Page last updated: 2024-10-20

uric acid and Vascular Diseases

uric acid has been researched along with Vascular Diseases in 72 studies

Uric Acid: An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.
uric acid : An oxopurine that is the final oxidation product of purine metabolism.
6-hydroxy-1H-purine-2,8(7H,9H)-dione : A tautomer of uric acid having oxo groups at C-2 and C-8 and a hydroxy group at C-6.
7,9-dihydro-1H-purine-2,6,8(3H)-trione : An oxopurine in which the purine ring is substituted by oxo groups at positions 2, 6, and 8.

Vascular Diseases: Pathological processes involving any of the BLOOD VESSELS in the cardiac or peripheral circulation. They include diseases of ARTERIES; VEINS; and rest of the vasculature system in the body.

Research Excerpts

ExcerptRelevanceReference
"Over the last decade, the biologic interference of uric acid with the cardiovascular (CV) system and the kidney has been intensively investigated, and several experimental studies in animal models and in vitro documented that hyperuricemia may trigger hypertension and incite endothelial dysfunction, vascular damage and renal disease."8.89Uric acid, hypertension, and cardiovascular and renal complications. ( Mallamaci, F; Zoccali, C, 2013)
"Serum uric acid (SUA) level is known to have a prognostic value in patients with acute coronary syndrome (ACS)."7.91Relation of Elevated Serum Uric Acid Level to Endothelial Dysfunction in Patients with Acute Coronary Syndrome. ( Fujimoto, Y; Kitahara, H; Kobayashi, Y; Nakayama, T; Saito, Y, 2019)
" Uric acid is also associated with endothelial dysfunction, oxidative stress, and CVD, raising the hypothesis that an increased serum uric acid might predict ED in patients who are at risk for coronary artery disease (CAD)."7.80Uric acid level and erectile dysfunction in patients with coronary artery disease. ( Akilli, H; Aribas, A; Covic, A; Gaipov, A; Johnson, RJ; Kanbay, M; Kayrak, M; McFann, K; Perez-Pozo, SE; Solak, Y; Turk, S, 2014)
"Serum uric acid (UA) is now beginning to be considered a risk predictor for cardiovascular diseases."7.80Serum uric acid as a risk predictor for erectile dysfunction. ( Heydari, R; Mehrsai, A; Pourmand, G; Salem, S, 2014)
"Plasma fibrinogen content was measured in 20 normal subjects, 20 patients with diabetes mellitus, 20 patients with hyperlipoproteinemia type II or IV (Fredrickson) and 10 patients with hyperuricemia."7.65[Plasma fibrinogen activity in diabetes mellitus, hyperlipoproteinemia and hyperuricemia (author's transl)]. ( Gross, W; Zöller, H, 1976)
"Uric acid is a major product of purine metabolism in humans."6.46Uric acid and the development of hypertension. ( Hwu, CM; Lin, KH, 2010)
"Over the last decade, the biologic interference of uric acid with the cardiovascular (CV) system and the kidney has been intensively investigated, and several experimental studies in animal models and in vitro documented that hyperuricemia may trigger hypertension and incite endothelial dysfunction, vascular damage and renal disease."4.89Uric acid, hypertension, and cardiovascular and renal complications. ( Mallamaci, F; Zoccali, C, 2013)
"Although uric acid is considered an antioxidant in plasma, recent clinical and epidemiological studies have found that hyperuricemia is associated with mortality and development of hypertension, cardiovascular and chronic renal diseases."4.83Hormonal and cytokine effects of uric acid. ( Feig, DI; Franco, M; Herrera-Acosta, J; Johnson, RJ; Kang, DH; Nakagawa, T; Sánchez-Lozada, LG, 2006)
"Serum uric acid (SUA) level is known to have a prognostic value in patients with acute coronary syndrome (ACS)."3.91Relation of Elevated Serum Uric Acid Level to Endothelial Dysfunction in Patients with Acute Coronary Syndrome. ( Fujimoto, Y; Kitahara, H; Kobayashi, Y; Nakayama, T; Saito, Y, 2019)
