Page last updated: 2024-08-17

uridine diphosphate and Disease Models, Animal

uridine diphosphate has been researched along with Disease Models, Animal in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (10.00)29.6817
2010's14 (70.00)24.3611
2020's4 (20.00)2.80

Authors

AuthorsStudies
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1
Arena, P; Attanasio, S; Boffa, I; Brunetti-Pierri, N; Cuomo, P; D'Alessio, AM; De Angelis, A; Desviat, LR; Ferenbach, AT; Häberle, J; Lipshutz, GS; Makris, G; Martínez-Pizarro, A; Motta, A; Nitzahn, M; Nusco, E; Paris, D; Pravata, VM; Richard, E; Rüfenacht, V; Soria, LR; van Aalten, DMF1
Arumugam, TV; Jo, DG; Lai, MKP; Park, J1
Belosludtseva, NV; Bulion, VV; Evdokimova, NR; Krylova, IB; Mironova, GD; Rodionova, OM; Selina, EN; Shigaeva, MI1
Harada, T; Iwata, T; Kashiwagi, K; Koizumi, S; Namekata, K; Ohno, N; Robaye, B; Shinozaki, Y; Takeda, A1
Akerley, BJ; Jackson, MD; Wong, SM1
Ayata, CK; Bode, C; Cicko, S; Dufner, B; Grimm, M; Hergeth, S; Hoppe, N; Idzko, M; Marchini, T; Michel, NA; Peikert, A; Reinöhl, J; Schulte, L; Stachon, P; von zur Muhlen, C; Wolf, D; Zirlik, A1
Schiffmann, R1
Aerts, JM; Archer, J; Cox, TM; Dekker, N; Karlsson, S; Pavlova, EV; Wang, S1
Du, B; Li, R; Liu, M; Ma, X; Qian, M; Tan, B; Yan, Y; Zhang, N; Zhang, Z1
Bremser, S; Brüning, JC; Evers, N; Hinze, Y; Idzko, M; Kloppenburg, P; Paeger, L; Steculorum, SM1
Du, B; Liu, M; Lv, Z; Qian, M; Qin, J; Ren, H; Tan, B; Zhang, G; Zhang, X1
Abraham, P; Ayer, A; Billaud, M; Boeynaems, JM; de Wit, C; Grimaud, L; Henrion, D; Isakson, BE; Kauffenstein, G; Kwak, BR; Loufrani, L; Monyer, H; Procaccio, V; Prunier, F; Robaye, B; Rousseau, P; Roy, C; Tamareille, S; Toutain, B1
Hayashi, Y; Liu, Y; Nakanishi, H; Takayama, F; Wu, Z1
Chen, LL; Du, B; Jiang, WZ; Qian, M; Ren, H; Shi, JP; Wang, SY; Zhang, XY; Zhao, YH1
Bremser, S; Brüning, JC; Engström Ruud, L; Evers, N; Kloppenburg, P; Paeger, L; Steculorum, SM; Timper, K1
Matsumoto, T; Tostes, RC; Webb, RC1
Alam, SN; Hamarneh, SR; Hodin, RA; Hohmann, E; Kaliannan, K; Malo, MS; Malo, NS; Millán, JL; Moaven, O; Mohamed, MM; Moss, AK; Muhammad, N; Narisawa, S; Patel, P; Ramasamy, S; Teshager, A; Warren, HS; Yammine, H1
Minami, M; Nakagawa, T; Okada, M; Satoh, M1
Atucha, N; De Rycker, M; García-Estañ, J; Iyu, D; Soler, A1

Reviews

2 review(s) available for uridine diphosphate and Disease Models, Animal

ArticleYear
O-GlcNAcylation as a Therapeutic Target for Alzheimer's Disease.
    Neuromolecular medicine, 2020, Volume: 22, Issue:2

    Topics: Acetylglucosamine; Aged; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Antigens, Neoplasm; Brain; Diabetes Mellitus, Type 2; Disease Models, Animal; Glucose; Glutamine-Fructose-6-Phosphate Transaminase (Isomerizing); Glycosylation; Hexosamines; Histone Acetyltransferases; Humans; Hyaluronoglucosaminidase; Insulin Resistance; Molecular Structure; Nerve Tissue Proteins; Neurodegenerative Diseases; Neuroprotective Agents; Phosphorylation; Protein Isoforms; Protein Processing, Post-Translational; Stroke; tau Proteins; Uridine Diphosphate; Uridine Diphosphate N-Acetylgalactosamine

2020
The consequences of genetic and pharmacologic reduction in sphingolipid synthesis.
    Journal of inherited metabolic disease, 2015, Volume: 38, Issue:1

    Topics: Animals; Asthma; Atherosclerosis; Diabetes Mellitus; Disease Models, Animal; Glucose; Glucosyltransferases; Humans; Lipid Metabolism; Lysosomes; Mice; Polycystic Kidney Diseases; Serine C-Palmitoyltransferase; Sphingolipidoses; Sphingolipids; Uridine Diphosphate

