uridine has been researched along with Neoplasms in 117 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 75 (64.10) | 18.7374 |
| 1990's | 13 (11.11) | 18.2507 |
| 2000's | 8 (6.84) | 29.6817 |
| 2010's | 16 (13.68) | 24.3611 |
| 2020's | 5 (4.27) | 2.80 |
| Authors | Studies |
|---|---|
| Cookson, V; Hanna, BMF; Helleday, T; Herr, P; Mayr, F; Mortusewicz, O; Walter, M | 1 |
| Gao, H; Pang, GZ; Rong, SQ; Wang, YX; Zhao, YH; Zhou, D | 1 |
| Chen, R; Dou, J; Huang, J; Shu, Z; Wang, Y; Yu, J; Yuan, H; Zhang, H; Zhao, X; Zhou, A | 1 |
| Leung, M; Rogers, JE; Shureiqi, I | 1 |
| Bruch, A; Glatt, S; Klassen, R; Schaffrath, R; Sokołowski, M | 1 |
| Aglietta, M; Bonzano, A; Cagnazzo, C; Depetris, I; Filippi, R; Leone, F; Marino, D | 1 |
| Brutcher, E; Christensen, D; Hennessey Smith, M; Koutlas, JB; Sellers, JB; Thompson, J; Timmons, T | 1 |
| Peters, GJ | 1 |
| Robert, J | 1 |
| He, S; Jiang, Y; Pu, K; Xie, C | 1 |
| Amylidi, AL; Angelaki, A; Aravantinos, G; Boumpoucheropoulos, S; Fildissis, G; Lampropoulou, DI; Laschos, K; Nanou, E; Nasioulas, G; Papadopoulou, E; Soupos, N; Zidianakis, V | 1 |
| D'Errico, G; Irace, C; Mangiapia, G; Montesarchio, D; Musumeci, D; Paduano, L; Santamaria, R; Vitiello, G | 1 |
| Begley, TJ; Begley, U; Clark, R; Dedon, PC; Dziergowska, A; Endres, L; Gu, C; Małkiewicz, A; Melendez, JA | 1 |
| Berridge, G; Goldin, R; Kessler, BM; Kriaucionis, S; Pugh, KM; Thézénas, ML; Zauri, M | 1 |
| Cai, C; Cao, D; Cao, Z; Chen, X; Huang, D; Ma, J; Zhang, X; Zhou, B | 1 |
| Chen, ZF; Cheng, KG; Huang, JY; Liu, J; Su, CH; Zheng, YT | 1 |
| Al-Ghamdi, M; Al-Saif, M; Al-Souhibani, N; Al-Yahya, S; Bakheet, T; Grépin, R; Győrffy, B; Hitti, E; Khabar, KS; Lánczky, A; Moghrabi, W; Pagès, G; Shoukri, MM | 1 |
| Bai, G; Beaver, JA; Charlab, R; Chen, XH; Cheng, J; Dinin, J; Dorff, SE; Ibrahim, A; Ison, G; Jin, R; Kim, G; Liu, Q; Marathe, A; McGuinn, WD; McKee, AE; Palmby, TR; Pazdur, R; Pierce, W; Sridhara, R; Stephens, O; Tang, S; Wang, Y; Ysern, X | 1 |
| Bamat, MK; Cartwright, TH; El-Rayes, BF; Fakih, MG; King, TR; Ma, WW; Posey, JA; Saif, MW; von Borstel, RW | 1 |
| Agrofoglio, LA; Breton, F; Delépée, R; Jégourel, D; Rolland, A; Vidal, R | 1 |
| Dinger, C; Kull, T; Kunkel, FH; Lepping, C; Morgenroth, A; Reske, SN; Urusova, EA; Zlatopolskiy, BD | 1 |
| Bremner, JB; Locke, JM; Pyne, SG; Ranson, M; Vine, KL | 1 |
| Bhuniya, S; Hong, KS; Jung, JH; Kim, JS; Lee, H; Lim, YT; Noh, YW; Park, J | 1 |
| DE BACKER, J | 1 |
| HOLMES, WL; PRUSOFF, WH; WELCH, AD | 1 |
| BURDON, RH; SMELLIE, RM | 1 |
| DEGERSTEDT, G; PONTIS, H; REICHARD, P | 1 |
| BROWN, RR; WOLBERG, WH | 1 |
| BROWN, DH; SILBERT, JE | 1 |
| ROBERTS, E; TANAKA, KK | 1 |
| ANDERSON, EP; BROCKMAN, RW | 1 |
| EASON, R; SMELLIE, RM | 1 |
| WELCH, AD | 1 |
| Cao, D; Pizzorno, G | 1 |
| Hrdlicka, PJ; Jepsen, JS; Wengel, J | 1 |
| Bayfield, MA; He, N; Hong, E; Jahchan, NS; Li, Q; Luo, K; Maraia, RJ; Zhou, Q | 1 |
| Cimino, F; Cimino, L; Colonna, A; Mazzacca, G; Russo, T; Salvatore, F | 1 |
| Knaus, EE; Lee, YW; Mercer, JR; Wiebe, LI | 1 |
| Jekunen, A; Vilpo, JA | 1 |
| Martin, DS; Sawyer, RC; Spiegelman, S; Stolfi, RL; Young, CW | 1 |
| Akiyama, S; Ichihashi, H; Kondo, T; Sakakibara, S; Watanabe, T | 1 |
| Mattern, J; Volm, M | 1 |
| Cimino, F; Colonna, A; Esposito, F; Russo, T; Salvatore, F | 1 |
| Au, JL; Danhauser, L; Luccioni, C; Rustum, YM | 1 |
| Willnow, U | 1 |
| Barlogie, B; Benjamin, RS; Bodey, GP; Burgess, MA; McCredie, KD; Stewart, DJ; Valdivieso, M | 1 |
| Buzaid, AC; Hait, WN; Marsh, JC; Murren, JR; Pizzorno, G; Poo, WJ; Ravikumar, TS; Strair, RK; Todd, M | 1 |
| Colofiore, J; Kemeny, N; Martin, D; Sawyer, R; Schneider, A; Seiter, K; Williams, L | 1 |
| Peters, GJ; Pinedo, HM; van Groeningen, CJ | 1 |
| Bertino, J; Casper, E; Christman, K; Colofiore, J; Kelsen, D; Martin, DS; Quan, V; Saltz, L; Schwartz, GK | 1 |
| Cai, J; Lee, CW | 1 |
| Bertino, J; Kelsen, DP; Martin, D; O'Neil, J; Saltz, L; Schwartz, G; Sung, MT; von Borstel, R | 1 |
| Lund, AE | 1 |
| Cao, D; Handschumacher, RE; Liu, M; Pizzorno, G; Russell, R | 1 |
| Baldwin, SA; Cass, CE; Karpinski, E; Mackey, JR; Smith, KM; Yao, SY; Young, JD | 1 |
| Jeanteur, P | 1 |
| Anant, S; Chester, A; Navaratnam, N; Scott, J | 1 |
| Cao, D; Handschumacher, RE; Leffert, JJ; Pizzorno, G; Russell, RL; Zhang, D | 1 |
| Hinderer, H; Kaufmann, M; Mattern, J; Volm, M; Wayss, K | 1 |
| Cadman, EC; Dix, DE; Handschumacher, RE | 1 |
| Benvenuto, JA; Loo, TL; Plunkett, W; Stewart, DJ | 1 |
| Grindey, GB; Mihich, E | 1 |
| Schmidt, CG; Seeber, S | 1 |
| Gifford, GE; Ostrove, JM | 1 |
| Burchenal, JH; Currie, VE; Krakoff, IH; Mackey, RW; Tan, CT; Wong, PP; Young, CW | 1 |
| Gordon, CS; Krakoff, IH; Kreis, W; Woodcock, TM | 1 |
