uridine has been researched along with Experimental Neoplasms in 257 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 251 (97.67) | 18.7374 |
| 1990's | 3 (1.17) | 18.2507 |
| 2000's | 3 (1.17) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bhagat, M; Chashoo, G; Dutta, S; Mukherjee, A; Sanyal, U; Saxena, AK | 1 |
| SCHMITZ, H | 1 |
| CRUZ, O; GRIESBACH, L; GRUNBERG, E; HEIDELBERGER, C; SCHNITZER, RJ | 1 |
| MORRIS, HP; REID, E | 1 |
| REID, E | 1 |
| BARCLAY, M; JACQUEZ, JA; KRENITSKY, TA | 1 |
| HODAS, S; YOUNG, CW | 1 |
| ROBERTS, E; TANAKA, KK | 1 |
| EASON, R; SMELLIE, RM | 1 |
| Miyamoto, K; Sadzuka, Y; Sawanishi, H; Sugiyama, T; Suzuki, H | 1 |
| Burdon, RH; Lal, BM | 1 |
| Moskalewski, S; Sawicki, W | 1 |
| Együd, LG; Otsuka, H | 2 |
| Fournier, E; Roux, F; Treich, I | 1 |
| Crawford, EJ; Fowler, JS; Friedkin, M; Gallagher, BM; Goldin, A; Lambrecht, RM; MacGregor, RR; Shiue, CY; Wodinsky, I; Wolf, AP | 1 |
| Belt, JA | 1 |
| Fujii, S; Shirasaka, T | 1 |
| Houghton, JA; Houghton, PJ | 1 |
| Knaus, EE; Lee, YW; Mercer, JR; Wiebe, LI | 1 |
| Bogden, AE; Chu, MY; Crabtree, GW; Klein, RS; Lim, MI; Sato, S; Zuckerman, LB | 1 |
| Hadfield, AF; Lazo, JS; Lee, MH; Li, CD; Maniglia, CA; Sartorelli, AC | 1 |
| Lauzon, GJ; Paterson, AR; Yang, S | 1 |
| Leibovici, J; Susskind-Brudner, G; Wolman, M | 1 |
| Lankelma, J; Laurensse, E; Pinedo, HM | 1 |
| Grunbaum, Z; Larson, SM; Rasey, JS | 1 |
| Carlson, G; Mills, GB; Paetkau, V | 1 |
| Lebovitz, HE; McCumbee, WD | 1 |
| Au, JL; Danhauser, L; Luccioni, C; Rustum, YM | 1 |
| Heinstein, P | 1 |
| Glazer, RI; Lloyd, LS | 1 |
| Martin, DS; Sawyer, RC; Spiegelman, S; Stolfi, RL; Young, CW | 1 |
| Fox, JJ; Halat, MJ; Hollenberg, DH; Matsuda, A; Nisselbaum, JS; Watanabe, KA | 1 |
| Belles-Isles, M; Pagé, M | 1 |
| Erlich, S; Miller, CA; Raine, CS | 1 |
| Clement, JJ; Faucette, LF; Howard, WS; Johnson, RK; Wodinsky, I | 1 |
| Bynum, JW | 1 |
| Franko, AJ; Kallman, RF | 1 |
| Benz, C; Cadman, E | 1 |
| Kaku, Y; Kita, J; Koda, A; Maeda, D; Mori, H; Nagai, H; Nakayama, K | 1 |
| Kitaichi, K; Koda, A; Mori, H; Sakamoto, O | 1 |
| Al Safarjalani, ON; Ashour, OM; el Kouni, MH; Naguib, FN; Panzica, RP | 1 |
| Mattern, J; Volm, M; Wayss, K | 1 |
| Bannon, M; Busch, H; Crooke, ST; Sitz, TO | 1 |
| Cihák, A; Rada, B | 1 |
| Grotzinger, K; McGuire, W; Young, R | 1 |
| Abraham, D; Behrens, M; Plagemann, PG | 1 |
| Steinitz, M; Weiss, DW | 1 |
| Faufmann, M; MAttern, J; Volm, M; Wayss, K | 1 |
| Erbe, J; Plagemenn, PG; Richey, DP; Zylka, JM | 1 |
| Arnon, R; Hurwitz, E; Levy, R; Maron, R; Sela, M; Wilchek, M | 1 |
| Furner, RL; Mellett, LB | 1 |
| Hanas, RJ; Tlsty, TD; Wilkinson, DS | 1 |
| de Montalvo, A; Gadaleta, MN; Guerritore, D | 1 |
| Brockman, RW; Nelson, JA; Rose, LM; Schabel, FM; Shaddix, SC; Williams, M | 1 |
| Graff, JC; Plagemann, PG | 1 |
| Chwang, TL; Danenberg, PV; Heidelberger, C; Nesnow, S; Parkhurst, JR; Wood, WF | 1 |
| Behrens, M; Plagemann, PG | 1 |
| Keppler, DO | 1 |
| Blocker, R; Roth, JS | 1 |
| Arbuzov, VA | 1 |
| Barra, R; Hicks, H; Koch, MR; Lea, MA | 1 |
| Marz, R; Plagemann, PG; Wohlhueter, RM | 1 |
| Lupulescu, A | 1 |
| Benvenuto, JA; Loo, TL; Plunkett, W; Stewart, DJ | 1 |
| Grindey, GB; Mihich, E | 1 |
| Maruyama, IN; Suzuki, H; Tanaka, N | 1 |
| Müller, WE; Zahn, RK | 1 |
| Acton, EM; Cheng, CC; Henry, DW; Johnson, RK; Lee, WW; Zee-Cheng, RK | 1 |
| Handschumacher, RE; Moyer, JD | 1 |
| Montgomery, R; Vandré, D | 1 |
| Rothmann, D; Schneider, O; Schussmann, M; Wiskemann, A | 1 |
| Hession, C; Kreis, W; Scully, K; Soricelli, A | 1 |
| Wick, MM | 2 |
| Johnson, RJ; Pasternack, GR; Shin, HS | 1 |
| Brown, J; Collins, JM; Kaplan, AM; Morahan, PS; Snodgrass, MJ | 1 |
| Dickson, JA; Suzangar, M | 1 |
| Izawa, M; Sameshima, M | 1 |
| Johnson, RK | 1 |
| Hinkley, RE; Telser, A | 1 |
| Friedman, SJ; Kimball, T; Skehan, PJ; Trotter, CD | 1 |
| Edmunds, NH; Kwong, LK; Tsuboi, KK | 1 |
| Cha, S; Janeway, CM | 1 |
| Young, RC | 1 |
| Furner, RL; Herren, TC; Mellett, LB | 1 |
| Broome, JD; Jayaram, HN | 1 |
| Diuskaliev, ZhD; Karakulov, RK | 1 |
| Stevens, J; Stevens, YW | 1 |
| Chelibonova-Lorer, H | 1 |
| Carchman, RA; Dewey, WL; Friedman, MA; Harris, LS; Munson, AE | 1 |
| Kaufmann, M; Mattern, J; Volm, M; Wayss, K | 1 |
| Hayatsu, H; Kaneko, I; Satoh, H; Ukita, T | 1 |
| Levy, JG; Whitney, RB | 1 |
| Akao, T; Fujimoto, S; Itoh, B; Koshizuka, I; Koyano, K | 1 |
| Kato, T; Kitaichi, K; Koda, A; Mori, H; Sakamoto, O | 1 |
| Fukukawa, K; Hoshi, A; Iigo, M; Tokuzen, R; Ueda, T; Yoshida, M | 1 |
| Sougawa, M; Tanaka, Y | 1 |
| Boothman, DA; Greer, SB; Mekras, JA | 1 |
| Abe, Y; Ido, T; Ishiwata, K; Matsuzawa, T; Murakami, M | 1 |
| Krepelka, J; Melka, M; Miko, M | 1 |
| Colofiore, JR; Martin, DS; Stolfi, RL | 1 |
| Potapova, GI; Shapot, VS | 1 |
| Henderson, JF; Moyer, JD | 1 |
| Kimmel, CB | 1 |
| Seidel, HJ | 2 |
| Kann, HE; Kohn, KW; Snyder, AL | 1 |
| Cohn, Z; Gordon, S | 1 |
| Balda, BR; Birkmayer, GD; Miller, F | 1 |
| Krueger, RG; Volkman, LE | 1 |
| Goerttler, K; Kaufmann, M; Mattern, J; Volm, M; Wayss, K | 1 |
| Balda, BR; Birkmayer, GD | 1 |
| Pitot, HC; Weiss, JW | 3 |
| Borek, C; Loeb, JN; Yeung, LL | 1 |
| Becker, JE; Bushnell, DE; Potter, VR; Yager, JD | 1 |
| Gerzon, K; Kau, D | 1 |
| Plagemann, PG; Ward, GA | 1 |
| Kemper, B; Rich, A | 1 |
| Hecker, E; Paul, D | 1 |
| Kummer, D | 1 |
| Everson, R; Hall, TC; Kessel, D | 1 |
| Arima, T; Fujii, S; Okuda, H; Shirasaka, T | 1 |
| Plagemann, PG; Swim, HE | 1 |
| Alexander, JA; Hill, DD; Morris, HP; Wheeler, GP | 1 |
| Lamar, C; Munger, WL; Pitot, HC | 1 |
| Hishizawa, T; Matsudaira, H; Nakamura, C; Sekiguchi, T | 1 |
| Cox, RP; Gesner, BM | 1 |
| Plagemann, PG | 6 |
| Hishizawa, T; Matsudaira, H; Nakamura, C | 1 |
| Arendell, JP; Busch, H; Unuma, T | 1 |
| Bader, JP; Nakata, Y | 1 |
| Heidelberger, C; Umeda, M | 1 |
| Izawa, M; Kawashima, K | 2 |
| Korbecki, M; Mahy, BW; Plagemann, PG; Ward, GA | 1 |
| Amalric, F; Simard, R; Zalta, JP | 2 |
| Huppert, J; Semmel, M | 2 |
| Hanafusa, H | 1 |
| Plagemann, PG; Roth, MF | 1 |
| Chen, CC; Kao, WY; Lin, JY; Tserng, KY; Tung, TC | 1 |
| Kowal, J | 1 |
| Frederiksen, S; Hellung-Larsen, P; Tonnesen, T | 1 |
| Estensen, RD | 1 |
| Corbascio, AN; Ishii, DN | 1 |
| Busch, H; Choi, YC; Egawa, K | 1 |
| Bachellerie, JP; Martin-Prevel, C; Zalta, JP | 1 |
| Shearer, RW | 1 |
| Aaronson, SA | 1 |
| Jackson, SH | 1 |
| Chopra, HC; Gazdar, AF; Peebles, PT; Phillips, LA; Sarma, PS | 1 |
| Krystal, G; Webb, TE | 1 |
| Garren, LD; Masui, H | 1 |
| Wolberg, WH | 1 |
| Orengo, A; Saunders, GF | 1 |
| Busch, H; Lewis, BC; Prestayko, AW | 1 |
| Mizel, SB; Wilson, L | 1 |
| Miyamoto, M; Terayama, H | 1 |
| Axel, R; Gebert, R; Orenstein, JM; Stadler, UC; Weinstein, IB | 1 |
| Benyesh-Melnick, M; Biswal, N; Trowbridge, ST | 1 |
| Erbe, J; Plagemann, PG | 4 |
| Estensen, RD; Plagemann, PG | 1 |
| Altaner, C; Hlavayova, E | 1 |
| Pitot, HC; Wilkinson, DS | 1 |
| Lim, R; Mitsunobu, K | 1 |
| Hirschberg, E; Lea, MA; Mackauf, I; Miller, S; Morris, HP | 1 |
| Kurata, S; Ono, T; Saito, M; Sugawara, Y; Wakabayashi, K | 1 |
| Keller, R | 1 |
| Norpoth, K; Oberwittler, W; Witting, U; Wüst, GP | 1 |
| Hatch, GG; Kit, S; May, JT; McCormick, KJ; Somers, KD; Stenback, WA; Trentin, JJ | 1 |
| Chia, LL; Morris, HP; Randerath, E; Randerath, K | 2 |
| Dybing, E | 1 |
| Keppler, DO; Smith, DF | 1 |
| Billiau, A; Eyssen, H; Sobis, H; Van den Berghe, H | 1 |
| Hoogenraad, NJ; Lee, DC | 1 |
| Howard, E; Tidwell, T | 1 |
| Kirsten, WH; Panem, S; Schwartz, SA; Stefanski, E | 1 |
| Hollander, VP; Stevens, J; Stevens, YW | 1 |
| Agrawal, KC; Booth, BA; Mooney, PD; Moore, EC; Sartorelli, AC | 1 |
| Dantchev, D; Hill, M; Hillova, J; Mariage, R; Plichon, MP | 1 |
| Bullock, J; Khalil, FL; Lea, MA; Morris, HP | 1 |
| Gibson, DA; Reichlin, S; Vernadakis, A | 1 |
| Morris, HP; Schumm, DE; Webb, TE | 1 |
| Cremisi, C; Sonenshein, GE; Tournier, P | 1 |
| Peterkofsky, B; Tomkins, GM | 1 |
| Eisenbarth, GS; Lebovitz, HE; Wellman, DK | 1 |
| Jolicoeur, P; Labrie, F | 1 |
| Gorjunova, LE; Grechko, VV; Saccharova, NK | 1 |
| Burton, AF; Storr, JM | 1 |
| Gelboin, HV; Kinoshita, N; Wiebel, FJ | 1 |
| Cooke, A; Dray, S; Giacomoni, D; Heller, P; Wang, SR; Yakulis, V | 1 |
| Baldini, L; Giraldi, T; Steppani, G | 1 |
| Verger, C | 1 |
| Cowan, NJ; Milstein, C | 2 |
| Badger, AM; Cooperband, SR; Green, JA | 1 |
| Latner, AL; Longstaff, E; Turner, GA | 1 |
| Baldi, A; Huseby, RA; Kotoh, K; Samuels, LT | 1 |
| Audette, RC; Connors, TA; Mandel, HG; Merai, K; Ross, WC | 1 |
| Behrens, U; Hollander, VP; Stevens, J; Stevens, YW | 1 |
| Cooper, GM; Greer, S | 1 |
| Kiss, J; Kopper, L; Lapis, K | 1 |
| Byfield, JE; Karlsson, U | 1 |
| Wüst, GP | 1 |
| Kampmann, H; Mattern, J; Schuhmacher, J; Volm, M; Wayss, K; Zimmerer, J | 1 |
| Lehmeyer, JE; MacLeod, RM | 1 |
| Fuska, J; Horáková, K; Ivanitskaya, L; Kuhr, I | 1 |
| Adamson, RH; Fabro, S | 1 |
| Levy, HB; Riley, F | 1 |
| Jarman, M; Kuszmann, J; Stock, JA | 1 |
| Godwin, EL; Rees, KR; Varcoe, JS | 1 |
| Banerjee, MR; Yamamoto, RS | 1 |
| Sanders, BG; Teplitz, RL; Wilkie, M | 1 |
| Jackisch, R; Meier-Gerwert, H; Weitzel, G; Zinser, D | 1 |
| Bates, RR; Gelboin, HV; Klein, M | 1 |
| Ambaye, RY; Schwartz, HS; Sodergren, JE | 1 |
| Hershko, A; Mamont, P; Shields, R; Tomkins, GM | 1 |
| Freeman, AE; Gilden, RV; Huebner, RJ; Kelloff, GJ; Lane, WT; Swain, AP | 1 |
| Bornstein, RS; Yarbro, JW | 1 |
| Bender, E; Rahn, I; Schwabe, K; Widmaier, R | 1 |
| McGowan, J; Poynter, RW; Sternberg, SS; Zedeck, MS | 1 |
| Korner, A; Shields, R | 1 |
| Hu, F; Kitano, Y | 1 |
| Heath, CM; Woods, DA | 1 |
| Krueger, RG; McCarthy, BJ | 1 |
| Fingerhut, B; Graff, S; Veenema, RJ | 1 |
| Fedorov, NA; Matveenko, VN; Tikhonova, EF | 1 |
| Bresnick, E; Burleson, SS | 1 |
| Galt, RM; Knock, FE; Oester, YT; Renaud, OV; Sylvester, R | 1 |
| Bose, S; Coutinho, WG; Gothoskar, BP; Nayak, SK; Ranadive, KJ | 1 |
| Fujinaga, K; Green, M | 1 |
| Granoff, A; Kucera, LS | 1 |
| Betz, T; Bhuyan, BK | 1 |
| Gregg, CT | 1 |
| Evans, VJ; Price, FM; Rotherham, J | 1 |
| Hogan, BL; Korner, A | 2 |
| Orengo, A | 1 |
| Bather, R; Buck, BM | 1 |
| Bekesi, E; Bekesi, JG; Winzler, RJ | 1 |
| Cassingena, R; Simard, R | 1 |
| Bennett, LL; Smithers, D; Struck, RF | 1 |
| Bose, S; Gothoskar, BP | 1 |
| Mainwaring, WI; Williams, DC | 1 |
6 review(s) available for uridine and Experimental Neoplasms
| Article | Year |
|---|---|
Determinants of response to antimetabolites and their modulation by normal purine and pyrimidine metabolites.
