uridine has been researched along with Cystic Fibrosis in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (12.50) | 18.7374 |
| 1990's | 1 (4.17) | 18.2507 |
| 2000's | 11 (45.83) | 29.6817 |
| 2010's | 8 (33.33) | 24.3611 |
| 2020's | 1 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Anderson, DG; Bihler, H; Cao, Y; Cheng, Y; Coote, K; Henderson, JM; Jiang, T; Liu, DR; McCaffrey, AP; Mense, M; Newby, GA; Rhym, LH; Valley, HC; Wang, Q; Weng, Z; Xue, W; Zhang, XO | 1 |
| Donaldson, SH; Galietta, L | 1 |
| Storey, S; Wald, G | 1 |
| Thompson, CA | 1 |
| Ratjen, F | 1 |
| Donaldson, SH; Paré, PD; Rosenfeld, M; Tiddens, HA | 1 |
| Davis, SD; Ferkol, TW | 1 |
| Accurso, FJ; Anbar, RD; Durham, TA; Moss, RB; Ramsey, BW; Schaberg, AE; Wilmott, RW | 1 |
| Sly, PD; Stick, SM | 1 |
| Accurso, FJ; Barnes, M; Durham, T; Moss, RB; Navratil, T; Ratjen, F; Schaberg, A; Wainwright, C | 1 |
| Moss, RB | 1 |
| Abraham, WM; Boucher, RC; Boyer, J; Cowlen, M; Davis, CW; Dougherty, R; Jones, AC; Lang-Furr, M; Picher, M; Sabater, JR; Stutts, MJ; Yerxa, BR | 1 |
| Evans, R; Kellerman, D; Mathews, D; Shaffer, C | 1 |
| Daines, C; Deterding, R; Engels, J; Gibson, R; Gorden, J; Lavange, L; Marshall, B; Mathews, D; Milgram, L; Milla, C; Ramsey, B; Retsch-Bogart, G; Schaberg, A; Williams, J; Zeitlin, PL | 1 |
| Brody, AS; Coquillette, SJ; Deterding, RR; Engels, JM; Lavange, LM; Mathews, DW; Millard, SP; Ramsey, BW | 1 |
| Goss, CH; Kerr, D; Mathews, D; McKone, EF; Millard, SP; Wanger, JS | 1 |
| Besier, S; Brade, V; Dehghani, F; Loitsch, S; Saum, SH; Wichelhaus, TA; Zander, J | 1 |
| Engels, J; Gorden, J; Kellerman, D; Rossi Mospan, A; Schaberg, A; Smiley, L | 1 |
| Boucher, RC; Clunes, MT | 1 |
| Limbosch, S; Poliard, A; Van Geffel, R | 1 |
| Abell, CW; Barranco, SC; Bolton, WE; Haenelt, BR | 1 |
| Boucher, RC; Clarke, LL; Knowles, MR | 1 |
| Farrell, PM; Klagsbrun, M | 1 |
5 review(s) available for uridine and Cystic Fibrosis
| Article | Year |
|---|---|
New pulmonary therapies directed at targets other than CFTR.
Topics: Anoctamin-1; Bacteriocins; Chloride Channels; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Deoxycytosine Nucleotides; Diuretics, Osmotic; Epithelial Cells; Epithelial Sodium Channel Blockers; Epithelial Sodium Channels; Humans; Mannitol; Mucociliary Clearance; Neoplasm Proteins; Peptides; Sodium; Uridine | 2013 |
Cystic fibrosis lung disease starts in the small airways: can we treat it more effectively?
Topics: Administration, Inhalation; Airway Obstruction; Airway Remodeling; Anti-Inflammatory Agents; Child; Child, Preschool; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Deoxycytosine Nucleotides; Humans; Infant; Ion Transport; Mannitol; Mucociliary Clearance; Mucus; Neutrophils; Pneumonia, Bacterial; Pulmonary Alveoli; Radiography; Respiratory Mucosa; Sodium Channel Blockers; Uridine; Young Adult | 2010 |
Inhaled P2Y2 receptor agonists as a treatment for patients with Cystic Fibrosis lung disease.
