Page last updated: 2024-08-17

uridine and Myelodysplastic Syndromes

uridine has been researched along with Myelodysplastic Syndromes in 11 studies

Research

Studies (11)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (18.18)	24.3611
2020's	9 (81.82)	2.80

Authors

Authors	Studies
Griffiths, EA	1
Chen, H; de Claro, RA; Earp, J; Ehrlich, LA; Gehrke, BJ; Kim, N; Kitabi, E; Manning, ML; Norsworthy, KJ; Okusanya, OO; Pazdur, R; Subramaniam, S; Vallejo, J	1
Azab, M; Brandwein, J; Busque, L; DeZern, AE; Garcia-Manero, G; Griffiths, EA; Kantarjian, H; McCloskey, J; Michaelis, LC; O'Connell, C; Odenike, O; Oganesian, A; Roboz, GJ; Savona, MR; Steensma, DP; Wells, R; Yee, K	1
Ermolenko, DN; Feeney, CF; Kielkopf, CL; Laird, KM; Warnasooriya, C	1
Dhillon, S	1
Azab, M; Griffiths, EA; Oganesian, A; Thota, S	1
H Wei, A; Kipp, D	1
Cahill, K; Odenike, O; Patel, AA; Saygin, C	1
Amrein, PC; Azab, M; DeZern, AE; Faderl, S; Garcia-Manero, G; Harb, W; Kantarjian, H; Lowder, J; Michaelis, LC; Odenike, O; Oganesian, A; Savona, MR; Steensma, DP	1
Duchmann, M; Itzykson, R	1

Reviews

4 review(s) available for uridine and Myelodysplastic Syndromes

Article	Year
Decitabine/Cedazuridine: First Approval. Drugs, 2020, Volume: 80, Issue:13 Topics: Administration, Oral; Adult; Canada; Clinical Trials as Topic; Decitabine; Drug Approval; Drug Combinations; Drug Development; History, 21st Century; Humans; Leukemia, Myelomonocytic, Chronic; Myelodysplastic Syndromes; United States; United States Food and Drug Administration; Uridine	2020
Role of cedazuridine/decitabine in the management of myelodysplastic syndrome and chronic myelomonocytic leukemia. Future oncology (London, England), 2021, Volume: 17, Issue:16 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Decitabine; Disease Management; Drug Approval; Humans; Leukemia, Myelomonocytic, Chronic; Myelodysplastic Syndromes; Treatment Outcome; Uridine	2021
Cedazuridine/decitabine: from preclinical to clinical development in myeloid malignancies. Blood advances, 2021, 04-27, Volume: 5, Issue:8 Topics: Azacitidine; Decitabine; Humans; Leukemia, Myelomonocytic, Chronic; Myelodysplastic Syndromes; Uridine	2021
Clinical update on hypomethylating agents. International journal of hematology, 2019, Volume: 110, Issue:2 Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Clinical Trials as Topic; Decitabine; DNA Methylation; Drug Administration Schedule; Drug Combinations; Gene Expression Regulation, Leukemic; Humans; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Myelodysplastic Syndromes; Uridine	2019

Trials

3 trial(s) available for uridine and Myelodysplastic Syndromes

Article	Year
FDA Approval Summary: Decitabine and Cedazuridine Tablets for Myelodysplastic Syndromes. Clinical cancer research : an official journal of the American Association for Cancer Research, 2022, 08-15, Volume: 28, Issue:16 Topics: Adult; Azacitidine; Decitabine; Humans; Myelodysplastic Syndromes; Tablets; Treatment Outcome; Uridine	2022
Oral cedazuridine/decitabine for MDS and CMML: a phase 2 pharmacokinetic/pharmacodynamic randomized crossover study. Blood, 2020, 08-06, Volume: 136, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Capsules; Cross-Over Studies; Decitabine; Disease Progression; DNA Methylation; DNA-Cytosine Methylases; Drug Combinations; Drug Monitoring; Female; Gastrointestinal Diseases; Hematologic Diseases; Humans; Kaplan-Meier Estimate; Least-Squares Analysis; Leukemia, Myeloid, Acute; Leukemia, Myelomonocytic, Chronic; Long Interspersed Nucleotide Elements; Male; Middle Aged; Myelodysplastic Syndromes; Neoplasm Proteins; Tablets; Uridine	2020
An oral fixed-dose combination of decitabine and cedazuridine in myelodysplastic syndromes: a multicentre, open-label, dose-escalation, phase 1 study. The Lancet. Haematology, 2019, Volume: 6, Issue:4 Topics: Administration, Oral; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Decitabine; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Male; Middle Aged; Myelodysplastic Syndromes; Safety; Treatment Outcome; Uridine	2019

Other Studies

4 other study(ies) available for uridine and Myelodysplastic Syndromes

Article	Year
Oral hypomethylating agents: beyond convenience in MDS. Hematology. American Society of Hematology. Education Program, 2021, 12-10, Volume: 2021, Issue:1 Topics: Administration, Oral; Aged; Antimetabolites, Antineoplastic; Azacitidine; Decitabine; Female; Humans; Myelodysplastic Syndromes; Quality of Life; Uridine	2021
A splice site-sensing conformational switch in U2AF2 is modulated by U2AF1 and its recurrent myelodysplasia-associated mutation. Nucleic acids research, 2020, 06-04, Volume: 48, Issue:10 Topics: Fluorescence Resonance Energy Transfer; Humans; Mutation; Myelodysplastic Syndromes; Protein Conformation; RNA Splice Sites; RNA Splicing; Splicing Factor U2AF; Uridine	2020
Decitabine and Cedazuridine. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2020, 10-30, Volume: 77, Issue:22 Topics: Administration, Oral; Adult; Antineoplastic Agents; Cytidine Deaminase; Decitabine; DNA Methylation; DNA Modification Methylases; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Drug Interactions; Drug Labeling; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Myelodysplastic Syndromes; Uridine	2020
The path to approval for oral hypomethylating agents in acute myeloid leukemia and myelodysplastic syndromes. Future oncology (London, England), 2021, Volume: 17, Issue:20 Topics: Antimetabolites, Antineoplastic; Azacitidine; Biological Availability; Clinical Trials, Phase III as Topic; Decitabine; DNA Methylation; Drug Approval; Drug Combinations; Humans; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Randomized Controlled Trials as Topic; Remission Induction; Uridine	2021