" One-hundred and seventy-eight CKD patients with hyperuricemia who received febuxostat therapy were included in this study."3.85Identification of chronic kidney disease patient characteristics influencing the renoprotective effects of febuxostat therapy: a retrospective follow-up study. ( Harada, M; Hashimoto, K; Kamijo, Y; Yamada, Y; Yamaguchi, A, 2017)
" Uric acid is also associated with endothelial dysfunction, oxidative stress, and CVD, raising the hypothesis that an increased serum uric acid might predict ED in patients who are at risk for coronary artery disease (CAD)."3.80Uric acid level and erectile dysfunction in patients with coronary artery disease. ( Akilli, H; Aribas, A; Covic, A; Gaipov, A; Johnson, RJ; Kanbay, M; Kayrak, M; McFann, K; Perez-Pozo, SE; Solak, Y; Turk, S, 2014)
" Treating asymptomatic hyperuricemia with urate-lowering drugs such as allopurinol may reduce CV events."3.80Treatment of asymptomatic hyperuricemia and prevention of vascular disease: a decision analytic approach. ( Akkineni, R; Albert, DA; Choi, HK; Lee, A; Miller, KL; Tapp, S; Tosteson, AN; Zhu, Y, 2014)
"Serum uric acid (UA) is now beginning to be considered a risk predictor for cardiovascular diseases."3.80Serum uric acid as a risk predictor for erectile dysfunction. ( Heydari, R; Mehrsai, A; Pourmand, G; Salem, S, 2014)
"Plasma fibrinogen content was measured in 20 normal subjects, 20 patients with diabetes mellitus, 20 patients with hyperlipoproteinemia type II or IV (Fredrickson) and 10 patients with hyperuricemia."3.65[Plasma fibrinogen activity in diabetes mellitus, hyperlipoproteinemia and hyperuricemia (author's transl)]. ( Gross, W; Zöller, H, 1976)
"Uric acid is a major product of purine metabolism in humans."2.46Uric acid and the development of hypertension. ( Hwu, CM; Lin, KH, 2010)
"Uric acid has previously been viewed as a benign solute in serum until it exceeds its saturation level."2.45The role of hyperuricemia in vascular disorders. ( Edwards, NL, 2009)
"Uric acid was associated negatively with FMD% in an age- and gender-adjusted model, while not in the multivariable model."1.40Uric acid and clinical correlates of endothelial function in kidney transplant recipients. ( Asberg, A; Dahle, DO; Dörje, C; Eide, IA; Halden, TA; Hartmann, A; Holdaas, H; Holme, I; Jenssen, T; Mjøen, G; Pihlstrøm, H; Soveri, I, 2014)
"Cardiovascular diseases are the leading cause of death for both women and men."1.40[Gender and subclinical vascular organ damage in patients with coronary artery disease and/or hypertension]. ( Lucyna, WL; Posadzy-Małaczyńska, A, 2014)
"Hyperuricemia is associated with renal disease, but it is usually considered a marker of renal dysfunction rather than a risk factor for progression."1.31A role for uric acid in the progression of renal disease. ( Feng, L; Han, L; Harris, R; Johnson, RJ; Kang, DH; Mazzali, M; Nakagawa, T; Truong, L; Watanabe, S, 2002)
"Hydrochlorothiazide treatment did not prevent the hyperuricemia or arteriolopathy despite controlling blood pressure."1.31Hyperuricemia induces a primary renal arteriolopathy in rats by a blood pressure-independent mechanism. ( Chen, Q; Feng, L; Gordon, KL; Han, L; Johnson, RJ; Kanellis, J; Kang, DH; Lan, HY; Mazzali, M; Nakagawa, T; Watanabe, S; Xia, YY, 2002)
"Analysis of 29 kindred showed hyperlipidemia in half of adult blood relatives; half of these had type III, the remainder usually had sample endogenous hyperglyceridemia (type IV)."1.25The biochemical, clinical, and genetic features of type III hyperlipoproteinemia. ( Fredrickson, DS; Levy, RI; Morganroth, J, 1975)

