Compounds > ursodeoxycholic acid
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ursodeoxycholic acid and Barrett Esophagus

ursodeoxycholic acid has been researched along with Barrett Esophagus in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (18.18)29.6817
2010's8 (72.73)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Dunbar, KB; Huo, X; Souza, RF; Spechler, SJ; Zhang, Q; Zhang, X1
Asanuma, K; Chen, M; Cheng, E; Huo, X; Peng, S; Pham, TH; Rezaei, D; Souza, RF; Spechler, SJ; Wang, DH; Yu, C; Zhang, Q; Zhang, X1
Banerjee, B; Chow, HH; Della'Zanna, G; Gibson, BA; Hsu, CH; Martinez, JA; Richmond, E; Shaheen, NJ; Trowers, E1
Reid, BJ1
Adler, E; Bernstein, C; Bernstein, H; Condon, A; Dvorak, K; Goldman, A; Minnella, M1
Burnat, G; Konturek, PC; Majka, J1
Almada, LL; Buttar, NS; Comba, A; Demars, CJ; Fernández-Zapico, ME; Gainullin, VG; Lomberk, G; Rizvi, S; Rizvi, Z; Wang, K1
Onuchina, EV; Osipenko, MF; Tsukanov, VV1
Cheng, E; Huo, X; Juergens, S; Meyer, F; Rezaei, D; Souza, RF; Spechler, SJ; Strauch, ED; Wang, DH; Wang, JY; Yu, C; Zhang, Q; Zhang, X1
Ajani, J; Buttar, NS; Chen, CT; Chou, CK; Guha, S; Hsu, JM; Huang, P; Hung, MC; Izzo, JG; Kuo, HP; Lee, DF; Sun, HL; Wang, KK; Wei, Y; Wu, TT; Yen, CJ1
Bergman, JJ; Bozikas, A; Krishnadath, KK; Kulik, W; Marsman, WA; Rosmolen, WD; ten Kate, FJ; van Baal, JW1

Trials

3 trial(s) available for ursodeoxycholic acid and Barrett Esophagus

ArticleYear
In Barrett's esophagus patients and Barrett's cell lines, ursodeoxycholic acid increases antioxidant expression and prevents DNA damage by bile acids.
    American journal of physiology. Gastrointestinal and liver physiology, 2014, Jul-15, Volume: 307, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anticarcinogenic Agents; Antioxidants; Barrett Esophagus; Catalase; Cell Line; Deoxycholic Acid; DNA Damage; Epithelial Cells; Esophageal Neoplasms; Esophagus; Female; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Histones; Humans; Male; Middle Aged; NF-E2-Related Factor 2; Phosphorylation; RNA Interference; RNA, Messenger; Time Factors; Transcription Factor RelA; Transfection; Treatment Outcome; Up-Regulation; Ursodeoxycholic Acid

2014
Clinical Study of Ursodeoxycholic Acid in Barrett's Esophagus Patients.
    Cancer prevention research (Philadelphia, Pa.), 2016, Volume: 9, Issue:7

    Topics: Adult; Aged; Apoptosis; Barrett Esophagus; Bile Acids and Salts; Cell Proliferation; Cholagogues and Choleretics; DNA Damage; Female; Humans; Male; Middle Aged; Oxidative Stress; Pilot Projects; Ursodeoxycholic Acid

2016
[Drug UDCA (Ursosan) in therapeutic management of patients Barrett's esophagus].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2010, Issue:12

    Topics: Age Factors; Aged; Anti-Ulcer Agents; Barrett Esophagus; Cholagogues and Choleretics; Female; Follow-Up Studies; Humans; Male; Omeprazole; Prospective Studies; Ursodeoxycholic Acid

2010

Other Studies

8 other study(ies) available for ursodeoxycholic acid and Barrett Esophagus

ArticleYear
In Barrett's epithelial cells, weakly acidic bile salt solutions cause oxidative DNA damage with response and repair mediated by p38.
    American journal of physiology. Gastrointestinal and liver physiology, 2020, 03-01, Volume: 318, Issue:3

    Topics: Barrett Esophagus; Cell Line, Transformed; Cell Proliferation; Deoxycholic Acid; DNA Damage; DNA Repair; Epithelial Cells; Esophageal Mucosa; Female; Histones; Humans; Hydrogen-Ion Concentration; Male; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Primary Cell Culture; S Phase Cell Cycle Checkpoints; Signal Transduction; Tumor Suppressor Protein p53; Ursodeoxycholic Acid

