary; Liver Cirrhosis, Experimental; Ursodeoxycholic Acid

1992
Advances in the therapy of cholestatic liver disease.
    Hepato-gastroenterology, 1992, Volume: 39 Suppl 1

    Topics: Cholestasis; Colchicine; Humans; Immunosuppressive Agents; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

1992
Ursodeoxycholic acid (UDCA) in the treatment of chronic cholestatic diseases.
    Biochimie, 1991, Volume: 73, Issue:10

    Topics: Animals; Cholestasis; Chronic Disease; Histocompatibility Antigens Class I; Humans; In Vitro Techniques; Liver Cirrhosis, Biliary; Major Histocompatibility Complex; Ursodeoxycholic Acid

1991
Ursodeoxycholic acid in chronic liver disease.
    Gut, 1991, Volume: 32, Issue:9

    Topics: Animals; Cholestasis; Chronic Disease; Hepatitis; Humans; Liver Cirrhosis, Biliary; Liver Diseases; Ursodeoxycholic Acid

1991
[Ursodeoxycholic acid. Physical properties and hepatoprotective activity].
    Pathologie-biologie, 1991, Volume: 39, Issue:6

    Topics: Animals; Bile Acids and Salts; Chemical Phenomena; Chemistry, Physical; Cholestasis; Cystic Fibrosis; Humans; Rats; Ursodeoxycholic Acid

1991
Medical approaches to primary sclerosing cholangitis.
    Seminars in liver disease, 1991, Volume: 11, Issue:1

    Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antipruritics; Azathioprine; Cholangitis, Sclerosing; Cholestasis; Cholestyramine Resin; Humans; Mercaptopurine; Methotrexate; Penicillamine; Ursodeoxycholic Acid; Vitamins

1991

Trials

26 trial(s) available for ursodeoxycholic acid and Bile Duct Obstruction

ArticleYear
Effects of S-adenosyl-L-Methionine Combined with Ursodesoxycholic Acid on Serum Endotoxin, MMP-9 and IL-18 in Neonates with Cholestasis.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2021, Volume: 31, Issue:12

    Topics: Cholestasis; Cholestasis, Intrahepatic; Endotoxins; Female; Humans; Infant, Newborn; Interleukin-18; Matrix Metalloproteinase 9; Methionine; Pregnancy; Pregnancy Complications; S-Adenosylmethionine; Ursodeoxycholic Acid

2021
Ursodeoxycholic acid prevention on cholestasis associated with total parenteral nutrition in preterm infants: a randomized trial.
    World journal of pediatrics : WJP, 2022, Volume: 18, Issue:2

    Topics: Cholestasis; Humans; Infant; Infant, Newborn; Infant, Premature; Parenteral Nutrition, Total; Prospective Studies; Retrospective Studies; Ursodeoxycholic Acid

2022
norUrsodeoxycholic acid improves cholestasis in primary sclerosing cholangitis.
    Journal of hepatology, 2017, Volume: 67, Issue:3

    Topics: Adult; Alkaline Phosphatase; Cholangitis, Sclerosing; Cholestasis; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Ursodeoxycholic Acid

2017
Pharmacokinetic analysis of 14C-ursodiol in newborn infants using accelerator mass spectrometry.
    Journal of clinical pharmacology, 2014, Volume: 54, Issue:9

    Topics: Carbon Radioisotopes; Cholestasis; Female; Humans; Infant; Infant, Newborn; Male; Mass Spectrometry; Models, Biological; Radioactive Tracers; Ursodeoxycholic Acid

2014
[Approaches to the treatment of patients with climacteric disorders complicated with menopausal metabolic syndrome with cholestasis].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2014, Issue:8

    Topics: Body Mass Index; Cholagogues and Choleretics; Cholestasis; Drug Therapy, Combination; Estrogen Replacement Therapy; Female; Humans; Menopause; Metabolic Syndrome; Middle Aged; Treatment Outcome; Ultrasonography; Ursodeoxycholic Acid

2014
A controlled trial of erythromycin and UDCA in premature infants during parenteral nutrition in minimizing feeding intolerance and liver function abnormalities.
    Journal of perinatology : official journal of the California Perinatal Association, 2012, Volume: 32, Issue:2

    Topics: Administration, Oral; Child Development; Cholestasis; Double-Blind Method; Erythromycin; Feeding and Eating Disorders; Feeding Behavior; Female; Follow-Up Studies; Humans; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Intensive Care Units, Neonatal; Liver Diseases; Liver Function Tests; Male; Parenteral Nutrition; Prospective Studies; Risk Assessment; Ursodeoxycholic Acid; Weight Gain

2012
Effect of ursodeoxycholic acid on bile acid profiles and intestinal detoxification machinery in primary biliary cirrhosis and health.
    Journal of hepatology, 2012, Volume: 57, Issue:1

    Topics: Adult; Bile Acids and Salts; Biliary Tract; Carrier Proteins; Cholagogues and Choleretics; Cholestasis; Cytochrome P-450 CYP3A; Duodenum; Female; Gene Expression Profiling; Glycine; Humans; Inactivation, Metabolic; Intestinal Mucosa; Liver Cirrhosis, Biliary; Middle Aged; Taurine; Ursodeoxycholic Acid

2012
Dexamethasone in the treatment of obstetric cholestasis: a case series.
    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2006, Volume: 26, Issue:2

    Topics: Anti-Inflammatory Agents; Cholagogues and Choleretics; Cholestasis; Dexamethasone; Female; Humans; Pregnancy; Pregnancy Complications; Treatment Outcome; Ursodeoxycholic Acid

2006
Ursodeoxycholic acid treatment in preterm infants: a pilot study for the prevention of cholestasis associated with total parenteral nutrition.
    Journal of pediatric gastroenterology and nutrition, 2008, Volume: 46, Issue:2

    Topics: Cholagogues and Choleretics; Cholestasis; Double-Blind Method; Fat Emulsions, Intravenous; Feces; Female; gamma-Glutamyltransferase; Humans; Infant; Infant, Newborn; Infant, Premature; Intestinal Absorption; Male; Nutritional Status; Parenteral Nutrition, Total; Pilot Projects; Prospective Studies; Safety; Treatment Outcome; Ursodeoxycholic Acid

2008
Prolonged treatment with ursodeoxycholic acid for primary biliary cirrhosis.
    La Clinica terapeutica, 1995, Volume: 146, Issue:5

    Topics: Adult; Cholestasis; Drug Evaluation; Female; Humans; Liver Cirrhosis, Biliary; Middle Aged; Pruritus; Treatment Outcome; Ursodeoxycholic Acid

1995
Preventing biliary stent occlusion.
    Lancet (London, England), 1994, Oct-15, Volume: 344, Issue:8929

    Topics: Bile Duct Neoplasms; Cholestasis; Humans; Stents; Ursodeoxycholic Acid

1994
Randomised trial of prevention of biliary stent occlusion by ursodeoxycholic acid plus norfloxacin.
    Lancet (London, England), 1994, Aug-27, Volume: 344, Issue:8922

    Topics: Administration, Oral; Bile Ducts; Cholestasis; Constriction, Pathologic; Drug Therapy, Combination; Humans; Norfloxacin; Stents; Ursodeoxycholic Acid

1994
The Canadian Multicenter Double-blind Randomized Controlled Trial of ursodeoxycholic acid in primary biliary cirrhosis.
    Hepatology (Baltimore, Md.), 1994, Volume: 19, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Alkaline Phosphatase; Bilirubin; Canada; Cholestasis; Cholesterol; Double-Blind Method; Female; Follow-Up Studies; Humans; Immunoglobulin M; Liver Cirrhosis, Biliary; Male; Middle Aged; Transaminases; Ursodeoxycholic Acid

1994
Effect of ursodeoxycholic acid treatment for cholestasis in liver transplant recipients.
    Transplantation proceedings, 1995, Volume: 27, Issue:6

    Topics: Adolescent; Adult; Alanine Transaminase; Bilirubin; Child; Child, Preschool; Cholestasis; gamma-Glutamyltransferase; Humans; Liver Transplantation; Middle Aged; Retrospective Studies; Ursodeoxycholic Acid

1995
Ursodeoxycholic acid therapy in pregnant women with cholestasis.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 1996, Volume: 52, Issue:2

    Topics: Adult; Bile Acids and Salts; Cholagogues and Choleretics; Cholestasis; Double-Blind Method; Female; Humans; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Treatment Outcome; Ursodeoxycholic Acid

1996
Evidence that ursodeoxycholic acid prevents steroid-resistant rejection in adult liver transplantation.
    Clinical transplantation, 1996, Volume: 10, Issue:6 Pt 2

    Topics: Adolescent; Adult; Anti-Inflammatory Agents; Cholagogues and Choleretics; Cholestasis; Drug Resistance; Female; Follow-Up Studies; Graft Rejection; Humans; Liver Transplantation; Male; Middle Aged; Pilot Projects; Recurrence; Ursodeoxycholic Acid

1996
Ileal absorption of bile acids in patients with chronic cholestasis: SeHCAT test results and effect of ursodeoxycholic acid (UDCA).
    Digestive diseases and sciences, 1996, Volume: 41, Issue:12

    Topics: Alkaline Phosphatase; Bile Acids and Salts; Cholestasis; Chronic Disease; Down-Regulation; Female; gamma-Glutamyltransferase; Humans; Ileum; Intestinal Absorption; Liver Cirrhosis; Male; Middle Aged; Selenium Radioisotopes; Taurocholic Acid; Up-Regulation; Ursodeoxycholic Acid

1996
Efficacy of ursodeoxycholic acid treatment and endoscopic dilation of major duct stenoses in primary sclerosing cholangitis. An 8-year prospective study.
    Journal of hepatology, 1997, Volume: 26, Issue:3

    Topics: Adolescent; Adult; Aged; Catheterization; Cholagogues and Choleretics; Cholangitis, Sclerosing; Cholestasis; Combined Modality Therapy; Endoscopy, Digestive System; Female; Follow-Up Studies; Humans; Male; Middle Aged; Predictive Value of Tests; Prospective Studies; Survival Rate; Treatment Outcome; Ursodeoxycholic Acid

1997
The effects of ursodeoxycholic acid in patients with severe obstructive jaundice after drainage procedure.
    Zhonghua yi xue za zhi = Chinese medical journal; Free China ed, 1997, Volume: 60, Issue:3

    Topics: Aged; Cholestasis; Drainage; Female; Humans; Male; Middle Aged; Ursodeoxycholic Acid

1997
Ursodeoxycholic acid inhibits eosinophil degranulation in patients with primary biliary cirrhosis.
    Hepatology (Baltimore, Md.), 1999, Volume: 30, Issue:1

    Topics: Blood Proteins; Cell Degranulation; Cholestasis; Eosinophil Granule Proteins; Eosinophil-Derived Neurotoxin; Eosinophils; Female; Hepatitis, Autoimmune; Hepatitis, Viral, Human; Humans; Immunohistochemistry; Leukocyte Count; Liver; Liver Cirrhosis, Biliary; Male; Placebos; Proteins; Radioimmunoassay; Ribonucleases; Ursodeoxycholic Acid

1999
Effect of ursodeoxycholic acid administration in patients with acute viral hepatitis: a pilot study.
    Alimentary pharmacology & therapeutics, 1999, Volume: 13, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholestasis; Cholic Acid; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Hepatitis Antibodies; Hepatitis Viruses; Hepatitis, Viral, Human; Humans; Male; Middle Aged; Pilot Projects; Reverse Transcriptase Polymerase Chain Reaction; RNA, Viral; Treatment Outcome; Ursodeoxycholic Acid

1999
Prevention of biliary stent occlusion by ursodeoxycholic acid plus norfloxacin: a multicenter randomized trial.
    Digestive diseases and sciences, 2000, Volume: 45, Issue:1

    Topics: Aged; Anti-Infective Agents; Cholagogues and Choleretics; Cholestasis; Female; Humans; Male; Norfloxacin; Prospective Studies; Stents; Time Factors; Treatment Outcome; Ursodeoxycholic Acid

2000
Ursodeoxycholic acid administration in patients with cholestasis of pregnancy: effects on primary bile acids in babies and mothers.
    Hepatology (Baltimore, Md.), 2001, Volume: 33, Issue:3

    Topics: Adult; Amniotic Fluid; Bile Acids and Salts; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholestasis; Cholic Acid; Dose-Response Relationship, Drug; Female; Fetal Blood; Humans; Infant, Newborn; Male; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Pruritus; Ursodeoxycholic Acid

2001
Ursodeoxycholic acid treatment of refractory chronic graft-versus-host disease of the liver.
    Annals of internal medicine, 1992, Apr-15, Volume: 116, Issue:8

    Topics: Bilirubin; Cholestasis; Chronic Disease; Graft vs Host Disease; Humans; Liver Diseases; Ursodeoxycholic Acid

1992
Ursodeoxycholic acid (UDCA) in the treatment of chronic cholestatic diseases.
    Biochimie, 1991, Volume: 73, Issue:10

    Topics: Animals; Cholestasis; Chronic Disease; Histocompatibility Antigens Class I; Humans; In Vitro Techniques; Liver Cirrhosis, Biliary; Major Histocompatibility Complex; Ursodeoxycholic Acid

1991
A randomized clinical trial of oral ursodeoxycholic acid in obstructive jaundice.
    The British journal of surgery, 1986, Volume: 73, Issue:8

    Topics: Administration, Oral; Adolescent; Adult; Aged; Cholestasis; Clinical Trials as Topic; Creatinine; Deoxycholic Acid; Endotoxins; Female; Humans; Intraoperative Complications; Male; Middle Aged; Premedication; Random Allocation; Toxemia; Ursodeoxycholic Acid

1986

Other Studies

234 other study(ies) available for ursodeoxycholic acid and Bile Duct Obstruction

ArticleYear
Molecular cloning and characterization of the murine bile salt export pump.
    Gene, 2000, Jan-04, Volume: 241, Issue:1

    Topics: 3T3 Cells; Amino Acid Sequence; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Blotting, Western; Cell Line; Cell Membrane; Cholagogues and Choleretics; Cholestasis; Cloning, Molecular; Humans; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Rats; Sequence Homology, Amino Acid; Taurocholic Acid; Transfection

2000
6alpha-ethyl-chenodeoxycholic acid (6-ECDCA), a potent and selective FXR agonist endowed with anticholestatic activity.
    Journal of medicinal chemistry, 2002, Aug-15, Volume: 45, Issue:17

    Topics: Animals; Anticholesteremic Agents; Cell Line; Chenodeoxycholic Acid; Cholestasis; DNA-Binding Proteins; Humans; Ligands; Liver; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Structure-Activity Relationship; Transcription Factors

2002
Adjunct Fenofibrate Up-regulates Bile Acid Glucuronidation and Improves Treatment Response For Patients With Cholestasis.
    Hepatology communications, 2021, Volume: 5, Issue:12

    Topics: Adult; Bile Acids and Salts; Cholangitis, Sclerosing; Cholestasis; Drug Therapy, Combination; Female; Fenofibrate; Glucuronides; Hepatocytes; Humans; Liver; Liver Cirrhosis, Biliary; Liver Function Tests; Male; Middle Aged; PPAR alpha; Retrospective Studies; Treatment Outcome; Up-Regulation; Ursodeoxycholic Acid; Young Adult