Research

Studies (72)

TimeframeStudies, this research(%)All Research%
pre-199037 (51.39)18.7374
1990's1 (1.39)18.2507
2000's11 (15.28)29.6817
2010's18 (25.00)24.3611
2020's5 (6.94)2.80

Authors

AuthorsStudies
Hayfron-Benjamin, CF1
van den Born, BJ1
Amoah, AGB1
Maitland-van der Zee, AH1
Meeks, KAC1
Beune, EJAJ1
Klipstein-Grobusch, K1
Agyemang, C1
Liu, P1
Yin, C1
Liu, M1
Chang, L1
Wu, T1
Li, Z1
Luo, R1
Du, X1
Zhao, W1
Nata, N1
Ninwisut, N1
Inkong, P1
Supasyndh, O1
Satirapoj, B1
Dong, W1
Zhang, S1
Yan, S1
Zhao, Z1
Zhang, Z1
Gu, W1
Harada, M2
Fujii, K1
Yamada, Y2
Tsukada, W1
Tsukada, M1
Hashimoto, K2
Kamijo, Y2
Yamaguchi, A1
Cicero, AFG1
Caliceti, C1
Fogacci, F1
Giovannini, M1
Calabria, D1
Colletti, A1
Veronesi, M1
Roda, A1
Borghi, C1
Liu, H1
Liu, J1
Zhao, H1
Zhou, Y1
Li, L1
Wang, H2
Saito, Y1
Kitahara, H1
Nakayama, T1
Fujimoto, Y1
Kobayashi, Y1
Zoccali, C2
Mallamaci, F2
Solak, Y1
Akilli, H1
Kayrak, M1
Aribas, A1
Gaipov, A1
Turk, S1
Perez-Pozo, SE1
Covic, A2
McFann, K1
Johnson, RJ5
Kanbay, M2
Akkineni, R1
Tapp, S1
Tosteson, AN1
Lee, A1
Miller, KL1
Choi, HK1
Zhu, Y1
Albert, DA1
Salem, S1
Mehrsai, A2
Heydari, R1
Pourmand, G2
Dahle, DO1
Jenssen, T1
Holdaas, H1
Asberg, A1
Soveri, I1
Holme, I1
Mjøen, G1
Eide, IA1
Pihlstrøm, H1
Dörje, C1
Halden, TA1
Hartmann, A1
Lucyna, WL1
Posadzy-Małaczyńska, A1
Katsiki, N1
Mikhailidis, DP2
Gigante, A1
Barbano, B1
Barilaro, G1
Quarta, S1
Gasperini, ML1
Di Mario, F1
Romaniello, A1
Amoroso, A1
Cianci, R1
Rosato, E1
Salavati, A1
Allameh, F1
Alizadeh, F1
Namdari, F1
Hosseinian, M1
Salimi, E1
Heidari, F1
Bo, S1
Gambino, R1
Durazzo, M1
Ghione, F1
Musso, G1
Gentile, L1
Cassader, M1
Cavallo-Perin, P1
Pagano, G1
Edwards, NL1
George, J1
Struthers, AD1
Wiernsperger, N1
Geloen, A1
Rapin, JR1
Hwu, CM1
Lin, KH1
Yilmaz, MI1
Sonmez, A1
Turgut, F1
Saglam, M1
Cakir, E1
Yenicesu, M1
Jalal, D1
Jin, M1
Yang, F1
Yang, I1
Yin, Y1
Luo, JJ1
Yang, XF1
Kang, DH4
Nakagawa, T3
Feng, L2
Watanabe, S2
Han, L2
Mazzali, M2
Truong, L1
Harris, R1
KRAMER, DW1
PERILSTEIN, PK1
DE MEDEIROS, A1
GRIEBLE, HG1
JOHNSTON, LC1
FULLER, JB1
KOELBEL, F1
Daskalopoulou, SS1
Athyros, VG1
Elisaf, M1
Kanellis, J2
Sánchez-Lozada, LG1
Feig, DI1
Franco, M1
Herrera-Acosta, J1
Maio, R1
Sesti, G1
Perticone, F1
Hamed, SA1
Hamed, EA1
Hamdy, R1
Nabeshima, T1
Jindal, S1
Singh, M1
Balakumar, P1
Rapado, A1
Marigo, S1
Motti, C1
Gnasso, A1
Bernardini, S1
Massoud, R1
Pastore, A1
Rampa, P1
Federici, G1
Cortese, C1
Xia, YY1
Chen, Q1
Gordon, KL1
Lan, HY1
Morganroth, J1
Levy, RI1
Fredrickson, DS1
Zöller, H1
Gross, W1
Mensen, H1
Ballantyne, D1
Strevens, EA1
Lawrie, TD1
Emmerson, BT1
Medalie, JH2
Papier, CM1
Goldbourt, U2
Herman, JB2
Chait, A1
Mancini, M1
February, AW1
Lewis, B1
Müller-Schweinitzer, E1
Eisenberg, S1
Kwiterovich, PO1
Margolis, S1
Sirtori, CR1
Biasi, G1
Vercellio, G1
Agradi, E1
Malan, E1
Feldman, EB1
Gluck, FB1
Carter, AC1
Diamond, HS1
Wellmann, KF1
Volk, BW1
Johnson, ES1
Buchanan, KD1
Bluhm, GB1
Riddle, JM1
Angelino, PF1
Amati, L1
Dulbecco, A1
Curri, SB1
Tiso, B1
Herrlein, A1
Papier, C1
Tamir, S1
Neufeld, HN1
Riss, E1
Notelovitz, M1
Schneider, V1
Thiele, P1
Tellkamp, F1
Heidelmann, G1
Nolph, KD1
Stoltz, ML1
Maher, JF1
Cammeo, F1
Bourde, C1
Bossa, G1
Giordano, M1
D'Onofrio, F1
Grahame, R1
Scott, JT1
Tägert, J1
Knappe, J1
Knappe, G1
Strube, G1
Dück, KD1
Relke, W1
Borrie, P1
Jouve, A1
Avril, P1
Rouvier, J1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Study on the Effect of Hyperuricaemia on Chronic Renal Disease and Intervention[NCT03425708]Phase 4400 participants (Anticipated)Interventional2017-01-01Recruiting
The Effect of Allopurinol on Malondialdehyde, Nitric Oxide, Kidney Injury Molecule-1 Urine Levels, Resistive Index and Renal Elastography in Kidney Stone Patients After Extra Corporeal Shockwave Lithotripsy[NCT05414669]Phase 435 participants (Actual)Interventional2020-08-06Completed
Value of Uric Acid as Early Predictor of Lupus Nephritis in Assiut University Hospital[NCT05402735]100 participants (Anticipated)Observational2022-06-15Recruiting
Study Protocol for a Prospective Observational Study Investigating the Role of Luminal Pressure on Arteriovenous Fistula Maturation[NCT04017806]60 participants (Anticipated)Observational2018-09-19Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

