Page last updated: 2024-08-23

ursodeoxycholic acid and Bile Duct Cancer

ursodeoxycholic acid has been researched along with Bile Duct Cancer in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (19.35)18.2507
2000's12 (38.71)29.6817
2010's10 (32.26)24.3611
2020's3 (9.68)2.80

Authors

AuthorsStudies
Karlsen, TH; Vesterhus, M1
Ferenci, P; Halilbasic, E; Stättermayer, AF; Trauner, M; Wrba, F1
Hong, EM; Jang, HJ; Jung, JH; Kim, JH; Koh, DH; Lee, J; Park, SW1
Beuers, U; Herta, T1
Bancel, B; Brunel, T; Goubault, P; Mabrut, JY; Mohkam, K; Rode, A1
Eaton, JE; Gores, GJ; Lazaridis, KN; Lindor, KD; Talwalkar, JA1
Chung, CW; Jeong, YI; Kang, DH; Kim, CH; Kim, DH; Kwak, TW; Lee, HM1
Boberg, KM; Karlsen, TH; Vesterhus, M1
Banales, JM; Briz, O; Hernández-Hernández, A; Lozano, E; Macias, RI; Marin, JJ; Monte, MJ1
Geier, A; Tischendorf, JJ; Trautwein, C1
Lindor, KD; Silveira, MG1
Fickert, P; Halilbasic, E; Moustafa, T; Trauner, M1
Cullen, S; Maggs, J1
Chazouillères, O; Chrétien, Y; Corphechot, C; Garioud, A; Poupon, R; Poupon, RE; Seksik, P1
Gotthardt, D; Kloeters-Plachky, P; Kulaksiz, H; Rost, D; Rudolph, G; Stiehl, A1
Boberg, KM; Karlsen, TH; Schrumpf, E1
Ponsioen, CY1
Blendis, L; Lurie, Y1
Stiehl, A1
Petersen-Benz, C; Stiehl, A1
Gatzen, M; Pausch, J1
Charatcharoenwitthaya, P; Lindor, KD1
Kloeters-Plachky, P; Rost, D; Rudolph, G; Stiehl, A1
Fitz, JG; McGill, JM; Schlenker, T; Shimokura, GH1
Finnie, I; Gilmore, I; Lombard, MJ; Rhodes, JM; Sutton, R1
Ghosh, S; Palmer, KR1
Crepaldi, G; Knuth, A; Poci, C; Sartori, L; Spirlí, C; Strazzabosco, M1
Benz, C; Sauer, P; Stiehl, A1
Franco, J; Saeian, K1
Fleig, WE; Halm, U; Keim, V; Mössner, J1
Grüne, S; Moradpour, D; Müllhaupt, B; Münch, R; Siegenthaler, W; Siegenthaler-Zuber, G1

Reviews

16 review(s) available for ursodeoxycholic acid and Bile Duct Cancer

ArticleYear
Emerging therapies in primary sclerosing cholangitis: pathophysiological basis and clinical opportunities.
    Journal of gastroenterology, 2020, Volume: 55, Issue:6

    Topics: Bile Duct Neoplasms; Cholagogues and Choleretics; Cholangiocarcinoma; Cholangitis, Sclerosing; Clinical Trials as Topic; Colorectal Neoplasms; Humans; Liver Transplantation; Research Design; Severity of Illness Index; Ursodeoxycholic Acid

2020
Variants in ABCB4 (MDR3) across the spectrum of cholestatic liver diseases in adults.
    Journal of hepatology, 2020, Volume: 73, Issue:3

    Topics: Adult; ATP Binding Cassette Transporter, Subfamily B; Bile Duct Neoplasms; Chemical and Drug Induced Liver Injury; Cholelithiasis; Cholestasis, Intrahepatic; Female; Gallbladder Neoplasms; Humans; Liver Cirrhosis; Liver Transplantation; Male; Polymorphism, Single Nucleotide; Pregnancy; Pregnancy Complications; Treatment Outcome; Ursodeoxycholic Acid; Young Adult

2020
[Immune-mediated cholangiopathies : Diagnostic and therapeutic challenges].
    Der Radiologe, 2019, Volume: 59, Issue:4

    Topics: Bile Duct Diseases; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Humans; Liver Cirrhosis, Biliary; Ursodeoxycholic Acid

2019
Low-Phospholipid Associated Cholelithiasis (LPAC) syndrome: A synthetic review.
    Journal of visceral surgery, 2019, Volume: 156, Issue:4