Topics: Animals; Antimetabolites, Antineoplastic; Cytarabine; DNA, Neoplasm; Fluorodeoxyuridylate; Fluorouracil; Humans; Leukemia L1210; Neoplasms; Neoplasms, Experimental; Thymidine; Thymidylate Synthase; Uridine | 1981 |
Multiple basis of combination chemotherapy.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Daunorubicin; Drug Antagonism; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Humans; Leucovorin; Mercaptopurine; Methotrexate; Neoplasms; Neoplasms, Experimental; Uridine | 1977 |
A predictive in vitro assay for the sensitivity of human solid tumours to hyperthermia (42 degrees C) and its value in patient management.
Topics: Aged; Animals; Breast Neoplasms; Child; Child, Preschool; DNA, Neoplasm; Evaluation Studies as Topic; Female; Glycolysis; Hot Temperature; Humans; Hyperthermia, Induced; In Vitro Techniques; Leucine; Male; Mice; Middle Aged; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Oxygen Consumption; Rats; Thymidine; Transplantation, Heterologous; Uridine | 1976 |
[Methodological approaches to the study of tumor and body tissue metabolism in vitro and in vivo].
Topics: Animals; Catalysis; Enzymes; Glycolysis; Hexokinase; In Vitro Techniques; Isoenzymes; Liver; Liver Neoplasms, Experimental; Methods; Mice; Neoplasms, Experimental; Orotic Acid; Rats; RNA, Neoplasm; Substrate Specificity; Uridine; Uridine Monophosphate; Uridine Triphosphate | 1986 |
Microsomal aryl hydrocarbon hydroxylases: on their role in polycyclic hydrocarbon carcinogenesis and toxicity and the mechanism of enzyme induction.
Topics: Animals; Benz(a)Anthracenes; Benzopyrenes; Binding Sites; Carbon Isotopes; Carcinogens; Centrifugation, Density Gradient; Cricetinae; Cycloheximide; Dactinomycin; Electrophoresis; Embryo, Mammalian; Enzyme Induction; Flavonoids; Hybridization, Genetic; Kinetics; Liver; Mice; Mice, Inbred Strains; Microsomes, Liver; Mixed Function Oxygenases; Neoplasms, Experimental; RNA; Tritium; Uridine | 1972 |
Antitumor activity and other biologic properties of L-asparaginase (NSC-109229)-a review.
Topics: Animals; Asparaginase; Carcinosarcoma; Dogs; Escherichia coli; Guinea Pigs; Humans; Leukemia; Leukemia, Experimental; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Ligases; Lymphoma; Lymphoma, Non-Hodgkin; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Sarcoma; Tritium; Uridine; Valine | 1968 |
251 other study(ies) available for uridine and Experimental Neoplasms
| Article | Year |
|---|---|
Evaluation of fluoren-NU as a novel antitumor agent.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Evaluation; Humans; Hydantoins; Liver; Male; Mice; Neoplasms, Experimental; Nitrosourea Compounds; Thymidine; Uridine | 2009 |
[Isolation of free nucleotides from various tissues. II. Isolation of adenosine-5-monophosphate, adenosinediphosphate, adenosinetriphosphate, guanosine, cytidine and uridine from ascites tumor of the mouse].
Topics: Adenine Nucleotides; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Ascites; Cytidine; Guanosine; Mice; Neoplasms, Experimental; Nucleotides; Pyrimidines; Uridine | 1954 |
Fluorinated pyrimidines. VI. Effects of 5-fluorouridine and 5-fluoro-2'-deoxyuridine on transplanted tumors.
Topics: Animals; Antineoplastic Agents; Deoxyuridine; Neoplasms, Experimental; Pyrimidines; Uridine | 1958 |
Uridine nucleotide and ribonucleic acid metabolism in the morris 5123 hepatoma.
Topics: Animals; Carcinoma, Hepatocellular; Liver Neoplasms; Liver Neoplasms, Experimental; Neoplasms, Experimental; Nucleotides; RNA; Uracil Nucleotides; Uridine | 1963 |
AZO-DYE CARCINOGENESIS: ENZYMES CONCERNED IN URIDINE NUCLEOTIDE METABOLISM.
Topics: Aspartate Aminotransferases; Azo Compounds; Carboxy-Lyases; Carcinogenesis; Carcinogens; Carcinoma, Hepatocellular; Histocytochemistry; Liver; Liver Neoplasms; Neoplasms, Experimental; Nucleotides; Oxidoreductases; Phosphotransferases; Rats; Research; Transferases; Uracil Nucleotides; Uridine | 1964 |
SPECIFICITY OF MOUSE URIDINE PHOSPHORYLASE. CHROMATOGRAPHY, PURIFICATION, AND PROPERTIES.
Topics: Animals; Carcinoma; Carcinoma, Ehrlich Tumor; Chromatography; Deoxyuridine; Electrophoresis; Escherichia coli; Glucosyltransferases; Intestines; Liver; Mice; Neoplasms, Experimental; Nucleosides; Research; Thymidine; Uridine; Uridine Phosphorylase | 1964 |
HYDROXYUREA: INHIBITORY EFFECT ON DNA METABOLISM.
Topics: Antineoplastic Agents; Cytosine Nucleotides; DNA; DNA, Neoplasm; Guanine Nucleotides; HeLa Cells; Humans; Hydroxyurea; Leucine; Neoplasms, Experimental; Nucleosides; Proteins; Research; RNA; Thymidine; Tissue Culture Techniques; Urea; Urethane; Uridine | 1964 |
AUTORADIOGRAPHIC STUDIES OF MOUSE ASCITES TUMORS, C-1498 AND E.L.4, IN SUSCEPTIBLE (C57BL) A RESISTANT (B10.D2) MICE.
Topics: Amino Acids; Animals; Ascites; Autoradiography; Carcinoma, Ehrlich Tumor; DNA; DNA, Neoplasm; Metabolism; Mice; Mice, Inbred C57BL; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Proteins; Research; RNA; RNA, Neoplasm; Transplantation, Homologous; Uridine | 1964 |
THE INTRACELLULAR SITE OF FORMATION OF ENCEPHALOMYOCARDITIS VIRUS RIBONUCLEIC ACID.
Topics: Cytoplasm; Dactinomycin; Encephalomyocarditis virus; Metabolism; Neoplasms; Neoplasms, Experimental; Nucleosides; Pharmacology; Research; RNA; RNA Viruses; RNA, Neoplasm; RNA, Viral; Uracil Nucleotides; Uridine | 1965 |
Increased effects of MPDAX, a novel xanthine derivative, on antitumor activity of doxorubicin.
Topics: Animals; Antineoplastic Agents; Biological Transport; Cell Line, Tumor; Doxorubicin; Drug Synergism; Male; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Thymidine; Tissue Distribution; Uridine; Xanthines | 2004 |
Maturation of low molecular weight RNA in tumour cells.
Topics: Carbon Isotopes; Chromatography, Gel; Dactinomycin; Methionine; Molecular Weight; Neoplasms, Experimental; RNA; Tritium; Uridine | 1967 |
Effect of crude trypsin on incorporation of 3H-thymidine and 3H-uridine into the Ehrlich ascites tumour cells.
Topics: Animals; Autoradiography; Carcinoma, Ehrlich Tumor; Culture Techniques; Mice; Neoplasms, Experimental; Thymidine; Tritium; Trypsin; Uridine | 1967 |
Nucleic acid and protein synthesis of maligannt ascites cells in the presence of liver extract and methylglyoxal.
Topics: Aldehydes; Carbon Isotopes; DNA; Leucine; Liver; Neoplasms, Experimental; Proteins; Thymidine; Tissue Extracts; Uridine | 1967 |
Nucleic acid and protein synthesis of malignant ascites cells in the presence of liver extract and methylglyoxal.
Topics: Aldehydes; Carbon Isotopes; DNA; Leucine; Liver; Neoplasms, Experimental; Proteins; Thymidine; Tissue Extracts; Uridine | 1967 |
Different levels of changes induced by the insecticide lindane in cultured C-6 glioma cells.
Topics: Aminoisobutyric Acids; Animals; Carrier Proteins; Cells, Cultured; Glioma; Hexachlorocyclohexane; Neoplasms, Experimental; Rats; Uridine | 1980 |
18F-5-Fluorouridine, a new probe for measuring the proliferation of tissue in vivo.
Topics: Animals; Cell Division; Dactinomycin; Female; Fluorine; Isotope Labeling; Mice; Neoplasms, Experimental; Phenylhydrazines; Radioisotopes; RNA; Uridine | 1982 |
Heterogeneity of nucleoside transport in mammalian cells. Two types of transport activity in L1210 and other cultured neoplastic cells.
Topics: 4-Chloromercuribenzenesulfonate; Animals; Biological Transport; Cell Line; Diffusion; Dipyridamole; Leukemia L1210; Mice; Neoplasms, Experimental; Nucleosides; Rats; Thioinosine; Uridine | 1983 |
[Regulation of enzyme activities involved in pyrimidine synthesis and its application to cancer chemotherapy].
Topics: Administration, Oral; Animals; Deoxyuridine; Dihydrouracil Dehydrogenase (NAD+); DNA, Neoplasm; Drug Synergism; Fluorouracil; Neoplasms, Experimental; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Pentosyltransferases; Phosphorylation; Pyrimidines; Sarcoma, Yoshida; Tegafur; Thymidine; Thymine; Uracil; Uridine | 1984 |
On the mechanism of cytotoxicity of fluorinated pyrimidines in four human colon adenocarcinoma xenografts maintained in immune-deprived mice.
Topics: Adenocarcinoma; Animals; Cell Survival; Colonic Neoplasms; Female; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Humans; Male; Mice; Mice, Inbred CBA; Neoplasm Transplantation; Neoplasms, Experimental; Transplantation, Heterologous; Uridine | 1980 |
Tumor uptake of radiolabelled pyrimidine bases and pyrimidine nucleosides in animal models: VI. 1-(3'-[36Cl]-chloro-, 1-(3'-[82Br]-bromo- and 1-(3'-[123I]-Iodo-3'-deoxy-beta-D-arabinofuranosyl)uracil.
Topics: Animals; Arabinofuranosyluracil; Bromine; Chlorine; Female; Iodine Radioisotopes; Male; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Radioisotopes; Radionuclide Imaging; Rats; Rats, Inbred Strains; Tissue Distribution; Uridine | 1984 |
9-Deazaadenosine--a new potent antitumor agent.
Topics: Animals; Antineoplastic Agents; Cell Line; DNA, Neoplasm; Female; Humans; Immunosuppression Therapy; Mice; Neoplasms, Experimental; Ribonucleosides; RNA, Neoplasm; Thymidine; Tubercidin; Uridine | 1984 |
Solubilization of murine melanoma xylosyltransferase and galactosyltransferase activities and their inactivation by dialdehyde nucleosides.
Topics: Adenosine; Aldehydes; Animals; Cell Fractionation; Cell Line; Cytidine; Galactosyltransferases; Hydrogen-Ion Concentration; Inosine; Male; Melanoma; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Octoxynol; Pentosyltransferases; Polyethylene Glycols; Potassium Chloride; Pyridoxal Phosphate; UDP Xylose-Protein Xylosyltransferase; Uridine | 1982 |
Cell cycle arrest as a basis of enhancement of 1-beta-D-arabinofuranosylcytosine anabolism in human lymphoblastoid RPMI 6410 cells cultured with 3-deazauridine.
Topics: 3-Deazauridine; Cell Cycle; Cell Division; Cells, Cultured; Cytarabine; HeLa Cells; Humans; Kinetics; Lymphoma, Non-Hodgkin; Neoplasms, Experimental; Phosphorylation; Time Factors; Uridine | 1981 |
Direct antitumor effect of high-molecular-weight levan on Lewis lung carcinoma cells in mice.
Topics: Animals; Antineoplastic Agents; Carcinoma; Cell Survival; Cells, Cultured; DNA, Neoplasm; Fructans; Leucine; Lung Neoplasms; Male; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Polysaccharides; Thymidine; Transplantation, Isogeneic; Uridine | 1980 |
A flow-through tissue culture system with fast dynamic response.
Topics: Animals; Antibiotics, Antineoplastic; Cell Line; Cell Membrane Permeability; Culture Techniques; Melanoma; Mice; Models, Biological; Naphthacenes; Neoplasms, Experimental; Uridine | 1982 |
Positron imaging feasibility studies: selective tumor concentration of 3H-thymidine, 3H-uridine, and 14C-2-deoxyglucose.
Topics: Animals; Carbon Radioisotopes; Deoxyglucose; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Thymidine; Tomography, Emission-Computed; Tritium; Uridine | 1980 |
Generation of cytotoxic lymphocytes to syngeneic tumors by using co-stimulator (Interleukin 2): in vivo activity.
Topics: Animals; Cell Survival; Cells, Cultured; Cytotoxicity, Immunologic; Interleukin-2; Leukemia, Experimental; Lymphocytes; Lymphokines; Mice; Mice, Inbred DBA; Neoplasms, Experimental; Spleen; Uridine | 1980 |
Hormone responsiveness of a transplantable rat chondrosarcoma. I. In vitro effects of growth hormone-dependent serum factors and insulin.
Topics: Aminoisobutyric Acids; Animals; Biological Transport; Chondrosarcoma; DNA, Neoplasm; Growth Hormone; Hypophysectomy; Insulin; Male; Neoplasm Proteins; Neoplasms, Experimental; Rats; RNA, Neoplasm; Somatomedins; Uridine; Uridine Triphosphate | 1980 |
Mechanism of action of granaticin: inhibition of ribosomal RNA maturation and cell cycle specificity.
Topics: Antibiotics, Antineoplastic; Carcinoma, Squamous Cell; Cell Cycle; Cell Survival; Cells, Cultured; Humans; Naphthoquinones; Neoplasms, Experimental; RNA, Neoplasm; RNA, Ribosomal; Thymidine; Uridine | 1982 |
Association of cell lethality with incorporation of 5-fluorouracil and 5-fluorouridine into nuclear RNA in human colon carcinoma cells in culture.
Topics: Cell Nucleus; Cell Survival; Cells, Cultured; Colonic Neoplasms; DNA, Neoplasm; Fluorouracil; Humans; Neoplasms, Experimental; RNA, Neoplasm; Uridine | 1982 |
High-dose 5-fluorouracil with delayed uridine "rescue" in mice.
Topics: Animals; Colonic Neoplasms; Fluorouracil; Kinetics; Leukopenia; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Uridine | 1982 |
Nucleosides. 114. 5'-O-Glucuronides of 5-fluorouridine and 5-fluorocytidine. Masked precursors of anticancer nucleosides.
Topics: Antineoplastic Agents; Cells, Cultured; Cytidine; Glucuronates; Neoplasms, Experimental; Uridine | 1981 |
Anti-oncofoetal proteins for targeting cytotoxic drugs.
Topics: Antibodies; Antineoplastic Agents; Carcinoembryonic Antigen; Cells, Cultured; Colonic Neoplasms; Daunorubicin; Humans; Neoplasms, Experimental; Stimulation, Chemical; Uridine | 1981 |
Persistent measles virus infection of a clonal line of neuroblastoma: effect on neural differentiation.
Topics: Acetylcholinesterase; Amino Acids; Animals; Antigens, Viral; Cell Transformation, Viral; Clone Cells; Measles virus; Mice; Neoplasms, Experimental; Neuroblastoma; Neurons; Thymidine; Uridine | 1981 |
Influence of pyrazofurin on the toxicity and antitumor activity of fluorinated pyrimidines in vivo.
Topics: Amides; Animals; Antimetabolites, Antineoplastic; Drug Interactions; Drug Therapy, Combination; Female; Fluorouracil; Hematopoietic Stem Cells; Male; Mice; Neoplasms, Experimental; Pyrazoles; Ribonucleosides; Ribose; Uridine | 1980 |
Characterization of adenosine-induced cytostasis in melanoma cells.
Topics: Adenosine; Adenosine Deaminase Inhibitors; Animals; Cell Count; Cell Division; Cell Line; Guanosine; Homocysteine; Melanoma; Methylation; Mice; Neoplasms, Experimental; Pyrimidines; RNA, Neoplasm; Uridine | 1980 |
Cell loss and influx of labeled host cells in three transplantable mouse tumors using [125I]UdR release.