12 reviews available for uric acid and Vascular Diseases

ArticleYear
Uric acid, hypertension, and cardiovascular and renal complications.
    Current hypertension reports, 2013, Volume: 15, Issue:6

    Topics: Animals; Disease Models, Animal; Humans; Hypertension; Hyperuricemia; Kidney Diseases; Uric Acid; Va

2013
Emerging Vascular Risk Factors in Women: Any Differences from Men?
    Current medicinal chemistry, 2015, Volume: 22, Issue:31

    Topics: Adult; Biomarkers; Female; Humans; Inflammation; Male; Periodontitis; Risk Factors; Sex Factors; Uri

2015
The role of hyperuricemia in vascular disorders.
    Current opinion in rheumatology, 2009, Volume: 21, Issue:2

    Topics: Animals; Biological Evolution; Cardiovascular Diseases; Disease Models, Animal; Humans; Hypertension

2009
Role of urate, xanthine oxidase and the effects of allopurinol in vascular oxidative stress.
    Vascular health and risk management, 2009, Volume: 5, Issue:1

    Topics: Allopurinol; Animals; Antioxidants; Endothelium, Vascular; Enzyme Inhibitors; Humans; Myocardium; Ox

2009
Fructose and cardiometabolic disorders: the controversy will, and must, continue.
    Clinics (Sao Paulo, Brazil), 2010, Volume: 65, Issue:7

    Topics: Diet; Fructose; Humans; Hypertriglyceridemia; Liver; Metabolic Syndrome; Risk Factors; Sweetening Ag

2010
Uric acid and the development of hypertension.
    Medical science monitor : international medical journal of experimental and clinical research, 2010, Volume: 16, Issue:10

    Topics: Animals; Cross-Sectional Studies; Humans; Hypertension; Hyperuricemia; Insulin Resistance; Kidney; R

2010
Uric acid, hyperuricemia and vascular diseases.
    Frontiers in bioscience (Landmark edition), 2012, 01-01, Volume: 17, Issue:2

    Topics: Coronary Disease; Gout; Humans; Hypertension; Hyperuricemia; Inflammasomes; Inflammation; Metabolic

2012
[HYPERURICEMIA AND ITS CLINICAL SIGNIFICANCE].
    Lekarska veda v zahranici, 1963, Sep-20, Volume: 21

    Topics: Blood Chemical Analysis; Carbon Isotopes; Coronary Disease; Humans; Hypertension; Hyperuricemia; Kid

1963
Uric acid as a mediator of endothelial dysfunction, inflammation, and vascular disease.
    Seminars in nephrology, 2005, Volume: 25, Issue:1

    Topics: Animals; Arteries; Biomarkers; Disease Progression; Endothelium, Vascular; Humans; Hyperuricemia; Ur

2005
Hormonal and cytokine effects of uric acid.
    Current opinion in nephrology and hypertension, 2006, Volume: 15, Issue:1

    Topics: Antioxidants; Humans; Hyperuricemia; Muscle, Smooth, Vascular; Uric Acid; Vascular Diseases

2006
Type IV hyperlipoproteinaemia.
    Clinics in endocrinology and metabolism, 1973, Volume: 2, Issue:1

    Topics: Child; Cholesterol; Chylomicrons; Clofibrate; Diagnosis, Differential; Diet Therapy; Dietary Carbohy

1973
Diabetes mellitus and gout.
    Seminars in arthritis and rheumatism, 1972,Fall, Volume: 2, Issue:2

    Topics: Benzothiadiazines; Blood Glucose; Carbohydrate Metabolism; Diabetes Complications; Diabetes Mellitus

1972

Trials

2 trials available for uric acid and Vascular Diseases

ArticleYear
Effects of febuxostat on markers of endothelial dysfunction and renal progression in patients with chronic kidney disease.
    Scientific reports, 2023, 08-18, Volume: 13, Issue:1

    Topics: C-Reactive Protein; Febuxostat; Humans; Hyperuricemia; Kidney; Renal Insufficiency, Chronic; Uric Ac

2023
Effect of apple polyphenols on vascular oxidative stress and endothelium function: a translational study.
    Molecular nutrition & food research, 2017, Volume: 61, Issue:11

