uroporphyrinogen iii has been researched along with Porphyria Cutanea Tarda in 4 studies
Uroporphyrinogens: Porphyrinogens which are intermediates in heme biosynthesis. They have four acetic acid and four propionic acid side chains attached to the pyrrole rings. Uroporphyrinogen I and III are formed from polypyrryl methane in the presence of uroporphyrinogen III cosynthetase and uroporphyrin I synthetase, respectively. They can yield uroporphyrins by autooxidation or coproporphyrinogens by decarboxylation.
Porphyria Cutanea Tarda: An autosomal dominant or acquired porphyria due to a deficiency of UROPORPHYRINOGEN DECARBOXYLASE in the LIVER. It is characterized by photosensitivity and cutaneous lesions with little or no neurologic symptoms. Type I is the acquired form and is strongly associated with liver diseases and hepatic toxicities caused by alcohol or estrogenic steroids. Type II is the familial form.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acetone was not an inducer of hepatic CYP1A2 in the wild-type mice." | 1.31 | Relative roles of CYP2E1 and CYP1A2 in mouse uroporphyria caused by acetone. ( Bement, WJ; Dalton, TP; Gonzalez, FJ; Gorman, N; Nebert, DW; Sinclair, JF; Sinclair, PR; Szakacs, J; Walton, HS, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arch, DD | 1 |
| Bergeron, M | 1 |
| Hathaway, L | 1 |
| Kushner, JP | 3 |
| Phillips, JD | 3 |
| Franklin, MR | 3 |
| Bergonia, HA | 1 |
| Reilly, CA | 1 |
| Jackson, LK | 1 |
| Bunting, M | 1 |
| Thomas, KR | 1 |
| Levy, JE | 1 |
| Andrews, NC | 1 |
| Sinclair, PR | 1 |
| Gorman, N | 1 |
| Walton, HS | 1 |
| Bement, WJ | 1 |
| Szakacs, J | 1 |
| Gonzalez, FJ | 1 |
| Dalton, TP | 1 |
| Nebert, DW | 1 |
| Sinclair, JF | 1 |
4 other studies available for uroporphyrinogen iii and Porphyria Cutanea Tarda
| Article | Year |
|---|---|
Longitudinal study of a mouse model of familial porphyria cutanea tarda.
Topics: Animals; Cytochrome P-450 Enzyme System; Disease Models, Animal; Female; Genotype; Glutathione Trans | 2009 |
A porphomethene inhibitor of uroporphyrinogen decarboxylase causes porphyria cutanea tarda.
Topics: Animals; Chromatography, High Pressure Liquid; Cytosol; Humans; Liver; Liver Extracts; Mass Spectrom | 2007 |
A mouse model of familial porphyria cutanea tarda.
Topics: Aminolevulinic Acid; Animals; Cloning, Molecular; Coproporphyrinogens; Disease Models, Animal; Enzym | 2001 |
Relative roles of CYP2E1 and CYP1A2 in mouse uroporphyria caused by acetone.
Topics: Acetone; Aminolevulinic Acid; Animals; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2E1; Cytochrome | 2000 |