    Topics: Adult; Age Factors; ATP Binding Cassette Transporter, Subfamily B; Bile; Bile Duct Neoplasms; Cholagogues and Choleretics; Cholangiocarcinoma; Cholangitis; Cholangitis, Sclerosing; Cholecystectomy; Cholelithiasis; Codon, Nonsense; Diagnosis, Differential; Female; Gallstones; Humans; Lithiasis; Liver Abscess; Liver Cirrhosis, Biliary; Liver Diseases; Mutation; Phosphatidylcholines; Pregnancy; Pregnancy Complications; Recurrence; Syndrome; Ultrasonography; Ursodeoxycholic Acid

2019
Pathogenesis of primary sclerosing cholangitis and advances in diagnosis and management.
    Gastroenterology, 2013, Volume: 145, Issue:3

    Topics: Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cholagogues and Choleretics; Cholangiocarcinoma; Cholangiopancreatography, Endoscopic Retrograde; Cholangitis, Sclerosing; Colonic Neoplasms; Combined Modality Therapy; Diagnosis, Differential; Gallbladder Neoplasms; Genetic Predisposition to Disease; Humans; Immunity, Innate; Immunosuppressive Agents; Intestines; Liver Transplantation; Metagenome; Ursodeoxycholic Acid

2013
Review article: controversies in the management of primary biliary cirrhosis and primary sclerosing cholangitis.
    Alimentary pharmacology & therapeutics, 2014, Volume: 39, Issue:3

    Topics: Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cholangiocarcinoma; Cholangitis, Sclerosing; Humans; Immunosuppression Therapy; Liver Cirrhosis, Biliary; Liver Transplantation; Prognosis; Time Factors; Ursodeoxycholic Acid

2014
Current diagnosis and management of primary sclerosing cholangitis.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2008, Volume: 14, Issue:6

    Topics: Algorithms; Bile Duct Diseases; Bile Duct Neoplasms; Cholangiocarcinoma; Cholangitis, Sclerosing; Constriction, Pathologic; Endoscopy; Gastroenterology; Humans; Liver Transplantation; Prognosis; Treatment Outcome; Ultrasonography; Ursodeoxycholic Acid

2008
Primary sclerosing cholangitis.
    Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2008, Volume: 22, Issue:8

    Topics: Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cholagogues and Choleretics; Cholangiocarcinoma; Cholangiography; Cholangitis, Sclerosing; Humans; Liver; Liver Transplantation; Prognosis; Recurrence; Ursodeoxycholic Acid

2008
Lessons from the toxic bile concept for the pathogenesis and treatment of cholestatic liver diseases.
    Wiener medizinische Wochenschrift (1946), 2008, Volume: 158, Issue:19-20

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Bile; Bile Acids and Salts; Bile Canaliculi; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Cholangiocarcinoma; Cholangitis, Sclerosing; Cholestasis, Intrahepatic; Cholic Acids; Disease Models, Animal; Humans; Liver Neoplasms; Mice; Mice, Knockout; Mutation; Norsteroids; Ursodeoxycholic Acid

2008
Management of autoimmune liver disease.
    Minerva gastroenterologica e dietologica, 2009, Volume: 55, Issue:2

    Topics: Autoantibodies; Azathioprine; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Carcinoma, Hepatocellular; Cholagogues and Choleretics; Cholangiocarcinoma; Clinical Trials as Topic; Drug Therapy, Combination; Evidence-Based Medicine; Glucocorticoids; Hepatitis, Autoimmune; Humans; Immunosuppressive Agents; Liver Neoplasms; Liver Transplantation; Prognosis; Randomized Controlled Trials as Topic; Risk Factors; Ursodeoxycholic Acid

2009
Primary sclerosing cholangitis.
    Best practice & research. Clinical gastroenterology, 2010, Volume: 24, Issue:5

    Topics: Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cholangiocarcinoma; Cholangiography; Cholangitis, Sclerosing; Comorbidity; Disease Progression; Gallbladder Neoplasms; Genetic Predisposition to Disease; Genome-Wide Association Study; Humans; Inflammatory Bowel Diseases; Linkage Disequilibrium; Liver Cirrhosis; Liver Transplantation; Practice Guidelines as Topic; Prognosis; Risk Factors; Ursodeoxycholic Acid

2010
Recent insights in primary sclerosing cholangitis.
    Journal of digestive diseases, 2012, Volume: 13, Issue:7

    Topics: Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cholagogues and Choleretics; Cholangiocarcinoma; Cholangitis, Sclerosing; Colorectal Neoplasms; Humans; Inflammatory Bowel Diseases; Liver Transplantation; Ursodeoxycholic Acid

2012
[Primary sclerosing cholangitis].
    Der Internist, 2004, Volume: 45, Issue:1

    Topics: Bile Duct Neoplasms; Cholangitis, Sclerosing; Colitis, Ulcerative; Colorectal Neoplasms; Comorbidity; Humans; Liver Function Tests; Prognosis; Risk Factors; Ursodeoxycholic Acid