Topics: Animals; Cell Survival; DNA, Neoplasm; Iodine Radioisotopes; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms, Experimental; Time Factors; Uridine | 1980 |
Uridine and cytidine metabolism following inhibition of de novo pyrimidine synthesis by pyrazofurin.
Topics: Amides; Animals; Carcinoma 256, Walker; Cells, Cultured; Cytidine; Leukemia L1210; Leukemia L5178; Leukemia P388; Mice; Neoplasms, Experimental; Pyrazoles; Pyrimidines; Ribonucleosides; Ribose; Sarcoma 180; Uridine | 1980 |
Novel lowly immunosuppressive antitumor fluorouridine derivative, UK-21: antitumor activity and effect on humoral immune response in mice.
Topics: Analysis of Variance; Animals; Antibody Formation; Antineoplastic Agents; Carcinoma; Female; Glycine; Immunosuppressive Agents; Leukemia, Experimental; Lung Neoplasms; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Uridine | 1994 |
Novel low immunosuppressive derivatives of the antitumor drug fluoropyrimidine, UK-21 and UK-25: effect on delayed type hypersensitivity and tumor immunity.
Topics: Animals; Antineoplastic Agents; Erythrocytes; Female; Fluorouracil; Glycine; Hypersensitivity, Delayed; Immunity; Male; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Sheep; Spleen; Uridine | 1993 |
Modulation of 5-fluorouracil host toxicity by 5-(benzyloxybenzyl)barbituric acid acyclonucleoside, a uridine phosphorylase inhibitor, and 2',3',5'-tri-O-acetyluridine, a prodrug of uridine.
Topics: Acetates; Animals; Antimetabolites, Antineoplastic; Barbiturates; Drug Interactions; Enzyme Inhibitors; Female; Fluorouracil; Humans; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Prodrugs; Tumor Cells, Cultured; Uridine; Uridine Phosphorylase | 2000 |
[Correlation of in vitro testing and therapeutical results in animal transplanted tumors after cytostatic treatment].
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Bleomycin; Carcinoma 256, Walker; Cricetinae; Dactinomycin; Doxorubicin; In Vitro Techniques; Male; Melanoma; Neoplasm Transplantation; Neoplasms, Experimental; Plasmacytoma; Podophyllin; Rats; Thymidine; Triaziquone; Uridine | 1975 |
Biochemical effects of bleomycin A2 on Novikoff hepatoma ascites cells.
Topics: Ascitic Fluid; Bleomycin; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Nucleolus; Cell Nucleus; Centrifugation, Density Gradient; DNA, Neoplasm; Leucine; Liver Neoplasms; Neoplasms, Experimental; Nucleic Acid Denaturation; Nucleic Acid Hybridization; Phosphorus; Phosphorus Radioisotopes; RNA, Neoplasm; RNA, Ribosomal; Thymidine; Transcription, Genetic; Tritium; Uridine | 1975 |
Uridine kinase: properties, biological significance and chemotherapeutic aspects (a review).
Topics: Animals; Azacitidine; Azauridine; Molecular Weight; Neoplasms, Experimental; Phosphotransferases; Pyrimidine Nucleosides; Pyrimidines; Species Specificity; Uridine; Uridine Kinase; Virus Diseases | 1976 |
Alterations in [3H]thymidine incorporation into DNA and [3H]uridine incorporation into RNA induced by 5-azacytidine in vivo.
Topics: Animals; Ascites; Azacitidine; Bone Marrow; DNA; Female; Intestinal Mucosa; Mice; Mice, Inbred Strains; Neoplasms, Experimental; RNA; Thymidine; Time Factors; Uridine | 1978 |
Metabolism and cytotoxicity of 5-azacytidine in cultured Novikoff rat hepatoma and P388 mouse leukemia cells and their enhancement by preincubation with pyrazofurin.
Topics: Amides; Animals; Antibiotics, Antineoplastic; Azacitidine; Carcinoma, Hepatocellular; Cell Division; Cell Survival; Cytidine; DNA, Neoplasm; Drug Synergism; Leukemia, Experimental; Liver Neoplasms; Neoplasm Proteins; Neoplasms, Experimental; Phosphates; Pyrazoles; Ribonucleosides; Ribose; RNA, Neoplasm; Uridine | 1978 |
Studies on the physiological manifestations of cell-mediated cytotoxicity. I. Early metabilic changes in mouse plasmacytoma cells exposed in vitro to sensitized allogeneic splenocytes.
Topics: Animals; Carbon Radioisotopes; Cells, Cultured; Chromium Radioisotopes; Cytotoxicity Tests, Immunologic; DNA; Glycine; Immunity, Cellular; Immunization; Leucine; Lymphocyte Culture Test, Mixed; Lymphocytes; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neoplasms, Experimental; Plasmacytoma; Spleen; Thymidine; Tritium; Uridine | 1975 |
Sensitivity tests of tumors to cytostatic agents. I. Comparative investigations on transplanted tumors in vivo and in vitro.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma 256, Walker; Cell Division; Cricetinae; Dactinomycin; Daunorubicin; Dose-Response Relationship, Drug; Doxorubicin; Fluorouracil; In Vitro Techniques; Melanoma; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Plasmacytoma; Procarbazine; Rats; Rats, Inbred ACI; Sarcoma 180; Thymidine; Triaziquone; Uridine | 1975 |
Cell cycle and growth stage-dependent changes in the transport of nucleosides, hypoxanthine, choline, and deoxyglucose in cultured Novikoff rat hepatoma cells.
Topics: Animals; Biological Transport; Carcinoma, Hepatocellular; Cell Division; Cells, Cultured; Choline; Demecolcine; Deoxyglucose; DNA; Glucose; Hydroxyurea; Hypoxanthines; Kinetics; Liver Neoplasms; Mitosis; Neoplasms, Experimental; Nucleosides; Rats; Receptors, Drug; RNA, Neoplasm; Spectrometry, Fluorescence; Thymidine; Time Factors; Tritium; Uridine | 1975 |
The covalent binding of daunomycin and adriamycin to antibodies, with retention of both drug and antibody activities.
Topics: Animals; Antibodies, Neoplasm; Borohydrides; Cells, Cultured; Cytotoxicity Tests, Immunologic; Daunorubicin; Doxorubicin; Immune Sera; Immunoglobulin G; Leukemia, Experimental; Lymphoma; Mice; Mice, Inbred A; Mice, Inbred BALB C; Neoplasms, Experimental; Oxidation-Reduction; Periodic Acid; Plasmacytoma; Protein Binding; Rabbits; RNA, Neoplasm; Serum Albumin, Bovine; Uridine | 1975 |
Kinase and deaminase activity in a variety of subcutaneous mouse tumors.
Topics: Adenocarcinoma; Aminohydrolases; Animals; Cell Line; Chick Embryo; Cytarabine; Freezing; Glioma; Lung Neoplasms; Mammary Neoplasms, Experimental; Melanoma; Mice; Mice, Inbred AKR; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasms, Experimental; Osteosarcoma; Phosphotransferases; Pyrimidine Nucleotides; Sarcoma 180; Tetrahydrouridine; Uridine | 1975 |
The inhibition of ribosomal RNA synthesis and maturation in Novikoff hepatoma cells by 5-fluorouridine.
Topics: Animals; Carcinoma, Hepatocellular; Cells, Cultured; Floxuridine; Fluorouracil; In Vitro Techniques; Liver Neoplasms; Neoplasms, Experimental; RNA, Neoplasm; RNA, Ribosomal; Time Factors; Uridine | 1975 |
RNA synthesis by isolated Yoshida ascites hepatoma A.H. 130 cell mitochondria.
Topics: Animals; Anti-Bacterial Agents; Carcinoma, Hepatocellular; Enzyme Activation; Kinetics; Liver Neoplasms; Magnesium; Male; Manganese; Mitochondria; Neoplasms, Experimental; Osmolar Concentration; Potassium Chloride; Rats; RNA, Neoplasm; Temperature; Uridine | 1975 |
The mechanism of action of 3-deazauridine in tumor cells sensitive and resistant to arabinosylcytosine.
Topics: 3-Deazauridine; Adenocarcinoma; Animals; Cell Line; Cytarabine; Deoxycytidine; Deoxyribonucleotides; DNA, Neoplasm; Drug Resistance; Leukemia L1210; Liver; Mice; Neoplasms, Experimental; Orotic Acid; Phosphotransferases; Pyrimidine Nucleotides; Ribonucleotide Reductases; Ribonucleotides; RNA, Neoplasm; Uracil Nucleotides; Uridine | 1975 |
Alanosine toxicity in Novikoff rat hepatoma cells due to inhibition of the conversion of inosine monophosphate to adenosine monophosphate.
Topics: Adenine; Adenosine Monophosphate; Adenosine Triphosphate; Alanine; Aspartic Acid; Carcinoma, Hepatocellular; Cell Division; Cell Line; Cells, Cultured; Depression, Chemical; DNA, Neoplasm; Glucose; Hypoxanthines; Inosine Nucleotides; Liver Neoplasms; Mengovirus; Neoplasm Proteins; Neoplasms, Experimental; Nitroso Compounds; Purine Nucleotides; Pyrimidine Nucleotides; RNA, Neoplasm; Succinates; Uracil Nucleotides; Uridine | 1976 |
Synthesis and biological studies of 3-(beta-D-ribofuranosyl)-2,3,-dihydro-6H-1,3-oxazine-2,6-dione, a new pyrimidine nucleoside analog related to uridine.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Escherichia coli; Leukemia L1210; Leukemia, Experimental; Liver Neoplasms; Mice; Neoplasms, Experimental; Oxazines; Rats; Ribonucleosides; Uridine; Vaccinia virus; Virus Replication | 1976 |
Inhibition of de novo pyrimidine nucleotide and DNA synthesis and growth of cultured Novikoff rat hepatoma cells and other cell lines by pyrazofurin (NSC 143095).
Topics: Adenosine; Amides; Anti-Bacterial Agents; Carcinoma, Hepatocellular; Cell Division; Cells, Cultured; Deoxycytidine Monophosphate; Dipyridamole; DNA; DNA, Neoplasm; HeLa Cells; L Cells; Liver Neoplasms; Neoplasms, Experimental; Pyrazoles; Pyrimidine Nucleotides; Ribonucleosides; Ribose; RNA; Thymidine; Uridine | 1976 |
Uridine triphosphate deficiency, growth inhibition, and death in ascites hepatoma cells induced by a combination of pyrimidine biosynthesis inhibition with uridylate trapping.
Topics: Animals; Azauridine; Carcinoma, Hepatocellular; Cell Division; Cells, Cultured; Female; Galactosamine; Liver Neoplasms; Neoplasm Transplantation; Neoplasms, Experimental; Pyrimidine Nucleotides; Rats; Time Factors; Transplantation, Homologous; Uracil Nucleotides; Uridine; Uridine Diphosphate Galactose; Uridine Diphosphate Glucose; Uridine Monophosphate | 1977 |
The reduction of uridine 5'-diphosphate and uridine 5'-triphosphate in some transplantable rat hepatomas.
Topics: Animals; Carcinoma, Hepatocellular; Deoxyribonucleosides; Deoxyribonucleotides; Hydrolysis; Hydroxyurea; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Oxidation-Reduction; Rats; Ribonucleotide Reductases; Uracil; Uracil Nucleotides; Uridine; Uridine Diphosphate Glucose; Uridine Monophosphate | 1977 |
[Characteristics of mRNA metabolism in tumor cells. The hypothesis of the uncoupling of the processes of polyribosome formation and functioning in the tumor cell].
Topics: Animals; Biological Transport; Carcinoma, Hepatocellular; Cell Membrane; Cell Nucleus; Cycloheximide; Cytoplasm; Dactinomycin; Free Radicals; Liver Neoplasms; Neoplasms, Experimental; Phenylalanine; Polyribosomes; Rats; RNA, Messenger; RNA, Neoplasm; Uridine | 1977 |
Stimulatory effect of dimethylsulfoxide on [3H]thymidine incorporation into DNA in Novikoff hepatoma cells.
Topics: Amino Acids; Animals; Carcinoma, Hepatocellular; Dimethyl Sulfoxide; DNA, Neoplasm; Dose-Response Relationship, Drug; Female; Liver Neoplasms; Neoplasm Proteins; Neoplasms, Experimental; Rats; RNA, Neoplasm; Thymidine; Uridine | 1978 |
Uridine transport in Novikoff rat hepatoma cells and other cell lines and its relationship to uridine phosphorylation and phosphorolysis.
Topics: Adenosine Triphosphate; Animals; Carcinoma, Hepatocellular; Cell Line; Chloromercuribenzoates; Liver Neoplasms; Neoplasms, Experimental; Nucleosides; Phosphorylation; Rats; Uracil; Uridine; Uridine Kinase | 1978 |
Enhancement of carcinogenesis by prostaglandins in male albino Swiss mice.
Topics: Animals; Carcinoma, Squamous Cell; Hyperplasia; Leucine; Male; Methylcholanthrene; Mice; Microscopy, Electron; Neoplasms, Experimental; Papilloma; Prostaglandins E, Synthetic; Prostaglandins F, Synthetic; Skin Neoplasms; Thymidine; Uridine | 1978 |
High-pressure liquid chromatographic analysis of 3-deazauridine-5'-triphosphate in human cancer cells.
Topics: 3-Deazauridine; Brain Neoplasms; Chromatography, High Pressure Liquid; Humans; In Vitro Techniques; Leukemia, Lymphoid; Male; Middle Aged; Neoplasms; Neoplasms, Experimental; Nucleotides; Time Factors; Uridine; Uridine Triphosphate | 1979 |
Mechanism of action of neothramycin. I. The effect of macromolecular syntheses.
Topics: Animals; Antibiotics, Antineoplastic; Benzodiazepines; Cell Division; DNA; DNA Replication; Escherichia coli; HeLa Cells; Humans; In Vitro Techniques; Lymphoma, Non-Hodgkin; Neoplasms, Experimental; Thymidine; Uridine | 1978 |
Metabolism of 1-beta-D-arabinofuranosyluracil in mouse L5178Y cells.
Topics: Animals; Arabinofuranosyluracil; Arabinonucleosides; Cell Division; Cells, Cultured; DNA, Neoplasm; Lymphoma; Mice; Neoplasms, Experimental; Nucleic Acid Synthesis Inhibitors; Phosphorylation; Uridine | 1979 |
Experimental antitumor activity of aminoanthraquinones.
Topics: Animals; Anthraquinones; Antineoplastic Agents; DNA; Drug Administration Schedule; Female; Leukemia L1210; Male; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Nucleic Acid Denaturation; Structure-Activity Relationship; Thymidine; Time Factors; Uridine | 1979 |
Selective inhibition of pyrimidine synthesis and depletion of nucleotide pools by N-(phosphonacetyl)-L-aspartate.
Topics: Animals; Aspartic Acid; Cells, Cultured; Female; Leukemia L1210; Lung Neoplasms; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Organophosphorus Compounds; Orotic Acid; Phosphonoacetic Acid; Pyrazoles; Pyrimidine Nucleotides; Pyrimidines; Ribonucleosides; Uridine | 1979 |
Strand scission of DNA in KB cells by macromomycin.
Topics: Antibiotics, Antineoplastic; Cells, Cultured; DNA, Neoplasm; Humans; Neoplasms, Experimental; Peptides; Thymidine; Uridine | 1979 |
[In vitro and in vivo sensitivity of animal and human melanomas to various chemotherapeutical agents].
Topics: Animals; Antineoplastic Agents; Cricetinae; Drug Resistance; Humans; In Vitro Techniques; Melanoma; Mice; Neoplasms, Experimental; Nucleosides; Skin Neoplasms; Thymidine; Uridine | 1978 |
Combinations of tetrahydrouridine and cytosine arabinoside in mouse tumors.
Topics: Adenocarcinoma; Animals; Cytarabine; Cytidine Deaminase; Deamination; Drug Evaluation; Drug Therapy, Combination; Female; Lung Neoplasms; Mice; Neoplasms, Experimental; Phosphotransferases; Sarcoma, Experimental; Tetrahydrouridine; Tritium; Uridine | 1977 |
L-Dopa methyl ester: prolongation of survival of neuroblastoma-bearing mice after treatment.
Topics: Animals; Benserazide; Cell Line; Drug Synergism; Leucine; Levodopa; Male; Mice; Neoplasms, Experimental; Neuroblastoma; Thymidine; Uridine | 1978 |
Tumor cell cytostasis by macrophages and antibody in vitro. II. Isolation and characterization of suppressed cells.
Topics: Antibodies; Cell Separation; Cell Transformation, Neoplastic; Dactinomycin; Glucose; Immunosuppression Therapy; Leucine; Macrophages; Neoplasms, Experimental; Uridine | 1978 |
Dopamine: a novel antitumor agent active against B-16 melanoma in vivo.