2021
Heterozygous mutations of ATP8B1, ABCB11 and ABCB4 cause mild forms of Progressive Familial Intrahepatic Cholestasis in a pediatric cohort.
    Gastroenterologia y hepatologia, 2022, Volume: 45, Issue:8

    Topics: Adenosine Triphosphatases; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; Bile Acids and Salts; Bilirubin; Child; Child, Preschool; Cholestasis; Cholestasis, Intrahepatic; gamma-Glutamyltransferase; Humans; Mutation; Pruritus; Retrospective Studies; Transaminases; Ursodeoxycholic Acid

2022
Review of Medical Management of Primary Biliary Cholangitis.
    South Dakota medicine : the journal of the South Dakota State Medical Association, 2021, Volume: 74, Issue:12

    Topics: Cholagogues and Choleretics; Cholestasis; Disease Progression; Humans; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

2021
Primary biliary cholangitis first demonstrated in pregnancy: a case report.
    Journal of medical case reports, 2022, Jan-31, Volume: 16, Issue:1

    Topics: Adult; Cesarean Section; Cholestasis; Cholestasis, Intrahepatic; Female; Humans; Liver Cirrhosis, Biliary; Pregnancy; Ursodeoxycholic Acid

2022
TREM-2 plays a protective role in cholestasis by acting as a negative regulator of inflammation.
    Journal of hepatology, 2022, Volume: 77, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Cholestasis; Inflammation; Interleukin-33; Lipopolysaccharides; Liver; Membrane Glycoproteins; Mice; Receptors, Immunologic; Triggering Receptor Expressed on Myeloid Cells-1; Ursodeoxycholic Acid

2022
One case of arthrogryposis-renal dysfunction-cholestasis (ARC) syndrome featuring an incomplete and mild phenotype.
    BMC nephrology, 2022, 06-27, Volume: 23, Issue:1

    Topics: Arthrogryposis; Bilirubin; Cholestasis; Female; Humans; Jaundice, Obstructive; Mutation; Phenotype; Pruritus; Renal Insufficiency; Ursodeoxycholic Acid; Vesicular Transport Proteins

2022
Rolling stones: an instructive case of neonatal cholestasis.
    BMC pediatrics, 2022, 09-04, Volume: 22, Issue:1

    Topics: Biliary Atresia; Choledocholithiasis; Cholestasis; Humans; Hyperbilirubinemia; Infant; Infant, Newborn; Infant, Newborn, Diseases; Jaundice, Neonatal; Liver Diseases; Male; Ursodeoxycholic Acid

2022
Perinatal exposure to UDCA prevents neonatal cholestasis in Cyp2c70
    Pediatric research, 2023, Volume: 93, Issue:6

    Topics: Animals; Bile Acids and Salts; Cholestasis; Female; Humans; Infant, Newborn; Liver Diseases; Male; Mice; Pregnancy; Ursodeoxycholic Acid

2023
Fluorofenidone ameliorates cholestasis and fibrosis by inhibiting hepatic Erk/-Egr-1 signaling and Tgfβ1/Smad pathway in mice.
    Biochimica et biophysica acta. Molecular basis of disease, 2022, 12-01, Volume: 1868, Issue:12

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; Bile Acids and Salts; Cholestasis; Fibrosis; Inflammation; Interleukin-6; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Pyridones; Tumor Necrosis Factor-alpha; Ursodeoxycholic Acid

2022
Resveratrol modulates the gut microbiota of cholestasis in pregnant rats.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2022, Volume: 73, Issue:2

    Topics: Alanine; Alanine Transaminase; Animals; Aspartic Acid; Bile Acids and Salts; Cholestasis; Cholestasis, Intrahepatic; Dysbiosis; Ethinyl Estradiol; Female; Gastrointestinal Microbiome; Glutamates; Pregnancy; Pregnancy Complications; Rats; Resveratrol; RNA, Ribosomal, 16S; Ursodeoxycholic Acid

2022
[Ursodeoxycholic acid: history and clinical implications].
    Nederlands tijdschrift voor geneeskunde, 2022, 09-28, Volume: 166

    Topics: Bicarbonates; Bile Acids and Salts; Chlorides; Cholagogues and Choleretics; Cholestasis; Humans; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

2022
Effect of ursodeoxycholic acid after self-expandable metal stent placement in malignant distal biliary obstruction: a propensity score-matched cohort analysis.
    Gastrointestinal endoscopy, 2023, Volume: 97, Issue:4

    Topics: Cholestasis; Cohort Studies; Humans; Propensity Score; Retrospective Studies; Self Expandable Metallic Stents; Sewage; Stents; Ursodeoxycholic Acid

2023
Ursodeoxycholic acid use in lactating female patients is associated with clinically negligible concentrations of this bile acid in breast milk.
    Scientific reports, 2022, 11-15, Volume: 12, Issue:1

    Topics: Bile Acids and Salts; Cholestasis; Female; Humans; Infant, Newborn; Lactation; Milk, Human; Ursodeoxycholic Acid

2022
L-carbocisteine can cause cholestasis with vanishing bile duct syndrome in children: A case report.
    Medicine, 2022, Nov-11, Volume: 101, Issue:45

    Topics: Bile Ducts, Intrahepatic; Bilirubin; Carbocysteine; Child; Cholestasis; Female; Humans; Jaundice; Syndrome; Ursodeoxycholic Acid

2022
A novel therapy for hepatic cholestasis treatment-the combination of rosiglitazone and fenofibrate.
    European journal of pharmacology, 2023, Jan-05, Volume: 938

    Topics: Animals; Cholestasis; Fenofibrate; Liver; Mice; Mice, Inbred C57BL; Necrosis; Rosiglitazone; Ursodeoxycholic Acid

2023
Application of the Latest Advances in Evidence-Based Medicine in Primary Biliary Cholangitis.
    The American journal of gastroenterology, 2023, 02-01, Volume: 118, Issue:2

    Topics: Cholangitis; Cholestasis; Evidence-Based Medicine; Humans; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

2023
Management of Primary Biliary Cholangitis: Current Treatment and Future Perspectives.
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2023, Volume: 34, Issue:2

    Topics: Cholagogues and Choleretics; Cholangitis; Cholestasis; Humans; Liver Cirrhosis, Biliary; Receptors, Cytoplasmic and Nuclear; Ursodeoxycholic Acid

2023
Primary biliary cholangitis: Epidemiology, prognosis, and treatment.
    Hepatology communications, 2023, 06-01, Volume: 7, Issue:6

    Topics: Cholangitis; Cholestasis; Female; Humans; Liver Cirrhosis, Biliary; Male; Prognosis; Ursodeoxycholic Acid

2023
Characterization of Metabolic Correlations of Ursodeoxycholic Acid with Other Bile Acid Species through In Vitro Sequential Metabolism and Isomer-Focused Identification.
    Molecules (Basel, Switzerland), 2023, Jun-16, Volume: 28, Issue:12

    Topics: Bile Acids and Salts; Cholestasis; Glucuronides; Humans; Mass Spectrometry; Ursodeoxycholic Acid

2023
[Primary biliary cholangitis. Experience in 179 patients].
    Revista medica de Chile, 2022, Volume: 150, Issue:7

    Topics: Adult; Aged; Autoantibodies; Autoimmune Diseases; Cholestasis; Female; Humans; Liver Cirrhosis, Biliary; Middle Aged; Retrospective Studies; Ursodeoxycholic Acid; Young Adult

2022
Probiotic Lactobacillus rhamnosus GG prevents progesterone metabolite epiallaopregnanolone sulfate-induced hepatic bile acid accumulation and liver injury.
    Biochemical and biophysical research communications, 2019, 11-26, Volume: 520, Issue:1

    Topics: Angiogenic Proteins; Animals; Bile Acids and Salts; Bilirubin; Chenodeoxycholic Acid; Cholestasis; Cholesterol 7-alpha-Hydroxylase; Cholic Acid; Cytokines; Disease Models, Animal; Gastrointestinal Microbiome; Inflammation; Lacticaseibacillus rhamnosus; Liver; Male; Mice; Mice, Inbred C57BL; Pregnanolone; Probiotics; RNA-Binding Proteins; Signal Transduction; Ursodeoxycholic Acid

2019
Bile acids and bilirubin effects on osteoblastic gene profile. Implications in the pathogenesis of osteoporosis in liver diseases.
    Gene, 2020, Jan-30, Volume: 725

    Topics: Apoptosis; Bile Acids and Salts; Bilirubin; Cell Line, Tumor; Cholestasis; Down-Regulation; Genetic Profile; Humans; Lithocholic Acid; Liver; Liver Diseases; Osteoblasts; Osteoporosis; Osteosarcoma; Up-Regulation; Ursodeoxycholic Acid

2020
Cholestatic Liver Injury Induced by Pembrolizumab in a Patient with Lung Adenocarcinoma.
    Internal medicine (Tokyo, Japan), 2019, Volume: 58, Issue:22

    Topics: Adenocarcinoma of Lung; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological; Cholestasis; Humans; Lung Neoplasms; Male; Middle Aged; Treatment Outcome; Ursodeoxycholic Acid

2019
The value of routine laboratory screening in the neonatal intensive care unit.
    Journal of neonatal-perinatal medicine, 2020, Volume: 13, Issue:2

    Topics: Alkaline Phosphatase; Anemia; Bilirubin; Bone Density Conservation Agents; Bone Diseases, Metabolic; Cholagogues and Choleretics; Cholestasis; Diagnostic Tests, Routine; Erythrocyte Transfusion; Female; Gestational Age; Health Care Costs; Health Expenditures; Hematocrit; Humans; Infant, Extremely Premature; Infant, Newborn; Infant, Premature; Intensive Care Units, Neonatal; Liver Function Tests; Male; Mass Screening; Parenteral Nutrition, Total; Patient Selection; Retrospective Studies; Ursodeoxycholic Acid; Vitamin D

2020
Refractory pruritus from malignant cholestasis: management.
    BMJ supportive & palliative care, 2023, Volume: 13, Issue:e1

    Topics: Cholestasis; Cholestyramine Resin; Humans; Pruritus; Ursodeoxycholic Acid

2023
FXR-dependent Rubicon induction impairs autophagy in models of human cholestasis.
    Journal of hepatology, 2020, Volume: 72, Issue:6

    Topics: Autophagosomes; Autophagy; Autophagy-Related Proteins; Chenodeoxycholic Acid; Cholestasis; Cytotoxins; Gene Knockdown Techniques; Hep G2 Cells; Humans; Liver; Lysosomes; Receptors, Cytoplasmic and Nuclear; Retrospective Studies; Signal Transduction; Transfection; Ursodeoxycholic Acid

2020
Does ursodeoxycholic acid have a role in the treatment of women with intrahepatic (obstetric) cholestasis of pregnancy anymore?
    BMJ evidence-based medicine, 2021, Volume: 26, Issue:2

    Topics: Cholestasis; Female; Humans; Pregnancy; Pregnancy Complications; Ursodeoxycholic Acid

2021
Ursodeoxycholic acid use is associated with significant risk of morbidity and mortality in infants with cholestasis: A strobe compliant study.
    Medicine, 2020, Volume: 99, Issue:7

    Topics: Case-Control Studies; Cholestasis; Egypt; Female; Humans; Infant; Infant, Newborn; Male; Off-Label Use; Postoperative Complications; Retrospective Studies; Severity of Illness Index; Ursodeoxycholic Acid

2020
Ursodeoxycholic acid therapy throughout pregnancy in women affected with chronic cholestasis of childhood: No evidence for teratogenicity.
    Clinics and research in hepatology and gastroenterology, 2021, Volume: 45, Issue:3

    Topics: Cholagogues and Choleretics; Cholestasis; Cholestasis, Intrahepatic; Female; Humans; Pregnancy; Pregnancy Complications; Ursodeoxycholic Acid

2021
NISCH syndrome: An extremely rare cause of neonatal cholestasis.
    Journal of hepatology, 2020, Volume: 73, Issue:5

    Topics: Alopecia; Cholagogues and Choleretics; Cholangitis, Sclerosing; Cholestasis; Claudin-1; Female; Genetic Testing; Humans; Hyperbilirubinemia; Ichthyosis; Infant, Newborn; Leukocyte Disorders; Liver Function Tests; Mutation; Transaminases; Ursodeoxycholic Acid; Vitamins

2020
Chronic cholestatic liver diseases - Primary biliary cholangitis and Primary sclerosing cholangitis.
    Vnitrni lekarstvi, 2020,Spring, Volume: 66, Issue:5

    Topics: Bile Ducts; Cholangitis, Sclerosing; Cholestasis; Humans; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

2020
Protective Functions of ZO-2/Tjp2 Expressed in Hepatocytes and Cholangiocytes Against Liver Injury and Cholestasis.
    Gastroenterology, 2021, Volume: 160, Issue:6

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B, Member 11; Bile Acids and Salts; Bile Canaliculi; Chemical and Drug Induced Liver Injury; Cholagogues and Choleretics; Cholestasis; Cholic Acid; Claudin-1; Cytochrome P450 Family 2; Cytoskeletal Proteins; Epithelial Cells; Female; Fibrosis; Genetic Predisposition to Disease; Hepatocytes; Male; Membrane Proteins; Mice; Mice, Knockout; Mutation; Oxazoles; Permeability; Protective Factors; RNA, Messenger; Steroid Hydroxylases; Tight Junctions; Ursodeoxycholic Acid; Zonula Occludens-2 Protein

2021
Anti-mitochondrial Antibody-Negative Primary Biliary Cholangitis Is Part of the Same Spectrum of Classical Primary Biliary Cholangitis.
    Digestive diseases and sciences, 2022, Volume: 67, Issue:7

    Topics: Autoantibodies; Cholestasis; Diabetes Mellitus, Type 2; Female; Humans; Liver Cirrhosis, Biliary; Male; Middle Aged; Mitochondria; Ursodeoxycholic Acid

2022
Omega-3 Polyunsaturated Fatty Acid: A Pharmaco-Nutraceutical Approach to Improve the Responsiveness to Ursodeoxycholic Acid.
    Nutrients, 2021, Jul-29, Volume: 13, Issue:8

    Topics: Apoptosis; Autoimmune Diseases; Bile Acids and Salts; Carcinoma, Hepatocellular; Caspase 3; Cholangitis, Sclerosing; Cholestanetriol 26-Monooxygenase; Cholestasis; Cholesterol 7-alpha-Hydroxylase; Dietary Supplements; Down-Regulation; Drug Therapy, Combination; Endoplasmic Reticulum Stress; Fatty Acids, Omega-3; Gene Expression; Hep G2 Cells; Humans; Inflammation; Liver; Liver Cirrhosis, Biliary; Liver Diseases; THP-1 Cells; Ursodeoxycholic Acid

2021
Primary Biliary Cholangitis: advances in management and treatment of the disease.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2017, Volume: 49, Issue:8

    Topics: Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholangitis; Cholestasis; Disease Progression; Drug Therapy, Combination; End Stage Liver Disease; Humans; Ursodeoxycholic Acid