Topics: Administration, Inhalation; Animals; Clinical Trials as Topic; Cystic Fibrosis; Deoxycytosine Nucleotides; Epithelium; Humans; Mucociliary Clearance; Ophthalmic Solutions; Polyphosphates; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2Y2; Uracil Nucleotides; Uridine | 2002 |
Denufosol: a review of studies with inhaled P2Y(2) agonists that led to Phase 3.
Topics: Administration, Inhalation; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cystic Fibrosis; Deoxycytosine Nucleotides; Female; Forced Expiratory Volume; Humans; Male; Polyphosphates; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2Y2; Uracil Nucleotides; Uridine | 2008 |
Front-runners for pharmacotherapeutic correction of the airway ion transport defect in cystic fibrosis.
Topics: Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Deoxycytosine Nucleotides; Humans; Ion Transport; Lung; Mannitol; Peptides, Cyclic; Saline Solution, Hypertonic; Sodium Channel Blockers; Uridine | 2008 |
6 trial(s) available for uridine and Cystic Fibrosis
| Article | Year |
|---|---|
Denufosol tetrasodium in patients with cystic fibrosis and normal to mildly impaired lung function.
Topics: Adolescent; Adult; Analysis of Variance; Child; Child, Preschool; Cystic Fibrosis; Deoxycytosine Nucleotides; Double-Blind Method; Female; Humans; Lung; Male; Respiratory Function Tests; Severity of Illness Index; Treatment Outcome; Uridine; Young Adult | 2011 |
Exciting new clinical trials in cystic fibrosis: infants need not apply.
Topics: Adult; Age Factors; Child, Preschool; Cystic Fibrosis; Deoxycytosine Nucleotides; Humans; Infant; Infant, Newborn; Lung; Uridine | 2011 |
Long term effects of denufosol tetrasodium in patients with cystic fibrosis.
Topics: Administration, Inhalation; Adolescent; Adult; Child; Child, Preschool; Chlorides; Cystic Fibrosis; Deoxycytosine Nucleotides; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Incidence; Kaplan-Meier Estimate; Lung; Lung Diseases; Male; Treatment Outcome; Uridine; Young Adult | 2012 |
Safety and tolerability of denufosol tetrasodium inhalation solution, a novel P2Y2 receptor agonist: results of a phase 1/phase 2 multicenter study in mild to moderate cystic fibrosis.
Topics: Administration, Inhalation; Adolescent; Child; Cystic Fibrosis; Deoxycytosine Nucleotides; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Male; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2Y2; Uridine | 2005 |
Phase 2 randomized safety and efficacy trial of nebulized denufosol tetrasodium in cystic fibrosis.
Topics: Adolescent; Adult; Child; Cough; Cystic Fibrosis; Deoxycytosine Nucleotides; Double-Blind Method; Female; Humans; Lung Volume Measurements; Male; Middle Aged; Nebulizers and Vaporizers; Purinergic P2 Receptor Agonists; Treatment Outcome; Uridine | 2007 |
Experience using centralized spirometry in the phase 2 randomized, placebo-controlled, double-blind trial of denufosol in patients with mild to moderate cystic fibrosis.
Topics: Administration, Inhalation; Adolescent; Cystic Fibrosis; Deoxycytosine Nucleotides; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Maximal Expiratory Flow Rate; Severity of Illness Index; Spirometry; Treatment Outcome; Uridine; Vital Capacity | 2008 |
13 other study(ies) available for uridine and Cystic Fibrosis
| Article | Year |
|---|---|
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Chemical modifications of adenine base editor mRNA and guide RNA expand its application scope.
Topics: Adenine; Alleles; Animals; Cell Line; Codon; Codon, Nonsense; CRISPR-Cas Systems; Cystic Fibrosis; Gene Editing; HEK293 Cells; Humans; Mice; Mutation; Nucleotides; Phenotype; Plasmids; RNA, Guide, Kinetoplastida; RNA, Messenger; Transfection; Uridine | 2020 |
Novel agents in cystic fibrosis.
Topics: Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Deoxycytosine Nucleotides; Genetic Therapy; Humans; Mannitol; Natriuretic Agents; Osmolar Concentration; Uridine | 2008 |
Drug developers aim to treat cystic fibrosis through disease modification.