    Topics: Antioxidants; Blood Glucose; Body Mass Index; Cells, Cultured; Dietary Supplements; Double-Blind Met

2017

Other Studies

58 other studies available for uric acid and Vascular Diseases

ArticleYear
Associations of Serum Uric Acid Levels With Macrovascular and Renal Microvascular Dysfunction Among Individuals From Sub-Saharan Africa.
    JAMA network open, 2021, 10-01, Volume: 4, Issue:10

    Topics: Adult; Aged; Body Mass Index; Correlation of Data; Cross-Sectional Studies; Female; Ghana; Humans; M

2021
Correlation between 24-Hour Ambulatory Blood Pressure Variability and White Matter Lesions in Patients with Cerebral Small Vascular Disease: A Cross-Sectional Study.
    Computational and mathematical methods in medicine, 2022, Volume: 2022

    Topics: Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cerebrovascular Disorders; Cross-Sectional St

2022
Clinical characteristics of patients with early-onset diabetes mellitus: a single-center retrospective study.
    BMC endocrine disorders, 2023, Oct-10, Volume: 23, Issue:1

    Topics: Adolescent; Adult; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Humans; Ketosis; Male; Re

2023
Relationship between serum uric acid level and vascular injury markers in hemodialysis patients.
    International urology and nephrology, 2020, Volume: 52, Issue:8

    Topics: Aged; Biomarkers; Cross-Sectional Studies; Endothelium, Vascular; Female; Humans; Male; Middle Aged;

2020
Identification of chronic kidney disease patient characteristics influencing the renoprotective effects of febuxostat therapy: a retrospective follow-up study.
    BMC nephrology, 2017, May-18, Volume: 18, Issue:1

    Topics: Adolescent; Adult; Age Distribution; Aged; Aged, 80 and over; Comorbidity; Febuxostat; Female; Follo

2017
Relationship between Serum Uric Acid and Vascular Function and Structure Markers and Gender Difference in a Real-World Population of China-From Beijing Vascular Disease Patients Evaluation Study (BEST) Study.
    Journal of atherosclerosis and thrombosis, 2018, Mar-01, Volume: 25, Issue:3

    Topics: Aged; Ankle Brachial Index; Beijing; Biomarkers; Blood Pressure; Body Mass Index; Carotid Intima-Med

2018
Relation of Elevated Serum Uric Acid Level to Endothelial Dysfunction in Patients with Acute Coronary Syndrome.
    Journal of atherosclerosis and thrombosis, 2019, Apr-01, Volume: 26, Issue:4

    Topics: Acute Coronary Syndrome; Aged; Biomarkers; Endothelium, Vascular; Female; Follow-Up Studies; Humans;

2019
Uric acid level and erectile dysfunction in patients with coronary artery disease.
    The journal of sexual medicine, 2014, Volume: 11, Issue:1

    Topics: Aged; C-Reactive Protein; Coronary Artery Disease; Cross-Sectional Studies; Diabetes Mellitus; Erect

2014
Treatment of asymptomatic hyperuricemia and prevention of vascular disease: a decision analytic approach.
    The Journal of rheumatology, 2014, Volume: 41, Issue:4

    Topics: Aged; Allopurinol; Decision Support Techniques; Female; Follow-Up Studies; Gout Suppressants; Humans

2014
Serum uric acid as a risk predictor for erectile dysfunction.
    The journal of sexual medicine, 2014, Volume: 11, Issue:5

    Topics: Biomarkers; Cardiovascular Diseases; Case-Control Studies; Confidence Intervals; Erectile Dysfunctio

2014
Uric acid and clinical correlates of endothelial function in kidney transplant recipients.
    Clinical transplantation, 2014, Volume: 28, Issue:10

    Topics: Cross-Sectional Studies; Endothelium, Vascular; Female; Follow-Up Studies; Glomerular Filtration Rat

2014
[Gender and subclinical vascular organ damage in patients with coronary artery disease and/or hypertension].
    Przeglad lekarski, 2014, Volume: 71, Issue:3

    Topics: Ankle Brachial Index; Carotid Intima-Media Thickness; Comorbidity; Coronary Disease; Female; Hemodyn

2014
Serum uric acid as a marker of microvascular damage in systemic sclerosis patients.
    Microvascular research, 2016, Volume: 106

    Topics: Adult; Arterial Pressure; Biomarkers; Creatinine; Echocardiography; Female; Humans; Male; Microcircu

2016
Is Serum Uric Acid Level Correlated with Erectile Dysfunction in Coronary Artery Disease Patients?
    Acta medica Iranica, 2016, Volume: 54, Issue:3

    Topics: Adult; Case-Control Studies; Coronary Angiography; Coronary Artery Disease; Erectile Dysfunction; Fe