| Dickson, JA; Suzangar, M | 1 |
| Germain, MJ; Gore, SS; Kirss, TA; Pauly, JL; Schuller, MG; Zelcer, AA | 1 |
| Smith, LH; Taylor, SA; Uziel, M | 1 |
| Levine, L; Stolbach, L; Waalkes, TP | 1 |
| Ahmann, DL; Chang, SY; Gehrke, CW; Lakings, DB; Moertel, CG; Tormey, DC; Waalkes, TP; Zumwalt, RW | 1 |
| Fuska, J; Fusková, A; Proksa, B | 1 |
| Bennett, BD; Gay, I; Morrison, GH; Zha, X | 1 |
| Dorr, RT | 1 |
| Laurensse, EJ; Nadal, JC; Peters, GJ; Pinedo, HM; Schwartsmann, G; van der Vijgh, WJ; van Groeningen, CJ | 1 |
| Kemeny, NE; Martin, DS; Schneider, A | 1 |
| Moriconi, WJ; Slavik, M; Taylor, S | 1 |
| Klubes, P; Leyland-Jones, B | 1 |
| Ishida, N; Itoh, K; Mizugaki, M | 1 |
| Guerrieri, A; Palmisano, F; Rotunno, T; Zambonin, PG | 1 |
| Laurensse, E; Leyva, A; Peters, GJ; Pinedo, HM; van Groeningen, CJ | 1 |
| Burchenal, JH; Fanucchi, MP; Fox, JJ; Leyland-Jones, B; Watanabe, KA; Young, CW | 1 |
| Abramson, I; Chan, TC; Howell, SB; Markman, M; Pfeifle, CE; Taetle, R | 1 |
| Benz, C; James, TL; Keniry, M; Shafer, RH | 1 |
| Bartlett, SE; Casson, AG; Ford, CH; Gallant, ME; Marsden, CH | 1 |
| Chan, TC; Cleary, S; Howell, SB; Markman, M | 2 |
| Ichihashi, H | 1 |
| Kraal, I; Leyva, A; Peters, GJ; Pinedo, HM; van Groeningen, CJ | 1 |
| Collins, JM; Fine, RL; Jenkins, JF; Kinsella, TJ; Klecker, RW; Strong, JM | 1 |
| Daidone, MG; Gasparini, G; Sanfilippo, O; Silvestrini, R; Zaffaroni, N | 1 |
| Goerttler, K; Kaufmann, M; Mattern, J; Volm, M; Wayss, K | 1 |
| Mattern, J; Volm, M; Wayss, K | 1 |
| Wolberg, WH | 2 |
| Brenner, L; Go, LT; Herbert, V; Tisman, G | 1 |
| Feinendegen, LE | 1 |
| Norpoth, K; Oberwittler, W; Witting, U; Wüst, GP | 1 |
| Schapira, F | 1 |
| Gelboin, HV | 1 |
| Beltz, RE; Hinshaw, DB; Jolley, WB; Waters, RN | 1 |
| Allen, A; Jacobson, A; Ramon, T; Wade, ME | 1 |
| Wüst, G | 1 |
| Hoshi, A; Kanai, T; Kanzawa, F; Kuretani, K; Yoshida, M | 1 |
| Covelli, I; Frati, L; Mozzi, R; Rossi, R | 1 |
| Hahn, GM; Little, JB | 1 |
| Dinsmore, SR; Mrochek, JE; Waalkes, TP | 1 |
| Wüst, GP | 1 |
| Kampmann, H; Mattern, J; Schuhmacher, J; Volm, M; Wayss, K; Zimmerer, J | 1 |
| Ghelelovitch, S | 1 |
| Humphrey, EW; Mizuno, NS | 1 |
| Inch, WR; McCredie, JA; Sutherland, RM | 1 |
| Rogers, WI; Wilson, JA | 1 |
| Galt, RM; Knock, FE; Oester, YT; Renaud, OV; Sylvester, R | 1 |
| Fabrikant, JI | 1 |
| Byfield, JE; Stein, JJ | 1 |
| Wenzel, M | 1 |
18 review(s) available for uridine and Neoplasms
| Article | Year |
|---|---|
Cooperativity between different tRNA modifications and their modification pathways.
Topics: Animals; Anticodon; Endoribonucleases; Eukaryotic Cells; Humans; Mitochondrial Diseases; Models, Molecular; Multiprotein Complexes; Neoplasms; Nervous System Diseases; Nucleic Acid Conformation; Protein Biosynthesis; RNA Processing, Post-Transcriptional; RNA Stability; RNA-Binding Proteins; RNA, Fungal; RNA, Neoplasm; RNA, Transfer; Saccharomyces cerevisiae Proteins; Schizosaccharomyces pombe Proteins; tRNA Methyltransferases; Uridine | 2018 |
Fluoropyrimidine-induced cardiotoxicity.
Topics: Acetates; Capecitabine; Cardiotoxicity; Cardiovascular Diseases; Drug Combinations; Fluorouracil; Humans; Neoplasms; Pyrimidines; Pyrrolidines; Quinazolines; Thiophenes; Thymine; Trifluridine; Uracil; Uridine | 2018 |
5-Fluorouracil and Capecitabine: Assessment and Treatment of Uncommon Early-Onset Severe Toxicities Associated With Administration.
Topics: Acetates; Adult; Aged; Antimetabolites, Antineoplastic; Capecitabine; Drug-Related Side Effects and Adverse Reactions; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasms; Patient Safety; Risk Assessment; Severity of Illness Index; Survival Analysis; Uridine | 2018 |
Fluoropyrimidine-induced toxicity and DPD deficiency.. A case report of early onset, lethal capecitabine-induced toxicity and mini review of the literature. Uridine triacetate: Efficacy and safety as an antidote. Is it accessible outside USA?
Topics: Acetates; Aged; Antidotes; Antimetabolites, Antineoplastic; Capecitabine; Dihydropyrimidine Dehydrogenase Deficiency; Female; Humans; Neoplasms; Uridine | 2020 |
FDA Approval: Uridine Triacetate for the Treatment of Patients Following Fluorouracil or Capecitabine Overdose or Exhibiting Early-Onset Severe Toxicities Following Administration of These Drugs.
Topics: Acetates; Animals; Antineoplastic Agents; Capecitabine; Clinical Trials as Topic; Drug Approval; Drug Evaluation, Preclinical; Fluorouracil; Humans; Neoplasms; Prescription Drug Overuse; Research Design; Treatment Outcome; United States; United States Food and Drug Administration; Uridine | 2016 |
Uridine phosophorylase: an important enzyme in pyrimidine metabolism and fluoropyrimidine activation.