2015

Other Studies

18 other study(ies) available for uridine diphosphate and Disease Models, Animal

ArticleYear
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020
O-GlcNAcylation enhances CPS1 catalytic efficiency for ammonia and promotes ureagenesis.
    Nature communications, 2022, 09-05, Volume: 13, Issue:1

    Topics: Acetylglucosamine; Ammonia; Animals; Biocatalysis; Carbamoyl-Phosphate Synthase (Ammonia); Disease Models, Animal; Glycosylation; Humans; Hyperammonemia; Mammals; Mice; N-Acetylglucosaminyltransferases; Propionic Acidemia; Protein Processing, Post-Translational; Urea; Uridine Diphosphate

2022
Uridine treatment prevents myocardial injury in rat models of acute ischemia and ischemia/reperfusion by activating the mitochondrial ATP-dependent potassium channel.
    Scientific reports, 2021, 08-20, Volume: 11, Issue:1

    Topics: Acute Disease; Adenosine Triphosphate; Animals; Antioxidants; Arrhythmias, Cardiac; Disease Models, Animal; Lipid Peroxidation; Male; Myocardial Reperfusion Injury; Myocardium; Potassium Channels; Rats, Wistar; Tachycardia; Uridine; Uridine Diphosphate; Uridine Triphosphate; Ventricular Fibrillation

2021
Purinergic dysregulation causes hypertensive glaucoma-like optic neuropathy.
    JCI insight, 2017, 10-05, Volume: 2, Issue:19

    Topics: Aging; Animals; Aqueous Humor; Ciliary Body; Disease Models, Animal; Dose-Response Relationship, Drug; Glaucoma; Intraocular Pressure; Mice, Knockout; Optic Nerve Diseases; Receptors, Purinergic P2; Retinal Ganglion Cells; Signal Transduction; Uridine Diphosphate

2017
Suppression of Alternative Lipooligosaccharide Glycosyltransferase Activity by UDP-Galactose Epimerase Enhances Murine Lung Infection and Evasion of Serum IgM.
    Frontiers in cellular and infection microbiology, 2019, Volume: 9

    Topics: Animals; Bacterial Proteins; Biofilms; Complement System Proteins; Disease Models, Animal; Gene Deletion; Gene Expression; Glycosyltransferases; Haemophilus Infections; Haemophilus influenzae; Humans; Immune Evasion; Immunoglobulin M; Lipopolysaccharides; Lung; Mice; UDPglucose 4-Epimerase; Uridine Diphosphate; Uridine Diphosphate Galactose; Uridine Diphosphate Glucose; Virulence

2019
P2Y6 deficiency limits vascular inflammation and atherosclerosis in mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2014, Volume: 34, Issue:10

    Topics: Animals; Aorta; Aortic Diseases; Atherosclerosis; Bone Marrow Transplantation; Cholesterol, Dietary; Disease Models, Animal; Inflammation; Inflammation Mediators; Leukocyte Rolling; Macrophages; Mice; Mice, Knockout; Plaque, Atherosclerotic; Receptors, LDL; Receptors, Purinergic P2; Signal Transduction; Time Factors; Transendothelial and Transepithelial Migration; Uridine Diphosphate

2014
Inhibition of UDP-glucosylceramide synthase in mice prevents Gaucher disease-associated B-cell malignancy.
    The Journal of pathology, 2015, Volume: 235, Issue:1

    Topics: Animals; Disease Models, Animal; Female; Gaucher Disease; Glucosyltransferases; Lymphoma, B-Cell; Male; Mice; Pyrrolidines; Uridine Diphosphate

2015
Extracellular UDP and P2Y6 function as a danger signal to protect mice from vesicular stomatitis virus infection through an increase in IFN-β production.
    Journal of immunology (Baltimore, Md. : 1950), 2014, Nov-01, Volume: 193, Issue:9

    Topics: Activating Transcription Factor 2; Animals; Apoptosis; Cell Line; Cells, Cultured; Connexins; Disease Models, Animal; Female; Gap Junctions; Gene Expression; Humans; Interferon-beta; JNK Mitogen-Activated Protein Kinases; Macrophages; Mice; Mice, Knockout; Models, Biological; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-jun; Receptors, Purinergic P2; Signal Transduction; Uridine Diphosphate; Vesicular Stomatitis; Vesiculovirus; Virus Replication

2014
Hypothalamic UDP Increases in Obesity and Promotes Feeding via P2Y6-Dependent Activation of AgRP Neurons.
    Cell, 2015, Sep-10, Volume: 162, Issue:6

    Topics: Agouti-Related Protein; Animals; Appetite Regulation; Disease Models, Animal; Hypothalamus; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Obesity; Receptors, Purinergic P2; Uridine Diphosphate

2015
TLR-Activated Gap Junction Channels Protect Mice against Bacterial Infection through Extracellular UDP Release.
    Journal of immunology (Baltimore, Md. : 1950), 2016, Feb-15, Volume: 196, Issue:4

    Topics: Animals; Blotting, Western; Connexin 43; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Escherichia coli Infections; Female; Gap Junctions; Immunity, Innate; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Real-Time Polymerase Chain Reaction; Signal Transduction; Toll-Like Receptor 4; Toll-Like Receptors; Uridine Diphosphate