2016
Associations between serum uric acid and adipokines, markers of inflammation, and endothelial dysfunction.
    Journal of endocrinological investigation, 2008, Volume: 31, Issue:6

    Topics: Adipokines; Biomarkers; Cross-Sectional Studies; Endothelium, Vascular; Humans; Inflammation; Inflam

2008
Serum uric acid level and endothelial dysfunction in patients with nondiabetic chronic kidney disease.
    American journal of nephrology, 2011, Volume: 33, Issue:4

    Topics: Adult; Blood Pressure; C-Reactive Protein; Cholesterol, LDL; Endothelium, Vascular; Female; Glomerul

2011
High-salt diet may cause hypertension. Study suggests excessive salt use may damage blood vessels.
    DukeMedicine healthnews, 2012, Volume: 18, Issue:9

    Topics: Biomarkers; Diet, Sodium-Restricted; Humans; Hypertension; Serum Albumin; Sodium Chloride, Dietary;

2012
A role for uric acid in the progression of renal disease.
    Journal of the American Society of Nephrology : JASN, 2002, Volume: 13, Issue:12

    Topics: Animals; Blood Pressure; Cell Division; Cyclooxygenase 2; Disease Progression; Hypertension; Hypertr

2002
A role for uric acid in the progression of renal disease.
    Journal of the American Society of Nephrology : JASN, 2002, Volume: 13, Issue:12

    Topics: Animals; Blood Pressure; Cell Division; Cyclooxygenase 2; Disease Progression; Hypertension; Hypertr

2002
A role for uric acid in the progression of renal disease.
    Journal of the American Society of Nephrology : JASN, 2002, Volume: 13, Issue:12

    Topics: Animals; Blood Pressure; Cell Division; Cyclooxygenase 2; Disease Progression; Hypertension; Hypertr

2002
A role for uric acid in the progression of renal disease.
    Journal of the American Society of Nephrology : JASN, 2002, Volume: 13, Issue:12

    Topics: Animals; Blood Pressure; Cell Division; Cyclooxygenase 2; Disease Progression; Hypertension; Hypertr

2002
Metabolic influences in vascular disorders with particular reference to cholesterol determinations in comparison with uric acid levels.
    Angiology, 1958, Volume: 9, Issue:3

    Topics: Cholesterol; Humans; Peripheral Vascular Diseases; Uric Acid; Vascular Diseases

1958
Treatment of arterial hypertensive disease with diuretics. II. Effects on electrolytes and uric acid of bendroflumethiazide, potassium chloride, and spironolactone.
    Archives of internal medicine, 1962, Volume: 110

    Topics: Bendroflumethiazide; Diuretics; Electrolytes; Humans; Hypertension; Potassium Chloride; Spironolacto

1962
Uric acid levels and vascular disease.
    Current medical research and opinion, 2004, Volume: 20, Issue:6

    Topics: Diuretics; Greece; Humans; Hypolipidemic Agents; Risk Factors; Uric Acid; Vascular Diseases

2004
Uric acid and endothelial dysfunction in essential hypertension.
    Journal of the American Society of Nephrology : JASN, 2006, Volume: 17, Issue:5

    Topics: Adult; Aged; Biomarkers; Comorbidity; Endothelium, Vascular; Humans; Hypertension; In Vitro Techniqu

2006
Vascular risk factors and oxidative stress as independent predictors of asymptomatic atherosclerosis in adult patients with epilepsy.
    Epilepsy research, 2007, Volume: 74, Issue:2-3

    Topics: Adult; Anticonvulsants; Antioxidants; Atherosclerosis; Blood Glucose; Carotid Arteries; Cholesterol;

2007
Effect of bis (maltolato) oxovanadium (BMOV) in uric acid and sodium arsenite-induced vascular endothelial dysfunction in rats.
    International journal of cardiology, 2008, Aug-29, Volume: 128, Issue:3

    Topics: Animals; Arsenites; Endothelium, Vascular; Male; Pyrones; Rats; Rats, Wistar; Sodium Compounds; Thio

2008
Hypertension and uric acid.
    Lancet (London, England), 1981, Feb-14, Volume: 1, Issue:8216

    Topics: Humans; Hypertension; Uric Acid; Vascular Diseases

1981
[Advances in the treatment of gout and hyperuricemia].
    Revista clinica espanola, 1981, May-31, Volume: 161, Issue:4

    Topics: Anti-Inflammatory Agents; Female; Gout; Humans; Hypertension; Kidney Calculi; Kidney Diseases; Male;

1981
[The behavior of some metabolic and instrumental parameters in diabetics with arteriopathy of the lower extremities treated with increasing doses of glucuronyl-glycosaminoglycano-sulfate].
    La Clinica terapeutica, 1980, Jun-15, Volume: 93, Issue:5