Topics: Animals; Antimetabolites, Antineoplastic; Floxuridine; Fluorouracil; Gene Expression Regulation, Enzymologic; Humans; Neoplasms; Pyrimidines; Uridine; Uridine Phosphorylase | 2004 |
Clinical relevance of predictive tests for cancer chemotherapy.
Topics: Animals; Antineoplastic Agents; Cell Survival; Cells, Cultured; Drug Evaluation, Preclinical; Drug Resistance; Humans; Neoplasm Transplantation; Neoplasms; Nucleic Acids; Organ Culture Techniques; Thymidine; Transplantation, Heterologous; Uridine | 1982 |
Determinants of response to antimetabolites and their modulation by normal purine and pyrimidine metabolites.
Topics: Animals; Antimetabolites, Antineoplastic; Cytarabine; DNA, Neoplasm; Fluorodeoxyuridylate; Fluorouracil; Humans; Leukemia L1210; Neoplasms; Neoplasms, Experimental; Thymidine; Thymidylate Synthase; Uridine | 1981 |
RNA editing: cytidine to uridine conversion in apolipoprotein B mRNA.
Topics: Animals; APOBEC-1 Deaminase; Apolipoproteins B; Base Sequence; Catalytic Domain; Cytidine; Cytidine Deaminase; Genetic Therapy; Humans; Models, Molecular; Molecular Sequence Data; Neoplasms; Phylogeny; RNA Editing; RNA, Messenger; Sequence Alignment; Uridine | 2000 |
Homeostatic control of uridine and the role of uridine phosphorylase: a biological and clinical update.
Topics: Animals; Antineoplastic Agents; Biological Transport, Active; Fluorouracil; Gene Expression Regulation, Enzymologic; Genes, p53; Homeostasis; Humans; Neoplasms; Promoter Regions, Genetic; Subcellular Fractions; Uridine; Uridine Phosphorylase; Vimentin | 2002 |
Multiple basis of combination chemotherapy.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Antagonism; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Humans; Leucovorin; Mercaptopurine; Methotrexate; Neoplasms; Neoplasms, Experimental; Uridine | 1977 |
[On the problem of praetherapeutic sensitivity testing of human tumours based on incorporation studies of nucleic acid precursors in vitro (author's transl)].
Topics: Alkylating Agents; Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents; DNA, Neoplasm; Drug Interactions; Drug Therapy, Combination; Humans; In Vitro Techniques; Neoplasms; Nucleic Acid Precursors; RNA, Neoplasm; Thymidine; Uridine | 1977 |
A predictive in vitro assay for the sensitivity of human solid tumours to hyperthermia (42 degrees C) and its value in patient management.
Topics: Aged; Animals; Breast Neoplasms; Child; Child, Preschool; DNA, Neoplasm; Evaluation Studies as Topic; Female; Glycolysis; Hot Temperature; Humans; Hyperthermia, Induced; In Vitro Techniques; Leucine; Male; Mice; Middle Aged; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Oxygen Consumption; Rats; Thymidine; Transplantation, Heterologous; Uridine | 1976 |
Chemoprotectants for cancer chemotherapy.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Asparaginase; Cisplatin; Cyclophosphamide; Fluorouracil; Humans; Ifosfamide; Leucovorin; Mesna; Methotrexate; Neoplasms; Razoxane; Sulfhydryl Compounds; Uridine | 1991 |
Enhancement of the antitumor activity of 5-fluorouracil by uridine rescue.
Topics: Animals; Drug Therapy, Combination; Fluorouracil; Humans; Neoplasms; Uridine | 1989 |
Isozymes and cancer.
Topics: Acid Phosphatase; Alcohol Oxidoreductases; Aldehyde Oxidoreductases; Alkaline Phosphatase; Animals; Carcinoma, Hepatocellular; DNA Nucleotidyltransferases; Esterases; Fructose-Bisphosphatase; Fructose-Bisphosphate Aldolase; Glucosyltransferases; Glutaminase; Glycogen Synthase; Hexokinase; Humans; Isocitrate Dehydrogenase; Isoenzymes; L-Lactate Dehydrogenase; Liver Neoplasms; Malate Dehydrogenase; Mice; Neoplasms; Phosphotransferases; Pyruvate Kinase; Rats; Terminology as Topic; Thymidine Kinase; Transaminases; tRNA Methyltransferases; Uridine | 1973 |
Studies on the mechanism of microsomal hydroxylase induction and its role in carcinogen action.
Topics: Animals; Anthracenes; Benz(a)Anthracenes; Carbon Isotopes; Carcinogens; Cells, Cultured; Cricetinae; Cytidine; Dactinomycin; Electrophoresis; Enzyme Induction; Methylcholanthrene; Mice; Microsomes, Liver; Mixed Function Oxygenases; Neoplasms; Phenobarbital; Protein Biosynthesis; Rats; RNA; RNA Nucleotidyltransferases; Tritium; Uridine | 1972 |
Growth inhibitors rapidly inactivated by the host as potential antineoplastic agents in intra-arterial infusion chemotherapy.
Topics: Animals; Antimetabolites; Antineoplastic Agents; Bradykinin; Capillary Permeability; Cells, Cultured; Cytidine; Humans; Injections, Intra-Arterial; Mitosis; Neoplasms; Rats; RNA; Thymidine; Thymidine Kinase; Tritium; Uridine | 1972 |
5 trial(s) available for uridine and Neoplasms
| Article | Year |
|---|---|
Re-evaluation of Brequinar sodium, a dihydroorotate dehydrogenase inhibitor.
Topics: Aged; Animals; Antineoplastic Agents; Biphenyl Compounds; Dihydroorotate Dehydrogenase; Dose-Response Relationship, Drug; Female; Humans; Male; Mice; Middle Aged; Neoplasms; Oxidoreductases Acting on CH-CH Group Donors; Rats; Uridine | 2018 |
Biochemical modulation of 5-fluorouracil with brequinar: results of a phase I study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biphenyl Compounds; Drug Administration Schedule; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasms; Uridine | 1995 |
A phase I trial of a modified, dose intensive FAMTX regimen (high dose 5-fluorouracil+doxorubicin+high dose methotrexate+leucovorin) with oral uridine rescue.
Topics: Administration, Oral; Adult; Aged; Antidotes; Antineoplastic Combined Chemotherapy Protocols; Doxorubicin; Female; Fluorouracil; Humans; Leucovorin; Leukopenia; Male; Methotrexate; Middle Aged; Neoplasms; Neutropenia; Uridine | 1996 |
Phase I trial of PN401, an oral prodrug of uridine, to prevent toxicity from fluorouracil in patients with advanced cancer.
Topics: Acetates; Administration, Oral; Adult; Aged; Antimetabolites, Antineoplastic; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasms; Prodrugs; Uridine | 1997 |
Phase I evaluation of tetrahydrouridine combined with cytosine arabinoside.
Topics: Bone Marrow; Clinical Trials as Topic; Cytarabine; Drug Evaluation; Drug Synergism; Drug Therapy, Combination; Humans; Leukemia; Lymphoma; Middle Aged; Neoplasms; Nucleoside Deaminases; Pyrimidine Nucleosides; Tetrahydrouridine; Uridine | 1979 |
94 other study(ies) available for uridine and Neoplasms
| Article | Year |
|---|---|
NUDT22 promotes cancer growth through pyrimidine salvage.