2017
Primary sclerosing cholangitis: Ursodeoxycholic acid derivative: safe and effective.
    Nature reviews. Gastroenterology & hepatology, 2017, Volume: 14, Issue:7

    Topics: Cholagogues and Choleretics; Cholangitis, Sclerosing; Cholestasis; Humans; Ursodeoxycholic Acid

2017
24-Norursodeoxycholic acid in patients with primary sclerosing cholangitis: A new "urso saga" on the horizon?
    Journal of hepatology, 2017, Volume: 67, Issue:3

    Topics: Cholangitis, Sclerosing; Cholestasis; Humans; Ursodeoxycholic Acid

2017
A case of Alagille syndrome presenting with chronic cholestasis in an adult.
    Clinical and molecular hepatology, 2017, Volume: 23, Issue:3

    Topics: Adult; Alagille Syndrome; Alkaline Phosphatase; Cholestasis; gamma-Glutamyltransferase; Humans; Liver; Male; Tomography, X-Ray Computed; Ultrasonography; Ursodeoxycholic Acid

2017
Ursodeoxycholic acid prevents ventricular conduction slowing and arrhythmia by restoring T-type calcium current in fetuses during cholestasis.
    PloS one, 2017, Volume: 12, Issue:9

    Topics: Animals; Calcium; Calcium Channels, T-Type; Cholestasis; Electrophysiological Phenomena; Female; Fetal Heart; Heart Ventricles; Humans; Myocytes, Cardiac; Pregnancy; Rats; Taurocholic Acid; Ursodeoxycholic Acid

2017
Increased cholestatic enzymes in two patients with long-term history of ulcerative colitis: consider primary biliary cholangitis not always primary sclerosing cholangitis.
    BMJ case reports, 2017, Sep-25, Volume: 2017

    Topics: Aged; Autoantibodies; Cholagogues and Choleretics; Cholangiopancreatography, Endoscopic Retrograde; Cholestasis; Colitis, Ulcerative; Diagnosis, Differential; Female; Humans; Liver Cirrhosis, Biliary; Liver Function Tests; Male; Treatment Outcome; Ursodeoxycholic Acid

2017
Adult idiopathic cholestasis: a condition more common in the Canadian Inuit?
    International journal of circumpolar health, 2017, Volume: 76, Issue:1

    Topics: Adult; Aged; Canada; Cholestasis; Female; Humans; Immunomodulation; Inuit; Male; Middle Aged; Ursodeoxycholic Acid

2017
Treatment with milk thistle extract (Silybum marianum), ursodeoxycholic acid, or their combination attenuates cholestatic liver injury in rats: Role of the hepatic stem cells.
    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology, 2017, Volume: 28, Issue:6

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cholagogues and Choleretics; Cholestasis; Disease Models, Animal; Drug Therapy, Combination; Female; Hepatocytes; Liver; Liver Cirrhosis; Malondialdehyde; Peroxidase; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Silybum marianum; Stem Cells; Ursodeoxycholic Acid

2017
Galactosylated Pro-Drug of Ursodeoxycholic Acid: Design, Synthesis, Characterization, and Pharmacological Effects in a Rat Model of Estrogen-Induced Cholestasis.
    Molecular pharmaceutics, 2018, 01-02, Volume: 15, Issue:1

    Topics: Animals; Cholestasis; Cyclooxygenase 2; Estrogens; Ethinyl Estradiol; Hep G2 Cells; Humans; Interleukin-1beta; Male; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Prodrugs; Rats; Rats, Wistar; Solubility; Tumor Necrosis Factor-alpha; Ursodeoxycholic Acid

2018
Effects of corilagin on alleviating cholestasis via farnesoid X receptor-associated pathways in vitro and in vivo.
    British journal of pharmacology, 2018, Volume: 175, Issue:5

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Cell Survival; Cells, Cultured; Cholestasis; Cholesterol 7-alpha-Hydroxylase; Cytochrome P450 Family 7; Dexamethasone; Down-Regulation; Glucosides; Glucuronosyltransferase; Humans; Hydrolyzable Tannins; Isoxazoles; Liver; Male; Organic Anion Transporters, Sodium-Dependent; Pregnenediones; Primary Cell Culture; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Rats; Receptors, Cytoplasmic and Nuclear; RNA, Small Interfering; Steroid Hydroxylases; Sulfotransferases; Symporters; Up-Regulation; Ursodeoxycholic Acid

2018
Erythropoietic Protoporphyria: Initial Diagnosis With Cholestatic Liver Disease.
    Pediatrics, 2018, Volume: 141, Issue:Suppl 5

    Topics: beta Carotene; Child; Cholagogues and Choleretics; Cholestasis; Cholestyramine Resin; Chronic Disease; Diagnosis, Differential; Humans; Male; Photosensitivity Disorders; Protoporphyria, Erythropoietic; Provitamins; Pruritus; Ursodeoxycholic Acid

2018
Autoimmune Pancreatitis and Ulcerative Rectocolitis in an Adolescent.
    Pediatrics, 2018, Volume: 141, Issue:Suppl 5

    Topics: Acute Disease; Adolescent; Adrenal Cortex Hormones; Autoimmune Diseases; Azathioprine; Biopsy; Cholagogues and Choleretics; Cholangiopancreatography, Magnetic Resonance; Cholestasis; Diagnosis, Differential; Humans; Immunoglobulin G; Immunosuppressive Agents; Liver Cirrhosis; Male; Pancreatic Neoplasms; Pancreatitis; Proctocolitis; Ultrasonography; Ursodeoxycholic Acid

2018
Pediatric cirrhotic cardiomyopathy: Impact on liver transplant outcomes.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2018, Volume: 24, Issue:6

    Topics: Adolescent; Cardiomyopathies; Child; Child, Preschool; Cholagogues and Choleretics; Cholestasis; Echocardiography; Electrocardiography; End Stage Liver Disease; Female; Humans; Incidence; Infant; Length of Stay; Liver Cirrhosis; Liver Transplantation; Male; Retrospective Studies; Survival Rate; Treatment Outcome; Ursodeoxycholic Acid

2018
Ursodeoxycholate Restores Biliary Excretion of Methotrexate in Rats with Ethinyl Estradiol Induced-Cholestasis by Restoring Canalicular Mrp2 Expression.
    International journal of molecular sciences, 2018, Apr-09, Volume: 19, Issue:4

    Topics: Administration, Oral; Animals; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cholestasis; Down-Regulation; Drug Administration Schedule; Ethinyl Estradiol; Male; Methotrexate; Multidrug Resistance-Associated Protein 2; Rats; Treatment Outcome; Ursodeoxycholic Acid

2018
Paternal cholestasis exacerbates obesity-associated hypertension in male offspring but is prevented by paternal ursodeoxycholic acid treatment.
    International journal of obesity (2005), 2019, Volume: 43, Issue:2

    Topics: Animals; Body Weight; Cholestasis; Diet, Western; Fathers; Female; Hypertension; Male; Mice; Mice, Inbred C57BL; Obesity; Ursodeoxycholic Acid

2019
How best to manage chronic cholestasis.
    The Journal of family practice, 2018, Volume: 67, Issue:7

    Topics: Adult; Cholagogues and Choleretics; Cholestasis; Chronic Disease; Disease Management; Family Practice; Female; Humans; Practice Guidelines as Topic; Treatment Outcome; Ursodeoxycholic Acid

2018
Utility of liver biopsy in the evaluation of pediatric total parenteral nutrition cholestasis.
    American journal of surgery, 2018, Volume: 216, Issue:4

    Topics: Biopsy; Cholagogues and Choleretics; Cholestasis; Clinical Decision-Making; Combined Modality Therapy; Female; Humans; Infant, Newborn; Liver; Male; Parenteral Nutrition, Total; Practice Patterns, Physicians'; Retrospective Studies; Treatment Outcome; Ursodeoxycholic Acid

2018
Adherence to ursodeoxycholic acid therapy in patients with cholestatic and autoimmune liver disease.
    Clinics and research in hepatology and gastroenterology, 2019, Volume: 43, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Autoimmune Diseases; Cholagogues and Choleretics; Cholestasis; Female; Humans; Liver Diseases; Male; Medication Adherence; Middle Aged; Prospective Studies; Ursodeoxycholic Acid; Young Adult

2019
[Research progress on risk factors for poor response of ursodeoxycholic acid in primary biliary cholangitis].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2019, Jan-20, Volume: 27, Issue:1

    Topics: Cholagogues and Choleretics; Cholangitis; Cholestasis; Humans; Liver Cirrhosis, Biliary; Risk Factors; Ursodeoxycholic Acid

2019
Cholestasis affects enteral tolerance and prospective weight gain in the NICU.
    Clinical nutrition ESPEN, 2019, Volume: 30

    Topics: Bilirubin; Birth Weight; Cholagogues and Choleretics; Cholestasis; Digestive System Surgical Procedures; Disease Progression; Fat Emulsions, Intravenous; Female; Fibrosis; Fish Oils; Humans; Hyperbilirubinemia; Infant; Infant Nutritional Physiological Phenomena; Infant, Newborn; Infant, Premature; Intensive Care Units, Neonatal; Male; Parenteral Nutrition; Postoperative Complications; Prognosis; Retrospective Studies; Ursodeoxycholic Acid; Weight Gain

2019
Anticholestatic mechanisms of ursodeoxycholic acid in lipopolysaccharide-induced cholestasis.
    Biochemical pharmacology, 2019, Volume: 168

    Topics: Alkaline Phosphatase; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cholagogues and Choleretics; Cholestasis; Disease Models, Animal; Hepatocytes; Lipopolysaccharides; Liver; Male; Rats; Rats, Wistar; Treatment Outcome; Ursodeoxycholic Acid

2019
A case of primary biliary cholangitis overlapping with type 2 autoimmune hepatitis.
    Clinical journal of gastroenterology, 2020, Volume: 13, Issue:1

    Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Autoantibodies; Cholagogues and Choleretics; Cholestasis; Female; Glucocorticoids; Hepatitis, Autoimmune; Humans; Immunoglobulin G; Immunoglobulin M; Liver Cirrhosis, Biliary; Mitochondrial Proteins; Prednisolone; Ursodeoxycholic Acid

2020
Ursodeoxycholic acid increases differentiation and mineralization and neutralizes the damaging effects of bilirubin on osteoblastic cells.
    Liver international : official journal of the International Association for the Study of the Liver, 2013, Volume: 33, Issue:7

    Topics: Bilirubin; Calcification, Physiologic; Cell Differentiation; Cell Line, Tumor; Cell Survival; Cholestasis; Humans; Jaundice; Lithocholic Acid; Osteoblasts; Osteoporosis; Statistics, Nonparametric; Ursodeoxycholic Acid

2013
Anti-inflammatory and anti-oxidative effects of corilagin in a rat model of acute cholestasis.
    BMC gastroenterology, 2013, May-03, Volume: 13

    Topics: Acute Disease; Alanine Transaminase; Analysis of Variance; Animals; Anti-Inflammatory Agents; Aspartate Aminotransferases; Bilirubin; Cholagogues and Choleretics; Cholestasis; Dexamethasone; Disease Models, Animal; Glucosides; Hydrolyzable Tannins; Liver; Male; Malondialdehyde; NF-kappa B; Nitric Oxide; Oxidative Stress; Peroxidase; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Ursodeoxycholic Acid

2013
Defective canalicular transport and toxicity of dietary ursodeoxycholic acid in the abcb11-/- mouse: transport and gene expression studies.
    American journal of physiology. Gastrointestinal and liver physiology, 2013, Aug-15, Volume: 305, Issue:4

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Bile Canaliculi; Biological Transport; Cholestasis; Diet; Disease Models, Animal; Gene Expression Regulation; Infusions, Intravenous; Liver; Mice; Mice, Knockout; Multidrug Resistance-Associated Proteins; RNA, Messenger; Taurochenodeoxycholic Acid; Time Factors; Ursodeoxycholic Acid

2013
Bile acids trigger cholemic nephropathy in common bile-duct-ligated mice.
    Hepatology (Baltimore, Md.), 2013, Volume: 58, Issue:6

    Topics: Animals; Bile Acids and Salts; Cholestasis; Common Bile Duct; Disease Models, Animal; Kidney Diseases; Kidney Tubules; Ligation; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nephritis, Interstitial; Receptors, Cytoplasmic and Nuclear; Ursodeoxycholic Acid

2013
[Effects of ursodeoxycholic acid on mRNA expression of MDR3 and FXR in infants with cholestatic hepatitis].
    Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2013, Volume: 15, Issue:9

    Topics: ATP Binding Cassette Transporter, Subfamily B; Cholestasis; Female; Gene Expression Regulation; Hepatitis; Humans; Infant; Male; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Ursodeoxycholic Acid

2013
Ursodeoxycholic acid induced generalized fixed drug eruption.
    Cutaneous and ocular toxicology, 2014, Volume: 33, Issue:3

    Topics: Anti-Inflammatory Agents; Cetirizine; Cholestasis; Drug Eruptions; Gallstones; Histamine H1 Antagonists, Non-Sedating; Humans; Male; Middle Aged; Mometasone Furoate; Pregnadienediols; Skin; Ursodeoxycholic Acid

2014
Liver protective effect of ursodeoxycholic acid includes regulation of ADAM17 activity.
    BMC gastroenterology, 2013, Oct-30, Volume: 13

    Topics: ADAM Proteins; ADAM17 Protein; Animals; Bile Ducts; Cholagogues and Choleretics; Cholestasis; Hep G2 Cells; Hepatocytes; Humans; Ligation; Liver; MAP Kinase Signaling System; Mice; Proto-Oncogene Proteins c-met; Transforming Growth Factor alpha; Tumor Necrosis Factor-alpha; Ursodeoxycholic Acid

2013
Alagille syndrome: experience of a tertiary care center in North India.
    Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2014, Volume: 33, Issue:1

    Topics: Alagille Syndrome; Calcium, Dietary; Child; Child, Preschool; Cholagogues and Choleretics; Cholestasis; Cholestyramine Resin; Energy Intake; Female; Humans; India; Infant; Male; Prognosis; Pruritus; Recommended Dietary Allowances; Rifampin; Tertiary Care Centers; Triglycerides; Ursodeoxycholic Acid; Vitamins

2014
All-trans-retinoic acid improves cholestasis in α-naphthylisothiocyanate-treated rats and Mdr2-/- mice.
    The Journal of pharmacology and experimental therapeutics, 2014, Volume: 349, Issue:1

    Topics: 1-Naphthylisothiocyanate; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Bile Acids and Salts; Cell Proliferation; Cholagogues and Choleretics; Cholestasis; Chronic Disease; Disease Models, Animal; Drug Therapy, Combination; Liver; Male; Mice; Mice, Knockout; Rats; Rats, Sprague-Dawley; Tretinoin; Ursodeoxycholic Acid

2014
[Biliary sludge: diagnosis and treatment at an outpatient's clinic].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2013, Issue:9

    Topics: Ambulatory Care; Bile; Cholagogues and Choleretics; Cholestasis; Female; Gallbladder; Humans; Male; Middle Aged; Ultrasonography; Ursodeoxycholic Acid