    Topics: Adult; Aged; Blood; Blood Glucose; Cholesterol; Diabetic Angiopathies; Female; Glucuronates; Glycosa

1980
Common mutation in methylenetetrahydrofolate reductase. Correlation with homocysteine and other risk factors for vascular disease.
    Atherosclerosis, 1998, Volume: 139, Issue:2

    Topics: Adult; Female; Genotype; Homocysteine; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); M

1998
Hyperuricemia induces a primary renal arteriolopathy in rats by a blood pressure-independent mechanism.
    American journal of physiology. Renal physiology, 2002, Volume: 282, Issue:6

    Topics: Administration, Oral; Allopurinol; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Con

2002
The biochemical, clinical, and genetic features of type III hyperlipoproteinemia.
    Annals of internal medicine, 1975, Volume: 82, Issue:2

    Topics: Adult; Age Factors; Aged; Cholesterol; Coronary Disease; Female; Glucose Tolerance Test; Humans; Hyp

1975
[Plasma fibrinogen activity in diabetes mellitus, hyperlipoproteinemia and hyperuricemia (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1976, Apr-16, Volume: 118, Issue:16

    Topics: Adult; Aged; Blood Coagulation; Diabetes Mellitus; Female; Fibrinogen; Humans; Hyperlipidemias; Lipo

1976
[Rehabilitation course in patients with peripheral and coronary angio-organopathies. Studies with special reference to serum uric acid and cholesterol under xanthinol nicotinate].
    Therapie der Gegenwart, 1977, Volume: 116, Issue:10

    Topics: Adult; Cholesterol; Coronary Disease; Humans; Hypercholesterolemia; Middle Aged; Theophylline; Uric

1977
Relationship of plasma uric acid to plasma lipids and lipoproteins in subjects with peripheral vascular disease.
    Clinica chimica acta; international journal of clinical chemistry, 1976, Jul-15, Volume: 70, Issue:2

    Topics: Body Weight; Cholesterol; Coronary Disease; Female; Humans; Lipoproteins; Male; Middle Aged; Myocard

1976
Hyperuricaemia--to treat or not?
    Drugs, 1975, Volume: 9, Issue:2

    Topics: Alcohol Drinking; Diet; Endocrine System Diseases; Gout; Hematologic Diseases; Humans; Hyperlipidemi

1975
Major factors in the development of diabetes mellitus in 10,000 men.
    Archives of internal medicine, 1975, Volume: 135, Issue:6

    Topics: Adaptation, Physiological; Adult; Africa, Northern; Age Factors; Asia; Blood Glucose; Blood Pressure

1975
Clinical and metabolic study of alcoholic hyperlipidaemia.
    Lancet (London, England), 1972, Jul-08, Volume: 2, Issue:7767

    Topics: Adult; Alcoholism; Blood Protein Disorders; Diabetes Complications; Diabetes Mellitus; Female; Human

1972
Hyperuricaemia, hypertension, and vascular disease.
    Lancet (London, England), 1967, Jan-14, Volume: 1, Issue:7481

    Topics: Humans; Hypertension; Uric Acid; Vascular Diseases

1967
[Diagnosis and etiology of aseptic femoral head necrosis in adults].
    Zeitschrift fur Orthopadie und ihre Grenzgebiete, 1970, Volume: 108, Issue:2

    Topics: Adult; Age Factors; Alcoholism; Arthritis; Bone Diseases; Cortisone; Female; Femur Head; Follow-Up S

1970
Type 3 hyperlipoproteinaemia.
    Clinics in endocrinology and metabolism, 1973, Volume: 2, Issue:1

    Topics: Adult; Apoproteins; Autopsy; Blood Glucose; Cholesterol; Chylomicrons; Dietary Carbohydrates; Electr

1973
Diet, lipids and lipoproteins in patients with peripheral vascular disease.
    The American journal of the medical sciences, 1974, Volume: 268, Issue:6

    Topics: Adult; Age Factors; Aged; Alcohol Drinking; Angiography; Arteriosclerosis; Cholesterol; Diabetes Com

1974
Microangiopathy in hyperlipidemia and gout.
    The American journal of the medical sciences, 1974, Volume: 268, Issue:5

    Topics: Adolescent; Adult; Age Factors; Aged; Basement Membrane; Biopsy, Needle; Blood Glucose; Body Weight;

1974
Understanding hyperuricemia: nursing implications.
    The Nursing clinics of North America, 1972, Volume: 7, Issue:2

    Topics: Allopurinol; Diabetes Mellitus; Diet Therapy; Gout; Humans; Kidney Diseases; Metabolic Diseases; Uri

1972
Platelets and vascular disease in gout.
    Seminars in arthritis and rheumatism, 1973, Volume: 2, Issue:4

    Topics: Allopurinol; Analgesics; Arteriosclerosis; Blood Platelets; Colchicine; Diabetes Complications; Gout