2020
Surrogate Markers: Lessons from the Next Gen?
    Cancer prevention research (Philadelphia, Pa.), 2016, Volume: 9, Issue:7

    Topics: Barrett Esophagus; Biomarkers; Humans; Mass Screening; Neoplasms; Ursodeoxycholic Acid

2016
Protective effects of glycoursodeoxycholic acid in Barrett's esophagus cells.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2010, Volume: 23, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Antioxidants; Barrett Esophagus; Bile Acids and Salts; Cell Line; Cell Proliferation; Cell Survival; Cytoprotection; Deoxycholic Acid; Deoxyguanosine; DNA Damage; Esophagus; Free Radical Scavengers; Glycochenodeoxycholic Acid; Glycocholic Acid; Glycodeoxycholic Acid; Humans; Hydrogen-Ion Concentration; Oxidative Stress; Protective Agents; Reactive Oxygen Species; RNA; Sulfhydryl Compounds; Superoxide Dismutase; Taurocholic Acid; Time Factors; Ursodeoxycholic Acid

2010
Bile acids are multifunctional modulators of the Barrett's carcinogenesis.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2010, Volume: 61, Issue:2

    Topics: Adenocarcinoma; Barrett Esophagus; CDX2 Transcription Factor; Cell Line, Tumor; Cyclooxygenase 2; Deoxycholic Acid; DNA Glycosylases; Down-Regulation; Esophageal Neoplasms; Gene Expression Regulation, Neoplastic; Homeodomain Proteins; Humans; NF-kappa B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Up-Regulation; Ursodeoxycholic Acid

2010
Combinatorial chemoprevention reveals a novel smoothened-independent role of GLI1 in esophageal carcinogenesis.
    Cancer research, 2010, Sep-01, Volume: 70, Issue:17

    Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Aspirin; Barrett Esophagus; Cell Growth Processes; Cyclin-Dependent Kinase 2; Disease Models, Animal; Down-Regulation; Esophageal Neoplasms; Humans; Oncogene Proteins; Promoter Regions, Genetic; Protein Binding; Rats; Trans-Activators; Transfection; Ursodeoxycholic Acid; Zinc Finger Protein GLI1

2010
Deoxycholic acid causes DNA damage while inducing apoptotic resistance through NF-κB activation in benign Barrett's epithelial cells.
    American journal of physiology. Gastrointestinal and liver physiology, 2011, Volume: 301, Issue:2

    Topics: Aged; Analysis of Variance; Animals; Apoptosis; Barrett Esophagus; Cell Line; Cell Transformation, Neoplastic; Deoxycholic Acid; DNA Damage; Epithelial Cells; Histones; Humans; I-kappa B Proteins; Male; Middle Aged; NF-kappa B; NF-KappaB Inhibitor alpha; Rats; Reactive Nitrogen Species; Reactive Oxygen Species; Signal Transduction; Ursodeoxycholic Acid

2011
Bile acid exposure up-regulates tuberous sclerosis complex 1/mammalian target of rapamycin pathway in Barrett's-associated esophageal adenocarcinoma.
    Cancer research, 2008, Apr-15, Volume: 68, Issue:8

    Topics: Adenocarcinoma; Barrett Esophagus; Bile Acids and Salts; Cell Division; Chenodeoxycholic Acid; Esophageal Neoplasms; Gastroesophageal Reflux; Gene Expression Regulation, Neoplastic; Humans; Inflammation; NF-kappa B; Nitriles; Protein Kinases; RNA, Small Interfering; Sirolimus; Sulfones; TOR Serine-Threonine Kinases; Tuberous Sclerosis Complex 1 Protein; Tumor Suppressor Proteins; Ursodeoxycholic Acid

2008
The effect of oral administration of ursodeoxycholic acid and high-dose proton pump inhibitors on the histology of Barrett's esophagus.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2008, Volume: 21, Issue:4

    Topics: Administration, Oral; Barrett Esophagus; Cholagogues and Choleretics; Female; Humans; Male; Middle Aged; Prospective Studies; Proton Pump Inhibitors; Ursodeoxycholic Acid

2008