2013
Ursodeoxycholyl lysophosphatidylethanolamide inhibits cholestasis- and hypoxia-induced apoptosis by upregulating antiapoptosis proteins.
    Experimental biology and medicine (Maywood, N.J.), 2015, Volume: 240, Issue:2

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Cholestasis; Glycochenodeoxycholic Acid; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Liver; Mice; Myeloid Cell Leukemia Sequence 1 Protein; Phosphatidylethanolamines; Phosphorylation; Up-Regulation; Ursodeoxycholic Acid

2015
Vanishing bile duct syndrome and immunodeficiency preceding the diagnosis of Hodgkin lymphoma.
    Internal medicine journal, 2014, Volume: 44, Issue:12a

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bile Ducts, Intrahepatic; Bleomycin; Cholagogues and Choleretics; Cholestasis; Doxorubicin; Hodgkin Disease; Humans; Immunocompromised Host; Male; Neutropenia; Syndrome; Treatment Outcome; Ursodeoxycholic Acid

2014
Ursodeoxycholic acid alleviates cholestasis-induced histophysiological alterations in the male reproductive system of bile duct-ligated rats.
    Reproductive toxicology (Elmsford, N.Y.), 2014, Volume: 50

    Topics: Animals; Body Weight; Cholestasis; Epididymis; Ligation; Liver; Male; Nitric Oxide; Organ Size; Prostate-Specific Antigen; Rats; Rats, Wistar; Testis; Ursodeoxycholic Acid

2014
Natural history of conjugated bilirubin trajectory in neonates following parenteral nutrition cessation.
    BMC pediatrics, 2014, Dec-10, Volume: 14

    Topics: Bilirubin; Cholagogues and Choleretics; Cholestasis; Female; Humans; Infant, Newborn; Intensive Care Units, Neonatal; Male; Parenteral Nutrition; Retrospective Studies; Sepsis; Time Factors; Ursodeoxycholic Acid; Withholding Treatment

2014
Ursodeoxycholic acid versus phenobarbital pretreatment prior to hepatobiliary scintigraphy in neonatal cholestasis: is it time for shifting gears towards a practice change?
    European journal of nuclear medicine and molecular imaging, 2015, Volume: 42, Issue:7

    Topics: Biliary Tract; Cholagogues and Choleretics; Cholestasis; Humans; Hypnotics and Sedatives; Infant; Liver; Perfusion Imaging; Phenobarbital; Ursodeoxycholic Acid

2015
Autoimmune hepatitis-primary biliary cirrhosis concurrent with biliary stricture after liver transplantation.
    World journal of gastroenterology, 2015, Feb-21, Volume: 21, Issue:7

    Topics: Cholagogues and Choleretics; Cholestasis; Fatty Liver, Alcoholic; Hepatitis, Autoimmune; Humans; Immunosuppressive Agents; Liver Cirrhosis, Biliary; Liver Function Tests; Liver Transplantation; Male; Middle Aged; Prednisone; Tacrolimus; Treatment Outcome; Ursodeoxycholic Acid

2015
Comparison of phenobarbitone and ursodeoxycholic acid in drug-augmented hepatobiliary scintigraphy for excluding the diagnosis of obstructive cholestasis in neonatal cholestasis syndrome.
    Nuclear medicine communications, 2015, Volume: 36, Issue:8

    Topics: Biliary Tract; Cholestasis; Female; Humans; Infant; Infant, Newborn; Liver; Male; Phenobarbital; Radionuclide Imaging; Ursodeoxycholic Acid

2015
[Morpho-functional changes in the liver and the possibility of their correction in the offspring of rats with cholestasis].
    Morfologiia (Saint Petersburg, Russia), 2015, Volume: 147, Issue:1

    Topics: Animals; Cholestasis; Female; Hepatocytes; Humans; Liver; Lysosomes; Maternal-Fetal Relations; NADH Dehydrogenase; Pregnancy; Rats; Succinate Dehydrogenase; Ursodeoxycholic Acid

2015
Testicular immunohistochemical and Ultrastructural changes associated with chronic cholestasis in rats: Effect of ursodeoxycholic acid.
    Life sciences, 2015, Sep-01, Volume: 136

    Topics: Animals; Cholagogues and Choleretics; Cholestasis; Drug Evaluation, Preclinical; Immunohistochemistry; Male; Rats, Wistar; Spermatogenesis; Testicular Diseases; Testis; Ursodeoxycholic Acid

2015
Drug augmented hepatobiliary scintigraphy for evaluation of neonatal cholestasis: what does the evidence point to?
    Nuclear medicine communications, 2015, Volume: 36, Issue:9

    Topics: Biliary Tract; Cholestasis; Female; Humans; Liver; Male; Phenobarbital; Radionuclide Imaging; Ursodeoxycholic Acid

2015
Drug-augmented hepatobiliary scintigraphy for evaluation of neonatal cholestasis: What does the evidence point to?
    Nuclear medicine communications, 2015, Volume: 36, Issue:9

    Topics: Biliary Tract; Cholestasis; Female; Humans; Liver; Male; Phenobarbital; Radionuclide Imaging; Ursodeoxycholic Acid

2015
Influence of 24-Nor-Ursodeoxycholic Acid on Hepatic Disposition of [(18)F]Ciprofloxacin, a Positron Emission Tomography Study in Mice.
    Journal of pharmaceutical sciences, 2016, Volume: 105, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Biological Transport; CHO Cells; Cholestasis; Ciprofloxacin; Cricetulus; Disease Models, Animal; Female; Fluorine Radioisotopes; Liver; Mice, Knockout; Multidrug Resistance-Associated Proteins; Organ Specificity; Positron-Emission Tomography; Substrate Specificity; Tissue Distribution; Ursodeoxycholic Acid

2016
UDCA and CDCA alleviate 17α-ethinylestradiol-induced cholestasis through PKA-AMPK pathways in rats.
    Toxicology and applied pharmacology, 2016, Nov-15, Volume: 311

    Topics: Adenylate Kinase; Animals; Carrier Proteins; Cells, Cultured; Chenodeoxycholic Acid; Cholestasis; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; Ethinyl Estradiol; Female; Male; Membrane Glycoproteins; Phosphorylation; Pregnancy; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Ursodeoxycholic Acid

2016
Chronic Pruritus in an 18-Month-Old Male Infant Due to Anicteric Cholestasis.
    Journal of tropical pediatrics, 2017, 08-01, Volume: 63, Issue:4

    Topics: ATP Binding Cassette Transporter, Subfamily B; Biopsy; Cholestasis; Cholestasis, Intrahepatic; Chronic Disease; Humans; Infant; Liver; Male; Pruritus; Treatment Outcome; Ursodeoxycholic Acid

2017
NorUrsodeoxycholic acid ameliorates cholemic nephropathy in bile duct ligated mice.
    Journal of hepatology, 2017, Volume: 67, Issue:1

    Topics: Animals; Bile Acids and Salts; Cholestasis; Disease Models, Animal; Fibrosis; Kidney; Kidney Diseases; Ligation; Lipocalin-2; Male; Mice; Mice, Inbred C57BL; Nephritis, Interstitial; Ursodeoxycholic Acid

2017
Role of vitamin C transporters and biliverdin reductase in the dual pro-oxidant and anti-oxidant effect of biliary compounds on the placental-fetal unit in cholestasis during pregnancy.
    Toxicology and applied pharmacology, 2008, Oct-15, Volume: 232, Issue:2

    Topics: Animals; Antioxidants; Ascorbic Acid; Cell Line, Tumor; Cholestasis; Female; Humans; Male; Maternal-Fetal Exchange; Organic Anion Transporters, Sodium-Dependent; Oxidative Stress; Oxidoreductases Acting on CH-CH Group Donors; Pregnancy; Pregnancy Complications; Rats; Rats, Wistar; Reactive Oxygen Species; Ursodeoxycholic Acid

2008
Identification of UDP glycosyltransferase 3A1 as a UDP N-acetylglucosaminyltransferase.
    The Journal of biological chemistry, 2008, Dec-26, Volume: 283, Issue:52

    Topics: Amino Acid Sequence; Cell Line; Cholestasis; Cloning, Molecular; Glucose; Glucuronosyltransferase; Humans; Kidney; Kinetics; Liver; Models, Biological; Molecular Sequence Data; N-Acetylglucosaminyltransferases; Sequence Homology, Amino Acid; Uridine Diphosphate; Ursodeoxycholic Acid

2008
Ursodeoxycholic acid in neonatal hepatitis and infantile paucity of intrahepatic bile ducts: review of a historical cohort.
    Digestive diseases and sciences, 2009, Volume: 54, Issue:10

    Topics: Bile Ducts, Intrahepatic; Cholestasis; Female; Hepatitis; Humans; Infant, Newborn; Male; Retrospective Studies; Treatment Outcome; Ursodeoxycholic Acid

2009
Elevated bile acids associated with acute hepatitis A infection in the third trimester of pregnancy.
    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2009, Volume: 29, Issue:1

    Topics: Bile Acids and Salts; Cesarean Section; Cholagogues and Choleretics; Cholestasis; Diagnosis, Differential; Female; Hepatitis A; Humans; Infant, Newborn; Oligohydramnios; Pregnancy; Pregnancy Complications, Infectious; Pregnancy Trimester, Third; Ursodeoxycholic Acid; Young Adult

2009
Dysregulation of glutathione synthesis during cholestasis in mice: molecular mechanisms and therapeutic implications.
    Hepatology (Baltimore, Md.), 2009, Volume: 49, Issue:6

    Topics: Animals; Cholagogues and Choleretics; Cholestasis; Glutathione; Male; Mice; Mice, Inbred C57BL; S-Adenosylmethionine; Ursodeoxycholic Acid

2009
Influence of dominant bile duct stenoses and biliary infections on outcome in primary sclerosing cholangitis.
    Journal of hepatology, 2009, Volume: 51, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacteria; Bile; Candida; Child; Cholangitis, Sclerosing; Cholestasis; Female; Humans; Liver Transplantation; Male; Middle Aged; Prospective Studies; Ursodeoxycholic Acid

2009
[Cholestasis associated with prolonged parenteral nutrition in neonates: the role of urso-deoxycholic acid].
    Anales de pediatria (Barcelona, Spain : 2003), 2009, Volume: 70, Issue:6

    Topics: Cholagogues and Choleretics; Cholestasis; Female; Humans; Infant, Newborn; Male; Parenteral Nutrition; Retrospective Studies; Time Factors; Ursodeoxycholic Acid

2009
Pilot study for a trial of ursodeoxycholic acid and/or early delivery for obstetric cholestasis.
    BMC pregnancy and childbirth, 2009, May-16, Volume: 9

    Topics: Adolescent; Adult; Cholagogues and Choleretics; Cholestasis; Double-Blind Method; Female; Humans; Labor, Induced; Middle Aged; Pilot Projects; Pregnancy; Pregnancy Complications; Randomized Controlled Trials as Topic; Research Design; United Kingdom; Ursodeoxycholic Acid

2009
Neonatal cholestasis: differentiation of biliary atresia from neonatal hepatitis in a developing country.
    Acta paediatrica (Oslo, Norway : 1992), 2009, Volume: 98, Issue:8

    Topics: Biliary Atresia; Biopsy; Chi-Square Distribution; Cholagogues and Choleretics; Cholangiography; Cholestasis; Developing Countries; Diagnosis, Differential; Feces; Female; Hepatitis; Humans; India; Infant, Newborn; Liver; Male; Prospective Studies; Radionuclide Imaging; Sensitivity and Specificity; Ursodeoxycholic Acid

2009
Ursodeoxycholic acid for treatment of cholestasis in patients with hepatic amyloidosis.
    Vojnosanitetski pregled, 2009, Volume: 66, Issue:6

    Topics: Adult; Aged; Amyloidosis; Cholagogues and Choleretics; Cholestasis; Female; Humans; Liver Diseases; Male; Middle Aged; Ursodeoxycholic Acid

2009
Cholestasis in neonatal intensive care unit: incidence, aetiology and management.
    Acta paediatrica (Oslo, Norway : 1992), 2009, Volume: 98, Issue:11

    Topics: Bilirubin; Cholestasis; Female; Humans; Incidence; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Intensive Care Units, Neonatal; Intensive Care, Neonatal; Italy; Logistic Models; Male; Retrospective Studies; Statistics, Nonparametric; Treatment Outcome; Ursodeoxycholic Acid

2009
Ursodeoxycholic acid's role in avoiding diversionary surgery in idiopathic fibrosing pancreatitis.
    Journal of paediatrics and child health, 2009, Volume: 45, Issue:11

    Topics: Child, Preschool; Cholagogues and Choleretics; Cholestasis; Diagnosis, Differential; Female; Fibrosis; Humans; Jaundice, Obstructive; Pancreatitis; Positron-Emission Tomography; Ursodeoxycholic Acid; Victoria

2009
Induction of avian musculoaponeurotic fibrosarcoma proteins by toxic bile acid inhibits expression of glutathione synthetic enzymes and contributes to cholestatic liver injury in mice.
    Hepatology (Baltimore, Md.), 2010, Volume: 51, Issue:4

    Topics: Animals; Cell Line, Tumor; Cholestasis; Glutamate-Cysteine Ligase; Glutathione; Humans; Lithocholic Acid; MafG Transcription Factor; MafK Transcription Factor; Male; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Promoter Regions, Genetic; Repressor Proteins; Response Elements; S-Adenosylmethionine; Ursodeoxycholic Acid

2010
Atorvastatin-induced prolonged cholestasis with bile duct damage.
    Clinical drug investigation, 2010, Volume: 30, Issue:3

    Topics: Aged; Anticholesteremic Agents; Atorvastatin; Bile Ducts; Cholagogues and Choleretics; Cholangitis; Cholestasis; Dyslipidemias; Heptanoic Acids; Humans; Male; Pyrroles; Ursodeoxycholic Acid

2010
Regulation of the human bile acid UDP-glucuronosyltransferase 1A3 by the farnesoid X receptor and bile acids.
    Journal of hepatology, 2010, Volume: 52, Issue:4

    Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Gene Expression; Genes, Reporter; Genetic Variation; Glucuronosyltransferase; Hep G2 Cells; Humans; Lithocholic Acid; Luciferases; Mutagenesis, Site-Directed; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Transcriptional Activation; Ursodeoxycholic Acid; Xenobiotics

2010
In PSC with dominant bile duct stenosis, IBD is associated with an increase of carcinomas and reduced survival.
    Journal of hepatology, 2010, Volume: 53, Issue:2

    Topics: Adolescent; Adult; Aged; Bile Duct Neoplasms; Cholangitis, Sclerosing; Cholestasis; Colorectal Neoplasms; Comorbidity; Female; Follow-Up Studies; Gallbladder Neoplasms; Humans; Incidence; Inflammatory Bowel Diseases; Kaplan-Meier Estimate; Liver Transplantation; Longitudinal Studies; Male; Middle Aged; Prospective Studies; Survival Rate; Ursodeoxycholic Acid; Young Adult