Topics: Animals; Antineoplastic Agents; Dopamine; Leucine; Melanoma; Mice; Neoplasms, Experimental; Thymidine; Uridine | 1978 |
Mechanism of macrophage-mediated tumor cell cytotoxicity.
Topics: Animals; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cytotoxicity, Immunologic; DNA; Lung Neoplasms; Macrophages; Male; Metaphase; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Uridine | 1978 |
Properties and synthesis of multiple components in native small ribosomal subunits of mouse ascites tumor cells.
Topics: Animals; Cell Fractionation; Centrifugation, Density Gradient; Dactinomycin; Edetic Acid; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Nucleoproteins; Ribosomes; RNA, Neoplasm; Uridine | 1975 |
Reversal of toxicity and antitumor activity of N-(phosphonacetyl)-L-aspartate by uridine or carbamyl-DL-asparate in vivo.
Topics: Animals; Antineoplastic Agents; Aspartic Acid; Body Weight; Carbamates; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Organophosphorus Compounds; Phosphonoacetic Acid; Uridine | 1977 |
Cultured neuroblastoma cells and halothane: effects on cell growth and macromolecular synthesis.
Topics: Animals; Cell Count; Cell Division; Clone Cells; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Halothane; Leucine; Mice; Mitosis; Neoplasm Proteins; Neoplasms, Experimental; Neuroblastoma; Tritium; Uridine | 1977 |
The inhibition of thymidine kinase in glial tumor cells by an amino sugar, D-glucosamine.
Topics: Amino Acids; Cells, Cultured; Cycloheximide; Dactinomycin; Glioma; Glucosamine; Isoenzymes; Kinetics; Neoplasms, Experimental; Thymidine Kinase; Uridine | 1977 |
Selective inhibition of pyrimidine biosynthesis and effect on proliferative growth of colonic cancer cells.
Topics: Animals; Aspartic Acid; Cell Division; Cells, Cultured; Colonic Neoplasms; DNA, Neoplasm; Humans; Kinetics; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms, Experimental; Organophosphorus Compounds; Phosphonoacetic Acid; Pyrimidines; Transplantation, Isogeneic; Uridine | 1977 |
Effects of 6-azauridine on nucleotides, orotic acid, and orotidine in L5178Y mouse lymphoma cells in vitro.
Topics: Azauridine; Cells, Cultured; Lymphoma; Neoplasms, Experimental; Nucleotides; Orotate Phosphoribosyltransferase; Orotic Acid; Orotidine-5'-Phosphate Decarboxylase; Purine Nucleotides; Pyrimidine Nucleotides; Uridine | 1977 |
Kinetic aids to proper chemotherapeutic scheduling: labeled nucleoside incorporation studies in vivo.
Topics: Animals; Bone Marrow; Cell Survival; Cyclophosphamide; DNA, Neoplasm; Drug Administration Schedule; Fluorouracil; Granulocytes; Intestinal Mucosa; Kinetics; Lomustine; Male; Melanoma; Methotrexate; Mice; Neoplasms, Experimental; Pyrimidine Nucleosides; Thymidine; Uridine | 1976 |
Influence of tetrahydrouridine on the phosphorylation of 1-beta-D-arabinofuranosyl-cytosine (ara-C) by enzymes from solid tumors in vitro.
Topics: Adenocarcinoma; Animals; Bone Neoplasms; Cytarabine; Cytidine Deaminase; Deoxycytidine; Female; In Vitro Techniques; Kinetics; L Cells; Liver; Lung Neoplasms; Male; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Osteosarcoma; Phosphorus; Phosphotransferases; Sarcoma 180; Spleen; Tetrahydrouridine; Uridine | 1975 |
Studies of the mechanism of growth promotion of lymphoma cells by 2-mercaptoethanol in vitro.
Topics: Animals; Autoradiography; Cell Division; Cells, Cultured; Culture Media; Disulfides; Growth Substances; Leucine; Leukemia L1210; Lymphoma; Mercaptoethanol; Mice; Neoplasms, Experimental; Serum Albumin, Bovine; Sulfhydryl Compounds; Thymidine; Uridine | 1975 |
[Effect of the degree of hypothermia on the intensity of DNA, RNA and protein synthesis in a tumor and in normal tissue].
Topics: Animals; Autoradiography; Body Temperature; DNA; DNA, Neoplasm; Hypothermia; Liver; Methionine; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms, Experimental; Protein Biosynthesis; Rats; RNA; RNA, Neoplasm; Time Factors; Tritium; Uridine | 1975 |
Sequential irreversible, actinomycin D-sensitive, and cycloheximide-sensitive steps prior to cortisol inhibition of uridine utilization by P1798 tumor lymphocytes.
Topics: Animals; Cycloheximide; Dactinomycin; Depression, Chemical; Female; Hydrocortisone; Hydroxyurea; Lymphocytes; Mice; Mice, Inbred BALB C; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms, Experimental; Phenylalanine; Protein Biosynthesis; RNA; RNA, Neoplasm; Thymidine; Time Factors; Transcription, Genetic; Uridine | 1975 |
Effect of D-glucosamine and D-galactosamine on the uridine nucleotide concentration in mouse myeloid tumor (Graffi) and myeloma MOPC-21.
Topics: Animals; DNA, Neoplasm; Galactosamine; Glucosamine; Mice; Mice, Inbred BALB C; Multiple Myeloma; Neoplasm Transplantation; Neoplasms, Experimental; Nucleotides; Plasmacytoma; RNA, Neoplasm; Transplantation, Homologous; Uracil Nucleotides; Uridine | 1975 |
Antineoplastic activity of cannabinoids.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Cannabidiol; Cannabis; Dactinomycin; Dose-Response Relationship, Drug; Dronabinol; Friend murine leukemia virus; In Vitro Techniques; Leukemia L1210; Lung Neoplasms; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasms, Experimental; Phytotherapy; Splenomegaly; Thymidine; Uridine | 1975 |
[The effect of cyclophosphamide on tumors in the sensitivity-test (author's transl)].
Topics: Adenocarcinoma; Alkylation; Animals; Breast Neoplasms; Carcinoma 256, Walker; Cell Count; Cell Division; Cell Transformation, Neoplastic; Culture Techniques; Cyclophosphamide; Dose-Response Relationship, Drug; Humans; Lung Neoplasms; Male; Mammary Neoplasms, Experimental; Models, Biological; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Structure-Activity Relationship; Thymidine; Time Factors; Tritium; Uridine | 1975 |
Cellular energy dependent agglutination of rat ascites tumor cells mediated by concanavalin A and Ricinus communis agglutinin.
Topics: Agglutination; Animals; Concanavalin A; Cytochalasin B; Dinitrophenols; DNA, Neoplasm; Energy Metabolism; Lectins; Leucine; Neoplasm Proteins; Neoplasms, Experimental; Plant Lectins; Plants, Toxic; Rats; Ricinus; RNA, Neoplasm; Thymidine; Uridine | 1975 |
Mode of action of immunosuppressive substances in sera of tumor-bearing mice.
Topics: Animals; Cell Line; Concanavalin A; Lipopolysaccharides; Lymphocyte Activation; Lymphocytes; Lymphoma; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Rhabdomyosarcoma; Thymidine; Uridine | 1975 |
Effect of N1-(2'-tetrahydrofuryl)-5-fluorouracil and 5-fluorouracil on nucleic acid and protein biosyntheses in Ehrlich ascites cells.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cells, Cultured; DNA, Neoplasm; Fluorouracil; Furans; Liver; Male; Mice; Neoplasm Proteins; Neoplasms, Experimental; RNA, Neoplasm; Time Factors; Uridine | 1976 |
Antitumor activity of two novel low immunosuppressive fluoropyrimidines UK-21 and UK-25.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Body Weight; Fluorouracil; Glycine; Leukemia L1210; Leukemia P388; Lung Neoplasms; Methylcholanthrene; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Transplantation; Neoplasms, Experimental; Organ Size; Sarcoma 180; Spleen; Tegafur; Thymus Gland; Uridine | 1992 |
Antitumor activity of derivatives of neplanocin A in vivo and in vitro.
Topics: Adenosine; Animals; Antibiotics, Antineoplastic; Cells, Cultured; Female; Leucine; Leukemia L1210; Male; Mice; Neoplasms, Experimental; RNA; Sarcoma 180; Uridine | 1986 |
[The modification of radiation effect by nucleoside related compounds on a murine tumor given with local radiotherapy and on survival following whole body irradiation].
Topics: Animals; Arabinofuranosyluracil; Combined Modality Therapy; Deoxyribonucleosides; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Radiation-Protective Agents; Radiation-Sensitizing Agents; Uridine | 1989 |
Use of 5-trifluoromethyldeoxycytidine and tetrahydrouridine to circumvent catabolism and exploit high levels of cytidine deaminase in tumors to achieve DNA- and target-directed therapies.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cells, Cultured; Cytidine Deaminase; Deoxycytidine; DNA; Female; Floxuridine; Fluorouracil; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasms, Experimental; Nucleoside Deaminases; Tetrahydrouridine; Thymidylate Synthase; Trifluridine; Uridine | 1985 |
Studies on 18F-labeled pyrimidines III. Biochemical investigation of 18F-labeled pyrimidines and comparison with 3H-deoxythymidine in tumor-bearing rats and mice.
Topics: Animals; Floxuridine; Fluorouracil; Iron Radioisotopes; Liver Neoplasms, Experimental; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Neoplasms, Experimental; Pyrimidines; Radionuclide Imaging; Rats; Thymidine; Tissue Distribution; Tritium; Uridine | 1985 |
Inhibition of biosynthetic processes in P388 and Ehrlich ascites cells by cloturin.
Topics: Adenine; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; DNA, Neoplasm; Kinetics; Leukemia P388; Mercaptopurine; Mice; Mustard Compounds; Neoplasm Proteins; Neoplasms, Experimental; RNA, Neoplasm; Thymidine; Tumor Cells, Cultured; Uridine | 1988 |
Failure of high-dose leucovorin to improve therapy with the maximally tolerated dose of 5-fluorouracil: a murine study with clinical relevance?
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorouracil; Leucovorin; Mice; Neoplasms, Experimental; Uridine | 1988 |
Salvage of uridine in the mouse. Effect of uridine phosphorylase pretreatment.
Topics: Animals; Mice; Neoplasms, Experimental; Pentosyltransferases; Tritium; Uracil; Uridine; Uridine Phosphorylase | 1985 |
Immunoglobun, protein and nucleic acid synthesis in cultured myeloma cells.
Topics: Animals; Biological Transport; Cell Line; Culture Techniques; gamma-Globulins; Histocytochemistry; Immunoglobulins; Mice; Multiple Myeloma; Neoplasm Proteins; Neoplasms, Experimental; Ribosomes; RNA, Messenger; RNA, Neoplasm; RNA, Transfer; Thymidine; Time Factors; Tritium; Uridine | 1971 |
[Estimation of tumor sensitivity in vitro. II. Studies with the solid Ehrlich carcinoma of the mouse and the GW 77, a heterotransplanted human carcinoma].
Topics: Animals; Antibiotics, Antineoplastic; Autoradiography; Carcinoma; Carcinoma, Ehrlich Tumor; Colonic Neoplasms; Cricetinae; Culture Media; Cytarabine; Dactinomycin; DNA, Neoplasm; Humans; Hydroxyurea; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Nucleosides; RNA, Neoplasm; Thymidine; Triaziquone; Tritium; Uridine | 1970 |
Inhibition of the processing of ribosomal precursor RNA by intercalating agents.
Topics: Acridines; Alkaloids; Animals; Antibiotics, Antineoplastic; Carbon Isotopes; Centrifugation, Density Gradient; Culture Techniques; Cycloheximide; Dactinomycin; Daunorubicin; Indoles; Lymphoma; Mice; Neoplasms, Experimental; Protein Binding; Protein Biosynthesis; Quaternary Ammonium Compounds; Quinolines; Ribosomes; RNA; RNA, Ribosomal; Sucrose; Uridine; Valine | 1971 |
Macrophage-melanoma cell heterokaryons. 3. The activation of macrophage DNA synthesis. Studies with inhibitors of protein synthesis and with synchronized melanoma cells.
Topics: Animals; Anti-Bacterial Agents; Cell Fusion; Cell Nucleus; Cells, Cultured; Cyclohexanes; Cycloheximide; Dactinomycin; DNA; Histocytochemistry; Leucine; Macrophages; Melanoma; Mice; Mitosis; Neoplasm Proteins; Neoplasms, Experimental; Peritoneum; Protein Biosynthesis; Pyridones; RNA, Neoplasm; Thymidine; Tritium; Uridine | 1971 |
Inhibition of high molecular weight RNA synthesis in a hamster melanoma by ethidium bromide in vivo.
Topics: Animals; Antiviral Agents; Cell Fractionation; Centrifugation, Density Gradient; Cricetinae; DNA Nucleotidyltransferases; Enzyme Activation; Ethidium; Melanoma; Neoplasm Transplantation; Neoplasms, Experimental; Oncogenic Viruses; Phenanthridines; RNA Viruses; RNA-Directed DNA Polymerase; RNA, Neoplasm; RNA, Viral; Skin Neoplasms; Subcellular Fractions; Transplantation, Homologous; Uridine | 1972 |
Characterization of C-type particles produced by a tissue culture-adapted murine myeloma.
Topics: Adenine; Animals; Cells, Cultured; Centrifugation, Density Gradient; Ethyl Ethers; Gammaretrovirus; Mice; Mice, Inbred BALB C; Microscopy, Electron; Multiple Myeloma; Neoplasms, Experimental; Phosphotungstic Acid; Retroviridae; Ribonucleases; RNA-Directed DNA Polymerase; RNA, Viral; Staining and Labeling; Surface-Active Agents; Tritium; Uridine | 1973 |
[Selective tumour chemotherapy using oncobiograms (author's transl)].
Topics: Animals; Antineoplastic Agents; Bleomycin; Cricetinae; Culture Techniques; Cytarabine; Dactinomycin; Daunorubicin; Doxorubicin; Drug Evaluation; Drug Resistance; Fluorouracil; Humans; Methods; Methotrexate; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Procarbazine; Radioisotopes; Rats; Scintillation Counting; Thymidine; Triaziquone; Uridine | 1974 |
Drug effects in melanoma: tumor-specific interactions of proflavine and ethidiumbromide.
Topics: Acridines; Animals; Antineoplastic Agents; Cell Transformation, Neoplastic; Centrifugation, Density Gradient; Coloring Agents; Cricetinae; Depression, Chemical; Diamines; DNA, Neoplasm; Ethidium; Melanoma; Neoplasm Transplantation; Neoplasms, Experimental; Oncogenic Viruses; Reverse Transcriptase Inhibitors; RNA; RNA Viruses; RNA, Neoplasm; Templates, Genetic; Tritium; Uridine | 1973 |
Inhibition of ribosomal ribonucleic acid maturation by 5-azacytidine and 8-azaguanine in Novikoff hepatoma cells.
Topics: Animals; Azacitidine; Azaguanine; Carcinoma, Hepatocellular; Cells, Cultured; Cytidine; Dactinomycin; Electrophoresis, Polyacrylamide Gel; Fluorouracil; Guanosine; Isotope Labeling; Liver; Liver Neoplasms; Neoplasms, Experimental; Rats; RNA, Neoplasm; RNA, Ribosomal; Spectrophotometry, Ultraviolet; Time Factors; Tritium; Uridine | 1974 |
Alteration of ribosomal precursor RNA in Novikoff hepatoma cells by 5-azacytidine. Studies on methylation of 45S and 32S RNA.
Topics: Animals; Azacitidine; Azaguanine; Carbon Radioisotopes; Carcinoma, Hepatocellular; Electrophoresis, Polyacrylamide Gel; Guanosine; Liver Neoplasms; Methionine; Neoplasms, Experimental; Rats; RNA, Neoplasm; RNA, Ribosomal; Transcription, Genetic; Tritium; Uridine | 1974 |
Suppression of DNA synthesis in hepatoma cells exposed to glucocorticoid hormone in vitro.
Topics: Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line; Depression, Chemical; Dexamethasone; DNA, Neoplasm; Hydrocortisone; Kinetics; Liver; Liver Neoplasms; Neoplasms, Experimental; Rats; RNA, Neoplasm; Thymidine; Tritium; Tyrosine Transaminase; Uridine | 1973 |
Inhibition of messenger RNA accumulation but not translation in ultraviolet irradiated hepatoma cells.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Dactinomycin; DNA, Neoplasm; Dose-Response Relationship, Radiation; Enzyme Induction; Hydrocortisone; Insulin; Leucine; Liver Neoplasms; Neoplasm Proteins; Neoplasms, Experimental; Protein Biosynthesis; Radiation Effects; Rats; RNA, Messenger; RNA, Neoplasm; Spectrophotometry, Ultraviolet; Thymidine; Time Factors; Transcription, Genetic; Tritium; Tyrosine Transaminase; Ultraviolet Rays; Uridine | 1974 |
The adamantyl group in medicinal agents. 3. Nucleoside 5'-adamantoates. The adamantoyl function as a protecting group.