Topics: Glucose; Humans; Neoplasms; Pyrimidines; Tumor Suppressor Protein p53; Uridine; Uridine Diphosphate | 2023 |
Mycoplasma infection of cancer cells enhances anti-tumor effect of oxidized methylcytidines.
Topics: Cytidine Deaminase; Deoxycytidine; Humans; Mycoplasma Infections; Neoplasms; Tetrahydrouridine; Uridine | 2023 |
SUMOylation modulates the LIN28A-let-7 signaling pathway in response to cellular stresses in cancer cells.
Topics: Animals; Carcinogenesis; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Lysine; Mice, Nude; MicroRNAs; Mutation; Neoplasms; Protein Binding; RNA-Binding Proteins; Signal Transduction; Stress, Physiological; Sumoylation; Uridine | 2020 |
Use of Uridine Triacetate to Reverse Severe Persistent Myelosuppression Following 5-fluorouracil Exposure in a Patient With a c.557A>G Heterozygous DPYD Variant.
Topics: Acetates; Fluorouracil; Humans; Neoplasms; Uridine | 2021 |
[5-FU: At last!]
Topics: Acetates; Antidotes; Antimetabolites, Antineoplastic; Dihydropyrimidine Dehydrogenase Deficiency; Fluorouracil; Humans; Neoplasms; Practice Guidelines as Topic; Pyrimidines; Uracil; Uridine | 2019 |
An Organic Afterglow Protheranostic Nanoassembly.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Dimerization; Drug Delivery Systems; Floxuridine; Hydrogen Peroxide; Infrared Rays; Luminescent Agents; Mice; Nanoparticles; Neoplasms; Polyethylene Glycols; Prodrugs; Theranostic Nanomedicine; Tissue Distribution; Tumor Microenvironment; Uridine | 2019 |
A new design for nucleolipid-based Ru(III) complexes as anticancer agents.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Coordination Complexes; Drug Design; Fatty Acids, Monounsaturated; Humans; Neoplasms; Phosphatidylcholines; Quaternary Ammonium Compounds; Ruthenium; Uridine | 2013 |
Alkbh8 Regulates Selenocysteine-Protein Expression to Protect against Reactive Oxygen Species Damage.
Topics: AlkB Homolog 8, tRNA Methyltransferase; Animals; DNA Damage; Fibroblasts; Gene Expression; Gene Expression Regulation; Glutathione Peroxidase; Mice; Mice, Inbred C57BL; Neoplasms; Oxidative Stress; Protein Processing, Post-Translational; Reactive Oxygen Species; RNA, Transfer; Selenocysteine; Thioredoxin-Disulfide Reductase; tRNA Methyltransferases; Uridine | 2015 |
CDA directs metabolism of epigenetic nucleosides revealing a therapeutic window in cancer.
Topics: 5-Methylcytosine; Animals; Cell Death; Cell Line, Tumor; Cytidine; Cytidine Deaminase; Cytosine; Deoxycytidine; DNA; DNA Damage; DNA-Directed DNA Polymerase; Epigenesis, Genetic; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Mice; Neoplasms; Nucleotides; Oxidation-Reduction; Phosphotransferases; Substrate Specificity; Up-Regulation; Uridine | 2015 |
Uridine homeostatic disorder leads to DNA damage and tumorigenesis.
Topics: Animals; Cell Transformation, Neoplastic; DNA Damage; Dose-Response Relationship, Drug; Genotype; Homeostasis; Humans; MCF-7 Cells; Mice, Knockout; Neoplasms; Phenotype; Phosphorylation; Time Factors; Tumor Suppressor Protein p53; Up-Regulation; Uracil; Uridine; Uridine Phosphorylase | 2016 |
Conjugation of Uridine with Oleanolic Acid Derivatives as Potential Antitumor Agents.
Topics: Antineoplastic Agents; Apoptosis; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Membrane Potential, Mitochondrial; Neoplasms; Oleanolic Acid; Uridine | 2016 |
Systematic Analysis of AU-Rich Element Expression in Cancer Reveals Common Functional Clusters Regulated by Key RNA-Binding Proteins.
Topics: Adenine; Cell Cycle Checkpoints; Cell Line, Tumor; ELAV-Like Protein 1; Gene Expression Regulation, Neoplastic; Humans; Neoplasms; Polyadenylation; RNA-Binding Proteins; RNA, Messenger; Tristetraprolin; Uridine | 2016 |
Emergency use of uridine triacetate for the prevention and treatment of life-threatening 5-fluorouracil and capecitabine toxicity.
Topics: Acetates; Antimetabolites, Antineoplastic; Capecitabine; Drug Overdose; Female; Fluorouracil; Humans; Male; Middle Aged; Neoplasms; Uridine | 2017 |
Molecularly imprinted polymer of 5-methyluridine for solid-phase extraction of pyrimidine nucleoside cancer markers in urine.
Topics: Acrylamide; Acrylates; Animals; Biomarkers; Chromatography, High Pressure Liquid; Dogs; Mass Spectrometry; Microscopy, Electron, Scanning; Molecular Imprinting; Neoplasms; Polymers; Propylene Glycols; Pyrimidine Nucleosides; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Uridine; Vinyl Compounds | 2008 |
Synthesis and biologic study of IV-14, a new ribonucleoside radiotracer for tumor visualization.
Topics: Animals; Biological Transport; Cell Line, Tumor; Cell Transformation, Neoplastic; Female; Humans; Intracellular Space; Iodine Radioisotopes; Male; Mice; Neoplasms; Radioactive Tracers; Radiochemistry; Radionuclide Imaging; Thymidine Phosphorylase; Time Factors; Tissue Distribution; Uridine; Uridine Kinase; Uridine Phosphorylase; Vinyl Compounds | 2009 |
Selective targeting of 2'-deoxy-5-fluorouridine to urokinase positive malignant cells in vitro.
Topics: Cell Line, Tumor; Humans; Neoplasms; Plasminogen Activator Inhibitor 2; Uridine; Urokinase-Type Plasminogen Activator | 2010 |
A DTTA-ligated uridine-quantum dot conjugate as a bimodal contrast agent for cellular imaging.
Topics: Animals; Cell Line, Tumor; Contrast Media; Flow Cytometry; Gadolinium; Magnetic Resonance Imaging; Mice; Microscopy, Fluorescence; Molecular Structure; Neoplasms; Organometallic Compounds; Quantum Dots; Uridine | 2012 |
[The new quarters of the Centrum voor Gezwelziekten at Ghent university].
Topics: Hospitals; Humans; Neoplasms; Universities; Uridine | 1952 |
Non-utilization of radioactive iodinated uracil, uridine, and orotic acid by animal tissues in vivo.
Topics: Neoplasms; Orotic Acid; Uracil; Uridine | 1953 |
The incorporation of uridine 5'-triphosphate into ribonucleic acid by enzyme fractions from Ehrlich ascites carcinoma cells.
Topics: Ascites; Biochemical Phenomena; Enzymes; Neoplasms; Nucleosides; Nucleotides; Polyphosphates; RNA; Uridine; Uridine Triphosphate | 1961 |
Uridine and deoxyuridine phosphorylases from Ehrlich ascites tumor.