2010
Conjugation is essential for the anticholestatic effect of NorUrsodeoxycholic acid in taurolithocholic acid-induced cholestasis in rat liver.
    Hepatology (Baltimore, Md.), 2010, Volume: 52, Issue:5

    Topics: Animals; Apoptosis; Bile; Bile Acids and Salts; Carcinoma, Hepatocellular; Cholangitis; Cholestasis; Chromatography, Gas; Hepatoblastoma; Humans; Liver; Liver Diseases; Liver Neoplasms; Male; Mice; Rats; Rats, Sprague-Dawley; Taurine; Taurolithocholic Acid; Ursodeoxycholic Acid

2010
Pruritus of unknown origin and elevated total serum bile acid levels in patients without clinically apparent liver disease.
    Journal of gastroenterology and hepatology, 2011, Volume: 26, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Asymptomatic Diseases; Austria; Bile Acids and Salts; Biomarkers; Cholagogues and Choleretics; Cholestasis; Cholestyramine Resin; Chronic Disease; Female; Humans; Male; Middle Aged; Pruritus; Retrospective Studies; Risk Factors; Treatment Outcome; Up-Regulation; Ursodeoxycholic Acid

2011
Stevens-Johnson syndrome and cholestatic hepatitis induced by acute Epstein-Barr virus infection.
    European journal of gastroenterology & hepatology, 2011, Volume: 23, Issue:3

    Topics: Amoxicillin; Anti-Bacterial Agents; Antiviral Agents; Child, Preschool; Cholagogues and Choleretics; Cholestasis; Clavulanic Acid; Epstein-Barr Virus Infections; Female; Hepatitis; Humans; Immunoglobulins; Steroids; Stevens-Johnson Syndrome; Ursodeoxycholic Acid

2011
Delayed postnatal presentation of biliary atresia in 2 premature neonates.
    Journal of pediatric gastroenterology and nutrition, 2011, Volume: 52, Issue:4

    Topics: Bile Ducts; Biliary Atresia; Bilirubin; Child Development; Cholagogues and Choleretics; Cholestasis; Color; Feces; Female; Humans; Infant, Newborn; Infant, Premature; Infant, Premature, Diseases; Jaundice, Neonatal; Portoenterostomy, Hepatic; Treatment Outcome; Ultrasonography; Ursodeoxycholic Acid

2011
Cholestatic hepatitis related to amoxicillin.
    Drug and chemical toxicology, 2011, Volume: 34, Issue:4

    Topics: Adult; Amoxicillin; Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Cholagogues and Choleretics; Cholestasis; Female; Humans; Liver Function Tests; Treatment Outcome; Ursodeoxycholic Acid

2011
[No complaints, but constantly elevated cholestatic serum liver tests].
    Praxis, 2011, Jul-06, Volume: 100, Issue:14

    Topics: Aged; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Autoantibodies; Cholangitis, Sclerosing; Cholestasis; Diagnosis, Differential; Female; gamma-Glutamyltransferase; Humans; Liver Cirrhosis, Biliary; Liver Function Tests; Mitochondria, Liver; Ultrasonography; Ursodeoxycholic Acid

2011
Two-year experience of obstetric cholestasis: outcome and management.
    Clinical and experimental obstetrics & gynecology, 2011, Volume: 38, Issue:3

    Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Cholagogues and Choleretics; Cholestasis; Female; Fetal Membranes, Premature Rupture; Humans; Infant, Newborn; Intensive Care Units, Neonatal; Patient Admission; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Respiratory Distress Syndrome, Newborn; Retrospective Studies; Ursodeoxycholic Acid

2011
A contemporary analysis of parenteral nutrition-associated liver disease in surgical infants.
    Journal of pediatric surgery, 2011, Volume: 46, Issue:10

    Topics: Cholestasis; Diagnosis-Related Groups; Female; Humans; Hyperbilirubinemia; Incidence; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature, Diseases; Logistic Models; Male; Nutritional Support; Parenteral Nutrition; Postoperative Complications; Prognosis; Retrospective Studies; Ursodeoxycholic Acid

2011
Prurigo nodularis as the first manifestation of a chronic autoimmune cholestatic hepatitis.
    International journal of dermatology, 2011, Volume: 50, Issue:12

    Topics: Alkaline Phosphatase; Antibodies, Antinuclear; Azathioprine; Cholestasis; Cyclosporine; Dermatologic Agents; Female; gamma-Glutamyltransferase; Hepatitis, Autoimmune; Humans; Middle Aged; Prurigo; Ursodeoxycholic Acid

2011
Neonatal jaundice.
    Clinics and research in hepatology and gastroenterology, 2012, Volume: 36, Issue:3

    Topics: Biliary Atresia; Bilirubin; Cholagogues and Choleretics; Cholestasis; Diagnosis, Differential; Diagnostic Techniques, Digestive System; Diet; Energy Intake; Hepatitis; Hepatomegaly; Humans; Incidence; Infant, Newborn; Jaundice, Neonatal; Prognosis; Splenomegaly; Syndrome; Ursodeoxycholic Acid; Vitamins

2012
Does ursodeoxycholic acid exert a protective effect on liver grafts in orthotopic liver transplantation?
    Digestion, 2012, Volume: 86, Issue:3

    Topics: Cholagogues and Choleretics; Cholestasis; Humans; Liver Transplantation; Postoperative Care; Transplantation, Homologous; Ursodeoxycholic Acid

2012
Ursodeoxycholic acid: increased mortality.
    Prescrire international, 2012, Volume: 21, Issue:130

    Topics: Cholagogues and Choleretics; Cholestasis; Chronic Disease; Digestive System Diseases; Drug Administration Schedule; Evidence-Based Medicine; Humans; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome; Ursodeoxycholic Acid

2012
Low phospholipid-associated cholestasis and cholelithiasis.
    Clinics and research in hepatology and gastroenterology, 2012, Volume: 36 Suppl 1

    Topics: Age Distribution; ATP Binding Cassette Transporter, Subfamily B; Cholagogues and Choleretics; Cholelithiasis; Cholestasis; Diagnosis, Differential; Female; Genotype; Humans; Mutation; Phenotype; Phospholipids; Pregnancy; Pregnancy Complications; Risk Factors; Syndrome; Treatment Outcome; Ursodeoxycholic Acid

2012
Artemisia capillaris extract protects against bile duct ligation-induced liver fibrosis in rats.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2013, Volume: 65, Issue:6

    Topics: Animals; Antioxidants; Artemisia; Cholagogues and Choleretics; Cholestasis; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Liver Cirrhosis; Liver Function Tests; Male; Rats; Rats, Sprague-Dawley; Ursodeoxycholic Acid

2013
Differential effects of norUDCA and UDCA in obstructive cholestasis in mice.
    Journal of hepatology, 2013, Volume: 58, Issue:6

    Topics: Adenosine Triphosphate; Animals; Bicarbonates; Cholestasis; Humans; Male; Mice; Mice, Inbred C57BL; Ursodeoxycholic Acid

2013
Prevention and treatment of intestinal failure-associated liver disease in children.
    Seminars in liver disease, 2012, Volume: 32, Issue:4

    Topics: Cholagogues and Choleretics; Cholestasis; Fat Emulsions, Intravenous; Fatty Liver; Humans; Intestinal Diseases; Liver Cirrhosis; Liver Diseases; Parenteral Nutrition; Ursodeoxycholic Acid

2012
Effect of Ursodeoxycholic Acid on the Expression of the Hepatocellular Bile Acid Transporters (Ntcp and bsep) in Rats With Estrogen-Induced Cholestasis.
    Journal of pediatric gastroenterology and nutrition, 2002, Volume: 35, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Biological Transport, Active; Carrier Proteins; Cholestasis; Estradiol Congeners; Ethinyl Estradiol; Glutathione; Hydroxysteroid Dehydrogenases; Immunoblotting; Male; Membrane Glycoproteins; Membrane Proteins; Membrane Transport Proteins; Organic Anion Transporters, Sodium-Dependent; Rats; Rats, Sprague-Dawley; RNA, Messenger; Symporters; Ursodeoxycholic Acid

2002
[Clinical analysis of 22 patients with primary biliary cirrhosis].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2002, Volume: 10, Issue:5

    Topics: Alkaline Phosphatase; Bilirubin; Cholestasis; Female; Hepatomegaly; Humans; Liver Cirrhosis, Biliary; Liver Function Tests; Male; Middle Aged; Ursodeoxycholic Acid

2002
Colestimide: the efficacy of a novel anion-exchange resin in cholestatic disorders.
    Journal of gastroenterology and hepatology, 2002, Volume: 17, Issue:11

    Topics: Anion Exchange Resins; Antipruritics; Bile Acids and Salts; Cholagogues and Choleretics; Cholestasis; Cholestyramine Resin; Cholic Acid; Epichlorohydrin; Humans; Imidazoles; Pruritus; Resins, Synthetic; Ursodeoxycholic Acid

2002
Mitochondrially mediated synergistic cell killing by bile acids.
    Biochimica et biophysica acta, 2003, Jan-20, Volume: 1637, Issue:1

    Topics: Adenine Nucleotides; Animals; Bile Acids and Salts; Cell Survival; Chenodeoxycholic Acid; Cholestasis; Drug Synergism; Hepatocytes; Ion Channels; Male; Mitochondria; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Rats; Rats, Sprague-Dawley; Rhodamines; Time Factors; Ursodeoxycholic Acid

2003
Ursodeoxycholic acid in the treatment of cholestasis and hyperbilirubinemia in pediatric intensive care unit patients.
    Southern medical journal, 2002, Volume: 95, Issue:11

    Topics: Adolescent; Child; Cholagogues and Choleretics; Cholestasis; Female; Humans; Hyperbilirubinemia; Infant; Intensive Care Units, Pediatric; Male; Retrospective Studies; Treatment Outcome; Ursodeoxycholic Acid

2002
Effect of ursodeoxycholic acid on the impairment induced by maternal cholestasis in the rat placenta-maternal liver tandem excretory pathway.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 305, Issue:2

    Topics: Animals; Antipyrine; Cell Membrane; Cholestasis; DNA Primers; Female; Gene Expression; Glycocholic Acid; Kinetics; Liver; Maternal-Fetal Exchange; Placenta; Pregnancy; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Ursodeoxycholic Acid

2003
Ursodeoxycholate reduces ethinylestradiol glucuronidation in the rat: role in prevention of estrogen-induced cholestasis.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 306, Issue:1

    Topics: Animals; Bile; Bile Acids and Salts; Cholagogues and Choleretics; Cholestasis; Estrogens; Ethinyl Estradiol; Hepatocytes; Kinetics; Lipids; Liver; Male; Microsomes, Liver; Rats; Rats, Wistar; Taurochenodeoxycholic Acid; Ursodeoxycholic Acid

2003
Regulation of rat organic anion transporters in bile salt-induced cholestatic hepatitis: effect of ursodeoxycholate.
    Hepatology (Baltimore, Md.), 2003, Volume: 38, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; Bile Acids and Salts; Blotting, Northern; Carrier Proteins; Cholagogues and Choleretics; Cholestasis; Cholic Acid; Fluorescent Antibody Technique; Gene Expression; Hepatitis; Liver; Male; Membrane Transport Proteins; Organic Anion Transport Protein 1; Organic Anion Transporters; Organic Anion Transporters, Sodium-Dependent; Organic Anion Transporters, Sodium-Independent; Organic Cation Transport Proteins; Rats; Rats, Wistar; RNA, Messenger; Solute Carrier Organic Anion Transporter Family Member 1B3; Symporters; Ursodeoxycholic Acid

2003
Inappropriate ileal conservation of bile acids in cholestatic liver disease: homeostasis gone awry.
    Gut, 2003, Volume: 52, Issue:9

    Topics: Bile Acids and Salts; Cholagogues and Choleretics; Cholestasis; Homeostasis; Humans; Ileum; Ursodeoxycholic Acid

2003
Obstetric cholestasis with elevated gamma glutamyl transpeptidase: incidence, presentation and treatment.
    Journal of gastroenterology and hepatology, 2003, Volume: 18, Issue:11

    Topics: Alanine Transaminase; Cholagogues and Choleretics; Cholestasis; Female; gamma-Glutamyltransferase; Humans; Incidence; Liver Function Tests; Pregnancy; Pregnancy Complications; Treatment Outcome; Ursodeoxycholic Acid

2003
An unusual combination of relapsing and cholestatic hepatitis A in childhood.
    Yonsei medical journal, 2003, Oct-30, Volume: 44, Issue:5

    Topics: Adolescent; Alanine Transaminase; Aspartate Aminotransferases; Cholestasis; Hepatitis A; Humans; Male; Ursodeoxycholic Acid

2003
Extreme short bowel syndrome in a full-term neonate--a case report.
    Journal of pediatric surgery, 2003, Volume: 38, Issue:11

    Topics: Anastomosis, Surgical; Breast Feeding; Cholagogues and Choleretics; Cholestasis; Diarrhea, Infantile; Humans; Infant, Newborn; Intestinal Volvulus; Intestines; Liver Function Tests; Male; Necrosis; Parenteral Nutrition; Short Bowel Syndrome; Steatorrhea; Ursodeoxycholic Acid

2003
Hepatoprotection by the farnesoid X receptor agonist GW4064 in rat models of intra- and extrahepatic cholestasis.
    The Journal of clinical investigation, 2003, Volume: 112, Issue:11

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Carrier Proteins; Cholestasis; Cytoprotection; DNA-Binding Proteins; Isocyanates; Isoxazoles; Male; Membrane Transport Proteins; Naphthalenes; Organic Anion Transporters, Sodium-Dependent; Organic Anion Transporters, Sodium-Independent; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Steroid 12-alpha-Hydroxylase; Symporters; Taurine; Transcription Factors; Ursodeoxycholic Acid

2003
Ursodeoxycholic acid protects against secondary biliary cirrhosis in rats by preventing mitochondrial oxidative stress.
    Hepatology (Baltimore, Md.), 2004, Volume: 39, Issue:3

    Topics: Animals; Cardiolipins; Cholestasis; Chronic Disease; Cystathionine gamma-Lyase; Glutamate-Cysteine Ligase; Glutathione; Hepatocytes; Liver; Liver Cirrhosis, Biliary; Male; Membrane Potentials; Mitochondria; Oxidation-Reduction; Oxidative Stress; Peroxides; Rats; Rats, Wistar; Ursodeoxycholic Acid

2004
Ursodeoxycholic acid for terbinafine-induced toxic hepatitis.
    The Annals of pharmacotherapy, 2004, Volume: 38, Issue:6

    Topics: Antifungal Agents; Chemical and Drug Induced Liver Injury; Cholagogues and Choleretics; Cholestasis; Female; Humans; Middle Aged; Naphthalenes; Onychomycosis; Terbinafine; Ursodeoxycholic Acid

2004
Ursodeoxycholic acid (UDCA) therapy in very-low-birth-weight infants with parenteral nutrition-associated cholestasis.
    The Journal of pediatrics, 2004, Volume: 145, Issue:3

    Topics: Bilirubin; Birth Weight; Case-Control Studies; Cholestasis; Female; Gestational Age; Humans; Infant; Infant, Newborn; Infant, Very Low Birth Weight; Male; Parenteral Nutrition; Retrospective Studies; Treatment Outcome; Ursodeoxycholic Acid