Topics: Administration, Inhalation; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Deoxycytosine Nucleotides; Genetic Therapy; Humans; Mutation; Oxadiazoles; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2Y2; Uridine | 2008 |
Update in cystic fibrosis 2008.
Topics: Amiloride; Animals; Bacterial Infections; Biomarkers; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Deoxycytosine Nucleotides; Disease Progression; Humans; Inflammation; Lung; Oxadiazoles; Respiratory Function Tests; Sodium Channel Blockers; Uridine | 2009 |
Hitting the target: new treatments for cystic fibrosis.
Topics: Administration, Inhalation; Adolescent; Adult; Child; Child, Preschool; Cystic Fibrosis; Deoxycytosine Nucleotides; Diuretics, Osmotic; Humans; Infant; Mannitol; Treatment Outcome; Uridine; Young Adult | 2010 |
Pitfalls of drug development: lessons learned from trials of denufosol in cystic fibrosis.
Topics: Adolescent; Alleles; Child; Child, Preschool; Clinical Trials as Topic; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Deoxycytosine Nucleotides; Disease Progression; Drug Design; Drug Industry; Female; Humans; Inflammation; Male; Research Design; Sputum; Time Factors; Treatment Outcome; Uridine | 2013 |
Pharmacology of INS37217 [P(1)-(uridine 5')-P(4)- (2'-deoxycytidine 5')tetraphosphate, tetrasodium salt], a next-generation P2Y(2) receptor agonist for the treatment of cystic fibrosis.
Topics: Animals; Astrocytoma; Brain Neoplasms; Calcium; Chlorides; Cilia; Cystic Fibrosis; Deoxycytosine Nucleotides; Epithelial Cells; Humans; In Situ Hybridization; In Vitro Techniques; Indicators and Reagents; Macaca mulatta; Mucins; Mucociliary Clearance; Ophthalmic Solutions; Polyphosphates; Purinergic P2 Receptor Agonists; Receptors, Purinergic P2; Receptors, Purinergic P2Y2; Reverse Transcriptase Polymerase Chain Reaction; Sheep; Tumor Cells, Cultured; Uracil Nucleotides; Uridine | 2002 |
Influence of dTMP on the phenotypic appearance and intracellular persistence of Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Cell Line; Cystic Fibrosis; Dihydropteroate Synthase; Fluorouracil; Folic Acid Antagonists; Humans; Lung; Phenotype; Staphylococcus aureus; Thymidine; Trimethoprim, Sulfamethoxazole Drug Combination; Uridine | 2008 |
Nucleoside uptake in normal and cystic fibrosis fibroblasts in vitro.
Topics: Cells, Cultured; Cystic Fibrosis; Fibroblasts; Humans; Nucleosides; Thymidine; Uridine | 1980 |
Differences in the incorporation of thymidine into DNA of normal and cystic fibrosis fibroblasts in vitro.
Topics: Bromodeoxyuridine; Cadmium; Cell Division; Cell Line; Cystic Fibrosis; DNA; Genotype; Kinetics; Thymidine; Thymidine Kinase; Thymine Nucleotides; Uridine | 1976 |
Activation by extracellular nucleotides of chloride secretion in the airway epithelia of patients with cystic fibrosis.
Topics: Adenosine; Adenosine Triphosphate; Adolescent; Adult; Amiloride; Cell Membrane Permeability; Cells, Cultured; Child; Chlorides; Cystic Fibrosis; Epithelium; Female; Humans; Male; Microelectrodes; Middle Aged; Nasal Mucosa; Receptors, Purinergic; Uridine; Uridine Triphosphate | 1991 |
The methylation of transfer and ribosomal ribonucleic acid in human fibroblasts: normal methylation of ribonucleic acid in cystic fibrosis.
Topics: Adolescent; Adult; Autoradiography; Carbon Radioisotopes; Cells, Cultured; Child; Chromatography; Cystic Fibrosis; Fibroblasts; Humans; Methionine; Methylation; Ribonucleosides; RNA, Ribosomal; RNA, Transfer; Skin; Tritium; Uridine | 1974 |