Topics: Animals; Carcinoma, Ehrlich Tumor; DNA; Neoplasms; Pentosyltransferases; RNA; Uridine; Uridine Phosphorylase | 1961 |
Autoradiographic studies of in vitro incorporation of uridine and thymidine by human tumor tissue.
Topics: Autoradiography; In Vitro Techniques; Neoplasms; Research Design; Thymidine; Tissue Culture Techniques; Uridine | 1962 |
Enzymic synthesis of uridine diphosphate glucosamine and heparin from [14C]glucosamine by a mouse mast-cell tumor.
Topics: Biochemical Phenomena; Glucosamine; Heparin; Neoplasms; Nucleosides; Nucleotides; Uridine; Uridine Diphosphate | 1961 |
AUTORADIOGRAPHIC STUDIES OF MOUSE ASCITES TUMORS, C-1498 AND E.L.4, IN SUSCEPTIBLE (C57BL) A RESISTANT (B10.D2) MICE.
Topics: Amino Acids; Animals; Ascites; Autoradiography; Carcinoma, Ehrlich Tumor; DNA; DNA, Neoplasm; Metabolism; Mice; Mice, Inbred C57BL; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Proteins; Research; RNA; RNA, Neoplasm; Transplantation, Homologous; Uridine | 1964 |
FEEDBACK INHIBITION OF URIDINE KINASE BY CYTIDINE TRIPHOSPHATE AND URIDINE TRIPHOSPHATE.
Topics: Adenosine Triphosphate; Carbon Isotopes; Cytidine Triphosphate; Cytosine Nucleotides; Magnesium; Metabolism; Neoplasms; Nucleosides; Nucleotides; Oxidative Phosphorylation; Phosphotransferases; Radiometry; Research; Tissue Culture Techniques; Uracil Nucleotides; Uridine; Uridine Kinase; Uridine Triphosphate | 1964 |
THE INTRACELLULAR SITE OF FORMATION OF ENCEPHALOMYOCARDITIS VIRUS RIBONUCLEIC ACID.
Topics: Cytoplasm; Dactinomycin; Encephalomyocarditis virus; Metabolism; Neoplasms; Neoplasms, Experimental; Nucleosides; Pharmacology; Research; RNA; RNA Viruses; RNA, Neoplasm; RNA, Viral; Uracil Nucleotides; Uridine | 1965 |
[SOME MECHANISMS AND PROBLEMS OF SELECTIVE CHEMOTHERAPY].
Topics: Antineoplastic Agents; Drug Therapy; Humans; Methotrexate; Neoplasms; Nucleosides; Uracil; Uridine | 1965 |
Synthesis and biological evaluation of conformationally restricted and nucleobase-modified analogs of the anticancer compound 3'-C-ethynylcytidine (ECyd).
Topics: Antimetabolites; Antineoplastic Agents; Cell Line, Tumor; Chemistry, Pharmaceutical; Cytidine; Drug Design; Drug Screening Assays, Antitumor; Humans; Inhibitory Concentration 50; Models, Chemical; Neoplasms; Nucleic Acid Conformation; Uracil; Uridine | 2005 |
A La-related protein modulates 7SK snRNP integrity to suppress P-TEFb-dependent transcriptional elongation and tumorigenesis.
Topics: 3' Untranslated Regions; Animals; Autoantigens; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; HIV-1; Humans; Mammary Glands, Human; Neoplasms; Positive Transcriptional Elongation Factor B; Protein Binding; Ribonucleoproteins; Ribonucleoproteins, Small Nuclear; RNA Interference; RNA-Binding Proteins; SS-B Antigen; Transcription Factors; Transcription, Genetic; Uridine | 2008 |
Pseudouridine determination in blood serum as tumor marker.
Topics: Breast Neoplasms; Carcinoma, Hepatocellular; Chromatography, High Pressure Liquid; Colonic Neoplasms; Female; Humans; Leukemia, Lymphoid; Liver Neoplasms; Lung Neoplasms; Lymphoma; Neoplasms; Ovarian Neoplasms; Pseudouridine; Uridine | 1983 |
The synthesis of [36Cl]-, [82Br]- and [123I]-labelled 1-(3'-chloro-(bromo and iodo)-3'-deoxy-beta-D-arabinofuranosyl)uracil.
Topics: Arabinofuranosyluracil; Bromine; Chlorine; Humans; Iodine Radioisotopes; Isotope Labeling; Neoplasms; Radioisotopes; Radionuclide Imaging; Uridine | 1984 |
Reversal of deamination-related cytotoxicity of 5-methyl-2'-deoxycytidine by tetrahydrouridine in human leukemia cells.
Topics: Biotransformation; Cell Line; Cell Survival; Deoxycytidine; Humans; Kinetics; Neoplasms; Tetrahydrouridine; Uridine | 1984 |
Improved therapeutic index with sequential N-phosphonacetyl-L-aspartate plus high-dose methotrexate plus high-dose 5-fluorouracil and appropriate rescue.
Topics: Animals; Antineoplastic Agents; Aspartic Acid; Drug Therapy, Combination; Female; Fluorouracil; Leucovorin; Male; Methotrexate; Mice; Neoplasms; Organophosphorus Compounds; Phosphonoacetic Acid; Uridine | 1983 |
Application of radioactive precursors for the evaluation of sensitivity of cancer cells to anticancer drugs.
Topics: Adult; Aged; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cell Line; Cell Survival; DNA Repair; Drug Evaluation, Preclinical; Drug Resistance; Female; Gastrointestinal Neoplasms; Humans; Leucine; Male; Mice; Middle Aged; Neoplasm Transplantation; Neoplasms; Prognosis; Thymidine; Tritium; Uridine | 1984 |
Determination of pseudouridine and other nucleosides in human blood serum by high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Humans; Neoplasms; Nucleosides; Pseudouridine; Uridine | 1983 |
Comparative autoradiographic in vitro study of the incorporation of 3H-thymidine and 3H-uridine into the DNA and RNA of solid tumours in children.
Topics: Autoradiography; Child; DNA, Neoplasm; Humans; Neoplasms; RNA, Neoplasm; Thymidine; Uridine | 1980 |
Phase I study of 3-deazauridine in the treatment of adults with solid tumors.
Topics: 3-Deazauridine; Adult; Aged; Agranulocytosis; Drug Administration Schedule; Drug Evaluation; Female; Humans; Infusions, Parenteral; Leukocyte Count; Male; Middle Aged; Nausea; Neoplasms; Platelet Count; Thrombocytopenia; Uridine | 1980 |
Uridine allows dose escalation of 5-fluorouracil when given with N-phosphonacetyl-L-aspartate, methotrexate, and leucovorin.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Diarrhea; Drug Synergism; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Mouth Mucosa; Neoplasms; Phosphonoacetic Acid; Stomatitis; Uridine | 1993 |
Reversal of 5-fluorouracil-induced toxicity by oral administration of uridine.
Topics: Administration, Oral; Adult; Aged; Drug Therapy, Combination; Female; Fluorouracil; Humans; Leukopenia; Male; Middle Aged; Neoplasms; Thrombocytopenia; Uridine | 1993 |
Tamoxifen inhibits nitrobenzylthioinosine-sensitive equilibrative uridine transport in human MCF-7 breast cancer cells.