2004
Long-term effect of treating pregnant rats with ursodeoxycholic acid on the congenital impairment of bile secretion induced in the pups by maternal cholestasis.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 312, Issue:2

    Topics: Animals; Animals, Newborn; Bile; Bile Acids and Salts; Bile Canaliculi; Carrier Proteins; Cell Membrane; Cholagogues and Choleretics; Cholestasis; Cholesterol; DNA Primers; Female; Gene Expression Regulation, Enzymologic; Membrane Fluidity; Microscopy, Electron, Transmission; Phospholipids; Pregnancy; Pregnancy, Animal; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA; Ursodeoxycholic Acid

2005
Prevention of Mrp2 activity impairment in ethinylestradiol-induced cholestasis by ursodeoxycholate in the rat.
    Drug metabolism and disposition: the biological fate of chemicals, 2005, Volume: 33, Issue:7

    Topics: Animals; Bile; Cholestasis; Ethinyl Estradiol; Hepatocytes; Male; Mitochondrial Proteins; Protein Transport; Rats; Rats, Wistar; Ribosomal Proteins; Saccharomyces cerevisiae Proteins; Ursodeoxycholic Acid

2005
Oxidative stress and apoptosis in fetal rat liver induced by maternal cholestasis. Protective effect of ursodeoxycholic acid.
    Journal of hepatology, 2005, Volume: 43, Issue:2

    Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis; bcl-2-Associated X Protein; Bile Acids and Salts; Biomarkers; Caspase 3; Caspases; Cholagogues and Choleretics; Cholestasis; Disease Models, Animal; Enzyme Precursors; Female; Liver; Maternal-Fetal Exchange; Oxidative Stress; Pregnancy; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Ursodeoxycholic Acid

2005
Maternal cholestasis induces placental oxidative stress and apoptosis. Protective effect of ursodeoxycholic acid.
    Placenta, 2006, Volume: 27, Issue:1

    Topics: Animals; Apoptosis; Cell Nucleus; Cholestasis; Female; Lipid Peroxidation; Oxidative Stress; Placenta; Pregnancy; Pregnancy Complications; Rats; Rats, Wistar; Ursodeoxycholic Acid

2006
Ursodeoxycholic acid therapy for intractable total parenteral nutrition-associated cholestasis in surgical very low birth weight infants.
    Singapore medical journal, 2006, Volume: 47, Issue:2

    Topics: Administration, Oral; Cholagogues and Choleretics; Cholestasis; Female; Humans; Infant; Infant, Newborn; Infant, Very Low Birth Weight; Male; Parenteral Nutrition, Total; Retrospective Studies; Ursodeoxycholic Acid

2006
Ca2+-dependent cytoprotective effects of ursodeoxycholic and tauroursodeoxycholic acid on the biliary epithelium in a rat model of cholestasis and loss of bile ducts.
    The American journal of pathology, 2006, Volume: 168, Issue:2

    Topics: Animals; Apoptosis; Bile Ducts; Calcium; Cell Proliferation; Cholestasis; Cytoprotection; Disease Models, Animal; Egtazic Acid; Enzyme Activation; Epithelium; Ligation; Male; Mitogen-Activated Protein Kinase Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase C-alpha; Rats; Rats, Inbred F344; Signal Transduction; Taurochenodeoxycholic Acid; Ursodeoxycholic Acid; Vagotomy

2006
3alpha-6alpha-Dihydroxy-7alpha-fluoro-5beta-cholanoate (UPF-680), physicochemical and physiological properties of a new fluorinated bile acid that prevents 17alpha-ethynyl-estradiol-induced cholestasis in rats.
    Toxicology and applied pharmacology, 2006, Jul-15, Volume: 214, Issue:2

    Topics: Animals; Bile; Bile Ducts; Cholanes; Cholestasis; Cholesterol 7-alpha-Hydroxylase; Chromatography, High Pressure Liquid; Deoxycholic Acid; Dose-Response Relationship, Drug; Ethinyl Estradiol; Gas Chromatography-Mass Spectrometry; Male; Micelles; Molecular Structure; Phospholipids; Rats; Rats, Sprague-Dawley; RNA, Messenger; Steroid 12-alpha-Hydroxylase; Steroids, Fluorinated; Ursodeoxycholic Acid

2006
Effect of maternal cholestasis and treatment with ursodeoxycholic acid on the expression of genes involved in the secretion of biliary lipids by the neonatal rat liver.
    Life sciences, 2006, Aug-01, Volume: 79, Issue:10

    Topics: Animals; Animals, Newborn; Bile Acids and Salts; Carrier Proteins; Cholestasis; Female; Fetus; Gene Expression Regulation; Liver; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Ursodeoxycholic Acid

2006
Early treatment with ursodeoxycholic acid for cholestasis in children on parenteral nutrition because of primary intestinal failure.
    Alimentary pharmacology & therapeutics, 2006, Jul-15, Volume: 24, Issue:2

    Topics: Cholagogues and Choleretics; Cholestasis; Humans; Infant; Infant, Newborn; Intestinal Diseases; Parenteral Nutrition; Treatment Outcome; Ursodeoxycholic Acid

2006
Obstetric cholestasis characterized by extremely elevated serum transaminases.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2007, Volume: 98, Issue:2

    Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Cholagogues and Choleretics; Cholestasis; Female; Humans; Pregnancy; Pregnancy Complications; Pruritus; Ursodeoxycholic Acid

2007
Hypoxia-induced changes in the expression of rat hepatobiliary transporter genes.
    American journal of physiology. Gastrointestinal and liver physiology, 2007, Volume: 293, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Ducts; Cells, Cultured; Cholestasis; Cystic Fibrosis Transmembrane Conductance Regulator; Gene Expression Regulation; Hypoxia; Ischemia; Liver; Male; Organic Anion Transporters; Organic Anion Transporters, Sodium-Dependent; Rats; Rats, Wistar; Symporters; Ursodeoxycholic Acid; Vascular Endothelial Growth Factor A

2007
Atorvastatin in patients with primary biliary cirrhosis and incomplete biochemical response to ursodeoxycholic acid.
    Hepatology (Baltimore, Md.), 2007, Volume: 46, Issue:3

    Topics: Adult; Anticholesteremic Agents; Atorvastatin; Biomarkers; Cholagogues and Choleretics; Cholestasis; Cholesterol; Female; Heptanoic Acids; Humans; Lipoproteins, LDL; Liver Cirrhosis, Biliary; Male; Middle Aged; Prospective Studies; Pyrroles; Single-Blind Method; Transaminases; Ursodeoxycholic Acid

2007
Anabolic-androgenic steroids and liver injury.
    Liver international : official journal of the International Association for the Study of the Liver, 2008, Volume: 28, Issue:2

    Topics: Adult; Anabolic Agents; Androgens; Chemical and Drug Induced Liver Injury; Cholestasis; Hepatomegaly; Humans; Liver Diseases; Male; Treatment Outcome; Ursodeoxycholic Acid

2008
Prolonged cholestasis following successful removal of common bile duct stones: beware patients on estrogen therapy.
    World journal of gastroenterology, 2007, Dec-14, Volume: 13, Issue:46

    Topics: Adrenal Cortex Hormones; Adult; Aged; Cholagogues and Choleretics; Cholangiopancreatography, Endoscopic Retrograde; Cholestasis; Estrogen Replacement Therapy; Estrogens; Female; Gallstones; Humans; Postoperative Complications; Ursodeoxycholic Acid

2007
Glycoursodeoxycholate is as effective as tauroursodeoxycholate in preventing the taurocholate-induced cholestasis in the rat.
    Research communications in chemical pathology and pharmacology, 1983, Volume: 42, Issue:3

    Topics: Animals; Bile; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Deoxycholic Acid; Drug Evaluation, Preclinical; Rats; Secretory Rate; Taurochenodeoxycholic Acid; Taurocholic Acid; Ursodeoxycholic Acid

1983
Treatment of parenteral nutrition-associated cholestasis with cholecystokinin-octapeptide.
    Journal of pediatric surgery, 1995, Volume: 30, Issue:7

    Topics: Abdomen; Abdominal Pain; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Cardiac Surgical Procedures; Cholestasis; Eating; Humans; Hyperbilirubinemia; Infant, Newborn; Injections, Intramuscular; Injections, Intravenous; Liver Failure; Parenteral Nutrition, Total; Sincalide; Survival Rate; Ursodeoxycholic Acid

1995
Enhanced biliary excretion of canalicular membrane enzymes in ethynylestradiol-induced cholestasis. Effects of ursodeoxycholic acid administration.
    Biochemical pharmacology, 1995, Oct-12, Volume: 50, Issue:8

    Topics: Alkaline Phosphatase; Animals; Bile; Bile Acids and Salts; Bile Canaliculi; Cell Fractionation; Cell Membrane; Cholestasis; Ethinyl Estradiol; gamma-Glutamyltransferase; Liver; Male; Rats; Rats, Wistar; Secretory Rate; Ursodeoxycholic Acid

1995
Fetal mortality associated with cholestasis of pregnancy and the potential benefit of therapy with ursodeoxycholic acid.
    Gut, 1995, Volume: 37, Issue:4

    Topics: Adult; Cholestasis; Female; Fetal Death; Humans; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Third; Pruritus; Ursodeoxycholic Acid

1995
Lipoprotein abnormalities in two children with minimal biliary excretion.
    Journal of pediatric gastroenterology and nutrition, 1995, Volume: 20, Issue:4

    Topics: Alagille Syndrome; Bile Acids and Salts; Bile Duct Diseases; Child, Preschool; Cholestasis; Cholesterol; Humans; Infant; Lipid Metabolism; Lipids; Lipoprotein-X; Lipoproteins; Male; Ursodeoxycholic Acid

1995
Effect of cholestasis and bile acids on interferon-induced 2',5'-adenylate synthetase and NK cell activities.
    Gastroenterology, 1995, Volume: 108, Issue:4

    Topics: 2',5'-Oligoadenylate Synthetase; Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Enzyme Induction; Humans; Interferon-alpha; Killer Cells, Natural; Lymphocytes; Male; Rats; Rats, Wistar; Ursodeoxycholic Acid

1995
Ursodeoxycholic acid for the treatment of flucloxacillin-associated cholestasis.
    Journal of hepatology, 1995, Volume: 22, Issue:1

    Topics: Aged; Cholestasis; Floxacillin; Humans; Male; Middle Aged; Ursodeoxycholic Acid

1995
Effects of ursodeoxycholic acid on hemodynamic and renal function abnormalities induced by obstructive jaundice in rats.
    Renal failure, 1995, Volume: 17, Issue:1

    Topics: Analysis of Variance; Animals; Cholestasis; Drug Evaluation, Preclinical; Hemodynamics; Hypertension, Portal; Kidney; Male; Random Allocation; Rats; Rats, Wistar; Ursodeoxycholic Acid

1995
[Benign biliary stricture treated successfully by implantable injection port--report of a case].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1994, Volume: 91, Issue:12

    Topics: Cholestasis; Constriction, Pathologic; Drainage; Humans; Infusion Pumps, Implantable; Male; Middle Aged; Ursodeoxycholic Acid

1994
[Nodular regenerative hyperplasia of the liver and Turner syndrome].
    Gastroenterologie clinique et biologique, 1994, Volume: 18, Issue:10

    Topics: Adult; Cholestasis; Female; Humans; Hyperplasia; Liver; Turner Syndrome; Ursodeoxycholic Acid

1994
Preventing biliary stent occlusion.
    Lancet (London, England), 1994, Oct-15, Volume: 344, Issue:8929

    Topics: Bacterial Infections; Cholestasis; Drug Therapy, Combination; Humans; Norfloxacin; Stents; Ursodeoxycholic Acid

1994
Is ursodeoxycholic acid an effective therapy for total parenteral nutrition-related liver disease?
    Journal of hepatology, 1994, Volume: 20, Issue:2

    Topics: Adult; Aged; Cholestasis; Female; Humans; Male; Middle Aged; Parenteral Nutrition, Total; Short Bowel Syndrome; Ursodeoxycholic Acid

1994
A 20-year-old woman with portal hypertension and a cholestatic syndrome.
    Hepatology (Baltimore, Md.), 1994, Volume: 20, Issue:2

    Topics: Adult; Biopsy; Cholestasis; Diagnosis, Differential; Female; Humans; Hypertension, Portal; Liver; Liver Cirrhosis; Prognosis; Ursodeoxycholic Acid

1994
Variable effect of ursodeoxycholic acid on cyclosporin absorption after orthotopic liver transplantation.
    Transplant international : official journal of the European Society for Organ Transplantation, 1994, Volume: 7, Issue:3

    Topics: Absorption; Adolescent; Adult; Aged; Biological Availability; Cholestasis; Cyclosporine; Female; Graft Rejection; Half-Life; Humans; Liver; Liver Transplantation; Male; Middle Aged; Transplantation, Homologous; Ursodeoxycholic Acid

1994
Ursodeoxycholic acid improves ethinyl estradiol-induced cholestasis in the rat.
    European journal of clinical investigation, 1993, Volume: 23, Issue:12

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Bile; Bile Acids and Salts; Cholestasis; Ethinyl Estradiol; Female; Rats; Rats, Sprague-Dawley; Sucrose; Ursodeoxycholic Acid

1993
Diminution of an acute cyclosporin-induced cholestasis by tauroursodeoxycholate in the rat.
    Transplantation, 1993, Volume: 56, Issue:3

    Topics: Animals; Bile Acids and Salts; Cholagogues and Choleretics; Cholestasis; Cyclosporine; Male; Rats; Rats, Sprague-Dawley; Solutions; Taurine; Ursodeoxycholic Acid; Viscosity

1993
Taurine conjugate of ursodeoxycholate plays a major role in the hepatoprotective effect against cholestasis induced by taurochenodeoxycholate in rats.
    Liver, 1993, Volume: 13, Issue:5

    Topics: Alkaline Phosphatase; Animals; Bile; Bile Acids and Salts; Cholestasis; L-Lactate Dehydrogenase; Liver; Male; Rats; Rats, Wistar; Taurochenodeoxycholic Acid; Ursodeoxycholic Acid

1993
Protection against alpha-naphthylisothiocyanate-induced acute cholestasis in mice by a novel taurine conjugate of ursodeoxycholate (UR-906).
    Japanese journal of pharmacology, 1993, Volume: 63, Issue:1

    Topics: 1-Naphthylisothiocyanate; Administration, Oral; Animals; Bile Acids and Salts; Bilirubin; Biomarkers; Cholestasis; L-Lactate Dehydrogenase; Liver; Male; Mice; Taurine; Ursodeoxycholic Acid

1993
Effect of ursodeoxycholic acid administration on bile duct proliferation and cholestasis in bile duct ligated rat.
    Digestive diseases and sciences, 1993, Volume: 38, Issue:7

    Topics: Animals; Bile Ducts; Cell Division; Cholestasis; Common Bile Duct; Drug Evaluation, Preclinical; Ligation; Liver; Male; Rats; Rats, Sprague-Dawley; Time Factors; Ursodeoxycholic Acid