1973
[Relation between hyperuricemia and dyslipemia].
    Minerva medica, 1973, Oct-06, Volume: 64, Issue:70

    Topics: Adult; Age Factors; Analysis of Variance; Blood Donors; Body Weight; Cholesterol; Female; Humans; Li

1973
The diagnostic significance of the finger-tip biopsy in microangiopathies. Pathology of the arteriovenous anastomoses and preterminal circulation.
    Bibliotheca anatomica, 1973, Volume: 11

    Topics: Adult; Arteriovenous Anastomosis; Biopsy; Cells, Cultured; Connective Tissue; Diabetic Angiopathies;

1973
[The aetiology of myocardial infarction in young people (author's transl)].
    Munchener medizinische Wochenschrift (1950), 1973, Nov-23, Volume: 115, Issue:47

    Topics: Adult; Age Factors; Contraceptives, Oral; Female; Humans; Infections; Male; Metabolic Diseases; Myoc

1973
Diabetes mellitus among 10,000 adult men. I. Five-year incidence and associated variables.
    Israel journal of medical sciences, 1974, Volume: 10, Issue:7

    Topics: ABO Blood-Group System; Adult; Africa, Northern; Age Factors; Aged; Asia; Blood Glucose; Blood Press

1974
The pregnant Natal Indian diabetic.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1969, Apr-05, Volume: 43, Issue:14

    Topics: Adolescent; Adrenal Glands; Adult; Blood Glucose; Body Height; Body Weight; Cholesterol; Escherichia

1969
["Gout" and angioorganopathies].
    Das Deutsche Gesundheitswesen, 1971, Sep-02, Volume: 26, Issue:36

    Topics: Arteriosclerosis Obliterans; Female; Germany, East; Gout; Humans; Male; Uric Acid; Vascular Diseases

1971
Altered peritoneal permeability in patients with systemic vasculitis.
    Annals of internal medicine, 1971, Volume: 75, Issue:5

    Topics: Capillary Permeability; Creatinine; Diabetic Angiopathies; Diffusion; Epithelium; Humans; Hypertensi

1971
[Determination of uric acid in blood. Experimental determination; critical studies of the technics and results].
    Quaderni Sclavo di diagnostica clinica e di laboratorio, 1971, Volume: 7, Issue:2

    Topics: Adolescent; Adult; Aspirin; Autoanalysis; Female; Gout; Humans; Indicators and Reagents; Kidney Dise

1971
[Uricemia in chronic arteriopathy of the extremities. 3. Statistical data on a continuous series of 200 personal cases. 4. Research perspectives].
    Revue de l'atherosclerose et des arteriopathies peripheriques, 1969, Volume: 11, Issue:3

    Topics: Adolescent; Adult; Aged; Arteritis; Gout; Humans; Leg; Male; Middle Aged; Uric Acid; Vascular Diseas

1969
[Clinical and metabolic problems in the degenerative joint disease of the diabetic].
    Revue du rhumatisme et des maladies osteo-articulaires, 1970, Volume: 37, Issue:2

    Topics: Adult; Age Factors; Aged; Arthritis, Rheumatoid; Arthropathy, Neurogenic; Calcaneus; Calcinosis; Dia

1970
Clinical survey of 354 patients with gout.
    Annals of the rheumatic diseases, 1970, Volume: 29, Issue:5

    Topics: Adolescent; Adult; Age Factors; Aged; Alcohol Drinking; Blood Urea Nitrogen; Body Weight; Child; Com

1970
[Results of a comparative cross section study of healthy persons and patients with circulatory disorders in longitudinal epidemiological studies].
    Zeitschrift fur Kreislaufforschung, 1970, Volume: 59, Issue:8

    Topics: Adult; Age Factors; Blood Sedimentation; Body Height; Body Weight; Cholesterol; Electrocardiography;

1970
[Ischemic heart disease and so-called risk factors--results of an epidemiological study in Erfurt].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1971, Jan-01, Volume: 26, Issue:1

    Topics: Angina Pectoris; Blood Glucose; Cardiovascular Diseases; Computers; Coronary Disease; Fatty Acids, E

1971
Type 3 hyperlipoproteinaemia.
    British medical journal, 1969, Jun-14, Volume: 2, Issue:5658

    Topics: Adult; Arteries; Blood Protein Electrophoresis; Cholesterol; Coronary Disease; Diabetes Complication

1969
[On the possible role of alimentary glucides in the genesis and evolution of isolated arteriopathies of the lower extremities].
    Marseille medical, 1966, Volume: 103, Issue:4

    Topics: Arteriosclerosis Obliterans; Blood Glucose; Blood Proteins; Cholesterol; Dietary Carbohydrates; Huma

1966