Topics: Animals; Breast Neoplasms; Carrier Proteins; Cells, Cultured; Humans; Kinetics; Membrane Proteins; Mice; Neoplasms; Nucleoside Transport Proteins; Nucleosides; Protein Binding; Sodium; Spleen; Tamoxifen; Thioinosine; Uridine | 1996 |
Quick cancer test developed.
Topics: Allopurinol; Antimetabolites; Biomarkers, Tumor; DNA; Humans; Neoplasms; Orotic Acid; Pyrimidines; Uridine | 1998 |
Expression, characterization, and detection of human uridine phosphorylase and identification of variant uridine phosphorolytic activity in selected human tumors.
Topics: Amino Acid Sequence; Animals; Antibody Specificity; Cloning, Molecular; DNA, Complementary; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Female; Humans; Kinetics; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Neoplasms; Rabbits; Sequence Homology, Amino Acid; Uracil; Uridine; Uridine Phosphorylase | 1998 |
Gemcitabine transport in xenopus oocytes expressing recombinant plasma membrane mammalian nucleoside transporters.
Topics: Animals; Antimetabolites, Antineoplastic; Biological Transport; Carrier Proteins; Cell Membrane; Deoxycytidine; Electrophysiology; Gemcitabine; Membrane Proteins; Neoplasms; Nucleosides; Oocytes; Recombinant Proteins; Sodium Channels; Uridine; Xenopus laevis | 1999 |
[Nutrition, genetic polymorphism, and cancer].
Topics: Colorectal Neoplasms; DNA; DNA Repair; Folic Acid; Genotype; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasms; Nutritional Physiological Phenomena; Oxidoreductases Acting on CH-NH Group Donors; Polymorphism, Genetic; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Risk Factors; Tetrahydrofolates; Thymidine; Uridine | 2000 |
Sensitivity tests of tumors to cytostatic agents. II. Investigation on human tumors.
Topics: Antineoplastic Agents; Autoradiography; Breast Neoplasms; Cell Count; Cell Division; Culture Techniques; Dactinomycin; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Female; Fluorouracil; Gastrointestinal Neoplasms; Humans; Lung Neoplasms; Neoplasms; Nucleic Acids; Ovarian Neoplasms; Procarbazine; Uridine | 1975 |
Clinical, biological, and biochemical effect of pyrazofurin.
Topics: Adolescent; Adult; Aged; Amides; Animals; Carcinoma 256, Walker; Cell Division; Cell Line; Female; Humans; In Vitro Techniques; Leukemia, Experimental; Leukemia, Myeloid, Acute; Male; Mice; Middle Aged; Mouth Mucosa; Neoplasms; Orotic Acid; Pyrazoles; Pyrimidine Nucleotides; Ribonucleosides; Ribose; Uridine | 1978 |
High-pressure liquid chromatographic analysis of 3-deazauridine-5'-triphosphate in human cancer cells.
Topics: 3-Deazauridine; Brain Neoplasms; Chromatography, High Pressure Liquid; Humans; In Vitro Techniques; Leukemia, Lymphoid; Male; Middle Aged; Neoplasms; Neoplasms, Experimental; Nucleotides; Time Factors; Uridine; Uridine Triphosphate | 1979 |
Stimulation of RNA synthesis in L-929 cells by rabbit tumor necrosis factor.
Topics: Animals; BCG Vaccine; Cell Survival; Cells, Cultured; Corynebacterium; Cytotoxins; Dactinomycin; Endotoxins; Mice; Mycobacterium bovis; Necrosis; Neoplasms; Rabbits; RNA; Uridine | 1979 |
Tetrahydrouridine: Physiologic disposition and effect upon deamination of cytosine arabinoside in man.
Topics: Administration, Oral; Biological Availability; Cytarabine; Cytidine Deaminase; Deamination; Dose-Response Relationship, Drug; Drug Therapy, Combination; Half-Life; Humans; Injections, Intravenous; Neoplasms; Tetrahydrouridine; Uridine | 1977 |
Identification and comparative analysis of thymidine phosphorylase in the plasma of healthy subjects and cancer patients.
Topics: Humans; In Vitro Techniques; Neoplasms; Pentosyltransferases; Thymidine; Thymidine Phosphorylase; Thymine; Uracil; Uridine | 1977 |
Modified nucleosides in urine: selective removal and analysis.
Topics: Adenosine; Chromatography, Affinity; Glycols; Humans; Isomerism; Neoplasms; Ribonucleosides; RNA; Stereoisomerism; Uridine | 1976 |
Serum levels of N2, N2-dimethylguanosine and pseudouridine as determined by radioimmunoassay for patients with malignancy.
Topics: Antibody Specificity; Breast Neoplasms; Guanosine; Humans; Leukemia; Methylation; Neoplasms; Pseudouridine; Radioimmunoassay; Uridine | 1975 |
The urinary excretion of nucleosides of ribonucleic acid by patients with advanced cancer.
Topics: Chromatography, Gas; Guanosine; Humans; Inosine; Neoplasms; Pseudouridine; RNA; RNA, Transfer; tRNA Methyltransferases; Uridine | 1975 |
New potential cytotoxic and antitumor substances I. In vitro effect of bikaverin and its derivatives on cells of certain tumors.
Topics: Adenine; Animals; Carcinoma, Ehrlich Tumor; Cells, Cultured; DNA, Neoplasm; In Vitro Techniques; Leukemia; Neoplasms; RNA, Neoplasm; Sarcoma; Thymidine; Uridine; Valine; Xanthenes; Xanthones | 1975 |
Intracellular boron localization and uptake in cell cultures using imaging secondary ion mass spectrometry (ion microscopy) for neutron capture therapy for cancer.
Topics: Animals; Boron Compounds; Cryopreservation; Mass Spectrometry; Mice; Microscopy; Neoplasms; Neutrons; Phenylalanine; Tumor Cells, Cultured; Uridine | 1992 |
In vivo inhibition of the pyrimidine de novo enzyme dihydroorotic acid dehydrogenase by brequinar sodium (DUP-785; NSC 368390) in mice and patients.
Topics: Animals; Antineoplastic Agents; Biphenyl Compounds; Dihydroorotate Oxidase; Dose-Response Relationship, Drug; Humans; Lymphocytes; Mice; Mice, Inbred BALB C; Neoplasms; Oxidoreductases; Reference Values; Uridine | 1990 |
Phase I trial of PALA, methotrexate, fluorouracil, leucovorin, and uridine rescue in patients with advanced cancer. The use of uridine to decrease fluorouracil toxicity.
Topics: Adult; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Drug Evaluation; Female; Fluorouracil; Humans; Leucovorin; Male; Methotrexate; Middle Aged; Neoplasms; Phosphonoacetic Acid; Uridine | 1990 |
3-Deazauridine (NSC 126849): an interesting modulator of biochemical response.
Topics: 3-Deazauridine; Acute Disease; Animals; Antineoplastic Agents; Azacitidine; Cytarabine; Decitabine; Drug Evaluation; Drug Synergism; Galactosamine; Humans; Kinetics; Leukemia; Neoplasms; Thymidine; Uridine | 1986 |
Detection of elevated amounts of urinary pseudouridine in cancer patients by use of a monoclonal antibody.