1993
Lithocholate-3-O-glucuronide-induced cholestasis. A study with congenital hyperbilirubinemic rats and effects of ursodeoxycholate conjugates.
    Digestive diseases and sciences, 1993, Volume: 38, Issue:8

    Topics: Animals; Bile; Cholestasis; Glucuronates; Hyperbilirubinemia, Hereditary; Lithocholic Acid; Liver; Male; Rats; Rats, Sprague-Dawley; Taurochenodeoxycholic Acid; Ursodeoxycholic Acid

1993
[Experimental study on the effects of endotoxemia as a retardation-factor influencing on the decrease of serum bilirubin after the relief of obstructive jaundice].
    Nihon Geka Gakkai zasshi, 1993, Volume: 94, Issue:8

    Topics: Animals; Bilirubin; Cholestasis; Endotoxins; Male; Methylprednisolone; Rats; Rats, Inbred Strains; Ursodeoxycholic Acid

1993
Estradiol-17 beta-glucuronide-induced cholestasis. Effects of ursodeoxycholate-3-O-glucuronide and 3,7-disulfate.
    Journal of hepatology, 1993, Volume: 17, Issue:2

    Topics: Animals; Bile; Cholagogues and Choleretics; Cholestasis; Estradiol; Hyperbilirubinemia, Hereditary; Isomerism; Male; Rats; Rats, Mutant Strains; Taurochenodeoxycholic Acid; Ursodeoxycholic Acid

1993
[Results of 4 years of gallstone lithotripsy].
    Nederlands tijdschrift voor geneeskunde, 1993, Apr-10, Volume: 137, Issue:15

    Topics: Adult; Aged; Aged, 80 and over; Chenodeoxycholic Acid; Cholecystectomy; Cholelithiasis; Cholestasis; Colic; Female; Humans; Lithotripsy; Male; Middle Aged; Pancreatitis; Recurrence; Retrospective Studies; Ursodeoxycholic Acid

1993
Hepatic lymph nodes as follow-up factor in primary biliary cirrhosis. An ultrasound study.
    Scandinavian journal of gastroenterology, 1995, Volume: 30, Issue:10

    Topics: Adult; Aged; Cholestasis; Female; Follow-Up Studies; Humans; Liver; Liver Cirrhosis, Biliary; Lymph Nodes; Male; Middle Aged; Ultrasonography; Ursodeoxycholic Acid

1995
Biliary secretion of bile acids and lipids in primary sclerosing cholangitis. Influence of cholestasis and effect of ursodeoxycholic acid treatment.
    Journal of hepatology, 1995, Volume: 23, Issue:3

    Topics: Adolescent; Adult; Bile; Bile Acids and Salts; Cholagogues and Choleretics; Cholangitis, Sclerosing; Cholestasis; Female; Humans; Lipid Metabolism; Male; Middle Aged; Ursodeoxycholic Acid

1995
Different protective effects of tauroursodeoxycholate, ursodeoxycholate, and 23-methyl-ursodeoxycholate against taurolithocholate-induced cholestasis.
    Digestive diseases and sciences, 1996, Volume: 41, Issue:2

    Topics: Animals; Cholelithiasis; Cholestasis; Isomerism; Male; Rats; Rats, Sprague-Dawley; Taurine; Taurolithocholic Acid; Ursodeoxycholic Acid

1996
Should we treat cholestatic liver disease with cholesterol synthesis inhibitors?
    The American journal of gastroenterology, 1996, Volume: 91, Issue:2

    Topics: Anticholesteremic Agents; Cholagogues and Choleretics; Cholestasis; Humans; Liver Cirrhosis, Biliary; Liver Diseases; Ursodeoxycholic Acid

1996
Delta 4-3-oxosteroid 5 beta-reductase deficiency: failure of ursodeoxycholic acid treatment and response to chenodeoxycholic acid plus cholic acid.
    Gut, 1996, Volume: 38, Issue:4

    Topics: Bile Acids and Salts; Chenodeoxycholic Acid; Cholagogues and Choleretics; Cholestasis; Cholic Acid; Cholic Acids; Female; Humans; Infant, Newborn; Oxidoreductases; Ursodeoxycholic Acid

1996
Cyclosporin A-mediated cholestasis in patients with chronic hepatitis after heart transplantation.
    European journal of gastroenterology & hepatology, 1996, Volume: 8, Issue:3

    Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Bile Acids and Salts; Bilirubin; Chenodeoxycholic Acid; Cholestasis; Cholic Acid; Cholic Acids; Chromatography, High Pressure Liquid; Cyclosporine; Fasting; Female; Glycocholic Acid; Heart Transplantation; Hepatitis, Chronic; Humans; Immunosuppressive Agents; Lithocholic Acid; Male; Middle Aged; Spectrophotometry, Ultraviolet; Taurocholic Acid; Ursodeoxycholic Acid

1996
Ursodeoxycholic acid for treatment of cholestasis in children on long-term total parenteral nutrition: a pilot study.
    Gastroenterology, 1996, Volume: 111, Issue:3

    Topics: Alanine Transaminase; Alkaline Phosphatase; Bilirubin; Cholestasis; gamma-Glutamyltransferase; Gastrointestinal Agents; Humans; Infant; Male; Parenteral Nutrition, Total; Pilot Projects; Time Factors; Treatment Outcome; Ursodeoxycholic Acid

1996
Hepatitis and cholestasis in a middle-aged woman.
    Hepatology (Baltimore, Md.), 1996, Volume: 24, Issue:3

    Topics: Adult; Azathioprine; Cholestasis; Drug Therapy, Combination; Female; Hepatitis; Humans; Prednisone; Ursodeoxycholic Acid

1996
Intravenous ursodeoxycholic acid reduces cholestasis in parenterally fed newborn piglets.
    Gastroenterology, 1996, Volume: 111, Issue:4

    Topics: Animals; Animals, Newborn; Bile; Cholestasis; Injections, Intravenous; Lipids; Parenteral Nutrition, Total; Sodium-Potassium-Exchanging ATPase; Swine; Ursodeoxycholic Acid

1996
Post-infantile giant cell hepatitis in patients with primary sclerosing cholangitis and autoimmune hepatitis.
    Liver, 1996, Volume: 16, Issue:4

    Topics: Adrenal Cortex Hormones; Adult; Alanine Transaminase; Aspartate Aminotransferases; Autoimmunity; Bilirubin; Cholangiopancreatography, Endoscopic Retrograde; Cholangitis; Cholestasis; Female; Giant Cells; Hepatitis; Histocytochemistry; HLA Antigens; Humans; Immunosuppressive Agents; Male; Serology; Ursodeoxycholic Acid

1996
Bile acid concentrations in human and rat liver tissue and in hepatocyte nuclei.
    Gastroenterology, 1997, Volume: 112, Issue:1

    Topics: Adult; Animals; Bile Acids and Salts; Cell Nucleus; Cholestasis; Humans; Liver; Male; Middle Aged; Rats; Rats, Sprague-Dawley; Taurochenodeoxycholic Acid; Ursodeoxycholic Acid

1997
Protective effect of the intravenous administration of ursodeoxycholic acid against endotoxemia in rats with obstructive jaundice.
    Surgery today, 1997, Volume: 27, Issue:2

    Topics: Analysis of Variance; Animals; Bile Acids and Salts; Cholestasis; Endotoxemia; Injections, Intravenous; Lipopolysaccharides; Male; Rats; Rats, Wistar; Ursodeoxycholic Acid

1997
Urinary 1 beta-hydroxyursodeoxycholic acid during ursodeoxycholic acid therapy.
    Journal of gastroenterology, 1996, Volume: 31, Issue:6

    Topics: Cholagogues and Choleretics; Cholestasis; Deoxycholic Acid; Gas Chromatography-Mass Spectrometry; Humans; Ursodeoxycholic Acid

1996
Ursodeoxycholic acid in the management of prolonged cholestasis of acute hepatitis B.
    Journal of clinical gastroenterology, 1997, Volume: 24, Issue:2

    Topics: Acute Disease; Adult; Cholagogues and Choleretics; Cholestasis; Hepatitis B; Humans; Male; Ursodeoxycholic Acid

1997
Nonsyndromic paucity of interlobular bile ducts: clinical and laboratory findings of 10 cases.
    Journal of pediatric gastroenterology and nutrition, 1997, Volume: 24, Issue:1

    Topics: Bile Ducts; Biopsy; Child, Preschool; Cholestasis; Cholestyramine Resin; Consanguinity; Female; Humans; Infant; Jaundice; Liver; Liver Function Tests; Liver Transplantation; Male; Phenobarbital; Prednisolone; Prognosis; Pruritus; Ursodeoxycholic Acid; Vitamins

1997
Effect of cholestasis on regulation of cAMP synthesis by glucagon and bile acids in isolated hepatocytes.
    The American journal of physiology, 1997, Volume: 273, Issue:1 Pt 1

    Topics: Angiotensin II; Animals; Bile; Bile Acids and Salts; Cells, Cultured; Cholestasis; Colforsin; Common Bile Duct; Cricetinae; Cyclic AMP; Glucagon; Isoenzymes; Kinetics; Liver; Male; Mesocricetus; Protein Kinase C; Protein Kinase C-alpha; Receptors, Glucagon; Reference Values; Taurocholic Acid; Ursodeoxycholic Acid

1997
Ursodeoxycholic acid improves cholestasis in infants with cystic fibrosis.
    The Annals of pharmacotherapy, 1997, Volume: 31, Issue:9

    Topics: Cholagogues and Choleretics; Cholestasis; Cystic Fibrosis; Female; Humans; Infant, Newborn; Liver Function Tests; Male; Treatment Outcome; Ursodeoxycholic Acid

1997
Improvement of estradiol-17 beta-D-glucuronide-induced cholestasis by sodium tauroursodeoxycholate therapy in rats.
    Scandinavian journal of gastroenterology, 1997, Volume: 32, Issue:9

    Topics: Animals; Bile; Bile Acids and Salts; Cholestasis; Estradiol; Female; Rats; Rats, Sprague-Dawley; Taurochenodeoxycholic Acid; Ursodeoxycholic Acid

1997
Adjuvant treatment with ursodeoxycholic acid may reduce the incidence of acute cardiac allograft rejection.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 1998, Volume: 17, Issue:6

    Topics: Acute Disease; Cholestasis; Cyclosporine; Female; Graft Rejection; Heart Transplantation; Humans; Immunosuppressive Agents; Male; Middle Aged; Retrospective Studies; Ursodeoxycholic Acid

1998
Changes in G protein expression account for impaired modulation of hepatic cAMP formation after BDL.
    The American journal of physiology, 1998, Volume: 274, Issue:6

    Topics: Angiotensin II; Animals; Cholestasis; Colforsin; Common Bile Duct; Cricetinae; Cyclic AMP; Glucagon; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gs; GTP-Binding Proteins; Keratins; Ligation; Liver; Male; Mesocricetus; Receptors, Glucagon; Taurochenodeoxycholic Acid; Ursodeoxycholic Acid

1998
Induction of the mitochondrial permeability transition as a mechanism of liver injury during cholestasis: a potential role for mitochondrial proteases.
    Biochimica et biophysica acta, 1998, Aug-10, Volume: 1366, Issue:1-2

    Topics: Animals; ATP-Dependent Proteases; Calcium Channels; Calpain; Cholestasis; Enzyme Activation; Glycochenodeoxycholic Acid; Liver; Mitochondria, Liver; Necrosis; Permeability; Serine Endopeptidases; Ursodeoxycholic Acid

1998
Drug-associated acute-onset vanishing bile duct and Stevens-Johnson syndromes in a child.
    Gastroenterology, 1998, Volume: 115, Issue:3

    Topics: Acute Disease; Adult; Bile Duct Diseases; Biopsy; Child; Cholestasis; Female; Humans; Ibuprofen; Liver; Liver Cirrhosis; Prednisone; Stevens-Johnson Syndrome; Tacrolimus; Time Factors; Ursodeoxycholic Acid

1998
[Cholestatic acute hepatitis induced by amoxycillin-clavulanic acid combination. Role of ursodeoxycholic acid in drug-induced cholestasis].
    Revista espanola de enfermedades digestivas, 1998, Volume: 90, Issue:7

    Topics: Aged; Amoxicillin; Anti-Bacterial Agents; Chemical and Drug Induced Liver Injury; Cholagogues and Choleretics; Cholestasis; Clavulanic Acid; Humans; Male; Penicillins; Ursodeoxycholic Acid

1998
Cholestasis of pregnancy: ursodeoxycholic acid therapy.
    Journal of hepatology, 1998, Volume: 29, Issue:5

    Topics: Cholagogues and Choleretics; Cholestasis; Female; Humans; Pregnancy; Pregnancy Complications; Ursodeoxycholic Acid

1998
[Cholestasis: drug therapy].
    Praxis, 1998, Nov-11, Volume: 87, Issue:46

    Topics: Cholagogues and Choleretics; Cholestasis; Diagnosis, Differential; Female; Humans; Liver Cirrhosis, Biliary; Liver Transplantation; Male; Ursodeoxycholic Acid

1998
[Inhibition of the antioxidant protection, microsomal oxidation, and xenobiotic glucuroconjugation in rats with cholestasis and their regulation].
    Biulleten' eksperimental'noi biologii i meditsiny, 1999, Volume: 127, Issue:2

    Topics: Animals; Antioxidants; Cholestasis; Glucuronates; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; Nikethamide; Oxidation-Reduction; Phosphatidylcholines; Rats; S-Adenosylmethionine; Ursodeoxycholic Acid; Xenobiotics

1999
Influence of cholestasis on absorption of ursodeoxycholic acid.
    Digestive diseases and sciences, 1999, Volume: 44, Issue:4

    Topics: Administration, Oral; Aged; Bile Acids and Salts; Bilirubin; Cholagogues and Choleretics; Cholestasis; Drainage; Female; Humans; Intestinal Absorption; Male; Middle Aged; Pancreatic Neoplasms; Ursodeoxycholic Acid

1999
Ursodeoxycholic acid prevents hepatic cytochrome P450 isozyme reduction in rats with deoxycholic acid-induced liver injury.
    Journal of hepatology, 1999, Volume: 31, Issue:2

    Topics: Animals; Cholagogues and Choleretics; Cholestasis; Cytochrome P-450 Enzyme System; Deoxycholic Acid; Liver; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Ursodeoxycholic Acid

1999
[Management of cholestasis in pregnancy].
    Presse medicale (Paris, France : 1983), 1999, Dec-04, Volume: 28, Issue:38

    Topics: Cholestasis; Female; Humans; Pregnancy; Pregnancy Complications; Pruritus; Ursodeoxycholic Acid

1999
[Disturbed functioning of enzyme systems of the microsomal oxidation, glucuro- and glutathione conjugation of xenobiotics in the liver of rats intoxicated by deoxycholate and their correction].
    Biulleten' eksperimental'noi biologii i meditsiny, 2000, Volume: 129, Issue:1

    Topics: Animals; Cholagogues and Choleretics; Cholestasis; Deoxycholic Acid; Glucuronates; Glutathione; Male; Microsomes, Liver; Nikethamide; Rats; S-Adenosylmethionine; Ursodeoxycholic Acid; Vitamin E; Xenobiotics

