uridine has been researched along with Hepatitis, Viral, Non-A, Non-B, Parenterally-Transmitted in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 7 (53.85) | 24.3611 |
| 2020's | 3 (23.08) | 2.80 |
| Authors | Studies |
|---|---|
| Bao, H; Furman, PA; McBrayer, TR; Micolochick Steuer, HM; Murakami, E; Obikhod, A; Otto, MJ; Ramesh, M; Schinazi, RF; Stuyver, LJ; Whitaker, T | 1 |
| Amblard, F; Bassit, L; Cox, BD; Kasthuri, M; Mengshetti, S; Ollinger-Russell, O; Patel, D; Schinazi, RF; Verma, K | 1 |
| Burger, DM; Colbers, A; Drenth, JPH; Freriksen, JJM; Greupink, R; Meijerhof, M; Russel, FGM; van Drongelen, J | 1 |
| Ahsman, MJ; Arrington, L; Gao, W; Kesisoglou, F; Miller, R; Post, TM; Rizk, ML; van den Berg, P | 1 |
| Chang, J; Ho, W; Li, E; Li, H; Li, S; Liu, B; Lv, Z; Peng, Y; Wang, Q; Wang, Y; Yu, W | 1 |
| Brainard, DM; Curtis, C; Lasseter, K; Lawitz, E; Ling, KHJ; Marbury, T; Mathias, A; Mogalian, E; Moorehead, L; Murray, B; Osinusi, A; Perry, R | 1 |
| Krol, E; Pastuch-Gawolek, G; Szewczyk, B; Wandzik, I | 1 |
| Astruc, B; Beigelman, L; Berliba, E; Blatt, LM; Chanda, S; Fry, J; Kakuda, TN; Khorlin, N; McClure, MW; Patat, A; Streinu-Cercel, A; Tsertsvadze, T; Vijgen, L; Vuong, J; Westland, C; Zhang, Q | 1 |
| Beigelman, L; Deval, J; Dyatkina, N; Fung, A; Hu, Y; Huang, Y; Jekle, A; Jin, Z; Kang, H; Prhavc, M; Serebryany, V; Shaw, K; Smith, DB; Stoycheva, A; Tam, Y; Tan, H; Wan, J; Wang, G; Williams, C; Wu, X; Zhang, Q | 1 |
| De Jonghe, S; Gao, LJ; Herdewijn, P; Huang, C; Maiti, M; Murray, MG; Ptak, RG | 1 |
| Balzarini, J; Castelain, S; Duverlie, G; Fournier, C; Josse, S; Marco-Contelles, J; Moura, M; Nguyen Van Nhien, A; Postel, D; Soriano, E | 1 |
| Kim, JH; Lee, SW; Ryu, KJ | 1 |
| Hassan, AE; McBrayer, TR; Otto, MJ; Schinazi, RF; Stuyver, LJ; Tharnish, PM; Wang, P; Watanabe, KA | 1 |
2 trial(s) available for uridine and Hepatitis, Viral, Non-A, Non-B, Parenterally-Transmitted
| Article | Year |
|---|---|
Pharmacokinetics and Safety of Velpatasvir and Sofosbuvir/Velpatasvir in Subjects with Hepatic Impairment.
Topics: Adolescent; Adult; Aged; Antiviral Agents; Carbamates; Drug Combinations; Drug Therapy, Combination; Female; Hepatic Insufficiency; Hepatitis C; Heterocyclic Compounds, 4 or More Rings; Humans; Liver Cirrhosis; Male; Middle Aged; Ribavirin; Sofosbuvir; Uridine; Young Adult | 2018 |
Safety, tolerability, and pharmacokinetics of AL-335 in healthy volunteers and hepatitis C virus-infected subjects.
Topics: Adult; Alanine; Antiviral Agents; Dose-Response Relationship, Drug; Double-Blind Method; Female; Genotype; Half-Life; Hepacivirus; Hepatitis C; Humans; Liver Cirrhosis; Male; Middle Aged; Phosphoramides; Placebo Effect; RNA, Viral; Uridine | 2018 |
11 other study(ies) available for uridine and Hepatitis, Viral, Non-A, Non-B, Parenterally-Transmitted
| Article | Year |
|---|---|
Mechanism of activation of beta-D-2'-deoxy-2'-fluoro-2'-c-methylcytidine and inhibition of hepatitis C virus NS5B RNA polymerase.