Topics: Adenocarcinoma; Aminohydrolases; Animals; Antibody Formation; Chemistry, Organic; Culture Techniques; Leukemia L1210; Mice; Neoplasms, Experimental; Nucleosides; Organic Chemistry Phenomena; Polycyclic Compounds; Thymidine; Uridine; Vaccinia virus | 1967 |
Fluctuations of DNA-dependent RNA polymerase and synthesis of macromolecules during the growth cycle of Novikoff rat hepatoma cells in suspension culture.
Topics: Animals; Carcinoma, Hepatocellular; Centrifugation, Density Gradient; Culture Media; Culture Techniques; DNA; DNA, Neoplasm; L-Lactate Dehydrogenase; Liver Neoplasms; Mitosis; Neoplasms, Experimental; Protein Biosynthesis; Rats; Ribosomes; RNA Nucleotidyltransferases; RNA, Neoplasm; Staining and Labeling; Tritium; Trypan Blue; Uridine | 1969 |
[Testing of cytostatic agents on individual tumors].
Topics: Animals; Antineoplastic Agents; Autoradiography; Dactinomycin; Methods; Neoplasms, Experimental; Nucleosides; Rats; Sarcoma, Experimental; Thymidine; Triaziquone; Tritium; Uridine | 1968 |
Identification of presumptive histone messenger RNA in rapidly labelled polysomal RNA of mouse myelomas.
Topics: Animals; Centrifugation, Density Gradient; Cytarabine; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Female; Histones; Isotope Labeling; Mice; Mice, Inbred BALB C; Multiple Myeloma; Neoplasms, Experimental; Plasmacytoma; Polyribosomes; RNA, Messenger; RNA, Ribosomal; Spectrophotometry, Ultraviolet; Time Factors; Tritium; Uridine | 1973 |
On the biochemical mechanism of tumorigenesis in mouse skin. II. Early effects on the biosynthesis of nucleic acids induced by initiating doses of DMBA and by promoting doses of phorbol-12.13-diester TPA.
Topics: Animals; Autoradiography; Benz(a)Anthracenes; Croton Oil; DNA; Mice; Neoplasms, Experimental; RNA; Skin; Skin Neoplasms; Thymidine; Tritium; Uridine | 1969 |
[Effects of cytostatics and x-rays on nucleic acid metabolism of solid, malignant tumors in vitro].
Topics: Adenine; Animals; Antineoplastic Agents; Carbon Isotopes; Dactinomycin; Depression, Chemical; DNA, Neoplasm; Estriol; Fluorouracil; Formates; Glycine; Hypoxanthines; In Vitro Techniques; Leucine; Mercaptopurine; Methotrexate; Methylprednisolone; Neoplasm Proteins; Neoplasms, Experimental; Nucleosides; Orotic Acid; Radiation Effects; RNA, Neoplasm; Testosterone; Thymidine; Triaziquone; Uracil; Uridine | 1970 |
Enzymatic determinants of responsiveness of the LPC-1 plasma cell neoplasm to fluorouracil and fluorodeoxyuridine.
Topics: Animals; Cell Line; Disease Models, Animal; Floxuridine; Fluorouracil; Intestinal Neoplasms; Mice; Neoplasms, Experimental; Nucleotides; Phosphotransferases; Plasmacytoma; Thymidine Kinase; Transferases; Uridine | 1970 |
Studies on a reciprocal relationship between nucleoside kinases and 5'-nucleotidase.
Topics: Adenosine Triphosphatases; Animals; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Cytidine; Cytosine Nucleotides; Dactinomycin; Deoxyribonucleotides; Depression, Chemical; Kidney; Liver; Liver Regeneration; Male; Microsomes, Liver; Neoplasms, Experimental; Nucleotidases; Phosphotransferases; Rats; Thymidine; Thymine Nucleotides; Uracil Nucleotides; Uridine | 1972 |
Replication of mengovirus. II. General properties of the viral-induced ribonucleic acid polymerase.
Topics: Animals; Carbon Isotopes; Culture Techniques; Dactinomycin; DNA; Encephalomyocarditis virus; Hematoma; Neoplasms, Experimental; Nucleotides; Nucleotidyltransferases; Puromycin; Rats; RNA; Temperature; Uridine | 1966 |
Activities of DNA nucleotidyltransferases and other enzymes in cell-free preparations from hepatomas of different growth rates.
Topics: Adenine Nucleotides; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Clinical Enzyme Tests; Cytosine Nucleotides; DNA, Neoplasm; Guanine Nucleotides; Hypoxanthines; Liver; Liver Neoplasms; Neoplasms, Experimental; Nucleosides; Nucleotides; Nucleotidyltransferases; Phosphotransferases; Rats; Thymidine; Uracil; Uridine | 1966 |
Studies on a 32S component of nuclear RNA.
Topics: Adenine; Animals; Carcinoma, Hepatocellular; Cell Nucleus; Centrifugation, Zonal; Chromatography, Gel; Cytosine; Guanine; Liver; Liver Neoplasms; Neoplasms, Experimental; Phosphorus Isotopes; Rats; Ribosomes; RNA; RNA, Neoplasm; Uridine | 1967 |
Effects of x-irradiation on the synthesis of rapidly labelled RNA in experimental tumour of the rat.
Topics: Animals; Autoradiography; Carcinoma, Hepatocellular; Centrifugation, Density Gradient; DNA, Neoplasm; In Vitro Techniques; Liver Neoplasms; Male; Neoplasms, Experimental; Radiation Effects; Rats; RNA, Neoplasm; Tritium; Uridine | 1967 |
Selective effects of L-fucose on BHK21 hamster fibroblasts and on BHK21 cells transformed by infections with polyoma virus.
Topics: Animals; Carbohydrates; Carbon Isotopes; Cell Movement; Contact Inhibition; Cricetinae; Culture Techniques; Fibroblasts; Fucose; Kidney; Leucine; Mice; Neoplasms, Experimental; Polyomavirus; Uridine | 1968 |
On the mechanism of phenethyl alcohol-induced loss of polyribosomes and their re-formation after reversal in rat hepatoma cells.
Topics: Amino Acids; Animals; Antineoplastic Agents; Carbon Isotopes; Carcinoma, Hepatocellular; Centrifugation, Density Gradient; Culture Techniques; Cycloheximide; Dactinomycin; Ethanol; Liver Neoplasms; Neoplasm Proteins; Neoplasms, Experimental; Rats; Ribosomes; RNA, Messenger; Spectrophotometry; Time Factors; Tritium; Uridine | 1968 |
Some characteristics in the pathway of RNA synthesis in hepatoma cells.
Topics: Animals; Ascites; Autoradiography; Carbon Isotopes; Carcinoma, Hepatocellular; Liver Neoplasms; Male; Neoplasms, Experimental; Nucleotidyltransferases; Orotic Acid; p-Dimethylaminoazobenzene; Phosphotransferases; Rats; RNA, Neoplasm; Sarcoma, Yoshida; Transferases; Tritium; Uridine | 1968 |
High resolution autoradiographic studies of the uptake of 3H-5-uridine into condensed and dispersed chromatin of nuclei and granular and fibrillar components of nucleoli of Novikoff hepatoma ascites cells.
Topics: Animals; Ascites; Autoradiography; Carcinoma, Hepatocellular; Cell Nucleolus; Cell Nucleus; Chromosomes; Culture Techniques; Cytoplasm; Liver Neoplasms; Microscopy, Electron; Neoplasms, Experimental; Rats; Tritium; Uridine | 1968 |
Studies on the fixation and development of cellular transformation by Rous sarcoma virus.
Topics: Animals; Cell Transformation, Neoplastic; Culture Techniques; DNA; Mitosis; Neoplasms, Experimental; Sarcoma, Avian; Thymidine; Tritium; Uridine; Virus Replication | 1968 |
Comparative studies of fluorinated pyrimidines with various cell lines.
Topics: Animals; Carcinoma, Hepatocellular; Culture Techniques; Deoxyuridine; Depression, Chemical; DNA, Neoplasm; Floxuridine; HeLa Cells; Leukemia, Experimental; Liver Neoplasms; Neoplasms, Experimental; Nucleosides; Phosphotransferases; Pyrimidines; RNA, Neoplasm; Thymidine; Thymidine Kinase; Uridine | 1968 |
Some properties of ribonucleoprotein particles in the isolated nucleoli of mouse ascites tumor cells.
Topics: Animals; Avian Sarcoma Viruses; Carbon Isotopes; Cell Nucleolus; Centrifugation, Density Gradient; Centrifugation, Zonal; DNA; Electrophoresis; Mice; Neoplasms, Experimental; Nucleoproteins; Ribonucleases; Ribosomes; RNA; Spectrophotometry; Ultracentrifugation; Uridine | 1969 |
Relationship between uridine kinase activity and rate of incorporation of uridine into acid-soluble pool and into RNA during growth cycle of rat hepatoma cells.
Topics: Animals; Carcinoma, Hepatocellular; Cell-Free System; Chromatography, Paper; Culture Media; Culture Techniques; Cycloheximide; Dactinomycin; Depression, Chemical; Electrophoresis; Liver Neoplasms; Mitosis; Neoplasms, Experimental; Phosphotransferases; Proteins; Puromycin; RNA, Neoplasm; Tritium; Uridine | 1969 |
[Effect of supra-optimal temperature on nucleolar ribonucleoproteins and RNA. 1. Ultrastructural study].
Topics: Animals; Ascites; Autoradiography; Carcinoma, Hepatocellular; Cell Nucleolus; Chromosomes; Culture Techniques; Female; Kinetics; Liver Neoplasms; Methods; Microscopy, Electron; Neoplasms, Experimental; Nucleoproteins; Rats; RNA; Temperature; Tritium; Uridine | 1969 |
[Effect of supra-optimal temperature on nucleolar ribonucleoproteins and RNA. II. Biochemical study].
Topics: Ascites; Carcinoma, Hepatocellular; Cell Nucleolus; Centrifugation, Density Gradient; Female; Liver Neoplasms; Methods; Microscopy, Electron; Neoplasms, Experimental; Nucleoproteins; RNA; Temperature; Tritium; Uridine | 1969 |
[Ribonucleic acids and proteins from cells infected by mouse encephalomyocarditis virus (EMC) in the presence of pyronine].
Topics: Amino Acids; Animals; Carbon Isotopes; Centrifugation, Density Gradient; Dactinomycin; Encephalomyocarditis virus; Mice; Neoplasms, Experimental; Quaternary Ammonium Compounds; RNA, Viral; Time Factors; Tritium; Uridine; Viral Proteins | 1969 |
Rapid transformation of cells by Rous sarcoma virus.
Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Neoplastic; Chick Embryo; Culture Media; Culture Techniques; Leucine; Neoplasms, Experimental; Thymidine; Time; Tritium; Trypsin; Uridine | 1969 |
Permeation as the rate-limiting step in the phosphorylation of uridine and choline and their incorporation into macromolecules by Novikoff hepatoma cells. Competitive inhibition by phenethyl alcohol, persantin, and adenosine.
Topics: Animals; Biological Transport; Carcinoma, Hepatocellular; Cell Line; Cell Membrane Permeability; Cell-Free System; Centrifugation, Density Gradient; Choline; Culture Techniques; Depression, Chemical; Dipyridamole; Ethanol; Hydrogen-Ion Concentration; Kinetics; Liver Neoplasms; Neoplasms, Experimental; Nucleotides; Phosphates; Phosphatidylcholines; Phosphotransferases; Rats; RNA; Tritium; Uracil Nucleotides; Uridine | 1969 |
Encephalomyocarditis virus multiplication in the presence of pyronine.
Topics: Amino Acids; Animals; Ascitic Fluid; Carbon Isotopes; Coloring Agents; Culture Techniques; Dactinomycin; Encephalomyocarditis virus; Genetics, Microbial; Mice; Neoplasms, Experimental; Rats; RNA, Viral; Templates, Genetic; Tritium; Uridine; Viral Proteins; Virus Cultivation; Virus Replication; Xanthines | 1970 |
Effect of crystalline abrin on the biosynthesis of protein, RNA, and DNA in experimental tumors.
Topics: Animals; Antimetabolites; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; DNA, Neoplasm; Hot Temperature; Leucine; Liver Neoplasms; Male; Mice; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms, Experimental; Oxygen Consumption; Plant Proteins; Protein Denaturation; Rats; RNA, Neoplasm; Thymidine; Tritium; Uridine | 1970 |
Adrenal cells in tissue culture. VII. The effect of inhibitors of protein synthesis on steroidogenesis and glycolysis.
Topics: Acetates; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Animals; Carbon Isotopes; Cell-Free System; Cholesterol; Culture Techniques; Cycloheximide; Dactinomycin; Depression, Chemical; Glycolysis; Leucine; Lysine; Mice; Neoplasm Proteins; Neoplasms, Experimental; Pregnenolone; Puromycin; RNA, Neoplasm; Tritium; Uridine | 1970 |
Isolation of two small molecular weight RNA components by MAK column chromatography.
Topics: Albumins; Animals; Carcinoma; Carcinoma, Ehrlich Tumor; Cell Nucleus; Centrifugation, Density Gradient; Chromatography; Cytoplasm; Dactinomycin; Metabolism; Methionine; Mice; Molecular Weight; Neoplasms, Experimental; Nucleosides; Nucleotides; Phenols; Phosphorus Isotopes; Ribosomes; RNA, Neoplasm; RNA, Transfer; Silicon Dioxide; Tritium; Uridine | 1971 |
Cytochalasin B. I. Effect on cytokinesis of Novikoff hepatoma cells.
Topics: Animals; Antineoplastic Agents; Benzocycloheptenes; Carcinoma, Hepatocellular; Cell Division; Choline; Depression, Chemical; Dimethyl Sulfoxide; DNA, Neoplasm; In Vitro Techniques; Leucine; Liver Neoplasms; Mitosporic Fungi; Neoplasm Proteins; Neoplasms, Experimental; Rats; RNA, Neoplasm; Thymidine; Tritium; Uridine | 1971 |
Some metabolic effects of halothane on mammalian tissue culture cells in vitro.
Topics: Acetates; Animals; Autoradiography; Carbon Isotopes; Carcinoma, Hepatocellular; Culture Techniques; DNA, Neoplasm; Fatty Acids; Halothane; Leucine; Liver Neoplasms; Neoplasms, Experimental; Phospholipids; Protein Biosynthesis; Rats; RNA, Neoplasm; Thymidine; Time Factors; Tritium; Uridine | 1971 |
Nucleotide pools of Novikoff rat hepatoma cells growing in suspension culture. I. Kinetics of incorporation of nucleosides into nucleotide pools and pool sizes during growth cycle.
Topics: Animals; Aspartic Acid; Biological Transport; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Chromatography, Paper; Culture Media; Culture Techniques; Diffusion; DNA; Electrophoresis; Hypoxanthines; Kinetics; Liver Neoplasms; Neoplasms, Experimental; Nucleosides; Nucleotides; Orotic Acid; Rats; RNA; Thymidine; Time Factors; Tritium; Uracil; Uridine | 1971 |
Nucleotide pools of Novikoff rat hepatoma cells growing in suspension culture. II. Independent nucleotide pools for nucleic acid synthesis.
Topics: Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Cell Nucleus; Culture Media; Culture Techniques; Cytoplasm; Liver Neoplasms; Neoplasms, Experimental; Nucleosides; Nucleotides; RNA, Neoplasm; Temperature; Time Factors; Tritium; Uridine | 1971 |
Studies on the role of 23 s nucleolar RNA as an intermediate in the synthesis of 18 s ribosomal RNA.
Topics: Amino Acid Sequence; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Cell Nucleolus; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Culture Techniques; Liver Neoplasms; Neoplasms, Experimental; Nucleic Acid Hybridization; Nucleosides; Phosphorus Isotopes; Rats; Ribosomes; RNA, Neoplasm; RNA, Ribosomal; Uridine | 1971 |
[Kinetics of the incorporation of uridine ( 3 H) in subnucleolar fractions of rat ascites hepatoma cells].
Topics: Animals; Carcinoma, Hepatocellular; Cell Nucleolus; Centrifugation, Density Gradient; Female; Heparin; In Vitro Techniques; Kinetics; Leucine; Liver Neoplasms; Neoplasms, Experimental; Nucleoproteins; Rats; Ribosomes; RNA, Neoplasm; Tritium; Uridine | 1971 |
DNA of rat hepatomas: search for gene amplification.