2000
Metabolism and effects on cholestasis of isoursodeoxycholic and ursodeoxycholic acids in bile duct ligated rats.
    Biochimica et biophysica acta, 2001, Apr-03, Volume: 1526, Issue:1

    Topics: Animals; Bile; Bile Acids and Salts; Bile Ducts; Body Weight; Cholestasis; Cholic Acids; Eating; Ligation; Liver; Liver Function Tests; Male; Rats; Rats, Sprague-Dawley; Ursodeoxycholic Acid

2001
Arthrogryposis, renal dysfunction and cholestasis syndrome.
    Saudi medical journal, 2000, Volume: 21, Issue:3

    Topics: Abnormalities, Multiple; Acidosis, Renal Tubular; Arthrogryposis; Atrophy; Cholestasis; Consanguinity; Corpus Callosum; Female; Genes, Recessive; Hearing Loss, Sensorineural; Heart Defects, Congenital; Humans; Infant, Newborn; Pedigree; Retrospective Studies; Saudi Arabia; Syndrome; Ursodeoxycholic Acid

2000
Flipping over flippases.
    Journal of pediatric gastroenterology and nutrition, 2001, Volume: 33, Issue:1

    Topics: Adolescent; Adult; Animals; Child; Child, Preschool; Cholagogues and Choleretics; Cholestasis; Female; Gene Deletion; Genes, MDR; Humans; Infant; Infant, Newborn; Male; Mice; Mice, Knockout; Middle Aged; Mutation, Missense; Ursodeoxycholic Acid

2001
Mucolipidosis II (I-cell disease) presenting as neonatal cholestasis.
    Journal of inherited metabolic disease, 2001, Volume: 24, Issue:5

    Topics: Bile Ducts; Cholestasis; Female; Humans; Infant, Newborn; Liver; Liver Function Tests; Mucolipidoses; Ultrasonography; Ursodeoxycholic Acid

2001
Acute cholestatic hepatitis after exposure to isoflurane.
    The Annals of pharmacotherapy, 2002, Volume: 36, Issue:2

    Topics: Acetylcysteine; Acute Disease; Aged; Anesthetics, Inhalation; Biopsy; Chemical and Drug Induced Liver Injury; Cholestasis; Female; Humans; Isoflurane; Liver; Liver Function Tests; Ursodeoxycholic Acid

2002
The UDCA dosage deficit: a fate shared with CDCA.
    European journal of gastroenterology & hepatology, 2002, Volume: 14, Issue:3

    Topics: Chenodeoxycholic Acid; Cholelithiasis; Cholestasis; Dose-Response Relationship, Drug; Humans; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

2002
Ursodeoxycholate and tauroursodeoxycholate inhibit cholangiocyte growth and secretion of BDL rats through activation of PKC alpha.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:5

    Topics: Animals; Apoptosis; Bile Acids and Salts; Bile Ducts; Calcium; Carrier Proteins; Cell Division; Cholagogues and Choleretics; Cholestasis; Down-Regulation; Hepatitis; Hydroxysteroid Dehydrogenases; Isoenzymes; Ligation; Liver; Male; Membrane Glycoproteins; Organ Size; Protein Kinase C; Protein Kinase C-alpha; Rats; Rats, Inbred F344; Taurochenodeoxycholic Acid; Ursodeoxycholic Acid

2002
[Ursodeoxycholic acid promotes liver regeneration after partial hepatectomy in bile duct obstructive rats].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2002, Volume: 10, Issue:2

    Topics: Animals; Cholestasis; Gene Expression Regulation; Hepatectomy; Hepatocyte Growth Factor; Liver; Liver Regeneration; Male; Proto-Oncogene Proteins c-met; Rats; Rats, Wistar; RNA, Messenger; Ursodeoxycholic Acid

2002
Treatment of severe cholestasis in neonatal Dubin-Johnson syndrome with ursodeoxycholic acid.
    Journal of perinatal medicine, 2002, Volume: 30, Issue:2

    Topics: Bilirubin; Cholestasis; Humans; Hyperbilirubinemia; Infant, Newborn; Jaundice, Chronic Idiopathic; Male; Ursodeoxycholic Acid

2002
[Ursotherapy in hepatobiliary diseases].
    Acta gastroenterologica Latinoamericana, 1992, Volume: 22, Issue:3

    Topics: Chenodeoxycholic Acid; Cholelithiasis; Cholestasis; Humans; Liver Diseases; Ursodeoxycholic Acid

1992
Effects of ursodeoxycholic acid on liver function in patients with cystic fibrosis and chronic cholestasis.
    The Journal of pediatrics, 1992, Volume: 121, Issue:1

    Topics: 5'-Nucleotidase; Adolescent; Adult; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Bile Acids and Salts; Bilirubin; Child; Cholestasis; Chronic Disease; Cystic Fibrosis; Female; gamma-Glutamyltransferase; Humans; Liver; Male; Ursodeoxycholic Acid

1992
Microtubule-independent choleresis and anti-cholestatic action of tauroursodeoxycholate in colchicine-treated rat liver.
    The Biochemical journal, 1992, Dec-01, Volume: 288 ( Pt 2)

    Topics: Animals; Aspartate Aminotransferases; Bile; Cholestasis; Colchicine; gamma-Glutamyltransferase; Male; Microtubules; Rats; Rats, Inbred Strains; Secretory Rate; Taurochenodeoxycholic Acid; Taurocholic Acid; Ursodeoxycholic Acid

1992
[Drug therapy of cholestatic hepatopathies].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1992, Aug-18, Volume: 81, Issue:34

    Topics: Cholangitis, Sclerosing; Cholestasis; Humans; Liver Cirrhosis, Biliary; Long-Term Care; Ursodeoxycholic Acid

1992
Ursodeoxycholic acid limits liver histologic alterations and portal hypertension induced by bile duct ligation in the rat.
    Gastroenterology, 1992, Volume: 102, Issue:5

    Topics: Animals; Cholestasis; Hemodynamics; Hypertension, Portal; Liver; Male; Rats; Rats, Inbred Strains; Ursodeoxycholic Acid

1992
Lack of benefit of ursodeoxycholic acid in drug-induced cholestasis in the rat.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1992, Volume: 200, Issue:1

    Topics: 1-Naphthylisothiocyanate; Animals; Cholestasis; Cyclosporine; Ethinyl Estradiol; Male; Rats; Rats, Inbred Strains; Ursodeoxycholic Acid

1992
The effectual level of ursodeoxycholic acid in therapy for non-advanced chronic cholestasis is fifty percent of total serum bile acids.
    Gastroenterologia Japonica, 1992, Volume: 27, Issue:2

    Topics: Adult; Aged; Bile Acids and Salts; Cholangitis, Sclerosing; Cholestasis; Female; Humans; Liver Cirrhosis, Biliary; Liver Function Tests; Male; Middle Aged; Ursodeoxycholic Acid

1992
Bile acid N-acetylglucosaminidation. In vivo and in vitro evidence for a selective conjugation reaction of 7 beta-hydroxylated bile acids in humans.
    The Journal of clinical investigation, 1992, Volume: 89, Issue:6

    Topics: Acetylglucosamine; Administration, Oral; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Deoxycholic Acid; Glycosides; Humans; Hydroxylation; Liver Diseases; Mass Spectrometry; Ursodeoxycholic Acid

1992
Synthesis of 13C-labeled chenodeoxycholic, hyodeoxycholic, and ursodeoxycholic acids for the study of bile acid metabolism in liver disease.
    Clinica chimica acta; international journal of clinical chemistry, 1991, Nov-09, Volume: 203, Issue:1

    Topics: Administration, Oral; Carbon Isotopes; Chenodeoxycholic Acid; Cholestasis; Chromatography, Thin Layer; Deoxycholic Acid; Gas Chromatography-Mass Spectrometry; Humans; Isotope Labeling; Spectrophotometry, Infrared; Ursodeoxycholic Acid

1991
Mechanism of ursodeoxycholic acid- and canrenoate-induced biliary bicarbonate secretion and the effect on glucose- and amino acid-induced cholestasis.
    Scandinavian journal of gastroenterology, 1991, Volume: 26, Issue:5

    Topics: Amino Acids; Animals; Bicarbonates; Bile; Bile Acids and Salts; Canrenoic Acid; Cholagogues and Choleretics; Cholestasis; Glucose; Infusions, Intravenous; Swine; Ursodeoxycholic Acid

1991
Ursodeoxycholic acid for the treatment of home parenteral nutrition-associated cholestasis. A case report.
    Gastroenterology, 1991, Volume: 101, Issue:1

    Topics: Adult; Cholestasis; Humans; Male; Parenteral Nutrition, Home; Time Factors; Ursodeoxycholic Acid

1991
Formation of iso-ursodeoxycholic acid during administration of ursodeoxycholic acid in man.
    Journal of hepatology, 1991, Volume: 13, Issue:1

    Topics: Adult; Aminopyrine; Bile; Bile Acids and Salts; Carbon Isotopes; Carbon Radioisotopes; Cholestasis; Female; Humans; Intestines; Liver Diseases; Male; Microsomes, Liver; Middle Aged; Ursodeoxycholic Acid

1991
[Use of ursodeoxycholic acid in the treatment of hepato-biliary complications in cystic fibrosis].
    Pathologie-biologie, 1991, Volume: 39, Issue:6

    Topics: Adolescent; Adult; Child; Cholestasis; Cystic Fibrosis; Female; Humans; Liver; Male; Ursodeoxycholic Acid

1991
Conjugates of ursodeoxycholate protect against cholestasis and hepatocellular necrosis caused by more hydrophobic bile salts. In vivo studies in the rat.
    Gastroenterology, 1991, Volume: 100, Issue:1

    Topics: Animals; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Cholestasis; Liver Diseases; Male; Necrosis; Rats; Rats, Inbred Strains; Ursodeoxycholic Acid

1991
Cystic fibrosis: another use for urso?
    Gastroenterology, 1991, Volume: 100, Issue:3

    Topics: Adolescent; Adult; Child; Cholestasis; Cystic Fibrosis; Humans; Liver; Nutritional Status; Ursodeoxycholic Acid

1991
Liver dysfunction in cystic fibrosis--beneficial effect of bile acid treatment.
    Gastroenterology, 1991, Volume: 100, Issue:5 Pt 1

    Topics: Bile Acids and Salts; Child; Cholestasis; Cystic Fibrosis; Humans; Liver Function Tests; Taurine; Ursodeoxycholic Acid

1991
Effective treatment of cyclosporine-induced cholestasis in heart-transplanted patients treated with ursodeoxycholic acid.
    Transplantation, 1991, Volume: 51, Issue:5

    Topics: Alkaline Phosphatase; Cholestasis; Cyclosporins; Heart Transplantation; Humans; Ursodeoxycholic Acid

1991
Lipoprotein (a) serum levels in chronic cholestatic liver disease during treatment with ursodeoxycholic acid.
    Archives of internal medicine, 1991, Volume: 151, Issue:6

    Topics: Cholestasis; Chronic Disease; Humans; Lipoproteins; Ursodeoxycholic Acid

1991
Formation of biliary thrombi in protoporphyrin-induced cholestasis in perfused rat liver.
    Hepatology (Baltimore, Md.), 1990, Volume: 11, Issue:5

    Topics: Animals; Bile; Bile Acids and Salts; Biliary Tract Diseases; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholestasis; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Liver Diseases; Microscopy, Electron; Perfusion; Porphyrins; Protoporphyrins; Rats; Rats, Inbred Strains; Taurocholic Acid; Ursodeoxycholic Acid

1990
Cholesterol and bile acid metabolism in cultures of primary rat bile ductular epithelial cells.
    Hepatology (Baltimore, Md.), 1990, Volume: 11, Issue:6

    Topics: Animals; Bile Acids and Salts; Bile Ducts; Cell Separation; Cells, Cultured; Cholestasis; Cholesterol; Cholic Acid; Cholic Acids; Deoxycholic Acid; Epithelial Cells; Epithelium; Lithocholic Acid; Male; Rats; Rats, Inbred Strains; Ursodeoxycholic Acid

1990
Effects of ursodeoxycholic acid treatment on nutrition and liver function in patients with cystic fibrosis and longstanding cholestasis.
    Gut, 1990, Volume: 31, Issue:8

    Topics: Adolescent; Adult; Child; Cholestasis; Chronic Disease; Cystic Fibrosis; Deoxycholic Acid; Female; Humans; Liver; Liver Function Tests; Male; Nutritional Status; Prospective Studies; Ursodeoxycholic Acid

1990
Treatment of primary biliary cirrhosis and cholestatic disorders with ursodeoxycholic acid.
    Lancet (London, England), 1987, Aug-29, Volume: 2, Issue:8557

    Topics: Cholestasis; Deoxycholic Acid; Double-Blind Method; Follow-Up Studies; Humans; Liver Cirrhosis, Biliary; Prospective Studies; Ursodeoxycholic Acid

1987
Prevention of endotoxaemia in obstructive jaundice--a comparative study of bile salts.
    HPB surgery : a world journal of hepatic, pancreatic and biliary surgery, 1988, Volume: 1, Issue:1

    Topics: Animals; Bile Acids and Salts; Chenodeoxycholic Acid; Cholestasis; Cholic Acid; Cholic Acids; Deoxycholic Acid; Endotoxins; Escherichia coli; Glycodeoxycholic Acid; Intestinal Absorption; Male; Rats; Rats, Inbred Strains; Taurocholic Acid; Taurodeoxycholic Acid; Ursodeoxycholic Acid

1988
Effect of ursodeoxycholate on the biliary excretion of cefotiam and sulbenicillin in patients with percutaneous transhepatic biliary drainage.
    Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:5

    Topics: Aged; Bile; Bile Acids and Salts; Cefotaxime; Cefotiam; Cholestasis; Deoxycholic Acid; Drainage; Female; Humans; Male; Middle Aged; Penicillin G; Sulbenicillin; Ursodeoxycholic Acid

1988
Endotoxemia in obstructive jaundice. Observations on cause and clinical significance.
    American journal of surgery, 1988, Volume: 155, Issue:2

    Topics: Cholestasis; Endotoxins; Female; Humans; Kidney; Male; Middle Aged; Postoperative Complications; Preoperative Care; Risk Factors; Ursodeoxycholic Acid

1988
[Bile acids in chronic hepatopathies].
    Minerva medica, 1986, Dec-22, Volume: 77, Issue:49-50

    Topics: Adult; Bile Acids and Salts; Cholestasis; Chronic Disease; Diagnosis, Differential; Hepatitis, Chronic; Humans; Liver Cirrhosis; Liver Diseases; Middle Aged; Ursodeoxycholic Acid

1986
[Effect of ursodeoxycholic acid on biliary excretion of cefotiam in patients with percutaneous transhepatic biliary drainage].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1985, Volume: 82, Issue:3

    Topics: Aged; Bile; Cefotaxime; Cefotiam; Cholestasis; Deoxycholic Acid; Drainage; Female; Humans; Male; Middle Aged; Ursodeoxycholic Acid

1985