uroporphyrinogen iii has been researched along with Porphyria, Acute Intermittent in 2 studies
Uroporphyrinogens: Porphyrinogens which are intermediates in heme biosynthesis. They have four acetic acid and four propionic acid side chains attached to the pyrrole rings. Uroporphyrinogen I and III are formed from polypyrryl methane in the presence of uroporphyrinogen III cosynthetase and uroporphyrin I synthetase, respectively. They can yield uroporphyrins by autooxidation or coproporphyrinogens by decarboxylation.
Porphyria, Acute Intermittent: An autosomal dominant porphyria that is due to a deficiency of HYDROXYMETHYLBILANE SYNTHASE in the LIVER, the third enzyme in the 8-enzyme biosynthetic pathway of HEME. Clinical features are recurrent and life-threatening neurologic disturbances, ABDOMINAL PAIN, and elevated level of AMINOLEVULINIC ACID and PORPHOBILINOGEN in the urine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We aimed to treat severe acute intermittent porphyria in a 19-year-old woman by liver transplantation." | 1.32 | Liver transplantation as a cure for acute intermittent porphyria. ( Badminton, MN; Bramhall, SR; Elder, GH; Elias, E; Orug, T; Rhodes, JM; Soonawalla, ZF, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Soonawalla, ZF | 1 |
| Orug, T | 1 |
| Badminton, MN | 1 |
| Elder, GH | 1 |
| Rhodes, JM | 1 |
| Bramhall, SR | 1 |
| Elias, E | 1 |
| Di Pierro, E | 1 |
| Brancaleoni, V | 1 |
| Cappellini, MD | 1 |
2 other studies available for uroporphyrinogen iii and Porphyria, Acute Intermittent
| Article | Year |
|---|---|
Liver transplantation as a cure for acute intermittent porphyria.
Topics: Adult; Aminolevulinic Acid; Female; Follow-Up Studies; Humans; Liver Transplantation; Porphyria, Acu | 2004 |
Gene symbol: HMBS. Disease: Porphyria, acute intermittent.
Topics: Base Sequence; Frameshift Mutation; Gene Deletion; Humans; Porphyria, Acute Intermittent; Uroporphyr | 2005 |