Topics: Acetamides; Animals; Carcinoma, Hepatocellular; DNA; DNA, Neoplasm; Drug Stability; Fluorenes; Genes; Genetic Code; Hot Temperature; Kidney; Kinetics; Liver; Liver Neoplasms; Lung; Male; Neoplasm Transplantation; Neoplasms, Experimental; Nucleic Acid Hybridization; Rats; RNA, Neoplasm; Time Factors; Tritium; Uridine | 1971 |
Isolation of a rat-tropic helper virus from M-MSV-O stocks.
Topics: Animals; Antigens; Cell Line; Cell Transformation, Neoplastic; Centrifugation, Density Gradient; Culture Media; Gammaretrovirus; Helper Viruses; Immune Sera; Kidney; Mice; Neoplasms, Experimental; Neutralization Tests; Rats; Species Specificity; Sucrose; Tritium; Uridine; Virus Replication | 1971 |
The metabolic effects of nonvolatile anesthetics on mammalian hepatoma cells in vitro. II. Inhibition of macromolecular precursor incorporation.
Topics: Amobarbital; Animals; Carcinoma, Hepatocellular; Culture Techniques; DNA, Neoplasm; Leucine; Lidocaine; Liver; Liver Neoplasms; Methohexital; Neoplasm Proteins; Neoplasms, Experimental; Rats; RNA, Neoplasm; Thiopental; Thymidine; Uridine | 1971 |
Nucleoside transport by Novikoff rat hepatoma cells glowing in suspension culture. Specificity and mechanism of transport reactions and relationship to nucleoside incorporation into nucleic acids.
Topics: Adenosine; Biological Transport; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Chloromercuribenzoates; Chromatography, Paper; Chymotrypsin; Cytidine; Dipyridamole; Ethanol; Guanosine; Hot Temperature; Inosine; Kinetics; Liver Neoplasms; Neoplasms, Experimental; Neuraminidase; Nucleic Acids; Nucleosides; Phospholipases; Phosphotransferases; Thymidine; Tritium; Trypsin; Uridine | 1971 |
Effects of 3'deoxyadenosine (cordycepin) and 2'deoxyadenosine on nucleoside transport, macromolecular synthesis, and replication of cultured Novikoff hepatoma cells.
Topics: Adenosine; Adenosine Triphosphate; Amino Acids; Animals; Biological Transport; Carcinoma, Hepatocellular; Cell Division; Cell Line; Centrifugation, Density Gradient; Chromatography, Paper; Culture Techniques; Cytosine Nucleotides; Deoxyadenosines; DNA, Neoplasm; Electrophoresis, Paper; Kinetics; Liver Neoplasms; Metabolism; Neoplasm Proteins; Neoplasms, Experimental; Nucleoside Diphosphate Sugars; Nucleosides; Nucleotides; Rats; RNA, Neoplasm; RNA, Transfer; Thymidine; Tritium; Uracil Nucleotides; Uridine | 1971 |
Nucleotide pools in Novikoff rat hepatoma cells growing in suspension culture. 3. Effects of nucleosides in medium on levels of nucleotides in separate nucleotide pools for nuclear and cytoplasmic RNA synthesis.
Topics: Adenine Nucleotides; Adenosine; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Cell Nucleus; Cells, Cultured; Chromatography; Culture Media; Culture Techniques; Cytidine; Cytoplasm; Cytosine Nucleotides; Electrophoresis; Encephalomyocarditis virus; Guanosine; Inosine; Liver Neoplasms; Neoplasms, Experimental; Nucleosides; Nucleotides; Phosphates; Phosphorus Isotopes; Rats; RNA; RNA, Viral; Time Factors; Tritium; Uridine | 1972 |
Presence of sarcoma genome in a "non-infectious" mammalian virus.
Topics: Animals; Antigens, Neoplasm; Antigens, Viral; Cell Transformation, Neoplastic; Cells, Cultured; Centrifugation, Density Gradient; Cricetinae; Gammaretrovirus; Leukemia Virus, Murine; Microscopy, Electron; Neoplasms, Experimental; RNA, Viral; Sarcoma, Experimental; Tritium; Uridine; Virus Replication | 1971 |
Multiple forms of uridine kinase in normal and neoplastic rat liver.
Topics: Animals; Carcinoma, Hepatocellular; Chromatography; Cytoplasm; Fetus; Hepatectomy; Hot Temperature; Isoenzymes; Liver; Liver Neoplasms; Liver Regeneration; Molecular Weight; Neoplasms, Experimental; Phosphotransferases; Rats; Uridine | 1971 |
Inhibition of replication in functional mouse adrenal tumor cells by adrenocorticotropic hormone mediated by adenosine 3':5'-cyclic monophosphate.
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Antineoplastic Agents; Cortisone; Cyclic AMP; Cyclic GMP; Depression, Chemical; DNA, Neoplasm; Hydrocortisone; In Vitro Techniques; Inosine Nucleotides; Leucine; Mice; Neoplasm Proteins; Neoplasms, Experimental; Prednisone; RNA, Neoplasm; Steroids; Thymidine; Tritium; Uridine | 1971 |
Biochemical approaches to prediction of response in solid tumors.
Topics: Adenocarcinoma; Antineoplastic Agents; Carbon Isotopes; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Cells, Cultured; Colonic Neoplasms; DNA, Neoplasm; Drug Resistance; Formates; Head and Neck Neoplasms; Humans; In Vitro Techniques; Liver Neoplasms; Neoplasm Metastasis; Neoplasms; Neoplasms, Experimental; Prognosis; Thymidine; Thymine; Tritium; Uridine | 1971 |
Regulation of a thermostable pyrimidine ribonucleoside kinase by cytidine triphosphate.
Topics: Ammonium Sulfate; Animals; Bacillus; Calcium Phosphates; Carcinoma, Hepatocellular; Centrifugation, Density Gradient; Chemical Phenomena; Chemical Precipitation; Chemistry, Physical; Chromatography, DEAE-Cellulose; Cytidine; Cytosine Nucleotides; Drug Stability; Electrophoresis, Disc; Female; Gels; Hot Temperature; Kinetics; Liver Neoplasms; Neoplasms, Experimental; Phosphotransferases; Protein Conformation; Rats; Temperature; Uridine | 1972 |
Endoribonuclease activity associated with nucleolar ribonucleoprotein particles from Novikoff hepatoma.
Topics: Animals; Carcinoma, Hepatocellular; Cell Nucleolus; Centrifugation, Density Gradient; Edetic Acid; Electrophoresis; Electrophoresis, Paper; Isotope Labeling; Lithium; Liver Neoplasms; Male; Microscopy, Electron; Neoplasms, Experimental; Nucleoproteins; Phosphates; Phosphorus Isotopes; Rats; Ribonucleases; RNA, Neoplasm; Subcellular Fractions; Temperature; Tritium; Uridine | 1972 |
Inhibition of the transport of several hexoses in mammalian cells by cytochalasin B.
Topics: Aminoisobutyric Acids; Animals; Biological Transport; Calcium; Carbon Isotopes; Carcinoma, Hepatocellular; Cells, Cultured; Chick Embryo; Glucosamine; Glucose; Heart; HeLa Cells; Hexokinase; Hexoses; Humans; Liver Neoplasms; Mice; Mycotoxins; Myocardium; Neoplasms, Experimental; Rats; Thymidine; Tritium; Uridine | 1972 |
Tumor cell sap factor stimulating orotate incorporation into nucleic acids in ascites hepatoma cells.
Topics: Aging; Animals; Animals, Newborn; Carbon Isotopes; Carcinoma, Hepatocellular; Cytoplasm; Diphosphates; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Nucleic Acids; Orotic Acid; Pentosyltransferases; Rats; Ribose; Thymidine; Tritium; Uridine | 1972 |
Type C virus from cell cultures of chemically induced rat hepatomas.
Topics: Animals; Avian Leukosis Virus; Bromodeoxyuridine; Carcinoma, Hepatocellular; Cells, Cultured; Deoxyribonucleotides; Dimethyl Sulfoxide; DNA Nucleotidyltransferases; Fluorenes; Liver Neoplasms; Microscopy, Electron; Neoplasms, Experimental; Oncogenic Viruses; Rats; Retroviridae; RNA Viruses; RNA, Viral; Tritium; Uridine | 1972 |
Replication of the Moloney murine sarcoma-leukemia virus in XC cells.
Topics: Animals; Avian Sarcoma Viruses; Cell Fusion; Cell Line; Centrifugation, Density Gradient; Cytopathogenic Effect, Viral; Fibroblasts; Fluorescent Antibody Technique; Gammaretrovirus; Mice; Moloney murine leukemia virus; Neoplasms, Experimental; Neutralization Tests; Rats; RNA, Viral; Time Factors; Tritium; Uridine; Viral Plaque Assay; Virus Replication | 1973 |
Nucleotide pools of Novikoff rat hepatoma cells growing in suspension culture. IV. Nucleoside transport in cells depleted of nucleotides by treatment with KCN.
Topics: Adenine Nucleotides; Animals; Biological Transport, Active; Carcinoma, Hepatocellular; Cell Line; Culture Media; Culture Techniques; Cyanides; Glucose; Kinetics; Liver Neoplasms; Neoplasms, Experimental; Nucleosides; Nucleotides; Potassium; Rats; Tritium; Uracil Nucleotides; Uridine | 1973 |
Thymidine transport by cultured Novikoff hepatoma cells and uptake by simple diffusion and relationship to incorporation into deoxyribonucleic acid.
Topics: Animals; Biological Transport; Carcinoma, Hepatocellular; Cell Line; Cell-Free System; Chloromercuribenzoates; Chromatography, Paper; Diffusion; Dipyridamole; Dithiothreitol; DNA, Neoplasm; Kinetics; Liver Neoplasms; Neoplasms, Experimental; Rats; Temperature; Thymidine; Thymidine Kinase; Thymine Nucleotides; Tritium; Uridine | 1972 |
Cytochalasin B. VI. Competitive inhibition of nucleoside transport by cultured Novikoff rat hepatoma cells.
Topics: Animals; Biological Transport; Carcinoma, Hepatocellular; Cells, Cultured; Choline; DNA, Neoplasm; Indoles; Liver Neoplasms; Neoplasms, Experimental; Rats; RNA, Neoplasm; Thymidine; Tritium; Uridine; Uridine Diphosphate Sugars | 1972 |
Transformation of rat liver cells with chicken sarcoma virus B77 and murine sarcoma virus.
Topics: Alpharetrovirus; Animals; Avian Sarcoma Viruses; Bromodeoxyuridine; Cell Fusion; Cell Line; Cell Transformation, Neoplastic; Chick Embryo; Culture Media; Culture Techniques; DNA Nucleotidyltransferases; Ducks; Gammaretrovirus; Liver; Mice; Neoplasms, Experimental; Parainfluenza Virus 1, Human; Rats; Thymidine; Tritium; Uridine; Viral Plaque Assay | 1973 |
Transport and metabolism of glucosamine by cultured Novikoff rat hepatoma cells and effects on nucleotide pools.
Topics: Adenine Nucleotides; Adenosine; Animals; Biological Transport; Carbon Dioxide; Carbon Isotopes; Carcinoma, Hepatocellular; Cells, Cultured; Chromatography, Paper; Cycloheximide; Cytochalasin B; Diffusion; Dipyridamole; Glucosamine; Glucose; Lactates; Liver Neoplasms; Neoplasms, Experimental; Puromycin; Rats; Ribonucleotides; Tritium; Uracil Nucleotides; Uridine; Uridine Diphosphate Sugars | 1973 |
Inhibition of ribosomal ribonucleic acid maturation in Novikoff hepatoma cells by 5-fluorouracil and 5-fluorouridine.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Electrophoresis; Fluorine; Fluorouracil; Kinetics; Liver Neoplasms; Methionine; Methylation; Neoplasms, Experimental; Rats; RNA, Ribosomal; Tritium; Uracil; Uridine | 1973 |
Effect of dibutyryl cyclic AMP on nucleic acid and protein synthesis in neuronal and glial tumor cells.
Topics: Animals; Astrocytoma; Butyrates; Cell Count; Cell Differentiation; Cell Division; Cell Line; Clone Cells; Cyclic AMP; DNA, Neoplasm; Mice; Neoplasms, Experimental; Nerve Tissue Proteins; Neuroblastoma; Neuroglia; Neurons; Rats; RNA, Neoplasm; Thymidine; Tritium; Uridine | 1972 |
Action of miracil D and related compounds on DNA and RNA synthesis in regenerating liver and hepatomas.
Topics: Animals; Carcinoma, Hepatocellular; DNA; Hepatectomy; Liver Neoplasms; Liver Regeneration; Lucanthone; Male; Neoplasms, Experimental; Orotic Acid; Rats; RNA; Thymidine; Time Factors; Tritium; Uridine | 1972 |
Inhibitory effect of a streptococcal preparation (OK-432) on the nucleic acid synthesis in tumor cells in vitro.
Topics: Animals; Carcinoma; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; DNA, Neoplasm; HeLa Cells; Hot Temperature; Humans; In Vitro Techniques; Liver Neoplasms; Lymphocytes; Mice; Nasopharyngeal Neoplasms; Neoplasms, Experimental; Rats; RNA, Neoplasm; Sarcoma, Yoshida; Streptococcus; Streptococcus pyogenes; Thymidine; Tritium; Uridine | 1973 |
Cytostatic elimination of syngeneic rat tumor cells in vitro by nonspecifically activated macrophages.
Topics: Animals; Antigens, Neoplasm; Benz(a)Anthracenes; Cell Division; Cytotoxicity Tests, Immunologic; Kinetics; Macrophages; Methylcholanthrene; Neoplasms, Experimental; Polyomavirus; Radiation Effects; Rats; Rats, Inbred Strains; Thymidine; Tritium; Uridine | 1973 |
[In vitro effect of hyperthermia on the incorporation rate of nucleic acid precursors in tumours and normal tissues].
Topics: Adenocarcinoma, Mucinous; Animals; Carcinoma 256, Walker; Chick Embryo; Cricetinae; Embryo, Mammalian; Female; Fever; Humans; Liver; Liver Regeneration; Male; Mice; Neoplasms; Neoplasms, Experimental; Rats; Sarcoma, Experimental; Sigmoid Neoplasms; Spleen; Thymidine; Tritium; Uridine | 1973 |
Biochemical properties of a defective hamster C-type oncornavirus.
Topics: Animals; Cell Line; Centrifugation, Density Gradient; Chemical Precipitation; Cricetinae; Defective Viruses; DNA Nucleotidyltransferases; Electrophoresis, Paper; Gammaretrovirus; Lymphoma; Mice; Neoplasms, Experimental; Phosphorus Radioisotopes; Rats; Retroviridae; RNA, Viral; Sodium Dodecyl Sulfate; Tritium; Uridine | 1973 |
Inhibition of ribosomal RNA maturation in Novikoff hepatoma cells by toyocamycin, tubercidin, and 6-thioguanosine.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Carcinoma, Hepatocellular; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Guanosine; Liver Neoplasms; Mercaptopurine; Methionine; Neoplasms, Experimental; Nitriles; Pyrimidines; Pyrroles; Ribonucleosides; RNA, Neoplasm; RNA, Ribosomal; Tritium; Uridine | 1974 |
Transfer RNA base composition studies in Morris hepatomas and rat liver.
Topics: Animals; Base Sequence; Carcinoma, Hepatocellular; Cytidine; Cytoplasm; Electrophoresis, Polyacrylamide Gel; Guanosine; Liver; Liver Neoplasms; Methylation; Neoplasms, Experimental; Rats; RNA, Neoplasm; RNA, Transfer; Tritium; Uridine | 1974 |
Effect of actinomycin D on uptake and incorporation of thymidine and hypoxanthine into the acid-soluble and acid-insoluble fractions of rat hepatoma cells grown in culture.
Topics: Animals; Carcinoma, Hepatocellular; Cells, Cultured; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Hypoxanthines; Kinetics; Liver Neoplasms; Neoplasms, Experimental; Rats; Stimulation, Chemical; Thymidine; Thymidine Kinase; Time Factors; Tritium; Uridine | 1974 |
Nucleotide contents of ascites hepatoma cells and their changes induced by D-galactosamine.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line; Chromatography, Paper; Cytosine Nucleotides; Galactosamine; Galactose; Glucose; Glucuronates; Guanine Nucleotides; Hexosamines; Liver; Liver Glycogen; Liver Neoplasms; Neoplasms, Experimental; Rats; Ribonucleotides; Uracil Nucleotides; Uridine | 1974 |
Non-infectious intracisternal A-type particles in a sarcoma-positive, leukemia-negative mouse cell line transformed by murine sarcoma virus (MSV).