2004
[Treatment of cholestatic hepatic diseases: more than the substitution of fat soluble vitamins?].
    Der Internist, 2006, Volume: 47, Issue:12

    Topics: Adult; Age Factors; Bile Acids and Salts; Bile Duct Neoplasms; Cholangiocarcinoma; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Infant; Infant, Newborn; Liver Cirrhosis, Biliary; Long-Term Care; Middle Aged; Pregnancy; Risk Factors; Ursodeoxycholic Acid

2006
Primary sclerosing cholangitis.
    Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2000, Volume: 14, Issue:4

    Topics: Bile Duct Neoplasms; Bile Ducts; Cholagogues and Choleretics; Cholangitis, Sclerosing; Colonic Neoplasms; Constriction, Pathologic; Humans; Liver Transplantation; Ursodeoxycholic Acid

2000
Biliary tract inflammatory disorders: primary sclerosing cholangitis and primary biliary cirrhosis.
    Current gastroenterology reports, 1999, Volume: 1, Issue:2

    Topics: Bile Duct Neoplasms; Cholangiocarcinoma; Cholangitis, Sclerosing; Humans; Liver Cirrhosis, Biliary; Liver Transplantation; Risk Factors; Ursodeoxycholic Acid

1999

Trials

4 trial(s) available for ursodeoxycholic acid and Bile Duct Cancer

ArticleYear
Impact of dominant stenoses on the serum level of the tumor marker CA19-9 in patients with primary sclerosing cholangitis.
    Zeitschrift fur Gastroenterologie, 2005, Volume: 43, Issue:6

    Topics: Bile Duct Neoplasms; Biomarkers, Tumor; CA-19-9 Antigen; Cholagogues and Choleretics; Cholangitis, Sclerosing; Cohort Studies; Constriction, Pathologic; Dilatation; Humans; Longitudinal Studies; Risk Assessment; Risk Factors; Treatment Outcome; Ursodeoxycholic Acid

2005
Preventing biliary stent occlusion.
    Lancet (London, England), 1994, Oct-15, Volume: 344, Issue:8929

    Topics: Bile Duct Neoplasms; Cholestasis; Humans; Stents; Ursodeoxycholic Acid

1994
Prevention of biliary stent occlusion using cyclical antibiotics and ursodeoxycholic acid.
    Gut, 1994, Volume: 35, Issue:12

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Bile Duct Neoplasms; Cholangiocarcinoma; Cholestasis, Extrahepatic; Female; Humans; Male; Middle Aged; Pancreatic Neoplasms; Postoperative Complications; Stents; Treatment Outcome; Ursodeoxycholic Acid

1994
Ofloxacin and ursodeoxycholic acid versus ursodeoxycholic acid alone to prevent occlusion of biliary stents: a prospective, randomized trial.
    Endoscopy, 2001, Volume: 33, Issue:6

    Topics: Aged; Anti-Infective Agents; Bile Duct Neoplasms; Cholagogues and Choleretics; Cholestasis, Extrahepatic; Drug Therapy, Combination; Female; Humans; Male; Ofloxacin; Postoperative Complications; Prospective Studies; Stents; Ursodeoxycholic Acid

2001

Other Studies

11 other study(ies) available for ursodeoxycholic acid and Bile Duct Cancer

ArticleYear
Ursodeoxycholic acid shows antineoplastic effects in bile duct cancer cells via apoptosis induction; p53 activation; and EGFR-ERK, COX-2, and PI3K-AKT pathway inhibition.
    Molecular biology reports, 2021, Volume: 48, Issue:9

    Topics: Antineoplastic Agents; Apoptosis; Bile Duct Neoplasms; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2; Deoxycholic Acid; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Signal Transduction; Tumor Suppressor Protein p53; Ursodeoxycholic Acid

2021
Ursodeoxycholic acid-conjugated chitosan for photodynamic treatment of HuCC-T1 human cholangiocarcinoma cells.
    International journal of pharmaceutics, 2013, Sep-15, Volume: 454, Issue:1

    Topics: Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biological Transport; Cell Line, Tumor; Chemistry, Pharmaceutical; Chitosan; Chlorophyllides; Cholangiocarcinoma; Drug Carriers; Humans; Magnetic Resonance Spectroscopy; Microscopy, Electron, Transmission; Particle Size; Photochemotherapy; Photosensitizing Agents; Porphyrins; Reactive Oxygen Species; Technology, Pharmaceutical; Ursodeoxycholic Acid

2013
Enhanced antitumour drug delivery to cholangiocarcinoma through the apical sodium-dependent bile acid transporter (ASBT).
    Journal of controlled release : official journal of the Controlled Release Society, 2015, Oct-28, Volume: 216