Topics: Antiviral Agents; Catalysis; Deoxycytidine; Hepacivirus; Hepatitis C; Humans; Mutation; Phosphorylation; RNA-Dependent RNA Polymerase; RNA, Viral; Structure-Activity Relationship; Viral Nonstructural Proteins; Virus Replication | 2007 |
In silico design of a novel nucleotide antiviral agent by free energy perturbation.
Topics: Antiviral Agents; Hepacivirus; Hepatitis C; Humans; Nucleosides; Nucleotides; Prodrugs; RNA-Dependent RNA Polymerase; Uridine; Viral Nonstructural Proteins; Virus Replication | 2022 |
Transfer of daclatasvir and sofosbuvir's main metabolite, GS-331007, across the human placenta ex vivo.
Topics: Antiviral Agents; Carbamates; Female; Hepatitis C; Humans; Imidazoles; Maternal-Fetal Exchange; Placenta; Pregnancy; Pregnancy Complications, Infectious; Pyrrolidines; Sofosbuvir; Uridine; Valine | 2020 |
Understanding effect site pharmacology of uprifosbuvir, a hepatitis C virus nucleoside inhibitor: Case study of a multidisciplinary modeling approach in drug development.
Topics: Antiviral Agents; Cooperative Behavior; Drug Development; Hepacivirus; Hepatitis C; Humans; Models, Biological; RNA-Dependent RNA Polymerase; Uridine; Viral Load; Viral Nonstructural Proteins | 2021 |
Synthesis and biological evaluation of a novel β-D-2'-deoxy-2'-α-fluoro-2'-β-C-(fluoromethyl)uridine phosphoramidate prodrug for the treatment of hepatitis C virus infection.
Topics: Administration, Oral; Animals; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Hepacivirus; Hepatitis C; Humans; Liver; Mice; Mice, Inbred Strains; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Organophosphorus Compounds; Prodrugs; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Uridine; Virus Replication | 2018 |
Anti-Hepatitis C Virus Activity of Uridine Derivatives of 2-Deoxy Sugars.
Topics: Antiviral Agents; Deoxy Sugars; Hepacivirus; Hepatitis C; Uridine | 2018 |
Synthesis and Anti-HCV Activities of 4'-Fluoro-2'-Substituted Uridine Triphosphates and Nucleotide Prodrugs: Discovery of 4'-Fluoro-2'- C-methyluridine 5'-Phosphoramidate Prodrug (AL-335) for the Treatment of Hepatitis C Infection.
Topics: Alanine; Animals; Antiviral Agents; Cell Line, Tumor; Dogs; Hepacivirus; Hepatitis C; Humans; Nucleic Acid Synthesis Inhibitors; Phosphoramides; Prodrugs; Replicon; Uracil Nucleotides; Uridine; Viral Nonstructural Proteins | 2019 |
Bifunctional aryloxyphosphoramidate prodrugs of 2'-C-Me-uridine: synthesis and anti-HCV activity.
Topics: Amides; Antiviral Agents; Chemistry Techniques, Synthetic; Hepacivirus; Hepatitis C; Humans; Microsomes, Liver; Phosphoric Acids; Prodrugs; Uridine; Virus Replication | 2016 |
Synthesis and in vitro activity of novel N-3 acylated TSAO-T compounds against HIV-1 and HCV.
Topics: Cell Line; Chemistry Techniques, Synthetic; Hepacivirus; Hepatitis C; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Models, Molecular; Reverse Transcriptase Inhibitors; Small Molecule Libraries; Spiro Compounds; Thymidine; Uridine | 2011 |
Ribozyme-mediated selective induction of new gene activity in hepatitis C virus internal ribosome entry site-expressing cells by targeted trans-splicing.
Topics: 5' Untranslated Regions; Animals; Cells, Cultured; Hepacivirus; Hepatitis C; Humans; Luciferases; Mice; Protein Biosynthesis; Ribosomes; RNA Splicing; RNA, Catalytic; RNA, Viral; Trans-Splicing; Transfection; Transgenes; Uridine | 2003 |
Synthesis and anti-hepatitis C virus activity of nucleoside derivatives of N3, 5'-anhydro-4-(beta-D-ribofuranosyl)-8-aza-purin-2-ones.
Topics: Antiviral Agents; Cell Line; Cell-Free System; Chemistry, Pharmaceutical; Drug Design; Hepacivirus; Hepatitis C; Humans; Models, Chemical; Purine Nucleosides; Ribonucleosides; RNA; RNA-Dependent RNA Polymerase; Uridine | 2005 |