Topics: Animals; Antibodies, Viral; Antibody Formation; Cell Line; Cell Transformation, Neoplastic; Centrifugation, Density Gradient; Fibroblasts; Friend murine leukemia virus; Gammaretrovirus; Helper Viruses; Inclusion Bodies, Viral; Mice; Mice, Inbred C3H; Microscopy, Electron; Neoplasms, Experimental; Rauscher Virus; Retroviridae; Tritium; Uridine | 1973 |
Effect of uridine on de novo pyrimidine biosynthesis in rat hepatoma cells in culture.
Topics: Amidohydrolases; Animals; Aspartate Carbamoyltransferase; Carbamates; Carbon Dioxide; Carbon Radioisotopes; Carboxy-Lyases; Carcinoma, Hepatocellular; Clone Cells; Cycloheximide; Dactinomycin; DNA, Neoplasm; Glutamine; Kinetics; Liver Neoplasms; Neoplasms, Experimental; Orotic Acid; Pentosyltransferases; Phosphotransferases; Pyrimidine Nucleotides; Rats; Ribonucleotides; RNA, Neoplasm; Uridine | 1974 |
The thiolation, methylation, and formation of pseudouridine and dihydrouridine in tRNA of regenerating rat liver, human phytohemagglutinin stimulated lymphocytes, and Novikoff ascites cells.
Topics: Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cells, Cultured; Cysteine; Electrophoresis, Polyacrylamide Gel; Lectins; Liver; Liver Neoplasms; Liver Regeneration; Lymphocytes; Male; Methionine; Methylation; Neoplasms, Experimental; Nucleosides; Orotic Acid; RNA, Neoplasm; RNA, Transfer; Sulfur Radioisotopes; Transcription, Genetic; Uridine | 1972 |
Endogenous type C particles from rat embryo cells treated with 5-bromodeoxyuridine.
Topics: Animals; Animals, Newborn; Antigens, Viral; Bromodeoxyuridine; Cell Transformation, Neoplastic; Cells, Cultured; Centrifugation, Density Gradient; DNA Nucleotidyltransferases; Embryo, Mammalian; Fluorescent Antibody Technique; Mice; Microscopy, Electron; Neoplasms, Experimental; Rats; Rats, Inbred WF; Retroviridae; Time Factors; Tritium; Uridine | 1974 |
Substrate requirements and kinetic analysis of the cortisol effects on uridine uptake and incorporation by mouse lymphoma P1798 cells in vitro.
Topics: Animals; Cells, Cultured; Depression, Chemical; Female; Glucose; Glutamine; Hydrocortisone; Kinetics; Lymphoma, Non-Hodgkin; Mice; Neoplasms, Experimental; Phosphotransferases; Pyruvates; RNA, Neoplasm; Tritium; Uridine | 1974 |
Inhibition of transport systems in cultured rat hepatoma cells by colcemid and ethanol.
Topics: Animals; Biological Transport, Active; Carcinoma, Hepatocellular; Cell Line; Choline; Colchicine; Deoxyglucose; Depression, Chemical; Ethanol; Hypoxanthines; Liver Neoplasms; Mitosis; Neoplasms, Experimental; Rats; Tritium; Uridine | 1974 |
Potential antitumor agents. 10. Synthesis and biochemical properties of 5-N-alkylamino-,N,N-dialkylamino-, and N-alkylacetamido-1-formylisoquinoline thiosemicarbazones.
Topics: Animals; Antineoplastic Agents; Binding Sites; Carcinoma, Hepatocellular; Depression, Chemical; DNA, Neoplasm; Female; Formaldehyde; In Vitro Techniques; Isoquinolines; Liver Neoplasms; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Protein Binding; Rats; Ribonucleoside Diphosphate Reductase; RNA, Neoplasm; Sarcoma 180; Structure-Activity Relationship; Thiosemicarbazones; Thymidine; Tritium; Uridine | 1974 |
Sarcoma and transformation-defective viruses produced with infectious DNA(s) from Rous sarcoma virus (RSV)-transformed chicken cells.
Topics: Alpharetrovirus; Animals; Avian Sarcoma Viruses; Carbon Radioisotopes; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Centrifugation, Density Gradient; Chick Embryo; Chickens; Defective Viruses; DNA, Neoplasm; DNA, Viral; Fibroblasts; Microscopy, Electron; Neoplasms, Experimental; Rats; Retroviridae; RNA, Viral; Tritium; Uridine; Viral Interference | 1974 |
Incorporation of precursors and inhibitors of nucleic acid synthesis into hepatomas and liver of the rat.
Topics: Amino Acids; Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line; Fluorouracil; Injections, Intraperitoneal; Injections, Subcutaneous; Liver; Liver Neoplasms; Liver Regeneration; Male; Neoplasm Transplantation; Neoplasms, Experimental; Orotic Acid; Phosphates; Rats; RNA, Neoplasm; Schistosomicides; Thioxanthenes; Thymidine; Time Factors; Transplantation, Homologous; Tritium; Uracil; Uridine | 1974 |
(3H)Uridine uptake and incorporation into RNA in the C-6 glial cells following dibutyryl cyclic AMP treatment.
Topics: Animals; Astrocytoma; Brain Neoplasms; Bucladesine; Cell Line; DNA, Neoplasm; Models, Biological; Neoplasms, Experimental; Papaverine; Rats; RNA, Neoplasm; Thymidine; Tritium; Uridine | 1974 |
Early biochemical changes in phytohemagglutinin-stimulated peripheral blood lymphocytes from normal and tumor-bearing rats.
Topics: Adrenal Glands; Animals; Biological Assay; Cell Membrane; Cyclic GMP; Immunity, Cellular; Immunosuppression Therapy; Lectins; Lymphocyte Activation; Lymphocytes; Neoplasms, Experimental; Phospholipids; Phosphorus Radioisotopes; Phosphotransferases; Rats; Thymidine; Uridine | 1974 |
Studies on the mechanism of actinomycin D resistance of an SV40-transformed hamster cell line.
Topics: Amino Acids; Animals; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Dactinomycin; Dextrans; Drug Resistance; Neoplasms, Experimental; Ornithine; Peptides; Permeability; Puromycin; RNA, Neoplasm; Simian virus 40; Time Factors; Transcription, Genetic; Tritium; Uridine | 1974 |
Base analysis of RNA by 3H postlabeling--a study of ribothymidine content and degree of base methylation of 4 S RNA.
Topics: Animals; Bacillus subtilis; Brain Chemistry; Carcinoma, Hepatocellular; Chromatography, Thin Layer; Cytosol; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Fluorescence; Isotope Labeling; Liver; Liver Neoplasms; Methylation; Mitochondria, Liver; Muscles; Neoplasms, Experimental; Organ Specificity; Rats; Ribonucleotides; RNA; RNA, Bacterial; RNA, Transfer; Tritium; Uridine | 1974 |
Effect of inhibitors of nucleic acid synthesis on steroid-mediated induction of tyrosine aminotransferase in hepatoma cell cultures.
Topics: Carbon Isotopes; Culture Techniques; Cycloheximide; Cytarabine; Dactinomycin; Dexamethasone; DNA; Enzyme Induction; Mitomycins; Neoplasms, Experimental; RNA; Thymidine; Tritium; Tyrosine Transaminase; Uridine; Valine | 1967 |
Prostaglandin A1 inhibition of chondrosarcoma growth.
Topics: Animals; Carbon Radioisotopes; Chick Embryo; Chondrosarcoma; DNA, Neoplasm; Leucine; Liver; Mice; Neoplasm Proteins; Neoplasms, Experimental; Organ Culture Techniques; Prostaglandins; Rats; RNA, Neoplasm; Sulfur Radioisotopes; Thymidine; Tritium; Uridine | 1974 |
Control of RNA synthesis by amino acids in Landschutz ascites tumor cells.
Topics: Amino Acids; Animals; Arginine; Cell Fractionation; Cell Nucleus; Centrifugation, Density Gradient; Cytoplasm; Electrophoresis, Paper; Electrophoresis, Polyacrylamide Gel; Glutamine; Isotope Labeling; Mice; Microscopy, Electron; Neoplasms, Experimental; Polyribosomes; Ribosomes; RNA, Neoplasm; RNA, Ribosomal; Time Factors; Tritium; Uridine | 1974 |
Some properties of "light" cytoplasmic ribonucleoprotein of mouse plasmacytoma.
Topics: Animals; Cell Fractionation; Cell Nucleus; Centrifugation, Density Gradient; Cytoplasm; Densitometry; Deoxycholic Acid; Ethidium; Mice; Mitochondria; Neoplasm Proteins; Neoplasms, Experimental; Nucleoproteins; Plasmacytoma; Polyribosomes; RNA, Neoplasm; Subcellular Fractions; Surface-Active Agents; Tritium; Ultracentrifugation; Uridine | 1974 |
The effects of arginine deficiency on lymphoma cells.
Topics: Animals; Arginase; Arginine; Carbon Radioisotopes; Cell Count; Cell Line; Cell Survival; Cells, Cultured; Citrulline; Leucine; Leukemia L1210; Leukemia, Lymphoid; Lymphoma, Non-Hodgkin; Mice; Neoplasms, Experimental; Ornithine; Succinates; Thymidine; Tritium; Uridine | 1974 |
In vitro conversion of normal mouse lymphocytes by plasmacytoma RNA to express idiotypic specificities on their surface characteristic of the plasmacytoma immunoglobulin.
Topics: Animals; Antibody Specificity; Binding Sites, Antibody; Cell Membrane; Centrifugation, Density Gradient; Cycloheximide; Dactinomycin; Deoxyribonucleases; DNA, Bacterial; Escherichia coli; Immune Adherence Reaction; Leucine; Liver; Lymphocytes; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Plasmacytoma; Pronase; Puromycin; Rabbits; Ribonucleases; RNA, Bacterial; RNA, Neoplasm; Spleen; Thymidine; Tritium; Uridine | 1974 |
Effects of diazoacetyl-glycine amide on purine nucleotide and deoxyribonucleic acid synthesis in Ehrlich ascites tumor cells.
Topics: Adenine; Amides; Animals; Azo Compounds; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Chromatography, Paper; DNA, Neoplasm; Formates; Glycine; Leucine; Male; Mice; Neoplasm Proteins; Neoplasms, Experimental; Nucleotides; Purine Nucleotides; Thymidine; Time Factors; Tritium; Uridine | 1972 |
[Isolation of high molecular weight messenger RNA from animal cell polysomes].
Topics: Animals; Ascites; Ascitic Fluid; Cells, Cultured; Centrifugation, Density Gradient; Chickens; Leukemia, Experimental; Mice; Molecular Weight; Neoplasms, Experimental; Polyribosomes; RNA, Messenger; Sucrose; Tritium; Uridine | 1972 |
Automatic monitoring of biochemical parameters in tissue culture. Studies on synchronously growing mouse myeloma cells.
Topics: Animals; Autoanalysis; Carbon Isotopes; Culture Techniques; DNA; Lysine; Mice; Mitosis; Multiple Myeloma; Myeloma Proteins; Neoplasms, Experimental; RNA; Thymidine; Tritium; Uridine | 1972 |
Effect of polyriboinosinic-polyribocytidylic acid on the metabolism and viability of cells in vitro.
Topics: Amnion; Animals; Cell Line; Cells, Cultured; Conjunctiva; DNA; DNA, Neoplasm; HeLa Cells; Humans; L Cells; Leucine; Leukocytes; Lymphocytes; Mice; Mitosis; Neoplasm Proteins; Neoplasms, Experimental; Poly I-C; Protein Biosynthesis; Rifampin; RNA; RNA, Neoplasm; Sarcoma; Thymidine; Tritium; Uridine | 1972 |
Enhanced malignant behaviour of cells treated with crude rat liver histone.
Topics: Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Culture Techniques; Histones; Kidney; Liver; Methods; Neoplasm Transplantation; Neoplasms, Experimental; Rats; Tritium; Uridine | 1973 |
Effects of diethylstilbestrol on hybridizability of mouse testicular RNA.
Topics: Adenosine Triphosphate; Animals; Cytosine Nucleotides; Diethylstilbestrol; DNA; DNA-Directed RNA Polymerases; Guanosine Triphosphate; Liver; Male; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Nucleic Acid Hybridization; RNA; Testicular Neoplasms; Testis; Tritium; Uracil Nucleotides; Uridine | 1973 |
Studies on the mechanism of action of the tumour inhibitory triazenes.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Dealkylation; Leucine; Lymphoma; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Microsomes; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosourea Compounds; Plasmacytoma; Platinum; Thymidine; Time Factors; Transplantation, Homologous; Triazenes; Tritium; Uridine | 1973 |
Role of nucleoside transport in glucocorticoid-induced regression of mouse lymphoma P1798.
Topics: Animals; Carbon Isotopes; Glucose; Glucosephosphates; Hydrocortisone; Kinetics; Lymphocytes; Lymphoma; Mice; Neoplasms, Experimental; Nucleosides; Tritium; Uridine | 1973 |
The effect of inhibition of cytidine deaminase by tetrahydrouridine on the utilization of deoxycytidine and 5-bromodeoxycytidine for deoxyribonucleic acid synthesis.
Topics: Adenocarcinoma; Aminohydrolases; Animals; Bone Marrow; Bromine; Cytidine; Deoxycytidine; Deoxyribonucleosides; Deoxyuridine; DNA; DNA, Neoplasm; Female; Fluorine; Intestine, Small; Lymphoma; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Neoplasms, Experimental; Spleen; Testis; Tritium; Uridine | 1973 |
Effect of 1,6-dibromodulcitol (DBD) on the RNA metabolism of S37 tumour cells.
Topics: Animals; Autoradiography; Cell Nucleolus; Cytoplasm; Injections, Intraperitoneal; Mice; Mice, Inbred C57BL; Microscopy, Electron; Mitolactol; Neoplasms, Experimental; RNA, Neoplasm; Tritium; Uridine | 1973 |
Inhibition of replication and differentiation in malignant mouse neuroblasts.
Topics: Amino Acids; Animals; Cell Differentiation; Cell Division; Cell Line; Cell Survival; Cytarabine; DNA Replication; Methotrexate; Mice; Microscopy, Electron; Neoplasm Proteins; Neoplasms, Experimental; Neuroblastoma; RNA; Thymidine; Tritium; Uridine | 1973 |
[Testing the sensitivity of malignant tumors to cytostatics in vitro and in vivo. Methods and clinical experiences].
Topics: Antineoplastic Agents; Culture Techniques; DNA, Neoplasm; Humans; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; RNA, Neoplasm; Thymidine; Tritium; Uridine | 1973 |
Stability of cytoplasmic ribonucleic acid in a mouse myeloma: estimation of the half-life of the messenger RNA coding for an immunoglobulin light chain.
Topics: Animals; Cell Count; Cell Line; Centrifugation, Density Gradient; Cytoplasm; Genetic Code; Half-Life; Immunoglobulins; Mice; Molecular Weight; Multiple Myeloma; Neoplasms, Experimental; Phosphorus Radioisotopes; Polyribosomes; RNA, Messenger; Tritium; Uracil Nucleotides; Uridine | 1974 |
Incorporation of 131 iododeoxyuridine into the DNA of tumour-bearing rats after partial synchronization as a tool in scintigraphic tumour localization.
Topics: Animals; Cell Division; DNA; DNA, Neoplasm; Hydroxyurea; Iodine Radioisotopes; Male; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Radionuclide Imaging; Rats; Thoracic Neoplasms; Time Factors; Transplantation, Homologous; Uridine | 1974 |
Influence of hormone-secretin pituitary tumors on RNA biosynthesis in rat anterior pituitary.
Topics: Animals; Centrifugation, Density Gradient; Dactinomycin; Estradiol; Growth Hormone; Guanosine; In Vitro Techniques; Neoplasms, Experimental; Pituitary Gland; Pituitary Neoplasms; Prolactin; Rats; RNA, Neoplasm; RNA, Transfer; Time Factors; Tritium; Uridine | 1974 |
Letter: The cytotoxic effects of a new antibiotic vermicule.
Topics: Adenine; Animals; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Carbon Radioisotopes; Carcinoma, Ehrlich Tumor; Cells, Cultured; Chemical Phenomena; Chemistry; Lymphoma; Neoplasms, Experimental; Nucleic Acids; Sarcoma, Experimental; Thymidine; Uridine; Valine | 1974 |
The effect of polyinosinic:polycytidylic acid on tumor metabolism.
Topics: Animals; Carbon Isotopes; Cytosine Nucleotides; Depression, Chemical; Lymphoma, Large B-Cell, Diffuse; Mice; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms, Experimental; Nucleosides; Polynucleotides; Proline; RNA, Neoplasm; Species Specificity; Stimulation, Chemical; Tritium; Uridine | 1970 |
Aminoacyl nucleosides derived from the tumour inhibitor, 1-aminocyclopentanecarboxylic acid.