Topics: Antibodies, Monoclonal; Antibody Specificity; Chromatography, High Pressure Liquid; Creatine; Enzyme-Linked Immunosorbent Assay; Health Status; Humans; Hybridomas; Leukemia; Lymphoma; Neoplasms; Pseudouridine; Uridine | 1989 |
Simultaneous determination of pseudouridine and creatinine in untreated urine by ion-pair liquid chromatography with diode-array ultraviolet detection.
Topics: Adult; Chromatography, High Pressure Liquid; Creatinine; Female; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Neoplasms; Pseudouridine; Spectrophotometry, Ultraviolet; Uridine | 1989 |
Reversal of 5-fluorouracil-induced myelosuppression by prolonged administration of high-dose uridine.
Topics: Aged; Bone Marrow; Female; Fluorouracil; Humans; Leukopenia; Male; Middle Aged; Neoplasms; Thrombocytopenia; Uridine | 1989 |
Phase I trial of 1-(2'-deoxy-2'-fluoro-1-beta-D-arabinofuranosyl)-5-methyluracil (FMAU).
Topics: Adult; Aged; Antineoplastic Agents; Arabinofuranosyluracil; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Central Nervous System Diseases; Drug Evaluation; Female; Humans; Leukocyte Count; Lung Neoplasms; Male; Middle Aged; Nausea; Neoplasms; Platelet Count; Uridine; Vomiting | 1985 |
Uridine pharmacokinetics in cancer patients.
Topics: Adult; Biological Availability; Bone Marrow; Female; Half-Life; Humans; Male; Middle Aged; Neoplasms; Pilot Projects; Uridine | 1988 |
Noninvasive spectroscopic analysis of fluoropyrimidine metabolism in cultured tumor cells.
Topics: Animals; Cells, Cultured; Fluorouracil; Humans; Leukemia, Myeloid, Acute; Magnetic Resonance Spectroscopy; Mice; Monitoring, Physiologic; Neoplasms; Sarcoma 180; Uridine | 1986 |
Efficacy and specificity of vindesine monoclonal anti-carcinoembryonic antigen conjugate with nine human cancer cell lines.
Topics: Antibodies, Monoclonal; Antibody Specificity; Carcinoembryonic Antigen; Cell Line; Colonic Neoplasms; Enzyme-Linked Immunosorbent Assay; Evaluation Studies as Topic; Fluorescent Antibody Technique; Humans; Lung Neoplasms; Neoplasms; Rectal Neoplasms; Uridine; Vindesine | 1987 |
Plasma uridine changes in cancer patients treated with the combination of dipyridamole and N-phosphonacetyl-L-aspartate.
Topics: Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Dipyridamole; Drug Evaluation; Female; Humans; Male; Middle Aged; Neoplasms; Organophosphorus Compounds; Phosphonoacetic Acid; Uridine | 1986 |
[Clinical application of chemosensitivity testing using radioactive precursors].
Topics: Adult; Aged; Antineoplastic Agents; Drug Evaluation, Preclinical; Humans; Middle Aged; Neoplasms; Thymidine; Tritium; Uridine | 1986 |
Clinical and pharmacokinetic studies of prolonged administration of high-dose uridine intended for rescue from 5-FU toxicity.
Topics: Aged; Body Temperature; Drug Administration Schedule; Female; Fluorouracil; Humans; Infusions, Parenteral; Kinetics; Male; Middle Aged; Neoplasms; Uracil; Uridine | 1986 |
Phase I trial of combination therapy of cancer with N-phosphonacetyl-L-aspartic acid and dipyridamole.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Dipyridamole; Drug Evaluation; Drug Synergism; Female; Gastrointestinal Diseases; Headache; Humans; Male; Middle Aged; Neoplasms; Organophosphorus Compounds; Phosphonoacetic Acid; Uridine | 1987 |
Clinical pharmacology of 5-iodo-2'-deoxyuridine and 5-iodouracil and endogenous pyrimidine modulation.
Topics: Chromatography, High Pressure Liquid; Deoxyuridine; Humans; Idoxuridine; Infusions, Parenteral; Neoplasms; Thymine; Uracil; Uridine | 1985 |
In vitro activity of alkylating agents on human tumors as measured by a short-term antimetabolic assay.
Topics: Alkylating Agents; Breast Neoplasms; Cells, Cultured; DNA, Neoplasm; Drug Evaluation, Preclinical; Evaluation Studies as Topic; Female; Humans; Lymphoma; Male; Neoplasms; Ovarian Neoplasms; RNA, Neoplasm; Testicular Neoplasms; Thymidine; Uridine | 1985 |
[Selective tumour chemotherapy using oncobiograms (author's transl)].
Topics: Animals; Antineoplastic Agents; Bleomycin; Cricetinae; Culture Techniques; Cytarabine; Dactinomycin; Daunorubicin; Doxorubicin; Drug Evaluation; Drug Resistance; Fluorouracil; Humans; Methods; Methotrexate; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Procarbazine; Radioisotopes; Rats; Scintillation Counting; Thymidine; Triaziquone; Uridine | 1974 |
[The effects of cytostatic agents on short-term cultures (3H-uridine incorporation) and tissue cultures (cell counts) from human tumors (author's transl)].
Topics: Antineoplastic Agents; Bleomycin; Cell Count; Cell Transformation, Neoplastic; Cells, Cultured; Cytarabine; Dactinomycin; Daunorubicin; Doxorubicin; Drug Evaluation, Preclinical; Female; Fluorouracil; Humans; In Vitro Techniques; Methods; Methotrexate; Neoplasms; Ovarian Neoplasms; Podophyllin; Suspensions; Time Factors; Triaziquone; Tritium; Uridine | 1974 |
Determinants of human tumor sensitivity to fluorinated pyrimidine chemotherapy.
Topics: DNA, Neoplasm; Floxuridine; Fluorouracil; Humans; In Vitro Techniques; Ligases; Neoplasm Metastasis; Neoplasms; Phosphotransferases; Thymidine; Thymidine Kinase; Uracil Nucleotides; Uridine | 1967 |
Inhibition by penicillamine of DNA and protein synthesis by human bone marrow.
Topics: Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Copper; Deoxyuridine; Depression, Chemical; DNA; Formates; Humans; Ilium; In Vitro Techniques; Iron; Neoplasms; Penicillamine; Perchlorates; Protein Biosynthesis; RNA; Serine; Stereoisomerism; Thymidine; Tritium; Uridine; Zinc | 1972 |
Biochemical approaches to prediction of response in solid tumors.
Topics: Adenocarcinoma; Antineoplastic Agents; Carbon Isotopes; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Cells, Cultured; Colonic Neoplasms; DNA, Neoplasm; Drug Resistance; Formates; Head and Neck Neoplasms; Humans; In Vitro Techniques; Liver Neoplasms; Neoplasm Metastasis; Neoplasms; Neoplasms, Experimental; Prognosis; Thymidine; Thymine; Tritium; Uridine | 1971 |
[Cellular aspects of radiosensitization].
Topics: Humans; Iodine Radioisotopes; Neoplasms; Radiation Effects; Radiation-Sensitizing Agents; Uridine | 1972 |
[In vitro effect of hyperthermia on the incorporation rate of nucleic acid precursors in tumours and normal tissues].