    Topics: Aged; Aged, 80 and over; Animals; Antineoplastic Agents; Bile Duct Neoplasms; Cell Line, Tumor; Cell Proliferation; Cholangiocarcinoma; Cisplatin; Drug Delivery Systems; Female; Humans; Male; Mice; Mice, Nude; Middle Aged; Organic Anion Transporters, Sodium-Dependent; Organoplatinum Compounds; Rats; Rats, Wistar; Symporters; Ursodeoxycholic Acid

2015
Characteristics and clinical course of primary sclerosing cholangitis in France: a prospective cohort study.
    European journal of gastroenterology & hepatology, 2010, Volume: 22, Issue:7

    Topics: Adolescent; Adult; Aged; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Carcinoma, Hepatocellular; Cholangiocarcinoma; Cholangitis, Sclerosing; Cohort Studies; Colorectal Neoplasms; Female; France; Gallbladder Neoplasms; Humans; Incidence; Liver Failure; Liver Neoplasms; Liver Transplantation; Male; Middle Aged; Prognosis; Prospective Studies; Treatment Outcome; Ursodeoxycholic Acid; Young Adult

2010
In PSC with dominant bile duct stenosis, IBD is associated with an increase of carcinomas and reduced survival.
    Journal of hepatology, 2010, Volume: 53, Issue:2

    Topics: Adolescent; Adult; Aged; Bile Duct Neoplasms; Cholangitis, Sclerosing; Cholestasis; Colorectal Neoplasms; Comorbidity; Female; Follow-Up Studies; Gallbladder Neoplasms; Humans; Incidence; Inflammatory Bowel Diseases; Kaplan-Meier Estimate; Liver Transplantation; Longitudinal Studies; Male; Middle Aged; Prospective Studies; Survival Rate; Ursodeoxycholic Acid; Young Adult

2010
Primary sclerosing cholangitis: a premalignant condition.
    Gastroenterology, 2002, Volume: 123, Issue:2

    Topics: Bile Duct Neoplasms; Cholangitis, Sclerosing; Humans; Liver Neoplasms; Pancreatic Neoplasms; Precancerous Conditions; Ursodeoxycholic Acid

2002
Primary sclerosing cholangitis: patients with a rising alkaline phosphatase at annual follow-up.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2007, Volume: 5, Issue:1

    Topics: Alkaline Phosphatase; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biomarkers, Tumor; Biopsy; CA-19-9 Antigen; Carcinoembryonic Antigen; Cholagogues and Choleretics; Cholangiocarcinoma; Cholangitis, Sclerosing; Colitis, Ulcerative; Diagnostic Imaging; Disease Progression; Humans; Male; Middle Aged; Practice Guidelines as Topic; Ursodeoxycholic Acid

2007
The incidence of cholangiocarcinoma in primary sclerosing cholangitis after long-time treatment with ursodeoxycholic acid.
    European journal of gastroenterology & hepatology, 2007, Volume: 19, Issue:6

    Topics: Adolescent; Adult; Aged; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Child; Cholagogues and Choleretics; Cholangiocarcinoma; Cholangitis, Sclerosing; Cholestasis, Intrahepatic; Female; Humans; Long-Term Care; Male; Middle Aged; Patient Dropouts; Prospective Studies; Ursodeoxycholic Acid

2007
Ursodeoxycholate increases cytosolic calcium concentration and activates Cl- currents in a biliary cell line.
    Gastroenterology, 1995, Volume: 109, Issue:3

    Topics: Bile Duct Neoplasms; Calcium; Cell Membrane Permeability; Chloride Channels; Cholangiocarcinoma; Cytosol; Humans; Membrane Potentials; Patch-Clamp Techniques; Tumor Cells, Cultured; Ursodeoxycholic Acid

1995
Effect of ursodeoxycholic acid on intracellular pH in a bile duct epithelium-like cell line.
    Hepatology (Baltimore, Md.), 1994, Volume: 19, Issue:1

    Topics: Acid-Base Equilibrium; Bicarbonates; Bile Duct Neoplasms; Bile Ducts; Bile Ducts, Intrahepatic; Biological Transport; Cholangiocarcinoma; Diffusion; Epithelium; Humans; Hydrogen-Ion Concentration; Tumor Cells, Cultured; Ursodeoxycholic Acid

1994
[Primary sclerosing cholangitis].
    Deutsche medizinische Wochenschrift (1946), 1991, Jul-12, Volume: 116, Issue:28-29

    Topics: Adenoma, Bile Duct; Adult; Bile Duct Neoplasms; Cholangiopancreatography, Endoscopic Retrograde; Cholangitis, Sclerosing; Diagnosis, Differential; Hepatic Duct, Common; Humans; Liver Transplantation; Male; Prognosis; Ursodeoxycholic Acid

1991