2016
Central Role of P2Y6 UDP Receptor in Arteriolar Myogenic Tone.
    Arteriosclerosis, thrombosis, and vascular biology, 2016, Volume: 36, Issue:8

    Topics: Adenosine Triphosphatases; Animals; Arterioles; Blood Pressure; Calcium Signaling; Cells, Cultured; Connexin 43; Disease Models, Animal; Dose-Response Relationship, Drug; Genotype; Heart Failure; Hydrolysis; Mechanotransduction, Cellular; Mesentery; Mice, Knockout; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Myocardial Infarction; Myocytes, Smooth Muscle; Myosin Light Chains; Phenotype; Phosphorylation; Purinergic P2X Receptor Agonists; Receptors, Purinergic P2; Receptors, Purinergic P2X7; rho GTP-Binding Proteins; rhoA GTP-Binding Protein; Uridine Diphosphate; Vasoconstriction; Vasoconstrictor Agents

2016
Diurnal dynamic behavior of microglia in response to infected bacteria through the UDP-P2Y6 receptor system.
    Scientific reports, 2016, 07-21, Volume: 6

    Topics: Animals; Brain; Cell Surface Extensions; Circadian Rhythm; Disease Models, Animal; Meningoencephalitis; Mice, Inbred C57BL; Microglia; Porphyromonas gingivalis; Receptors, Purinergic P2; Uridine Diphosphate

2016
P2Y6 contributes to ovalbumin-induced allergic asthma by enhancing mast cell function in mice.
    Oncotarget, 2016, Sep-20, Volume: 7, Issue:38

    Topics: Animals; Asthma; Bone Marrow Cells; Bronchoalveolar Lavage Fluid; Chemotaxis; Cytokines; Disease Models, Animal; Hypersensitivity; Immunoglobulin E; Inflammation; Interleukin-4; Mast Cells; Mice; Mice, Inbred C57BL; Ovalbumin; Phenotype; Real-Time Polymerase Chain Reaction; Receptors, Purinergic P2; Signal Transduction; Uridine Diphosphate

2016
Inhibition of P2Y6 Signaling in AgRP Neurons Reduces Food Intake and Improves Systemic Insulin Sensitivity in Obesity.
    Cell reports, 2017, 02-14, Volume: 18, Issue:7

    Topics: Agouti-Related Protein; Animals; Diet; Disease Models, Animal; Eating; Feeding Behavior; Hyperphagia; Insulin; Insulin Resistance; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Neurons; Obesity; Receptors, Purinergic P2; Signal Transduction; Uridine Diphosphate

2017
Alterations in vasoconstrictor responses to the endothelium-derived contracting factor uridine adenosine tetraphosphate are region specific in DOCA-salt hypertensive rats.
    Pharmacological research, 2012, Volume: 65, Issue:1

    Topics: Adenosine Triphosphate; Animals; Aorta, Thoracic; Arteries; Basilar Artery; Desoxycorticosterone; Dinucleoside Phosphates; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Femoral Artery; Hypertension; Male; Mesenteric Arteries; Purinergic P2 Receptor Agonists; Rats; Rats, Wistar; Receptors, Purinergic P2; Sodium Chloride, Dietary; Uridine Diphosphate; Uridine Triphosphate; Vasoconstriction; Vasoconstrictor Agents

2012
Intestinal alkaline phosphatase inhibits the proinflammatory nucleotide uridine diphosphate.
    American journal of physiology. Gastrointestinal and liver physiology, 2013, Mar-15, Volume: 304, Issue:6

    Topics: Alkaline Phosphatase; Animals; Bacterial Proteins; Cells, Cultured; Disease Models, Animal; Humans; Inflammation Mediators; Inflammatory Bowel Diseases; Interleukin-8; Intestinal Mucosa; Intestine, Small; Lipopolysaccharides; Mice; Mice, Knockout; Receptors, Purinergic P2; Uridine Diphosphate

2013
Analgesic effects of intrathecal administration of P2Y nucleotide receptor agonists UTP and UDP in normal and neuropathic pain model rats.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:1

    Topics: Adenosine Triphosphate; Analgesics; Animals; Disease Models, Animal; Hot Temperature; Injections, Spinal; Male; Neuralgia; Pain; Posture; Pressure; Purinergic P2 Receptor Agonists; Rats; Rats, Sprague-Dawley; Time Factors; Uridine; Uridine Diphosphate; Uridine Monophosphate; Uridine Triphosphate

2002
Altered calcium regulation in freshly isolated aortic smooth muscle cells from bile duct-ligated rats: role of nitric oxide.
    Cell calcium, 2003, Volume: 33, Issue:2

    Topics: Adenosine Triphosphate; Animals; Aorta; Bile Ducts; Calcium; Calcium Signaling; Cells, Cultured; Cholestasis; Disease Models, Animal; Fura-2; Hypotension; Liver Cirrhosis, Experimental; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Reaction Time; Regional Blood Flow; Uridine Diphosphate; Vasoconstriction

2003