Topics: Aluminum; Amino Acids; Animals; Antineoplastic Agents; Benzyl Compounds; Carbon Isotopes; Catalysis; Chemical Phenomena; Chemistry; Chromatography, Paper; Chromatography, Thin Layer; Cyclopentanes; Drug Stability; Electrophoresis; Escherichia coli; Esters; Half-Life; Hydrogen; Hydrolysis; Leucine; Magnetic Resonance Spectroscopy; Mice; Neoplasms, Experimental; Nucleosides; Oxidation-Reduction; Oxides; Plasmacytoma; Protein Biosynthesis; Stereoisomerism; Tritium; Uridine; Valine | 1969 |
Nuclear RNA synthesis in rat liver during the early stages of chemical carcinogenesis.
Topics: Amides; Animals; Cell Nucleus; Culture Techniques; Electrophoresis; Isocitrate Dehydrogenase; Isoenzymes; L-Lactate Dehydrogenase; Liver Neoplasms; Male; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Rats; RNA; RNA, Neoplasm; Tritium; Uridine | 1967 |
Populations of rat liver parenchymal cells with different patterns of ribonucleic acid synthesis during azo-dye carcinogenesis.
Topics: Animals; Autoradiography; Basophils; Cell Nucleolus; Cytoplasm; Hepatectomy; Liver; Male; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Precancerous Conditions; Rats; RNA; RNA, Neoplasm; Sex Chromatin; Tritium; Uridine | 1968 |
The mitogenic activity of a C57BL-10 mouse transplantable lyhoma.
Topics: Animals; Cell Biology; DNA Replication; Erythrocytes; Erythropoiesis; Histocompatibility; Immunodiffusion; Immunoelectrophoresis; Iodine Isotopes; Iron Isotopes; Lymphoma; Mice; Mitosis; Neoplasm Transplantation; Neoplasms, Experimental; Spleen; Splenic Neoplasms; Transplantation, Homologous; Uridine | 1970 |
[Additional classes of tumor inhibiting compounds. V. Cytostatic properties of alkylated alcohols and aldehydes of the chain length C 8 ].
Topics: Alcohol Oxidoreductases; Alcohols; Aldehydes; Alkylation; Animals; Antineoplastic Agents; Carbon Isotopes; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Cell Line; Cell Membrane; Leucine; Mice; Neoplasms, Experimental; Sarcoma, Yoshida; Skin Neoplasms; Thymidine; Tritium; Uridine | 1972 |
Inhibition of mouse skin tumorigenesis by actinomycin D.
Topics: Animals; Benz(a)Anthracenes; Croton Oil; Dactinomycin; In Vitro Techniques; Leucine; Mice; Neoplasms, Experimental; Protein Biosynthesis; Puromycin; Radiometry; Skin Neoplasms; Tritium; Urethane; Uridine | 1965 |
Actinomycin D: drug concentrations and actions in mouse tissues and tumors.
Topics: Animals; Chromatography, Paper; Dactinomycin; Female; Intestine, Small; Liver; Mice; Neoplasms, Experimental; Osteosarcoma; RNA; Salivary Glands; Spleen; Thymus Gland; Time Factors; Tritium; Uridine | 1968 |
"Pleiotypic response".
Topics: Adenoma; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cell Division; Cell Line; Cell Transformation, Neoplastic; Chloramphenicol; Chromatography, Thin Layer; Culture Techniques; Cycloheximide; DNA; Fibroblasts; Glucose; Growth Substances; Guanine Nucleotides; Insulin; Leucine; Metabolism; Mice; Neoplasms, Experimental; Nucleosides; Protein Biosynthesis; RNA; RNA, Ribosomal; Thymidine; Tritium; Uridine | 1971 |
Activation and isolation of hamster-specific C-type RNA viruses from tumors induced by cell cultures transformed by chemical carcinogens.
Topics: Animals; Antigens, Viral; Autoradiography; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Embryo, Mammalian; Fibroblasts; Methylcholanthrene; Neoplasms, Experimental; Nicotiana; Plants, Toxic; RNA Viruses; RNA, Viral; Smoke; Tritium; Uridine | 1971 |
An evaluation of the mechanism of action of pentamidine isethionate.
Topics: Amides; Amino Acids; Animals; Antiprotozoal Agents; Ascitic Fluid; Carbon Isotopes; DNA; In Vitro Techniques; Mice; Neoplasm Proteins; Neoplasms, Experimental; Nucleotides; Phosphates; Phospholipids; Phosphorus Isotopes; Pneumonia, Pneumocystis; RNA; Thymidine; Time Factors; Tritium; Uridine | 1970 |
[Quantitative differences in nucleic acid and protein metabolism between normal and malignant cell cultures of men and mice].
Topics: Animals; Arginine; Carbon Isotopes; Culture Techniques; Cysteine; DNA; Embryo, Mammalian; Fibroblasts; Glycine; Humans; Kidney; Kidney Neoplasms; Leucine; Lysine; Methionine; Mice; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms, Experimental; RNA, Neoplasm; Sarcoma, Experimental; Sulfur Isotopes; Thymidine; Uridine | 1969 |
Biochemical and pathological effects of methylazoxymethanol acetate, a potent carcinogen.
Topics: Animals; Azo Compounds; Carbon Isotopes; Carcinogens; DNA; Intestine, Small; Kidney; Leucine; Liver; Mice; Microscopy, Electron; Neoplasms, Experimental; Nucleosides; Orotic Acid; Phosphorus Isotopes; Protein Biosynthesis; Rats; RNA; Thymidine; Tritium; Uridine | 1970 |
Regulation of mammalian ribosome synthesis by amino acids.
Topics: Amino Acids; Animals; Carbon Isotopes; Centrifugation, Density Gradient; Chemical Precipitation; Culture Media; Culture Techniques; Cytoplasm; Kinetics; Leucine; Magnesium; Metabolism; Methionine; Mice; Neoplasm Proteins; Neoplasms, Experimental; Nucleosides; Ribosomes; RNA, Neoplasm; Stimulation, Chemical; Time Factors; Tritium; Uridine | 1970 |
DNA, RNA, and protein synthesis of pigment cells in culture.
Topics: Animals; Autoradiography; Chromatophores; Culture Techniques; DNA; Leucine; Melanins; Melanoma; Mice; Neoplasms, Experimental; Pigmentation; Protein Biosynthesis; Puromycin; RNA; Skin; Skin Neoplasms; Thymidine; Tritium; Tyrosine; Uridine | 1970 |
Effects of anti-lymphocyte serum on uptake of uridine by lymph nodes during carcinogenesis.
Topics: Animals; Antilymphocyte Serum; Autoradiography; Benz(a)Anthracenes; Cheek; Cricetinae; Drug Synergism; Hydroquinones; Lymph Nodes; Lymphocyte Activation; Microscopy, Electron; Neoplasms, Experimental; RNA; Stimulation, Chemical; Tritium; Uridine | 1970 |
Hybridization studies with nucleic acids from murine plasma cell tumors.
Topics: Animals; Culture Techniques; DNA, Neoplasm; Filtration; Genes; Hot Temperature; Immunoglobulins; Liver; Mice; Multiple Myeloma; Neoplasms, Experimental; Nucleic Acid Denaturation; RNA, Neoplasm; Spleen; Tritium; Uridine | 1970 |
Nucleic acid synthesis in ladder tumors.
Topics: Animals; Autoradiography; Carcinoma, Transitional Cell; DNA, Neoplasm; Female; Humans; Hyperplasia; Mice; Neoplasms, Experimental; Nucleosides; Radiation Effects; Rats; RNA, Neoplasm; Thymidine; Tritium; Uridine; Urinary Bladder; Urinary Bladder Neoplasms | 1970 |
[Utilization of pyrimidine precursors in the tumor and liver of mice with Ehrlich ascites carcinoma].
Topics: Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cytosine; DNA; DNA, Neoplasm; Liver; Male; Melanoma; Mice; Neoplasms, Experimental; Nucleotides; Orotic Acid; Pyrimidines; RNA; RNA, Neoplasm; Sarcoma 180; Sodium; Thymidine; Thymine; Tritium; Uridine | 1970 |
Rates of turnover of deoxythymidine kinase and of its template RNA in Novikoff hepatoma and neonatal liver.
Topics: Animals; Animals, Newborn; Ascitic Fluid; Aspartic Acid; Carbon Isotopes; Cycloheximide; Dactinomycin; Deoxyribonucleosides; Hematoma; Liver; Male; Neoplasms, Experimental; Phosphotransferases; Protein Biosynthesis; Puromycin; Rats; RNA; Templates, Genetic; Thymidine; Time Factors; Uridine | 1970 |
The use of selected sulfhydryl inhibitors in a preferential drug attack on cancer.
Topics: Adenocarcinoma; Adult; Agar; Animals; Antineoplastic Agents; Anus Neoplasms; Breast Neoplasms; Carcinoma, Squamous Cell; DNA; Dogs; Humans; Leucine; Leukocytes; Liver; Mice; Middle Aged; Neoplasms; Neoplasms, Experimental; Parotid Neoplasms; Proteins; Radioisotopes; Rectal Neoplasms; RNA; Sulfhydryl Compounds; Thoracic Neoplasms; Thymidine; Uridine | 1971 |
Ribonucleic acid synthesis in two cell strains with different grades of malignancy.
Topics: Acridines; Animals; Dactinomycin; Fibrosarcoma; In Vitro Techniques; Mice; Neoplasms, Experimental; RNA, Neoplasm; Tritium; Uridine | 1967 |
Mechanism of viral carcinogenesis by DNA mammalian viruses. V. Properties of purified viral-specific RNA from human adenovirus-induced tumor cells.
Topics: Adenoviridae; Culture Techniques; DNA, Viral; Hybridization, Genetic; Neoplasms, Experimental; Nucleic Acid Denaturation; Oncogenic Viruses; Phosphates; Phosphorus Isotopes; RNA; RNA, Messenger; RNA, Neoplasm; RNA, Transfer; RNA, Viral; Templates, Genetic; Tritium; Uridine | 1968 |
Viruses and renal carcinoma of Rana pipiens. VI. Interrelationships of macromolecular synthesis and infectious virus production in frog virus 3-infected BHK 21/13 cells.
Topics: Adenine; Animals; Anura; Carbon Isotopes; Culture Techniques; Cycloheximide; Cytarabine; Dactinomycin; DNA; DNA, Viral; Herpesviridae; Hydroxyurea; Idoxuridine; Inclusion Bodies, Viral; Kidney Neoplasms; Leucine; Neoplasms, Experimental; Oncogenic Viruses; Protein Biosynthesis; RNA; RNA, Viral; Thymidine; Tritium; Uridine; Viral Proteins; Virus Replication | 1968 |
RNA synthesis in the nucleoli of mouse ascites tumor cells in relation to nucleolar components.
Topics: Animals; Bile Acids and Salts; Carbon Isotopes; Cell Nucleolus; Centrifugation, Zonal; Mice; Neoplasms, Experimental; Nucleotides; Phosphorus Isotopes; Ribosomes; RNA; Solubility; Spectrophotometry; Sulfonic Acids; Ultrasonics; Ultraviolet Rays; Uridine | 1968 |
Studies on the mode of action of the copper(II)chelate of 2-keto-3-ethoxybutyraldehyde-bis(thiosemicarbazone).
Topics: Animals; Antineoplastic Agents; Carbon Isotopes; Carcinoma 256, Walker; Chelating Agents; Copper; Culture Techniques; DNA; DNA Replication; DNA, Neoplasm; Neoplasms, Experimental; Nucleosides; Phosphotransferases; Protein Biosynthesis; Rats; RNA; RNA, Neoplasm; Thiosemicarbazones; Thymidine; Thymidine Kinase; Tritium; Uridine; Valine; Zinc | 1968 |
Inhibition of mammalian cell division by glyoxals.
Topics: Aldehydes; Animals; Carbon Isotopes; Culture Techniques; Cysteine; DNA; Leucine; Mice; Mitosis; Neoplasms, Experimental; Protein Biosynthesis; RNA; Thymidine; Tritium; Uridine | 1968 |
Some aspects of the role of folic acid in nucleic acid synthesis in a neoplastic C3H mouse cell strain.
Topics: Animals; Carbon Isotopes; Cell Transformation, Neoplastic; Culture Techniques; DNA, Neoplasm; Folic Acid; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Orotic Acid; RNA, Neoplasm; Thymidine; Uridine | 1968 |
Ribosomal subunits of Landschütz ascites cells during changes in polysome distribution.
Topics: Amino Acids; Animals; Ascitic Fluid; Carbon Isotopes; Centrifugation, Density Gradient; Culture Media; Culture Techniques; Dactinomycin; Female; Liver; Male; Mice; Neoplasms, Experimental; Orotic Acid; Peritoneum; Rats; Ribosomes; Surface-Active Agents; Tritium; Ultracentrifugation; Uridine | 1968 |
The role of ribosomal subunits and 80-S monomers in polysome formation in an ascites tumour cell.
Topics: Animals; Ascitic Fluid; Carbon Isotopes; Centrifugation, Density Gradient; Female; In Vitro Techniques; Kinetics; Male; Mice; Models, Biological; Neoplasms, Experimental; Protein Biosynthesis; Ribosomes; RNA, Neoplasm; Tritium; Uridine | 1968 |
Regulation of enzymic activity by metabolites. I. Uridine-cytidine kinase of Novikoff ascites rat tumor.
Topics: Adenosine Triphosphate; Animals; Ascitic Fluid; Binding Sites; Carbon Isotopes; Chemical Precipitation; Chromatography, Gel; Cytosine Nucleotides; Drug Stability; Feedback; Female; Guanine Nucleotides; Hydrogen-Ion Concentration; Kinetics; Neoplasms, Experimental; Nucleosides; Phosphotransferases; Rats; Streptomycin; Uracil Nucleotides; Uridine | 1969 |
Requirements for RNA and DNA synthesis in the transformation of mouse embryo cells by murine sarcoma virus (Moloney).
Topics: Cell Line; Cell Transformation, Neoplastic; Culture Techniques; Cytarabine; Dactinomycin; DNA; Embryo, Mammalian; Embryo, Nonmammalian; Mitomycins; Moloney murine leukemia virus; Neoplasms, Experimental; RNA; Thymidine; Tritium; Uridine; Virus Replication | 1969 |
Inhibitory effect of D-glucosamine and other sugars on the biosynthesis of protein, ribonucleic acid, and deoxyribonucleic acid in normal and neoplastic tissues.
Topics: Animals; Carbohydrates; Carbon Isotopes; Carcinoma 256, Walker; DNA; DNA, Neoplasm; Glucosamine; Glucose; Hexosamines; Intestinal Mucosa; Kidney; Liver; Lysine; Male; Mammary Neoplasms, Experimental; Mice; Muscles; Neoplasm Proteins; Neoplasms, Experimental; Protein Biosynthesis; Pyruvates; Rats; RNA; RNA, Neoplasm; Sarcoma 180; Thymidine; Uridine | 1969 |
Actinomycin resistance in cultured hamster cells.
Topics: Animals; Anti-Bacterial Agents; Autoradiography; Cell Division; Cell Line; Cell Membrane Permeability; Cricetinae; Culture Media; Dactinomycin; In Vitro Techniques; Neoplasms, Experimental; Time Factors; Tritium; Uridine | 1969 |
Inhibiton of protein synthesis in mammalian cells by actinobolin.
Topics: Adenocarcinoma; Animals; Anti-Bacterial Agents; Carbon Isotopes; Cell Line; Cell-Free System; Culture Techniques; Cycloheximide; DNA; Humans; Laryngeal Neoplasms; Leucine; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Peptides; Phenylalanine; Protein Biosynthesis; Purines; Puromycin; Ribosomes; RNA; Thymidine; Tritium; Urethane; Uridine | 1969 |
Studies on biological macromolecules. Effect of hydroxylamine on nucleic acid and protein syntheses in mammalian cells in vitro.
Topics: Animals; Autoradiography; Carbon Isotopes; Cell Nucleolus; Cell Nucleus; Culture Techniques; Cytoplasm; DNA; Fibrosarcoma; Humans; Hydroxylamines; Liver; Macromolecular Substances; Mice; Neoplasms, Experimental; Phenylalanine; Protein Biosynthesis; RNA; Thymidine; Tritium; Uridine | 1965 |
The effect of oophorectomy on the ribonucleic acid metabolism of a transplantable uterine tumour.
Topics: Animals; Castration; Chemistry Techniques, Analytical; Dactinomycin; Female; In Vitro Techniques; Neoplasm Proteins; Neoplasm Transplantation; Neoplasms, Experimental; Ovary; Phenylalanine; Puromycin; Rats; RNA, Neoplasm; Uridine; Uterine Neoplasms | 1965 |