Topics: Adenocarcinoma, Mucinous; Animals; Carcinoma 256, Walker; Chick Embryo; Cricetinae; Embryo, Mammalian; Female; Fever; Humans; Liver; Liver Regeneration; Male; Mice; Neoplasms; Neoplasms, Experimental; Rats; Sarcoma, Experimental; Sigmoid Neoplasms; Spleen; Thymidine; Tritium; Uridine | 1973 |
In vitro studies of human tumor and embryonic tissue.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Count; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Cytological Techniques; Embryo, Mammalian; Female; Humans; Karyotyping; Lung Neoplasms; Methods; Mitosis; Neoplasms; Osteosarcoma; Ovarian Neoplasms; Time Factors; Tritium; Uridine; Uterine Cervical Neoplasms | 1973 |
[Methods and results of neoplasm sensitivity tests using cytostatic agents].
Topics: Antineoplastic Agents; Culture Techniques; Humans; Neoplasms; Thymidine; Tritium; Uridine | 1972 |
Specific inhibition of DNA synthesis by cyclocytidine.
Topics: Animals; Antineoplastic Agents; Carbon Isotopes; Cells, Cultured; Cyclization; Cytidine; Depression, Chemical; DNA; Leucine; Leukemia L1210; Mice; Neoplasms; Thymidine; Uridine | 1972 |
The mechanism of action of the epidermal growth factor. 3. Stimulation of the uptake of labeled precursors into RNA, DNA and proteins induced by EGF in isolated tumor cells.
Topics: Amino Acids; Animals; Carbon Isotopes; Carcinoma; Cell Line; Cells; DNA, Neoplasm; Epithelial Cells; Epithelium; Growth Substances; HeLa Cells; Humans; Kinetics; Male; Mice; Mouth Neoplasms; Neoplasm Proteins; Neoplasms; Peptides; RNA, Neoplasm; Spectrophotometry; Submandibular Gland; Thymidine; Time Factors; Tritium; Uridine | 1972 |
Plateau-phase cultures of mammalian cells: an in vitro model for human cancer.
Topics: Animals; Antineoplastic Agents; Carbon Isotopes; Cell Division; Cell Line; Cell Survival; Cells, Cultured; Contact Inhibition; Cricetinae; Culture Media; DNA; Humans; Leucine; Liver; Mitosis; Models, Biological; Neoplasms; Proteins; Radiation-Sensitizing Agents; RNA; Sulfhydryl Compounds; Thymidine; Time Factors; Tritium; Uridine; Valine | 1972 |
Urinary excretion by cancer patients of the nucleosides N-dimethylguanosine, 1-methylinosine, and pseudouridine.
Topics: Adolescent; Adult; Child; Chromatography, Gas; Chromatography, Ion Exchange; Female; Guanosine; Humans; Inosine; Male; Mass Spectrometry; Middle Aged; Neoplasms; Pseudouridine; Uridine | 1973 |
[Testing the sensitivity of malignant tumors to cytostatics in vitro and in vivo. Methods and clinical experiences].
Topics: Antineoplastic Agents; Culture Techniques; DNA, Neoplasm; Humans; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; RNA, Neoplasm; Thymidine; Tritium; Uridine | 1973 |
Incorporation of 131 iododeoxyuridine into the DNA of tumour-bearing rats after partial synchronization as a tool in scintigraphic tumour localization.
Topics: Animals; Cell Division; DNA; DNA, Neoplasm; Hydroxyurea; Iodine Radioisotopes; Male; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Radionuclide Imaging; Rats; Thoracic Neoplasms; Time Factors; Transplantation, Homologous; Uridine | 1974 |
[Comparison, in Drosophila, of the tumorigenic effects of uridine tritiated in the 5 position and in the 6 position].
Topics: Aging; Animals; Diet; Drosophila; Escherichia coli; Mutation; Neoplasms; Thymidine; Tritium; Uridine | 1969 |
Metabolism of 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide (NSC-45388) in human and animal tumor tissue.
Topics: Amides; Animals; Antineoplastic Agents; Carbohydrates; Carbon Isotopes; Chromatography, Thin Layer; DNA, Neoplasm; Humans; Imidazoles; Kinetics; Lung Neoplasms; Melanoma; Mice; Microsomes; Neoplasm Proteins; Neoplasms; Rectal Neoplasms; RNA, Neoplasm; Sarcoma 180; Spectrum Analysis; Thymidine; Thymus Neoplasms; Triazenes; Tritium; Uridine | 1972 |
Phytohemagglutinin (PHA)-induced transformation of lymphocytes from patients with cancer.
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; DNA; Female; Genital Neoplasms, Female; Hodgkin Disease; Humans; Infant; Lectins; Leukemia, Lymphoid; Lung Neoplasms; Lymphocyte Activation; Lymphocytes; Lymphoma, Non-Hodgkin; Middle Aged; Neoplasms; RNA; Thymidine; Tritium; Uridine | 1971 |
Determination of labile trifluoromethyl compounds with a fluoride--ion electrode: differential analysis of 5-trifluoromethyluracil and 5-trifluoromethyl-2'-deoxyuridine.
Topics: Carbon Isotopes; Chemical Phenomena; Chemistry; Electrodes; Fluorides; Fluorine; Humans; Hydrogen-Ion Concentration; Methods; Neoplasms; Uracil; Uridine | 1969 |
The use of selected sulfhydryl inhibitors in a preferential drug attack on cancer.
Topics: Adenocarcinoma; Adult; Agar; Animals; Antineoplastic Agents; Anus Neoplasms; Breast Neoplasms; Carcinoma, Squamous Cell; DNA; Dogs; Humans; Leucine; Leukocytes; Liver; Mice; Middle Aged; Neoplasms; Neoplasms, Experimental; Parotid Neoplasms; Proteins; Radioisotopes; Rectal Neoplasms; RNA; Sulfhydryl Compounds; Thoracic Neoplasms; Thymidine; Uridine | 1971 |
The kinetics of cellular proliferation in normal and malignant tissues: a review of methodology and the analysis of cell population kinetics in human tissues.
Topics: Adolescent; Adult; Aged; Autoradiography; Bronchial Neoplasms; Carbon Isotopes; Carcinoma, Squamous Cell; Cell Differentiation; Cell Division; Child; Culture Techniques; DNA, Neoplasm; Esophageal Neoplasms; Female; Humans; Hyperbaric Oxygenation; Kinetics; Laryngeal Diseases; Laryngeal Neoplasms; Larynx; Male; Methods; Middle Aged; Neoplasms; Papilloma; RNA, Neoplasm; Specimen Handling; Thymidine; Tritium; Uridine | 1971 |
A simple radiochemical assay of inhibition by chemotherapeutic agents of precursor incorporation into biopsy samples, effusions, and leukocyte preparations.
Topics: Amino Acids; Animals; Antineoplastic Agents; Biological Assay; Biopsy; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Carcinoma, Squamous Cell; Glycerol; Humans; Leukocytes; Methods; Neoplasms; Radiochemistry; Thymidine; Tritium; Uridine | 1968 |
[HTO-formation from tritium labelled compounds in vivo as proof of tritium incorporation].
Topics: Animals; Ascites; Estradiol; Female; Glycerol; Glycosuria; Hydrocortisone; Lactates; Neoplasms; Pregnancy; Rats; Testosterone; Thymidine; Tritium; Uridine | 1969 |